Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.069
Xiaoling Fu, Shuangshuang Liang
{"title":"Sphingosine 1-phosphate suppresses the viability and estradiol secretion of mouse granulosa cells by activating G?12/13-YAP signaling","authors":"Xiaoling Fu, Shuangshuang Liang","doi":"10.2306/scienceasia1513-1874.2023.069","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.069","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136258669","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Evaluation of the agronomic and genotypic diversity of Thailand local rice (Oryza sativa L.) varieties under lowland conditions","authors":"Possawat Narumol, Witthawad Phormmard, Wanchana Aesomnuk, Tanee Sreewongchai, Siwaret Arikit, Chanate Malumpong","doi":"10.2306/scienceasia1513-1874.2023.074","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.074","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136258665","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2022.130
Y. Duan, Ting Wang, Shan Wu, Dong Liu, J. Zhao, Bin Liu
: This study aimed to investigate the role of the phosphatidylinositol 3-kinase / protein kinase B (PI3K / Akt) signaling pathway in the pulmonary vascular remodeling (PVR) of pulmonary arterial hypertension (PAH) in rats. A PAH model in rats was established through a left pneumonectomy and monocrotaline (MCT) injection, using the transglutaminase 2 (TG2) inhibitor cystamine dihydrochloride for intervention. Thirty healthy male Sprague Dawley rats were randomized into a control group, a model group, and an intervention group ( n = 10 for each group). The mean pulmonary arterial pressure (mPAP) was measured in all groups after 35 days, and the right ventricular hypertrophy index (RVHI) was calculated. Hematoxylin and eosin and lung elastic-fiber staining were used on the rats’ lung tissue in all three groups. The changes in pulmonary blood vessels and lung tissue force and the percentage of medial hypertrophy of small pulmonary arteries (WT%), vessel wall area to total area ratio (WA%), and the neointimal proliferation degree were observed. The Akt messenger RNA (mRNA) expression levels of lung tissues in all three groups were measured using a real-time polymerase chain reaction (RT-PCR) assay, and the protein expression levels of Akt and phosphorylated Akt (p-Akt) in all three groups were measured using a Western blot assay. The results indicated that the PI3K / Akt signaling pathway might play a substantial role in inhibiting pulmonary vascular remodeling (PVR) following intervention with a TG2 inhibitor.
{"title":"The role of the phosphatidylinositol 3-kinase/protein kinase B signaling pathway in the pulmonary vascular remodeling of pulmonary arterial hypertension in rats","authors":"Y. Duan, Ting Wang, Shan Wu, Dong Liu, J. Zhao, Bin Liu","doi":"10.2306/scienceasia1513-1874.2022.130","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2022.130","url":null,"abstract":": This study aimed to investigate the role of the phosphatidylinositol 3-kinase / protein kinase B (PI3K / Akt) signaling pathway in the pulmonary vascular remodeling (PVR) of pulmonary arterial hypertension (PAH) in rats. A PAH model in rats was established through a left pneumonectomy and monocrotaline (MCT) injection, using the transglutaminase 2 (TG2) inhibitor cystamine dihydrochloride for intervention. Thirty healthy male Sprague Dawley rats were randomized into a control group, a model group, and an intervention group ( n = 10 for each group). The mean pulmonary arterial pressure (mPAP) was measured in all groups after 35 days, and the right ventricular hypertrophy index (RVHI) was calculated. Hematoxylin and eosin and lung elastic-fiber staining were used on the rats’ lung tissue in all three groups. The changes in pulmonary blood vessels and lung tissue force and the percentage of medial hypertrophy of small pulmonary arteries (WT%), vessel wall area to total area ratio (WA%), and the neointimal proliferation degree were observed. The Akt messenger RNA (mRNA) expression levels of lung tissues in all three groups were measured using a real-time polymerase chain reaction (RT-PCR) assay, and the protein expression levels of Akt and phosphorylated Akt (p-Akt) in all three groups were measured using a Western blot assay. The results indicated that the PI3K / Akt signaling pathway might play a substantial role in inhibiting pulmonary vascular remodeling (PVR) following intervention with a TG2 inhibitor.","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68621778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2022.145
