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Infections following Immediate Implant-Based Breast Reconstruction: A Case-Control Study over 11 Years. 即刻假体乳房重建术后的感染:超过11年的病例对照研究。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006202
Joseph Banuelos, M. Sabbagh, Si-Gyun Roh, M. Nguyen, V. Lemaine, N. Tran, S. Jacobson, J. Boughey, J. Jakub, T. Hieken, A. Degnim, J. Mandrekar, E. Berbari, Basel Sharaf
BACKGROUNDSurgical-site infection after implant-based breast reconstruction adversely affects surgical outcomes and increases health care costs. This 11-year case-control study examines risk factors specific for surgical-site infection after immediate tissue expander/implant-based breast reconstruction.METHODSThe authors performed a retrospective review to identify all consecutive patients with breast implant infections between 2006 and 2016. Patients who developed surgical-site infection after immediate tissue expander/implant-based breast reconstruction were included. Surgical-site infection was defined using the Centers for Disease Control and Prevention criteria; specifically, infections requiring hospital admission, intravenous antibiotics, or surgical intervention were included. The authors matched a control patient to each infection case by patient age and date of surgery. Patient demographics, medical comorbidities, and perioperative surgical variables were examined. Univariate and multivariable conditional logistic regression models were constructed.RESULTSA total of 270 breasts in 252 patients were evaluated. On multivariate analysis, patients with a higher body mass index (OR, 1.1 per 1 body mass index point increase; 95 percent CI, 1.0 to 1.2; p = 0.02), hypertension (OR, 6.5; 95 percent CI, 1.9 to 22.3; p = 0.002), neoadjuvant chemotherapy (OR, 2.6; 95 percent CI, 1.0 to 6.3; p = 0.04), axillary lymph node dissection (OR, 7.1; 95 percent CI, 1.7 to 29.2; p = 0.006), seroma formation (OR, 15.34; 95 percent CI, 3.7 to 62.5; p = 0.0001), and wound healing complications (OR, 23.91; 95 percent CI, 6.1 to 93.4; p < 0.0001) were significantly associated with surgical-site infection.CONCLUSIONSWomen with obesity, women with hypertension, and those treated with neoadjuvant chemotherapy are at increased risk of surgical-site infection. Further risks are also associated with postoperative seroma and wound complications. This may help patient selection and counseling, adjusted based on risk factors regarding complications of immediate implant-based breast reconstruction.CLINICAL QUESTION/LEVEL OF EVIDENCERisk, III.
背景:假体乳房重建术后手术部位感染会对手术结果产生不利影响,并增加医疗保健费用。这项为期11年的病例对照研究探讨了即刻组织扩张器/假体乳房重建术后手术部位感染的特定危险因素。方法对2006年至2016年间所有连续发生乳房植入物感染的患者进行回顾性分析。包括在立即组织扩张器/假体乳房重建后发生手术部位感染的患者。手术部位感染的定义采用疾病控制和预防中心的标准;具体来说,包括需要住院、静脉注射抗生素或手术干预的感染。作者根据患者的年龄和手术日期将对照患者与每个感染病例进行匹配。检查了患者人口统计学、医疗合并症和围手术期手术变量。建立了单变量和多变量条件logistic回归模型。结果252例患者共270个乳房进行了tsa评估。多因素分析显示,体重指数升高的患者(OR为1.1 /体重指数升高1点;95% CI, 1.0 ~ 1.2;p = 0.02),高血压(OR, 6.5;95% CI, 1.9 - 22.3;p = 0.002),新辅助化疗(OR, 2.6;95% CI, 1.0 ~ 6.3;p = 0.04),腋窝淋巴结清扫(OR, 7.1;95% CI, 1.7 - 29.2;p = 0.006),血清形成(OR, 15.34;95% CI, 3.7 - 62.5;p = 0.0001),伤口愈合并发症(OR, 23.91;95% CI, 6.1 - 93.4;P < 0.0001)与手术部位感染显著相关。结论肥胖妇女、高血压妇女和接受新辅助化疗的妇女手术部位感染的风险增加。进一步的风险还与术后血清肿和伤口并发症有关。这可能有助于患者的选择和咨询,调整基于即刻假体乳房重建并发症的风险因素。临床问题/证据风险水平,3。
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引用次数: 22
Rasch Analysis of the Patient and Observer Scar Assessment Scale in Linear Scars: Suggestions for a Patient and Observer Scar Assessment Scale v2.1. 线性疤痕中患者与观察者疤痕评定量表的Rasch分析:对患者与观察者疤痕评定量表v2.1的建议
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006265
F. Franchignoni, A. Giordano, S. Vercelli, Elisabetta Bravini, Valeria Stissi, G. Ferriero
