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ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels最新文献

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Temperature-Controlled Minichannel Flow-Cell for Non-Invasive Particle Measurements in Solid-Liquid Flow 用于固体-液体流动中非侵入性颗粒测量的温控小通道流动池
Mira Schmalenberg, Fabian Sallamon, Christian Haas, N. Kockmann
Solid-liquid suspension flow is often involved in the production of pharmaceuticals and fine chemicals. In these fields, working with continuous small-scale equipment in order to save costs and resources is of increasing interest. Therefore, it is also important to enable process control for small-scale apparatus, which requires the development of new concepts to observe and control crystallization processes in minichannel equipment. The particles and crystals should be detected and measured with as low impact as possible because contact between process medium and the sensors can often lead to the incrustation of the sensor, disturb the particle size and shape, or contaminate the system. For the observation of crystallizing processes in minichannel crystallizers, a non-invasive, temperature-controlled flow-cell is designed in this work. In particular, this flow cell has been designed to examine crystals in a fluorinated ethylene propylene (FEP) tube with an inner diameter of 1.6 mm. Crystals can be investigated using a standard optical camera and microscope. An image processing routine enables the evaluation of crystal size. This is crucial for the assessment of the process and crystal size distribution, which is often a quality criterion in the crystallization process. The contribution will show how the flow-cell for two-phase flow is constructed and the evaluation routine is implemented. Based on experimental data, the applicability of the equipment and the evaluation method are described.
固液悬浮流动常用于药品和精细化学品的生产。在这些领域,为了节省成本和资源,使用连续的小型设备越来越受到关注。因此,实现小型设备的过程控制也很重要,这需要开发新的概念来观察和控制小通道设备中的结晶过程。颗粒和晶体的检测和测量应尽可能降低冲击,因为过程介质与传感器之间的接触通常会导致传感器的结块,扰乱颗粒的大小和形状,或污染系统。为了观察小通道结晶器中的结晶过程,设计了一种非侵入式温控流动池。特别地,该流动池已被设计用于检测内径为1.6毫米的氟化乙丙烯(FEP)管中的晶体。晶体可以用标准的光学照相机和显微镜来研究。图像处理程序使晶体尺寸的评估。这对于过程和晶体尺寸分布的评估是至关重要的,这通常是结晶过程中的质量标准。该贡献将展示如何构建两相流的流池和评估程序的实现。在实验数据的基础上,阐述了该设备的适用性和评价方法。
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引用次数: 4
A Proposed Approach for Accurate Estimation of Interface Surface Area in Multiphase Simulations 一种多相模拟中界面表面积的精确估计方法
S. P. Shipkowski, I. Perez-Raya, S. Kandlikar
Multiphase simulations and computational methods with precisely quantified interfaces are important for variety of engineering applications. A few of these applications are: heat transfer utilizing boiling processes, optimizing combustion, and additive printing/deposition processes. In these applications, calculating the length of the interface between two phases (e.g. a vapor and liquid) is particularly critical. Errors in the calculation of the size of the interface propagate over subsequent time steps thereby producing inaccurate rates of phase-change, fluid velocities, and convection heat transfer. This work proposes a method to reduce the reduce error in interface calculations in multiphase simulations. The proposed method uses the interface inclination and the vapor volume-fraction on each computational cell to compute the interface surface area. Moreover, this work provides details on proper declaration and computation of mass transfer with the Volume-of-Fluid sharp interface tracking algorithm. The performance of the proposed approach is compared with the accepted method that estimates interface surface area with gradients of vapor volume fractions. Computer simulations of spherical bubble growth in superheated liquid demonstrate the relevance of the proposed approach. Results indicate that the errors with the accepted method could propagate to 20% (relative to the theoretical estimation) in the prediction of bubble growth rate and fluid velocities. The proposed approach leads to errors of less than 1% in the prediction of bubble growth rate and fluid velocities.
