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Comparative evaluation of dentinal tubule occlusion by desensitizing agents after tooth bleaching: an in vitro study. 牙齿漂白后脱敏剂对牙本质小管闭塞的比较评价:一项体外研究。
IF 1.5 Pub Date : 2026-02-10 DOI: 10.5395/rde.2026.51.e8
Dimitrios Dionysopoulos, Petros Mourouzis, Spyros Papageorgiou, Kosmas Tolidis

Objectives: This study aimed to evaluate the efficacy of three commercially available desensitizing agents in occluding dentinal tubules, which may help reduce tooth sensitivity following a bleaching treatment.

Methods: Twenty healthy human third molars were utilized in this investigation. The samples were prepared by transversely sectioning 2.5 mm of the crowns to expose the dentin. They were initially treated with 15% ethylenediaminetetraacetic acid gel for 4 minutes, followed by application of Perfect Bleach (VOCO GmbH) bleaching agent (16% carbamide peroxide) for 2 hours. The samples were randomly allocated into four groups (n = 5), each receiving one of the following treatments: group 1: No treatment (control), group 2: treated with UltraEZ (Ultradent Products Inc.,), containing potassium nitrate and sodium fluoride, group 3: treated with Perfect Protect (VOCO GmbH), also containing potassium nitrate and sodium fluoride and group 4: treated with TheraSol Whitening & Sensitive (ABC Kinitron IKE), containing strontium acetate and sodium monofluorophosphate. Subsequently, the specimens were examined using scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy to evaluate dentin tubule occlusion.

Results: SEM observations showed no occlusion of dentin tubules in the control group, whereas groups 2 to 4 exhibited significant occlusion. The most effective treatment was Perfect Protect (p < 0.05), while UltraEZ and TheraSol Whitening & Sensitive demonstrated similar effectiveness, with no statistically significant difference between them (p > 0.05).

Conclusions: The tested desensitizing agents effectively occluded dentin tubules to a considerable extent. Differences in their effectiveness were attributed to variations in their formulations.

目的:本研究旨在评估三种市售脱敏剂在牙本质小管咬合中的效果,这可能有助于减少牙齿漂白治疗后的牙齿敏感性。方法:用20颗健康人第三磨牙进行研究。将牙冠横切2.5 mm,露出牙本质。首先用15%乙二胺四乙酸凝胶处理4分钟,然后用Perfect Bleach (VOCO GmbH)的漂白剂(16%过氧化脲)处理2小时。样本被随机分为四组(n = 5),每组接受以下处理之一:1组:无处理(对照),2组:用UltraEZ (Ultradent Products Inc.)治疗,含有硝酸钾和氟化钠,3组:用Perfect Protect (VOCO GmbH)治疗,也含有硝酸钾和氟化钠,4组:用TheraSol美白敏感(ABC Kinitron IKE)治疗,含有醋酸锶和单氟磷酸钠。随后,使用扫描电子显微镜(SEM)和能量色散x射线能谱检查标本,以评估牙本质小管闭塞。结果:扫描电镜观察,对照组未见牙本质小管堵塞,而2 ~ 4组牙本质小管堵塞明显。最有效的是Perfect Protect (p < 0.05),而UltraEZ和TheraSol美白&敏感的效果相似,两者之间差异无统计学意义(p < 0.05)。结论:所试脱敏剂对牙本质小管有一定程度的封闭作用。其疗效的差异归因于其配方的不同。
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引用次数: 0
Influence of adjacent restorative material and distance on the accuracy of inlay cavity impressions with intraoral scanner: an in vitro study. 邻近修复材料和距离对口腔内扫描仪嵌体腔印模准确性的影响:一项体外研究。
IF 1.5 Pub Date : 2026-01-23 DOI: 10.5395/rde.2026.51.e6
So-Yeon Lee, Sung-Ae Son, Jae-Hoon Kim, Deog-Gyu Seo, Jeong-Kil Park

Objectives: This study aimed to evaluate the influence of adjacent restorative material and interproximal distance on the accuracy of digital impressions of inlay cavities obtained using an intraoral scanner.

Methods: A disto-occlusal inlay cavity was prepared on a mandibular right first molar model, and digital scans were performed using a CEREC Primescan (Dentsply Sirona). The adjacent restorative materials used were Lava (3M ESPE), ENAMIC (VITA Zahnfabrik), Celtra Duo (Dentsply Sirona), and DMAX (DMAX INTERNATIONAL), and the interproximal distances were set to 0.6 mm, 0.8 mm, and 1.0 mm. The obtained scan data were analyzed using GOM Inspect software (GOM GmbH).

