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[Acquired von Willebrand syndrome: case report and literature review]. [获得性冯-维勒布兰德综合征:病例报告和文献综述]。
Q4 Medicine Pub Date : 2024-09-01 DOI: 10.23785/PRAXIS.2024.08.007
Vincent Jendly, Nora Schwotzer, Jérôme Voegeli, Francisco J Gomez, Sébastien Kissling, Lorenzo Alberio

Introduction:

介绍:
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引用次数: 0
[Diagnosis and treatment of venous thrombosis]. [静脉血栓的诊断和治疗]。
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.002
Andrea Rosemann, Isabell Witzel, Matthias R Meyer, Giuseppe Pichierri, Thomas Rosemann, Oliver Senn

Introduction: The subject of this guideline from the Institute of Family Medicine at the University of Zurich (IHAMZ) is the management of venous thrombosis. The review summarizes the current evidence and recommendations from international guidelines (1-6). The IHAMZ-guidelines focus on primary care, they also provide guidance on the coordination of general and specialist medical care as well as on the transition between outpatient and hospital care taking into account the special features of the Swiss healthcare system. The guideline is devided in two parts. Part 1 discusses the diagnosis and treatment of deep vein thrombosis (DVT). A validated algorithm is recommended for the diagnostic process, which begins with the assessment of the clinical probability. With the inclusion of the D-dimer test, the need for subsequent imaging diagnostics can be reduced. The differences between the evaluation of an initial and recurrent DVT are shown and the indications and scope of evidence-based environmental diagnostics (thrombophilia and tumor search) are presented. All patients with DVT should receive anticoagulation (AC) for 3-6 months, as there is a high risk of recurrence with AC  3 months. The duration of the subsequent secondary prophylaxis depends on the presumed risk of recurrence on the one hand and the risk of bleeding on the other. Part 2 is dedicated to special thrombosis situations such as shoulder-arm vein thrombosis (SAVT), cancer-associated thrombosis (CAT) and superficial vein thrombosis (SVT). The article on hormone- and pregnancy-associated DVT, developed together with the Department of Gynecology at the University Hospital of Zurich, discusses the importance of hormonal contraception and menopausal hormone replacement therapy (HRT) as a thrombogenic risk factor as well as special features in the diagnosis and treatment of thrombosis in pregnancy.

导言:苏黎世大学(University of Zurich)家庭医学研究所(IHAMZ)制定的这份指南的主题是静脉血栓的治疗。该指南总结了当前的证据和国际指南(1-6)中的建议。苏黎世大学家庭医学研究所指南的重点是初级保健,同时还考虑到瑞士医疗保健系统的特殊性,就普通医疗保健和专科医疗保健的协调以及门诊和住院治疗之间的过渡提供指导。该指南分为两部分。第一部分讨论深静脉血栓(DVT)的诊断和治疗。该指南推荐了一种经过验证的诊断算法,首先要评估临床可能性。纳入 D-二聚体检测后,可减少对后续影像诊断的需求。本文介绍了初次深静脉血栓和复发性深静脉血栓评估之间的差异,并介绍了循证环境诊断(血栓性疾病和肿瘤搜索)的适应症和范围。所有深静脉血栓患者都应接受 3-6 个月的抗凝治疗(AC),因为 3 个月的抗凝治疗复发风险很高。后续二次预防的持续时间一方面取决于假定的复发风险,另一方面取决于出血风险。第二部分专门讨论特殊血栓形成情况,如肩臂静脉血栓形成(SAVT)、癌症相关血栓形成(CAT)和浅静脉血栓形成(SVT)。关于激素和妊娠相关深静脉血栓的文章是与苏黎世大学医院妇科共同编写的,其中讨论了激素避孕和绝经期激素替代疗法(HRT)作为血栓形成危险因素的重要性,以及妊娠期血栓诊断和治疗的特殊性。
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引用次数: 0
[Can we learn to die?] [我们能学会死亡吗? ]
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.003
Annina Seiler, Caroline Hertler, Sophia Rose Evstigneev, Markus Schettle, Steffen Eychmüller, Jan Gärtner, Sandra Eckstein, Cristian Camartin, Beat Müller, Mirjam Buschor-Bichsel, Tanja Fusi-Schmidhauser, Christa Hauswirth Siegenthaler, Brigitte Boothe, Simon Peng-Keller, David Blum

Introduction: The topic of death and the dying is a crucial aspect of patient care, especially for individuals with terminal illnesses. However, discussions about death and dying are often avoided during patient interactions. In this article, our aim is to explore the reasons behind our fear of death and dying and to assess the importance of addressing these issues in shaping and cultivating relationships with our patients and in our personal lives. We argue that being open to impermanence is a valuable tool in our work with patients and their families and should be integrated into conversations with them. Furthermore, discussions about death and dying should play a central role in medical and nursing education as well as professional development.

