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Clinical characteristics and laboratory findings of patients with COVID-19 in Rasht, Iran 伊朗拉什特市COVID-19患者的临床特征和实验室结果
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.91
Tofigh Yaghubi Kalurazi, Vahid Shakoori, Sarah Nasiri, Ali Alavi Foumani, Ezat Hesni, L. Mahfoozi, Dorrin Aghajani, Zahra Gholamalipour, Roxana Ehsani, S. Mirzaei Dahka, N. Faraji
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引用次数: 0
Erratum: A survey of medical students' attitudes and practices towards narcotics and psychotropic drugs 校误:医学生对麻醉药品和精神药物的态度和做法的调查
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.103
Shahab Dastmardi, Alireza Kohansal Vajargah, Morteza Rahbar Taromsari, Hamid Mohammadi Kojidi, Ardalan Majidinia, Fariba Asgari Bozayeh, K. Ghaderi, Kourosh Delpasand
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引用次数: 0
New insight in severe acute respiratory syndrome coronavirus 2 consideration: Applied machine learning for nutrition quality, microbiome and microbial food poisoning concerns 在严重急性呼吸综合征冠状病毒2考虑的新见解:应用机器学习营养质量,微生物组和微生物食物中毒问题
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.55
Fatemeh Taslimi, Seyedeh Elham Hosseini Ezabadi, Maed Jabbari, Erfan Ghanbarzadeh, Mandana Ashkan, Farhad Akbari Afkhami, Amir Rigi, Mojtaba Hedayati Ch
Although almost two years have passed since the beginning of the coronavirus disease 2019 (COVID-19) pandemic in the world, there is still a threat to the health of people at risk and patients. Specialists in various sciences conduct various researches in order to eliminate or reduce the problems caused by this disease. Nutrition is one of the sciences that plays a very important supportive role in this regard. It is important for patients to pay attention to the potential of different diets in preventing or accelerating the healing process. The relationship between nutrition and microbiome regulation or the occurrence of food microbial poisoning is one of the factors that can directly or indirectly play a key role in the body's resilience to COVID-19. In this article, we introduce a link between nutrition, the microbiome, and the incidence of food microbial poisoning that may have great potential in preventing, treating COVID-19, or preventing deterioration in patients. In linking the components of this network, artificial intelligence (AI), machine learning (ML) and data mining (DM) can be important strategies and lead to the creation of a conceptual model called "Balance square", which we will introduce.
尽管2019冠状病毒病(COVID-19)在世界范围内开始流行已近两年,但对高危人群和患者的健康仍然构成威胁。各学科的专家进行各种研究,以消除或减少这种疾病引起的问题。营养学是其中一门科学,在这方面起着非常重要的支持作用。对于患者来说,注意不同饮食在预防或加速愈合过程中的潜力是很重要的。营养与微生物群调节或食物微生物中毒发生的关系,是直接或间接影响机体抗疫能力的关键因素之一。在本文中,我们介绍了营养、微生物组和食物微生物中毒发生率之间的联系,这可能在预防、治疗COVID-19或防止患者病情恶化方面具有巨大潜力。在连接这个网络的组成部分时,人工智能(AI),机器学习(ML)和数据挖掘(DM)可以是重要的策略,并导致创建一个称为“平衡平方”的概念模型,我们将介绍它。
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引用次数: 0
The effect of N2O gas on serum cobalamin and homocysteine in patients undergoing orthopedic surgery N2O气体对骨科手术患者血清钴胺素和同型半胱氨酸的影响
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.84
Amir Mohammad Azizi Kolachahi, Mahmood Khosravy, Aidin Badanara Marzdashty, M. Abedinzade
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引用次数: 0
The characterization of oxaliplatin-induced peripheral neuropathy using electromyography in gastrointestinal cancer patients 胃肠道肿瘤患者奥沙利铂诱导的周围神经病变的肌电特征
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.77
B. Bakhshayesh Eghbali, Sara Ramazani, H. Saeidi Saedi, Nazanin Rahman Amlash, E. Kazemnezhad leili, H. Hatamian, Cyrus Emir Alavi
{"title":"The characterization of oxaliplatin-induced peripheral neuropathy using\u0000 electromyography in gastrointestinal cancer patients","authors":"B. Bakhshayesh Eghbali, Sara Ramazani, H. Saeidi Saedi, Nazanin Rahman Amlash, E. Kazemnezhad leili, H. Hatamian, Cyrus Emir Alavi","doi":"10.52547/jcbior.3.2.77","DOIUrl":"https://doi.org/10.52547/jcbior.3.2.77","url":null,"abstract":"","PeriodicalId":204545,"journal":{"name":"Journal of Current Biomedical Reports","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133370451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of the effect of vaccination on transmissibility and pathogenicity of Omicron variant and its comparison with other SARS-CoV-2 variants 评价疫苗接种对Omicron变异的传播力和致病性的影响及其与其他SARS-CoV-2变异的比较
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.50
Neda Sinaei, Hamed Hekmatnezhad, Nafise Dani, Mona Keivan, Ashkan Roozitalab
