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Neurological Improvement after Decompression for Dorsal Spine Tuberculosis (TB) 背脊柱结核减压术后神经功能改善
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.692
A. Hussain, Musa Khan, S. Khan, Mumtaz Ali, Akramullah, M. Zubair, M. Mumtaz
Objectives:  To assess the neurological improvement after decompression for dorsal spine tuberculosis in terms of Frankel grading. Materials and Method:  Prospective study was done in the Neurosurgery department, Prime Teaching Hospital Peshawar from 2018 to 2021. Patients of both genders aged between 18 to 60 years were selected while those unfit for surgery or requiring conservative management were excluded from the study. After clinical examination and radiological findings, the patients were diagnosed with dorsal spine tuberculosis requiring surgery. All patients were followed for 3 months post-operatively. Neurological improvement was measured by comparing pre and post-op Frankel grading. Complications were also documented. Results:  Out of 38 patients included in the study, 16 (42%) were male and 22 (58%) were female. The mean age of presentation was 34 ± 5. The distribution for age groups was 18 – 30 (08), 31 – 40 (13), 41 – 50 (11), and 51 – 60 (06). Level of disease D4 – D8 were 17 (44.8%) and D9 – D12 was 21 (55.2%). Pre-operative neurological status of the patients was (5.2%) Frankel A, (10.5%) Frankel B, (47.3) Frankel C, (22%) Frankel D, and (7.8%) Frankel E while Post-operative grading was (2.6%) Frankel A, (5.2%) Frankel B, (23.6%) Frankel C, (47.3%) Frankel D and (18.4) Frankel E. 3 patients experienced worsening of neurology, 2 patients bleeding and CSF leak and 1 patient died as a complication of the surgery. Conclusion:  Surgical option involving decompression of spine TB followed by stabilization is utilized in a majority of patients with neurological deficits. It is very effective and the results are good. The main advantage is thorough debridement and achievement of spinal stabilization. Keywords:   Dorsal Spine Tuberculosis, Frankel Grading, Spinal Stabilization.
目的:用Frankel分级法评价脊背结核减压术后神经功能的改善情况。材料与方法:前瞻性研究于2018 - 2021年在白沙瓦Prime教学医院神经外科进行。选择年龄在18 - 60岁的男女患者,不适合手术或需要保守治疗的患者排除在研究之外。经过临床检查和影像学检查,患者被诊断为脊柱背结核,需要手术治疗。术后随访3个月。通过比较术前和术后Frankel评分来测量神经系统的改善。并发症也有记录。结果:纳入研究的38例患者中,男性16例(42%),女性22例(58%)。平均发病年龄34±5岁。年龄分布为18 ~ 30岁(08)、31 ~ 40岁(13)、41 ~ 50岁(11)、51 ~ 60岁(06)。D4 ~ D8级17例(44.8%),D9 ~ D12级21例(55.2%)。患者术前神经系统状态为Frankel A(5.2%)、Frankel B(10.5%)、Frankel C(47.3%)、Frankel D(22%)、Frankel E(7.8%),术后评分为Frankel A(2.6%)、Frankel B(5.2%)、Frankel C(23.6%)、Frankel D(47.3%)、Frankel E(18.4)。3例患者神经系统恶化,2例出血、脑脊液漏,1例因手术并发症死亡。结论:手术方案包括脊柱结核减压后稳定用于大多数神经功能缺损患者。这是非常有效的,结果很好。主要优点是彻底清创和脊柱稳定。关键词:脊柱背侧结核,Frankel分级,脊柱稳定。
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引用次数: 1
Results of Conservative Management of CSF Rhinorrhea in Post Traumatic Patients 创伤后脑脊液鼻漏的保守治疗结果
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.689