具有精确量化界面的多相模拟和计算方法在各种工程应用中具有重要意义。其中一些应用是:利用沸腾过程的传热,优化燃烧和添加剂打印/沉积过程。在这些应用中,计算两相(例如蒸气和液体)之间的界面长度是特别关键的。计算界面大小的误差在随后的时间步骤中传播,从而产生不准确的相变速率、流体速度和对流传热。本文提出了一种减少多相仿真中界面计算误差的方法。该方法利用界面倾角和每个计算单元上的蒸气体积分数来计算界面表面积。此外,本文还详细介绍了用流体体积尖锐界面跟踪算法正确声明和计算传质的方法。将该方法的性能与用蒸汽体积分数梯度估计界面表面积的常用方法进行了比较。过热液体中球形气泡生长的计算机模拟证明了所提出方法的相关性。结果表明,该方法对气泡生长速率和流体速度的预测误差可达理论估计的20%。该方法对气泡生长速率和流体速度的预测误差小于1%。
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引用次数: 1
Fundamental Insight on Morphological Changes of Graphene Nanoplatelets-Copper (GNP-Cu) Coatings: Effects of Repetitive Pool Boiling Tests 石墨烯纳米板-铜(GNP-Cu)涂层形态变化的基本见解:重复池沸腾试验的影响
A. Rishi, Anju Gupta
Being an extremely vigorous process involving a continuous intense bubble activity, repetitive pool boiling study is essential for many industrial applications. In this work, we have utilized highly thermally conductive and highly wettable graphene nanoplatelets (GNP) to form GNP-Copper based composite coatings for enhancing the pool boiling heat transfer performance. A multi-step electrodeposition technique was implemented to develop robust coatings on the copper substrates. Repetitive pool boiling studies were conducted on the 2% GNP-Cu coating which achieved the highest CHF of 286 W/cm2 and HTC of 204 kW/m2-°C. After investigating the effect of repetitive boiling on deposited GNP layers and morphology, it was found that GNP were reduced to form r-GNP (reduced GNP) and small increment in pore sizes was observed. Additionally, with repetitive boiling, it was observed that the heat transfer coefficient was continuously increased and compared to pristine copper surface 2% GNP-Cu coating yielded ∼456% increment in HTC at the end of third repetitive test.
作为一个涉及连续剧烈气泡活动的极其剧烈的过程,重复池沸腾研究对于许多工业应用是必不可少的。在这项工作中,我们利用高导热和高可湿性的石墨烯纳米片(GNP)形成GNP-铜基复合涂层,以提高池沸腾传热性能。采用多步骤电沉积技术在铜基底上制备了坚固耐用的涂层。对2% GNP-Cu涂层进行了重复池沸实验,CHF最高达到286 W/cm2, HTC最高达到204 kW/m2-°C。在研究了重复沸腾对沉积GNP层和形貌的影响后,发现GNP被还原为r-GNP(还原GNP),并且观察到孔径的微小增加。此外,通过重复煮沸,观察到传热系数不断增加,与原始铜表面相比,在第三次重复测试结束时,2% GNP-Cu涂层的HTC增加了~ 456%。
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引用次数: 3
A Comparative Analysis of the Tumor Pathology and the Metabolic Heat Generation of Growing Malignant Tumors 恶性肿瘤生长过程中肿瘤病理与代谢热生成的比较分析
A. Owens, M. Godbole, D. Dabydeen, L. Medeiros, P. Phatak, S. Kandlikar
Cancer is one of the most debilitating diseases in the world, affecting over 9.6 million people worldwide every year. Breast cancer remains the second largest cause of death in women. Despite major advances in treatment, over 40,920 women died of breast cancer in 2018 in the United States alone. Early detection of abnormal masses can be crucial for diagnosis and dramatically increase survival. Current screening techniques have varying accuracy and perform poorly when used on heterogeneously and extremely dense breast tissue. Infrared imaging has the potential to detect growing tumors within the breast based on thermal signatures on the breast surface by imaging temperature gradients induced by blood perfusion and tumor metabolic activity. Using clinical patient images, previous methods to estimate tumor properties involve an iterative algorithm to estimate the tumor position and diameter. The details from the MRI are used in estimating the volumetric heat generation rate. This is compared with the published values and the reasons for differences are investigated. The tumor pathology is used in estimating the expected growth rate and compared with the predicted values. The correlation between the tumor characteristics and heat generation rate is fundamental information that is needed in accurately predicting the tumor size and location.
