Pub Date : 2024-12-01Epub Date: 2024-11-22DOI: 10.30773/pi.2024.0162
Xiaoyu Zhuang, Qin Li, Susu Liu, Jieming Mo
Objective: This study is the first to adopt a cultural and contextual coping model to examine the impact of forbearance coping on compliance and psychological health and unravel the psychosocial mediator and moderator among community-dwelling residents in the post-pandemic era in China.
Methods: A multistage cluster convenience sampling strategy was conducted to recruit 402 community-dwelling residents of ten cities in Guangdong province who completed an online survey measuring forbearance coping, anti-pandemic compliance behaviours, family resilience, community resilience and psychological distress.
Results: The study results showed an unexpected negative influence of forbearance coping on psychological distress. Nevertheless, forbearance coping facilitated personal compliance with coronavirus disease-2019 mitigation measures and improved psychological health. More importantly, meaning-making of adversity within families partially mediated the negative effect of forbearance on mental health only when respondents perceived higher levels of community resilience.
Conclusion: This study is the first to apply the cultural and contextual model of coping to Chinese individuals during a significant public health crisis. It expands the model by uncovering mechanisms like behavioural compliance and family meaning-making, and highlights the moderating role of community resilience. The findings emphasize the importance of building resilient communities and supporting mental health, providing evidence for future policy interventions and pandemic/disaster prevention measures in China.
{"title":"Forbearance Coping, Community Resilience, Family Resilience and Mental Health During the Post-Pandemic in China: A Moderated Mediation Model.","authors":"Xiaoyu Zhuang, Qin Li, Susu Liu, Jieming Mo","doi":"10.30773/pi.2024.0162","DOIUrl":"10.30773/pi.2024.0162","url":null,"abstract":"<p><strong>Objective: </strong>This study is the first to adopt a cultural and contextual coping model to examine the impact of forbearance coping on compliance and psychological health and unravel the psychosocial mediator and moderator among community-dwelling residents in the post-pandemic era in China.</p><p><strong>Methods: </strong>A multistage cluster convenience sampling strategy was conducted to recruit 402 community-dwelling residents of ten cities in Guangdong province who completed an online survey measuring forbearance coping, anti-pandemic compliance behaviours, family resilience, community resilience and psychological distress.</p><p><strong>Results: </strong>The study results showed an unexpected negative influence of forbearance coping on psychological distress. Nevertheless, forbearance coping facilitated personal compliance with coronavirus disease-2019 mitigation measures and improved psychological health. More importantly, meaning-making of adversity within families partially mediated the negative effect of forbearance on mental health only when respondents perceived higher levels of community resilience.</p><p><strong>Conclusion: </strong>This study is the first to apply the cultural and contextual model of coping to Chinese individuals during a significant public health crisis. It expands the model by uncovering mechanisms like behavioural compliance and family meaning-making, and highlights the moderating role of community resilience. The findings emphasize the importance of building resilient communities and supporting mental health, providing evidence for future policy interventions and pandemic/disaster prevention measures in China.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":" ","pages":"1349-1359"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704809/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142688703","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: This study examined the mediating effect of negative changes in daily life due to the coronavirus disease-2019 (COVID-19) pandemic on depressive symptoms, considering COVID-19 infection and related social concerns. Additionally, comparisons of path coefficients between the groups were conducted based on age and gender.
Methods: A cross-sectional study design used data from the 2020 Korean Community Health Survey consisting of 229,269 individuals. This study used a self-reported questionnaire, including the Patient Health Questionnaire-9 and three items addressing social concerns related to COVID-19 infection. A single question assessed whether individuals had experienced COVID-19 infection within the last 3 months, and scores of negative changes in daily life due to the COVID-19 pandemic. Correlation analysis was performed on the variables. Structural equation model analysis was conducted to identify the mediating role of negative changes in daily life. Chi-square tests were also performed to compare the path coefficients based on age and gender.
Results: The structural equation models revealed that COVID-19 infection and related social concerns had both significant direct effects on depressive symptoms and indirect effects through negative changes in daily life. When comparing the path coefficients by age and gender, the coefficients related to depressive symptoms were highest in those under 65 years and in females.
Conclusion: Negative changes in daily life due to the COVID-19 pandemic serve as a partial mediator of the impact of COVID-19 infection and related social concerns on depressive symptoms. Special attention should be paid to depressive symptoms in those under 65 years of age and in females.
