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Pre-selection of primary intubation technique is associated with a low incidence of difficult intubation in patients with a BMI of 35 kg/m2 or higher. 预选择初级插管技术与BMI为35 kg/m2或更高的患者插管困难发生率低相关。
Q2 Medicine Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.ezr
Tiberiu Ezri, Ronen Waintrob, Yuri Avelansky, Alexander Izakson, Katia Dayan, Mordechai Shimonov

Background: The incidence of difficult intubation (DI) in obese patients may reach a two-digit figure. No studies have assessed the effect of primary use of special intubation devices on lowering the incidence of DI. We assessed the effect of primary selection of special intubation techniques on the incidence of DI in patients with a BMI of 35 kg/m2 or higher.

Patients and methods: Data from 546 patients with a BMI of 35 kg/m2 or higher who underwent bariatric surgery at Wolfson Medical Center from 2010 through 2014 was retrospectively extracted and analyzed for demographics, predictors of DI and intubation techniques employed. Difficult intubation was defined as the presence of at least one of the followings: laryngoscopy grade 3 or 4, need for >1 laryngoscopy or intubation attempt, need for changing the blade size, failed direct laryngoscopy (DL), difficult or failed videolaryngoscopy (VL-Glidescope), difficult or failed awake fiberoptic intubation (AFOI) and using VL or awake AFOI as rescue airway techniques. Primary intubation techniques were direct DL, VL and AFOI. We correlated the predictors of DI with the actual incidence of DI and with the choice of intubation technique employed.

Results: The overall incidence of DI was 1.6% (1.5% with DL vs. 2.2 with VL + AFOI, p = 0.61). With logistic regression analysis, age was the only significant predictor of DI. Predictors of DI that affected the selection of VL or AFOI as primary intubation tools were Mallampati class 3 or 4, limited neck movement, age, male gender, body mass index and obstructive sleep apnea syndrome.

Conclusion: The lower incidence of DI in our study group may stem from the primary use of special intubation devices, based on the presence of predictors of DI.

背景:肥胖患者插管困难(DI)的发生率可能达到两位数。没有研究评估初次使用特殊插管装置对降低DI发生率的影响。我们评估了主要选择特殊插管技术对BMI为35 kg/m2或更高的患者DI发生率的影响。患者和方法:回顾性提取2010年至2014年在Wolfson医学中心接受减肥手术的546例BMI为35 kg/m2或更高的患者的数据,并对人口统计学、DI预测因素和采用的插管技术进行分析。插管困难被定义为至少存在以下一项:喉镜检查3级或4级,需要1次以上喉镜检查或插管尝试,需要改变叶片大小,直接喉镜检查(DL)失败,视频喉镜检查(VL- glidescope)困难或失败,清醒光纤插管(AFOI)困难或失败,并使用VL或清醒AFOI作为救援气道技术。主要插管技术为直接DL、VL和AFOI。我们将DI的预测因素与DI的实际发生率和所采用的插管技术的选择相关联。结果:DI的总发生率为1.6% (DL为1.5%,VL + AFOI为2.2,p = 0.61)。通过logistic回归分析,年龄是DI的唯一显著预测因子。影响选择VL或AFOI作为主要插管工具的DI预测因子为Mallampati 3级或4级、颈部运动受限、年龄、男性性别、体重指数和阻塞性睡眠呼吸暂停综合征。结论:我们研究组的DI发生率较低可能源于主要使用特殊插管装置,基于DI预测因素的存在。
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引用次数: 7
The Carrico index is the parameter that guides the requirement of oxygen in the postoperative period in patients undergoing head and neck surgery under general anaesthesia: a cross-sectional study. 卡里科指数是指导在全身麻醉下接受头颈部手术的患者术后需氧量的参数:一项横断面研究。
Q2 Medicine Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.crc
Parnandi Bhaskar Rao, Manaswini Mangaraj, Preetam Mahajan, Swagata Tripathy, Neha Singh, Thenmozhi Mani, Sukdev Nayak

Background & aims: Altered lung function and consequent decrease in oxygenation has been linked to the duration of anaesthesia. This necessitates oxygen monitoring and supplementation in the perioperative period. But, evidence is lacking regarding the parameter that guides best the oxygen supplementation in the postoperative period and the parameter that correlates best with the duration of anaesthesia.

Methods: Adult patients scheduled for head & neck surgery under general anaesthesia were recruited. Two radial arterial blood samples one at pre-induction and the other at one hour after extubation were obtained. Primary outcome measures were partial pressure of oxygen (PaO2), saturation (SpO2), arterial oxygen content (CaO2) and Carrico index (PaO2/FiO2) and their relation with duration of anaesthesia.