癌症是世界上最使人衰弱的疾病之一,每年影响全世界960多万人。乳腺癌仍然是妇女死亡的第二大原因。尽管在治疗方面取得了重大进展,但仅在美国,2018年就有40920多名女性死于乳腺癌。早期发现异常肿块对于诊断和显著提高生存率至关重要。目前的筛查技术有不同的准确性和表现不佳时,用于异质性和极其致密的乳房组织。红外成像具有检测乳腺内生长肿瘤的潜力,其基于乳房表面的热特征,通过成像由血液灌注和肿瘤代谢活动引起的温度梯度。利用临床患者图像,以往估计肿瘤性质的方法涉及迭代算法来估计肿瘤的位置和直径。核磁共振成像的细节用于估计体积产热率。将其与已发表的数值进行了比较,并对差异的原因进行了研究。肿瘤病理用于估计预期的生长速度,并与预测值进行比较。肿瘤特征与产热率之间的相关性是准确预测肿瘤大小和位置所需的基本信息。
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引用次数: 1
Effect of Wetted Microtexturing on Friction in Microchannel Flow 湿润微织构对微通道流动摩擦的影响
N. Rabiei, C. Hidrovo
Microchannel flows are widely used in applications where small diffusion length scales are important. However, their inherent dimensional constrain also translates into high pumping power requirements. Inspired by nature, one possible method to reduce the large viscous pressure losses is to introduce textures in a microchannel. Depending on the interaction between the textured surface and the liquid, the microstructures can either be wetted or nonwetted. Less adhesion between solid and liquid in nonwetted state has made it popular in most of the friction reduction studies. However, in the nonwetted state, preventing liquid from penetrating into the grooves under pressurized conditions and the gas-liquid interface acting like a solid boundary open space to consider the wetted state for friction reduction as well. When dealing with the wetted state we should be aware that penetration of the flow inside the grooves can induce the pressure drag alongside the skin drag. Therefore, the wetted state will lead to a trade-off between skin and pressure drag. The aim of this work is to understand how different microtextures affect the total drag in a laminar microchannel flow. Textured microchannels with width-to-depth aspect ratios of 1, 10 and 50 and different width of the land region have been tested. In order to perform correct comparisons, the textured and baseline microchannels are designed to have the same volume. The results show that increasing the aspect ratio of the trenches introduces an extermum point in the hydraulic resistance of the microchannels. The optimum aspect ratio for the tested microchannels is 10, in which the trenches are not wide enough for streamlines to bend inside the trenches and increase the skin drag and they are not highly dense along the microchannel to reveal the negative effect of the pressure drag. On the whole, the hydraulic resistance of the textured channels is higher than the equivalent baseline for all the tested geometries.