{"title":"Impact of COVID-19 Infection and Related Social Concerns on Depressive Symptoms: Mediating Effects of Negative Changes in Daily Life and Moderating Effects of Age and Gender.","authors":"Dham Ho, Sun-Young Kim, Hye Ah Lee, Hyunsun Cho, Weon-Jeong Lim","doi":"10.30773/pi.2024.0159","DOIUrl":"10.30773/pi.2024.0159","url":null,"abstract":"<p><strong>Objective: </strong>This study examined the mediating effect of negative changes in daily life due to the coronavirus disease-2019 (COVID-19) pandemic on depressive symptoms, considering COVID-19 infection and related social concerns. Additionally, comparisons of path coefficients between the groups were conducted based on age and gender.</p><p><strong>Methods: </strong>A cross-sectional study design used data from the 2020 Korean Community Health Survey consisting of 229,269 individuals. This study used a self-reported questionnaire, including the Patient Health Questionnaire-9 and three items addressing social concerns related to COVID-19 infection. A single question assessed whether individuals had experienced COVID-19 infection within the last 3 months, and scores of negative changes in daily life due to the COVID-19 pandemic. Correlation analysis was performed on the variables. Structural equation model analysis was conducted to identify the mediating role of negative changes in daily life. Chi-square tests were also performed to compare the path coefficients based on age and gender.</p><p><strong>Results: </strong>The structural equation models revealed that COVID-19 infection and related social concerns had both significant direct effects on depressive symptoms and indirect effects through negative changes in daily life. When comparing the path coefficients by age and gender, the coefficients related to depressive symptoms were highest in those under 65 years and in females.</p><p><strong>Conclusion: </strong>Negative changes in daily life due to the COVID-19 pandemic serve as a partial mediator of the impact of COVID-19 infection and related social concerns on depressive symptoms. Special attention should be paid to depressive symptoms in those under 65 years of age and in females.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 12","pages":"1318-1328"},"PeriodicalIF":1.8,"publicationDate":"2024-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11704799/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142932550","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2024.0201
So Hee Lee, Kyoung-Beom Kim, Jin-Won Noh, Myong-Wuk Chon, Eun Ji Kim, Jeong-Ho Chae
Objective: Disaster survivors often experience negative impacts on their mental health, but some may also exhibit posttraumatic growth, overcoming adversity, and finding positive outcomes. This study aimed to identify psychological factors influencing posttraumatic growth (PTG) among students who survived the Sewol ferry disaster.
Methods: The study used a longitudinal design. Data were collected at 6-month intervals between high school graduation and 6 years after the ferry disaster. Data were obtained from 48 adolescents who completed self-report measures of rumination, meaning in life, coping, PTG, family adaptability and cohesion. Generalized estimating equation models were fitted to 11 waves of follow-up data.
Results: Intrusive rumination (coefficient [coef]=0.165; p<0.001; 95% confidence interval [CI] 0.081-0.250) and deliberate rumination (coef=0.554; p<0.001; 95% CI 0.376-0.732) were significantly associated with PTG. Concerning meaning in life, the presence of meaning (coef=0.312; p<0.001; 95% CI 0.189-0.435) and the search for meaning (coef=0.216; p=0.001; 95% CI 0.093-0.340) were also significantly associated with PTG. Finally, the problem-focused (coef=0.682; p=0.011; 95% CI 0.153-1.210) and emotion-focused (coef=0.736; p=0.009; 95% CI 0.186-1.285) coping strategies both showed significant associations with PTG.
Conclusion: The results of this study indicate that rumination, meaning in life, and adaptive coping (including cognitive and emotional coping) were protective factors for mental health problems among adolescents who survived the Sewol ferry disaster. These psychological factors may promote PTG over time.