Results: Data from 112 patients showed a hypoxaemia incidence of 11.6%. We observed a drop in the mean CaO2 and haemoglobin concentration but a rise in the mean PaO2 at recovery. The mean PaO2/FiO2 deteriorated by 225.65 ± 72.46 (95% CI 367.66, 83.64, p = 0.000) at recovery and there was a significant correlation (r = 0.2, p = 0.03) between duration of anaesthesia and decrease in PaO2/FiO2 at recovery with a regression coefficient of 0.27 (95% CI 0.02, 0.50).

Conclusions: The Carrico index was proven to be the best parameter which needs to be monitored perioperatively to detect the alteration in the gaseous exchange in patients undergoing general anaesthesia for head and neck surgery. There is a positive correlation between the decrease in the Carrico index and the duration of anaesthesia especially when it is prolonged beyond 150 minutes.

背景和目的:肺功能的改变和随之而来的氧饱和度下降与麻醉时间的长短有关。因此,有必要在围手术期进行氧气监测和补充。但是,关于术后补氧的最佳指导参数以及与麻醉持续时间最相关的参数,目前还缺乏证据:方法:招募计划在全身麻醉下进行头颈部手术的成人患者。方法:招募计划在全身麻醉下进行头颈部手术的成人患者,分别在麻醉前和拔管后一小时采集两份桡动脉血液样本。主要结果指标为氧分压(PaO2)、饱和度(SpO2)、动脉血氧含量(CaO2)和卡里科指数(PaO2/FiO2)及其与麻醉持续时间的关系:112 名患者的数据显示,低氧血症发生率为 11.6%。我们观察到平均 CaO2 和血红蛋白浓度下降,但恢复时平均 PaO2 上升。复苏时的平均 PaO2/FiO2 下降了 225.65 ± 72.46 (95% CI 367.66, 83.64, p = 0.000),麻醉持续时间与复苏时 PaO2/FiO2 下降之间存在显著相关性(r = 0.2, p = 0.03),回归系数为 0.27 (95% CI 0.02, 0.50):卡里科指数被证明是围术期需要监测的最佳参数,可用于检测头颈部手术全身麻醉患者气体交换的变化。卡里科指数的下降与麻醉时间的长短呈正相关,尤其是当麻醉时间超过 150 分钟时。
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引用次数: 0
Anaesthesiology trainees and their needs: a Romanian perspective. Results from a European survey. 麻醉学培训生及其需求:罗马尼亚视角。这是一项欧洲调查的结果。
Q2 Medicine Pub Date : 2018-04-01 DOI: 10.21454/rjaic.7518.251.prp
Liana Valeanu, Mihai Stefan, Diogo Sobreira Fernandes, Michela Rauseo, Bernardo Matias, Cornelia Predoi, Serban Bubenek, Daniela Filipescu

Anaesthesiology training is going through continuous transformations worldwide. Recent data from a European Survey on anaesthesiology postgraduate trainees and their concerns have been published for the first time, following an initiative by the European Society of Anaesthesiology. Among the responders of this survey, 10.8% were represented by Romanian trainees. The main needs of the Romanian anaesthesiology trainees who completed the questionnaire were, in descending order educational contents/EDAIC, technical skills, exchange programmes, residency workload, residency costs and autonomy transition. Another observation coming from the analysed data is that Romanian anaesthesiologists in training are highly concerned and interested in the field of intensive care medicine. The results also pinpoint to the high costs associated with continuous medical education, leading to a high incentive for workforce migration.

在世界范围内,麻醉学培训正在经历不断的变革。在欧洲麻醉学学会的倡议下,欧洲麻醉学研究生培训生和他们关注的问题调查的最新数据首次公布。在本次调查的应答者中,罗马尼亚学员占10.8%。完成调查表的罗马尼亚麻醉学受训人员的主要需求按教育内容/EDAIC降序排列依次是技术技能、交换方案、住院工作量、住院费用和自主过渡。从分析数据得出的另一个观察结果是,罗马尼亚麻醉师在培训中对重症监护医学领域高度关注和感兴趣。研究结果还指出,与继续医学教育相关的高成本,导致劳动力迁移的高动机。
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引用次数: 0
Postoperative analgesic efficiency of transversus abdominis plane block after ventral hernia repair: a prospective, randomized, controlled clinical trial. 腹疝修补术后经腹平面阻滞的镇痛效果:一项前瞻性、随机、对照临床试验。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.chv
Ion Chesov, Adrian Belîi

Background and aims: Effective postoperative analgesia is a key element in reducing postoperative morbidity, accelerating recovery and avoiding chronic postoperative pain. The aim of this study was to evaluate the effectiveness of ultrasound-guided Transversus Abdominis Plane (TAP) block, performed before surgical incision, in providing postoperative analgesia for patients undergoing open ventral hernia repair under general anaesthesia.

