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Myelomeningocele: need for long-time complex follow-up-an observational study. 脊髓脊膜膨出:需要长期复杂的随访——一项观察性研究。
Q1 Medicine Pub Date : 2019-03-08 eCollection Date: 2019-01-01 DOI: 10.1186/s13013-019-0177-3
Thomas Bakketun, Nils Erik Gilhus, Tiina Rekand

Background: Myelomeningocele (MMC) is a congenital disorder that causes a variety of acute as well as late complications. Numerous health problems in adulthood have been described by the persons with MMC but not studied in clinical setting. This study gives implications for organization of the follow-up in adulthood.

Objectives: To investigate the need for follow-up from different medical specialists as well as the need for organized focused rehabilitation among adults with MMC.

Methods: Retrospective cohort study on adults with MMC including multiple departments in a university hospital in Norway. The number and cause of specialized hospital consultations were recorded for every patient. Correlation between childhood health condition related to MMC and the need for specialized consultations in adulthood as well as correlations between number of consultations and anatomical level of MMC, age, and observation time was performed for the whole group.

Results: In total, 38 patients had 672 consultations related to MMC. The most frequent departments were neurology, neurosurgery, urology, gastroenterology, and orthopedics. Most consultations were planned. Complexity of MMC-related health condition correlated to number of specialist consultations (rho = 0.420, p = 0.009). Anatomical level of MMC, age, and length of observation time did not correlate with consultations. Pain and shunt failure were the most common reasons for consultations.

Conclusions: Persons with MMC have a need for continuous, life-long multispecialized follow-up and rehabilitation. This is crucial for optimal function, satisfaction with life, and for long-term survival. Systematic follow-up together with rehabilitation will optimize health service.

背景:脊髓脊膜膨出(MMC)是一种先天性疾病,可引起各种急性和晚期并发症。患有MMC的人描述了许多成年期的健康问题,但尚未在临床环境中进行研究。本研究为成年期随访的组织提供了启示。目的:调查成人MMC患者对不同医学专家随访的需求以及有组织的重点康复的需求。方法:对挪威某大学医院多科室成人MMC患者进行回顾性队列研究。记录了每位患者到专科医院就诊的次数和原因。对整个组进行儿童期MMC相关健康状况与成年期MMC专科会诊需求的相关性,以及会诊次数与MMC解剖水平、年龄、观察时间的相关性。结果:38例患者共进行了672次与MMC相关的咨询。最常见的科室是神经内科、神经外科、泌尿外科、消化内科和骨科。大多数磋商都已计划好。mmc相关健康状况的复杂性与专家咨询次数相关(rho = 0.420, p = 0.009)。MMC的解剖水平、年龄和观察时间的长短与会诊无关。疼痛和分流失败是最常见的咨询原因。结论:MMC患者需要持续的、终身的多专业随访和康复。这对最佳功能、生活满意度和长期生存至关重要。系统的随访和康复将优化卫生服务。
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引用次数: 5
Morphometric characteristics of the thoracοlumbar and lumbar vertebrae in the Greek population: a computed tomography-based study on 900 vertebrae-"Hellenic Spine Society (HSS) 2017 Award Winner". 希腊人胸椎和腰椎的形态特征:基于900个椎骨的计算机断层扫描研究——“希腊脊柱学会(HSS) 2017年获奖者”。
Q1 Medicine Pub Date : 2019-02-19 eCollection Date: 2019-01-01 DOI: 10.1186/s13013-019-0176-4
Theodoros B Grivas, Olga Savvidou, Stefanos Binos, Georgios Vynichakis, Dimitrios Lykouris, Michail Skaliotis, Eleni Velissariou, Konstandinos Giotopoulos, Konstandinos Velissarios

Background: Vertebrae morphology appears to have genetic and ethnic variations. Knowledge of the vertebra and pedicle morphology is essential for proper selection and safe application of transpedicular screws. The aim of this study is to create a morphometric database for thoracolumbar and lumbar vertebrae (T9-L5) among individuals of both sexes in the Greek population.

Material and methods: The morphometric dimensions of T9-L5 vertebrae on computed tomography (CT) scan images were measured in 100 adults (79 males and 21 females), without spinal pathology, age from 33 to 87 years old (mean 70 ± 8.73 years). The anterior vertebral body height (AVBH), the posterior vertebral body height (PVBH), the angle formed by the upper end plate of vertebral body and the horizontal line in the sagittal plane, the inner cancellous and outer cortical pedicle height and width, the angle formed by the longitudinal trajectory of the right- and left-sided pedicles and the midline anteroposterior axis of the vertebra (pedicle axis angle (PAA)), and the postero-anterior trajectory's length of the pedicle from the entry point to the anterior cortex of the vertebra (PTLP), for the right- and left-sided pedicles, were calculated. The Mann-Whitney U tests were conducted to compare the differences in various morphometric characteristics between sexes. The collected data were statistically analyzed using the SAS/STAT software 3.1.3 and SPSS version 22. The statistical significance was set at the level of p < 0.05. The intra- and inter-observer reliability of the measured parameters was also calculated.