{"title":"Factors Influencing Post-Traumatic Growth in Surviving Students of the Sewol Ferry Disaster: A Long-Term Follow-Up Study.","authors":"So Hee Lee, Kyoung-Beom Kim, Jin-Won Noh, Myong-Wuk Chon, Eun Ji Kim, Jeong-Ho Chae","doi":"10.30773/pi.2024.0201","DOIUrl":"10.30773/pi.2024.0201","url":null,"abstract":"<p><strong>Objective: </strong>Disaster survivors often experience negative impacts on their mental health, but some may also exhibit posttraumatic growth, overcoming adversity, and finding positive outcomes. This study aimed to identify psychological factors influencing posttraumatic growth (PTG) among students who survived the Sewol ferry disaster.</p><p><strong>Methods: </strong>The study used a longitudinal design. Data were collected at 6-month intervals between high school graduation and 6 years after the ferry disaster. Data were obtained from 48 adolescents who completed self-report measures of rumination, meaning in life, coping, PTG, family adaptability and cohesion. Generalized estimating equation models were fitted to 11 waves of follow-up data.</p><p><strong>Results: </strong>Intrusive rumination (coefficient [coef]=0.165; p<0.001; 95% confidence interval [CI] 0.081-0.250) and deliberate rumination (coef=0.554; p<0.001; 95% CI 0.376-0.732) were significantly associated with PTG. Concerning meaning in life, the presence of meaning (coef=0.312; p<0.001; 95% CI 0.189-0.435) and the search for meaning (coef=0.216; p=0.001; 95% CI 0.093-0.340) were also significantly associated with PTG. Finally, the problem-focused (coef=0.682; p=0.011; 95% CI 0.153-1.210) and emotion-focused (coef=0.736; p=0.009; 95% CI 0.186-1.285) coping strategies both showed significant associations with PTG.</p><p><strong>Conclusion: </strong>The results of this study indicate that rumination, meaning in life, and adaptive coping (including cognitive and emotional coping) were protective factors for mental health problems among adolescents who survived the Sewol ferry disaster. These psychological factors may promote PTG over time.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1279-1285"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611457/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751406","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2024.0265
Turgut Dolanbay, Abdussamed Vural, Mustafa Cihan Altay, Nesibe Sultan Çınaroglu
Objective: The present study evaluated the work-related anxiety scores of healthcare workers in emergency departments (ED) and aimed to determine the factors affecting these scores.
Methods: The data was obtained through a survey administered to the emergency staff. Beck's Anxiety Inventory (BAI) and the Mini-International Neuropsychiatric Interview (MINI) work anxiety interview were used to predict and determine the type of anxiety experienced by the participants. The survey was administered to 147 volunteers, and questionnaires from 130 participants were included in the study.
Results: It was found that 43.8% of the participants had a BAI score greater than 7. The study results showed a negative correlation and a linear regression model between age and the BAI score. Additionally, the BAI score was significantly higher in female, singles, physicians, those who were dissatisfied with their jobs, and those who were dissatisfied with their salaries (p<0.05). The results also showed that having a history of anxiety disorder or depression, being a physician, and being dissatisfied with one's job were 6.277, 5.583, and 4.005 times higher, respectively, in terms of suspicion of anxiety (p<0.001). In the MINI job anxiety interview, work-related posttraumatic stress disorder (38.6%) was predicted most frequently, and indiscriminative work-related social phobia (5.3%) was predicted least frequently in participants at risk for anxiety according to the BAI score.
Conclusion: This study suggests that teaching healthcare workers how to cope with workplace trauma and workplace-related situational phobias can be an effective solution to prevent anxiety disorders in healthcare workers working in ED.
{"title":"Level of Work-Related Anxiety and Potential Causes of Anxiety in Healthcare Workers in the Emergency Department.","authors":"Turgut Dolanbay, Abdussamed Vural, Mustafa Cihan Altay, Nesibe Sultan Çınaroglu","doi":"10.30773/pi.2024.0265","DOIUrl":"10.30773/pi.2024.0265","url":null,"abstract":"<p><strong>Objective: </strong>The present study evaluated the work-related anxiety scores of healthcare workers in emergency departments (ED) and aimed to determine the factors affecting these scores.</p><p><strong>Methods: </strong>The data was obtained through a survey administered to the emergency staff. Beck's Anxiety Inventory (BAI) and the Mini-International Neuropsychiatric Interview (MINI) work anxiety interview were used to predict and determine the type of anxiety experienced by the participants. The survey was administered to 147 volunteers, and questionnaires from 130 participants were included in the study.</p><p><strong>Results: </strong>It was found that 43.8% of the participants had a BAI score greater than 7. The study results showed a negative correlation and a linear regression model between age and the BAI score. Additionally, the BAI score was significantly higher in female, singles, physicians, those who were dissatisfied with their jobs, and those who were dissatisfied with their salaries (p<0.05). The results also showed that having a history of anxiety disorder or depression, being a physician, and being dissatisfied with one's job were 6.277, 5.583, and 4.005 times higher, respectively, in terms of suspicion of anxiety (p<0.001). In the MINI job anxiety interview, work-related posttraumatic stress disorder (38.6%) was predicted most frequently, and indiscriminative work-related social phobia (5.3%) was predicted least frequently in participants at risk for anxiety according to the BAI score.</p><p><strong>Conclusion: </strong>This study suggests that teaching healthcare workers how to cope with workplace trauma and workplace-related situational phobias can be an effective solution to prevent anxiety disorders in healthcare workers working in ED.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1299-1307"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611459/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Self-determination theory (SDT) deems that people have three causality orientations: autonomy orientation, control orientation, and impersonal orientation. Previous studies suggested that lower autonomy orientation or higher control and impersonal orientations may be associated with more addictive behaviors. Our study aimed to investigate if these associations exist in Internet gaming disorder (IGD), and if sensation seeking, anxiety, and depression could influence the associations between causality orientations and IGD symptoms.
