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Indoor Location Technology for Managing Elective Surgery Patients in Hospitals. 医院择期手术患者管理的室内定位技术。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253813-en
Ibtisam Hamzeh Mohammad Husein Shalabi, Laura Maria César Schiesari

Introduction: With the increase in healthcare spending, efficient resource management in surgical hospitals has become essential, especially with regard to managing patient flow to avoid delays. Therefore, tools that can provide instant visibility of the patients location in each sector can be of great value in choices about resource allocation. Therefore, the objective of this study was to evaluate the applicability of indoor location technology in a hospital environment.

Methods: Prospective study, carried out from February to March 2024, in a private surgical hospital, with tertiary structure, specialized in the care of elderly patients. The records of the path of each elective patient were mapped from their arrival to the moment of their discharge, as well as the activities of the professionals involved, through an indoor Bluetooth location device.

Results: 320 patients were analyzed, with an average stay time in the reception of 25 minutes and the time in the preoperative preparation unit of 107 minutes. Urology, mastology, and oncology surgeries represented 50% of the case series. The median transport time for these patients was 19 minutes. Reception (75.6%) and nursing admission (72.5%) were the sectors with the highest percentage of correct execution. The delay rate was 89.9% in the first time slot, and in subsequent times the delay was significantly lower (70.1%) compared to the time scheduled on the map.

Conclusion: Indoor location technology has applicability when used in the intra-hospital environment in the management of surgical patients, facilitating the identification of bottlenecks and their causes.

导言:随着医疗保健支出的增加,外科医院有效的资源管理变得至关重要,特别是在管理患者流量以避免延误方面。因此,能够提供每个部门患者位置的即时可见性的工具在选择资源分配时具有很大的价值。因此,本研究的目的是评估室内定位技术在医院环境中的适用性。方法:前瞻性研究,于2024年2月- 3月在一家三级结构的专科老年外科医院进行。通过室内蓝牙定位设备,绘制了每位选择性患者从到达到出院的路径记录,以及相关专业人员的活动。结果:分析320例患者,平均在接待处停留时间为25分钟,在术前准备单元停留时间为107分钟。泌尿外科、乳腺外科和肿瘤外科占病例总数的50%。这些患者的中位转运时间为19分钟。接待处(75.6%)和护理住院(72.5%)是正确执行率最高的部门。在第一个时隙的延迟率为89.9%,在随后的时间延迟率明显低于地图上计划的时间(70.1%)。结论:室内定位技术在医院内环境下对外科患者的管理具有适用性,便于发现瓶颈及其原因。
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引用次数: 0
Quality of life assessment in patients undergoing partial and total thyroidectomy. 甲状腺部分和全切除术患者的生活质量评估。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253870-en
Pedro Henrique Serra Carvalho Dos Santos, Roberta Zambo Galafassi, Giulia Fernandes Manhães Rodrigues Lopes, Leiziane Assunção Alves Guimarães, Fatima Rosalia Hartelsberger Bobadilla, Inês Nobuko Nishimoto, Rogério Aparecido Dedivitis

Introduction: Thyroidectomy, which consists of partial or total removal of the thyroid gland, is a commonly performed surgery to treat various thyroid diseases. In recent years, the trend has been toward partial thyroidectomies, due to their association with lower complication rates and the fact that they may be sufficient for adequate management.

Objective: To evaluate the impact of partial and total thyroidectomy on quality of life.

Methods: This study used the ThyPro questionnaire, which assesses the quality of life of patients with thyroid disorders, to investigate the impact of different thyroidectomy approaches on patients' quality of life.

Results: The postoperative complications were transient unilateral recurrent nerve paralysis (6.5%) and transitory hypoparathyroidism (22.4%). The quality of life outcomes after thyroidectomy were favorable. The extension of the thyroidectomy did not present statistical difference (p = 0.982). Significantly lower scores were associated with female gender and neck dissection.

Conclusion: Quality of life scores were high, with lower scores among women and neck dissection.