Results: The L5 vertebra had the maximum AVBH with a mean of 28.47 mm (SD ± 2.55 mm) in males and 26.48 mm (SD ± 1.61 mm) in females. The maximum PVBH in males was at L1 vertebra with a mean of 27.77 mm (SD ± 1.64 mm) and in females at L2 vertebral with a mean of 27.11 mm (SD ± 1.27 mm). Regarding the left pedicle dimensions, the maximum inner cancellous and outer cortical pedicle height was at T11 with a mean of 12.86 mm (SD ± 1.26 mm) and 18.82 mm (SD ± 1.37 mm) in males and 10.24 mm (SD ± 1.88 mm) and 16.19 mm (SD ± 3.27 mm) in females, respectively. The maximum inner cancellous and outer cortical pedicle width was at L5 with a mean of 11.57 mm (SD ± 1.97 mm) and 17.08 mm (SD ± 1.97 mm) in males and 10.24 mm (SD ± 1.88 mm) and 16.27 mm (SD ± 3.27 mm) in females, respectively. The largest PAA was found at the L5 with a mean angle of 26.23° (SD ± 2.65°) in males and 23.63° (SD ± 4.59°) in females, respectively. The maximum PTLP was found at the level of L4 with a mean of 55.31 mm (SD ± 4.52 mm) in males and 48.7 mm (SD ± 4.17 mm) in females, respectively. Regarding the right pedicle dimensions, the maximum inner cancellous and outer cortical pedicle height was found at T12 with a mean of 13.03 mm (SD ± 2.01 mm) and 18.01 mm (SD ± 1.56

背景:椎骨形态似乎具有遗传和种族差异。椎体和椎弓根形态学知识对于正确选择和安全应用椎弓根螺钉至关重要。本研究的目的是建立希腊人群中男女个体胸腰段和腰椎(T9-L5)的形态测量数据库。材料与方法:对100例无脊柱病理的成人(男79例,女21例),年龄33 ~ 87岁(平均70±8.73岁),T9-L5椎体的CT扫描图像进行形态测量。前椎体高度(AVBH)、后椎体高度(PVBH)、椎体上端板与矢状面水平线形成的夹角、内松质和外皮质椎弓根高度和宽度、左右椎弓根纵向轨迹与椎弓根前后中线形成的夹角(椎弓根轴线角(PAA))、计算右侧和左侧椎弓根从入口点到椎体前皮质(PTLP)的后-前轨迹长度。进行了Mann-Whitney U测试,以比较两性之间各种形态特征的差异。采用SAS/STAT 3.1.3软件和SPSS 22软件对收集的数据进行统计学分析。结果:L5椎体AVBH最大,男性平均28.47 mm (SD±2.55 mm),女性平均26.48 mm (SD±1.61 mm)。男性最大PVBH位于L1椎体,平均27.77 mm (SD±1.64 mm),女性位于L2椎体,平均27.11 mm (SD±1.27 mm)。左侧椎弓根尺寸,内松质和外皮质椎弓根最大高度为T11,雄性平均为12.86 mm (SD±1.26 mm)和18.82 mm (SD±1.37 mm),雌性分别为10.24 mm (SD±1.88 mm)和16.19 mm (SD±3.27 mm)。内松质根和外皮质根最大宽度为L5,雄性平均为11.57 mm (SD±1.97 mm)和17.08 mm (SD±1.97 mm),雌性分别为10.24 mm (SD±1.88 mm)和16.27 mm (SD±3.27 mm)。PAA在L5处最大,雄性和雌性的平均角度分别为26.23°(SD±2.65°)和23.63°(SD±4.59°)。PTLP在L4水平最大,雄性平均55.31 mm (SD±4.52 mm),雌性平均48.7 mm (SD±4.17 mm)。在右侧椎弓根尺寸方面,雄鼠椎弓根内侧松质部和外侧皮质部高度在T12时最大,平均分别为13.03 mm (SD±2.01 mm)和18.01 mm (SD±1.56 mm),雌鼠椎弓根内侧松质部和外侧皮质部高度分别为10.24 mm (SD±1.23 mm)和16.14 mm (SD±1.23 mm)。内松质和外皮质蒂最大宽度为L5,雄性平均11.3 mm (SD±2.86 mm)和16.34 mm (SD±2.98 mm),雌性分别为12 mm (SD±3.18 mm)和15.69 mm (SD±2.59 mm)。较大的PAA在L5椎体,男性平均为25.7°(SD±5.19°),女性为25.56°(SD±5.31°)。最大PTLP在L3水平,雄性平均为54.86 mm (SD±3.18 mm),雌性平均为49.01 mm (SD±2.97 mm)。结论:本研究提供了希腊人群从T9到L5胸腰椎和腰椎形态计量学特征的数据库。这一数据库可能对今后的比较研究具有重要意义。它还可以作为检测脊柱病理变化的基础,进而制定手术干预计划。研究发现,希腊人的胸腰椎和腰椎的尺寸是性别依赖的。在目前的研究中,与其他西方人群相比,椎骨和椎弓根的尺寸似乎有一些相似之处。然而,在胸腰椎区,由于内松质椎弓根宽度狭窄,T9和T10的椎弓根很难容纳4.00 mm的椎弓根螺钉。重要的是,本研究测量的椎体和椎弓根尺寸可用于指导希腊人群椎弓根螺钉的选择,并指导进一步的研究。
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引用次数: 9
Principal component analysis of the relationship between pelvic inclination and lumbar lordosis. 骨盆倾斜与腰椎前凸关系的主成分分析。
Q1 Medicine Pub Date : 2019-02-13 eCollection Date: 2019-01-01 DOI: 10.1186/s13013-019-0175-5
Geoff Dakin, Raymond J Turner, Stephana J Cherak

Background: The purpose of this study was to describe the relationship between pelvic inclination (PI) and lumbar lordosis (LL). Pelvic inclination and pelvic tilt are two different names for the same metric. The geometrical parameters of the spine and pelvis were measured using surface topography scanning, and the data was explored for any physical relationships using principal component analysis.Once widely assumed to be a direct correlation, research in the 1980s first cast doubt upon the PI to LL relationship. And yet, other studies have suggested a relationship does exist. Decades later, the rehabilitation professionals often still rely on this supposed correlation when making decisions about rehabilitation treatment interventions. This theoretical relationship requires further clarification, which is explored herein.

Methods: Surface topography imaging is a technology that has proven to be a radiation-free way to produce accurate, reliable skeletal alignment measures. Patient data from one physical rehabilitation clinic was collected at the time of initial assessment. Patients presented with a wide range of musculoskeletal complaints. Surface topography scans were performed on 107 patients at the commencement and completion of their therapy. Principal component analysis was performed on the collected data to determine how these spine and pelvic alignment parameters changed between the two points in time and what trends and/or relationships exist between the parameters. Our analysis evaluated eight spinal and pelvic measurements as input and focused on LL and PI as the two principal components at time points of beginning and completion of treatment.

