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Antimicrobial effect of biological surgical mesh added with vancomycin or silver nanoparticles for multidrug-resistant bacteria: experimental study in rats. 万古霉素或纳米银纳米颗粒生物手术补片对多重耐药细菌的抗菌作用:大鼠实验研究。
Pub Date : 2026-01-23 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253835-en
Marcelo DE Paula Loureiro, Pietro Maran Novais, Ishmael Thomaz Padilha, Marina Schmid Guérios, Fábio Luigi Crisigiovanni, Victoria Bizzi Vieira, Ana Luiza Masselai, Rodrigo Müller Caravalho, Eduardo Salamacha, Luane Zontta, Marina DA Costa Gomes, Enrico Bertolucci Boscardim, Isadora Utri Andreguetto, Felipe Francisco Tuon

Introduction: Surgical site infection (SSI) and polypropylene mesh (PPM) infections are recurrent problems in abdominal hernia surgeries, highlighting the need for a new antimicrobial material for surgical repair. The aim of this study was to evaluate the in vivo antimicrobial effect of a new biological mesh made of decellularized bovine pericardium (BP), added with vancomycin (VAN) or silver nanoparticles (AgNPs), as prevention for SSI.

Methods: Thirty-five Wistar rats were divided into four groups: BP C+ (n=9) with BP without additions; PP C+ (n=8) with PPM; BP AgNPs (n=9) with BP added with silver nanoparticles; and BP VAN (n=9) with BP added with vancomycin. The 1 cm² meshes were stitched into the muscle fascia under the subcutaneous tissue of the rats' backs, followed by inoculation with methicillin-resistant Staphylococcus aureus. The animals were observed for 7 days, with subsequent euthanasia, and histological and bacteriological analysis.

Results: The BP VAN group had better infection control compared to the PP C+ and BP AgNPs groups (1x10¹ vs. 1.4x10³CFU/g, p=0.0303; 1x10¹ vs. 1.5x104CFU/g, p<0.0001, respectively). BP AgNPs showed less bacterial reduction compared to BP C+ (p=0.042). In the histological analysis, there was a mild inflammatory reaction in BP VAN, moderate in BP C+, and intense in PP C+ and BP AgNPs.

Conclusion: BP added with vancomycin showed promising antimicrobial action, while the use of silver nanoparticles did not demonstrate efficacy in this study.

手术部位感染(SSI)和聚丙烯补片(PPM)感染是腹疝手术中反复出现的问题,突出了对手术修复的新型抗菌材料的需求。本研究的目的是评估由脱细胞牛心包(BP)制成的新型生物网,加入万古霉素(VAN)或银纳米颗粒(AgNPs)预防SSI的体内抗菌效果。方法:35只Wistar大鼠分为4组:BP C+组(n=9), BP不添加;PP C+ (n=8)与PPM;BP AgNPs (n=9)与BP加银纳米颗粒;BP VAN (n=9), BP加万古霉素组。将1 cm²的网片缝合于大鼠背部皮下组织下的肌筋膜中,接种耐甲氧西林金黄色葡萄球菌。观察7天,安乐死,并进行组织学和细菌学分析。结果:与PP C+组和BP AgNPs组相比,BP VAN组的感染控制效果更好(1 × 10¹vs. 1.4 × 10³CFU/g, p=0.0303; 1 × 10¹vs. 1.5 × 104cfu /g, p)。结论:BP加万古霉素具有良好的抗菌作用,而银纳米颗粒在本研究中没有效果。
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引用次数: 0
Between the scalpel and algorithms: how AI is redesigning Surgery. 在手术刀和算法之间:人工智能如何重新设计外科手术。
Pub Date : 2026-01-23 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20250031EDIT01-en
Cristiano Xavier Lima, Marcos André Gonçalves, Arthur DE Oliveira Lima
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引用次数: 0
Technical review by the Brazilian Society of Surgical Oncology and the Brazilian Society of Head and Neck Surgery on hierarchical coding in thyroid surgery. 巴西外科肿瘤学会和巴西头颈外科学会对甲状腺手术分层编码的技术综述。
Pub Date : 2026-01-23 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20250024-en
Carlos Eduardo Santa Ritta Barreira, Fernando Luiz Dias, Terence Pires DE Farias, Luiz Paulo Kowalski, Izabella Costa Santos, José Guilherme Vartanian, André Ferrari Beltrão, Ullyanov Bezerra Toscano DE Mendonça, Bruno Simaan França, Carlos Chone, Antônio Vitor Martins Priante, Guilherme DE Souza Silva, Peterson Fasolo Bilhar, Paola Andrea Galbiatti Pedruzzi, Rafael DE Cicco, Stenio Roberto Santos, Dorival DE Carlucci Junior, Aline DE Oliveira Ribeiro Viana, Christiana Maria Ribeiro Salles Vanni, Marina Azzi Quintanilha, Addilis Fonte Neto, Ricardo Mai Rocha, André Povoa Miranda, Marcelo Cavassani, Ernandes Nakamura, Renato DE Capuzzo, Murilo Catafesta DAS Neves, Pedro Maia Filho, Klecius Leite Fernandes, Mario Augusto DE Castro, Marianne Yumi Nakai, Leandro Luongo Matos Matos, Flavio Carneiro Hojaij, Fábio Capelli, Giulianno Molina DE Melo, Lucio Noleto, Heládio Feitosa E Castro Neto, Fatima Cristina Mendes DE Matos, Alexandre Ferreira Oliveira, Rodrigo Nascimento Pinheiro