Rana Zubair Mahmood, Mukhtiyar Ahmed Lakho, Talha Abbas, Abdul Wajid, Touqeer Ahmed, Umer Farooq, Sarfraz Khattak
Objectives:  We aimed to see the results of conservative management of CSF rhinorrhea in post-traumatic patients. Material and Methods:  An observational study was conducted on 50 patients for 3 months from 1st November 2021 to 31th Jan 2022. Patients presented to neurosurgery unit II, PINS. All patients had a history of road traffic accidents (RTA). Results:  The age range was 10 – 50 years. The mean age was 25 years. All patients were managed conservatively for one week. We advised complete bed rest to all patients for 2 weeks. Head ends of all patients were slightly inclined from 15 – 30 degrees to reduce pressure in basal cisterns. We gave acetazolamide, mannitol, antibiotics, and anti-epileptic medication to all patients. CSF rhinorrhea in our 43 (86%) patients was stopped completely. In our 5 (10%) patients, CSF rhinorrhea was cured completely after doing a lumbar puncture with drainage of CSF and with the placement of a lumbar drain at a rate of 10 ml per hour. In our 2 (4%) patients, CSF rhinorrhea was not cured. We have to do surgery either by trans cranial or endoscopic repair of CSF rhinorrhea. Conclusion:  CSF rhinorrhea is best cured by conservative management except in 4% of cases.
目的:观察创伤后脑脊液鼻漏的保守治疗效果。材料和方法:从2021年11月1日至2022年1月31日,对50例患者进行了为期3个月的观察性研究。患者被送到神经外科第二单元,PINS。所有患者均有道路交通事故(RTA)史。结果:年龄范围为10 ~ 50岁。平均年龄为25岁。所有患者保守治疗一周。我们建议所有患者完全卧床休息2周。所有患者的头部末端从15 - 30度轻微倾斜,以降低基底池的压力。我们给所有病人开了乙酰唑胺、甘露醇、抗生素和抗癫痫药物。43例(86%)患者的脑脊液鼻漏完全停止。在我们的5例(10%)患者中,脑脊液鼻漏在腰椎穿刺后以每小时10ml的速度引流脑脊液并放置腰椎引流管后完全治愈。在我们的2例(4%)患者中,脑脊液鼻漏未治愈。我们必须通过经颅或内窥镜手术修复脑脊液鼻漏。结论:脑脊液鼻漏除4%外,以保守治疗效果最好。
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引用次数: 0
Results of Endoscopic Septostomy in Isolated Lateral Ventricular Hydrocephalus 内镜下鼻中隔造口术治疗孤立性侧脑室脑积水的效果
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.688
Muhammad Hassan Raza, Iqbal Ahmad, Adnan Khaliq, Zain Saleh
Objective:  To determine the success of endoscopic septostomy in the management of isolated lateral ventricular hydrocephalus. Material and Methods:  A retrospective analysis of data was done and records of all patients who underwent endoscopic septostomy for isolated lateral ventricular hydrocephalus due to any cause for the last 4 years, December 2017 to December 2021 at Punjab Institute of Neurosciences, Lahore. Radiological and clinical outcomes and complications were recorded. A total of 60 cases were reviewed. Results:  Out of 60 patients, 95% were in the age group of 3 – 25 years and 5% were in the age group of 26 – 71 years. There was 54% male whereas 46% were female. Septostomy was successful in relieving hydrocephalus in 75% of cases. Conclusion:  Endoscopic septostomy is an effective procedure for the management of isolated lateral ventricles. Keywords:  Septostomy, Hydrocephalus, Isolated Lateral Ventricles.