微通道流广泛应用于小扩散长度尺度很重要的应用中。然而,它们固有的尺寸限制也转化为高抽运功率要求。受大自然的启发,减少巨大粘性压力损失的一种可能方法是在微通道中引入纹理。根据纹理表面与液体之间的相互作用,微观结构可以是湿润的,也可以是非湿润的。非湿润状态下固液之间的粘附性较小,是目前大多数减摩研究的热点。然而,在非润湿状态下,在加压条件下防止液体渗透到沟槽中,并且气液界面像固体边界一样打开空间,以考虑减少摩擦的润湿状态。在处理润湿状态时,我们应该意识到流动在槽内的渗透会引起压力阻力和表面阻力。因此,湿润状态会导致皮肤和压力阻力之间的权衡。这项工作的目的是了解不同的微纹理如何影响层流微通道流动的总阻力。测试了宽度与深度之比分别为1、10和50以及不同陆地区域宽度的纹理微通道。为了进行正确的比较,纹理微通道和基线微通道被设计成具有相同的体积。结果表明,沟槽宽高比的增大会导致微通道的水力阻力出现一个极值。所测试的微通道的最佳宽高比为10,此时沟槽宽度不足以使流线在沟槽内弯曲而增加蒙皮阻力,且沟槽沿微通道的密度不高,以显示压力阻力的负面影响。总的来说,纹理通道的水力阻力高于所有测试几何的等效基线。
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引用次数: 0
Heat Transfer and Fouling Performance During Falling Film Evaporation in Vertical Porous Tubes 垂直多孔管降膜蒸发传热及结垢性能
Lei Wang, Weiyu Tang, Limin Zhao, Wei Li
An experimental investigation was conducted on falling film evaporation along two porous tubes, which were sintered by stainless-steel powder with a diameter of 0.45 and 1 um, respectively. The test section is a 2 m long sintered tube with an outer diameter of 25 mm and a wall thickness of 2 mm. During the experiment, the pressure inside the tube was maintained at 1 atm, the inlet temperature was 373 K, and mass flux ranged from 0.51 to 1.36 kg/ (m s). Conditions of the steam outside the pipe, which was the heat source, were fixed, while the fouling tests were carried out at a constant mass flow of 0.74 kg/ (m s) using high-concentration brine as work fluid. The overall heat transfer coefficient under different working conditions was tested and compared with the stainless steel smooth tube of the same dimensions. The heat transfer coefficient of the two porous stainless tubes are about 35% and 20% lower than that of the smooth one, showing an inferior effect because the steam in the pores of the pipe wall during the infiltration process will reduce the heat conductivity. The heat transfer coefficient of the smooth tube deteriorated severely due to the deposition of calcium carbonate, which had little effect on the sintered tubes. Besides, the fouling weight of porous tubes is 2.01 g and 0 g compared with 5.52 g of the smooth tube.
采用直径分别为0.45 um和1 um的不锈钢粉烧结了两根多孔管,对其降膜蒸发进行了实验研究。试验截面为2 m长烧结管,外径25 mm,壁厚2 mm。实验过程中,管内压力保持在1atm,入口温度为373 K,质量通量范围为0.51 ~ 1.36 kg/ (m s),管内蒸汽作为热源条件固定,以高浓度卤水为工质,以0.74 kg/ (m s)的恒定质量流量进行结垢试验。测试了不同工况下的总换热系数,并与相同尺寸的不锈钢光滑管进行了比较。两种多孔不锈钢管的换热系数分别比光滑不锈钢管低35%和20%左右,表现出较差的效果,因为在渗透过程中,管壁孔隙中的蒸汽会降低导热系数。由于碳酸钙的沉积,光滑管的传热系数严重恶化,而碳酸钙的沉积对烧结管的传热系数影响不大。多孔管的污垢重量分别为2.01 g和0 g,而光滑管的污垢重量为5.52 g。
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引用次数: 0
Numerical Prediction of Dropwise Condensation Performances Over Hybrid Surfaces, Under the Action of Gravity and Vapor Shear 重力和蒸汽切变作用下混合表面水滴凝结性能的数值预测
N. Suzzi, G. Croce, P. D’Agaro
A Lagrangian model following the history of every droplet belonging to an evolving droplets population, originally developed to simulate pattern evolution in the framework of in-flight icing phenomenon, is used in order to simulate dropwise condensation over different shaped micro-structured surfaces. Both the mechanical and the thermal energy balances are solved for every droplet, allowing to predict droplet velocity and condensing flow rate. Coalescence phenomenon is also implemented. The model in the present form is an evolution of the code presented at ICNMM 2019, introducing the effect of vapor shear, a physical model of the evolution of the dynamic contact angle during droplet growth and a prediction of condensing flow rate through the solution of thermal energy balance, thus taking into account the influence of the droplet size. Shared memory parallelization is also carried out decomposing the computational domain into different subdomains, allowing the efficient simulation of a larger number of droplets. Here, the model is validated and used to predict the heat transfer performance of hybrid condensation surfaces, both plane and curved, under the action of both gravity and vapor shear. Starting from literature proposals, several patterns, each characterized by a complex composition of patches with different wettabilities, are numerically investigated and the configuration ensuring the best heat transfer performance and liquid drainage is identified. The sensitivity of the solution with respect to the uncertainty on the estimate of some parameters, such as nucleation density, is also discussed.