Methods: Seventy elective patients scheduled for open ventral hernia repair surgery under general anaesthesia were divided randomly into two equal groups: Group I received bilateral TAP block performed before surgical incision (n = 35); Group II received systemic postoperative analgesia with parenteral opioid (morphine) alone (n = 35). Postoperatively pain scores at rest and with movement, total morphine consumption and opioid related side effects were recorded.

Results: Postoperative pain scores at rest and mobilization/cough were significantly higher in patients without TAP block (p < 0.05). Mean intraoperative fentanyl consumption was comparable between the two groups: 0.75 ± 0.31 mg in group I (TAP) and 0.86 ± 0.29 mg in group II (MO), p = 0.1299. Patients undergoing preincisional TAP block had reduced morphine requirements during the first 24 hours after surgery, compared to patients from group II, without TAP block (p = 0.0001). There was no difference in the incidence of opioid related side effects (nausea, vomiting) in the both groups during the first 24 postoperative hours.

Conclusion: The use of preincisional ultrasound guided TAP block reduced the pain scores at rest and with movement/cough, opioid consumption and opioid-related side effects after ventral hernia repair when compared with opioid-only analgesia.

背景和目的:有效的术后镇痛是降低术后发病率、加速恢复和避免术后慢性疼痛的关键因素。本研究的目的是评估超声引导下经腹平面(TAP)阻滞在手术切口前对全麻下腹疝开放性修补术患者术后镇痛的效果。方法:选择70例全麻下择期腹疝开放性修补术患者,随机分为两组:1组术前行双侧TAP阻滞(n = 35);II组(35例)术后单纯静脉注射阿片类药物(吗啡)进行全身镇痛。记录术后休息和运动时疼痛评分、吗啡总消耗量和阿片类药物相关副作用。结果:未进行TAP阻断的患者术后休息和活动/咳嗽疼痛评分显著高于对照组(p < 0.05)。两组平均术中芬太尼用量相当:ⅰ组(TAP)为0.75±0.31 mg,ⅱ组(MO)为0.86±0.29 mg, p = 0.1299。与未使用TAP阻断的II组患者相比,手术前接受TAP阻断的患者在术后24小时内吗啡需求减少(p = 0.0001)。两组在术后24小时内阿片类药物相关副作用(恶心、呕吐)的发生率无差异。结论:与单纯阿片类药物镇痛相比,术前超声引导TAP阻滞可降低腹疝修补术后静息、运动/咳嗽疼痛评分、阿片类药物消耗和阿片类药物相关副作用。
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引用次数: 9
Peripheral nerve blocks and postoperative physical therapy: a single-institution survey of physical therapists' preferences and opinions. 周围神经阻滞和术后物理治疗:对物理治疗师的偏好和意见的单一机构调查。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.prh
Robert L McClain, Steven B Porter, Scott M Arnold, Christopher B Robards

Background and aims: Our aim was to ascertain the opinions and preferences of physical therapists with regard to use of peripheral nerve blocks and their impact on the recovery of patients undergoing total joint replacement.

Methods: We conducted an anonymous 24-question survey of 20 full-time inpatient physical therapists at a single tertiary care medical center.

Results: One respondent indicated they never work with patients who have undergone total joint replacement surgery. Nineteen questionnaires were included in the final analysis. Questions omitted by respondents or with write-in answers were not included in the analysis. A majority of respondents (15 [78.9%]) agreed nerve blocks somewhat to greatly improve a patient's pain after total joint replacement surgery. Most respondents answered that nerve blocks somewhat to greatly impede a patient's ability to participate in physical therapy (14 [73.6%]) and make therapy somewhat to very difficult for them as physical therapists (16 [84.2%]). When asked about specific surgeries, (17/18 [94.4%]) and (14/18 [77.8%]) of respondents would prefer that their patients receive periarticular infiltration or no block at all after total knee arthroplasty or total hip arthroplasty, respectively. All respondents (19 [100%]) answered that they thought lower extremity nerve blocks increased a patient's risk of falling after surgery.