Results: Trueness, maximum positive and negative deviations, and precision were significantly influenced by both the adjacent restorative material and the interproximal distance, while their interaction showed a significant effect only on precision. Celtra Duo demonstrated the highest trueness, with mean deviation values decreasing from 7.8 μm at a 0.6 mm interproximal distance to 7.3 μm at 1.0 mm. ENAMIC showed the best precision, presenting mean deviations of 2.6 μm at 0.6 mm, 2.9 μm at 0.8 mm, and 2.4 μm at 1.0 mm. A narrow interproximal distance of 0.6 mm resulted in lower trueness, measured at 8.3 μm, and the highest precision deviation of 3.4 μm. In contrast, an interproximal distance of 1.0 mm yielded improved scan accuracy, with increased trueness and reduced precision variation.

Conclusions: Digital impression accuracy of inlay cavities was influenced by adjacent restorative material and interproximal distance, suggesting clinical consideration is needed in CAD/CAM workflows to optimize restoration fit.

目的:本研究旨在评估邻近修复材料和近端距离对口腔内扫描仪获得的嵌体腔数字印模准确性的影响。方法:在下颌右第一磨牙模型上制备游离咬合嵌体腔,并使用CEREC Primescan (Dentsply Sirona)进行数字扫描。邻近修复材料为Lava (3M ESPE)、ENAMIC (VITA Zahnfabrik)、Celtra Duo (Dentsply Sirona)和DMAX (DMAX INTERNATIONAL),近端间距分别设置为0.6 mm、0.8 mm和1.0 mm。利用GOM Inspect软件(GOM GmbH)对扫描数据进行分析。结果:邻近修复材料和近端间距离对正负偏差最大值、正负偏差最大值和精度均有显著影响,两者的交互作用仅对精度有显著影响。Celtra Duo显示出最高的准确性,平均偏差值从近端距离0.6 mm处的7.8 μm下降到1.0 mm处的7.3 μm。在0.6 mm处,平均偏差为2.6 μm;在0.8 mm处,平均偏差为2.9 μm;在1.0 mm处,平均偏差为2.4 μm。近端距离较窄(0.6 mm)导致准确率较低,测量值为8.3 μm,最高精度偏差为3.4 μm。相比之下,近端距离为1.0 mm可以提高扫描精度,提高准确性,减少精度变化。结论:邻近修复体材料和近端距离会影响嵌体空腔的数字印模精度,提示在CAD/CAM工作流程中需要临床考虑以优化修复体的贴合。
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引用次数: 0
Enhancing antimicrobial properties of a resin-based material via incorporation of a powdered phytotherapeutic extract: an in vitro experimental study. 通过掺入粉末状植物治疗提取物增强树脂基材料的抗菌性能:一项体外实验研究。
IF 1.5 Pub Date : 2026-01-20 DOI: 10.5395/rde.2026.51.e2
Rodolfo Xavier de Sousa-Lima, Maria Eduarda Lima do Nascimento Marinho, Janielly Cristina Costa da Silva, Moan Jéfter Fernandes Costa, Pedro Henrique Sette-de-Souza, Giana da Silveira Lima, Boniek Castillo Dutra Borges

Objectives: This study aimed to evaluate the degree of conversion (DC), immediate enamel bond strength (IEBS), antimicrobial activity, and release of the active principle of a resin-based material (RBM) enriched with the powdered Schinopsis brasiliensis (Braúna) stem antibacterial extract.

Methods: The RBM was enriched with 0, 1.25, 2.5, 5, 10, and 20 wt% powdered Braúna extract. The DC (n = 7) was assessed using micro-Raman spectroscopy. The IEBS (n = 7) was determined through the microshear test until failure, and failure modes were examined under a stereomicroscope. The antimicrobial activity (n = 15) was assessed by quantifying colony-forming units, and the release of the active principle was determined using ultra-high-performance liquid chromatography. One-way analysis of variance/Tukey and Kruskal-Wallis/Dunn tests were utilized to analyze the data (p < 0.05).

Results: Materials with 10 wt% and 20 wt% extract showed the lowest DC statistically. However, for IEBS, there were no statistically significant differences among the different groups. All materials released the active principle, but only those with 20 wt% and 10 wt% extract could inhibit biofilm formation similarly to 0.12% chlorhexidine.

Conclusions: Adding powdered Braúna extract between 10 wt% and 20 wt% is a promising alternative to provide an antimicrobial function to RBMs.