简介:甲状腺切除术包括部分或全部切除甲状腺,是治疗各种甲状腺疾病的常用手术。近年来,由于甲状腺部分切除术的并发症发生率较低,而且可能足以进行适当的治疗,因此趋势是甲状腺部分切除术。目的:探讨甲状腺部分切除术和甲状腺全切除术对患者生活质量的影响。方法:本研究采用甲状腺功能障碍患者生活质量评估问卷ThyPro,探讨不同甲状腺切除术方式对患者生活质量的影响。结果:术后并发症为一过性单侧复发性神经麻痹(6.5%)和一过性甲状旁腺功能低下(22.4%)。甲状腺切除术后的生活质量良好。甲状腺切除的范围差异无统计学意义(p = 0.982)。较低的评分与女性和颈部解剖有关。结论:患者的生活质量评分较高,女性患者和颈部夹层患者的生活质量评分较低。
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引用次数: 0
Robotic surgery in the interior of Brazil: Is it possible? 机器人手术在巴西内陆:可能吗?
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253838-en
Jorge Roberto Mercante-Carlotto, Petra Mistura Arcoverde Cavalcanti, Ana Luísa Dos Santos Carregosa, Eduarda Leitzke, Lara Fabian DE Moura, Milena DE Almeida DA Motta, Nicole Mombelli Mattei, Rodrigo Guerra-Casarin, Tami Zang Crestani

Introduction: Robotic surgery has been used in the treatment of various surgical diseases due to its precision and satisfactory outcomes. This study aims to describe the profile of patients undergoing robotic surgery at the Hospital de Clínicas de Passo Fundo and analyze the variables related to the procedure and its outcomes.

Methods: A total of 215 medical records of patients who underwent robotic surgery at the Regional Robotic Surgery Center of the Hospital de Clínicas de Passo Fundo were reviewed, from the start of the program in 2023 until March 2024. Sex, age, comorbidities, and perioperative and postoperative data were evaluated.

Results: The sample had a predominance of males (73.5%). The average age was 61 years. Systemic arterial hypertension was the most prevalent comorbidity (43.7%). Regarding operative time, the first six months had a higher median total time (300 minutes) compared to the last six months (245 minutes) with p≤0.001.

Conclusion: The implementation of a robotic surgery center in the interior of Brazil proved to be feasible, with favorable outcomes, progressive reductions in surgical times, and regional benefits by expanding access to cutting-edge technologies.

机器人手术以其精确性和令人满意的效果被广泛应用于各种外科疾病的治疗中。本研究旨在描述在医院de Clínicas de Passo Fundo接受机器人手术的患者的概况,并分析与手术及其结果相关的变量。方法:回顾了从2023年项目开始到2024年3月期间,在Clínicas de Passo Fundo医院区域机器人手术中心接受机器人手术的患者的215份医疗记录。评估性别、年龄、合并症、围手术期和术后数据。结果:样本以男性为主(73.5%)。平均年龄为61岁。全身性动脉高血压是最常见的合并症(43.7%)。关于手术时间,前6个月的中位总时间(300分钟)高于后6个月(245分钟),p≤0.001。结论:在巴西内陆地区实施机器人手术中心被证明是可行的,效果良好,手术时间逐步减少,并通过扩大尖端技术的获取而获得区域效益。
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引用次数: 0
Can viable bacteria be present in the surface of ready-to-use surgical instruments? 手术器械表面是否存在活菌?
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253852-en
Carlos Roberto DE Oliveira Sauer, Francisco Hideo Aoki, Rogério Hakio Kuboyama, Márcia Regina Suzuki DE Lima, Inês Helena DE Barros Leal Saraiva, Cely Barreto Silva, Francisco Américo Fernandes Neto, Mauro José DA Costa Salles

Introduction: biofilm is considered a challenge regarding treatment of chronic diseases and, after a detailed observation of cleaning and sterilization processes, it is considered could be a threat to sterility of surgical instruments that are "ready to use". Colored plastic bands (color coding tapes for marking surgical instruments) are frequently used to assist in the assembly of surgical instrument boxes. These bands form a lifting, which makes cleaning the material difficult. Epidemiological data regarding the frequency of surgical site infection in Brazil (up to 24% in Center-West Region) may be suggestive of contamination of operative instruments. The objective of this study is to answer the question: is there a risk of biofilm on ready-to-use surgical instruments?

Methods: narrative literature review.