The new variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has once again sounded the alarm on healthcare systems worldwide and has caused concern in some countries. This variant has been identified in South Africa and initially called B.1.1.529 and later renamed Omicron by the WHO. The transmissibility and immune evasion in the Omicron variant (B.1.1.529) is higher than the previous variants. Compared to the previous dominant variant, which was called the Delta variant, the Omicron variant has a very high transmission power but luckily, Omicron's symptoms are less serious. According to the WHO, the Omicron variant has the potential to re-infect people who already have other variants of SARS-CoV-2. Omicron contains at least 32 mutations in the spike protein also other proteins that are required for viral replication and it is twice the size of delta variant. Half of the mutations in this variant occur in the area of the virus through which they bind to the cells of the human body and cause infection. The Omicron variant likely developed in one person during chronic infection with an immune system deficiency (possibly untreated HIV/AIDS). It is possible that injecting a booster dose of existing vaccines and subsequently increasing antibody levels will provide adequate protection and an appropriate barrier against Omicron. The purpose of this article is to evaluate the Omicron variant and compare it with other SARS-CoV-2 variants and the effect of a booster dose in preventing disease progression.
新型严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)再次给全球卫生保健系统敲响了警钟,并在一些国家引起了关注。这种变异在南非被发现,最初被称为B.1.1.529,后来被世界卫生组织重新命名为Omicron。Omicron变体(B.1.1.529)的传播率和免疫逃避率高于以前的变体。与之前的显性变异(称为Delta变异)相比,欧米克隆变异具有非常高的传播能力,但幸运的是,欧米克隆的症状不那么严重。据世界卫生组织称,欧米克隆变体有可能再次感染已经感染了其他SARS-CoV-2变体的人。染色体组粒在刺突蛋白中包含至少32个突变还有病毒复制所需的其他蛋白质它的大小是变异的两倍。这种变异的一半突变发生在病毒与人体细胞结合并引起感染的区域。这种组粒变异可能发生在一名患有免疫系统缺陷(可能是未经治疗的艾滋病毒/艾滋病)的慢性感染患者身上。注射现有疫苗的加强剂并随后增加抗体水平可能会提供足够的保护和对欧米克隆的适当屏障。本文的目的是评估Omicron变体,并将其与其他SARS-CoV-2变体进行比较,以及加强剂量对预防疾病进展的影响。
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引用次数: 0
Symptomatic reinfection with COVID-19: A case-report study in Iran COVID-19症状性再感染:伊朗病例报告研究
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.98
Tofigh Yaghubi Kalurazi, Ehsan Amini-Salehi, Samira Rahimi-Shamami, Rahmat Poursmail, F. Joukar, Soheil Hassanipour, F. Mansour-Ghanaei
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引用次数: 1
Exosomal microRNAs released from tumor cells can play a role as reliable non-invasive biomarkers in the diagnosis and prognosis of breast cancer 肿瘤细胞释放的外泌体microRNAs可以作为可靠的非侵入性生物标志物在乳腺癌的诊断和预后中发挥作用
Pub Date : 2022-06-30 DOI: 10.52547/jcbior.3.2.62
Mahnaz Kiyanjam, Ghazal Soleymani, Fatemeh Khaloozadeh, F. Rouhollah
{"title":"Exosomal microRNAs released from tumor cells can play a role as reliable\u0000 non-invasive biomarkers in the diagnosis and prognosis of breast\u0000 cancer","authors":"Mahnaz Kiyanjam, Ghazal Soleymani, Fatemeh Khaloozadeh, F. Rouhollah","doi":"10.52547/jcbior.3.2.62","DOIUrl":"https://doi.org/10.52547/jcbior.3.2.62","url":null,"abstract":"","PeriodicalId":204545,"journal":{"name":"Journal of Current Biomedical Reports","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133014060","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Cost analysis of educational courses of medical students in Iran 伊朗医学生教育课程的成本分析
Pub Date : 2022-03-01 DOI: 10.52547/jcbior.3.1.43
S. Nikjoo, A. Rezapour, Torandokht Baluchnejad Mojarad, R. Jahangiri, Asma Rashki Kemak, Sajad Vahedi, Hiro Farabi
Estimating the cost of graduate courses can play an important role in deciding on the allocation of required resources. This study aimed to determine the cost of educational activities of graduate students in hospitals of medical universities in Iran . This study was performed in eight autonomous educational medical centers of Iran University of Medical Sciences, Tehran, Iran. After identifying the cost topics, the required information was collected through a semi-structured interview with the officials and students. Then, the amount of use of the graduate students from the cost headings was determined . The results identified that Doctor of Philosophy (PhD) students of microbiology with more than 950 United States dollar (USD) and PhD students of medical education with about 7 USD have created the highest and lowest costs, respectively. This study, for the first time, examined the educational costs of Iranian postgraduate students in the hospital. In conclusion, the results of this study indicated that the amount of the costs of different fields of graduate education in medical sciences is very different and it should be considered in the allocation of the resources.