Methods: A total of 1,400 college students completed the Internet Gaming Disorder Scale, General Causality Orientation Scale, Brief Sensation Seeking Scale, Generalized Anxiety Disorder Scale, and Patient Health Questionnaire. Correlation, multiple linear regressions, structural equation model (SEM) analyses, and moderation analyses were conducted to explore the associations.
Results: The control and impersonal orientations were positively associated with IGD symptoms, while the autonomy orientation was negatively associated with them. Moreover, SEM analyses showed that the autonomy-IGD relationship was totally mediated by anxiety and depression, the impersonal-IGD relationship was partially mediated by anxiety, and the control-IGD relationship was partially mediated by depression. Finally, the effects of causality orientations on IGD were moderated by sensation seeking.
Conclusion: Overall, autonomy orientation is linked to fewer gaming problems, whereas control and impersonal orientations are associated with more gaming problems. Moreover, the relationships between causality orientations and IGD symptoms are mediated by anxiety and depression and moderated by sensation seeking. Our findings inform theory on the motivations of gaming behaviors and may shed light on the prevention and intervention of IGD from the perspective of SDT.
{"title":"The Association Between Causality Orientation and Internet Gaming Disorder, and the Role of Sensation Seeking, Anxiety, and Depression.","authors":"Yanjie Peng, Yuxiang Wang, Zhenlei Peng, Xiaoyuan Liao, Ke Gong, Cheng Qin, Mingyuan Tian, Xiaotong Cheng, Xinyi Zhou, Juan Deng, Yuwen Chen, Shuang Feng, Maomao Zhang, Kezhi Liu, Bo Xiang, Wei Lei, Jing Chen","doi":"10.30773/pi.2024.0122","DOIUrl":"10.30773/pi.2024.0122","url":null,"abstract":"<p><strong>Objective: </strong>Self-determination theory (SDT) deems that people have three causality orientations: autonomy orientation, control orientation, and impersonal orientation. Previous studies suggested that lower autonomy orientation or higher control and impersonal orientations may be associated with more addictive behaviors. Our study aimed to investigate if these associations exist in Internet gaming disorder (IGD), and if sensation seeking, anxiety, and depression could influence the associations between causality orientations and IGD symptoms.</p><p><strong>Methods: </strong>A total of 1,400 college students completed the Internet Gaming Disorder Scale, General Causality Orientation Scale, Brief Sensation Seeking Scale, Generalized Anxiety Disorder Scale, and Patient Health Questionnaire. Correlation, multiple linear regressions, structural equation model (SEM) analyses, and moderation analyses were conducted to explore the associations.</p><p><strong>Results: </strong>The control and impersonal orientations were positively associated with IGD symptoms, while the autonomy orientation was negatively associated with them. Moreover, SEM analyses showed that the autonomy-IGD relationship was totally mediated by anxiety and depression, the impersonal-IGD relationship was partially mediated by anxiety, and the control-IGD relationship was partially mediated by depression. Finally, the effects of causality orientations on IGD were moderated by sensation seeking.</p><p><strong>Conclusion: </strong>Overall, autonomy orientation is linked to fewer gaming problems, whereas control and impersonal orientations are associated with more gaming problems. Moreover, the relationships between causality orientations and IGD symptoms are mediated by anxiety and depression and moderated by sensation seeking. Our findings inform theory on the motivations of gaming behaviors and may shed light on the prevention and intervention of IGD from the perspective of SDT.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1268-1278"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611462/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751464","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Objective: Dentists encounter unique occupational challenges, including stress, depression, and anxiety, that can impact their mental well-being. Therefore, it is essential to identify dentists' mental health statuses and the factors influencing them. Understanding the heterogeneity in dentists' mental health is crucial for tailored interventions. To investigate different mental health profiles within the dentist population and understand the characteristics of each type.
