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Physical function estimates change in pain following IIPT among children with chronic pain. 身体功能评估慢性疼痛儿童ipt后疼痛的变化。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-02-01 DOI: 10.1111/papr.70009
Mayank Seth, Katherine Bentley, Kathryn Hottinger, Kate Vieni, Anke Reineke, Pritha Dalal

Introduction: Chronic pain can negatively impact a child's quality of life. Pediatric Intensive Interdisciplinary Pain Treatment (IIPT) programs aim to improve overall functioning despite pain through various rehabilitative strategies. It is, however, unclear whether improved function corresponds to self-reported decrease in pain levels. Hence, the purpose of this study is to examine the relationship between changes in physical function and perceived pain among children with chronic pain who have undergone inpatient IIPT.

Materials and methods: A secondary analysis of pre-existing databases of IIPT from two different inpatient acute rehabilitation programs was carried out. Children and adolescents (N = 309; age = 16.2 ± 2.6; 79% females) with chronic pain who attended on average 4-week inpatient IIPT from Nov 2011 to Jan 2023 were included. Participants completed pain intensity (Numerical Pain Rating Scale) and self-reported function measures (Lower Extremity Functional Scale [LEFS], Upper Extremity Functional Index [UEFI], Canadian Occupational Performance Measure [COPM]-Performance, and COPM-Satisfaction) at admission and discharge.

Results: Change in self-reported physical function was significantly associated with change in pain from admission to discharge. After covariate adjustment, self-reported physical function (per the LEFS, UEFI, COPM-Performance, and COPM-Satisfaction) explained 19.8%, 7.8%, 12.0%, and 8.6% of the variance in change in pain, respectively. These measures of self-reported physical function further distinguished between minimal (<30%) and moderate (≥30%) pain reduction.

Conclusions: Self-reported functional gains during IIPT are associated with greater change in perceived pain. Moreover, measures of self-reported physical function can help identify children at risk of minimal pain reduction post-IIPT.

慢性疼痛会对儿童的生活质量产生负面影响。儿科强化跨学科疼痛治疗(IIPT)项目旨在通过各种康复策略改善疼痛的整体功能。然而,目前尚不清楚功能的改善是否与自我报告的疼痛程度的减少相对应。因此,本研究的目的是探讨慢性疼痛儿童在住院接受ipt治疗后身体功能的变化与感知疼痛之间的关系。材料和方法:对两个不同住院急性康复项目中已有的ipt数据库进行了二次分析。儿童和青少年(N = 309;年龄= 16.2±2.6;纳入2011年11月至2023年1月平均4周住院ipt的慢性疼痛患者(79%女性)。参与者在入院和出院时完成疼痛强度(数值疼痛评定量表)和自我报告的功能测量(下肢功能量表[LEFS]、上肢功能指数[UEFI]、加拿大职业绩效量表[COPM]-绩效和COPM-满意度)。结果:自我报告身体功能的变化与入院至出院期间疼痛的变化显著相关。协变量调整后,自我报告的身体功能(根据LEFS、UEFI、copm绩效和copm满意度)分别解释了疼痛变化方差的19.8%、7.8%、12.0%和8.6%。这些自我报告的身体功能的测量进一步区分了最小(结论:ipt期间自我报告的功能增益与感知疼痛的更大变化相关。此外,自我报告的身体功能的测量可以帮助确定儿童在ipt后疼痛减轻的风险。
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引用次数: 0
7. Cervical facet pain: Degenerative alterations and whiplash-associated disorder. 7. 颈椎小关节疼痛:退行性改变和鞭扭伤相关疾病。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-02-01 DOI: 10.1111/papr.70005
M D Hellinga, M van Eerd, M P Stojanovic, S P Cohen, J de Andrès Ares, J W Kallewaard, K Van Boxem, J Van Zundert, M Niesters

Introduction: Pain from the cervical facet joints, either due to degenerative conditions or due to whiplash-related trauma, is very common in the general population. Here, we provide an overview of the literature on the diagnosis and treatment of cervical facet-related pain with special emphasis on interventional treatment techniques.

Methods: A literature search on the diagnosis and treatment of cervical facet joint pain and whiplash-associated disorders (WAD) was performed using PubMed, Cochrane, and Embase databases. All relevant literature was retrieved and summarized.