简介死亡和临终是病人护理的一个重要方面,尤其是对身患绝症的病人而言。然而,在与病人的交流中,有关死亡和临终的讨论往往被回避。在本文中,我们的目的是探讨我们对死亡和临终感到恐惧的原因,并评估在塑造和培养与病人的关系以及在我们的个人生活中解决这些问题的重要性。我们认为,对无常持开放态度是我们与病人及其家属合作的宝贵工具,应将其融入与他们的对话中。此外,关于死亡和临终的讨论应该在医学和护理教育以及职业发展中发挥核心作用。
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引用次数: 0
[Erythema and flu symptoms of a hunter with pre-existing conditions]. [一名猎人的红斑和流感症状]。
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.006
Pavla Tlapa, Reto Nüesch

Introduction: A hunter with a history of oncology, flu-like symptoms and ring-shaped erythema was treated with doxycycline in an outpatient setting on suspicion of a tick-borne disease. After obtaining a positive Francisella tularensis serology, antibiotic treatment was continued for a total of 21 days, followed by freedom of symptoms and falling CRP, but without prompt serological follow-up. In contrast to the previously described tularemia cases in Switzerland, the article shows less pronounced local finding without palpable lymphadenopathy.

导言:一名有肿瘤病史、流感样症状和环形红斑的猎人在门诊接受了强力霉素治疗,怀疑是蜱传疾病。在获得土拉菌病弗朗西斯菌血清学阳性结果后,抗生素治疗持续了 21 天,随后症状消失,CRP 下降,但没有及时进行血清学随访。与之前在瑞士描述的土拉菌病病例不同的是,该病例没有明显的局部症状,也没有可触及的淋巴结病。
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引用次数: 0
Blutdrucksenkung bei Patienten mit Schlaganfall in der Prähospitalisationsphase nicht wirksam. 中风患者在入院前阶段降压效果不佳。
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.001
Johann Steurer

Introduction:

介绍:
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引用次数: 0
[28-year-old male patient with headaches on the left side and facial pain]. [28岁男性患者,左侧头痛,面部疼痛]。
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.004
Sena Özkaratufan, Julia Velz, Luca Regli, Daniel Kirschenbaum, Diane Möller-Goede, Urs Eriksson

Introduction: A 28-year-old male suffers for two weeks from new-onset very severe headache located on his left temple radiating to his jaw. He also complains about left sided retroorbital pain and chewing aggravated symptoms. In addition, nausea and emesis in the mornings during the past six months were reported. Clinical examination revealed tender swelling over the left temple, but laboratory results showed no signs of inflammation, normal electrolytes, kidney and liver values. A CT-scan revealed a circumscriptive osteolytic lesion in the left os temporale.

导言:一名 28 岁的男性在两周前开始出现剧烈头痛,疼痛部位位于左太阳穴,并向下颌放射。他还抱怨左侧眶后疼痛,咀嚼时症状加重。此外,在过去的六个月里,他还出现了恶心和早晨呕吐的症状。临床检查发现左侧太阳穴有触痛性肿胀,但化验结果显示没有炎症迹象,电解质、肾脏和肝脏数值正常。CT扫描显示,左侧颞叶有一环状溶骨性病变。
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引用次数: 0
[Snakebite in Switzerland - a potentially life-threatening event?] [瑞士的蛇咬伤--可能危及生命吗?]
Q4 Medicine Pub Date : 2024-07-01 DOI: 10.23785/PRAXIS.2024.06.005
Jonas Micheroli, Markus Schneemann, Thomas Brack

Introduction: A 39-year-old healthy patient accidentally stepped barefoot on an adder and was then bitten into the foot. After initially only local complaints, severe systemic symptoms developed within 10-15 minutes with swelling of the lips and soft palate, recurrent vomiting, bradycardia, weakly palpable peripheral pulse, hypotension, dyspnea and intermittent somnolence. The potentially life-threatening consequences of this severe poisoning could be avoided by using adequate emergency measures and immediate intravenous administration of antivenin.

导言:一名 39 岁的健康患者不小心赤脚踩到一只金刚鹦鹉,然后被咬伤了脚。起初只是局部不适,但在 10-15 分钟内出现了严重的全身症状,包括嘴唇和软腭肿胀、反复呕吐、心动过缓、周围脉搏微弱、低血压、呼吸困难和间歇性嗜睡。如果采取适当的应急措施并立即静脉注射抗蛇毒血清,就可以避免这种严重中毒可能造成的危及生命的后果。
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引用次数: 0
[The CARE (CArdiovasculaR prEvention) Score - an instrument for recording the quality of care of cardiovascular risk patients in the GP practice]. [CARE(CArdiovasculaR prEvention)评分--全科医生诊所心血管风险患者护理质量记录工具]。
Q4 Medicine Pub Date : 2024-05-01 DOI: 10.23785/PRAXIS.2024.05.001
Thomas Rosemann, Isabella Sudano, Thomas F Lüscher, Oliver Strehle, Oliver Senn

Introduction: There is potential for improvement in the care of cardiovascular diseases in Switzerland, particularly when it comes to achieving target values defined in guidelines. Adherence scores such as the SGED score for diabetic care established in Switzerland can help to reduce the evidence-performance gap. The CARE score presented here is an adherence score that validly reflects the quality of care for patients with a cardiovascular risk using process and outcome indicators.

