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"New" Psychiatric Emergencies Between Hospital and Territory. Survey Results on the Innovative Protocol Between the Emergency Department and Mental Health Center in Trento. 医院与地区之间的 "新 "精神病急诊。关于特伦托市急诊科与精神卫生中心之间创新协议的调查结果。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Wilma Angela Renata Di Napoli, Mjriam Sanò, Michela Marchiori, Davide Scordato

In 2022, psychiatric condition-related admissions constituted 3.2 per cent of all emergency room admissions in Italy, according to the Ministry of Health's latest mental health report. Psychiatric crises are an increasingly significant portion of emergency department (ED) visits nationwide, with around 1 in 8 visits involving mental health and substance use disorders. Patients facing psychiatric emergencies tend to experience longer lengths of stay and boarding times in the ED, along with higher admission rates compared to those with other medical conditions. Extended boarding times for psychiatric patients in the ED increase their vulnerability to adverse events, such as medication errors, the use of restraints, and assaults. Moreover, the prolonged boarding of psychiatric patients contributes to ED overcrowding, which negatively impacts all ED patients, leading to increased morbidity and mortality due to delays in treatment and preventable errors. One of the most effective strategies to counteract this phenomenon has been the choice of directing psychiatric emergencies that are deferrable or compatible with a territorial crisis management from the Trent ED to the Mental Health Center in the territory. This option, promoted through the application of experimental procedures that are currently in the process of being definitively ratified as official company procedures, has, first and foremost, numerous advantages for psychiatric users, who are received in less medicalized settings that are more attentive to the relational and psychological component, while still having suitable medical and nursing equipment. It also fosters continuity of care with the territorial therapeutic network, allows early interception of situations that are promptly taken care of by the territorial specialist center, and more easily offers treatment alternatives to hospitalization. This approach allows for the optimal utilisation of resources and expertise available at Mental Health Centres within the community, thereby preventing the overcrowding of hospital emergency departments.

根据卫生部最新发布的精神卫生报告,2022 年,与精神疾病相关的入院人数占意大利急诊室入院总人数的 3.2%。精神危机在全国急诊科(ED)就诊人数中所占的比例越来越大,大约每8次就诊中就有1次涉及精神健康和药物使用障碍。与患有其他疾病的患者相比,面临精神疾病紧急情况的患者在急诊室的住院时间和登机时间往往更长,入院率也更高。精神病患者在急诊室的住院时间延长会增加他们发生不良事件的可能性,如用药错误、使用限制措施和攻击行为。此外,精神科病人的长期寄宿会造成急诊室过度拥挤,从而对所有急诊室病人产生负面影响,导致治疗延误和可预防的错误,从而增加发病率和死亡率。应对这一现象的最有效策略之一,就是选择将可延期或符合地区危机管理的精神科急诊病人从特伦特急诊室转移到地区精神卫生中心。这一选择是通过采用试验性程序推广的,目前正处于最终批准成为公司正式程序的过程中。首先,这一选择对精神病患者有许多好处,因为他们可以在医疗程度较低的环境中接受治疗,这些环境更加关注关系和心理因素,同时还配备了适当的医疗和护理设备。此外,它还能促进与地区治疗网络的连续性,及早发现情况并由地区专科中心及时处理,并更容易提供住院治疗以外的其他治疗方法。这种方法可以充分利用社区内心理健康中心的资源和专业知识,从而避免医院急诊科人满为患。
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引用次数: 0
Nurses's Attitudes in Preventing Suicide: a Survey. 护士对预防自杀的态度:一项调查。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Antonella Litta, Francesca Bafaro, Chiara Cutrone, Vincenzo Favia, Francesco Pastore

Introduction: Nowadays, suicide represents a serious public health problem worldwide. Nurses can play a critical role in suicide prevention. Knowing risk factors and recognizing warning signs for suicide should be part of the professional background of any nurse training programs.

Methods: Our study presents the preliminary descriptive findings from an online survey in nursing staff operating in various areas (medical, surgical, critical and emergency) in the Apulia region. The survey aimed to assess the current knowledge, attitudes, behaviors and training needs of nurses regarding suicide prevention. We administered a questionnaire created with Google forms to a sample of subjects obtained through sampling a reasoned choice.