Results: 296 articles were found and a total of 163 were selected for detailed reading, of which 78 were included. During the survey, four knowledge domains were outlined: microbiology, pathophysiology/epidemiology, technology and management. This review pointed out the risk of the bacterial load prior to autoclaving, the efficiency of the sterilization method regarding the presence of microscopic soils and, under current conditions, the ability of the Material and Sterilization Centers to ensure adequate cleaning.

Conclusion: after working extensively to associate all the collected information, there is a considerable probability of bacterial biofilms in ready-to-use surgical instruments and, therefore further research in this field of microbiology is justified, with an emphasis on improving process quality indicators, giving the potential impact on reduction of surgical site infection rates.

导言:生物膜被认为是慢性病治疗方面的一个挑战,在对清洁和灭菌过程进行详细观察后,认为它可能对“准备使用”的手术器械的无菌性构成威胁。彩色塑料带(标记手术器械的彩色编码带)经常用于辅助手术器械盒的组装。这些带形成一个提升,这使得清洗材料困难。关于巴西手术部位感染频率的流行病学数据(在中西部地区高达24%)可能提示手术器械污染。本研究的目的是回答这样一个问题:即用型手术器械是否存在生物膜的风险?方法:叙述文献法。结果:共检索到296篇文章,筛选出163篇进行详细阅读,其中78篇被纳入。在调查中,概述了四个知识领域:微生物学,病理生理学/流行病学,技术和管理。这篇综述指出了高压灭菌前细菌负荷的风险,灭菌方法在存在微观土壤时的效率,以及在当前条件下,材料和灭菌中心确保充分清洁的能力。结论:在对收集到的所有信息进行广泛关联后,现成手术器械中存在细菌生物膜的可能性相当大,因此在微生物学领域的进一步研究是合理的,重点是提高工艺质量指标,对降低手术部位感染率有潜在的影响。
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引用次数: 0
A paradigm shift in Diastasis Recti surgery: The Bikini-line robotic approach. 直肠移位手术的范式转变:比基尼线机器人方法。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20243846-en
Andre Luiz Gioia Morrell, Allan Gioia Morrell, Alexander Charles Morrell Junior, Alexander Charles Morrell

Introduction: diastasis recti surgery has been known worldwide for open surgical techniques involving significant tissue manipulation, skin flap and larger incisions. Traditional methods typically required extended recovery times and posed higher risks of complications and scarring issues. The advent of robotic-assisted surgery has revolutionized the treatment paradigm for abdominal wall defects and its remarkable outcomes encouraged expanding its applications towards diastasis recti pathologies. Better visualization and more ergonomic instruments foster a minimal scarring procedure, allowing surgeons to improve aesthetic and recovery outcomes following diastasis recti correction in a posterior approach. This article describes a robotic surgical technique and results to an unprecedented approach, putting its form of treatment into another perspective.

Technical report: a step-by-step guided technique of this novel technique is described using detailed port placement and figures to assure optimal aesthetic and functional outcomes whenever acting in minimally invasive diastasis recti repair with the da Vinci platform.

Conclusion: The described technique reveals a hidden minimal incisions procedure avoiding skin flaps, scarring issues, and minimizing wound morbidity. Through a step-by-step guide, this report establishes an unprecedent technique description transforming the diastasis recti surgery scenario and its aesthetic outcomes with a safe minimally invasive surgery.

简介:直肠转移手术以开放性手术技术闻名于世,涉及重要的组织操作、皮瓣和更大的切口。传统的方法通常需要较长的恢复时间,并带来更高的并发症和疤痕问题的风险。机器人辅助手术的出现彻底改变了腹壁缺陷的治疗模式,其显著的效果鼓励扩大其在转移性直肠病变中的应用。更好的视觉效果和更符合人体工程学的器械可使手术瘢痕最小化,使外科医生能够在后路手术中改善椎体分离矫正后的美观和恢复效果。本文描述了一种前所未有的机器人手术技术和结果,将其治疗形式置于另一个角度。技术报告:这项新技术的一步一步的指导技术被描述为使用详细的端口放置和数字,以确保最佳的美学和功能结果,无论何时使用达芬奇平台进行微创移位直肠修复。结论:所描述的技术揭示了一种隐藏的最小切口手术,避免了皮瓣,瘢痕问题,并将伤口发病率降到最低。通过一步一步的指导,本报告建立了一个前所未有的技术描述,用安全的微创手术改变了直肠移位手术的场景和美学结果。
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引用次数: 0
Factors associated with fasting time in pediatric patients hospitalized for surgery. 儿科手术住院患者禁食时间的相关因素
Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253889-en
Laura Naspitz, Fernanda Luísa Ceragioli Oliveira, Renato Lopes DE Souza, Tulio Konstantyner

