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Meta-Analysis and Systematic Review of the Relationship between Cervical Lesions, HPV and Vaginal Community State Type 宫颈病变、HPV和阴道群落状态类型关系的meta分析和系统综述
Pub Date : 2022-07-01 DOI: 10.21276/ssr-iijls.2022.8.4.3
Jiaqi Pan, Zhiting Jiang, Yang Liu, Soumee Das, Xin Yu, Jifang Shi
Background: Chronic HPV infection is a precursor of cervical cancer, which is largely caused by dysregulation of vaginal flora and other factors like abnormal H 2 O 2 , neuraminidase and insufficient vaginal hygiene. The relationship between HPV-induced cancer and vaginal microbiota is involved in the viral chronicity and also influences the disease prognosis. A meta-analysis system was used to evaluate the relationship between cervical lesions, HPV and vaginal microenvironment. Methods: PubMed, Web of Science, Cochrane and Embase databases were searched for relevant literature published from 2016 to December 2020. According to the inclusion and exclusion criteria, literature screening, data extraction and quality evaluation were carried out, and stata16 statistical software was used for Meta-analysis and systematic evaluation. Results: The overall relative risk of CST in 95% CI: 0.76-1.4, LSIL group compared with normal cytology group was 0.81. The overall relative risk of CST in the HSIL group and cervical cancer group was 0.77 and 1.26, respectively. It was found that there was publication bias in the HPV positive group (p-value of Begg and Egger were 0.067 and 0.247) and cervical cancer group (p-value of Begg and Egger were 0.677 and 0.457 respectively). There was a significant difference in CST III between HPV positive group and the LSIL group. Conclusion: Cervical lesions and HPV are related to the increase of vaginal microbial diversity, and HPV and LSIL groups are related to CST III, while HSIL and cervical cancer groups are related to CSTIV, which has a certain guiding significance for early clinical diagnosis, but further large-scale studies are needed to confirm our findings.
背景:慢性HPV感染是宫颈癌的先兆,主要是由阴道菌群失调、h2o2异常、神经氨酸酶、阴道卫生不充分等因素引起的。hpv致癌与阴道菌群的关系不仅涉及病毒的慢性性,还影响疾病的预后。采用meta分析系统评价宫颈病变、HPV与阴道微环境的关系。方法:检索PubMed、Web of Science、Cochrane和Embase数据库2016年至2020年12月发表的相关文献。按照纳入和排除标准进行文献筛选、资料提取和质量评价,采用stata16统计软件进行meta分析和系统评价。结果:CST的总体相对危险度(95% CI)为0.76-1.4,LSIL组与正常细胞学组相比为0.81。HSIL组和宫颈癌组CST的总相对危险度分别为0.77和1.26。发现HPV阳性组(Begg和Egger的p值分别为0.067和0.247)和宫颈癌组(Begg和Egger的p值分别为0.677和0.457)存在发表偏倚。HPV阳性组与LSIL组的CSTⅲ比较,差异有统计学意义。结论:宫颈病变和HPV与阴道微生物多样性增加有关,HPV和LSIL组与CST III相关,而HSIL和宫颈癌组与CSTIV相关,对临床早期诊断有一定的指导意义,但需要进一步的大规模研究来证实我们的发现。
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引用次数: 0
Geographical Distribution of Sageraea laurina Dalzell 标题月桂草的地理分布
Pub Date : 2022-07-01 DOI: 10.21276/ssr-iijls.2022.8.4.4
B. S. Kale, S. Khairnar
Background: The Western Ghats is one of the Mega Biodiversity hot spots at the global level due to its high number of endemic plant species. That plant species, especially the endemics, have been reported and published in Red Data Book regularly. Sageraea laurina Dalzell. belongs to the plant family Annonacea. It is endemic to Western Ghats of India. The International Union for Conservation of Nature (IUCN) provided the status of this plant which is present in the Western Ghats. This is coming under near threat in the Western Ghats. The present distribution of S. laurina is only restricted to the Maharashtra, Goa, Karnataka, Kerala and Tamil Nadu states only. Methods: For primary data collection used repeated surveys of some areas under study using GPS. For secondary data collection used different literature such as Floras, database and herbarium consultation from BSI and ARI, Pune. Their taxonomy was re-investigated to confirm their taxonomic distinctness and Identification and classification of S. laurina Dalzell by using different Floras. Results: During the study, 118 different GPS localities were noted in the Western Ghats of India. The population distribution of this species covered the Northern (81%), Central (16%), and Southern (3%) Western Ghats of India. Conclusion: In the present study, we are generating primary and secondary data to stand a species in the IUCN category. Generated data used for conservation of this species. The major goal of the species recovery programme will be to re-establish the populations within their natural habitat
背景:西高止山脉因其大量特有植物物种而成为全球生物多样性的热点地区之一。这些植物物种,特别是地方性植物,已定期在《红皮书》中报告和出版。牡丹。番荔枝属植物科。它是印度西高止山脉特有的。国际自然保护联盟(IUCN)提供了这种植物的现状,它存在于西高止山脉。这在西高止山脉受到了威胁。目前的分布仅限于马哈拉施特拉邦、果阿邦、卡纳塔克邦、喀拉拉邦和泰米尔纳德邦。方法:利用GPS对部分研究区域进行重复调查,收集原始资料。对于二次数据收集,使用不同的文献,如植物区系、数据库和植物标本馆咨询来自BSI和ARI,浦那。对它们的分类学进行重新研究,以确定它们的分类独特性,并利用不同的区系对月桂花进行鉴定和分类。结果:在研究期间,在印度西高止山脉发现了118个不同的GPS位置。种群分布覆盖印度北部(81%)、中部(16%)和南部(3%)西高止山脉。结论:在目前的研究中,我们正在生成一个物种在IUCN分类中的第一手和第二手数据。生成用于该物种保护的数据。物种恢复方案的主要目标将是在其自然栖息地内重新建立种群