BACKGROUNDThe Patient and Observer Scar Assessment Scale (POSAS) v2.0 is a widely used instrument to evaluate postsurgical scars. Its two subscales respectively investigate the patient's and clinician's opinion on the scar quality. However, psychometric studies of the POSAS have indicated that its metric performance is suboptimal, and structural adjustments may be appropriate. The authors aimed to verify through Rasch analysis the measurement properties of the POSAS v2.0, and propose eventual structural refinements for an easier and more confident use of the scale in clinical practice and research.METHODSConsecutive patients admitted to two rehabilitation centers for postsurgery rehabilitation over a 2-year period underwent scar assessments with the POSAS v2.0. We performed Rasch analysis to examine the scale's dimensionality, rating categories, item fit, reliability indices, local item independence, and differential item functioning.RESULTSThe study population consisted of 115 patients. The 10 response options of the POSAS showed malfunctioning, and thus were collapsed, forming a parsimonious five-level rating scale, which helped to improve the measurement accuracy. After that, unidimensionality of both subscales was confirmed. Then, internal construct validity of the POSAS v2.0 was demonstrated (through item fit to the Rasch model). Reliability indices were high (≥0.80). No significant differential item functioning was detected concerning age or sex.CONCLUSIONThis study demonstrates the good psychometric properties of a simplified Rasch-based version of the Patient and Observer Scar Assessment Scale with five response options (POSAS v2.1) in patients with postsurgical linear scars, and provides insights for future refinement of the tool.
患者和观察者疤痕评估量表(POSAS) v2.0是一种广泛使用的评估手术后疤痕的工具。它的两个分量表分别考察患者和临床医生对疤痕质量的看法。然而,POSAS的心理测量学研究表明,其度量性能是次优的,结构调整可能是适当的。作者旨在通过Rasch分析验证POSAS v2.0的测量特性,并提出最终的结构改进,以便在临床实践和研究中更容易和更自信地使用该量表。方法连续2年在2家康复中心接受术后康复治疗的患者采用POSAS v2.0进行疤痕评估。我们进行了Rasch分析来检验量表的维度、评级类别、项目契合度、可靠性指标、局部项目独立性和差异项目功能。结果研究人群包括115例患者。POSAS的10个回答选项出现故障,因此被崩溃,形成一个简洁的五级评定量表,有助于提高测量精度。之后,两个分量表的单维性得到了证实。然后,通过项目拟合Rasch模型,验证了POSAS v2.0的内部结构效度。信度指标高(≥0.80)。没有发现与年龄或性别有关的显著差异项目功能。结论:本研究证明了简化的rasch版本的患者和观察者疤痕评估量表(POSAS v2.1)在术后线性疤痕患者中具有良好的心理测量特性,并为未来改进该工具提供了见解。
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引用次数: 9
Preliminary Results Supporting the Bacterial Hypothesis in Red Breast Syndrome following Postmastectomy Acellular Dermal Matrix- and Implant-Based Reconstructions. 初步结果支持乳房切除术后脱细胞真皮基质和植入物重建后红乳综合征的细菌假说。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006227
M. Danino, A. El Khatib, O. Doucet, Lan Dao, J. Efanov, J. Bou-Merhi, M. Iliescu-nelea
Acellular dermal matrices have become a mandatory tool in reconstructive breast surgery. Since their introduction, they have been considered to be nonreactive and nonimmunogenic scaffolds. However, some patients who undergo implant-based breast reconstruction with acellular dermal matrices develop postoperative cutaneous erythema overlying their matrices, a condition commonly referred to as red breast syndrome. The aim of this study was to gain a better understanding of this phenomenon. An analysis was conducted on consecutive patients who underwent acellular dermal matrix- and implant-based breast reconstructions and developed red breast syndrome that was treated surgically between April of 2017 and June of 2018 at the authors' institution. During surgery, 1-cm specimens of acellular dermal matrix were sampled and analyzed by scanning electron microscopy. Observations were charted to score and record the presence and thickness of biofilm, and for identification of bacteria. These measurements were performed using Adobe Photoshop CS6 Extended software. Six postmastectomy breast reconstruction patients were included, all with AlloDerm Ready-to-Use-based reconstructions. All specimens were colonized by various bacteria ranging from Gram-negative bacilli to Gram-positive microorganisms. Biofilm was present in all studied specimens. The cause of skin erythema overlying acellular dermal matrix grafts, and the so-called red breast syndrome, may be related to contamination with various bacteria. Although contamination was omnipresent in analyzed samples, its clinical significance is variable. Even if acellular dermal matrix-based reconstructions are salvaged, this could come at the price of chronic local inflammation.