Results and conclusions: Our study highlighted the lack of perceived competence toward the suicidal patient and the need to implement specific training programs for nurses on the management of patients at risk of suicide. An adequate level of knowledge and competence regarding suicide prevention among healthcare professionals could significantly contribute to improving the quality of care provided to patients at risk for suicide, reducing the risk of suicidal events and improving the overall quality of the care pathway.

导言:如今,自杀已成为全球严重的公共卫生问题。护士在预防自杀方面可以发挥关键作用。了解自杀的风险因素和识别自杀的警示信号应成为任何护士培训课程的专业背景之一:我们的研究介绍了对阿普利亚地区各领域(内科、外科、重症和急诊)护理人员进行在线调查的初步描述性结果。调查旨在评估护士目前在预防自杀方面的知识、态度、行为和培训需求。我们使用谷歌表格制作了一份调查问卷,通过抽样合理选择的方式获得受试者样本:研究结果和结论:我们的研究突出表明,护士对有自杀倾向的病人缺乏认知能力,因此有必要对护士实施专门的培训计划,以管理有自杀风险的病人。如果医护人员对预防自杀有足够的认识和能力,将大大有助于提高为自杀风险患者提供的护理质量,降低自杀事件的风险,并提高护理路径的整体质量。
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引用次数: 0
Psychopathological and Therapeutic Trajectories of Inpatients Affected by Mixed States and Bipolar Spectrum Disorders. 受混合状态和双相情感障碍影响的住院病人的精神病理学和治疗轨迹。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Francesco Franza, Giovanna Celia, Wilma Angela Renata Di Napoli, Andreana Franza, Barbara Solomita, Francesca Pagnotta, Maurilio Giuseppe Maria Tavormina, Giuseppe Tavormina

In clinical practice, mental health professionals face diagnostic and therapeutic challenges daily. The diagnostic identification of mixed states allows the management of diagnostic and therapeutic trajectories appropriately. In our study, we evaluated 484 patients at a psychiatric rehabilitation center. The initial pre-admission diagnosis of the mixed state of 3.71% (at baseline) increased to 32.23%. The observation period was three years. The therapeutic efficacy of the pharmacological association of Antidepressants (Ads) or Second Generation Antipsychotics (SGAs) with a mood stabilizer (sodium valproate, lithium, lamotrigine, gabapentin, and pregabalin) was evaluated. An improvement in psychopathological symptoms was observed in different groups analyzed. The most significant differences were observed with the association SGAs + mood stabilizer [olanzapine + valproate sodium (p=0.005); risperidone + pregabalin (p=0.072)] and SSRIs + mood stabilizer [escitalopram + valproate sodium (p=0.005), vortioxetine + mood stabilizers (valproate or gabapentin). However, these are preliminary data and are under evaluation.

在临床实践中,精神卫生专业人员每天都要面对诊断和治疗方面的挑战。通过对混合状态的诊断识别,可以对诊断和治疗轨迹进行适当的管理。在我们的研究中,我们对一家精神康复中心的 484 名患者进行了评估。入院前最初诊断为混合状态的患者占 3.71%(基线),后来增加到 32.23%。观察期为三年。评估了抗抑郁药(ads)或第二代抗精神病药(SGAs)与情绪稳定剂(丙戊酸钠、锂、拉莫三嗪、加巴喷丁和普瑞巴林)联合使用的疗效。在分析的不同组别中,均观察到精神病理症状有所改善。在 SGAs + 情绪稳定剂[奥氮平 + 丙戊酸钠(p=0.005);利培酮 + 普瑞巴林(p=0.072)]和 SSRIs + 情绪稳定剂[艾司西酞普兰 + 丙戊酸钠(p=0.005),伏替西汀 + 情绪稳定剂(丙戊酸钠或加巴喷丁)]的组合中观察到了最明显的差异。不过,这些都是初步数据,正在评估中。
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引用次数: 0
Risk Assessment Suicidality Scale (RASS)-Based On-Line Calculator Targeting Early Prevention of Suicides in General Population: from COMET-G Study Results Towards Integration of the Screening Tool into Routine Clinical Practice. 基于风险评估自杀量表 (RASS) 的在线计算器,用于早期预防普通人群自杀:从 COMET-G 研究结果看将筛查工具纳入常规临床实践的前景。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Timur Syunyakov, Zarifjon Ashurov, Shakhnoza Magzumova, Darya Astafeva, Andrei Vlasov, Alexey Pavlichenko, Jelena Vrublevska, Xenia Gonda, Giuseppe Tavormina, Florence Thibaut, Paul Cumming, Avinash De Sousa, Konstantinos N Fountoulakis, Daria Smirnova