Introduction: Shorter fasting periods before and after surgery have been associated with better postoperative recovery and lower morbidity and mortality. However, it is not always possible to achieve current recommendations in pediatric practice. Therefore, it is essential to study fasting time and its associated factors to implement better care strategies.

Methods: Cohort of 284 pediatric patients admitted for surgery between 2020-2021, Hospital São Paulo, Brazil. Data was collected through interviews and medical records. Simple and multiple linear models and logistic regression models were adjusted to study the associations.

Results: All preoperative patients fasted for a prolonged period and most resumed feeding 6 hours after the end of anesthesia. Preoperative fasting time was shorter for elective surgery than for urgent surgery (p=0.025). Factors associated with a longer preoperative fasting time (minutes) were: older age in years (ß=10; 95% CI=5.2-14.8) and history of previous surgery (ß=76.6; 95% CI=28.0-125.1). Factors associated with postoperative fasting time longer than 6 hours were: no immediate postoperative care in the surgical ward (OR=6.05; 95%CI=2.25-16.22), presence of complications during surgery (OR=3. 53; 95%CI=1.19-10.47), major operation size (OR=3.85; 95%CI=1.49-9.93), abdominal surgery (OR=36.52; 95%CI=13.48-98.91) and vomiting in the first 24 hours (OR=3.44; 95%CI=1.54-7.69).

Conclusion: There are potentially modifiable factors associated with longer fasting times. Education and organization of the healthcare team regarding patient characteristics, care dynamics, and clinical complications may contribute to greater optimization of fasting times in pediatric surgical patients.