目的:本研究旨在评价巴西橡子(Braúna)茎干抗菌提取物粉末状富集树脂基材料(RBM)的转化度(DC)、即刻牙釉质结合强度(IEBS)、抗菌活性和释放活性原理。方法:分别用0、1.25、2.5、5、10、20 wt% Braúna粉末提取物对RBM进行富集。用微拉曼光谱测定DC (n = 7)。通过微剪切试验确定了IEBS (n = 7)直至破坏,并在体视显微镜下观察了破坏模式。采用定量菌落形成单位法测定其抑菌活性(n = 15),采用超高效液相色谱法测定其释放度。采用单因素方差分析/Tukey检验和Kruskal-Wallis/Dunn检验对数据进行分析(p < 0.05)。结果:10 wt%和20 wt%提取物的样品DC最低。而对于IEBS,不同组间差异无统计学意义。所有材料均释放出活性原理,但只有20% wt%和10% wt%提取物对生物膜形成的抑制作用与0.12%氯己定相似。结论:添加10 wt%至20 wt%的粉末状Braúna提取物是一种有前途的替代方法,可为rbm提供抗菌功能。
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引用次数: 0
Effect of combined application of premixed bioceramic paste and diode laser in vital pulp therapy: an immunohistochemical randomized controlled split-mouth in vivo animal experiment. 预混合生物陶瓷浆料与二极管激光联合应用在牙髓活体治疗中的效果:免疫组织化学随机对照口裂动物体内实验。
IF 1.5 Pub Date : 2026-01-20 DOI: 10.5395/rde.2026.51.e4
Mo'men A Salama, Dalia M Fayyad, Mohamed I Rabie, Manar A A Selim, Mahmoud F Ahmed

Objectives: This study aimed to evaluate the effect of premixed bioceramic paste (Well-Root PT; Vericom) compared to mineral trioxide aggregate (MTA) on the expression of the mineralization-related marker dentin sialoprotein (DSP) in dental pulp following direct pulp capping, with or without prior diode laser application.

Methods: Direct pulp exposures were performed in the upper and lower incisors of eight dogs (n = 96 teeth). Cavities (Class V) were created and received pulp capping with either Well-Root PT (n = 32), MTA (n = 32), or no capping material (Teflon disc only) (n = 32), with or without the application of a diode laser. Immunohistochemical analysis of DSP expression was conducted and quantified as the mean area percentage using ImageJ software at 2 and 8 weeks posttreatment.

Results: Both the Well-Root PT and MTA groups showed significantly increased DSP expression compared to the control group at both 2 and 8 weeks (p < 0.05). No significant difference in the mean area percentage of DSP expression was found between the Well-Root PT and MTA groups. The diode laser application did not produce a significant effect on DSP expression. Within-group comparison revealed a significant increase in DSP expression between the 2- and 8-week follow-up periods (p < 0.05).

Conclusions: Well-Root PT demonstrated comparable efficacy to MTA in promoting DSP expression, supporting its use as an effective direct pulp capping material. Diode laser application prior to capping had no effect on DSP expression in this experimental model.

目的:本研究旨在评估预混合生物陶瓷浆料(Well-Root PT; Vericom)与三氧化二矿骨料(MTA)对直接盖髓后牙本质涎蛋白(DSP)表达的影响,无论是否事先应用二极管激光。方法:对8只犬(96颗牙)的上、下门牙进行直接牙髓暴露。在有或没有应用二极管激光的情况下,使用Well-Root PT (n = 32)、MTA (n = 32)或不使用盖层材料(仅使用Teflon圆盘)(n = 32)进行牙髓盖层(V级)。在治疗后2周和8周用ImageJ软件对DSP表达进行免疫组化分析,并以平均面积百分比量化。结果:与对照组相比,Well-Root PT组和MTA组在2周和8周时DSP表达均显著升高(p < 0.05)。在Well-Root PT组和MTA组之间,DSP的平均表达面积百分比无显著差异。二极管激光的应用对DSP的表达没有显著影响。组内比较显示,随访2周和8周时DSP表达显著升高(p < 0.05)。结论:Well-Root PT在促进DSP表达方面表现出与MTA相当的功效,支持其作为有效的直接髓盖材料的使用。在该实验模型中,封盖前应用二极管激光对DSP的表达没有影响。
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引用次数: 0
Analysis of the reciprocating kinematics of the VDW Silver Reciproc, E-Connect Pro, Ecom, and Endopen endodontic motors: an in vitro experimental study. VDW Silver Reciproc、E-Connect Pro、Ecom和Endopen牙髓马达往复运动分析:体外实验研究。
IF 1.5 Pub Date : 2026-01-20 DOI: 10.5395/rde.2026.51.e5
Cristielly França, Juliana D Bronzato, Dieimes Braambati, Adriana de-Jesus-Soares, Carla C R B Félix, Michelle A N S Ferreira, Marcos Frozoni

Objectives: This study aimed to evaluate the actual parameters of four endodontic motors, each adjusted for reciprocating motion, and compare them to the manufacturers' declared values.

Methods: The motors used were the VDW Silver Reciproc (VDW GmbH), E-Connect Pro (MK Life), Ecom (Woodpecker), and Endopen (Schuster Woodpecker). A custom optical target was attached to the motor contra-angle, the movements were recorded with a high-resolution camera, and the images were analyzed. Engagement, disengagement, net angles, and speed for each operation cycle, duration of clockwise (CW) and counter-clockwise (CCW) movement, duration of standstill after CW and CCW movement, and the number of cycles to complete a full rotation were analyzed. The data were statistically analyzed at a significance level of 5%. The replicability of all reciprocal parameters analyzed was statistically different from that reported by the manufacturers.