Background: Suicide is a major global health concern, particularly among young people. This study evaluates an online suicide risk calculator based on the Risk Assessment of Suicidality Scale (RASS), which is designed to enhance accessibility and early detection of suicide risk.

Methods: The study involved 444 participants who completed the RASS via an online calculator. Results were compared with data from the COMET-G study's Russian sample (n=7572). Descriptive statistics, correlation analysis, and two-way ANOVA were used to analyze the data.

Results: The mean age of participants was 22.71 years (SD=7.94). The mean total RASS standardized score was 837.7 (SD=297.8). There was a significant negative correlation between age and RASS scores (r=-0.463, p<0.0001). The online calculator sample showed significantly higher RASS scores compared to the COMET-G sample, with 71% of online users scoring above the 90th percentile of the COMET-G sample.

Conclusion: Our study demonstrated the advantage of the on-line suicidality risk calculator based on the RASS scale as a sensitive tool in detecting suicidal behaviours and measuring the severity of suicidality risks, offering a capability for broad reach and immediate assessment during clinical conversation between doctor and patient. Moreover, the RASS on-line psychometric instrument, when being freely distributed among the general population over internet sources, enabled to attract vulnerable groups of respondents with significantly higher suicidality risks. Future research should focus on integrating such tools into comprehensive suicide prevention programs and developing appropriate follow-up monitoring strategies for high risk-cases.

背景:自杀是全球关注的一大健康问题,尤其是在年轻人当中。本研究评估了基于自杀风险评估量表(RASS)的在线自杀风险计算器,该计算器旨在提高自杀风险的可及性和早期检测:研究涉及 444 名参与者,他们通过在线计算器完成了 RASS。研究结果与 COMET-G 研究的俄罗斯样本(7572 人)数据进行了比较。数据分析采用了描述性统计、相关性分析和双向方差分析:参与者的平均年龄为 22.71 岁(SD=7.94)。RASS 标准化总分的平均值为 837.7(标准差=297.8)。年龄与 RASS 分数之间存在明显的负相关(r=-0.463,p):我们的研究表明,基于 RASS 量表的在线自杀风险计算器在检测自杀行为和测量自杀风险严重程度方面具有灵敏的工具优势,能够在医生和患者的临床交谈中进行广泛而即时的评估。此外,当 RASS 在线心理测量工具通过互联网在普通人群中免费发放时,能够吸引自杀风险明显较高的弱势群体受访。未来的研究重点应是将此类工具纳入全面的自杀预防计划,并为高风险病例制定适当的后续监测策略。
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引用次数: 0
Assessing the Trajectory of Bipolar Disorder Effectively in Order to Treat Effectively. 有效评估躁郁症的发展轨迹,以便进行有效治疗。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Mark Agius, Anton Grech, Michaela Agius

Accurate diagnosis of mood disorders, particularly depression and bipolar disorder, is essential for effective treatment planning and patient management. This article emphasizes the need for systematic symptom assessment and longitudinal analysis in facilitating the precise diagnosis and planning appropriate treatment interventions. By meticulously evaluating the symptomatology and delineating the longitudinal trajectory of the illness, clinicians can distinguish between unipolar depression and bipolar disorder, and therefore optimise patient outcomes. The article describes the inherent complexities in diagnosing mood disorders. It describes the overlapping symptomatology and diagnostic challenges. Through a comprehensive review of literature and clinical insights, it argues for a structured approach to symptom assessment, focusing on both the current presentation and also retrospective evaluation of illness progression. By elucidating the longitudinal trajectory of the illness, including the presence of episodes of high mood suggestive of bipolar disorder, clinicians can differentiate between mood disorders accurately. The article discusses the implications of accurate diagnosis on treatment planning and patient prognosis. A precise diagnosis enables clinicians to plan treatment strategies to the specific needs of the individual, including pharmacotherapy, psychotherapy, or both. By addressing the underlying mechanisms and trajectory of the illness, clinicians can implement targeted interventions which reduce the risk of misdiagnosis and which optimize therapeutic outcomes.