Results: Facet-related pain is typically diagnosed based on history and physical examination of the patients, combined with a diagnostic block (eg, with local anesthetic) of the medial branches innervating the joints. There is no additive value for imaging techniques to diagnose cervical facet pain, but imaging may be used for procedure planning. First-line therapy for pain treatment includes focused exercise, graded activity, and range-of-motion training. Pharmacological treatment may be considered for acute facet joint pain; however, for chronic facet joint pain, evidence for pharmacological treatment is lacking. Considering the lack of evidence for treatment with botulinum toxin, intra-articular steroid injections, or surgery, these interventions are not recommended. Diagnostic blocks are not considered a viable treatment option, though some patients may experience a prolonged analgesic effect. Long-term analgesia (>6 months) has been observed for radiofrequency treatment of the medial branches.

Conclusions: Cervical facet pain is diagnosed based on history, physical examination, and a diagnostic block of the medial branches innervating the painful joints. Conservative management, including exercise therapy, is the first line of treatment. When conservative management does not result in adequate improvement of pain, radiofrequency treatment of the medial branches should be considered, which often results in adequate pain relief.

导论:颈椎小关节的疼痛,无论是由于退行性疾病还是由于鞭打相关的创伤,在普通人群中非常常见。在这里,我们提供了一个文献综述的诊断和治疗颈面相关的疼痛,特别强调介入治疗技术。方法:使用PubMed、Cochrane和Embase数据库检索有关颈椎小关节痛和鞭扭伤相关疾病(WAD)诊断和治疗的文献。检索并总结所有相关文献。结果:关节面相关性疼痛的诊断通常基于患者的病史和体格检查,并结合神经支配关节的内侧分支的诊断阻滞(如局部麻醉)。影像学技术在诊断颈椎关节突疼痛方面没有附加价值,但影像学可用于手术计划。疼痛治疗的一线疗法包括集中运动、分级活动和活动范围训练。急性小关节痛可考虑药物治疗;然而,对于慢性小关节疼痛,缺乏药物治疗的证据。考虑到缺乏肉毒杆菌毒素、关节内类固醇注射或手术治疗的证据,不推荐这些干预措施。诊断阻滞不被认为是一种可行的治疗选择,尽管一些患者可能会经历长时间的镇痛效果。长期镇痛(bbb6个月)已观察到射频治疗的内侧分支。结论:颈小关节疼痛的诊断是基于病史、体格检查和对疼痛关节的神经内侧分支的诊断阻滞。保守治疗,包括运动疗法,是治疗的第一线。当保守治疗不能使疼痛得到充分改善时,应考虑对内侧分支进行射频治疗,这通常会使疼痛得到充分缓解。
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引用次数: 0
Wearable, noninvasive, pulsed shortwave (radiofrequency) therapy for postoperative analgesia: A randomized, double-masked, sham-controlled pilot study. 可穿戴、无创、脉冲短波(射频)治疗术后镇痛:一项随机、双盲、假对照的初步研究。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-02-01 DOI: 10.1111/papr.70007
Brian M Ilfeld, John J Finneran, Engy T Said, Scott T Ball, Anne M Wallace, Ryan C Broderick, Bryan J Sandler, Jay J Doucet, Sandy R Hu, Brannon J Cha, Adhithi Narayana Murthy, Baharin Abdullah

Background: Nonthermal, pulsed shortwave (radiofrequency) therapy (PSWT) is a nonpharmacologic, noninvasive modality that limited evidence suggests provides analgesia. Its potential favorable risk-benefit ratio stems from its lack of side effects and significant medical risks, applicability to any anatomic location, long treatment duration, and ease of application by simply affixing it with tape. Even with a relatively small treatment effect, PSWT might contribute to a multimodal analgesic regimen, similar to acetaminophen. However, widespread clinical use is hindered by a lack of systematic evidence. The current randomized, controlled pilot study was undertaken to determine the feasibility and optimize the protocol for a subsequent definitive investigation and estimate the treatment effect of PSWT on postoperative pain and opioid consumption.

Methods: Within the recovery room following primary knee and hip arthroplasty, cholecystectomy, hernia repair, and non-mastectomy breast surgery, we applied 1-3 PSWT devices (Model 088, BioElectronics Corporation, Frederick, Maryland) over the surgical bandages. Participants were randomized to 28 days of either active or sham treatment in a double-masked fashion. The outcomes of primary interest were the cumulative opioid consumption and the mean of the "average" and "worst" daily pain measured with the Numeric Rating Scale over the first 7 postoperative days.