The Brazilian Society of Surgical Oncology and the Brazilian Society of Head and Neck Surgery developed a technical consensus on hierarchical coding in thyroid surgery, considering the role of the Brazilian Hierarchical Classification of Medical Procedures in determining appropriate codes. A panel of 40 specialists - recognized academic and clinical leaders from across Brazil - assessed the applicability of procedure codes for common thyroid surgeries and prepared the current consensus. Deliberations were conducted via electronic voting among 37 participants, and consensus was defined as agreement by at least 80%. Scenarios included total thyroidectomy for benign and malignant disease and resection of substernal goiter. The analysis covered codes for laryngeal nerve exploration, neurophysiological monitoring, carotid artery branch ligation, biopsy, parathyroid reimplantation, lymphadenectomy, and neck dissection. Consensus supported the use of the following codes: nerve exploration (83.3%), neurophysiological monitoring (97.3%), biopsy and parathyroid reimplantation (89.2%), cervical lymphadenectomy (89.2%), and unilateral or bilateral neck dissections (97.3% and 94.6%, respectively). No consensus was reached on including carotid artery branch ligation or adding a partial thyroidectomy code for unilateral substernal goiter; therefore, these codes were not validated. The current consensus provides clear, objective guidance on hierarchical coding for thyroid surgery based on technical, scientific, and ethical criteria. It is intended to support attending physicians and auditors by promoting consistency, transparency, and reduced conflict in clinical and administrative settings.

考虑到《巴西医疗程序分级分类》在确定适当编码方面的作用,巴西肿瘤外科学会和巴西头颈外科学会就甲状腺手术的分级编码达成了技术共识。一个由40名专家组成的小组——来自巴西各地公认的学术和临床领导者——评估了普通甲状腺手术程序代码的适用性,并制定了目前的共识。37名参与者通过电子投票进行了审议,共识被定义为至少80%的同意。方案包括甲状腺全切除术的良性和恶性疾病和切除胸骨下甲状腺肿。分析的代码包括喉神经探查、神经生理监测、颈动脉分支结扎、活检、甲状旁腺再植、淋巴结切除术和颈部清扫。共识支持使用以下代码:神经探查(83.3%),神经生理监测(97.3%),活检和甲状旁腺再植(89.2%),颈部淋巴结切除术(89.2%),单侧或双侧颈部清扫(分别为97.3%和94.6%)。对于包括颈动脉分支结扎或增加单侧胸骨下甲状腺肿的部分甲状腺切除术代码没有达成共识;因此,这些代码没有被验证。目前的共识为基于技术、科学和伦理标准的甲状腺手术分级编码提供了清晰、客观的指导。它旨在通过促进临床和行政环境中的一致性、透明度和减少冲突来支持主治医生和审核员。
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引用次数: 0
Indoor Location Technology for Managing Elective Surgery Patients in Hospitals. 医院择期手术患者管理的室内定位技术。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253813-en
Ibtisam Hamzeh Mohammad Husein Shalabi, Laura Maria César Schiesari