Results: There was no statistically significant difference between the VDW Silver Reciproc, Ecom, and Endopen for the engagement angle. The E-Connect Pro was the least reliable at the 150°/30° settings for both angle parameters. There was no significant difference between the set and actual cycle net angles for the VDW Silver Reciproc (p = 0.493). While the actual values for the Ecom and E-Connect Pro were significantly higher than the set (p < 0.001), the actual values for the Endopen were significantly lower than the set (p < 0.001).

Conclusions: Experiments on four commercially available reciprocating endodontic motors revealed that the actual motor values differed significantly from the set values.

目的:本研究旨在评估四种牙髓马达的实际参数,每一种都调整为往复运动,并将其与制造商的声明值进行比较。方法:电机选用VDW Silver Reciproc (VDW GmbH)、E-Connect Pro (MK Life)、Ecom(啄木鸟)和Endopen (Schuster啄木鸟)。将定制的光学目标固定在电机对角上,用高分辨率摄像机记录运动,并对图像进行分析。分析了每个操作周期的啮合、脱离、净角、速度、顺时针(CW)和逆时针(CCW)运动的持续时间、顺时针(CW)和逆时针(CCW)运动后的静止时间以及完成一个完整旋转的周期数。数据以5%的显著性水平进行统计学分析。所分析的所有互反参数的可重复性与厂家报告的有统计学差异。结果:VDW - Silver Reciproc、Ecom、Endopen三种方法的夹持角差异无统计学意义。对于两个角度参数,E-Connect Pro在150°/30°设置时最不可靠。VDW银互惠的设定净角与实际周期净角无显著差异(p = 0.493)。虽然Ecom和E-Connect Pro的实际值显著高于set (p < 0.001),但Endopen的实际值显著低于set (p < 0.001)。结论:对4台市售往复式牙髓马达的实验表明,实际马达值与设定值有明显差异。
{"title":"Analysis of the reciprocating kinematics of the VDW Silver Reciproc, E-Connect Pro, Ecom, and Endopen endodontic motors: an in vitro experimental study.","authors":"Cristielly França, Juliana D Bronzato, Dieimes Braambati, Adriana de-Jesus-Soares, Carla C R B Félix, Michelle A N S Ferreira, Marcos Frozoni","doi":"10.5395/rde.2026.51.e5","DOIUrl":"https://doi.org/10.5395/rde.2026.51.e5","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to evaluate the actual parameters of four endodontic motors, each adjusted for reciprocating motion, and compare them to the manufacturers' declared values.</p><p><strong>Methods: </strong>The motors used were the VDW Silver Reciproc (VDW GmbH), E-Connect Pro (MK Life), Ecom (Woodpecker), and Endopen (Schuster Woodpecker). A custom optical target was attached to the motor contra-angle, the movements were recorded with a high-resolution camera, and the images were analyzed. Engagement, disengagement, net angles, and speed for each operation cycle, duration of clockwise (CW) and counter-clockwise (CCW) movement, duration of standstill after CW and CCW movement, and the number of cycles to complete a full rotation were analyzed. The data were statistically analyzed at a significance level of 5%. The replicability of all reciprocal parameters analyzed was statistically different from that reported by the manufacturers.</p><p><strong>Results: </strong>There was no statistically significant difference between the VDW Silver Reciproc, Ecom, and Endopen for the engagement angle. The E-Connect Pro was the least reliable at the 150°/30° settings for both angle parameters. There was no significant difference between the set and actual cycle net angles for the VDW Silver Reciproc (p = 0.493). While the actual values for the Ecom and E-Connect Pro were significantly higher than the set (p < 0.001), the actual values for the Endopen were significantly lower than the set (p < 0.001).</p><p><strong>Conclusions: </strong>Experiments on four commercially available reciprocating endodontic motors revealed that the actual motor values differed significantly from the set values.</p>","PeriodicalId":21102,"journal":{"name":"Restorative Dentistry & Endodontics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2026-01-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"146003557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Fifty-year follow-up of dens invaginatus treated by nonsurgical and surgical endodontic treatments: a case report. 非手术与手术治疗牙髓内陷50年随访1例。
IF 1.5 Pub Date : 2025-12-18 DOI: 10.5395/rde.2026.51.e1
Qais Arow, Eyal Rosen, Galit Sela, Shlomo Elbahary, Igor Tsesis

This case report presents a lateral maxillary incisor with dens invaginatus (DI) type IIIb that was treated both nonsurgically and surgically over 50 years. Treatment of teeth with DI can be challenging. Suggested options may include nonsurgical root canal treatment, endodontic surgery, or extraction. In this case report, a 13-year-old patient with a lateral maxillary incisor with DI type IIIb was treated by nonsurgical root canal treatment, modern endodontic surgery, and reoperation over the course of 50 years. There was complete healing at the last follow-up, 11 years after the reoperation. Correct diagnosis and proper treatment using modern endodontic techniques can enable teeth with DI to survive throughout the life span of the patient.