Conclusions: According to the physical therapists we surveyed, nerve blocks impede patient recovery and increase the risk of falls, despite their positive impact on pain control. When considering surgery for themselves, therapists indicated they would not want a nerve block.

背景和目的:我们的目的是确定物理治疗师关于使用周围神经阻滞及其对全关节置换术患者康复的影响的意见和偏好。方法:我们对一家三级医疗中心的20名全职住院物理治疗师进行了24个问题的匿名调查。结果:一位受访者表示,他们从未与接受过全关节置换手术的患者一起工作。最终分析包括19份问卷。被调查者遗漏的问题或填写答案的问题不包括在分析中。大多数受访者(15人[78.9%])认为神经阻滞在一定程度上可以极大地改善患者全关节置换术后的疼痛。大多数被调查者认为神经阻滞在一定程度上极大地阻碍了患者参与物理治疗的能力(14例[73.6%]),并使他们作为物理治疗师的治疗变得有些困难(16例[84.2%])。当被问及具体手术时,(17/18[94.4%])和(14/18[77.8%])的受访者分别希望患者在全膝关节置换术和全髋关节置换术后接受关节周浸润或完全不接受阻滞。所有受访者(19人[100%])都认为下肢神经阻滞增加了患者术后跌倒的风险。结论:根据我们调查的物理治疗师,尽管神经阻滞对疼痛控制有积极作用,但它阻碍了患者的恢复并增加了跌倒的风险。当考虑为自己做手术时,治疗师表示他们不想做神经阻滞。
{"title":"Peripheral nerve blocks and postoperative physical therapy: a single-institution survey of physical therapists' preferences and opinions.","authors":"Robert L McClain,&nbsp;Steven B Porter,&nbsp;Scott M Arnold,&nbsp;Christopher B Robards","doi":"10.21454/rjaic.7518.242.prh","DOIUrl":"https://doi.org/10.21454/rjaic.7518.242.prh","url":null,"abstract":"<p><strong>Background and aims: </strong>Our aim was to ascertain the opinions and preferences of physical therapists with regard to use of peripheral nerve blocks and their impact on the recovery of patients undergoing total joint replacement.</p><p><strong>Methods: </strong>We conducted an anonymous 24-question survey of 20 full-time inpatient physical therapists at a single tertiary care medical center.</p><p><strong>Results: </strong>One respondent indicated they never work with patients who have undergone total joint replacement surgery. Nineteen questionnaires were included in the final analysis. Questions omitted by respondents or with write-in answers were not included in the analysis. A majority of respondents (15 [78.9%]) agreed nerve blocks somewhat to greatly improve a patient's pain after total joint replacement surgery. Most respondents answered that nerve blocks somewhat to greatly impede a patient's ability to participate in physical therapy (14 [73.6%]) and make therapy somewhat to very difficult for them as physical therapists (16 [84.2%]). When asked about specific surgeries, (17/18 [94.4%]) and (14/18 [77.8%]) of respondents would prefer that their patients receive periarticular infiltration or no block at all after total knee arthroplasty or total hip arthroplasty, respectively. All respondents (19 [100%]) answered that they thought lower extremity nerve blocks increased a patient's risk of falling after surgery.</p><p><strong>Conclusions: </strong>According to the physical therapists we surveyed, nerve blocks impede patient recovery and increase the risk of falls, despite their positive impact on pain control. When considering surgery for themselves, therapists indicated they would not want a nerve block.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"24 2","pages":"115-124"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642851/pdf/rjaic-24-2-115.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35565097","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 6
Pudendal nerve blocks in men undergoing urethroplasty: a case series. 接受尿道成形术的男性阴部神经阻滞:一个病例系列。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.klv
Arun Kalava, Abby M Pribish, Lucas R Wiegand

The pudendal nerve block (PNB) is widely used for regional anesthesia during obstetric and anorectal procedures, but its role in urologic procedures has not been thoroughly studied. While transvaginal PNB is relatively straightforward, PNB in male patients often requires imaging guidance due to difficulty appreciating anatomic landmarks. We review the PNB and relevant sonoanatomy, and describe its analgesic efficacy in three male patients undergoing urethroplasty for urethral stricture. In this procedure, the patient was placed in lithotomy position, the ischial tuberosity was palpated, and the sacrotuberous ligament and pudendal artery were identified using ultrasound. Ropivacaine was injected medial to the pudendal artery and disappearance of muscle twitch was demonstrated. Two patients reported well-controlled pain at 24 hours postoperatively. One reported perineal pain requiring additional analgesia. All patients were discharged on postoperative day 1 without complications. Ultrasound-guided PNB provides safe and reasonably effective pain control to male patients undergoing urologic procedures.