脱细胞真皮基质已成为乳房重建手术的必备工具。自引入以来,它们一直被认为是无反应性和无免疫原性的支架。然而,一些使用脱细胞真皮基质进行乳房再造术的患者术后会在基质上出现皮肤红斑,这种情况通常被称为红乳综合征。这项研究的目的是为了更好地理解这一现象。对2017年4月至2018年6月期间在作者所在机构接受脱细胞真皮基质和假体乳房重建并出现红乳综合征的连续患者进行了分析。术中取1 cm脱细胞真皮基质标本进行扫描电镜分析。观察结果被绘制成图表,以记录生物膜的存在和厚度,并用于识别细菌。这些测量是使用Adobe Photoshop CS6 Extended软件进行的。包括6例乳房切除术后乳房重建患者,均采用AlloDerm即用型重建。所有标本均被革兰氏阴性杆菌和革兰氏阳性微生物等多种细菌定植。所有研究标本中均存在生物膜。皮肤红斑覆盖脱细胞真皮基质移植物的原因,所谓的红乳综合征,可能与各种细菌污染有关。虽然污染是无处不在的分析样本,其临床意义是可变的。即使基于脱细胞真皮基质的重建被挽救,这也可能以局部慢性炎症为代价。
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引用次数: 11
Visualizing the pharmacological preconditioning effect of botulinum toxin A by the infrared thermography in a rat pedicled perforator island flap model. 用红外热成像技术观察A型肉毒毒素对大鼠带蒂穿支岛状皮瓣的药理预处理效果。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006251
Miao Chen, Xiucun Li, Zhenmin Jiang, Xu Gong
BACKGROUNDSurgical delay can improve flap viability, leading to vasodilation, neovascularization, and vessel reorganization. Experiments suggest similar positive effect of botulinum toxin A (BTX-A) on pedicled flaps' viability. However, whether it may convert the choke anastomoses into the true anastomoses and how to identify the optimal timing for flap transfer remains unclear.METHODSOne hundred and fifty-four Sprague-Dawley rats were divided into a control group, three saline injection groups, and three BTX-A injection groups defined by time of injection (2, 3, 4 weeks before flap harvest). A pedicled flap of 11×3 cm was marked on the unilateral dorsum of rat. Before flap harvest, the flap donors were assessed by the infrared thermal imaging, postmortem arteriography, immunohistochemical staining of CD 31 and ELISA. Flap survival areas percentage was measured on postoperative day 7.RESULTSIn the control group and saline groups, the infrared thermography showed three independent white hotspots interspaced by red zones over flaps, whereas it presented a continuous white band in the BTX-A groups. There was a significant increase in the flap survival area, flap surface temperatures, the numbers of identifiable vessels in the choke zones, microvascular density and vascular endothelial growth factor concentration in the BTX-A groups.CONCLUSIONSBTX-A can convert the choke anastomoses into the true anastomoses and its preconditioning effect cannot increase over time; it is appropriate to choose the timing point when the infrared thermal images show a continuous white band existing over flaps for flap transfer.
