Intussusception is a clinical disorder characterized by the telescoping of a proximal part of the bowel into its distal part. The point that invaginates into its adjacent part is known as the "Intussusceptum" (also referred to as the lead point), while the distal segment that receives the folding is known as the ''Intussuscipien''. This is one of the most important causes of acute abdomen in children, particularly infants and toddlers (3 months 3 years), however it is a rare condition in adults and brings about a variety of symptoms and patterns; be it acute, intermittent, or chronic. This disorder particularly triggers worrisome matters that are deemed target worthy in the clinical setting. One of these matters is managing the possible shock that comes about with the excessive compromise of the mesenteric blood supply, which ends up thickening the intestinal wall leading to fatal complications of ischemia and perforation. Intussusception's diagnostic approach also happens to be its therapeutic approach, which is non-operative reduction (be it air or barium enema). The recurrence risk of Intussusception is one that demands a cautious observation in an in-patient setting, as the reduction management helps in limiting said risk allowing the recurrence to alter between 24 and 48 hours onwards. In recent years, there has been a presentation of this disorder in children who were provided with the Rotavirus vaccine bringing about different post-marketing surveillances to understand the possible risks of developing Intussusception. Along with the general overview on the topic of Intussusception the following highlights will be included: an emphasis on the potential complications of Intussusception, its distinguishing presentation between children and adults, favoring air over liquid enema in reduction management, and Intussusception's increasing risk if/when the Rotavirus vaccine is given.
{"title":"Intussusception: Highlighted Aspects","authors":"A. Almaiman","doi":"10.33425/2639-9334.1020","DOIUrl":"https://doi.org/10.33425/2639-9334.1020","url":null,"abstract":"Intussusception is a clinical disorder characterized by the telescoping of a proximal part of the bowel into its distal part. The point that invaginates into its adjacent part is known as the \"Intussusceptum\" (also referred to as the lead point), while the distal segment that receives the folding is known as the ''Intussuscipien''. This is one of the most important causes of acute abdomen in children, particularly infants and toddlers (3 months 3 years), however it is a rare condition in adults and brings about a variety of symptoms and patterns; be it acute, intermittent, or chronic. This disorder particularly triggers worrisome matters that are deemed target worthy in the clinical setting. One of these matters is managing the possible shock that comes about with the excessive compromise of the mesenteric blood supply, which ends up thickening the intestinal wall leading to fatal complications of ischemia and perforation. Intussusception's diagnostic approach also happens to be its therapeutic approach, which is non-operative reduction (be it air or barium enema). The recurrence risk of Intussusception is one that demands a cautious observation in an in-patient setting, as the reduction management helps in limiting said risk allowing the recurrence to alter between 24 and 48 hours onwards. In recent years, there has been a presentation of this disorder in children who were provided with the Rotavirus vaccine bringing about different post-marketing surveillances to understand the possible risks of developing Intussusception. Along with the general overview on the topic of Intussusception the following highlights will be included: an emphasis on the potential complications of Intussusception, its distinguishing presentation between children and adults, favoring air over liquid enema in reduction management, and Intussusception's increasing risk if/when the Rotavirus vaccine is given.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-10-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123111852","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2018-07-26DOI: 10.32474/ddipij.2018.02.000129
R. Skopec
State Department evacuates a number of Americans from the U.S. consulate in Guangzhou, China after they experienced unexplained health issues. A group of U.S. diplomats stationed in China have been brought back to the states after being inflicted by a mystery illness that reportedly resembles the brain injuries previously suffered by staff in Cuba. Heather Nauert, a State Department spokeswoman, said in a statement that the individuals from the U.S. office in Guangzhou were returned home for further evaluation. It was unclear if there was any connection to last year’s situation in Cuba where 24 U.S. government employees experienced a range of ailments after hearing an unusual sound.