阴部神经阻滞(PNB)在产科和肛肠手术中广泛用于区域麻醉,但其在泌尿外科手术中的作用尚未得到深入研究。虽然经阴道PNB相对简单,但由于难以识别解剖标志,男性患者的PNB通常需要影像学指导。我们回顾了PNB和相关的超声解剖,并描述了其在3例男性尿道狭窄行尿道成形术中的镇痛效果。手术中,患者取取取石位,触诊坐骨结节,超声检查骶结节韧带和阴部动脉。罗哌卡因注射于阴部动脉内侧,肌痉挛消失。2例患者术后24小时疼痛控制良好。一例报告会阴部疼痛需要额外的镇痛。所有患者均于术后第1天出院,无并发症。超声引导下的PNB为接受泌尿外科手术的男性患者提供安全、合理有效的疼痛控制。
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引用次数: 8
A cross-sectional survey of anaesthesia-related expectations amongst patients awaiting upper limb trauma surgery. 等待上肢创伤手术患者麻醉相关期望的横断面调查。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.bdo
Brian Declan O'Donnell, Gabriella Iohom

Background and aims: Little is known regarding patients' anaesthesia-related expectations when presenting for upper limb trauma surgery.

Methods: We conducted a prospective cross-sectional survey exploring prior anaesthetic experience, anaesthesia-related knowledge, anaesthesia expectations, the preoperative visit and factors likely to influence anaesthesia choice. The survey was completed by 192 patients.

Results: Anaesthetists were identified as doctors by 52%; 53% were unaware of their planned anaesthesia; 58% indicated likely acceptance of regional anaesthesia. Information regarding anaesthesia originated mostly from surgeons (65%); 93% had not seen an anaesthetist at the time of the survey. Most believed anaesthesia involved 'going to sleep' (82%) and 71% expected to receive general anaesthesia. The preoperative anaesthesia visit was rated as important by 65% of patients. 78% indicated that provision of information would increase the likelihood of accepting regional anaesthesia. Reducing postoperative pain and nausea would influence 80% in choosing a regional technique.

Conclusion: A knowledge deficit exists regarding anaesthesia modalities for upper limb trauma surgery.

背景和目的:对于上肢创伤手术患者的麻醉相关期望知之甚少。方法:采用前瞻性横断面调查方法,探讨患者的麻醉经验、麻醉相关知识、麻醉预期、术前访视情况以及影响麻醉选择的因素。该调查由192名患者完成。结果:52%的人认为麻醉师是医生;53%的人不知道他们的麻醉计划;58%的人表示可能接受局部麻醉。关于麻醉的信息主要来自外科医生(65%);93%的人在调查时没有见过麻醉师。大多数人认为麻醉涉及“入睡”(82%),71%的人期望接受全身麻醉。65%的患者认为术前麻醉访视很重要。78%的人表示,提供信息会增加接受局部麻醉的可能性。减少术后疼痛和恶心对选择局部手术有80%的影响。结论:上肢外伤手术麻醉方式存在知识缺陷。
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引用次数: 1
Measurements of oxygen saturation of brain, liver and heart areas in the supine and sitting position using near infrared spectrophotometry. 用近红外分光光度法测量仰卧位和坐位时脑、肝和心脏区域的氧饱和度。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.fss
Athanasia Tsaroucha, Anteia Paraskeva, Argyro Fassoulaki

Background and aims: Regional oxygen saturation (rSO2) monitoring of the brain by near-infrared spectroscopy (NIRS) has been mainly used during carotid endarterectomy. The present study was conducted in volunteers and investigates the rSO2 values of the brain, heart and liver tissue as assessed by NIRS in the supine and the sitting position.

Methods: After obtaining written informed consent from forty-nine healthy volunteers, rSO2 values were recorded in the heart and liver areas in the supine and the sitting position, while simultaneously the rSO2 values of the brain.