手术延迟可以提高皮瓣的生存能力,导致血管扩张、新生血管和血管重组。实验表明,肉毒毒素A (BTX-A)对带蒂皮瓣的存活率也有类似的积极作用。然而,能否将阻塞吻合术转化为真正的吻合术,以及如何确定皮瓣转移的最佳时机,目前尚不清楚。方法将154只Sprague-Dawley大鼠分为对照组、生理盐水注射组和BTX-A注射组,按注射时间(皮瓣收获前2、3、4周)划分。在大鼠单侧背上标记有11×3 cm的带蒂皮瓣。取瓣前,采用红外热成像、死后动脉造影、cd31免疫组化染色及ELISA对供体进行评价。术后第7天测定皮瓣存活面积百分比。结果对照组和生理盐水组的红外热像图显示皮瓣上有3个独立的白色热点,中间有红色带,而BTX-A组则呈连续的白色带。BTX-A组皮瓣存活面积、皮瓣表面温度、阻塞区可识别血管数量、微血管密度和血管内皮生长因子浓度均显著增加。结论sbtx - a能将阻塞型吻合口转化为真吻合口,且预处理效果不随时间增加而增加;选择红外热图像显示皮瓣上方存在连续白带的时间点进行皮瓣转移比较合适。
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引用次数: 13
Discussion: Analysis of the Visual Perception of Female Breast Aesthetics and Symmetry: An Eye-Tracking Study. 讨论:女性乳房美学与对称的视觉感知分析:一项眼动追踪研究。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006293
M. Nahabedian
www.PRSJournal.com 1267 I this study, the authors used eye-tracking technology to assess the gazing patterns of 100 laypersons that included 50 men and 50 women as they looked at digital images of eight different female breasts that included frontal, lateral, and oblique views.1 Each breast image was divided into several areas of interest that included the nippleareola complex, breast quadrants, neck, clavicular region, sternal region, and inframammary fold. The observers were told to assess breast aesthetics and symmetry on a scale ranging from 1 to 10. Eye-tracking technology was used for each participant; however, the true purpose of the eye tracking was not revealed until after the study was completed. The observers assessed each image for 30 seconds before going on to the next image. During this time interval, visual gaze data were accrued and included the duration of gaze and the number of times their gaze was directed at a particular area of interest. Findings included no difference in the mean duration of gaze for each image between the men and women, with a range of 21.21 to 22.08 seconds. The remainder of the 30 seconds was spent on blinking and saccadic eye movements. The authors found that, for both groups, the longest fixation duration and the highest fixation number were recorded for lower breast regions and the nipple-areola complex. I believe that this is a fascinating study for several reasons. First, it demonstrates that eye tracking can provide useful information during object analysis. Previous work has validated eye tracking based on oculomotor metrics including fixation frequency and duration, saccade variation, eye blink, and pupil diameter.2 Second, it demonstrates that men and women tend to focus on the same areas of the breast without gender disparity. It is not surprising that the nipple-areola complex had the highest gaze duration, as this is the focal point of the breast and usually the reference point for symmetry. Third, I applaud the authors for including the lay public as the principal subjects because this established a true baseline without inherent bias. Had the observers been plastic surgeons, the gaze patterns may have been different because of inherent bias as to the parameters that constitute an ideal breast. Finally, I believe that this study will be extremely useful moving forward as we try to better understand patient expectations in the preoperative setting. It is this point that I will further elaborate on. One of the most frustrating aspects of aesthetic and reconstructive breast surgery is performing an operation in which the plastic surgeon is happy with the result, but the patient is not. We all appreciate that “setting” patient expectations preoperatively is important; however, truly “understanding” patient expectations is critical. How a plastic surgeon sees the breast may be completely different than how a patient sees her breast. Having knowledge of this disparity preoperatively may serve as va