Methods: In this cross-sectional study, we surveyed 261 Korean dentists from a sample of 1,520. Using latent profile analysis, participants were classified into distinct mental health profiles based on self-reported stress, depressive symptoms, anxiety, and sleep quality. Demographic and occupational variables were analyzed to explore their association with mental health profiles.
Results: Three distinct mental health profiles were identified: high, moderate, and low. Factors such as drinking frequency, socioeconomic status, income, and work hours significantly influenced profile classification. Significant differences in job satisfaction were observed among the profiles.
Conclusion: This study underscores the importance of personalized interventions to address the specific needs of each mental health profile, aiming to improve job satisfaction and overall mental health in the dental profession.
{"title":"Mental Health Status Profiles of Dentists in South Korea: A Latent Profile Analysis Approach.","authors":"Chisung Yuh, Sojin Yoon, Kyungwon Song, Heon-Jeong Lee, Young-Mee Lee, Chul-Hyun Cho","doi":"10.30773/pi.2024.0115","DOIUrl":"10.30773/pi.2024.0115","url":null,"abstract":"<p><strong>Objective: </strong>Dentists encounter unique occupational challenges, including stress, depression, and anxiety, that can impact their mental well-being. Therefore, it is essential to identify dentists' mental health statuses and the factors influencing them. Understanding the heterogeneity in dentists' mental health is crucial for tailored interventions. To investigate different mental health profiles within the dentist population and understand the characteristics of each type.</p><p><strong>Methods: </strong>In this cross-sectional study, we surveyed 261 Korean dentists from a sample of 1,520. Using latent profile analysis, participants were classified into distinct mental health profiles based on self-reported stress, depressive symptoms, anxiety, and sleep quality. Demographic and occupational variables were analyzed to explore their association with mental health profiles.</p><p><strong>Results: </strong>Three distinct mental health profiles were identified: high, moderate, and low. Factors such as drinking frequency, socioeconomic status, income, and work hours significantly influenced profile classification. Significant differences in job satisfaction were observed among the profiles.</p><p><strong>Conclusion: </strong>This study underscores the importance of personalized interventions to address the specific needs of each mental health profile, aiming to improve job satisfaction and overall mental health in the dental profession.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1193-1202"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611469/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2024.0164
Yanzhe Li, Xue Yu, Zhonghui Ma, Qinghe Liu, Min Li, Xue Tian, Baozhu Li, Ran Zhang, Pei Gu, Fengfeng Bai, Guoshuai Luo, Meijuan Li, Daliang Sun
Objective: The aging demographic landscape worldwide portends a heightened prevalence of neurodegenerative disorders. Foremost among these is Alzheimer's disease (AD), the foremost cause of dementia in older adults. The shortage of efficacious therapies and early diagnostic indicators underscores the imperative to identify non-invasive biomarkers for early detection and disease monitoring. Recently, blood metabolites have emerged as promising candidates for AD biomarkers.
Methods: Leveraging nuclear magnetic resonance (NMR) spectroscopy on plasma specimens, we conducted a cross-sectional study encompassing 35 AD patients and 35 age-matched healthy controls. Cognitive function was evaluated using the mini-mental state examination in all participants, followed by peripheral blood sample collection. We utilized univariate and multivariate analyses to perform targeted lipidomic profiling via NMR spectroscopy.
Results: Our study revealed significant differences in the expression profiles of low-density lipoprotein-associated subfractions in females and high-density lipoprotein-associated subfractions in males between AD patients and healthy controls (all p<0.05). However, there was no significant metabolite overlap between males and females. Furthermore, receiver operating characteristic curve analysis demonstrated that the combination of lipid metabolites had good diagnostic values (all area under the curve>0.70; p<0.05).