这个病例报告了上颌侧切牙与牙槽内凹(DI) IIIb型,治疗的非手术和手术超过50年。用DI治疗牙齿是很有挑战性的。建议的选择可能包括非手术根管治疗、牙髓手术或拔牙。在这个病例报告中,一个13岁的上颌侧切牙DI IIIb型患者在50年的时间里接受了非手术根管治疗、现代根管手术和再手术。再次手术后11年的最后一次随访完全愈合。正确的诊断和使用现代牙髓技术的适当治疗可以使DI的牙齿在患者的整个生命周期中存活。
{"title":"Fifty-year follow-up of dens invaginatus treated by nonsurgical and surgical endodontic treatments: a case report.","authors":"Qais Arow, Eyal Rosen, Galit Sela, Shlomo Elbahary, Igor Tsesis","doi":"10.5395/rde.2026.51.e1","DOIUrl":"https://doi.org/10.5395/rde.2026.51.e1","url":null,"abstract":"<p><p>This case report presents a lateral maxillary incisor with dens invaginatus (DI) type IIIb that was treated both nonsurgically and surgically over 50 years. Treatment of teeth with DI can be challenging. Suggested options may include nonsurgical root canal treatment, endodontic surgery, or extraction. In this case report, a 13-year-old patient with a lateral maxillary incisor with DI type IIIb was treated by nonsurgical root canal treatment, modern endodontic surgery, and reoperation over the course of 50 years. There was complete healing at the last follow-up, 11 years after the reoperation. Correct diagnosis and proper treatment using modern endodontic techniques can enable teeth with DI to survive throughout the life span of the patient.</p>","PeriodicalId":21102,"journal":{"name":"Restorative Dentistry & Endodontics","volume":" ","pages":""},"PeriodicalIF":1.5,"publicationDate":"2025-12-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145782700","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Difference in light transmittance and depth of cure of flowable composite depending on tooth thickness: an in vitro experimental study. 牙厚对流动复合材料透光率和固化深度影响的体外实验研究
IF 1.5 Pub Date : 2025-11-01 Epub Date: 2025-11-28 DOI: 10.5395/rde.2025.50.e39
Seong-Pyo Bae, Myung-Jin Lee, Kyung-San Min, Mi-Kyung Yu, Kwang-Won Lee

Objectives: This study aimed to quantify light attenuation through varying tooth thicknesses and its impact on the depth of cure of composite resin.

Methods: Twenty extracted premolars were used to create enamel-dentin discs that were sanded progressively in 0.5 mm increments from 2.5 mm to 0.5 mm. Light irradiance was measured with and without tooth specimens to evaluate light transmittance. Resin was cured beneath different thicknesses, and the depth of cure was assessed using the Vickers hardness test.

Results: The results demonstrated that light transmittance significantly decreased as tooth thickness increased (p < 0.01), leading to reduced resin polymerization. In the 2.0-mm and 2.5-mm tooth thickness groups, the depth of cure was significantly lower than in the control group without tooth specimens (p < 0.05).

Conclusions: Ultimately, for tooth structures exceeding 2 mm, self-cure or dual-cure resin polymerization is thought to be more efficient than light polymerization.

目的:研究不同牙厚对复合树脂固化深度的影响。方法:用20颗拔出的前磨牙制作牙釉质-牙本质盘,从2.5 mm到0.5 mm,以0.5 mm的增量逐步打磨。测量带牙和不带牙标本的光辐照度以评估光透射率。树脂在不同厚度下固化,用维氏硬度测试评估固化深度。结果:随着牙厚的增加,透光率显著降低(p < 0.01),导致树脂聚合减少。牙厚2.0 mm和2.5 mm组的修复深度明显低于无牙标本对照组(p < 0.05)。结论:最终,对于超过2mm的牙齿结构,自固化或双固化树脂聚合被认为比光聚合更有效。
{"title":"Difference in light transmittance and depth of cure of flowable composite depending on tooth thickness: an in vitro experimental study.","authors":"Seong-Pyo Bae, Myung-Jin Lee, Kyung-San Min, Mi-Kyung Yu, Kwang-Won Lee","doi":"10.5395/rde.2025.50.e39","DOIUrl":"10.5395/rde.2025.50.e39","url":null,"abstract":"<p><strong>Objectives: </strong>This study aimed to quantify light attenuation through varying tooth thicknesses and its impact on the depth of cure of composite resin.</p><p><strong>Methods: </strong>Twenty extracted premolars were used to create enamel-dentin discs that were sanded progressively in 0.5 mm increments from 2.5 mm to 0.5 mm. Light irradiance was measured with and without tooth specimens to evaluate light transmittance. Resin was cured beneath different thicknesses, and the depth of cure was assessed using the Vickers hardness test.</p><p><strong>Results: </strong>The results demonstrated that light transmittance significantly decreased as tooth thickness increased (p < 0.01), leading to reduced resin polymerization. In the 2.0-mm and 2.5-mm tooth thickness groups, the depth of cure was significantly lower than in the control group without tooth specimens (p < 0.05).</p><p><strong>Conclusions: </strong>Ultimately, for tooth structures exceeding 2 mm, self-cure or dual-cure resin polymerization is thought to be more efficient than light polymerization.</p>","PeriodicalId":21102,"journal":{"name":"Restorative Dentistry & Endodontics","volume":"50 4","pages":"e39"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707564/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Evaluation of platelet concentrates in regenerative endodontics: a systematic review and meta-analysis. 血小板浓缩物在再生牙髓学中的评价:系统回顾和荟萃分析。
IF 1.5 Pub Date : 2025-11-01 Epub Date: 2025-11-28 DOI: 10.5395/rde.2025.50.e38
Anna Tsiolaki, Dimitrios Theocharis, Nikolaos Tsitsipas, Anastasia Fardi, Konstantinos Kodonas