Results: The rSO2 brain values in the supine and the sitting position were 69 ± 6.0 and 66 ± 6.1 respectively (p = 0.0001). The rSO2 values in the supine and the sitting position were 76 ± 10.5 and 79 ± 6.7 for the heart (p > 0.05) and 85 ± 6.8 and 82 ± 7.2 for the liver, (p = 0.007). Heart rSO2 values were higher than the brain rSO2 values in both the supine (76 ± 10.4 versus 69 ± 6.6; p = 0.0001) and the sitting position (79 ± 6.7 versus 66 ± 6.1; p = 0.0001). The liver rSO2 values were also higher than the brain rSO2 values in the supine (85 ± 6.8 versus 69 ± 6.0; p = 0.0001) and in the sitting position (82 ± 7.2 versus 66 ± 5.7; p = 0.0001). Arterial blood pressure and arterial oxygen saturation (SpO2) did not differ between the two positions but the heart rate was higher in the sitting position (p = 0.030).

Conclusions: We conclude that brain and liver (but not heart) rSO2 values are higher in the supine than sitting position. Additionally, NIRS may be used to assess oxygenation of the heart and liver.

背景与目的:近红外光谱(NIRS)监测脑区域氧饱和度(rSO2)主要用于颈动脉内膜切除术。本研究是在志愿者中进行的,通过近红外光谱(NIRS)对仰卧和坐位时大脑、心脏和肝脏组织的rSO2值进行评估。方法:49名健康志愿者在获得书面知情同意后,分别在仰卧位和坐位记录心脏和肝脏区域的rSO2值,同时记录大脑的rSO2值。结果:仰卧位和坐位rSO2脑值分别为69±6.0和66±6.1 (p = 0.0001)。平卧位和坐位的rSO2分别为心脏76±10.5和79±6.7 (p > 0.05),肝脏85±6.8和82±7.2 (p = 0.007)。仰卧两组心脏rSO2值均高于脑rSO2值(76±10.4 vs 69±6.6);P = 0.0001)和坐姿(79±6.7 vs 66±6.1;P = 0.0001)。仰卧位时肝脏rSO2值也高于脑rSO2值(85±6.8 vs 69±6.0);P = 0.0001)和坐姿(82±7.2 vs 66±5.7;P = 0.0001)。动脉血压和动脉血氧饱和度(SpO2)在两种体位之间无显著差异,但心率在坐姿时较高(p = 0.030)。结论:我们得出的结论是,仰卧位的大脑和肝脏(而不是心脏)的rSO2值高于坐位。此外,近红外光谱可用于评估心脏和肝脏的氧合。
{"title":"Measurements of oxygen saturation of brain, liver and heart areas in the supine and sitting position using near infrared spectrophotometry.","authors":"Athanasia Tsaroucha,&nbsp;Anteia Paraskeva,&nbsp;Argyro Fassoulaki","doi":"10.21454/rjaic.7518.242.fss","DOIUrl":"https://doi.org/10.21454/rjaic.7518.242.fss","url":null,"abstract":"<p><strong>Background and aims: </strong>Regional oxygen saturation (rSO<sub>2</sub>) monitoring of the brain by near-infrared spectroscopy (NIRS) has been mainly used during carotid endarterectomy. The present study was conducted in volunteers and investigates the rSO<sub>2</sub> values of the brain, heart and liver tissue as assessed by NIRS in the supine and the sitting position.</p><p><strong>Methods: </strong>After obtaining written informed consent from forty-nine healthy volunteers, rSO<sub>2</sub> values were recorded in the heart and liver areas in the supine and the sitting position, while simultaneously the rSO<sub>2</sub> values of the brain.</p><p><strong>Results: </strong>The rSO<sub>2</sub> brain values in the supine and the sitting position were 69 ± 6.0 and 66 ± 6.1 respectively (p = 0.0001). The rSO<sub>2</sub> values in the supine and the sitting position were 76 ± 10.5 and 79 ± 6.7 for the heart (p > 0.05) and 85 ± 6.8 and 82 ± 7.2 for the liver, (p = 0.007). Heart rSO<sub>2</sub> values were higher than the brain rSO<sub>2</sub> values in both the supine (76 ± 10.4 versus 69 ± 6.6; p = 0.0001) and the sitting position (79 ± 6.7 versus 66 ± 6.1; p = 0.0001). The liver rSO<sub>2</sub> values were also higher than the brain rSO2 values in the supine (85 ± 6.8 versus 69 ± 6.0; p = 0.0001) and in the sitting position (82 ± 7.2 versus 66 ± 5.7; p = 0.0001). Arterial blood pressure and arterial oxygen saturation (SpO<sub>2</sub>) did not differ between the two positions but the heart rate was higher in the sitting position (p = 0.030).</p><p><strong>Conclusions: </strong>We conclude that brain and liver (but not heart) rSO<sub>2</sub> values are higher in the supine than sitting position. Additionally, NIRS may be used to assess oxygenation of the heart and liver.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"24 2","pages":"101-106"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642848/pdf/rjaic-24-2-101.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35564167","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Respiratory events with sugammadex vs. neostigmine following laparoscopic sleeve gastrectomy: a prospective pilot study assessing neuromuscular reversal strategies. 腹腔镜袖胃切除术后使用糖玛德与新斯的明的呼吸事件:一项评估神经肌肉逆转策略的前瞻性先导研究。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.evr
Shmuel Evron, Yuri Abelansky, Tiberiu Ezri, Alexander Izakson