目的:探讨内窥镜下鼻中隔造口术治疗孤立性侧脑室脑积水的成功率。材料和方法:回顾性分析了过去4年(2017年12月至2021年12月)在拉合尔旁遮普省神经科学研究所因任何原因进行孤立性侧脑室脑积水内窥镜造口术的所有患者的数据和记录。记录影像学和临床结果及并发症。共审查了60个案例。结果:60例患者中,3 ~ 25岁年龄组占95%,26 ~ 71岁年龄组占5%。男性占54%,女性占46%。中隔造口术治疗脑积水的成功率为75%。结论:内镜下鼻中隔造口术是治疗孤立侧脑室的有效方法。关键词:中隔造口术,脑积水,孤立侧脑室。
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引用次数: 0
Multidisciplinary Management and Outcome of Intradural Extramedullary Spinal Tumors 脊髓硬膜内髓外肿瘤的多学科治疗和预后
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.691
Samra Majeed, Fareeha Majid, N. Tahir, W. Azim, Azam Niaz, A. H. Vohra
Introduction/Objective:  About fifteen percent of the primary CNS tumors are intraspinal. About two-thirds of tumors are intradural extramedullary (IDEM). This study was conducted to review the outcome of operative management of intradural extramedullary tumors in correlation with the factors, both clinical & histopathological, influencing the neurology of patients & prognosis. Materials and Methods:  It was a multicenter study including 42 patients conducted from December 2018 to December 2020. All patients were diagnosed by MRI with and without contrast. Patients were surgically treated & analyzed for clinical features i.e., pain by visual analog scale (VAS) & neurology by modified McCormick scale both preoperatively & post-operatively. Clinical features & outcomes were correlated with tumor size & histopathology. p-value < 0.05 was considered significant. Results:  This study included 42 cases. The most common diagnosis was schwannoma (76.19%). The average intradural space occupied at presentation was 82%. The most common location was dorsal (90.4%). The visual analog score for pain (VAS) improved in all patients post-operatively from 7 ± 1.9 to 2 ± 0.8 (p = 0.003) & modified McCormick scale from 3.0 ± 1.3 to 2.0 ± 1.0 (p = 0.005). The preoperative symptoms were correlated with the only size of the tumor occupying the intradural space (VAS p = 0.021, modified McCormick scale p = 0.018). Conclusion:  All the tumors excised showed some improvement in neurological status. Therefore, all patients diagnosed with IDEM should be operated on even if present with prolonged symptoms or severe neurological compromise. Keywords:  Intradural Extramedullary, Meningioma, Schwannoma, Intraspinal.
简介/目的:约15%的原发性中枢神经系统肿瘤发生在椎管内。约三分之二的肿瘤位于硬膜内髓外(IDEM)。本研究旨在探讨硬膜内髓外肿瘤的手术治疗效果与影响患者神经功能及预后的临床及组织病理学因素的关系。材料与方法:该研究是一项多中心研究,包括42例患者,于2018年12月至2020年12月进行。所有患者均通过MRI进行诊断。对患者进行手术治疗并分析临床特征,即术前和术后用视觉模拟量表(VAS)测量疼痛,用改良McCormick量表测量神经学。临床特征和结果与肿瘤大小和组织病理学相关。p值< 0.05为显著性。结果:本研究纳入42例病例。最常见的诊断为神经鞘瘤(76.19%)。就诊时平均硬膜内占位率为82%。最常见的部位是背部(90.4%)。所有患者术后疼痛视觉模拟评分(VAS)从7±1.9分改善至2±0.8分(p = 0.003),改良McCormick评分从3.0±1.3分改善至2.0±1.0分(p = 0.005)。术前症状仅与肿瘤占据硬膜内间隙的大小相关(VAS p = 0.021,改良McCormick评分p = 0.018)。结论:所有肿瘤切除后神经功能均有一定改善。因此,所有被诊断为IDEM的患者,即使出现长期症状或严重的神经损害,也应进行手术。关键词:硬膜内髓外,脑膜瘤,神经鞘瘤,脊柱内。
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引用次数: 0
Short-Term Complications of Microscopic Trans Nasal Transsphenoidal Pituitary Adenomectomy 显微经鼻蝶垂体腺瘤切除术的短期并发症
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.694
Samra Majeed, Sana Majeed, Muhammad Umair, Shahzaib Tasdique, Waqas Mehdi, Anjum Habib Vohra