Objectives: The aim of this systematic review is to compare the effectiveness of advanced platelet concentrates as regenerative endodontic therapeutic alternatives to blood clot (BC) revascularization in immature permanent necrotic teeth.

Methods: Randomized controlled trials (RCTs) comparing regenerative endodontic therapies using platelet-rich plasma (PRP), platelet-rich fibrin (PRF), or platelet pellet (PP) with the BC revascularization approach in immature permanent necrotic teeth were systematically searched in PubMed, Scopus, Cochrane Library, and Web of Science until May 2025. Data was extracted and analyzed both qualitatively and quantitatively. Study quality was assessed using the Cochrane Risk of Bias tool. A meta-analysis was conducted using IBM SPSS software (version 29.0), with success rates expressed as risk ratios and 95% confidence intervals (CIs).

Results: The initial search yielded 4,917 studies. After removing duplicates and applying eligibility criteria, 15 RCTs were included. Meta-analysis indicated no significant difference in the risk ratio (RR), as the BC method has similar success rates with PRP (10 studies; RR = 1.01; 95% CI, 0.94-1.09; p = 0.76) and PRF (8 studies; RR = 0.98; 95% CI, 0.89-1.08; p = 0.65) at 12 months. The primary outcomes evaluated were based on clinical and radiographic success.

Conclusions: Current evidence suggests PRP, PRF, and BC are all effective in treating immature permanent necrotic teeth with similar success rates. However, further research is needed to assess long-term outcomes.

目的:本系统综述的目的是比较先进的血小板浓缩物作为再生根管治疗替代血凝块(BC)重建术治疗未成熟永久性坏死牙齿的有效性。方法:到2025年5月,系统检索PubMed、Scopus、Cochrane Library和Web of Science,比较使用富血小板血浆(PRP)、富血小板纤维蛋白(PRF)或血小板颗粒(PP)再生牙髓治疗未成熟永久性坏死牙齿的方法与BC血管重建方法的随机对照试验(rct)。提取数据并进行定性和定量分析。使用Cochrane偏倚风险工具评估研究质量。采用IBM SPSS软件(version 29.0)进行meta分析,成功率以风险比和95%置信区间(ci)表示。结果:最初的搜索产生了4917项研究。在去除重复项并应用资格标准后,纳入了15项随机对照试验。meta分析显示,在12个月时,BC方法与PRP(10项研究,RR = 1.01; 95% CI, 0.94-1.09; p = 0.76)和PRF(8项研究,RR = 0.98; 95% CI, 0.89-1.08; p = 0.65)的成功率相似,因此风险比(RR)无显著差异。评估的主要结果是基于临床和放射学的成功。结论:目前的证据表明,PRP、PRF和BC治疗未成熟永久性坏死牙均有效,成功率相似。然而,需要进一步的研究来评估长期结果。
{"title":"Evaluation of platelet concentrates in regenerative endodontics: a systematic review and meta-analysis.","authors":"Anna Tsiolaki, Dimitrios Theocharis, Nikolaos Tsitsipas, Anastasia Fardi, Konstantinos Kodonas","doi":"10.5395/rde.2025.50.e38","DOIUrl":"10.5395/rde.2025.50.e38","url":null,"abstract":"<p><strong>Objectives: </strong>The aim of this systematic review is to compare the effectiveness of advanced platelet concentrates as regenerative endodontic therapeutic alternatives to blood clot (BC) revascularization in immature permanent necrotic teeth.</p><p><strong>Methods: </strong>Randomized controlled trials (RCTs) comparing regenerative endodontic therapies using platelet-rich plasma (PRP), platelet-rich fibrin (PRF), or platelet pellet (PP) with the BC revascularization approach in immature permanent necrotic teeth were systematically searched in PubMed, Scopus, Cochrane Library, and Web of Science until May 2025. Data was extracted and analyzed both qualitatively and quantitatively. Study quality was assessed using the Cochrane Risk of Bias tool. A meta-analysis was conducted using IBM SPSS software (version 29.0), with success rates expressed as risk ratios and 95% confidence intervals (CIs).</p><p><strong>Results: </strong>The initial search yielded 4,917 studies. After removing duplicates and applying eligibility criteria, 15 RCTs were included. Meta-analysis indicated no significant difference in the risk ratio (RR), as the BC method has similar success rates with PRP (10 studies; RR = 1.01; 95% CI, 0.94-1.09; p = 0.76) and PRF (8 studies; RR = 0.98; 95% CI, 0.89-1.08; p = 0.65) at 12 months. The primary outcomes evaluated were based on clinical and radiographic success.</p><p><strong>Conclusions: </strong>Current evidence suggests PRP, PRF, and BC are all effective in treating immature permanent necrotic teeth with similar success rates. However, further research is needed to assess long-term outcomes.</p>","PeriodicalId":21102,"journal":{"name":"Restorative Dentistry & Endodontics","volume":"50 4","pages":"e38"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707569/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145669282","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Marginal adaptation of three root-end filling materials in cavities prepared with laser and ultrasonic tips: an in vitro comparative study. 三种根端填充材料在激光和超声尖端制备的牙槽中的边缘适应性:体外比较研究。
IF 1.5 Pub Date : 2025-11-01 Epub Date: 2025-09-09 DOI: 10.5395/rde.2025.50.e32
Busra Zengin, Seda Aydemir, Nicholas Paul Chandler