Conclusion: Our findings suggest that the blood plasma samples using NMR hold promise in distinguishing between AD patients and healthy controls, with significant clinical implications for advancing AD diagnostic methodologies.
{"title":"Nuclear Magnetic Resonance Analysis Implicates Sex-Specific Dysregulation of the Blood Lipids in Alzheimer's Disease: A Retrospective Health-Controlled Study.","authors":"Yanzhe Li, Xue Yu, Zhonghui Ma, Qinghe Liu, Min Li, Xue Tian, Baozhu Li, Ran Zhang, Pei Gu, Fengfeng Bai, Guoshuai Luo, Meijuan Li, Daliang Sun","doi":"10.30773/pi.2024.0164","DOIUrl":"10.30773/pi.2024.0164","url":null,"abstract":"<p><strong>Objective: </strong>The aging demographic landscape worldwide portends a heightened prevalence of neurodegenerative disorders. Foremost among these is Alzheimer's disease (AD), the foremost cause of dementia in older adults. The shortage of efficacious therapies and early diagnostic indicators underscores the imperative to identify non-invasive biomarkers for early detection and disease monitoring. Recently, blood metabolites have emerged as promising candidates for AD biomarkers.</p><p><strong>Methods: </strong>Leveraging nuclear magnetic resonance (NMR) spectroscopy on plasma specimens, we conducted a cross-sectional study encompassing 35 AD patients and 35 age-matched healthy controls. Cognitive function was evaluated using the mini-mental state examination in all participants, followed by peripheral blood sample collection. We utilized univariate and multivariate analyses to perform targeted lipidomic profiling via NMR spectroscopy.</p><p><strong>Results: </strong>Our study revealed significant differences in the expression profiles of low-density lipoprotein-associated subfractions in females and high-density lipoprotein-associated subfractions in males between AD patients and healthy controls (all p<0.05). However, there was no significant metabolite overlap between males and females. Furthermore, receiver operating characteristic curve analysis demonstrated that the combination of lipid metabolites had good diagnostic values (all area under the curve>0.70; p<0.05).</p><p><strong>Conclusion: </strong>Our findings suggest that the blood plasma samples using NMR hold promise in distinguishing between AD patients and healthy controls, with significant clinical implications for advancing AD diagnostic methodologies.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1211-1220"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611466/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751457","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2023.0351
Kyungho Lim, Jiwon Baek, Hokon Kim, Ocksim Kim, Sang Hui Chu, Young-Chul Jung
Objective: This study aimed to explore the relationship between suicidal ideation and specific trauma and social discrimination among North Korean defectors.
Methods: A total of 448 North Korean defectors were recruited from online and offline communities and counseling centers. Participants provided sociodemographic and psychiatric history information via an online survey. Various assessment tools, including the Traumatic Event Checklist for North Korean Defectors, International Trauma Questionnaire, Experiences of Discrimination Scale, UCLA Loneliness Scale (short-form), and World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF), were employed. Multiple logistic regression analysis was used to examine the association between suicidal ideation and different types of trauma and discrimination.
Results: Among participants, 38.4% reported experiencing suicidal ideation. The most prevalent trauma was "unwanted separation from spouse, parent, or sibling" (69.4%), and the primary form of discrimination was "unfairness during employment" (35.7%). After adjusting for relevant variables, experiencing "extreme life-threatening hardship," "unwanted separation from a child," and "discrimination in income" significantly increased the likelihood of suicidal ideation. Importantly, unlike other refugee groups, interpersonal violence like torture or sexual abuse did not significantly contribute to suicidal ideation in this population. These findings highlight the unique vulnerabilities of North Korean defectors and suggest that income-related discrimination, unwanted separation from children, and life-threatening hardships are critical factors influencing suicidal ideation. Limitations such as recall biases and the cross-sectional nature of the data should be acknowledged.
Conclusion: This study underscores the need for tailored psychiatric support for North Korean defectors, recognizing their distinctive needs compared to other refugee populations.
