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Storage of plasma-derived exosomes: evaluation of anticoagulant use and preserving temperatures 血浆外泌体的储存:评估抗凝剂的使用和保存温度
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-04-17 DOI: 10.1080/09537104.2024.2337255
Caiting Yang, Jie Han, Hai Liu, Yuyu He, Zhenhua Zhang, Xiaochun Liu, Farooq Waqas, Lizhong Zhang, Huiping Duan, Jing He, Li Dong
Exosomes carry large cargo of proteins, lipids, and nucleic acids, serving as versatile biomarkers for disease diagnosis and vehicles for drug delivery. However, up to date, no well recognized stan...
外泌体携带大量蛋白质、脂质和核酸,是疾病诊断的多功能生物标记物和药物输送的载体。然而,到目前为止,还没有公认的外泌体检测标准。
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引用次数: 0
Activation of AMPK in platelets promotes the production of offspring 激活血小板中的 AMPK 可促进后代的产生
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-04-17 DOI: 10.1080/09537104.2024.2334701
Tong Zhang, Mengnan Yang, Shujun Li, Rong Yan, Kesheng Dai
Platelets are terminally differentiated anucleated cells, but they still have cell-like functions and can even produce progeny platelets. However, the mechanism of platelet sprouting has not been e...
血小板是终末分化的有核细胞,但仍具有类似细胞的功能,甚至可以产生后代血小板。然而,血小板萌发的机制还没有被证实。
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引用次数: 0
The bile acid receptor TGR5 inhibits platelet activation and thrombus formation 胆汁酸受体 TGR5 可抑制血小板活化和血栓形成
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-04-11 DOI: 10.1080/09537104.2024.2322733
Friedrich Reusswig, Maria Reich, Leonard Wienands, Diran Herebian, Verena Keitel-Anselmino, Margitta Elvers
Liver failure and cirrhosis are characterized by abnormal hemostasis with aberrant platelet activation. In particular, the consequences of cholestatic liver disease and molecular mechanisms, includ...
肝功能衰竭和肝硬化的特点是止血异常和血小板活化异常。特别是胆汁淤积性肝病的后果和分子机制,包括...
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引用次数: 0
The natural anticoagulant protein S; hemostatic functions and deficiency 天然抗凝血蛋白 S;止血功能和缺乏症
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-04-11 DOI: 10.1080/09537104.2024.2337907
Fahad S. Alshehri, Abdullah A. Bashmeil, Ibrahim A. Alamar, Sarah K. Alouda
Protein S (PS) is a vital endogenous anticoagulant. It plays a crucial role in regulating coagulation by acting as a cofactor for the activated protein C (APC) and tissue factor pathway inhibitor (...
蛋白 S(PS)是一种重要的内源性抗凝剂。它是活化蛋白 C(APC)和组织因子通路抑制因子(PS)的辅助因子,在调节凝血过程中起着至关重要的作用。
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引用次数: 0
Correlations among different platelet aggregation pathways in a group of healthy volunteers 一组健康志愿者不同血小板聚集途径之间的相关性
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-04-11 DOI: 10.1080/09537104.2024.2336093
Alejandro Carazo, Marcel Hrubša, Lukáš Konečný, Catherine Gunaseelan, Jaka Fadraersada, Pavel Skořepa, Markéta Paclíková, František Musil, Jana Karlíčková, Lenka Javorská, Kateřina Matoušová, Lenka Kujovská Krčmová, Alena Šmahelová, Vladimír Blaha, Přemysl Mladenka
Platelet aggregation is a complicated process mediated by different signaling pathways. As the process is highly complex and apparently redundant, the relationships between these pathways are not y...
血小板聚集是一个由不同信号通路介导的复杂过程。由于这一过程高度复杂且明显冗余,这些途径之间的关系并不清楚。
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引用次数: 0
Utility of VerifyNow to assess the immediate pharmacodynamic response of chewed and swallowed aspirin: comparison with aggregometry VerifyNow 用于评估咀嚼和吞咽阿司匹林的即时药效学反应:与聚集测定法的比较
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2024-01-03 DOI: 10.1080/09537104.2023.2298352
Kevin P. Bliden, Parshotam Kundan, Danielle Kraft, Rueshil Parekh, Sahib Singh, Aravind D. Babu, Anika P. Shah, Udaya S. Tantry, Paul A. Gurbel
VerifyNow (VN) test is a less laborious method to assess pharmacodynamics (PD) compared to light transmittance aggregometry (LTA). VN assay has not been used to study the immediate PD effects of ac...
与透光率聚集测定法(LTA)相比,VerifyNow(VN)试验是一种评估药效学(PD)的省力方法。VN 试验还没有被用于研究急性毒性反应的直接药效学效应。
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引用次数: 0
A case-control study of bleeding risk in children with 22q11.2 deletion syndrome undergoing cardiac surgery 关于 22q11.2 缺失综合征患儿接受心脏手术时出血风险的病例对照研究
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2023-12-15 DOI: 10.1080/09537104.2023.2290108
T. Blaine Crowley, Ian Campbell, Abinaya Arulselvan, David Friedman, Elaine H. Zackai, Tracy R. Geoffrion, Char Witmer, J. William Gaynor, Donna M. McDonald-McGinn, Michele P. Lambert
Previous research suggests that individuals with 22q11.2 deletion syndrome (DS) have an increased risk of bleeding following cardiac surgery. However, current guidelines for management of patients ...
以往的研究表明,22q11.2缺失综合征(DS)患者在心脏手术后出血的风险会增加。然而,目前的患者管理指南...
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引用次数: 0
Role of platelet count in a murine stasis model of deep vein thrombosis 血小板数量在小鼠深静脉血栓形成瘀滞模型中的作用
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2023-12-15 DOI: 10.1080/09537104.2023.2290916
Rick Mathews, Naly Setthavongsack, Anh Le-Cook, Andy Kaempf, Jennifer M Loftis, Randall L Woltjer, Christina U Lorentz, Alexey Revenko, Monica T Hinds, Khanh P Nguyen
Platelets are core components of thrombi but their effect on thrombus burden during deep vein thrombosis (DVT) has not been fully characterized. We examined the role of thrombopoietin-altered plate...
血小板是血栓的核心成分,但其对深静脉血栓形成(DVT)过程中血栓负荷的影响尚未完全定性。我们研究了血小板生成素改变对深静脉血栓形成的影响。
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引用次数: 0
The rapid change of shear rate gradient is beneficial to platelet activation 剪切率梯度的快速变化有利于血小板活化
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2023-12-15 DOI: 10.1080/09537104.2023.2288679
Tiancong Zhang, Ling Liu, Xiaojing Huang, Xuemei Gao, Xuanrong Huan, Cui He, Yuan Li
Fluid shear plays a key role in hemostasis and thrombosis, and the purpose of this study was to investigate the effect of shear gradient change rate (SGCR) on platelet reactivity and von Willebrand...
流体剪切力在止血和血栓形成中起着关键作用,本研究旨在探讨剪切梯度变化率(SGCR)对血小板反应性和von Willebrand的影响。
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引用次数: 0
Identification of apolipoprotein A-I as a target of platelet tyrosine kinases 鉴定作为血小板酪氨酸激酶靶点的载脂蛋白 A-I
IF 3.3 3区 医学 Q2 Medicine Pub Date : 2023-12-15 DOI: 10.1080/09537104.2023.2290921
Christine Föhrkolb, Katrin Vogel, Günter Lochnit, Peter Presek
Published in Platelets (Vol. 35, No. 1, 2024)
发表于《血小板》(第 35 卷第 1 期,2024 年)
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引用次数: 0
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