导言:瑞士在心血管疾病护理方面仍有改进的潜力,尤其是在实现指南中规定的目标值方面。瑞士针对糖尿病护理制定的 SGED 评分等依从性评分有助于缩小证据与绩效之间的差距。本文介绍的CARE评分是一种依从性评分,它利用过程和结果指标有效反映了心血管风险患者的护理质量。
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引用次数: 0
Cost Perception of Cardiological Procedures Among -Medical Students and Doctors in Switzerland. 瑞士医学生和医生对心脏病治疗费用的看法。
Q4 Medicine Pub Date : 2024-05-01 DOI: 10.23785/PRAXIS.2024.05.003
Alan Müller, Roger Melliger, Patric Biaggi, Luca Oechslin, Christophe Wyss

Introduction: Aims: The aim of the present study was to analyze the cost awareness of cardiological tests and procedures among medical students, residents and doctors in Switzerland and discuss trends in cost perception in health expenditures. Methods: Using an online questionnaire, participants (randomly recruited by mailing lists, messaging app or via direct contact) had to estimate the costs of the 13 predefined cardiological procedures services, diagnostic tests and procedures in Swiss Francs (CHF). Short technical descriptions of the procedures and tests were provided. Estimated costs were considered accurate if they were within ±25 % of the reimbursement rate. Participant groups were defined: medical students, residents, hospital-based physicians and cardiologists in private practice (practitioners). Results: A total of 939 participants (172 physicians and 767 medical students) were enrolled. The overall proportion of medical gestures estimated correctly within ±25% of the reimbursement rate ranged from 10 % (students) to 55 % in practitioners. Residents (26 %) and hospital-based physicians (38 %) performed intermediately. In general, the costs were overestimated. Conclusions: The level of cost knowledge of cardiological tests and procedures among medical students, residents and doctors in Switzerland is modest. In general, the costs were overestimated. Increasing experience seems to sharpen the accuracy of cost estimation. Overestimation of costs is potentially problematic: Either in systems of governmental defined global budget or systems with substantial out-of-pocket costs for patients, overestimated costs will result in more restrictive ordering than it would be appropriate and affordable for the individual patient.

简介:目的:本研究旨在分析瑞士医科学生、住院医师和医生对心脏病检查和治疗费用的认识,并讨论医疗支出中的费用趋势:目的:本研究旨在分析瑞士医科学生、住院医师和医生对心脏病检查和治疗费用的认识,并讨论医疗支出中费用认识的趋势。研究方法通过在线问卷调查,参与者(通过邮件列表、信息应用程序或直接联系等方式随机招募)必须以瑞士法郎(CHF)估算 13 项预定义心脏病治疗服务、诊断检测和手术的成本。我们提供了有关程序和检查的简短技术说明。如果估算费用在报销比例的±25%以内,则认为估算准确。参与群体包括医学生、住院医师、医院医生和私人执业的心脏病医生(从业者)。结果:共有 939 名参与者(172 名医生和 767 名医学生)参加了研究。在报销率的±25%范围内正确估计医疗手势的总比例从10%(学生)到55%(从业人员)不等。住院医生(26%)和医院医生(38%)的手势不准确。总的来说,费用被高估了。结论:瑞士医科学生、住院医师和医生对心脏病检查和手术的成本了解程度不高。总体而言,成本被高估了。经验的增加似乎会提高成本估算的准确性。高估成本可能会带来问题:无论是在政府确定的全球预算系统中,还是在患者需要自付大量费用的系统中,高估的费用都会导致下医嘱时受到更多限制,而这对患者个人来说是不合适的,也是负担不起的。
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引用次数: 0
[Hyperinflammatory immune response syndrome PIMS-TS]. [高炎症免疫反应综合征 PIMS-TS]。
Q4 Medicine Pub Date : 2024-05-01 DOI: 10.23785/PRAXIS.2024.05.006
Magdalena Müller-Groen, Gian Flury

Introduction: PIMS-TS is a rare hyperinflammatory immune response syndrome, usually occurring two to six weeks after SARS-CoV-2 infection, which mainly affects schoolchildren and is often associated with the need for intensive care (2). The most common clinical signs are high fever, gastrointestinal symptoms such as abdominal pain, vomiting and diarrhea, cardiovascular dysfunction (impaired LVEF, hypotension, shock) and neurological symptoms such as headache and encephalopathy (1, 2, 4). The definition criteria include various clinical and laboratory parameters, which vary slightly depending on the authors (4, 6, 7). With intensive care treatment with circulatory support and administration of methylprednisolone, mortality and long-term consequences remain low.

导言:PIMS-TS是一种罕见的高炎症免疫反应综合征,通常发生在感染SARS-CoV-2后的2至6周,主要影响学龄儿童,通常需要重症监护(2)。最常见的临床表现是高烧、腹痛、呕吐和腹泻等胃肠道症状、心血管功能障碍(LVEF 受损、低血压、休克)以及头痛和脑病等神经系统症状(1、2、4)。定义标准包括各种临床和实验室参数,因作者不同而略有差异(4、6、7)。通过循环支持和甲基强的松龙的重症监护治疗,死亡率和长期后果仍然很低。
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引用次数: 0
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Praxis
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