Results: Pelvic inclination and lumbar lordosis changed during treatment but were not correlated.

Conclusion: Our data demonstrates that pelvic inclination and lumbar lordosis do not have a predictable relationship as previously assumed.

背景:本研究的目的是描述骨盆倾斜(PI)和腰椎前凸(LL)之间的关系。骨盆倾斜和骨盆倾斜是同一度量的两个不同名称。使用表面形貌扫描测量脊柱和骨盆的几何参数,并使用主成分分析探索数据的任何物理关系。曾经被广泛认为是直接相关的,20世纪80年代的研究首次对PI与LL的关系提出了质疑。然而,其他研究表明这种关系确实存在。几十年后,在决定康复治疗干预措施时,康复专业人员往往仍然依赖于这种假定的相关性。这种理论关系需要进一步澄清,本文将对此进行探讨。方法:表面形貌成像是一种技术,已被证明是一种无辐射的方式,产生准确,可靠的骨骼对准措施。在初步评估时收集了一家物理康复诊所的患者数据。患者表现出广泛的肌肉骨骼疾病。在治疗开始和结束时对107例患者进行表面形貌扫描。对收集的数据进行主成分分析,以确定这些脊柱和骨盆对齐参数在两个时间点之间如何变化,以及参数之间存在什么趋势和/或关系。我们的分析评估了8个脊柱和骨盆测量作为输入,并重点关注LL和PI作为治疗开始和完成时间点的两个主要组成部分。结果:盆腔倾斜和腰椎前凸在治疗期间有所改变,但不相关。结论:我们的数据表明,骨盆倾斜和腰椎前凸并不像以前假设的那样具有可预测的关系。
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引用次数: 2
Sagittal spinopelvic malalignment in degenerative scoliosis patients: isolated correction of symptomatic levels and clinical decision-making. 退行性脊柱侧凸患者矢状面脊柱骨盆错位:症状水平的孤立矫正和临床决策。
Q1 Medicine Pub Date : 2018-12-27 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0174-y
Steven M Presciutti, Philip K Louie, Jannat M Khan, Bryce A Basques, Comron Saifi, Christopher J Dewald, Dino Samartzis, Howard S An

Background: This study aims to determine if (1) loss of lumbar lordosis (LL), often associated with degenerative scoliosis (DS), is structural or rather largely due to positional factors secondary to spinal stenosis; (2) only addressing the symptomatic levels with a decompression and posterolateral fusion in carefully selected patients will result in improvement of sagittal malalignment; and (3) degree of sagittal plane correction achieved with such a local fusion could be predicted by routine pre-operative imaging.

Methods: A retrospective study design with prospectively collected imaging data of a consecutive series of surgically treated DS patients who underwent decompression and instrumented fusion at only symptomatic levels was performed. Pre- and post-operative plain radiographs and pre-operative magnetic resonance imaging (MRIs) of the spinopelvic region were analyzed. LL, pelvic incidence (PI), pelvic tilt (PT), and sacral slope (SS) were assessed in all patients. As a requirement for the surgical strategy, all patients presented with a pre-operative PI-LL mismatch greater than 10°. Post-operative complications were assessed.

Results: Pre-operative MRIs and lumbar extension radiographs revealed a mean LL of 42° (range 10-66°) and 48° (range 20-74°), respectively, in 68 patients (mean follow-up 29 months). LL post-operatively was corrected to a mean PI-LL of 10°. Of patients who achieved PI-LL mismatch within 10o on their pre-operative extension lateral lumbar radiographs, 62.5% were able to maintain a PI-LL mismatch within 10° on their initial post-operative films. Only 37.5% were not able to achieve that mismatch on extension radiographs (p = 0.001, OR = 9.58). Similarly, 54.2% were able to achieve a PI-LL < 10° on initial post-operative radiographs, when pre-operative MRI revealed a PI-LL mismatch within 10°. In contrast, only 20.5% achieved that goal post-operatively if their mismatch was greater than 10o on their MRI (p = 0.003, OR = 4.25).

Conclusion: With a decompression and instrumented fusion of only the symptomatic levels in symptomatic DS patients, we were able to achieve a PI-LL mismatch to within 10°. The loss of LL observed pre-operatively may be largely positional rather than structural. The amount of LL correction observed immediately after surgery can be predicted from pre-operative lumbar extension radiographs and supine sagittal MRI.