Results: During the first 7 postoperative days, oxycodone consumption in participants given active treatment (n = 55) was a mean (SD) of 21 mg (24) versus 17 mg (26) in patients given sham (n = 57): difference 4 (95% CI, -5 to 13), p = 0.376. During this same period, the "average" daily pain intensity in patients given active treatment was 2.4 (1.6) versus 2.6 (1.7) in sham: difference -0.2 (95% CI -0.8 to 0.5), p = 0.597. Concurrently, the worst/maximum pain for the active group was 4.6 (2.0) versus 4.7 (2.1) in sham: difference -0.1 (95% CI -0.8 to 0.7), p = 0.888. No device-related systemic side effects or serious adverse events were identified.

Conclusions: Pulsed shortwave (radiofrequency) therapy did not reduce pain scores and opioid requirements to a statistically significant or clinically relevant degree during the initial postoperative week in this pilot study. These results must be replicated with a subsequent study before being considered definitive. Data from this preliminary study may be used to help plan future trials.

背景:非热、脉冲短波(射频)治疗(PSWT)是一种非药物、无创的治疗方式,有限的证据表明它能起到镇痛作用。其潜在的良好风险效益比源于其无副作用和显著的医疗风险,适用于任何解剖部位,治疗时间长,只需用胶带粘贴即可使用。即使治疗效果相对较小,PSWT也可能有助于多模式镇痛方案,类似于对乙酰氨基酚。然而,由于缺乏系统的证据,广泛的临床应用受到阻碍。目前进行的随机对照试点研究是为了确定可行性并优化方案,以进行后续的明确调查,并评估PSWT对术后疼痛和阿片类药物消耗的治疗效果。方法:在初级膝关节和髋关节置换术、胆囊切除术、疝修补术和非乳房切除术后的恢复室内,我们在手术绷带上应用了1-3个PSWT装置(型号088,BioElectronics Corporation, Frederick, Maryland)。参与者被随机分为28天的积极或虚假治疗,以双重掩盖的方式。主要关注的结果是阿片类药物的累积消耗以及术后前7天用数字评定量表测量的“平均”和“最严重”每日疼痛的平均值。结果:术后前7天,接受积极治疗的患者(n = 55)的氧可酮消耗量平均(SD)为21 mg(24),而接受假治疗的患者(n = 57)的氧可酮消耗量为17 mg(26):差异为4 (95% CI, -5至13),p = 0.376。在同一时期,接受积极治疗的患者的“平均”每日疼痛强度为2.4(1.6),而接受假治疗的患者为2.6(1.7):差异为-0.2 (95% CI -0.8至0.5),p = 0.597。同时,活动组的最大/最差疼痛为4.6(2.0),而假手术组为4.7(2.1):差异为-0.1 (95% CI -0.8 ~ 0.7), p = 0.888。未发现与器械相关的全身副作用或严重不良事件。结论:在这项初步研究中,脉冲短波(射频)治疗在术后最初一周内并没有将疼痛评分和阿片类药物需求降低到统计学显著或临床相关的程度。这些结果必须在随后的研究中得到证实,才能被认为是决定性的。这项初步研究的数据可用于帮助计划未来的试验。
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引用次数: 0
The comparison of spread of methylene blue after the Pericapsular Nerve Group block and a double injection selectively targeting the articular branches to the anterior hip capsule in human cadavers. 亚甲蓝在人尸体中囊周神经群阻滞和选择性靶向髋关节前囊关节分支双重注射后扩散的比较。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-02-01 DOI: 10.1111/papr.70002
Rachel J H Smits, Edward C T H Tan, Luuk R van den Bersselaar, Anne de Bruijn, Eva Hendriksen, Kris C P Vissers, Kim T E Olde Dubbelink, Selina E I van der Wal

Objectives: In this study, the spread of methylene blue was compared between an ultrasound-guided Pericapsular Nerve Group (PENG) block and a double injection technique, where the approach towards the inferomedial acetabulum was added to the latter.

Methods: The two techniques were performed in 11 fresh frozen cadavers. The spread was measured after anatomical dissection in which the supplying femoral and obturator nerves were identified.

Results and conclusion: Our study demonstrates adequate staining of the iliac bone with comparable distal and medial spread in both techniques, indicating that the PENG block with a single injection is adequate in blocking the hip capsule with 10 mL local anesthetics. Staining of the femoral nerve occurred in 2/6 specimens after the PENG block, and staining of the obturator nerve in 1 specimen in each group.