www.PRSJournal.com 1267在这项研究中,作者使用眼球追踪技术来评估100名外行人的凝视模式,其中包括50名男性和50名女性,当他们看到8个不同的女性乳房的数字图像时,包括正面,侧面和倾斜视图每张乳房图像被划分为几个感兴趣的区域,包括乳头乳晕复合体、乳房象限、颈部、锁骨区域、胸骨区域和乳下褶皱。观察人员被要求对乳房的美感和对称性进行打分,评分范围从1到10。对每个参与者使用眼动追踪技术;然而,眼动追踪的真正目的直到研究完成后才揭晓。在观看下一张图片之前,观察者用30秒的时间来评估每张图片。在这段时间间隔内,视觉凝视数据被累积起来,包括凝视的持续时间和他们凝视特定感兴趣区域的次数。研究发现,男性和女性对每张图片的平均注视时间没有差异,在21.21秒到22.08秒之间。剩下的30秒时间用于眨眼和跳眼运动。作者发现,在两组中,最长的固定时间和最高的固定次数记录在乳房下部区域和乳头乳晕复合体。我相信这是一项引人入胜的研究,原因如下。首先,它证明了眼动追踪可以在对象分析过程中提供有用的信息。先前的工作已经验证了基于眼球运动指标的眼动追踪,包括注视频率和持续时间、扫视变化、眨眼和瞳孔直径其次,它表明男性和女性倾向于关注乳房的相同区域,没有性别差异。这并不奇怪,乳头-乳晕复合体有最长的凝视时间,因为这是乳房的焦点,通常是对称的参考点。第三,我赞赏作者将非专业公众作为主要研究对象,因为这建立了一个没有固有偏见的真实基线。如果观察者是整形外科医生,他们的凝视模式可能会有所不同,因为他们对构成理想乳房的参数有固有的偏见。最后,我相信这项研究将非常有用,因为我们试图更好地了解术前患者的期望。这一点我将作进一步阐述。乳房美容和乳房再造手术中最令人沮丧的一个方面是,整形医生对手术结果很满意,但患者却不满意。我们都知道术前“设定”病人的期望是很重要的;然而,真正“理解”病人的期望是至关重要的。整形外科医生看待乳房的方式可能与患者看待乳房的方式完全不同。术前了解这种差异可以作为继续手术的验证,也可以提出“危险信号”,促使整形外科医生重新考虑手术策略或完全拒绝手术。研究表明,在乳房再造患者中,身体畸形障碍的发生率为17%,而在普通人群中,这一比例为2%如果有一种机制可以更准确地识别这些患者,就可以获得具体的见解,以帮助确保从患者和整形外科医生的角度理解和现实的期望。这项技术的未来应用可能是术前确定患有身体畸形障碍的患者。通过使用聚焦于自己乳房数字图像的眼球追踪技术,可以跟踪和分析感兴趣的特定区域。确切地知道病人乳房的哪个部位是重点
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引用次数: 3
Clockwise Rotation of the Occlusal Plane for Aesthetic Purposes by Double Jaw Surgery without Orthodontic Treatment. 不经正畸治疗的双颌手术的顺时针旋转合平面的美学目的。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006248
T. Lee, Sanghoon Park
The occlusal plane angle is an important factor in lateral facial aesthetics. Low occlusal plane facial profiles appear planar and long-faced, whereas high occlusal plane facial profiles are considered more attractive, especially in Asian regions. Clockwise rotation of the occlusal plane for truly aesthetic purposes can be accomplished with double jaw surgery, without need for orthodontic treatments. Patients with normal occlusion who desired to improve their lateral facial aesthetics were included in this study. A conventional Le Fort I osteotomy was followed by a sagittal split ramus osteotomy under general anesthesia. The movement of the maxillomandibular complex was determined in accord with a preoperative analysis. From 2015 to 2017, 43 patients with normal occlusion underwent double jaw surgery without orthodontic treatment. Whereas all patients were subjectively satisfied with the surgery, two underwent orthodontic treatment to correct mild occlusal discrepancies noticed after surgery. There were no delayed occlusal problems or relapses reported during the study. For patients who desired to improve their lateral facial aesthetics but had normal occlusion, orthognathic surgery without orthodontic treatment can be effective. Clockwise rotation of the occlusal plane by double jaw surgery without orthodontic treatment resulted in satisfactory aesthetic outcomes with stable and reliable long-term results. CLINICAL QUESTION/LEVEL OF EVIDENCE:: Therapeutic, IV.