背景:本研究旨在确定(1)腰椎前凸(LL)的丧失,通常与退行性脊柱侧凸(DS)相关,是结构性的还是很大程度上是由于椎管狭窄继发的体位因素所致;(2)只有在精心挑选的患者中通过减压和后外侧融合来解决症状水平,才能改善矢状面不对中;(3)这种局部融合所达到的矢状面矫正程度可以通过常规术前影像学预测。方法:回顾性研究设计,前瞻性收集连续系列手术治疗的退行性椎体滑移患者的影像学资料,这些患者仅在症状水平上进行减压和内固定融合。分析术前、术后椎盂区x线平片及术前磁共振成像(mri)。评估所有患者的LL、骨盆发生率(PI)、骨盆倾斜(PT)和骶骨坡度(SS)。作为手术策略的要求,所有患者术前PI-LL失配均大于10°。评估术后并发症。结果:68例患者(平均随访29个月)的术前mri和腰椎伸展片显示平均LL分别为42°(范围10-66°)和48°(范围20-74°)。术后将PI-LL矫正为平均10°。在术前扩展侧位腰椎x线片上PI-LL失配在100°范围内的患者中,62.5%的患者在最初的术后x线片上能够将PI-LL失配维持在10°范围内。只有37.5%的患者在扩展x线片上不能达到这种不匹配(p = 0.001, OR = 9.58)。同样,当术前MRI显示PI-LL失配在10°以内时,54.2%的患者在最初的术后x线片上能够达到PI-LL°。相比之下,只有20.5%的患者在MRI上匹配度大于100时达到了这一目标(p = 0.003, OR = 4.25)。结论:通过对症状性退行性椎体滑移患者的症状节段进行减压和内固定融合,我们能够实现PI-LL失配到10°以内。术前观察到的左左韧带丢失可能主要是体位性的,而不是结构性的。术后观察到的左腰椎矫正量可以通过术前腰椎伸展片和仰卧位矢状位MRI来预测。
{"title":"Sagittal spinopelvic malalignment in degenerative scoliosis patients: isolated correction of symptomatic levels and clinical decision-making.","authors":"Steven M Presciutti,&nbsp;Philip K Louie,&nbsp;Jannat M Khan,&nbsp;Bryce A Basques,&nbsp;Comron Saifi,&nbsp;Christopher J Dewald,&nbsp;Dino Samartzis,&nbsp;Howard S An","doi":"10.1186/s13013-018-0174-y","DOIUrl":"https://doi.org/10.1186/s13013-018-0174-y","url":null,"abstract":"<p><strong>Background: </strong>This study aims to determine if (1) loss of lumbar lordosis (LL), often associated with degenerative scoliosis (DS), is structural or rather largely due to positional factors secondary to spinal stenosis; (2) only addressing the symptomatic levels with a decompression and posterolateral fusion in carefully selected patients will result in improvement of sagittal malalignment; and (3) degree of sagittal plane correction achieved with such a local fusion could be predicted by routine pre-operative imaging.</p><p><strong>Methods: </strong>A retrospective study design with prospectively collected imaging data of a consecutive series of surgically treated DS patients who underwent decompression and instrumented fusion at only symptomatic levels was performed. Pre- and post-operative plain radiographs and pre-operative magnetic resonance imaging (MRIs) of the spinopelvic region were analyzed. LL, pelvic incidence (PI), pelvic tilt (PT), and sacral slope (SS) were assessed in all patients. As a requirement for the surgical strategy, all patients presented with a pre-operative PI-LL mismatch greater than 10<sup>°</sup>. Post-operative complications were assessed.</p><p><strong>Results: </strong>Pre-operative MRIs and lumbar extension radiographs revealed a mean LL of 42<sup>°</sup> (range 10-66<sup>°</sup>) and 48<sup>°</sup> (range 20-74<sup>°</sup>), respectively, in 68 patients (mean follow-up 29 months). LL post-operatively was corrected to a mean PI-LL of 10<sup>°</sup>. Of patients who achieved PI-LL mismatch within 10<sup>o</sup> on their pre-operative extension lateral lumbar radiographs, 62.5% were able to maintain a PI-LL mismatch within 10<sup>°</sup> on their initial post-operative films. Only 37.5% were not able to achieve that mismatch on extension radiographs (<i>p</i> = 0.001, OR = 9.58). Similarly, 54.2% were able to achieve a PI-LL < 10<sup>°</sup> on initial post-operative radiographs, when pre-operative MRI revealed a PI-LL mismatch within 10<sup>°</sup>. In contrast, only 20.5% achieved that goal post-operatively if their mismatch was greater than 10<sup>o</sup> on their MRI (<i>p</i> = 0.003, OR = 4.25).</p><p><strong>Conclusion: </strong>With a decompression and instrumented fusion of only the symptomatic levels in symptomatic DS patients, we were able to achieve a PI-LL mismatch to within 10<sup>°</sup>. The loss of LL observed pre-operatively may be largely positional rather than structural. The amount of LL correction observed immediately after surgery can be predicted from pre-operative lumbar extension radiographs and supine sagittal MRI.</p>","PeriodicalId":21573,"journal":{"name":"Scoliosis and Spinal Disorders","volume":"13 ","pages":"28"},"PeriodicalIF":0.0,"publicationDate":"2018-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13013-018-0174-y","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36832276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Truncal changes in children with mild limb length inequality: a surface topography study. 轻度肢体长度不均等儿童的躯干改变:一项表面形貌研究。
Q1 Medicine Pub Date : 2018-12-18 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0173-z
Theodoros B Grivas, Konstantinos Angouris, Michail Chandrinos, Vasilios Kechagias

Background: Limb length Inequality (LLI) in children and adults may affect posture, gait, and several truncal parameters, and it can cause spinal scoliosis. In literature, however, there is a paucity of assessment of truncal and spinal changes due to mild LLI in children. This report presents children with LLI, and it aims to provide information in pelvic imbalance, spinal posture, and scoliotic curve, using surface topography analysis which is a novel methodological approach for this condition.

Study design: This is an ongoing prospective research study on patient series suffering LLI.

Material and method: Twenty children, attending the Scoliosis Clinic of the department, 7 boys, 13 girls, 9-15 years old, range 7.5-15, mean 15.5 years, having mild LLI, were assessed. The LLI was 0.5 to 2 cm, mean 1.2 cm. There was not any post-traumatic LLI. We evaluated the LLI in correlation to pelvic and spinal posture parameters. The 4D Formetric DIERS apparatus (4DF) was used for the surface topography assessment. The following were assessed: in the coronal plane, the coronal imbalance, the pelvic obliquity, the lateral deviation, and the 4DF scoliosis angle; in the sagittal plane, the sagittal imbalance, the 4DF kyphotic angle, the kyphotic apex, the 4DF lordotic angle, the lordotic apex, the pelvic tilt, and the trunk inclination; and in the transverse plane, the pelvis rotation, the pelvic torsion, the surface rotation, and the 4DF vertebral rotation. LLI was measured using a tape. The data were statistically analyzed, and reliability study for the LLI was also performed.