{"title":"Secret Sonic Weapons’ War Lead To Carcinogenesis","authors":"R. Skopec","doi":"10.32474/ddipij.2018.02.000129","DOIUrl":"https://doi.org/10.32474/ddipij.2018.02.000129","url":null,"abstract":"State Department evacuates a number of Americans from the U.S. consulate in Guangzhou, China after they experienced unexplained health issues. A group of U.S. diplomats stationed in China have been brought back to the states after being inflicted by a mystery illness that reportedly resembles the brain injuries previously suffered by staff in Cuba. Heather Nauert, a State Department spokeswoman, said in a statement that the individuals from the U.S. office in Guangzhou were returned home for further evaluation. It was unclear if there was any connection to last year’s situation in Cuba where 24 U.S. government employees experienced a range of ailments after hearing an unusual sound.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-07-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133337823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
M StepanovYu, Zavhorodnia N Yu, Lukianenko O Yu, G HravirovskaN, Yahmur V.B, Konenko I.S
{"title":"Influence of Pancreatic Steatosis on the Structural Changes of the Liver and Pancreas in Children with Overweight and Obesity","authors":"M StepanovYu, Zavhorodnia N Yu, Lukianenko O Yu, G HravirovskaN, Yahmur V.B, Konenko I.S","doi":"10.33425/2639-9334.1013","DOIUrl":"https://doi.org/10.33425/2639-9334.1013","url":null,"abstract":"","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124437241","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A 41-year-old man presented with persistent fevers and elevated liver enzymes. Percutaneous liver biopsy revealed fibrin ring granulomas and serologic testing confirmed acute Q fever. Interestingly, his fevers did not resolve with doxycycline alone, and he only clinically improved after hydroxychloroquine was initiated. We discuss the differential diagnosis of fibrinring granulomas on liver biopsy as well as the clinical features and treatment of Q fever. Case Report Citation: Melissa Magrath, Michelle Pearlman, Lan Peng, et al. Granulomatous Hepatitis and Persistent Fever of Unknown Origin: A Case Report. Gastroint Hepatol Dig Dis. 2018; 1(2): 1-2.
一名41岁男性表现为持续发热和肝酶升高。经皮肝活检显示纤维蛋白环肉芽肿，血清学检查证实急性Q热。有趣的是，他的发烧并没有单独使用强力霉素解决，他只是在羟氯喹开始后才有临床好转。我们讨论肝活检纤维化肉芽肿的鉴别诊断以及Q热的临床特点和治疗。病例报告引用:Melissa Magrath, Michelle Pearlman, Lan Peng等。肉芽肿性肝炎并不明原因持续发热1例报告。国际肝病杂志2018;1(2): 1 - 2。
{"title":"Granulomatous Hepatitis and Persistent Fever of Unknown Origin: A Case Report","authors":"M. Magrath, M. Pearlman, Lan Peng, William Lee","doi":"10.33425/2639-9334.1009","DOIUrl":"https://doi.org/10.33425/2639-9334.1009","url":null,"abstract":"A 41-year-old man presented with persistent fevers and elevated liver enzymes. Percutaneous liver biopsy revealed fibrin ring granulomas and serologic testing confirmed acute Q fever. Interestingly, his fevers did not resolve with doxycycline alone, and he only clinically improved after hydroxychloroquine was initiated. We discuss the differential diagnosis of fibrinring granulomas on liver biopsy as well as the clinical features and treatment of Q fever. Case Report Citation: Melissa Magrath, Michelle Pearlman, Lan Peng, et al. Granulomatous Hepatitis and Persistent Fever of Unknown Origin: A Case Report. Gastroint Hepatol Dig Dis. 2018; 1(2): 1-2.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125441146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Falih M. Algazgooz, Ali Dawood Al-Hilf, W. H. Al-Sewadi
Objective: Obesity among the most common nutritional disorders is rising worldwide. It lead to many health problems like metabolic disorders, strock and even cancer. We share our experience by using air-filled gastric balloon (heliosphere type). Its safety, tolerability and its efficacy in weight reduction. Methods: This study was conducted on 106 patients at one center (Al-Sadr Teaching Hospital) for the period from June 2014 to June 2015, using air-filled gastric balloon with air inflation of 600-720 ml. The BMI of the patients was (36-58) with the prevalence of 44% male and 56% females. After consent, preballoon investigation tests, balloon was inserted with the aid of conscious sedation at the endoscopy unit. The balloon was filled with 600-720 ml of air. All patients following the procedure were given analgesia and antiemetic for five days and PPIs for six months. Diet and the importance of the exercise were part of the preballoon insertion phase and protocol. The balloon was removed after 6 months. Results: In this study, the 106 patients with BMI (36-58) were subjected for introduction of air-filled gastric balloons over a period of six months and a follow up for them continued for up to two years. Our patients were classified into three categories: Acceptable or good weight reduction with a mean weight reduction of 13.5 kgs, failure of weight reduction and early removal of the balloon due to unacceptable periodic pain and gastric ulcer on follow up endoscopy. Conclusion: Despite the effective weight reduction in selected group of patients, the air filled gastric balloon is a temporary solution for obesity or as a bridge for surgery in sever morbidly obese patients. It has an unacceptable incidence of gastric ulcer.