Abdominal surgery in obese patients may be associated with pulmonary morbidity, and mortality. Some patients may arrive in the PACU with residual paralysis. The purpose of this study was to find out if there was an association between the type of muscle relaxant reversal agent and the development of postoperative respiratory events in patients undergoing laparoscopic sleeve gastrectomy surgery.

Methods: From September 2012 to February 2013, in a prospective randomized pilot study, two different muscle relaxant reversal agents were administered at the end of surgery in 57 patients undergoing laparoscopic sleeve gastrectomy: sugammadex 2 mg/kg (32 patients) vs. neostigmine 2.5 mg (25 patients). We compared the occurrence of early and late respiratory events/complications by the type of reversal agent. Postoperative respiratory rate, oxyhemoglobin saturation (SpO2), number of patients with SpO2 lower than 95% in PACU, the minimum value of SpO2 in PACU, train-of four counts (TOF) before reversal, unexpected ICU admissions, duration of hospitalization and incidence of reintubation were recorded.

Results: SpO2 in the PACU was significantly lower in the neostigmine group - 95.80 (± 0.014)) vs. in sugammadex group - 96.72 (± 0.011) (p < 0.01), despite a lower TOF count measured in the sugammadex group before reversal, meaning a deeper level of residual relaxation in this group before the administration of the reversal agent (2.53 ± 0.98 vs. 3.48 ± 0.58 p < 0.01). Also, the minimal SpO2 was significantly lower in the PACU in the neostigmine group: 93% vs. 94% (p = 0.01). Respiratory rates were not different. After the administration of reversal, both groups had TOF counts of 4 with no fade assessed visually. There were no postoperative respiratory events or complications.

Conclusions: The use of sugammadex (as compared to neostigmine) as a reversal agent following laparoscopic sleeve gastrectomy surgery was associated with higher postoperative SpO2 despite the lower TOF count before the administration of reversal agent. Despite the statistical difference in SpO2, its clinical importance seems to be minimal. The lack of difference in the other measured variables may stem from the small number of patients studied (pilot).

肥胖患者的腹部手术可能与肺部发病率和死亡率有关。有些患者到达PACU时可能伴有残瘫。本研究的目的是探讨肌肉松弛剂逆转剂的类型与腹腔镜胃切除术患者术后呼吸事件的发生之间是否存在关联。方法:2012年9月至2013年2月,在一项前瞻性随机先导研究中,57例腹腔镜袖胃切除术患者在手术结束时给予两种不同的肌肉松弛逆转剂:sugammadex 2 mg/kg(32例)vs新斯的明2.5 mg(25例)。我们比较了不同类型逆转剂的早期和晚期呼吸事件/并发症的发生率。记录术后呼吸率、血氧饱和度(SpO2)、PACU中SpO2低于95%的患者数、PACU中SpO2的最小值、逆转前四次计数(TOF)、意外入住ICU、住院时间、再插管发生率。结果:新斯的明组PACU SpO2(95.80(±0.014))明显低于sugammadex组(96.72(±0.011))(p < 0.01),尽管在逆转前,sugammadex组的TOF计数较低,这意味着在给予逆转剂之前,该组的残余松弛程度更深(2.53±0.98比3.48±0.58 p < 0.01)。此外,新斯的明组PACU的最小SpO2也显著降低:93%比94% (p = 0.01)。呼吸频率没有差别。给予逆转治疗后,两组TOF计数均为4,目测无衰退。术后无呼吸事件或并发症。结论:腹腔镜袖胃切除术后使用sugammadex(与新斯的明相比)作为逆转剂与术后SpO2升高相关,尽管给予逆转剂前TOF计数较低。尽管SpO2有统计学差异,但其临床重要性似乎很小。其他测量变量缺乏差异可能源于研究的患者数量较少(试点)。
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引用次数: 12
Perioperative Patient Blood Management Programme. Multidisciplinary recommendations from the Patient Blood Management Initiative Group. 围手术期患者血液管理计划。来自患者血液管理倡议小组的多学科建议。
Q2 Medicine Pub Date : 2017-10-01 DOI: 10.21454/rjaic.7518.242.fil
Daniela Filipescu, Răzvan Bănăţeanu, Mircea Beuran, Traean Burcoş, Dan Corneci, Dan Cristian, Mircea Diculescu, Alina Dobrotă, Gabriela Droc, Dănuţ Isacoff, Doina Goşa, Ioana Grinţescu, Anca Lupu, Liliana Mirea, Corina Posea, Oana Stanca, Mihai Ştefan, Dana Tomescu, Cristina Tudor, Daniela Ungureanu, Gabriel Mircescu