前言:手术前后较短的禁食时间与更好的术后恢复和较低的发病率和死亡率相关。然而,在儿科实践中并不总是能够达到目前的建议。因此,研究禁食时间及其相关因素对实施更好的护理策略至关重要。方法:对巴西圣保罗医院2020-2021年间住院的284例儿科患者进行队列研究。通过访谈和医疗记录收集数据。调整简单和多元线性模型以及逻辑回归模型来研究相关性。结果:术前患者禁食时间均较长,麻醉结束后6小时恢复进食。择期手术术前禁食时间短于急诊手术(p=0.025)。术前禁食时间(分钟)较长的相关因素是:年龄较大(10岁;95% CI=5.2-14.8)和既往手术史(ß=76.6; 95% CI=28.0-125.1)。术后禁食时间超过6小时的相关因素有:外科病房未立即接受术后护理(OR=6.05; 95%CI=2.25-16.22)、手术中出现并发症(OR=3)。53个;95%CI=1.19 ~ 10.47)、大手术规模(OR=3.85; 95%CI=1.49 ~ 9.93)、腹部手术(OR=36.52; 95%CI=13.48 ~ 98.91)和前24小时呕吐(OR=3.44; 95%CI=1.54 ~ 7.69)。结论:有可能改变的因素与较长的禁食时间有关。对医疗团队进行有关患者特征、护理动态和临床并发症的教育和组织,可能有助于更好地优化儿科外科患者的禁食时间。
{"title":"Factors associated with fasting time in pediatric patients hospitalized for surgery.","authors":"Laura Naspitz, Fernanda Luísa Ceragioli Oliveira, Renato Lopes DE Souza, Tulio Konstantyner","doi":"10.1590/0100-6991e-20253889-en","DOIUrl":"10.1590/0100-6991e-20253889-en","url":null,"abstract":"<p><strong>Introduction: </strong>Shorter fasting periods before and after surgery have been associated with better postoperative recovery and lower morbidity and mortality. However, it is not always possible to achieve current recommendations in pediatric practice. Therefore, it is essential to study fasting time and its associated factors to implement better care strategies.</p><p><strong>Methods: </strong>Cohort of 284 pediatric patients admitted for surgery between 2020-2021, Hospital São Paulo, Brazil. Data was collected through interviews and medical records. Simple and multiple linear models and logistic regression models were adjusted to study the associations.</p><p><strong>Results: </strong>All preoperative patients fasted for a prolonged period and most resumed feeding 6 hours after the end of anesthesia. Preoperative fasting time was shorter for elective surgery than for urgent surgery (p=0.025). Factors associated with a longer preoperative fasting time (minutes) were: older age in years (ß=10; 95% CI=5.2-14.8) and history of previous surgery (ß=76.6; 95% CI=28.0-125.1). Factors associated with postoperative fasting time longer than 6 hours were: no immediate postoperative care in the surgical ward (OR=6.05; 95%CI=2.25-16.22), presence of complications during surgery (OR=3. 53; 95%CI=1.19-10.47), major operation size (OR=3.85; 95%CI=1.49-9.93), abdominal surgery (OR=36.52; 95%CI=13.48-98.91) and vomiting in the first 24 hours (OR=3.44; 95%CI=1.54-7.69).</p><p><strong>Conclusion: </strong>There are potentially modifiable factors associated with longer fasting times. Education and organization of the healthcare team regarding patient characteristics, care dynamics, and clinical complications may contribute to greater optimization of fasting times in pediatric surgical patients.</p>","PeriodicalId":21454,"journal":{"name":"Revista do Colegio Brasileiro de Cirurgioes","volume":"52 ","pages":"e20253889"},"PeriodicalIF":0.0,"publicationDate":"2025-12-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC12685242/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"145794969","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Healthcare-Associated Infections in a Burn Treatment Unit. 烧伤治疗室医疗保健相关感染
Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253882-en
Marcelo Mourão, Marília Baeninger, Thaysa Sobral Antonelli, Daniela Vieira DA Silva Escudero, Maria Claudia Stockler DE Almeida, Alfredo Gragnani

Introduction: Severe burns significantly weaken the immune system and disrupt the skin's natural barrier, which increases the likelihood of healthcare-associated infections (HAIs) and raises the risk of mortality.

Methods: Based on CDC criteria, this study retrospectively examines the incidence of HAIs in burn patients hospitalized at a university hospital in São Paulo, Brazil, over five years from 2018 to 2022.

Results: 536 patients were treated during this time, with 130 HAIs recorded in 88 individuals. The average age of the patients was 41 years, and the mean total body surface area (TBSA) affected by burns was 20.4%. The primary causes of burns were flammable liquids (39.7%), electrical injuries (25%), and scalds from heated liquids (14.8%). Burn wound infections were the most frequent HAI (51.5%), followed by bloodstream infections (13.8%), urinary tract infections (13.1%), and ventilator-associated pneumonia (10.7%). Regarding microbiological findings, 141 microorganisms were isolated, with gram-negative bacteria making up 71.6% of the total, gram-positive bacteria accounting for 21.2%, and fungi representing 7.1%. In three cases, no microorganism was identified. The mortality rate among these patients was 13,6%.

Conclusion: Notably, the predominance of gram-negative bacteria in this population, responsible for more than 70% of infections, contrasts with findings from other studies. The findings highlight the importance of infection control to reduce morbidity and mortality in this vulnerable population.

严重烧伤会显著削弱免疫系统,破坏皮肤的天然屏障,从而增加医疗保健相关感染(HAIs)的可能性,并增加死亡风险。方法:根据CDC的标准,本研究回顾性调查了2018年至2022年巴西圣保罗一所大学医院住院的烧伤患者HAIs的发生率。结果:在此期间,536例患者接受了治疗,88例患者中记录了130例HAIs。患者平均年龄41岁,平均体表面积(TBSA)为20.4%。烧伤的主要原因是易燃液体(39.7%)、电伤(25%)和热液体烫伤(14.8%)。烧伤感染是最常见的HAI(51.5%),其次是血流感染(13.8%)、尿路感染(13.1%)和呼吸机相关性肺炎(10.7%)。在微生物学方面,共分离出141种微生物,其中革兰氏阴性菌占71.6%,革兰氏阳性菌占21.2%,真菌占7.1%。在三个病例中,没有发现微生物。患者死亡率为13.6%。结论:值得注意的是,革兰氏阴性菌在这一人群中占主导地位,导致70%以上的感染,这与其他研究的结果形成对比。研究结果强调了控制感染对降低这一脆弱人群的发病率和死亡率的重要性。
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引用次数: 0
Hernias at the laparoscopic cholecystectomy trocar sites. 腹腔镜胆囊切除术套管针部位疝。
Pub Date : 2025-11-07 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253874-en
Maria DE Lourdes Pessole Biondo-Simões, Rachel Biondo-Simões