Background/Objective:   The commonest of pituitary gland tumors is pituitary adenoma which may be excised transcranially or trans nasal trans sphenoidal using either microscope or endoscope, in this study, the microscope was used. The objective was to see the short-term outcome of patients after microscopic transnasal trans-sphenoidal pituitary adenomectomy. Material & Methods:  This was a descriptive prospective study carried out from July 2019 to July 2021. 80 cases were included. All patients were investigated by contrast brain MRI, hormonal assay for pituitary gland & visual perimetry. Patients were evaluated for complications at 48 hours and 7 days. Results:  Mean age of the study population was 41.78 ± 11.75 years. There were 61 (76%) men & 19 (24%) women. 55 (68.8%) patients had functioning and 25 (3.3%) patients had nonfunctioning adenoma. Among 33 (41.3%) patients size of the adenoma was < 0.9 cm and 47 (58.8%) patients had adenoma > 1.0 cm. 12 patients had CSF leaks within 48 hours of surgery and 5 had a persistent leak on the 7th day. No statistically significant association was seen between age, gender, and size of adenoma and persistent CSF leak (P > 0.05). Diabetes insipidus was found in 9 patients. 3 had post-operative hematoma, 01 patient had meningitis and 2 patients died. Conclusion:  microscopic transnasal trans-sphenoidal surgery is a safe procedure yet associated with significant complications.
背景/目的:垂体腺瘤是最常见的垂体肿瘤,可通过显微镜或内窥镜经经鼻或经蝶窦切除,本研究采用显微镜。目的是观察经鼻蝶垂体腺瘤显微切除术后患者的短期预后。材料与方法:这是一项描述性前瞻性研究,于2019年7月至2021年7月进行。共纳入80例。所有患者均行脑磁共振造影、垂体激素测定及视周检查。分别于48小时和7天对患者进行并发症评估。结果:研究人群平均年龄为41.78±11.75岁。男性61人(76%),女性19人(24%)。55例(68.8%)患者有功能腺瘤,25例(3.3%)患者无功能腺瘤。腺瘤大小< 0.9 cm者33例(41.3%),> 1.0 cm者47例(58.8%)。12例患者在手术48小时内出现脑脊液渗漏,5例患者在第7天出现持续渗漏。年龄、性别、腺瘤大小与持续性脑脊液漏的关系无统计学意义(P > 0.05)。尿崩症9例。术后血肿3例,脑膜炎01例,死亡2例。结论:显微经鼻蝶窦手术是一种安全的手术,但有明显的并发症。
{"title":"Short-Term Complications of Microscopic Trans Nasal Transsphenoidal Pituitary Adenomectomy","authors":"Samra Majeed, Sana Majeed, Muhammad Umair, Shahzaib Tasdique, Waqas Mehdi, Anjum Habib Vohra","doi":"10.36552/pjns.v26i2.694","DOIUrl":"https://doi.org/10.36552/pjns.v26i2.694","url":null,"abstract":"Background/Objective:   The commonest of pituitary gland tumors is pituitary adenoma which may be excised transcranially or trans nasal trans sphenoidal using either microscope or endoscope, in this study, the microscope was used. The objective was to see the short-term outcome of patients after microscopic transnasal trans-sphenoidal pituitary adenomectomy. \u0000Material & Methods:  This was a descriptive prospective study carried out from July 2019 to July 2021. 80 cases were included. All patients were investigated by contrast brain MRI, hormonal assay for pituitary gland & visual perimetry. Patients were evaluated for complications at 48 hours and 7 days. \u0000Results:  Mean age of the study population was 41.78 ± 11.75 years. There were 61 (76%) men & 19 (24%) women. 55 (68.8%) patients had functioning and 25 (3.3%) patients had nonfunctioning adenoma. Among 33 (41.3%) patients size of the adenoma was < 0.9 cm and 47 (58.8%) patients had adenoma > 1.0 cm. 12 patients had CSF leaks within 48 hours of surgery and 5 had a persistent leak on the 7th day. No statistically significant association was seen between age, gender, and size of adenoma and persistent CSF leak (P > 0.05). Diabetes insipidus was found in 9 patients. 