{"title":"Yes or No for Heliosphere Airfilled Gastric Balloon","authors":"Falih M. Algazgooz, Ali Dawood Al-Hilf, W. H. Al-Sewadi","doi":"10.33425/2639-9334.1011","DOIUrl":"https://doi.org/10.33425/2639-9334.1011","url":null,"abstract":"Objective: Obesity among the most common nutritional disorders is rising worldwide. It lead to many health problems like metabolic disorders, strock and even cancer. We share our experience by using air-filled gastric balloon (heliosphere type). Its safety, tolerability and its efficacy in weight reduction. Methods: This study was conducted on 106 patients at one center (Al-Sadr Teaching Hospital) for the period from June 2014 to June 2015, using air-filled gastric balloon with air inflation of 600-720 ml. The BMI of the patients was (36-58) with the prevalence of 44% male and 56% females. After consent, preballoon investigation tests, balloon was inserted with the aid of conscious sedation at the endoscopy unit. The balloon was filled with 600-720 ml of air. All patients following the procedure were given analgesia and antiemetic for five days and PPIs for six months. Diet and the importance of the exercise were part of the preballoon insertion phase and protocol. The balloon was removed after 6 months. Results: In this study, the 106 patients with BMI (36-58) were subjected for introduction of air-filled gastric balloons over a period of six months and a follow up for them continued for up to two years. Our patients were classified into three categories: Acceptable or good weight reduction with a mean weight reduction of 13.5 kgs, failure of weight reduction and early removal of the balloon due to unacceptable periodic pain and gastric ulcer on follow up endoscopy. Conclusion: Despite the effective weight reduction in selected group of patients, the air filled gastric balloon is a temporary solution for obesity or as a bridge for surgery in sever morbidly obese patients. It has an unacceptable incidence of gastric ulcer.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115780244","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Luke B. Hartford, Alexsi Sherazadishvili, K. Leslie, J. Parfitt
{"title":"A Systematic Review of the Histopathology and Immunochemistry in Duodenal Gangliocytic Paragangliomas with Lymph Node Metastases to Identify Predictors of Malignancy","authors":"Luke B. Hartford, Alexsi Sherazadishvili, K. Leslie, J. Parfitt","doi":"10.33425/2639-9334.1010","DOIUrl":"https://doi.org/10.33425/2639-9334.1010","url":null,"abstract":"","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128975843","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Introduction: Surgery is a more effective option for pain relief in chronic pancreatitis. It relates to those patients, who don't have an increase in the head of the pancreas, and there is only dilatation of the main pancreatic duct, a good result can give the performance of laparoscopic longitudinal pancreatojejunostomy. Materials and Methods: Four attempts of laparoscopic lateral pancreatojejunostomy were made in patients with early chronic pancreatitis without an increase in the head of the pancreas. There were two females and two men and average age was 42,6. The indications for surgery in all patients was abdominal pain and dilatation main pancreatic duct (the average diameter was 12,8 mm). We used five-port technique. After opening omental bursa, we found, punctured and opened the main pancreatic duct. Then, using two linear staplers Endo-Gia 60 to handle the jejunum loops by Roux-en-Y. We we performed single-row longitudinal pancreatojejunostomy with barbed-suture V-Loc. Results: We had two conversions to open surgery, because of theinability to find the main pancreatic duct and bleeding. The average operation time was 207 minutes. Post-operative stay was average 9 days and on median follow-up of 12 month. Post-operatively, there were no major morbidity and nil mortality. All patients had complete pain relief and significant weight gain. Conclusion: Laparoscopic longitudinal pancreaticojejunostomy is safe, effective and feasible, especially with "early chronic pancreatitis" without an increase in the head of the pancreas. Research Article Citation: Volodymyr Yareshko, Iurii Mikheiev. Laparoscopic Longitudinal Pancreatojejunostomy for Chronic Pancreatitis: Report of First Ukraine Experience. Gastroint Hepatol Dig Dis. 2018; 1(2): 1-4.