咬合面角是影响侧脸美观的重要因素。低咬合面面部轮廓显得平面和长脸,而高咬合面面部轮廓被认为更具吸引力,特别是在亚洲地区。顺时针旋转的咬合平面真正美观的目的可以完成双颌手术,而不需要正畸治疗。希望改善侧面面部美观的正常咬合患者被纳入本研究。常规Le Fort I型截骨术后在全身麻醉下行矢状分叉支截骨术。上颌下颌复合体的运动与术前分析一致。2015年至2017年,43例正常咬合患者在未进行正畸治疗的情况下接受了双颌手术。所有患者主观上都对手术满意,其中2例接受了正畸治疗,以纠正术后发现的轻度咬合差异。在研究期间,没有迟发性咬合问题或复发报告。对于希望改善侧面面部美观但咬合正常的患者,不进行正畸治疗的正颌手术是有效的。双颌手术在不进行正畸治疗的情况下顺时针旋转咬合平面,获得了满意的美学效果,长期效果稳定可靠。临床问题/证据水平:治疗性,IV。
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引用次数: 8
The Efficacy of Platelet-Rich Plasma Dressing for Chronic Nonhealing Ulcers: A Meta-Analysis of 15 Randomized Controlled Trials. 富血小板血浆敷料治疗慢性不愈合溃疡的疗效:15项随机对照试验的荟萃分析
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006281
Yijun Xia, Jun Zhao, Juan Xie, Yang Lv, Dongsheng Cao
BACKGROUNDSeveral randomized controlled trials comparing platelet-rich plasma to standard wound care for chronic wounds have been published. Previous articles have revealed that the role of platelet-rich plasma in promoting chronic wound healing is uncertain. This quantitative meta-analysis was conducted to evaluate whether superior outcomes can be obtained by using platelet-rich plasma in nonhealing ulcers compared with traditional wound care.METHODSThe PubMed, EMBASE, EBSCO (Cumulative Index to Nursing and Allied Health Literature), and Cochrane databases were searched through November of 2018 for randomized controlled trials comparing platelet-rich plasma to standard wound care for chronic wounds. For binary outcome measures, we calculated the risk ratio. The continuous outcomes were expressed as the mean differences. Subgroup analyses were also performed according to the type of chronic ulcer.RESULTSOverall, 630 adult patients in 15 randomized controlled trials from 2000 to 2018 were included. The number of ulcers healed in the platelet-rich plasma group was higher than in the control group, and the difference was statistically significant (risk ratio, 1.26; 95 percent CI, 1.11 to 1.42; p = 0.0003). During the fourth week of follow-up, the number of ulcers healed in the platelet-rich plasma group was significantly greater than in the control group (risk ratio, 3.50; 95 percent CI, 1.80 to 6.81; p = 0.0002).CONCLUSIONSPlatelet-rich plasma is a valuable and safe treatment dressing for chronic nonhealing ulcers; it is simple to prepare and has remarkable effects. Further high-quality prospective studies are necessary to validate these results.CLINICAL QUESTION/LEVEL OF EVIDENCETherapeutic, II.