3 had post-operative hematoma, 01 patient had meningitis and 2 patients died. \u0000Conclusion:  microscopic transnasal trans-sphenoidal surgery is a safe procedure yet associated with significant complications.","PeriodicalId":19963,"journal":{"name":"Pakistan Journal Of Neurological Surgery","volume":"82 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80144346","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Efficacy of Posterior and Posterolateral Approach for Decompression and Fusion for Thoracolumbar Tuberculosis 后路和后外侧入路对胸腰椎结核减压融合的疗效
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.687
Muhammad Adeel Razzaque, Waqas Noor Chughtai, Sumera Nighat, Muhammad Tahir, Shakeel Ahmad, Moazma Nawaz, Aaiza Rehman
Objective:  To study the efficacy of the posterior and posterolateral approach in thoracolumbar tuberculosis. Material and Methods:  60 patients with thoracolumbar TB spine were enrolled in the study from 2015 to 2021. These patients had single-level disease with low back pain and neurological compromise in lower limbs. The diagnosis was made on an MRI of the spine and elevated ESR levels. All patients were started with antituberculous treatment. The pain was measured on the VAS score, and neurological status was assessed on the ASIA score. Kyphosis angle was calculated on a lateral x-ray of the spine. All patients were operated on by posterior and posterolateral approaches with decompression and fusion. At follow-up, fusion was assessed on every visit by x-ray along with neurological status and pain score. Results:  The mean age of patients was 45.8 years (25 to 66 years). 59.5% patients achieved radiological fusion on follow-up x-rays. There was a significant improvement in VAS score preoperatively mean and SD6.38 ± 1.24to postoperatively 4.45 ± 1.09. The mean and SD of kyphosis in patients preoperatively was 22.3 ± 3.06 to post-operative 22.3 ± 3.06 with a p-value < 0.05 which shows significant improvement. Conclusion:  Posterior and posterolateral decompression and fusion of thoracolumbar tuberculosis is a good surgical approach in respect of neurological outcome, correction of kyphosis, and pain improvement.
目的:探讨后后外侧入路治疗胸腰椎结核的疗效。材料与方法:2015 - 2021年,60例胸腰段结核脊柱患者入组研究。这些患者患有单级疾病,伴有腰痛和下肢神经损伤。诊断是通过脊柱核磁共振检查和ESR水平升高做出的。所有患者均开始接受抗结核治疗。疼痛以VAS评分衡量,神经系统状态以ASIA评分评估。脊柱侧位x线片计算脊柱后凸角。所有患者均经后路和后外侧入路行减压融合手术。随访时,每次就诊均通过x线评估融合情况以及神经状态和疼痛评分。结果:患者平均年龄为45.8岁(25 ~ 66岁)。59.5%的患者在随访x线片上达到放射融合。术前VAS评分平均值(6.38±1.24)至术后sd4.45±1.09均有显著改善。患者术后后凸的平均值为22.3±3.06,SD为22.3±3.06,p值< 0.05,均有显著改善。结论:胸腰椎结核后路和后外侧减压融合术在神经功能、后凸矫正和疼痛改善方面是一种良好的手术入路。
{"title":"Efficacy of Posterior and Posterolateral Approach for Decompression and Fusion for Thoracolumbar Tuberculosis","authors":"Muhammad Adeel Razzaque, Waqas Noor Chughtai, Sumera Nighat, Muhammad Tahir, Shakeel Ahmad, Moazma Nawaz, Aaiza Rehman","doi":"10.36552/pjns.v26i2.687","DOIUrl":"https://doi.org/10.36552/pjns.v26i2.687","url":null,"abstract":"Objective:  To study the efficacy of the posterior and posterolateral approach in thoracolumbar tuberculosis. \u0000Material and Methods:  60 patients with thoracolumbar TB spine were enrolled in the study from 2015 to 2021. These patients had single-level disease with low back pain and neurological compromise in lower limbs. The diagnosis was made on an MRI of the spine and elevated ESR levels. All patients were started with antituberculous treatment. The pain was measured on the VAS score, and neurological status was assessed on the ASIA score. Kyphosis angle was calculated on a lateral x-ray of the spine. All patients were operated on by posterior and posterolateral approaches with decompression and fusion. At follow-up, fusion was assessed on every visit by x-ray along with neurological status and pain score. \u0000Results:  The mean age of patients was 45.8 years (25 to 66 years). 