Results/discussion: The LLI was statistically significantly correlated to the 4DF reading of pelvis rotation, pelvic tilt (pelvic obliquity), and surface rotation. The scoliometer readings (angle trunk rotation ATR or trunk inclination ATI) in the lumbar region were statistically significantly correlated to the 4DF readings of pelvic tilt (pelvic obliquity). The normally symmetric truncal parameters were also statistically significantly changed (all these deviating from the line of gravity through the vertebral prominence). Interestingly, LLI was not correlated to the scoliosis angle and the scoliometer reading at the lumbar level.The following 4DF readings are presented: in the coronal plane, the coronal imbalance, pelvic obliquity, lateral deviation, and 4DF scoliosis angle; in the sagittal plane, the sagittal imbalance, kyphotic angle, kyphotic apex, lordotic angle, lordotic apex, pelvic tilt, and trunk inclination; and in the transverse plane, the pelvic rotation, pelvic torsion, surface rotation, and vertebral rotation.

Conclusions: Previous studies have reported the results after simulation of LLI in order to evaluate the effects on the pelvic balance and spinal posture parameters. This report is not a LLI simulation study but it presents the effects

背景:儿童和成人的肢体长度不平等(LLI)可能影响姿势、步态和一些躯干参数,并可能导致脊柱侧凸。然而,在文献中,缺乏对儿童轻度LLI引起的躯干和脊柱变化的评估。本报告介绍了患有LLI的儿童,目的是利用表面形貌分析提供骨盆失衡、脊柱姿势和脊柱侧凸曲线的信息,这是一种新的方法方法。研究设计:这是一项正在进行的针对LLI患者系列的前瞻性研究。材料与方法:选取在该科脊柱侧凸门诊就诊的20例轻度LLI患儿,其中男孩7例,女孩13例,年龄9 ~ 15岁,范围7.5 ~ 15岁,平均15.5岁。LLI为0.5 ~ 2cm,平均1.2 cm。没有任何创伤后LLI。我们评估了LLI与骨盆和脊柱姿势参数的关系。使用4D formmetric DIERS仪(4DF)进行表面形貌评估。评估以下指标:冠状面、冠状面不平衡、骨盆倾斜、侧偏和4DF侧凸角;矢状面为矢状面不平衡、4DF后凸角、后凸尖、4DF前凸角、前凸尖、骨盆倾斜、躯干倾斜;横切面为骨盆旋转、骨盆扭转、面旋转、4DF椎体旋转。LLI用卷尺测量。对数据进行统计分析,并对LLI进行信度研究。结果/讨论:LLI与骨盆旋转、骨盆倾斜(骨盆倾斜)和表面旋转的4DF读数有统计学显著相关。腰椎区的脊柱侧弯仪读数(角躯干旋转ATR或躯干倾斜ATI)与骨盆倾斜(骨盆倾角)的4DF读数具有统计学意义。正常对称的截骨参数也发生了统计学上的显著变化(所有这些参数都偏离了通过椎突的重力线)。有趣的是,LLI与脊柱侧凸角度和腰椎水平侧凸计读数无关。提供以下4DF读数:在冠状面,冠状面不平衡、骨盆倾斜、侧偏和4DF脊柱侧凸角;在矢状面,矢状面不平衡、后凸角、后凸尖、前凸角、前凸尖、骨盆倾斜、躯干倾斜;而在横切面上,盆腔旋转、盆腔扭转、表面旋转、椎体旋转。结论:为了评估LLI对骨盆平衡和脊柱姿势参数的影响,已有研究报道了LLI模拟后的结果。本报告不是LLI的模拟研究,但它提出了轻度LLI对LLI患儿主要枢机面截骨变化的影响。这些变化无疑不仅影响了站立的躯干姿态,而且影响了步态的经济性。由于轻度LLI影响骨盆平衡和脊柱姿势参数,我们的治疗方法是轻度LLI(小于2.0 cm)必须使用鞋抬高矫正,以平衡骨盆倾角,从而平衡脊柱姿势参数。
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引用次数: 12
Quality of life and patient satisfaction in bracing treatment of adolescent idiopathic scoliosis. 青少年特发性脊柱侧凸矫正治疗中的生活质量和患者满意度。
Q1 Medicine Pub Date : 2018-12-14 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0172-0
Lucas Piantoni, Carlos A Tello, Rodrigo G Remondino, Ernesto S Bersusky, Celica Menéndez, Corina Ponce, Susana Quintana, Felisa Hekier, Ida A Francheri Wilson, Eduardo Galaretto, Mariano A Noël

Background: Bracing is used as a valid non-surgical treatment for adolescent idiopathic scoliosis (AIS) to avoid progression of the deformity and thereby surgery. The effect of bracing treatment on quality of life of patients with AIS has been a topic of interest in the international literature. The aim of this study was to evaluate the quality of life and patient satisfaction during bracing treatment for AIS of a pediatric hospital.

Material and method: We assessed a total of 43 non-consecutive female patients (mean age at questionnaire, 13 years and 1 month and 10 years and 8 months to 14 years and 5 months; mean period of usage of brace, 1 year and 7 months), with adolescent idiopathic scoliosis (AIS), older than 10 years of age until skeletal maturity, with a Risser sign less than 3 and scoliosis between 20 and 45°, treated with thoracolumbosacral orthosis (TLSO) for a period longer than 6 months, and without other comorbidities or previous surgeries, were evaluated. The patients were administered a previously validated to Spanish questionnaire on quality of life (Brace Questionnaire (BrQ); Grivas TB et al.). BrQ is a validated tool and is considered a disease-specific instrument; its score ranges from 20 to 100 points, and higher BrQ scores are associated with better quality of life.

Results: The patients reported using the brace for a mean of 17.6 h daily and for a mean period of 1 year and 7 months at the time of the study. Overall, 72% of the study population reported to be in some way psychologically affected by the brace wearing, 56% felt their basic motor activities were affected, 54% felt socialization with their environment was affected, 46% considered their quality of life deteriorated due to pain, and 40% reported conflicts in the school environment.