情绪障碍(尤其是抑郁症和躁狂症)的准确诊断对于有效的治疗计划和患者管理至关重要。本文强调了系统性症状评估和纵向分析在促进精确诊断和规划适当治疗干预措施方面的必要性。通过对症状的细致评估和对疾病纵向轨迹的描述,临床医生可以区分单相抑郁症和双相情感障碍,从而优化患者的治疗效果。文章描述了情绪障碍诊断的内在复杂性。文章描述了重叠的症状和诊断难题。通过对文献和临床见解的全面回顾,文章主张采用结构化的症状评估方法,既要关注当前表现,也要对疾病进展进行回顾性评估。通过阐明疾病的纵向发展轨迹,包括是否出现暗示双相情感障碍的情绪高涨发作,临床医生可以准确地区分情绪障碍。文章讨论了准确诊断对治疗计划和患者预后的影响。准确的诊断使临床医生能够根据患者的具体需求制定治疗策略,包括药物治疗、心理治疗或两者兼用。通过了解疾病的潜在机制和发展轨迹,临床医生可以实施有针对性的干预措施,从而降低误诊风险并优化治疗效果。
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引用次数: 0
Management Strategies for Psychiatric Emergencies in a Community Setting. The Role of the Crisis Team at the Trento Mental Health Centre. 社区环境中的精神病突发事件管理策略。特伦托精神健康中心危机小组的作用。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Wilma Angela Renata Di Napoli, Davide Scordato, Benedetti Nicolas, Francesca Fasoli, Claudio Agostini

The Mental Health Service of Trento has consistently adopted a community-based, recovery-oriented approach. Adhering to these paradigms, and aiming to facilitate an intervention centred on the individual and their needs within their familial and social context, it is imperative to ensure a prompt and effective response to crises at the community level. Psychiatric emergencies present a significant challenge for health systems globally. Timely and appropriate management of these crises is crucial to prevent negative short and long-term outcomes. Providing such management in an extra-hospital setting, adaptable to the situational needs, can enable the individual to better achieve their recovery goals. Trento, with its dedicated Crisis service and the active involvement of Peer Support Specialists ("ESP" in italian), exemplifies how an integrated, multidisciplinary territorial approach that values the role of the socio-family context can enhance the outcomes of acute psychopathological crises and user engagement. This article discusses the organisation, advantages, and challenges compared to intra-hospital management, and the impact this intervention can have on public stigma regarding mental health.

特伦托心理健康服务机构一贯采取以社区为基础、以康复为导向的方法。秉承这些理念,并以个人及其家庭和社会背景下的需求为中心进行干预,必须确保在社区层面对危机做出迅速而有效的反应。在全球范围内,精神病突发事件是对医疗系统的重大挑战。及时、适当地处理这些危机对于防止短期和长期的不良后果至关重要。在院外环境中提供此类管理,并根据情况需要进行调整,可以使患者更好地实现康复目标。特伦托拥有专门的危机服务机构,并有同伴支持专家(意大利语为 "ESP")的积极参与,这充分体现了一种重视社会家庭背景作用的综合性多学科地区方法如何能够提高急性精神病理危机的治疗效果和用户参与度。本文讨论了与院内管理相比的组织、优势和挑战,以及这种干预措施对公众心理健康耻辱感的影响。
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引用次数: 0
Personal Dimensions in First Psychotic Episode Patients with Catatonia. 伴有紧张症的首次精神病发作患者的个人维度。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Natalia Zakharova, Lidia Bravve, Galina Mamedova, Maria Kaydan, Maria Skurinova, Dmitry Oshevsky

The study reports findings from an observational cross-sectional study involving patients experiencing their first psychotic episode with acute catatonia (n=82), compared to non-catatonic patients (n=74) and a group of healthy volunteers (n=47). Diagnostic procedures spanned two days: the first involved clinical interviews to assess psychosis structure and gather objective data (from relatives and medical records), while the second included psychometric evaluations using PANSS and BFCRS scales. Between these days, participants completed the Big Five Personality Factor Questionnaire (5PFQ) and Beck's Personality Beliefs Questionnaire (PBQ). Comparative analysis (H-test) across the three groups highlighted differences in the 5PFQ factor "expressiveness vs. practicality," predominantly influenced by the "sensitivity vs. insensitivity" parameter. Patients exhibiting catatonic symptoms demonstrated significantly lower scores compared to controls in this regard.