59.5% patients achieved radiological fusion on follow-up x-rays. There was a significant improvement in VAS score preoperatively mean and SD6.38 ± 1.24to postoperatively 4.45 ± 1.09. The mean and SD of kyphosis in patients preoperatively was 22.3 ± 3.06 to post-operative 22.3 ± 3.06 with a p-value < 0.05 which shows significant improvement. \u0000Conclusion:  Posterior and posterolateral decompression and fusion of thoracolumbar tuberculosis is a good surgical approach in respect of neurological outcome, correction of kyphosis, and pain improvement.","PeriodicalId":19963,"journal":{"name":"Pakistan Journal Of Neurological Surgery","volume":"36 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79927059","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Clinical outcome and complication of anterior cranial Fossa meningiomas in tertiary care Hospital Peshawar 白沙瓦三级医院前颅窝脑膜瘤的临床结局及并发症
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.671
A. Hussain, S. Khan, Ramzan Hussain, A. Ihsan, Mumtaz Ali
Objectives:  We examined the surgical outcome and complications of anterior cranial Fossa meningiomas.Materials and Methods:  A prospective study was conducted at the Department of Neurosurgery Prime Teaching Hospital, Peshawar, KPK, Pakistan from June 2019 to June 2021. A total of 31 patients were selected through non-probability consecutive sampling. After clinical examination and radiological findings, the patients were diagnosed with anterior cranial Fossa meningiomas. Microsurgical Trans cranial approaches did. Clinical outcomes and complications were documented. Tumor anterior cranial fossa meningiomas. A low Karnofsky performance scale index was used to analyze the functional impairment of the patients.Results:  9 (29.03%) were male and 22 (70.96%) patients were female. The mean age of presentation was 42 ± 5 years. Headache 25 (80.6%) and Visual loss were the main presenting symptoms 24 (77.5%), and Tuberculum sellae meningioma patients 08 (25.08%). The most common approach was Bifrontal craniotomy for OGM in 9 patients and two small OGM were operated on utilizing frontolateral craniotomy. The rest of the cases were operated through Pterional craniotomy. Tuberculamsalle meningiomas surgery results in a visual improvement in 6 patients (75%), Complete tumor resection was achieved in 22 (70.9%) patients and subtotal resection is achieved in 6 (19.3%) patients. In a few patients 03 (9.67%) only safe debulking and biopsy were taken. Postoperative hemorrhage was in 4 (12.9%) patients.Conclusion:  Transcranial approach for microsurgical resection of anterior cranial fossa meningiomas is an effective and feasible approach in terms of visual outcome and extent of resection.Keywords:  Anterior cranial Fossa Meningioma, Bifrontal Craniotomy, Front-lateral craniotomy.