Introduction: With the increase in healthcare spending, efficient resource management in surgical hospitals has become essential, especially with regard to managing patient flow to avoid delays. Therefore, tools that can provide instant visibility of the patients location in each sector can be of great value in choices about resource allocation. Therefore, the objective of this study was to evaluate the applicability of indoor location technology in a hospital environment.

Methods: Prospective study, carried out from February to March 2024, in a private surgical hospital, with tertiary structure, specialized in the care of elderly patients. The records of the path of each elective patient were mapped from their arrival to the moment of their discharge, as well as the activities of the professionals involved, through an indoor Bluetooth location device.

Results: 320 patients were analyzed, with an average stay time in the reception of 25 minutes and the time in the preoperative preparation unit of 107 minutes. Urology, mastology, and oncology surgeries represented 50% of the case series. The median transport time for these patients was 19 minutes. Reception (75.6%) and nursing admission (72.5%) were the sectors with the highest percentage of correct execution. The delay rate was 89.9% in the first time slot, and in subsequent times the delay was significantly lower (70.1%) compared to the time scheduled on the map.

Conclusion: Indoor location technology has applicability when used in the intra-hospital environment in the management of surgical patients, facilitating the identification of bottlenecks and their causes.

导言:随着医疗保健支出的增加,外科医院有效的资源管理变得至关重要,特别是在管理患者流量以避免延误方面。因此,能够提供每个部门患者位置的即时可见性的工具在选择资源分配时具有很大的价值。因此,本研究的目的是评估室内定位技术在医院环境中的适用性。方法:前瞻性研究,于2024年2月- 3月在一家三级结构的专科老年外科医院进行。通过室内蓝牙定位设备,绘制了每位选择性患者从到达到出院的路径记录,以及相关专业人员的活动。结果:分析320例患者,平均在接待处停留时间为25分钟,在术前准备单元停留时间为107分钟。泌尿外科、乳腺外科和肿瘤外科占病例总数的50%。这些患者的中位转运时间为19分钟。接待处(75.6%)和护理住院(72.5%)是正确执行率最高的部门。在第一个时隙的延迟率为89.9%,在随后的时间延迟率明显低于地图上计划的时间(70.1%)。结论:室内定位技术在医院内环境下对外科患者的管理具有适用性,便于发现瓶颈及其原因。
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引用次数: 0
Quality of life assessment in patients undergoing partial and total thyroidectomy. 甲状腺部分和全切除术患者的生活质量评估。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253870-en
Pedro Henrique Serra Carvalho Dos Santos, Roberta Zambo Galafassi, Giulia Fernandes Manhães Rodrigues Lopes, Leiziane Assunção Alves Guimarães, Fatima Rosalia Hartelsberger Bobadilla, Inês Nobuko Nishimoto, Rogério Aparecido Dedivitis

Introduction: Thyroidectomy, which consists of partial or total removal of the thyroid gland, is a commonly performed surgery to treat various thyroid diseases. In recent years, the trend has been toward partial thyroidectomies, due to their association with lower complication rates and the fact that they may be sufficient for adequate management.

Objective: To evaluate the impact of partial and total thyroidectomy on quality of life.

Methods: This study used the ThyPro questionnaire, which assesses the quality of life of patients with thyroid disorders, to investigate the impact of different thyroidectomy approaches on patients' quality of life.