Conclusion: Patients with AIS treated with bracing reported a negative impact (53.5% overall) on quality of life and treatment satisfaction in terms of psychological, motor, social, and school environment aspects. An interdisciplinary approach would be important for the integrated psychosocial care of these patients.

背景:支撑疗法是治疗青少年特发性脊柱侧凸(AIS)的一种有效的非手术疗法,可避免畸形发展,从而避免手术。支具治疗对 AIS 患者生活质量的影响一直是国际文献关注的话题。本研究旨在评估一家儿科医院的 AIS 患者在支具治疗期间的生活质量和满意度:我们共评估了 43 名非连续就诊的女性患者(问卷调查时的平均年龄为 13 岁零 1 个月和 10 岁零 8 个月至 14 岁零 5 个月;青少年特发性脊柱侧弯症(AIS)患者的平均使用时间为 1 年零 7 个月),年龄在 10 岁以上至骨骼发育成熟,里瑟征小于 3,脊柱侧弯角度在 20 至 45°之间,接受胸腰骶矫形器(TLSO)治疗的时间超过 6 个月,无其他合并症或既往手术。这些患者接受了一份先前经过验证的西班牙生活质量调查问卷(Brace Questionnaire (BrQ); Grivas TB et al.)。BrQ是一种经过验证的工具,被认为是一种针对特定疾病的工具;其分值从20分到100分不等,BrQ分值越高,生活质量越好:患者报告称,每天平均使用支具 17.6 小时,平均使用时间为 1 年零 7 个月。总体而言,72%的研究对象表示佩戴支具对他们的心理造成了一定影响,56%的研究对象认为他们的基本运动活动受到了影响,54%的研究对象认为他们与周围环境的社交受到了影响,46%的研究对象认为他们的生活质量因疼痛而下降,40%的研究对象表示他们与学校环境产生了冲突:结论:接受支具治疗的 AIS 患者在心理、运动、社交和学校环境方面对生活质量和治疗满意度产生了负面影响(总体比例为 53.5%)。跨学科方法对于这些患者的综合心理社会护理非常重要。
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引用次数: 0
Acute pancreatitis after major spine surgery: a case report and literature review. 脊柱大手术后急性胰腺炎1例报告及文献复习。
Q1 Medicine Pub Date : 2018-11-08 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0170-2
Daniela Ghisi, Alessandro Ricci, Sandra Giannone, Tiziana Greggi, Stefano Bonarelli

Background: Acute pancreatitis has been described as potential complication of both abdominal and non-abdominal surgeries. The pathogenetic mechanism underlying acute pancreatitis in spine surgery may include intraoperative hemodynamic instability causing prolonged splanchnic hypoperfusion, as well as mechanical compression of the pancreas due to scoliosis correction, with a higher risk in cases of more extended fusions, especially in young adults with lower body mass index (BMI).

Case presentation: We report here a case of postoperative acute pancreatitis with benign evolution in a young female patient after the first and second surgery of a two-stage correction of right thoracic idiopathic scoliosis.In December 2017, the patient underwent first-stage T4-L3 posterior arthrodesis with T7-T12 osteotomies and temporary magnetic bar. Intraoperative blood loss required massive transfusion. In the immediate postoperative period, the patient started reporting nausea/vomiting, abdominal pain at pressure, moderate meteorism, abdominal distension, hypoactive bowel sounds, and fever. Laboratory tests indicated a progressive increase in aspartate aminotransferase, alanine aminotransferase, serum amylase, lipase, phospho-creatine kinase, and reactive C-protein. A CT scan showed free abundant abdominal fluid in the hepatic, renal, pancreatic, and pelvic regions. After the diagnosis, a hypolipidic diet was initiated, and good hydration per os was maintained. After gastroenterologic consultation, somatostatin, rifaximin, and ursodehoxycholic acid were initiated and maintained for 8 days. In the following days, laboratory tests showed a slow but consistent decrease in liver and pancreatic enzymes until normalization. In January 2018, the patient underwent second-stage surgery with removal of magnetic bar, definitive posterior fusion, and instrumentation T4-L3. Laboratory tests showed a second, even more significant, increase in the amylase and lipase level and a moderate increase in the reactive C-protein. Therapy was maintained until complete normalization of amylase and lipase levels.

Conclusions: Early recognition of symptoms plays a key role in preventing severe morbidity after scoliosis surgery. When symptoms suggest abdominal complication, pancreatic and liver enzymes are to be evaluated for posing prompt diagnosis. Gastroenterologic consultation and eventual imaging are further steps in differential diagnosis and treatment of this rare complication.