背景:一些比较富血小板血浆和标准伤口护理治疗慢性伤口的随机对照试验已经发表。以前的文章表明,富血小板血浆在促进慢性伤口愈合中的作用是不确定的。本定量荟萃分析旨在评估与传统伤口护理相比,富血小板血浆治疗未愈合溃疡是否能获得更好的结果。方法检索截至2018年11月的PubMed、EMBASE、EBSCO(护理和相关健康文献累积索引)和Cochrane数据库,比较富血小板血浆与标准伤口护理对慢性伤口的随机对照试验。对于二元结果测量,我们计算了风险比。连续结果表示为平均差异。根据慢性溃疡类型进行亚组分析。结果共纳入2000 - 2018年15项随机对照试验的630例成人患者。富血小板血浆组溃疡愈合数高于对照组,差异有统计学意义(危险比,1.26;95% CI, 1.11 ~ 1.42;P = 0.0003)。随访第四周,富血小板血浆组溃疡愈合数显著高于对照组(风险比3.50;95% CI, 1.80 ~ 6.81;P = 0.0002)。结论富血小板血浆是一种有价值且安全的治疗慢性不愈合溃疡敷料;该制剂制备简单,效果显著。需要进一步的高质量前瞻性研究来验证这些结果。临床问题/证据治疗水平2。
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引用次数: 21
The Cutting Edge of Headache Surgery: A Systematic Review on the Value of Extracranial Surgery in the Treatment of Chronic Headache. 头痛外科的前沿:颅外手术治疗慢性头痛的系统综述。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006270
Thijs Bink, L. Duraku, Ryan P. Ter Louw, J. Zuidam, I. Mathijssen, C. Driessen
BACKGROUNDMigraine is a debilitating neurologic condition, with a large socioeconomic impact. There is a subgroup of patients that does not adequately respond to pharmacologic management and may have underlying neuralgia. Surgical decompression of extracranial sensory nerves has been proposed as an alternative therapy. The aim of this article is to review the evidence for the surgical treatment of neuralgias.METHODSA systematic review was conducted to study the efficacy of decompression of extracranial sensory nerves as a treatment for neuralgia. Clinical studies were included that studied patients, aged 18 years or older, diagnosed with any definition of headache and were treated with extracranial nerve decompression surgery. Outcome parameters included intensity (on a 10-point scale), duration (in days), and frequency (of headaches per month).RESULTSThirty-eight articles were found describing extracranial nerve decompression in patients with headaches. Postoperative decrease in headache intensity ranged from 2 to 8.2, reduction of duration ranged from 0.04 to 1.04 days, and reduction in frequency ranged between 4 and 14.8 headaches per month. Total elimination of symptoms was achieved in 8.3 to 83 percent of cases. A detailed summary of the outcome of single-site decompression is described. Statistical pooling and therefore meta-analysis was not possible, because of articles having the same surgeon and an overlapping patient database.CONCLUSIONSNerve decompression surgery is an effective way of treating headaches in a specific population of patients with neuralgia. Although a meta-analysis of the current data was not possible, the extracranial decompression of peripheral head and neck sensory nerves has a high success rate.
背景:偏头痛是一种使人衰弱的神经系统疾病,具有很大的社会经济影响。有一小部分患者对药物治疗没有充分的反应,可能有潜在的神经痛。颅外感觉神经的手术减压已被提出作为一种替代疗法。本文的目的是回顾神经痛的手术治疗的证据。方法对颅外感觉神经减压术治疗神经痛的疗效进行系统评价。临床研究包括年龄在18岁或以上,诊断为任何定义的头痛并接受颅外神经减压手术治疗的患者。结果参数包括强度(10分制)、持续时间(以天为单位)和频率(每月头痛)。结果共发现38篇描述头痛患者颅外神经减压的文章。术后头痛强度减少2 - 8.2天,持续时间减少0.04 - 1.04天,每月头痛次数减少4 - 14.8次。8.3%至83%的病例完全消除了症状。详细总结了单部位减压的结果。统计汇集和荟萃分析是不可能的,因为文章有相同的外科医生和重叠的患者数据库。结论神经减压手术是治疗特定人群神经痛患者头痛的有效方法。虽然无法对当前数据进行荟萃分析,但颅外减压头颈部周围感觉神经的成功率很高。
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引用次数: 14
Contemporary Approaches to Postoperative Pain Management. 术后疼痛处理的现代方法。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006268
A. Murphy, S. Haykal, D. Lalonde, T. Zhong
LEARNING OBJECTIVESAfter reading this article, the participant should be able to: 1. Describe the fundamental concepts of multimodal analgesia techniques and how they target pain pathophysiology. 2. Effectively educate patients on postoperative pain and safe opioid use. 3. Develop and implement a multimodal postoperative analgesia regimen.SUMMARYFor many years, opioids were the cornerstone of postoperative pain control, contributing to what has become a significant public health concern. This article discusses contemporary approaches to multimodal, opioid-sparing postoperative pain management in the plastic surgical patient.