Objectives: This study evaluated the marginal adaptation of ProRoot MTA (Dentsply Tulsa Dental), Biodentine (Septodont), and TotalFill BC RRM (FKG) placed in root-end cavities prepared with ultrasonic or Er,Cr:YSGG laser tips, using scanning electron microscopy.

Methods: The canals of 90 extracted maxillary central incisors were prepared and obturated and their roots resected. Six groups of 15 specimens were allocated as follows: ultrasonic + ProRoot MTA, ultrasonic + Biodentine, ultrasonic + TotalFill, laser + ProRoot MTA, laser + Biodentine, and laser + TotalFill. Roots were sectioned longitudinally to expose the filling material. Apical and coronal micrographs were taken, and the greatest distance between dentin and filling material was measured. The total gap area was also calculated using further micrographs.

Results: Cavities prepared with the ultrasonic tips and filled with Biodentine showed significantly greater gap dimensions compared with TotalFill (p < 0.001) and ProRoot MTA (p = 0.007) in the apical region. The ultrasonic group showed significantly higher void values compared to the laser group for ProRoot MTA (p = 0.026), when comparing the total values of void. The Biodentine group was significantly higher than the TotalFill group in root-end cavities prepared with ultrasonic tips (p < 0.001). The Biodentine group was significantly higher than the ProRoot MTA group in root-end cavities prepared with the laser tip (p = 0.002).

Conclusions: Under the conditions of this study, it was determined that the root-end cavity preparation technique had an effect on the amount of gaps formed between the dentin and the three filling materials.