{"title":"Relationship Between Trauma, Discrimination, and Suicidal Ideation Among North Korean Defectors.","authors":"Kyungho Lim, Jiwon Baek, Hokon Kim, Ocksim Kim, Sang Hui Chu, Young-Chul Jung","doi":"10.30773/pi.2023.0351","DOIUrl":"10.30773/pi.2023.0351","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to explore the relationship between suicidal ideation and specific trauma and social discrimination among North Korean defectors.</p><p><strong>Methods: </strong>A total of 448 North Korean defectors were recruited from online and offline communities and counseling centers. Participants provided sociodemographic and psychiatric history information via an online survey. Various assessment tools, including the Traumatic Event Checklist for North Korean Defectors, International Trauma Questionnaire, Experiences of Discrimination Scale, UCLA Loneliness Scale (short-form), and World Health Organization Quality of Life Instrument, Short Form (WHOQOL-BREF), were employed. Multiple logistic regression analysis was used to examine the association between suicidal ideation and different types of trauma and discrimination.</p><p><strong>Results: </strong>Among participants, 38.4% reported experiencing suicidal ideation. The most prevalent trauma was \"unwanted separation from spouse, parent, or sibling\" (69.4%), and the primary form of discrimination was \"unfairness during employment\" (35.7%). After adjusting for relevant variables, experiencing \"extreme life-threatening hardship,\" \"unwanted separation from a child,\" and \"discrimination in income\" significantly increased the likelihood of suicidal ideation. Importantly, unlike other refugee groups, interpersonal violence like torture or sexual abuse did not significantly contribute to suicidal ideation in this population. These findings highlight the unique vulnerabilities of North Korean defectors and suggest that income-related discrimination, unwanted separation from children, and life-threatening hardships are critical factors influencing suicidal ideation. Limitations such as recall biases and the cross-sectional nature of the data should be acknowledged.</p><p><strong>Conclusion: </strong>This study underscores the need for tailored psychiatric support for North Korean defectors, recognizing their distinctive needs compared to other refugee populations.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1203-1210"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611463/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751462","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2024.0154
Se Youl Kim, Sra Jung, Mi Yeon Lee, Kang-Seob Oh, Young-Chul Shin, Dong-Won Shin, Junhyung Kim, Eun Soo Kim, Sun Wook Jung, Kwang-Yeol Lee, Nahyun Oh, Sung Joon Cho, Sang-Won Jeon
Objective: This study aimed to examine the psychiatric impact of the Seoul Halloween crowd crush on individuals related to the victims compared to the general population. It also explores the moderating effect of resilience on the relationship between trauma exposure and psychiatric symptoms.
Methods: In total, 2,220 participants completed various post-incident questionnaires (Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hwa-byung symptom scale, post-traumatic stress disorder checklist for DSM-5, and Brief Resilience Scale) 30 days after the incident. Moderation analyses were conducted using the PROCESS macro in the statistical package for the social sciences.
Results: Individuals related to the victims exhibited higher symptom severity and a greater risk for clinically significant levels of depression, anxiety, anger, and post-traumatic stress disorder (PTSD) (odds ratio=3.28, 3.33, 1.51, and 4.39 respectively). The impact of relevance to victims on anxiety and PTSD symptoms was moderated by resilience, with a stronger effect observed for individuals with low resilience (β=3.51, 95% confidence interval [CI] 2.78-4.24 for anxiety and β=14.53, 95% CI 12.43-16.63 for PTSD) than for those with high resilience (β=1.69, 95% CI 0.72-2.65 for anxiety and β=8.33, 95% CI 5.56-11.09 for PTSD).
Conclusion: When related to the victims, it was found that not only PTSD, but also depression, anxiety, and anger could intensify. Resilience emerged as a potential buffer against these adverse effects, emphasizing its significance in mitigating the psychiatric impact of community trauma.