目的:探讨颅前窝脑膜瘤的手术效果及并发症。材料与方法:一项前瞻性研究于2019年6月至2021年6月在巴基斯坦KPK白沙瓦的神经外科第一教学医院进行。采用非概率连续抽样方法,共选取31例患者。经临床及影像学检查,诊断为颅前窝脑膜瘤。显微外科经颅入路可以。记录临床结果和并发症。颅前窝脑膜瘤。采用低Karnofsky表现指数分析患者的功能损害情况。结果:男性9例(29.03%),女性22例(70.96%)。平均发病年龄42±5岁。头痛25例(80.6%),视力丧失24例(77.5%),鞍结核脑膜瘤08例(25.08%)。9例OGM采用双额开颅,2例小OGM采用额外侧开颅。其余病例均行翼点开颅手术。6例(75%)患者手术视力改善,22例(70.9%)患者肿瘤完全切除,6例(19.3%)患者肿瘤次全切除。少数患者03例(9.67%)只采取了安全的切除和活检。术后出血4例(12.9%)。结论:经颅入路手术切除前颅窝脑膜瘤是一种有效可行的手术入路,不论从视觉效果还是切除范围上看都是可行的。关键词:颅前窝脑膜瘤,双额开颅术,前外侧开颅术
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引用次数: 0
Complications of Microvascular Decompression in patients with Trigeminal Neuralgia 三叉神经痛微血管减压术的并发症
Pub Date : 2022-07-17 DOI: 10.36552/pjns.v26i2.634
Amjad Qaisarani, Rizwan AhmedK han, Irfan Sheikh, M. Fayyaz
Objective:  To determine the frequency of complications of microvascular decompression for patients with trigeminal neuralgia undergoing surgical decompression.Materials and Methods:  A descriptive case study was carried out in the Neurosurgery Unit 1, Lahore General Hospital. The study included 80 patients who fulfilled the inclusion criteria. Informed consent was obtained and possible outcomes and complications of surgery were explained beforehand to the patients. Demographic details were noted. Surgical site infection, CSF leak, Facial numbness, Facial palsy, Hearing impairment, and Postoperative hematoma as complications were assessed. The presence of complications was recorded. Data was stratified for age and gender from. Chi-square was used as a statistical test, taking a p-value ?0.05 as the level of significance.Results:  The study included 80 patients. The mean age of the patients was 40.8 ± 11.7 years. Overall complications were reported in 21 (26.3%) patients. Distribution of complications was as follows; surgical site infection 2 (9.5%), CSF leak (19.0%), facial palsy 5 (23.8%), facial numbness 9 (42.9%), hearing impairment 2 (9.5%) and post-operative hematoma 5 (23.8%).Conclusion:  Microvascular decompression (MVD) is recommended neurosurgical procedure for medically refractory patients with trigeminal pain if there is no contraindication for surgery. Surgical complications can be minimized by meticulous surgery resulting in adequate tissue respect. Another means to get better and long-lasting results with fewer complications is by using an autologous muscle graft.
目的:了解三叉神经痛手术减压患者微血管减压并发症的发生率。材料和方法:在拉合尔总医院神经外科一科进行描述性病例研究。该研究纳入了80名符合纳入标准的患者。获得患者的知情同意,并事先向患者解释手术可能的结果和并发症。注意到人口统计细节。评估手术部位感染、脑脊液泄漏、面部麻木、面瘫、听力障碍和术后血肿等并发症。记录并发症的发生情况。数据按年龄和性别进行分层。统计学检验采用卡方检验,p值为0.05。结果:纳入80例患者。患者平均年龄40.8±11.7岁。21例(26.3%)患者出现并发症。并发症分布如下:手术部位感染2例(9.5%),脑脊液漏(19.0%),面瘫5例(23.8%),面麻9例(42.9%),听力障碍2例(9.5%),术后血肿5例(23.8%)。结论:对于难治性三叉神经痛患者,在无手术禁忌症的情况下,微血管减压(MVD)是推荐的神经外科手术。手术并发症可以通过细致的手术来减少,从而得到充分的组织尊重。另一种方法是使用自体肌肉移植物,以获得更好和更持久的效果,并发症更少。
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引用次数: 0
Increment of High-Grade Gliomas Among Pediatric and Young Adult Population 高级别胶质瘤在儿童和青年人群中的增加
Pub Date : 2022-06-30 DOI: 10.36552/pjns.v26i2.696