该研究报告了一项观察性横断面研究的结果,研究对象包括首次精神病发作的急性紧张症患者(82 人),与非紧张症患者(74 人)和一组健康志愿者(47 人)进行了比较。诊断过程持续了两天:第一天是临床访谈,以评估精神病的结构并收集客观数据(来自亲属和医疗记录);第二天是使用 PANSS 和 BFCRS 量表进行心理测量评估。在这两天之间,参与者还完成了大五人格因素问卷(5PFQ)和贝克人格信念问卷(PBQ)。三组之间的比较分析(H 检验)突出显示了 5PFQ 因素 "表现性与实用性 "的差异,这主要受到 "敏感性与不敏感性 "参数的影响。表现出紧张性症状的患者在这方面的得分明显低于对照组。
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引用次数: 0
Self-Harm Behavior and Suicidality Among Adolescents in Samara Region. 萨马拉地区青少年的自残行为和自杀倾向
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Mikhail Sheifer, Marina Pavlova, Tatiana Ashcheulova, Oxana Chigareva, Kseniya Bikbaeva, Daria Smirnova, Timur Syunyakov

Introduction: Self-harm behavior is a significant global concern, with Russia among the countries with high prevalence rates. Adolescents and young adults (15-29 years old) are particularly vulnerable, with suicide being the fourth leading cause of death in this age group. Our objective was to present statistics on suicidality and non-suicidal self-harm behavior (NSSH) among adolescents in the Samara region and to identify psychosocial differences between patients hospitalized for the first time and those hospitalized repeatedly.

Subjects and methods: This study is a retrospective chart analysis of adolescents hospitalized due to suicidal ideation or attempts in 2023. Data were collected from hospital records, comprising a diverse sample of adolescents.

Results: The sample included 76 adolescents, with a significant gender imbalance, as 84.2% were female. Chronic family conflicts presumably were the most influential factor, rather than family composition. Data on hereditary predisposition were subjective and presumably did not correlate with the number of hospitalizations. Fetal hypoxia was the only notable perinatal pathology. Self-harm behavior was more common in readmissions, while suicidal thoughts were present in similar proportions in both initial and repeat hospitalizations. The main reasons for self-harm behavior were the desire to gain control over life or to relieve emotional pain. Only 2.6% of cases were directly aimed at suicide.

Conclusions: Identified risk factors for suicidal behavior among adolescents included female gender, an unfavorable family environment, and NSSH, which, although not directly suicidal, increased the risk of future suicidal behavior. These factors should be considered in the diagnosis and prevention of suicidal behavior.

简介自残行为是全球关注的一个重要问题,俄罗斯是高发国家之一。青少年和年轻人(15-29 岁)尤其容易受到伤害,自杀是这个年龄组的第四大死因。我们的目的是提供萨马拉地区青少年自杀和非自杀性自残行为(NSSH)的统计数据,并找出首次住院患者和多次住院患者的社会心理差异:本研究对2023年因自杀意念或企图自杀而住院的青少年进行了回顾性病历分析。数据来自医院病历,由不同的青少年样本组成:该样本包括 76 名青少年,其中女性占 84.2%,性别严重失衡。长期的家庭矛盾可能是最有影响的因素,而不是家庭组成。有关遗传倾向的数据是主观的,可能与住院次数无关。胎儿缺氧是唯一值得注意的围产期病理现象。自残行为在再次入院中更为常见,而自杀念头在初次入院和再次入院中的比例相似。自残行为的主要原因是希望获得对生活的控制权或减轻情感上的痛苦。只有2.6%的病例直接以自杀为目的:已发现的青少年自杀行为风险因素包括女性性别、不利的家庭环境和NSSH,这些因素虽然不会直接导致自杀,但会增加未来自杀行为的风险。在诊断和预防自杀行为时应考虑这些因素。
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引用次数: 0
The Correlation Between Genetics and Suicidal Behaviors: a Challenge of Literature. 遗传与自杀行为之间的相关性:文献挑战。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Giada Juli, Rebecca Juli, Alfredo Juli, Luigi Juli

Suicide and suicidal behaviors seem to have a heritable component, and evidences from adoption, twins and families studies underline observations that greater familial suicidal behavior correlates with earlier onset and higher risk in offspring, supporting the presence of a genetic component. In this paper we report data from the literature, highlighting the scientific relevance of research in important topic as suicidal behaviours.