K. Sitlaothaworn, T. Budsabun, Manussawee Dechkla, P. Yukphan, S. Tanasupawat, A. Savarajara
{"title":"Identification and plant growth-promoting activity of endophytic bacteria from sugarcane roots and genome analysis of Gluconacetobacter strain PS25","authors":"K. Sitlaothaworn, T. Budsabun, Manussawee Dechkla, P. Yukphan, S. Tanasupawat, A. Savarajara","doi":"10.2306/scienceasia1513-1874.2022.145","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2022.145","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68621986","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.014
Mehbuba Nur Protha, Therathep Srisutjarit, A. Dey, S. Maitra, Jean‐François Hernandez, M. Tantisira, Yingrak Boondam, Narawut Pakaprot, B. Vincent
{"title":"The standardized Centella asiatica extract ECa 233 regulates the catalytic activities of ?APP-cleaving secretases in human cell lines","authors":"Mehbuba Nur Protha, Therathep Srisutjarit, A. Dey, S. Maitra, Jean‐François Hernandez, M. Tantisira, Yingrak Boondam, Narawut Pakaprot, B. Vincent","doi":"10.2306/scienceasia1513-1874.2023.014","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.014","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68622564","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.017
V. Dummee, Suhailar Sma-air, Suksiri Chooklin, Thanongsak Chanmethakul, R. Ritchie
{"title":"Photosynthesis and photosynthetic electron transport in the soft coral Sarcophyton spp","authors":"V. Dummee, Suhailar Sma-air, Suksiri Chooklin, Thanongsak Chanmethakul, R. Ritchie","doi":"10.2306/scienceasia1513-1874.2023.017","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.017","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68622952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.041
Li-li Guo, Yinling Li, Shuang Wen, W. jun Liu, Lei Yang, Yu Wan, Jia xin Liu, Wen e Zhao, Shu-Wei Li
{"title":"Shikonin inhibits ER stress in vascular endothelial cells, when induced by H2O2, and promotes vascular regeneration","authors":"Li-li Guo, Yinling Li, Shuang Wen, W. jun Liu, Lei Yang, Yu Wan, Jia xin Liu, Wen e Zhao, Shu-Wei Li","doi":"10.2306/scienceasia1513-1874.2023.041","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.041","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68624172","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.048
Shenglun Liu, Y. Ge, Fang Tian
{"title":"A sixth-order finite difference method for solving the generalized Burgers-Fisher and generalized Burgers-Huxley equations","authors":"Shenglun Liu, Y. Ge, Fang Tian","doi":"10.2306/scienceasia1513-1874.2023.048","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.048","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68626226","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2306/scienceasia1513-1874.2023.067
Nattaporn Klykleung, Hirotaka Matsuo, M. Iwatsuki, Yōko Takahashi, S. Ōmura, Masahiro Yuki, T. Kudo, M. Ohkuma, R. Luechapudiporn, S. Tanasupawat, T. Nakashima
{"title":"Genomic analysis and physicochemical screening of ikarugamycin, fumaquinone, and a new compound, pudicin from Streptomyces sp. 3MP-14","authors":"Nattaporn Klykleung, Hirotaka Matsuo, M. Iwatsuki, Yōko Takahashi, S. Ōmura, Masahiro Yuki, T. Kudo, M. Ohkuma, R. Luechapudiporn, S. Tanasupawat, T. Nakashima","doi":"10.2306/scienceasia1513-1874.2023.067","DOIUrl":"https://doi.org/10.2306/scienceasia1513-1874.2023.067","url":null,"abstract":"","PeriodicalId":21577,"journal":{"name":"Scienceasia","volume":null,"pages":null},"PeriodicalIF":1.2,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"68626662","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"综合性期刊","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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