{"title":"Laparoscopic Longitudinal Pancreatojejunostomy for Chronic Pancreatitis: Report of First Ukraine Experience","authors":"V. Yareshko, I. Mikheiev","doi":"10.33425/2639-9334.1008","DOIUrl":"https://doi.org/10.33425/2639-9334.1008","url":null,"abstract":"Introduction: Surgery is a more effective option for pain relief in chronic pancreatitis. It relates to those patients, who don't have an increase in the head of the pancreas, and there is only dilatation of the main pancreatic duct, a good result can give the performance of laparoscopic longitudinal pancreatojejunostomy. Materials and Methods: Four attempts of laparoscopic lateral pancreatojejunostomy were made in patients with early chronic pancreatitis without an increase in the head of the pancreas. There were two females and two men and average age was 42,6. The indications for surgery in all patients was abdominal pain and dilatation main pancreatic duct (the average diameter was 12,8 mm). We used five-port technique. After opening omental bursa, we found, punctured and opened the main pancreatic duct. Then, using two linear staplers Endo-Gia 60 to handle the jejunum loops by Roux-en-Y. We we performed single-row longitudinal pancreatojejunostomy with barbed-suture V-Loc. Results: We had two conversions to open surgery, because of theinability to find the main pancreatic duct and bleeding. The average operation time was 207 minutes. Post-operative stay was average 9 days and on median follow-up of 12 month. Post-operatively, there were no major morbidity and nil mortality. All patients had complete pain relief and significant weight gain. Conclusion: Laparoscopic longitudinal pancreaticojejunostomy is safe, effective and feasible, especially with \"early chronic pancreatitis\" without an increase in the head of the pancreas. Research Article Citation: Volodymyr Yareshko, Iurii Mikheiev. Laparoscopic Longitudinal Pancreatojejunostomy for Chronic Pancreatitis: Report of First Ukraine Experience. Gastroint Hepatol Dig Dis. 2018; 1(2): 1-4.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117034578","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mimiesse-Monamou Jile Florient, A. Clausina, A. Mboumba, N. George, M. Arnaud, A. Brunel, N. Marlyse, Itoua-Ngaporo Ngala Akoa, Atipo Ibara Blaise Irénée, Rutaganda Eric, D. Gassaye, Moukassa Donatien, Ibara Jean-Rosaire
Introduction: HBV-HIV co-infection is a major public health problem. The objective of this study was to contribute to the improvement of management of HBV-HIV co-infected patients in Congo. Methods: This was a cross-sectional descriptive study conducted from January 1st to September 30th, 2016. We studied outpatients seen in hospitals and Integrated Health Center of Department of Lékoumou. Screening for HBsAg was done by rapid test (Heath Mate HBsAg plus test) and that of HIV 1 and 2 was done by immunoassay (ImmunocoCOMB II HIV). The detection of HBV DNA was made by the QIAGEN QIA Kit and the identification of genotypes by PCR product sequencing at the National Public Health Laboratory of Brazzaville. Results: During nine months of study period, 204 patients were enrolled to participate in this study. Male patients were 37.3% and female were 62.7%, with a sex ratio of 0.5. The mean age was 40.9 ± 13.4. The frequency of HBV-HIV co-infection was 2.4% (n = 5). Single infections accounted for 6.3% (n = 13) for HBV and 12.3% (n = 23) for HIV. Carriers of HBV DNA accounted for 7.8% (n = 16/204). Condom non-use was significantly associated with co-infection and mono-infection (P <0.05). HBV genotype E was more common in the study participants than genotype A. Conclusion: HIV-HBV co-infection exists. Despite the small sample size, the prevalence of infection with hepatitis B virus remains high. Two HBV genotypes, A and E, have been identified in co-infected and monoinfected patients.