Peer Asad Aziz, Muhammad Hamid Ali, Sanaullah Pathan, Mubarak Hussain, Suhail Ahmed Aghani, Riaz Ahmed Raja
Background/Objective:  Glioblastomas are among the commonest primary brain cancers. This study aimed to assess the trend shift of high-grade glioma in our setting among the young and pediatric population. Materials and Methods:  This is a descriptive and cross-sectional study; it was carried out at the Department of Neurosurgery, Liaquat University of Medical and Health Sciences, between duration. All cases with suspected brain tumors, irrespective of age or gender were assessed for glioblastoma. Once a solid tumor was identified on imaging with consistent features of glioblastoma, a provisional diagnosis was established. After that, the patient underwent a brain biopsy. Patients' gender, demographics, clinical presentation, radiologic records, etc. were collected in a predefined proforma. Results:  22 patients were diagnosed with glioblastoma with a high frequency of patients between the age range of 20 to 30 years. The most common location of the tumor was subcortical near the midline. There was slight male predominance. 8 patients had levels of KPS at presentation < 70 and among those two were infants, four were in a vegetative state, and two had a loss of consciousness secondary to increased intracranial pressure. The recurrence rate among those who came back for follow-ups was 27.2%. Conclusion:  Though it is a short study with short follow-up results were astonishing due to perhaps trend shift among Glioblastoma patients, a further detailed workup is needed in different dimensions especially molecular level and genetics to know exactly about the disease and the national registry should be carried and alarmed to identify the problem at once, counter effectively and make a future strategy.
背景/目的:胶质母细胞瘤是最常见的原发性脑癌之一。本研究旨在评估青少年和儿童人群中高级别胶质瘤的趋势转变。材料和方法:这是一项描述性和横断面研究;该研究是在利亚奎特医学和健康科学大学神经外科进行的。所有疑似脑肿瘤的病例,不论年龄或性别,均被评估为胶质母细胞瘤。一旦在影像学上确定实体瘤具有胶质母细胞瘤的一致特征,则建立临时诊断。之后,患者接受了脑活检。患者的性别、人口统计学、临床表现、放射学记录等以预先确定的形式收集。结果:22例患者被诊断为胶质母细胞瘤,患者的高发年龄在20 ~ 30岁之间。肿瘤最常见的位置是靠近中线的皮质下。有轻微的男性优势。8例患者在发病时KPS水平< 70,其中2例为婴儿,4例为植物人状态,2例继发于颅内压升高的意识丧失。复发率为27.2%。结论:虽然本研究时间短,随访时间短,随访结果令人惊讶,但由于胶质母细胞瘤患者的趋势可能发生变化,因此需要进一步从不同维度特别是分子水平和遗传学上进行详细的检查,以准确了解疾病,并应进行国家登记和警报,以便及时发现问题,有效应对并制定未来策略。
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引用次数: 0
Is ENLS (Emergency Neuro Life Support) a need for brain emergencies in recent times? ENLS(紧急神经生命支持)是最近脑紧急情况的需要吗?
Pub Date : 2022-06-30 DOI: 10.36552/pjns.v26i2.701
Muhammad Khurram Ijaz
{"title":"Is ENLS (Emergency Neuro Life Support) a need for brain emergencies in recent times?","authors":"Muhammad Khurram Ijaz","doi":"10.36552/pjns.v26i2.701","DOIUrl":"https://doi.org/10.36552/pjns.v26i2.701","url":null,"abstract":"","PeriodicalId":19963,"journal":{"name":"Pakistan Journal Of Neurological Surgery","volume":"55 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87531769","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Pakistan Journal Of Neurological Surgery
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