Patients with untreated anaemia or iron deficiency who undergo surgical procedures have an increased risk for mortality and morbidity. Patient Blood Management programmes address this issue worldwide and try to improve patient outcomes through a complex set of measures targeting anaemia correction, minimisation of bleeding and improvement of anaemia tolerance, in all phases of perioperative care. The Patient Blood Management Initiative Group is a multidisciplinary team of physicians from specialties including anaesthesiology, nephrology, surgery, orthopaedics, haematology, gastroenterology and transfusion medicine. The team has elaborated ten recommendations, divided into five categories, in order to implement a Patient Blood Management programme in Romania, using the most recent and relevant evidence. The document was discussed during three meetings which took place during October 2016 and May 2017 and the result was modified and updated via e-mail.

未经治疗的贫血或缺铁患者接受外科手术后,死亡率和发病率的风险增加。患者血液管理规划在世界范围内解决了这一问题,并试图通过在围手术期护理的所有阶段采取一系列针对贫血矫正、出血最小化和改善贫血耐受性的复杂措施来改善患者的预后。患者血液管理倡议小组是一个多学科的医生团队,包括麻醉学、肾病学、外科、骨科、血液学、胃肠病学和输血医学等专业。该小组利用最新和相关的证据,制定了十项建议,分为五类,以便在罗马尼亚实施患者血液管理规划。该文件在2016年10月至2017年5月举行的三次会议上进行了讨论,结果通过电子邮件进行了修改和更新。
{"title":"Perioperative Patient Blood Management Programme. Multidisciplinary recommendations from the <i>Patient Blood Management Initiative Group</i>.","authors":"Daniela Filipescu,&nbsp;Răzvan Bănăţeanu,&nbsp;Mircea Beuran,&nbsp;Traean Burcoş,&nbsp;Dan Corneci,&nbsp;Dan Cristian,&nbsp;Mircea Diculescu,&nbsp;Alina Dobrotă,&nbsp;Gabriela Droc,&nbsp;Dănuţ Isacoff,&nbsp;Doina Goşa,&nbsp;Ioana Grinţescu,&nbsp;Anca Lupu,&nbsp;Liliana Mirea,&nbsp;Corina Posea,&nbsp;Oana Stanca,&nbsp;Mihai Ştefan,&nbsp;Dana Tomescu,&nbsp;Cristina Tudor,&nbsp;Daniela Ungureanu,&nbsp;Gabriel Mircescu","doi":"10.21454/rjaic.7518.242.fil","DOIUrl":"https://doi.org/10.21454/rjaic.7518.242.fil","url":null,"abstract":"<p><p>Patients with untreated anaemia or iron deficiency who undergo surgical procedures have an increased risk for mortality and morbidity. Patient Blood Management programmes address this issue worldwide and try to improve patient outcomes through a complex set of measures targeting anaemia correction, minimisation of bleeding and improvement of anaemia tolerance, in all phases of perioperative care. The Patient Blood Management Initiative Group is a multidisciplinary team of physicians from specialties including anaesthesiology, nephrology, surgery, orthopaedics, haematology, gastroenterology and transfusion medicine. The team has elaborated ten recommendations, divided into five categories, in order to implement a Patient Blood Management programme in Romania, using the most recent and relevant evidence. The document was discussed during three meetings which took place during October 2016 and May 2017 and the result was modified and updated via e-mail.</p>","PeriodicalId":21279,"journal":{"name":"Romanian journal of anaesthesia and intensive care","volume":"24 2","pages":"139-157"},"PeriodicalIF":0.0,"publicationDate":"2017-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5642854/pdf/rjaic-24-2-139.pdf","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"35565100","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 10
期刊
Romanian journal of anaesthesia and intensive care
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