目的:在本研究中,比较了超声引导下的囊包膜神经组(PENG)阻滞和双注射技术之间的亚甲蓝扩散,双注射技术向髋臼内侧内侧增加了入路。方法:在11具新鲜冷冻尸体上进行两种技术。在解剖解剖后,确定了供应股神经和闭孔神经,测量了扩散。结果和结论:我们的研究表明,在这两种技术中,髂骨的远端和内侧扩散都有足够的染色,表明单次注射PENG阻滞足以用10ml局麻药阻断髋关节囊。彭阻滞后2/6例标本出现股神经染色,每组1例标本出现闭孔神经染色。
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引用次数: 0
Triptan treatment is associated with a higher number of red wine-induced migraine episodes: An exploratory questionnaire-based survey. 服用阿普唑仑与红葡萄酒诱发偏头痛发作次数增加有关:一项基于问卷的探索性调查。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-09-01 DOI: 10.1111/papr.13412
Saad Masood, Muhammad Ahrar Bin Naeem, Muhammad Qasim, Javeeria Arshad
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引用次数: 0
11. Cervicogenic headache and occipital neuralgia. 11.颈源性头痛和枕神经痛。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-09-01 DOI: 10.1111/papr.13405
Nicole Lefel, Hans van Suijlekom, Steven P C Cohen, Jan Willem Kallewaard, Jan Van Zundert

Introduction: Cervicogenic headache (CEH) and occipital neuralgia (ON) are headaches originating in the occiput and that radiate to the vertex. Because of the intimate relationship between structures based in the occiput and those in the upper cervical region, there is significant overlap between the presentation of CEH and ON. Diagnosis starts with a headache history to assess for diagnostic criteria formulated by the International Headache Society. Physical examination evaluates range of motion of the neck and the presence of tender areas or pressure points.

Methods: The literature for the diagnosis and treatment of CEH and ON was searched from 2015 through August 2022, retrieved, and summarized.

Results: Conservative treatment includes pain education and self-care, analgesic medication, physical therapy (such as reducing secondary muscle tension and improving posture), the use of TENS (transcutaneous electrical nerve stimulation), or a combination of the aforementioned treatments. Injection at various anatomical locations with local anesthetic with or without corticosteroids can provide pain relief for a short period. Deep cervical plexus block can result in improved pain for less than 6 months. In both CEH and ON, an occipital nerve block can provide important diagnostic information and improve pain in some patients, with PRF providing greater long-term pain control. Radiofrequency ablation of the cervical facet joints can result in improvement for over 1 year. Occipital nerve stimulation (ONS) should be considered for the treatment of refractory ON.

Conclusion: The treatment of CEH preferentially consists of radiofrequency treatment of the facet joints, while for ON, pulsed radiofrequency of the occipital nerves is indicated. For refractory cases, ONS may be considered.

导言:颈源性头痛(CEH)和枕神经痛(ON)是源于枕部并放射至顶点的头痛。由于枕部结构与上颈部结构之间的密切关系,颈源性头痛和枕神经痛的表现形式有很大的重叠。诊断首先要了解头痛病史,评估是否符合国际头痛协会制定的诊断标准。体格检查主要评估颈部的活动范围以及是否存在压痛区或压痛点:方法:检索了2015年至2022年8月有关CEH和ON诊断和治疗的文献,并进行了检索和总结:保守治疗包括疼痛教育和自我护理、镇痛药物、物理治疗(如减轻继发性肌肉紧张和改善姿势)、使用TENS(经皮神经电刺激)或上述治疗方法的组合。在不同的解剖位置注射局部麻醉剂,同时使用或不使用皮质类固醇,可在短期内缓解疼痛。深部颈丛神经阻滞可使疼痛在 6 个月内得到改善。在 CEH 和 ON 中,枕神经阻滞可提供重要的诊断信息,并改善部分患者的疼痛,而 PRF 可提供更好的长期疼痛控制。颈椎面关节射频消融术可使疼痛改善超过 1 年。在治疗难治性颈椎病时,应考虑使用枕神经刺激疗法(ONS):结论:治疗颈椎病的首选方法是对关节面进行射频治疗,而治疗颈椎病的方法则是对枕神经进行脉冲射频治疗。对于难治性病例,可考虑使用 ONS。
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引用次数: 0
Diagnosing persistent spinal pain syndrome type 2. 诊断持续性脊柱疼痛综合征2型。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 DOI: 10.1111/papr.13447
Alaa Abd-Elsayed, Christopher Gilligan
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引用次数: 0
High-frequency spinal cord stimulation in treatment of phantom lower limb pain following spinal cord injury: A case report. 高频脊髓刺激治疗脊髓损伤后的下肢幻痛:病例报告。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-11-20 DOI: 10.1111/papr.13437
Rachel J Park, Tillman W Boesel, Antonio Di Ieva

Introduction: Pain management in patients with complete spinal cord injury is complex.