Introduction: The surgical approach to the abdomen via laparoscopy has been widely used for cholecystectomy. This access route has demonstrated advantages, including the reduction in the incidence of incisional hernias. Could this really be a reality?

Objective: This survey aims to show the existence of these hernias and the profile of patients who present them.

Method: Incisional hernias operated from January 2017 to May 2024, at the Complexo Hospital do Trabalhador were reviewed. The inclusion criteria were: age 18 years or older and having undergone laparoscopic cholecystectomy, excluding those operated on in the emergency room and those whose medical records did not allow the data to be analyzed to be obtained.

Results: 71 hernias were identified at the trocar site, all in the umbilical position (12.98% of all incisional hernias). It predominated in women (73.24%) and the average age was 53.99 ± 13.33 years. Weight changes were present in 91.05% of patients and obesity in 52.25%. The diagnosis was clinical and the hernias were complex. Furthermore, 38.03% were diabetic and 42.25% had high blood pressure.

Conclusion: Incisional hernia at the umbilical trocar site in laparoscopic cholecystectomy is highly prevalent, with obesity as the main risk factor.

导读:腹腔镜入腹手术已被广泛应用于胆囊切除术。这种通路已证明其优点,包括减少切口疝的发生率。这真的会成为现实吗?目的:本调查旨在显示这些疝的存在和患者的概况。方法:回顾2017年1月至2024年5月在特拉巴尔哈多Complexo医院手术的切口疝。纳入标准为:年龄在18岁或以上,接受过腹腔镜胆囊切除术,不包括在急诊室手术的患者和医疗记录不允许分析数据的患者。结果:套管针部位疝71例,均位于脐部(占切口疝的12.98%)。以女性居多(73.24%),平均年龄53.99±13.33岁。91.05%的患者出现体重变化,52.25%的患者出现肥胖。诊断是临床的,疝是复杂的。38.03%的人患有糖尿病,42.25%的人患有高血压。结论:腹腔镜胆囊切除术脐环针部位切口疝发生率高,肥胖是主要危险因素。
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引用次数: 0
Economic impact of graft's cold ischemia time on infection and post-liver transplant costs. 移植物冷缺血时间对感染和肝移植后费用的经济影响。
Pub Date : 2025-11-07 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253842-en
Deyvid Fernando Mattei DA-Silva, Otávio Monteiro Becker Júnior, Janine Schirmer, Nacime Salomão Mansur, Elizabeth Akemi Nishio, Bartira DE Aguiar Roza

Introduction: Liver transplantation is a complex and costly surgical procedure funded by the Brazilian public health system. This study analyzed the hospital costs of patients who underwent liver transplantation and their relationship with graft cold ischemia time, as well as evaluated the impact of infection rate, length of hospital stay, and hospital expenses on survival and total costs.

Methods: This is a retrospective economic evaluation study that analyzed 40 medical records of patients who underwent liver transplantation in 2018 at a public hospital in São Paulo. Micro- and macro-costing methodologies were applied to calculate direct and fixed postoperative costs.

Results: Each additional hour of cold ischemia time increased the risk of infection by 2.6 times (95% CI: 1.28-7.51; p=0.025). Patients with more than 8 hours of cold ischemia had longer hospital stays (average of 36 days) and higher costs (average of R$98,190.42) compared to those with less than 8 hours (20 days and R$49,519.05). Patients who developed an infection remained hospitalized 2.16 times longer and had higher average total costs (R$148,400.00) compared to those without infection (R$58,200.00). Higher expenditures on materials, medications, nursing care, and prolonged stays in the Intensive Care Unit (ICU) were associated with lower survival.