Results: The postoperative complications were transient unilateral recurrent nerve paralysis (6.5%) and transitory hypoparathyroidism (22.4%). The quality of life outcomes after thyroidectomy were favorable. The extension of the thyroidectomy did not present statistical difference (p = 0.982). Significantly lower scores were associated with female gender and neck dissection.

Conclusion: Quality of life scores were high, with lower scores among women and neck dissection.

简介:甲状腺切除术包括部分或全部切除甲状腺,是治疗各种甲状腺疾病的常用手术。近年来,由于甲状腺部分切除术的并发症发生率较低,而且可能足以进行适当的治疗,因此趋势是甲状腺部分切除术。目的:探讨甲状腺部分切除术和甲状腺全切除术对患者生活质量的影响。方法:本研究采用甲状腺功能障碍患者生活质量评估问卷ThyPro,探讨不同甲状腺切除术方式对患者生活质量的影响。结果:术后并发症为一过性单侧复发性神经麻痹(6.5%)和一过性甲状旁腺功能低下(22.4%)。甲状腺切除术后的生活质量良好。甲状腺切除的范围差异无统计学意义(p = 0.982)。较低的评分与女性和颈部解剖有关。结论:患者的生活质量评分较高,女性患者和颈部夹层患者的生活质量评分较低。
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引用次数: 0
Robotic surgery in the interior of Brazil: Is it possible? 机器人手术在巴西内陆:可能吗?
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253838-en
Jorge Roberto Mercante-Carlotto, Petra Mistura Arcoverde Cavalcanti, Ana Luísa Dos Santos Carregosa, Eduarda Leitzke, Lara Fabian DE Moura, Milena DE Almeida DA Motta, Nicole Mombelli Mattei, Rodrigo Guerra-Casarin, Tami Zang Crestani

Introduction: Robotic surgery has been used in the treatment of various surgical diseases due to its precision and satisfactory outcomes. This study aims to describe the profile of patients undergoing robotic surgery at the Hospital de Clínicas de Passo Fundo and analyze the variables related to the procedure and its outcomes.

Methods: A total of 215 medical records of patients who underwent robotic surgery at the Regional Robotic Surgery Center of the Hospital de Clínicas de Passo Fundo were reviewed, from the start of the program in 2023 until March 2024. Sex, age, comorbidities, and perioperative and postoperative data were evaluated.

Results: The sample had a predominance of males (73.5%). The average age was 61 years. Systemic arterial hypertension was the most prevalent comorbidity (43.7%). Regarding operative time, the first six months had a higher median total time (300 minutes) compared to the last six months (245 minutes) with p≤0.001.

Conclusion: The implementation of a robotic surgery center in the interior of Brazil proved to be feasible, with favorable outcomes, progressive reductions in surgical times, and regional benefits by expanding access to cutting-edge technologies.

机器人手术以其精确性和令人满意的效果被广泛应用于各种外科疾病的治疗中。本研究旨在描述在医院de Clínicas de Passo Fundo接受机器人手术的患者的概况,并分析与手术及其结果相关的变量。方法:回顾了从2023年项目开始到2024年3月期间,在Clínicas de Passo Fundo医院区域机器人手术中心接受机器人手术的患者的215份医疗记录。评估性别、年龄、合并症、围手术期和术后数据。结果:样本以男性为主(73.5%)。平均年龄为61岁。全身性动脉高血压是最常见的合并症(43.7%)。关于手术时间,前6个月的中位总时间(300分钟)高于后6个月(245分钟),p≤0.001。结论:在巴西内陆地区实施机器人手术中心被证明是可行的,效果良好,手术时间逐步减少,并通过扩大尖端技术的获取而获得区域效益。
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引用次数: 0
Can viable bacteria be present in the surface of ready-to-use surgical instruments? 手术器械表面是否存在活菌?
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20253852-en
Carlos Roberto DE Oliveira Sauer, Francisco Hideo Aoki, Rogério Hakio Kuboyama, Márcia Regina Suzuki DE Lima, Inês Helena DE Barros Leal Saraiva, Cely Barreto Silva, Francisco Américo Fernandes Neto, Mauro José DA Costa Salles