估计研究生课程的成本对决定所需资源的分配起着重要的作用。本研究旨在确定伊朗医科大学医院研究生教育活动的成本。本研究在伊朗德黑兰伊朗医学大学的八个自治教育医学中心进行。在确定成本主题后,通过与官员和学生的半结构化访谈收集所需信息。然后,从成本标题中确定研究生的使用量。结果发现,微生物学博士研究生花费超过950美元,医学博士研究生花费约7美元,分别创造了最高和最低的成本。本研究首次考察了伊朗研究生在医院的教育费用。综上所述,本研究结果表明,医学研究生教育不同领域的成本金额差异很大,应在资源配置中加以考虑。
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引用次数: 0
Anti-bacterial effect of white tea extract on Streptococcus mutans and Streptococcus salivarius 白茶提取物对变形链球菌和唾液链球菌的抑菌作用
Pub Date : 2022-03-01 DOI: 10.52547/jcbior.3.1.27
N. Bashardoust, Shima Daryoush, Adel Ashouri, Parisa Rahimirad
Due to the increasing frequency of drug-resistant strains among different types of microorganisms, the finding of antimicrobial and antifungal compounds of natural substances, which certainly has fewer side effects, has long been of interest to researchers. Therefore, the aim of this investigation was to study the effect of white tea extract on reducing Streptococcus mutans and Streptococcus salivarius . White tea was prepared in powder form and then its hydroalcoholic extract of it was prepared. The antimicrobial effects of extracts on S. mutans and S. salivarius were performed using well diffusion and broth microdilution methods. All experiments were performed in triplet replications. Antibacterial susceptibility testing revealed that white tea extract at concentration of 500 µg/ml had a remarkable antibacterial activity against S. mutans , and S. salivarius with a zone of inhibition, 25±1 mm and 30±1, respectively. The minimum inhibitory concentration (MIC) values of the both tested strains were estimated 31.25 µg/ml. Moreover, the minimum bactericidal concentration (MBC) values of white tea extract were estimated 62.5 µg/ml against both streptococci. Considering the inhibitory power of the white tea extract on the gram-positive bacteria of S . salivarius and mutans , it can be concluded that this plant can be used in various industries, including the pharmaceutical and sanitary industry and it can also improve oral health as S. mutans and salvarius are the most important bacteria causing decays.
由于不同类型的微生物中耐药菌株的频率越来越高,寻找天然物质的抗菌和抗真菌化合物,其副作用肯定更小,一直是研究人员的兴趣所在。因此,本研究旨在研究白茶提取物对变形链球菌和唾液链球菌的抑制作用。以白茶为原料,制备白茶粉末,并提取其水醇提取物。采用孔扩散法和微量肉汤稀释法研究提取物对变形链球菌和唾液链球菌的抑菌作用。所有实验均以三组重复进行。抗菌药敏试验表明,浓度为500µg/ml的白茶提取物对变形链球菌和唾液链球菌具有显著的抑菌活性,抑菌区分别为25±1 mm和30±1 mm。两株菌株的最小抑菌浓度(MIC)均为31.25µg/ml。此外,白茶提取物对两种链球菌的最低杀菌浓度(MBC)值估计为62.5µg/ml。考虑白茶提取物对革兰氏阳性菌的抑制作用。由此可以得出结论,该植物可用于各个行业,包括制药和卫生行业,并且还可以改善口腔健康,因为变形链球菌和salvarius是最重要的引起腐烂的细菌。
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引用次数: 1
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Journal of Current Biomedical Reports
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