Conclusion: Cold ischemia time directly influenced the increase in costs and higher rates of posttransplant infection. Higher expenditures on materials, medications, nursing care, and prolonged ICU stays were associated with lower survival rates.

肝移植是一项复杂而昂贵的外科手术,由巴西公共卫生系统资助。本研究分析肝移植患者住院费用及其与移植物冷缺血时间的关系,并评估感染率、住院时间、住院费用对患者生存和总费用的影响。方法:这是一项回顾性经济评估研究,分析了2018年在圣保罗一家公立医院接受肝移植手术的40例患者的病历。微观和宏观成本计算方法应用于计算直接和固定的术后成本。结果:冷缺血时间每延长1 h,感染风险增加2.6倍(95% CI: 1.28 ~ 7.51; p=0.025)。与少于8小时(20天,49,519.05雷亚尔)的患者相比,超过8小时的冷缺血患者住院时间更长(平均36天),费用更高(平均98,190.42雷亚尔)。感染患者的住院时间是未感染患者的2.16倍,平均总费用(148,400.00雷亚尔)高于未感染患者(58,200.00雷亚尔)。较高的材料、药物、护理费用和在重症监护病房(ICU)的住院时间与较低的生存率相关。结论:冷缺血时间直接影响移植费用的增加和移植后感染率的升高。较高的材料、药物、护理费用和延长ICU住院时间与较低的生存率相关。
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引用次数: 0
Nomograms for predicting sentinel lymph node metastasis in melanoma in a Southern Brazilian population: an accuracy study. 预测巴西南部人群黑色素瘤前哨淋巴结转移的nomogram:一项准确性研究。
Pub Date : 2025-11-07 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253873-en
Amarildo Francisco Candiago Júnior, Jefferson Traebert, Eduardo Zanella Cordeiro

Introduction: Sentinel lymph node biopsy is fundamental for staging and prognostication of cutaneous melanoma when indicated. However, it still yields a high rate of negative results. To reduce the rate of true negatives, oncology centers have developed nomograms to better stratify patients for whom the procedure is recommended.

Objective: To study the accuracy of two nomograms developed by the Memorial Sloan-Kettering Cancer Center (MSKCC) and the Melanoma Institute Australia (MIA) for calculating the probability of sentinel lymph node positivity in a population of patients from southern Brazil.

Methods: An accuracy study was conducted, including data from 320 patients diagnosed with melanoma at a referral oncology institution in Santa Catarina, Brazil. The risk of sentinel lymph node positivity was calculated for each patient using the studied nomograms and compared to the results of histopathological examination. Discrimination was assessed by calculating the area under the Receiver Operating Characteristic (ROC) curve, thereby determining the accuracy of each nomogram.

Results: The MSKCC nomogram demonstrated an overall accuracy of 69.05%, while the MIA nomogram showed an accuracy of 68.38%.

Conclusion: The nomograms did not exhibit acceptable levels of accuracy for application in the studied population.

前哨淋巴结活检是皮肤黑色素瘤分期和预后的基础。然而,它仍然产生高比率的负面结果。为了减少真阴性的比率,肿瘤中心已经开发了nomograph,以便更好地对推荐该手术的患者进行分层。目的:研究由纪念斯隆-凯特琳癌症中心(MSKCC)和澳大利亚黑色素瘤研究所(MIA)开发的两种nomogram肿瘤图用于计算巴西南部患者前哨淋巴结阳性概率的准确性。方法:进行了一项准确性研究,包括来自巴西圣卡塔琳娜转诊肿瘤机构诊断为黑色素瘤的320例患者的数据。使用所研究的形态图计算每个患者前哨淋巴结阳性的风险,并与组织病理学检查结果进行比较。通过计算受试者工作特征(ROC)曲线下的面积来评估鉴别性,从而确定每个nomogram的准确性。结果:MSKCC图的总体准确率为69.05%,MIA图的总体准确率为68.38%。结论:在研究人群中,nomogram并没有表现出可接受的准确性。
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Revista do Colegio Brasileiro de Cirurgioes
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