Introduction: biofilm is considered a challenge regarding treatment of chronic diseases and, after a detailed observation of cleaning and sterilization processes, it is considered could be a threat to sterility of surgical instruments that are "ready to use". Colored plastic bands (color coding tapes for marking surgical instruments) are frequently used to assist in the assembly of surgical instrument boxes. These bands form a lifting, which makes cleaning the material difficult. Epidemiological data regarding the frequency of surgical site infection in Brazil (up to 24% in Center-West Region) may be suggestive of contamination of operative instruments. The objective of this study is to answer the question: is there a risk of biofilm on ready-to-use surgical instruments?

Methods: narrative literature review.

Results: 296 articles were found and a total of 163 were selected for detailed reading, of which 78 were included. During the survey, four knowledge domains were outlined: microbiology, pathophysiology/epidemiology, technology and management. This review pointed out the risk of the bacterial load prior to autoclaving, the efficiency of the sterilization method regarding the presence of microscopic soils and, under current conditions, the ability of the Material and Sterilization Centers to ensure adequate cleaning.

Conclusion: after working extensively to associate all the collected information, there is a considerable probability of bacterial biofilms in ready-to-use surgical instruments and, therefore further research in this field of microbiology is justified, with an emphasis on improving process quality indicators, giving the potential impact on reduction of surgical site infection rates.

导言:生物膜被认为是慢性病治疗方面的一个挑战,在对清洁和灭菌过程进行详细观察后,认为它可能对“准备使用”的手术器械的无菌性构成威胁。彩色塑料带(标记手术器械的彩色编码带)经常用于辅助手术器械盒的组装。这些带形成一个提升,这使得清洗材料困难。关于巴西手术部位感染频率的流行病学数据(在中西部地区高达24%)可能提示手术器械污染。本研究的目的是回答这样一个问题:即用型手术器械是否存在生物膜的风险?方法:叙述文献法。结果:共检索到296篇文章,筛选出163篇进行详细阅读,其中78篇被纳入。在调查中,概述了四个知识领域:微生物学,病理生理学/流行病学,技术和管理。这篇综述指出了高压灭菌前细菌负荷的风险,灭菌方法在存在微观土壤时的效率,以及在当前条件下,材料和灭菌中心确保充分清洁的能力。结论:在对收集到的所有信息进行广泛关联后,现成手术器械中存在细菌生物膜的可能性相当大,因此在微生物学领域的进一步研究是合理的,重点是提高工艺质量指标,对降低手术部位感染率有潜在的影响。
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引用次数: 0
A paradigm shift in Diastasis Recti surgery: The Bikini-line robotic approach. 直肠移位手术的范式转变:比基尼线机器人方法。
Pub Date : 2026-01-12 eCollection Date: 2026-01-01 DOI: 10.1590/0100-6991e-20243846-en
Andre Luiz Gioia Morrell, Allan Gioia Morrell, Alexander Charles Morrell Junior, Alexander Charles Morrell

Introduction: diastasis recti surgery has been known worldwide for open surgical techniques involving significant tissue manipulation, skin flap and larger incisions. Traditional methods typically required extended recovery times and posed higher risks of complications and scarring issues. The advent of robotic-assisted surgery has revolutionized the treatment paradigm for abdominal wall defects and its remarkable outcomes encouraged expanding its applications towards diastasis recti pathologies. Better visualization and more ergonomic instruments foster a minimal scarring procedure, allowing surgeons to improve aesthetic and recovery outcomes following diastasis recti correction in a posterior approach. This article describes a robotic surgical technique and results to an unprecedented approach, putting its form of treatment into another perspective.

Technical report: a step-by-step guided technique of this novel technique is described using detailed port placement and figures to assure optimal aesthetic and functional outcomes whenever acting in minimally invasive diastasis recti repair with the da Vinci platform.