Case report: We report a successful case of managing neuropathic, phantom limb, and back pain below the level of spinal cord injury (T5 American Spinal Injury Association [ASIA] A) using a 10 kHz high-frequency spinal cord stimulator (SCS) over a 6-month follow-up period.

Conclusion: The effectiveness of this approach may be attributed to its ability to modulate supraspinal pain processing, allowing for targeted relief of various pain mechanisms below the level of injury.

简介完全性脊髓损伤患者的疼痛治疗非常复杂:我们报告了一例使用 10 kHz 高频脊髓刺激器(SCS)治疗脊髓损伤水平(T5 美国脊髓损伤协会 [ASIA] A)以下神经病理性疼痛、幻肢痛和背痛的成功病例,随访期为 6 个月:结论:这种方法之所以有效,可能是因为它能够调节脊髓上疼痛处理过程,从而有针对性地缓解受伤部位以下的各种疼痛机制。
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引用次数: 0
The influence of pain on community reintegration after spinal cord injury. 脊髓损伤后疼痛对重新融入社区的影响。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-11-19 DOI: 10.1111/papr.13439
Valerie Henderson, Mokgadi Kholofelo Mashola

Background: Community reintegration is an important goal for people living with a spinal cord injury (SCI), and pain is suspected to limit reintegration due to its limitations in daily functioning, mood, and sleep.

Objectives: To determine the influence of pain on community reintegration in manual wheelchair users with SCI.

Methods: The Reintegration to Normal Living Index was used to determine community reintegration, while the DN4 and the Wheelchair User's Shoulder Pain Index were used to determine the presence of neuropathic and shoulder pain respectively. Associations and differences between the pain variables and participants with and without pain were analyzed with Spearman correlations and Mann-Whitney U-tests using SPSS v27 at 0.05 significance level and 95% confidence interval.

Results: Of the 122 participants, 85.2% reported current pain, with a 77.7% median for community reintegration. Neuropathic pain (53.3%) was more common and severe than nociceptive shoulder pain (14.8%). There was no significant difference in community reintegration between participants with and without pain, nor any correlation between the overall presence of pain and community reintegration. The severity of pain, particularly shoulder pain, was negatively associated with taking trips out of town (p < 0.01), and overall community reintegration (p < 0.05).

Conclusion: It is not the mere presence of pain that influences community reintegration, but rather the severity and the location of pain. Shoulder care and pain management need to be included in the rehabilitation program, as these are important considerations when rehabilitating people with SCI back into their communities.

背景:重返社区是脊髓损伤(SCI)患者的重要目标:重新融入社区是脊髓损伤(SCI)患者的一个重要目标,而疼痛因其对日常功能、情绪和睡眠的限制而被怀疑会限制患者重新融入社区:确定疼痛对脊髓损伤手动轮椅使用者重新融入社区的影响:方法:使用 "重新融入正常生活指数"(Reintegration to Normal Living Index)来确定重新融入社区的情况,而 "DN4 "和 "轮椅使用者肩部疼痛指数"(Wheelchair User's Shoulder Pain Index)则分别用于确定是否存在神经病理性疼痛和肩部疼痛。在 0.05 的显著性水平和 95% 的置信区间下,使用 SPSS v27 进行斯皮尔曼相关性检验和曼-惠特尼 U 检验,分析了疼痛变量与有疼痛和无疼痛参与者之间的关联和差异:在122名参与者中,85.2%的人报告目前存在疼痛,重返社区的中位数为77.7%。神经性疼痛(53.3%)比肩痛性疼痛(14.8%)更为常见和严重。有疼痛和无疼痛的参与者在重新融入社区方面没有明显差异,总体疼痛程度与重新融入社区之间也没有任何相关性。疼痛的严重程度,尤其是肩部疼痛,与出城旅行呈负相关(p 结论:疼痛的严重程度与出城旅行呈负相关:影响重返社区的因素并不仅仅是疼痛的存在,而是疼痛的严重程度和部位。肩部护理和疼痛管理需要纳入康复计划,因为这是让 SCI 患者重返社区的重要考虑因素。
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引用次数: 0
Lead fracture in dorsal root ganglion stimulation. 背根神经节刺激中的引线断裂。
IF 2.5 3区 医学 Q2 ANESTHESIOLOGY Pub Date : 2025-01-01 Epub Date: 2024-11-04 DOI: 10.1111/papr.13434
Alaa Abd-Elsayed, Christopher Gilligan
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引用次数: 0
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Pain Practice
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