采用拉格朗日模型来模拟不同形状的微结构表面上的液滴凝结,该模型最初是为了模拟飞行中结冰现象的模式演变而开发的。每个液滴的机械能和热能平衡都得到了求解,从而可以预测液滴的速度和冷凝流量。还实现了聚结现象。当前形式的模型是对ICNMM 2019上展示的代码的改进,引入了蒸汽剪切的影响,液滴生长过程中动态接触角演变的物理模型,以及通过求解热能平衡来预测冷凝流量,从而考虑了液滴尺寸的影响。共享内存并行化还将计算域分解为不同的子域,从而可以高效地模拟更多的液滴。在此,对该模型进行了验证,并用于预测重力和蒸汽剪切作用下平面和曲面混合冷凝表面的换热性能。从文献建议出发,对几种模式进行了数值研究,每种模式都以具有不同润湿性的斑块的复杂组成为特征,并确定了确保最佳传热性能和液体排出的配置。本文还讨论了溶液对某些参数(如成核密度)估计的不确定度的敏感性。
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引用次数: 0
Performance Evaluation of a New Configuration of Direct Contact Humidification Dehumidification (DCHDH) Desalination System 一种新型直接接触加湿除湿海水淡化系统的性能评价
F. Aguiar, S. Kandlikar
In the present study, the performance of a humidification-dehumidification (HDH) desalination system with the humidifier and the dehumidifier contained in the same enclosure is evaluated. In this design the humidifier system is composed of a vertical copper tube coated with a hydrophilic air-laid paper layer in which saline water is dripped and hot water (from 42.3 to 79.4 °C) flows inside to heat the humidifier system while the dehumidifier consists of an aluminum plate with internal channels for cold water (16 °C) flow. The experimental results show a pure water production rate per unit system volume up to 19.13 L/m3h at a water temperature of 79.4 °C at the evaporator inlet and a hot water mass flow rate of 135 mL/min. This new design has potential for application in desalination systems, especially sin mall systems for use by families living in arid regions.
在本研究中,对加湿器和除湿器位于同一外壳中的加湿-除湿(HDH)海水淡化系统的性能进行了评估。在本设计中,加湿器系统由一根垂直的铜管组成,铜管上涂有一层亲水的空气铺设纸层,管内滴入盐水,热水(42.3 ~ 79.4℃)在管内流动,为加湿器系统加热。除湿器由铝板组成,内部有16℃的冷水通道。实验结果表明,在蒸发器进口水温为79.4℃,热水质量流量为135 mL/min时,单位系统容积的纯水产率可达19.13 L/m3h。这种新设计在海水淡化系统中具有应用潜力,特别是在干旱地区家庭使用的小型系统中。
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引用次数: 0
3D Investigation of Droplet Generation in a Miniaturized Coflowing Device Using Micro-Computed Tomography 微型共流装置中液滴生成的三维微计算机断层扫描研究
J. Schuler, L. Neuendorf, Kai Petersen, N. Kockmann
For many applications, such as liquid-liquid or gas-liquid reactions, the generation of monodisperse droplets is of major interest. Therefore, knowledge about the physics of droplet formation is essential and the subject of numerous studies. Droplet formation is usually investigated using optical cameras, which makes optical accessibility necessary. Furthermore, properties defining droplet evolution is obtained from 2D images. In this work, we present a methodology for the 3D investigation of droplet formation in the laminar regime using micro-computed tomography. A special imaging concept and image processing, incorporating the use of a convolutional neural network, is presented. Water droplets are injected into a continuous polydimethylsiloxane stream in a coflowing configuration using a cannula with an inner diameter di = 800 μm and an outer diameter do = 1050 μm that is centered in a thin polymer tube with an inner diameter di = 1600 μm. Volume flow rates of polydimethylsiloxane and water are varied between 0.2 and 0.3 mL min−1. Furthermore, the influence of cannula positioning on droplet formation is investigated. Different quantitative 3D properties are extracted from the CT scans, such as droplet volume and surface of the interface. Thereby, different stages of droplet formation can be identified and the physical understanding of droplet formation is improved.