Conclusion: The described technique reveals a hidden minimal incisions procedure avoiding skin flaps, scarring issues, and minimizing wound morbidity. Through a step-by-step guide, this report establishes an unprecedent technique description transforming the diastasis recti surgery scenario and its aesthetic outcomes with a safe minimally invasive surgery.

简介:直肠转移手术以开放性手术技术闻名于世,涉及重要的组织操作、皮瓣和更大的切口。传统的方法通常需要较长的恢复时间,并带来更高的并发症和疤痕问题的风险。机器人辅助手术的出现彻底改变了腹壁缺陷的治疗模式,其显著的效果鼓励扩大其在转移性直肠病变中的应用。更好的视觉效果和更符合人体工程学的器械可使手术瘢痕最小化,使外科医生能够在后路手术中改善椎体分离矫正后的美观和恢复效果。本文描述了一种前所未有的机器人手术技术和结果,将其治疗形式置于另一个角度。技术报告:这项新技术的一步一步的指导技术被描述为使用详细的端口放置和数字,以确保最佳的美学和功能结果,无论何时使用达芬奇平台进行微创移位直肠修复。结论:所描述的技术揭示了一种隐藏的最小切口手术,避免了皮瓣,瘢痕问题,并将伤口发病率降到最低。通过一步一步的指导,本报告建立了一个前所未有的技术描述,用安全的微创手术改变了直肠移位手术的场景和美学结果。
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引用次数: 0
Factors associated with fasting time in pediatric patients hospitalized for surgery. 儿科手术住院患者禁食时间的相关因素
Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253889-en
Laura Naspitz, Fernanda Luísa Ceragioli Oliveira, Renato Lopes DE Souza, Tulio Konstantyner

Introduction: Shorter fasting periods before and after surgery have been associated with better postoperative recovery and lower morbidity and mortality. However, it is not always possible to achieve current recommendations in pediatric practice. Therefore, it is essential to study fasting time and its associated factors to implement better care strategies.

Methods: Cohort of 284 pediatric patients admitted for surgery between 2020-2021, Hospital São Paulo, Brazil. Data was collected through interviews and medical records. Simple and multiple linear models and logistic regression models were adjusted to study the associations.

Results: All preoperative patients fasted for a prolonged period and most resumed feeding 6 hours after the end of anesthesia. Preoperative fasting time was shorter for elective surgery than for urgent surgery (p=0.025). Factors associated with a longer preoperative fasting time (minutes) were: older age in years (ß=10; 95% CI=5.2-14.8) and history of previous surgery (ß=76.6; 95% CI=28.0-125.1). Factors associated with postoperative fasting time longer than 6 hours were: no immediate postoperative care in the surgical ward (OR=6.05; 95%CI=2.25-16.22), presence of complications during surgery (OR=3. 53; 95%CI=1.19-10.47), major operation size (OR=3.85; 95%CI=1.49-9.93), abdominal surgery (OR=36.52; 95%CI=13.48-98.91) and vomiting in the first 24 hours (OR=3.44; 95%CI=1.54-7.69).

Conclusion: There are potentially modifiable factors associated with longer fasting times. Education and organization of the healthcare team regarding patient characteristics, care dynamics, and clinical complications may contribute to greater optimization of fasting times in pediatric surgical patients.