{"title":"The Moderating Effect of Resilience on the Relationship Between the Relevance to Victims With Post-Trauma Psychiatric Symptoms of Community Residents After Seoul Halloween Crowd Crush.","authors":"Se Youl Kim, Sra Jung, Mi Yeon Lee, Kang-Seob Oh, Young-Chul Shin, Dong-Won Shin, Junhyung Kim, Eun Soo Kim, Sun Wook Jung, Kwang-Yeol Lee, Nahyun Oh, Sung Joon Cho, Sang-Won Jeon","doi":"10.30773/pi.2024.0154","DOIUrl":"10.30773/pi.2024.0154","url":null,"abstract":"<p><strong>Objective: </strong>This study aimed to examine the psychiatric impact of the Seoul Halloween crowd crush on individuals related to the victims compared to the general population. It also explores the moderating effect of resilience on the relationship between trauma exposure and psychiatric symptoms.</p><p><strong>Methods: </strong>In total, 2,220 participants completed various post-incident questionnaires (Patient Health Questionnaire-9, Generalized Anxiety Disorder-7, Hwa-byung symptom scale, post-traumatic stress disorder checklist for DSM-5, and Brief Resilience Scale) 30 days after the incident. Moderation analyses were conducted using the PROCESS macro in the statistical package for the social sciences.</p><p><strong>Results: </strong>Individuals related to the victims exhibited higher symptom severity and a greater risk for clinically significant levels of depression, anxiety, anger, and post-traumatic stress disorder (PTSD) (odds ratio=3.28, 3.33, 1.51, and 4.39 respectively). The impact of relevance to victims on anxiety and PTSD symptoms was moderated by resilience, with a stronger effect observed for individuals with low resilience (β=3.51, 95% confidence interval [CI] 2.78-4.24 for anxiety and β=14.53, 95% CI 12.43-16.63 for PTSD) than for those with high resilience (β=1.69, 95% CI 0.72-2.65 for anxiety and β=8.33, 95% CI 5.56-11.09 for PTSD).</p><p><strong>Conclusion: </strong>When related to the victims, it was found that not only PTSD, but also depression, anxiety, and anger could intensify. Resilience emerged as a potential buffer against these adverse effects, emphasizing its significance in mitigating the psychiatric impact of community trauma.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1183-1192"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611461/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751379","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-11-01Epub Date: 2024-11-18DOI: 10.30773/pi.2023.0432
Jin Young Choi, Subin Park
Objective: We aimed to identify subgroups of suicide risk and their characteristics among Korean adults.
Methods: We used data from the National Mental Health Survey of Korea 2021. Participants were 5,511 adults aged 18-79 years. Latent class analysis was conducted to identify patterns of suicide risk using suicidal thoughts, plans, attempts, and self-harm. Sociodemographic and health-related characteristics according to the subtype of suicide risk were compared.
Results: Suicide risk was classified into three latent classes: low suicide risk (89.5%, Class 3 [C3]), high suicidal ideation and low suicidal behavior (8.7%, Class 2 [C2]), and high suicidal thoughts and behavior (1.8%, Class 1 [C1]). Risk factors associated with C1 and C2 were the absence of a spouse, low educational and economic status, and unstable occupational status. C1 and C2 had more physical and psychological problems than did C3. Prevalence of mental disorders and mental health service use were higher in C1 than in C2.
Conclusion: Suicide risk types have different demographic, physical health-related, and mental health-related characteristics. Therefore, a focused and individualized suicide preventive strategy should be implemented.
{"title":"Latent Subtypes and Characteristics of Suicide Risk Among Korean Adults.","authors":"Jin Young Choi, Subin Park","doi":"10.30773/pi.2023.0432","DOIUrl":"10.30773/pi.2023.0432","url":null,"abstract":"<p><strong>Objective: </strong>We aimed to identify subgroups of suicide risk and their characteristics among Korean adults.</p><p><strong>Methods: </strong>We used data from the National Mental Health Survey of Korea 2021. Participants were 5,511 adults aged 18-79 years. Latent class analysis was conducted to identify patterns of suicide risk using suicidal thoughts, plans, attempts, and self-harm. Sociodemographic and health-related characteristics according to the subtype of suicide risk were compared.</p><p><strong>Results: </strong>Suicide risk was classified into three latent classes: low suicide risk (89.5%, Class 3 [C3]), high suicidal ideation and low suicidal behavior (8.7%, Class 2 [C2]), and high suicidal thoughts and behavior (1.8%, Class 1 [C1]). Risk factors associated with C1 and C2 were the absence of a spouse, low educational and economic status, and unstable occupational status. C1 and C2 had more physical and psychological problems than did C3. Prevalence of mental disorders and mental health service use were higher in C1 than in C2.</p><p><strong>Conclusion: </strong>Suicide risk types have different demographic, physical health-related, and mental health-related characteristics. Therefore, a focused and individualized suicide preventive strategy should be implemented.</p>","PeriodicalId":21164,"journal":{"name":"Psychiatry Investigation","volume":"21 11","pages":"1251-1259"},"PeriodicalIF":1.8,"publicationDate":"2024-11-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11611458/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"142751447","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}