目的:本研究利用扫描电子显微镜评估了prooroot MTA (Dentsply Tulsa Dental)、Biodentine (septodon)和TotalFill BC RRM (FKG)在超声或Er,Cr:YSGG激光尖端制备的根端腔中的边缘适应性。方法:对90例拔除的上颌中切牙预备根管,封闭根管,切除根管。6组15例标本分配为:超声+ prooroot MTA、超声+ Biodentine、超声+ TotalFill、激光+ prooroot MTA、激光+ Biodentine、激光+ TotalFill。根纵向切片,露出充填材料。观察牙本质与充填材料之间的最大距离。还使用进一步的显微照片计算了总间隙面积。结果:与TotalFill (p < 0.001)和prooroot MTA (p = 0.007)相比,用超声针尖制备的牙槽在根尖区域的间隙尺寸明显增大。超声组prooroot MTA空洞值明显高于激光组(p = 0.026)。在超声针尖制备的根端牙槽中,Biodentine组明显高于TotalFill组(p < 0.001)。在激光尖端制备的根端腔中,Biodentine组明显高于prooroot MTA组(p = 0.002)。结论:在本研究条件下,确定根端空腔制备技术对牙本质与三种充填材料之间形成的间隙数量有影响。
{"title":"Marginal adaptation of three root-end filling materials in cavities prepared with laser and ultrasonic tips: an in vitro comparative study.","authors":"Busra Zengin, Seda Aydemir, Nicholas Paul Chandler","doi":"10.5395/rde.2025.50.e32","DOIUrl":"10.5395/rde.2025.50.e32","url":null,"abstract":"<p><strong>Objectives: </strong>This study evaluated the marginal adaptation of ProRoot MTA (Dentsply Tulsa Dental), Biodentine (Septodont), and TotalFill BC RRM (FKG) placed in root-end cavities prepared with ultrasonic or Er,Cr:YSGG laser tips, using scanning electron microscopy.</p><p><strong>Methods: </strong>The canals of 90 extracted maxillary central incisors were prepared and obturated and their roots resected. Six groups of 15 specimens were allocated as follows: ultrasonic + ProRoot MTA, ultrasonic + Biodentine, ultrasonic + TotalFill, laser + ProRoot MTA, laser + Biodentine, and laser + TotalFill. Roots were sectioned longitudinally to expose the filling material. Apical and coronal micrographs were taken, and the greatest distance between dentin and filling material was measured. The total gap area was also calculated using further micrographs.</p><p><strong>Results: </strong>Cavities prepared with the ultrasonic tips and filled with Biodentine showed significantly greater gap dimensions compared with TotalFill (p < 0.001) and ProRoot MTA (p = 0.007) in the apical region. The ultrasonic group showed significantly higher void values compared to the laser group for ProRoot MTA (p = 0.026), when comparing the total values of void. The Biodentine group was significantly higher than the TotalFill group in root-end cavities prepared with ultrasonic tips (p < 0.001). The Biodentine group was significantly higher than the ProRoot MTA group in root-end cavities prepared with the laser tip (p = 0.002).</p><p><strong>Conclusions: </strong>Under the conditions of this study, it was determined that the root-end cavity preparation technique had an effect on the amount of gaps formed between the dentin and the three filling materials.</p>","PeriodicalId":21102,"journal":{"name":"Restorative Dentistry & Endodontics","volume":" ","pages":"e32"},"PeriodicalIF":1.5,"publicationDate":"2025-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12707562/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145024131","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Phase transformation temperatures influence the reduction ratio of fatigue resistance of nickel-titanium reciprocating files at body temperature: an in vitro experimental study. 相变温度对镍钛往复锉在体温下抗疲劳降低率的影响:体外实验研究。
IF 1.5 Pub Date : 2025-11-01 Epub Date: 2025-11-05 DOI: 10.5395/rde.2025.50.e35
Walid Nehme, Alfred Naaman, Lola Pedèches, Sylvie Lê, Marie Georgelin-Gurgel, Sang Won Kwak, Hyeon-Cheol Kim, Franck Diemer

Objectives: The objective of this study was to evaluate the effects of transformational temperatures on the cyclic fatigue resistance at body temperature of reciprocating file systems: R motion (RM), Procodile Q (PQ), and Reciproc Blue.

Methods: Resistance test was done in a custom-made device at room (20°C ± 1°C) and body (37°C ± 1°C) temperatures within a 60° angle of curvature and 5 mm radius of the artificial canal. The time to fracture (TTF) was recorded. The scanning electron microscope observation and differential scanning calorimetry analyses were performed. Two-way analysis of variance and Tukey post-hoc comparison were applied at a significance level of 0.05.

Results: The results showed a significant influence of temperature on instrumental breakage, regardless of the file systems (p < 0.05). The TTF is significantly decreased at body temperature (p < 0.05). PQ showed the longest TTF in both temperature conditions (p < 0.05). RM demonstrated a significantly higher TTF reduction ratio compared to the other files (p < 0.05).

Conclusions: Within the limitations of this study, the heat-treated files with reciprocating kinetics may have different reduction ratios of the fatigue resistance of the file systems under different temperature conditions. This characteristic is an important point of consideration when clinicians select the file system to reduce potential file fracture.

目的:本研究的目的是评估转化温度对往复式文件系统:R运动(RM), procodiile Q (PQ)和Reciproc Blue在体温下的循环疲劳抗力的影响。方法:在定制的装置中,在室内(20°C±1°C)和体体(37°C±1°C)温度下,在人工根管60°曲率角和5 mm半径范围内进行电阻测试。记录骨折时间(TTF)。进行了扫描电镜观察和差示扫描量热分析。采用双向方差分析和Tukey事后比较,显著性水平为0.05。结果:无论采用何种文件系统,温度对器械破损均有显著影响(p < 0.05)。TTF在体温下显著降低(p < 0.05)。两种温度下,PQ均表现出最长的TTF (p < 0.05)。RM组TTF降低率显著高于其他组(p < 0.05)。结论:在本研究范围内,具有往复动力学的热处理锉在不同温度条件下,其疲劳抗力的降低率可能不同。当临床医生选择文件系统以减少潜在的文件骨折时,这一特征是一个重要的考虑点。
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Restorative Dentistry & Endodontics
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