背景:急性胰腺炎被认为是腹部和非腹部手术的潜在并发症。脊柱外科急性胰腺炎的发病机制可能包括术中血流动力学不稳定导致长时间的内脏灌注不足,以及脊柱侧凸矫正导致胰腺的机械压迫,在融合更广泛的情况下风险更高,特别是在身体质量指数(BMI)较低的年轻人中。病例介绍:我们在此报告一例年轻女性患者在第一次和第二次手术后的良性演变急性胰腺炎右胸特发性脊柱侧凸两期矫正。2017年12月,患者接受了一期T4-L3后路关节融合术、T7-T12截骨术和临时磁棒。术中失血需要大量输血。术后即刻,患者开始出现恶心/呕吐、压痛腹痛、中度眩晕、腹胀、肠音减退和发热。实验室检查显示天冬氨酸转氨酶、丙氨酸转氨酶、血清淀粉酶、脂肪酶、磷酸肌酸激酶和反应性c蛋白逐渐升高。CT扫描显示肝脏、肾脏、胰腺和盆腔均有大量腹腔积液。诊断后,开始低脂饮食,并保持良好的水合作用。胃肠病学会诊后,开始使用生长抑素、利福昔明和熊去氧胆酸并维持8天。在接下来的几天里,实验室检查显示肝脏和胰腺酶缓慢而持续地下降,直到恢复正常。2018年1月,患者接受了二期手术,切除了磁棒,进行了明确的后路融合,并进行了T4-L3内固定。实验室测试显示,淀粉酶和脂肪酶水平第二次(甚至更显著)增加,反应性c蛋白略有增加。治疗一直持续到淀粉酶和脂肪酶水平完全正常化。结论:早期识别症状对预防脊柱侧凸术后严重并发症起关键作用。当症状提示腹部并发症时,应检查胰酶和肝酶,以便及时诊断。胃肠病学咨询和最终影像学检查是鉴别诊断和治疗这种罕见并发症的进一步步骤。
{"title":"Acute pancreatitis after major spine surgery: a case report and literature review.","authors":"Daniela Ghisi,&nbsp;Alessandro Ricci,&nbsp;Sandra Giannone,&nbsp;Tiziana Greggi,&nbsp;Stefano Bonarelli","doi":"10.1186/s13013-018-0170-2","DOIUrl":"https://doi.org/10.1186/s13013-018-0170-2","url":null,"abstract":"<p><strong>Background: </strong>Acute pancreatitis has been described as potential complication of both abdominal and non-abdominal surgeries. The pathogenetic mechanism underlying acute pancreatitis in spine surgery may include intraoperative hemodynamic instability causing prolonged splanchnic hypoperfusion, as well as mechanical compression of the pancreas due to scoliosis correction, with a higher risk in cases of more extended fusions, especially in young adults with lower body mass index (BMI).</p><p><strong>Case presentation: </strong>We report here a case of postoperative acute pancreatitis with benign evolution in a young female patient after the first and second surgery of a two-stage correction of right thoracic idiopathic scoliosis.In December 2017, the patient underwent first-stage T4-L3 posterior arthrodesis with T7-T12 osteotomies and temporary magnetic bar. Intraoperative blood loss required massive transfusion. In the immediate postoperative period, the patient started reporting nausea/vomiting, abdominal pain at pressure, moderate meteorism, abdominal distension, hypoactive bowel sounds, and fever. Laboratory tests indicated a progressive increase in aspartate aminotransferase, alanine aminotransferase, serum amylase, lipase, phospho-creatine kinase, and reactive C-protein. A CT scan showed free abundant abdominal fluid in the hepatic, renal, pancreatic, and pelvic regions. After the diagnosis, a hypolipidic diet was initiated, and good hydration per os was maintained. After gastroenterologic consultation, somatostatin, rifaximin, and ursodehoxycholic acid were initiated and maintained for 8 days. In the following days, laboratory tests showed a slow but consistent decrease in liver and pancreatic enzymes until normalization. In January 2018, the patient underwent second-stage surgery with removal of magnetic bar, definitive posterior fusion, and instrumentation T4-L3. Laboratory tests showed a second, even more significant, increase in the amylase and lipase level and a moderate increase in the reactive C-protein. Therapy was maintained until complete normalization of amylase and lipase levels.</p><p><strong>Conclusions: </strong>Early recognition of symptoms plays a key role in preventing severe morbidity after scoliosis surgery. When symptoms suggest abdominal complication, pancreatic and liver enzymes are to be evaluated for posing prompt diagnosis. Gastroenterologic consultation and eventual imaging are further steps in differential diagnosis and treatment of this rare complication.</p>","PeriodicalId":21573,"journal":{"name":"Scoliosis and Spinal Disorders","volume":"13 ","pages":"24"},"PeriodicalIF":0.0,"publicationDate":"2018-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1186/s13013-018-0170-2","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"36747608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 5
Retraction Note: Brace classification study group (BCSG): part one - definitions and atlas. 撤回注:支架分类研究组(BCSG):第一部分定义和图谱。
Q1 Medicine Pub Date : 2018-11-07 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0171-1
Theodoros B Grivas, Jean Claude de Mauroy, Grant Wood, Manuel Rigo, Michael Timothy Hresko, Tomasz Kotwicki, Stefano Negrini

[This retracts the article DOI: 10.1186/s13013-016-0102-y.].

[本文撤回文章DOI: 10.1186/s13013-016-0102-y.]。
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引用次数: 1
When and how to discontinue bracing treatment in adolescent idiopathic scoliosis: results of a survey. 青少年特发性脊柱侧凸何时及如何停止支具治疗:一项调查结果。
Q1 Medicine Pub Date : 2018-10-26 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0158-y
Lucas Piantoni, Carlos A Tello, Rodrigo G Remondino, Ida A Francheri Wilson, Eduardo Galaretto, Mariano A Noel

Background: Currently, there is little consensus on how or when to discontinue bracing in adolescent idiopathic scoliosis (AIS). An expert spine surgeon national survey could aid in elucidate discontinuation of the brace.Few data have been published on when and how to discontinue bracing treatment in patients with AIS resulting in differences in the management of the condition. The aim of this study was to characterize decision-making of surgeons in the management of bracing discontinuation in AIS.

Methods: An original electronic survey consisting of 12 multiple choice questions was sent to all the members of the National Spine Surgery Society (497 surveyed). Participants were asked about their type of medical practice, years of experience in the field, society memberships, type of brace they usually prescribed, average hours of daily brace wearing they recommended, and how and when they indicated bracing discontinuation as well as the clinical and/or imaging findings this decision was based on. Exclusion criteria include brace discontinued because of having developed a curve that warranted surgical treatment.

Results: Of a total of 497 surgeons, 114 responded the survey (22.9%). 71.9% had more than 5 years of experience in the specialty, and 51% mainly treated pediatric patients. Overall, 95.5% of the surgeons prescribed the thoracolumbosacral orthosis (TLSO), indicated brace wearing for a mean of 20.6 h daily. Regarding bracing discontinuation, indicated gradual brace weaning, a decision 93.9% based on anterior-posterior (AP) and lateral radiographs of the spine and physical examination, considered a Risser ≥ IV and ≥ 24 months post menarche.