对于许多应用,如液-液或气-液反应,单分散液滴的产生是主要的兴趣。因此,关于液滴形成的物理知识是必不可少的,也是许多研究的主题。液滴形成通常使用光学相机进行研究,这使得光学可及性成为必要。此外,从二维图像中获得了定义液滴演化的属性。在这项工作中,我们提出了一种使用微计算机断层扫描对层流状态中液滴形成进行三维研究的方法。提出了一种特殊的成像概念和图像处理,结合了卷积神经网络的使用。将内径为di = 800 μm、外径为do = 1050 μm的套管以内径为di = 1600 μm的细聚合物管为中心,以共流形态将水滴注入聚二甲基硅氧烷连续流中。聚二甲基硅氧烷和水的体积流速在0.2和0.3 mL min - 1之间变化。此外,还研究了导管位置对液滴形成的影响。从CT扫描中提取不同定量的三维属性,如液滴体积和界面表面。从而可以识别液滴形成的不同阶段,提高对液滴形成的物理认识。
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引用次数: 0
Active High-Throughput Micromixer Using Injected Magnetic Mixture Underneath Microfluidic Channel 在微流控通道下注入磁性混合物的主动高通量微混合器
A. Surendran, Ran Zhou
Microfluidics has a lot of applications in fields ranging from pharmaceutical to energy, and one of the major applications is micromixers. A challenge faced by most micromixers is the difficulty in mixing within micro-size fluidic channels because of the domination of laminar flow in a small channel. Hence, magnetic field generated by permanent magnets and electromagnets have been widely used to mix ferrofluids with other sample fluids on a micro level. However, permanent magnets are bulky, and electromagnets produce harmful heat to biological samples; both properties are detrimental to a microfluidic chip’s performance. Taking these into consideration, this study proposes rapid mixing of ferrofluid using a two-layer microfluidic device with microfabricated magnet. Two microfluidic chips that consist of microchannels and micromagnets respectively are fabricated using a simple and low-cost soft lithography method. The custom-designed microscale magnet consists of an array of stripes and is bonded below the plane of the microchannel. The combination of the planar location and angle of the array of magnets allow the migration of ferrofluids, hence mixing it with buffer flow. Parametric studies are performed to ensure comprehensive understanding, including the angle of micro-scale magnets with respect to the fluidic channels, total flow rate and density of the array of magnets. The result from this study can be applied in chemical synthesis and pre-processing, sample dilution, or inducing reactions between samples and reagent.
微流控技术在制药、能源等领域有着广泛的应用,其中最主要的应用之一就是微混合器。由于层流在小通道中占主导地位,大多数微混合器面临的挑战是难以在微尺寸流体通道内混合。因此,由永磁体和电磁铁产生的磁场已被广泛用于在微观水平上混合铁磁流体与其他样品流体。然而,永久磁铁体积庞大,电磁铁会对生物样品产生有害的热量;这两种特性都不利于微流控芯片的性能。考虑到这些,本研究提出了一种双层微流控装置与微制造磁体的快速混合铁磁流体。采用一种简单、低成本的软光刻方法制备了由微通道和微磁体组成的微流控芯片。定制设计的微尺度磁铁由条纹阵列组成,并粘合在微通道平面下方。磁体阵列的平面位置和角度的结合允许铁磁流体的迁移,从而将其与缓冲流混合。进行参数研究以确保全面理解,包括微尺度磁体相对于流体通道的角度,磁体阵列的总流速和密度。本研究结果可应用于化学合成和预处理、样品稀释或诱导样品与试剂之间的反应。
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引用次数: 1
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ASME 2020 18th International Conference on Nanochannels, Microchannels, and Minichannels
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