学习目标阅读本文后,参与者应该能够:1。描述多模态镇痛技术的基本概念以及它们如何针对疼痛病理生理。2. 有效教育患者术后疼痛和安全使用阿片类药物。3.制定和实施多模式术后镇痛方案。多年来,阿片类药物是术后疼痛控制的基石,已成为一个重大的公共卫生问题。本文讨论了多模式,阿片类药物在整形外科患者术后疼痛管理的当代方法。
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引用次数: 8
Surgical Approach and Periprocedural Outcomes by Race and Ethnicity of Children Undergoing Craniosynostosis Surgery. 儿童颅缝闭锁手术的手术入路和围手术期结果与种族和民族的关系。
Pub Date : 2019-12-01 DOI: 10.1097/PRS.0000000000006254
Erin R. Wallace, C. Birgfeld, M. Speltz, J. Starr, B. Collett
BACKGROUNDSurgical repair for craniosynostosis varies depending on the infant's age, location of suture fusion, and approach (e.g., open versus endoscopic). Existing data suggest possible racial and ethnic disparities in timely access to surgical care for craniosynostosis that may, in turn, be associated with surgical approach and perioperative outcomes. This study examined racial and ethnic variation in craniosynostosis operations by surgical approach and perioperative outcomes.METHODSData were collected by the 2013 to 2015 Pediatric National Surgical Quality Improvement Program. Patients aged younger than 24 months with diagnoses and procedure codes consistent with surgery for craniosynostosis were identified. Periprocedural characteristics and surgical approach (open, endoscopic/minimally invasive, or both) were examined descriptively, overall, and separately by race and ethnicity.RESULTSThe authors identified 1982 admissions. Mean age at surgery was 7.8 ± 4.7 months. Ninety-one percent of procedures were classified as open operations, 5.8 percent were endoscopic, and 3.4 percent were both open and endoscopic. Relative to white/non-Hispanic patients, Hispanic and nonwhite patients underwent surgery at older ages, experienced longer operative and anesthesia times, and were hospitalized longer. Hispanic patients had the highest rates of open operations.CONCLUSIONSThese data suggest that Hispanic and nonwhite patients tend to undergo craniosynostosis repair at older ages and to have lengthier operations than white/non-Hispanic patients. Although we were unable to examine the root cause(s) of these differences, delayed diagnosis is one factor that might result in surgery at an older age and more complex operations requiring open surgery. Prospective studies examining racial/ethnic disparities are needed to inform a comparison of outcomes associated with surgical approach.
颅缝闭合的手术修复取决于婴儿的年龄、缝合融合的位置和入路(例如,开放还是内窥镜)。现有数据表明,在及时获得颅缝闭锁手术护理方面可能存在种族和民族差异,这可能反过来与手术入路和围手术期结果有关。本研究通过手术入路和围手术期结果调查了颅缝闭锁手术的种族和民族差异。方法采用2013 - 2015年全国儿科外科质量改进项目收集数据。患者年龄小于24个月,诊断和程序代码与颅缝闭锁手术一致。对围手术期特征和手术入路(开放、内窥镜/微创或两者兼而有之)进行描述性、总体性和种族和民族性检查。结果作者确定了1982例入院病例。平均手术年龄为7.8±4.7个月。91%的手术被归类为开放手术,5.8%是内窥镜手术,3.4%是开放和内窥镜手术。与白人/非西班牙裔患者相比,西班牙裔和非白人患者接受手术的年龄更大,手术和麻醉时间更长,住院时间更长。西班牙裔患者的开放性手术率最高。结论:这些数据表明,西班牙裔和非白人患者比白人/非西班牙裔患者更倾向于在年龄较大时进行颅缝闭合修复,并且手术时间更长。虽然我们无法检查这些差异的根本原因,但延迟诊断是可能导致老年手术和更复杂的手术需要开放手术的一个因素。需要对种族/民族差异进行前瞻性研究,以比较手术入路相关的结果。
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引用次数: 22
期刊
Plastic & Reconstructive Surgery
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