Conclusions: The results of this study provide insight in the daily practice of spine surgeons regarding how and when they discontinue bracing in AIS. The decision of bracing discontinuation is based on AP/lateral spinal radiographs and physical examination, Risser ≥ IV, regardless of Tanner stage, and ≥ 24 months post menarche. Gradual weaning is recommended.

背景:目前,对于青少年特发性脊柱侧凸(AIS)如何或何时停止支具治疗,几乎没有共识。一项脊柱外科专家全国调查可以帮助阐明支架的停用。关于AIS患者何时以及如何停止支具治疗的数据很少,这导致了病情管理的差异。本研究的目的是描述外科医生在处理AIS患者支具中断时的决策。方法:向全国脊柱外科学会所有会员(497名)发送一份包含12道选择题的原始电子调查。参与者被问及他们的医疗实践类型,在该领域的多年经验,社会会员资格,他们通常处方的支架类型,他们建议的平均每天佩戴支架的时间,以及他们如何以及何时表示支架停止以及这一决定是基于临床和/或成像结果。排除标准包括支架因发生弯曲需要手术治疗而停用。结果:497名外科医生中,有114名回复调查,占22.9%。71.9%的医生有5年以上的专业经验,51%的医生主要治疗儿科患者。总的来说,95.5%的外科医生开了胸腰骶矫形器(TLSO),指示支架佩戴平均每天20.6小时。关于支架的停用,93.9%的决定基于脊柱的前后位(AP)和侧位x线片以及体格检查,考虑Risser≥IV和≥24个月的月经初潮。结论:本研究的结果为脊柱外科医生在AIS中如何以及何时停止支具的日常实践提供了见解。支具停用的决定是基于AP/侧位脊柱x线片和体格检查,Risser≥IV,不论Tanner分期,月经初潮后≥24个月。建议逐渐断奶。
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引用次数: 4
The association of high-intensity zones on MRI and low back pain: a systematic review. MRI高强度区与腰痛的关联:一项系统综述。
Q1 Medicine Pub Date : 2018-10-20 eCollection Date: 2018-01-01 DOI: 10.1186/s13013-018-0168-9
Masatoshi Teraguchi, Rita Yim, Jason Pui-Yin Cheung, Dino Samartzis

Background: Magnetic resonance imaging (MRI) of the lumbar spine is commonly used to identify the source of low back pain (LBP); however, its use has been questionable. Throughout the years, numerous lumbar phenotypes (e.g., endplate abnormalities, Modic changes, black disc) have been studied as possible pain generators. High-intensity zones (HIZs) are of particular interest as they may represent annular tears. However, for over three decades, there has been heated debate as to whether these imaging biomarkers are synonymous with LBP. Therefore, the following study addressed a systematic review of the reported literature addressing the relationship of HIZs and LBP.

Methods: A systematic review was conducted via MEDLINE, SCOPUS, Cochrane, PubMed, PubMed Central, EMBASE via Ovid, and Web of Science with the following search terms: "HIZ," "high intensity zone," or "high intensity zones" and "low back pain," "pain," "lumbago," and/or "sciatica." Specific exclusion criteria were also maintained. Two independent reviewers searched the literature, selected the studies, and extracted the data.

Results: We identified six studies from our search strategy that met the inclusion criteria from a total of 756 possible studies. One cross-sectional population-based study and five comparison studies were identified, which provided information regarding the prevalence of HIZs. The prevalence of HIZs was 3 to 61% in subjects with LBP and 2 to 3% in subjects without LBP. Only three studies suggested a significant association between the presence of HIZ and LBP with or without sciatica.

Conclusions: Our systematic review has found evidence that HIZs may be a possible risk factor for LBP; however, a mismatch of the clinical relevance of HIZs between studies still remains. The available evidence is limited by small sample size, heterogeneous study populations, and lack of standardized imaging methods for phenotyping. HIZs may be important lumbar biomarkers that demand further investigation and should be considered in the global imaging assessment of the spine, which may have immense clinical utility. Further large-scale studies with standardized imaging and classification techniques as well as the assessment of patterns of HIZs are necessary to better understand their role with LBP development.

背景:腰椎磁共振成像(MRI)通常用于识别腰痛(LBP)的来源;然而,它的使用一直受到质疑。多年来,许多腰椎表型(如终板异常、Modic改变、黑椎间盘)被研究为可能的疼痛产生源。高强度带(HIZs)是特别有趣的,因为它们可能代表环状撕裂。然而,30多年来,关于这些成像生物标志物是否等同于LBP一直存在激烈的争论。因此,下面的研究对报道的有关HIZs和LBP关系的文献进行了系统回顾。方法:通过MEDLINE、SCOPUS、Cochrane、PubMed、PubMed Central、EMBASE via Ovid和Web of Science进行系统综述,检索词为:“HIZ”、“高强度区”或“高强度区”和“腰痛”、“疼痛”、“腰痛”和/或“坐骨神经痛”。还保留了具体的排除标准。两名独立审稿人检索文献,选择研究,提取数据。结果:我们从756项可能的研究中确定了6项符合纳入标准的研究。确定了一项基于人群的横断面研究和五项比较研究,这些研究提供了有关HIZs患病率的信息。腰痛患者中HIZs患病率为3% ~ 61%,无腰痛患者中患病率为2% ~ 3%。只有三项研究表明HIZ和腰痛有或没有坐骨神经痛之间存在显著的关联。结论:我们的系统评价发现有证据表明HIZs可能是LBP的危险因素;然而,研究之间对HIZs临床相关性的不匹配仍然存在。现有的证据受到样本量小、研究人群异质性以及缺乏标准化的表型成像方法的限制。HIZs可能是重要的腰椎生物标志物,需要进一步研究,应该在脊柱的整体成像评估中考虑,这可能具有巨大的临床应用价值。为了更好地了解HIZs在腰痛发展中的作用,有必要进一步开展大规模研究,采用标准化的成像和分类技术,以及评估HIZs的模式。
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引用次数: 30
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Scoliosis and Spinal Disorders
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