前言:手术前后较短的禁食时间与更好的术后恢复和较低的发病率和死亡率相关。然而,在儿科实践中并不总是能够达到目前的建议。因此,研究禁食时间及其相关因素对实施更好的护理策略至关重要。方法:对巴西圣保罗医院2020-2021年间住院的284例儿科患者进行队列研究。通过访谈和医疗记录收集数据。调整简单和多元线性模型以及逻辑回归模型来研究相关性。结果:术前患者禁食时间均较长,麻醉结束后6小时恢复进食。择期手术术前禁食时间短于急诊手术(p=0.025)。术前禁食时间(分钟)较长的相关因素是:年龄较大(10岁;95% CI=5.2-14.8)和既往手术史(ß=76.6; 95% CI=28.0-125.1)。术后禁食时间超过6小时的相关因素有:外科病房未立即接受术后护理(OR=6.05; 95%CI=2.25-16.22)、手术中出现并发症(OR=3)。53个;95%CI=1.19 ~ 10.47)、大手术规模(OR=3.85; 95%CI=1.49 ~ 9.93)、腹部手术(OR=36.52; 95%CI=13.48 ~ 98.91)和前24小时呕吐(OR=3.44; 95%CI=1.54 ~ 7.69)。结论:有可能改变的因素与较长的禁食时间有关。对医疗团队进行有关患者特征、护理动态和临床并发症的教育和组织,可能有助于更好地优化儿科外科患者的禁食时间。
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引用次数: 0
Healthcare-Associated Infections in a Burn Treatment Unit. 烧伤治疗室医疗保健相关感染
Pub Date : 2025-12-15 eCollection Date: 2025-01-01 DOI: 10.1590/0100-6991e-20253882-en
Marcelo Mourão, Marília Baeninger, Thaysa Sobral Antonelli, Daniela Vieira DA Silva Escudero, Maria Claudia Stockler DE Almeida, Alfredo Gragnani

Introduction: Severe burns significantly weaken the immune system and disrupt the skin's natural barrier, which increases the likelihood of healthcare-associated infections (HAIs) and raises the risk of mortality.

Methods: Based on CDC criteria, this study retrospectively examines the incidence of HAIs in burn patients hospitalized at a university hospital in São Paulo, Brazil, over five years from 2018 to 2022.

Results: 536 patients were treated during this time, with 130 HAIs recorded in 88 individuals. The average age of the patients was 41 years, and the mean total body surface area (TBSA) affected by burns was 20.4%. The primary causes of burns were flammable liquids (39.7%), electrical injuries (25%), and scalds from heated liquids (14.8%). Burn wound infections were the most frequent HAI (51.5%), followed by bloodstream infections (13.8%), urinary tract infections (13.1%), and ventilator-associated pneumonia (10.7%). Regarding microbiological findings, 141 microorganisms were isolated, with gram-negative bacteria making up 71.6% of the total, gram-positive bacteria accounting for 21.2%, and fungi representing 7.1%. In three cases, no microorganism was identified. The mortality rate among these patients was 13,6%.

Conclusion: Notably, the predominance of gram-negative bacteria in this population, responsible for more than 70% of infections, contrasts with findings from other studies. The findings highlight the importance of infection control to reduce morbidity and mortality in this vulnerable population.

严重烧伤会显著削弱免疫系统,破坏皮肤的天然屏障,从而增加医疗保健相关感染(HAIs)的可能性,并增加死亡风险。方法:根据CDC的标准,本研究回顾性调查了2018年至2022年巴西圣保罗一所大学医院住院的烧伤患者HAIs的发生率。结果:在此期间,536例患者接受了治疗,88例患者中记录了130例HAIs。患者平均年龄41岁,平均体表面积(TBSA)为20.4%。烧伤的主要原因是易燃液体(39.7%)、电伤(25%)和热液体烫伤(14.8%)。烧伤感染是最常见的HAI(51.5%),其次是血流感染(13.8%)、尿路感染(13.1%)和呼吸机相关性肺炎(10.7%)。在微生物学方面,共分离出141种微生物,其中革兰氏阴性菌占71.6%,革兰氏阳性菌占21.2%,真菌占7.1%。在三个病例中,没有发现微生物。患者死亡率为13.6%。结论:值得注意的是,革兰氏阴性菌在这一人群中占主导地位,导致70%以上的感染,这与其他研究的结果形成对比。研究结果强调了控制感染对降低这一脆弱人群的发病率和死亡率的重要性。
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Revista do Colegio Brasileiro de Cirurgioes
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