自杀和自杀行为似乎有遗传因素,领养、双胞胎和家庭研究的证据强调,家族中自杀行为较多的人,其后代的自杀行为发生较早,风险较高,这支持了遗传因素的存在。在本文中,我们报告了来自文献的数据,强调了自杀行为这一重要课题研究的科学意义。
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引用次数: 0
Incidence of Anxiety and Depression in Adult Patients with Chronic Discogenic Back Pain. 慢性椎间盘源性背痛成年患者的焦虑和抑郁发生率。
4区 医学 Q2 Medicine Pub Date : 2024-09-01
Regina Nasyrova, Maxim Novitsky, Natalia Shnayder, Vera Trefilova, Natalia Kuvshinova, Oksana Chigareva, Arseny Gayduk, Azamat Ashkhotov

Background: To analyze the results of domestic and foreign studies of the comorbidity of anxiety-depressive disorders and discogenic back pain in adult patients.

Subjects and methods: An analysis of Russian-language and foreign literature was carried out with a search depth of 5 years (2019-2024) in the following databases: PubMed, Springer, Wiley Online Library, Taylor & Francis Online, US National Library of Medicine National Institutes of Health, ScienceDirect and e-Library.

Results: Numerous studies have shown that depression and anxiety influence treatment outcomes in intervertebral disc degeneration (IVDD). Ineffective pharmacotherapy and inappropriate surgical interventions for depression and anxiety may significantly negatively affect the outcomes reported by patients with IVDD and chronic discogenic back pain. In addition, depression and anxiety have been reported to be risk factors for complications, chronic pain, and readmission after spinal surgery. Symptoms associated with mental stress, including depression and anxiety, were shown to be associated with changes in skeletal muscle tension symmetry in patients with IVDD, indicating that mental state is associated with muscle function. Therefore, it is useful for neurologists and neurosurgeons to identify anxiety and depressive disorders in patients with IVDD in order to promptly prescribe appropriate therapy for them.

Conclusion: Timely diagnosis of anxiety and depressive disorders and anxiety in patients with IVDD and chronic discogenic back pain requires an interdisciplinary approach with the participation of psychiatrists, neurologists and clinical pharmacologists, which is important for improving positive treatment outcomes and improving the quality of life of patients.

研究背景分析国内外关于成年患者焦虑抑郁障碍与椎间盘源性背痛合并症的研究结果:对俄语和国外文献进行分析,检索深度为 5 年(2019-2024 年),检索数据库如下:PubMed, Springer, Wiley Online Library, Taylor & Francis Online, US National Library of Medicine National Institutes of Health, ScienceDirect and e-Library.Results:大量研究表明,抑郁和焦虑会影响椎间盘变性(IVDD)的治疗效果。对抑郁和焦虑进行无效的药物治疗和不适当的手术干预可能会对 IVDD 和慢性椎间盘源性背痛患者的治疗效果产生严重的负面影响。此外,据报道,抑郁和焦虑是脊柱手术后并发症、慢性疼痛和再次入院的风险因素。与精神压力相关的症状(包括抑郁和焦虑)与 IVDD 患者骨骼肌张力对称性的变化相关,表明精神状态与肌肉功能相关。因此,神经内科和神经外科医生识别 IVDD 患者的焦虑和抑郁障碍,以便及时为他们开出合适的治疗处方,是非常有用的:及时诊断 IVDD 和慢性椎间盘源性背痛患者的焦虑和抑郁障碍以及焦虑,需要精神病学家、神经病学家和临床药理学家参与的跨学科方法,这对于提高积极的治疗效果和改善患者的生活质量非常重要。
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引用次数: 0
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Psychiatria Danubina
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