{"title":"HBV Seroprevalence and Genetic Diversity among HIV Patients in the Department of Lekoumou in Congo Brazzaville","authors":"Mimiesse-Monamou Jile Florient, A. Clausina, A. Mboumba, N. George, M. Arnaud, A. Brunel, N. Marlyse, Itoua-Ngaporo Ngala Akoa, Atipo Ibara Blaise Irénée, Rutaganda Eric, D. Gassaye, Moukassa Donatien, Ibara Jean-Rosaire","doi":"10.33425/2639-9334.1014","DOIUrl":"https://doi.org/10.33425/2639-9334.1014","url":null,"abstract":"Introduction: HBV-HIV co-infection is a major public health problem. The objective of this study was to contribute to the improvement of management of HBV-HIV co-infected patients in Congo. Methods: This was a cross-sectional descriptive study conducted from January 1st to September 30th, 2016. We studied outpatients seen in hospitals and Integrated Health Center of Department of Lékoumou. Screening for HBsAg was done by rapid test (Heath Mate HBsAg plus test) and that of HIV 1 and 2 was done by immunoassay (ImmunocoCOMB II HIV). The detection of HBV DNA was made by the QIAGEN QIA Kit and the identification of genotypes by PCR product sequencing at the National Public Health Laboratory of Brazzaville. Results: During nine months of study period, 204 patients were enrolled to participate in this study. Male patients were 37.3% and female were 62.7%, with a sex ratio of 0.5. The mean age was 40.9 ± 13.4. The frequency of HBV-HIV co-infection was 2.4% (n = 5). Single infections accounted for 6.3% (n = 13) for HBV and 12.3% (n = 23) for HIV. Carriers of HBV DNA accounted for 7.8% (n = 16/204). Condom non-use was significantly associated with co-infection and mono-infection (P <0.05). HBV genotype E was more common in the study participants than genotype A. Conclusion: HIV-HBV co-infection exists. Despite the small sample size, the prevalence of infection with hepatitis B virus remains high. Two HBV genotypes, A and E, have been identified in co-infected and monoinfected patients.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116774203","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Narayanan, Brijesh B. Patel, David J. Bromberg, Meghana Vellanki, P. Foulis, P. Kulkarni
{"title":"Investigating the Prevalence and Progression of Serrated Polyps – Tampa VA Experience","authors":"S. Narayanan, Brijesh B. Patel, David J. Bromberg, Meghana Vellanki, P. Foulis, P. Kulkarni","doi":"10.33425/2639-9334.1012","DOIUrl":"https://doi.org/10.33425/2639-9334.1012","url":null,"abstract":"","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2018-06-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114893146","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Mohamed El. alawy, M. A. Elmagd, Wafaa Hassan, W. Maher, Mohamed Hassan
Background and Aim of Study: Eosinophilic Esophagitis (EoE) is a chronic immune/antigen-mediated esophageal disease characterized clinically by symptoms related to easophageal dysfunction and histologically by eosinophilpredominant inflammation. This study was performed to determine the prevelance of eosinophilic Esophagitis in Adult patients with Upper Gastrointestinal symptoms in Ismailia Governate, Egypt. Patients and Methods: This cross-sectional descriptive study recruited all patients with Upper Gastrointestinal Symptoms omitted for endoscopic evaluation at Suez Canal University Hospital, Endoscopic Unit, after giving written consent. Esophageal biopsy samples were obtained and histological evaluation for the presence of eosinophils was performed for every patient. EoE was defined with at least 15 eosinophils were present in a single high-power field. Results: Out of 354 adult patients with Upper Gastrointestinal symptoms underwent upper endoscopy, only 35 cases (10.2%) diagnosed as EoE based on presence of 15 eosinophils/HPF in esophageal biopsies. Conclusion: Patients with persistent symptoms of severe GERD, who do or do not respond to PPI should undergo UGI endoscopy with multiple biopsies to exclude EoE.
{"title":"Eosinophilic Esophagitis in Adult Patients with Upper Gastrointestinal Symptoms: a Cross-Sectional Study in Northeastern Egypt","authors":"Mohamed El. alawy, M. A. Elmagd, Wafaa Hassan, W. Maher, Mohamed Hassan","doi":"10.33425/2639-9334.1029","DOIUrl":"https://doi.org/10.33425/2639-9334.1029","url":null,"abstract":"Background and Aim of Study: Eosinophilic Esophagitis (EoE) is a chronic immune/antigen-mediated esophageal disease characterized clinically by symptoms related to easophageal dysfunction and histologically by eosinophilpredominant inflammation. This study was performed to determine the prevelance of eosinophilic Esophagitis in Adult patients with Upper Gastrointestinal symptoms in Ismailia Governate, Egypt. Patients and Methods: This cross-sectional descriptive study recruited all patients with Upper Gastrointestinal Symptoms omitted for endoscopic evaluation at Suez Canal University Hospital, Endoscopic Unit, after giving written consent. Esophageal biopsy samples were obtained and histological evaluation for the presence of eosinophils was performed for every patient. EoE was defined with at least 15 eosinophils were present in a single high-power field. Results: Out of 354 adult patients with Upper Gastrointestinal symptoms underwent upper endoscopy, only 35 cases (10.2%) diagnosed as EoE based on presence of 15 eosinophils/HPF in esophageal biopsies. Conclusion: Patients with persistent symptoms of severe GERD, who do or do not respond to PPI should undergo UGI endoscopy with multiple biopsies to exclude EoE.","PeriodicalId":211573,"journal":{"name":"Gastroenterology, Hepatology & Digestive Disorders","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128928357","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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