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引用次数: 0
Efficacy of Benson’s Relaxation Technique on Reduction of Pain and Anxiety among Post Cesarean Mothers 本森放松法减轻剖宫产后产妇疼痛和焦虑的疗效观察
Pub Date : 2022-07-01 DOI: 10.21276/ssr-iijls.2022.8.4.1
Pooja Prakash Morabad, Savita S. Angadi, Deelip Natekar
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引用次数: 1
Hope and Quality of the life of People living with HIV: A Cross-Sectional Study at ART Center, Bagalkot, Karnataka 卡纳塔克邦巴加尔科特ART中心的艾滋病毒感染者的希望和生活质量横断面研究
Pub Date : 2022-05-01 DOI: 10.21276/ssr-iijls.2022.8.3.2
Kavita Patil, Shriharsha C, Deelip Natekar
Background: HIV/AIDS emerged as the most important public health issue of the late twentieth and early twenty-first centuries. Hope & Quality of life (QoL) of People living with HIV/AIDS are affected by multiple socio-demographic variables as a major predictor of Hope & QoL. Methods: This cross-sectional descriptive survey research design included a sample of 430 PLHIV attending the ART centre, District Government Hospital, Bagalkot. Data were collected using the self-report method and Hospital records by socio-demographic questionnaire, Herths Hope Scale and WHO QOLHIV-BREF scale. Pearson's Correlations, chi-square test and multiple linear regression analysis were used. Results: A significant positive association was found between Hope and QoL among PLHIV (r= 0.483, p<0.001 ). A significant regression equation (F 429, 42= 1.842, R 2 =0.167, p<0.01 ). Married status i.e. married, Occupation i.e. doing Labor work has positively and 3 rd and 4 th clinical-stage have negatively predicted Hope of PLHIV. A Non significant regression equation (F 429,42 =1.37, R 2 =0.13, p<0.05 ). Being a private employee had positively and Heterosexual had negatively predicted and remained determinants have not predicted QoL among PLHIV and there was a significant association found between marital status and remained variables are not associated with Hope. There was a significant negative relationship found between Family monthly income and a positive relationship found between the duration of HIV and QoL. Marital status is significantly associated with QoL. Conclusions: The overall findings reveals that a significant positive correlation between Hope and QoL among PLHIV. There was a significant association found between marital status with Hope. There was a significant negative relationship found between Family monthly income and positive relationship found Duration of HIV and QoL.
背景:艾滋病毒/艾滋病成为20世纪末和21世纪初最重要的公共卫生问题。艾滋病毒/艾滋病患者的希望和生活质量(QoL)受多个社会人口变量的影响,是希望和生活质量的主要预测因子。方法:采用横断面描述性调查研究设计,纳入在巴加尔科特区政府医院ART中心就诊的430例hiv感染者。采用自我报告法和医院病历,采用社会人口调查问卷、Herths Hope量表和WHO QOLHIV-BREF量表收集数据。采用Pearson相关、卡方检验和多元线性回归分析。结果:PLHIV患者Hope与QoL呈显著正相关(r= 0.483, p<0.001)。有显著回归方程(f429, 42= 1.842, r2 =0.167, p<0.01)。婚姻状况(已婚)、职业(从事劳动工作)为阳性,第三和第四个临床阶段为阴性预测hiv的希望。A非显著性回归方程(f429,42 =1.37, r2 =0.13, p<0.05)。在hiv患者中,作为一名私人雇员对生活质量有正向预测,异性恋对生活质量有负向预测,其余的决定因素对生活质量没有预测,婚姻状况和剩余的变量之间存在显著的关联,与希望无关。家庭月收入与生活质量呈显著负相关,HIV持续时间与生活质量呈显著正相关。婚姻状况与生活质量显著相关。结论:总体结果显示hiv患者的Hope与QoL之间存在显著正相关。婚姻状况与希望之间存在着显著的联系。家庭月收入与HIV持续时间、生活质量呈显著负相关。
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引用次数: 0
Dietary Habits and Nutritional Status among Preschool Children: An Observational Study at Bagalkot 巴加尔科特学龄前儿童饮食习惯和营养状况:一项观察性研究
Pub Date : 2022-05-01 DOI: 10.21276/ssr-iijls.2022.8.3.1
Gundurao G. Chilapur, Deelip Natekar
Background: Knowing what eating habits are associated with a child's development can lead to better long-term health outcomes and improve dietary design interventions. We aimed to identify eating habits associated with the nutritional status of children between 3-6 years living in Chilapur Village of Bagalkot District. Methods: Dietary habits of preschool children were assessed with the aid of a structured score scale in an interview of mothers and fathers of preschool children. Anthropometric measurements like weight, height and mid-arm circumference have been taken to decide the nutritional status of preschool kids with help of Z rating received via WHO Anthro software. Results: Findings of the study reveals that 68% of preschool children had moderate dietary habits and 28% of them had poor eating habits and 4% of them had good eating habits. Nutritional Status assessed through anthropometric measurements shows that 39% of preschool children had moderate nutritional status according to their weight for age (≤-2 to +2 Score), 51% of preschool children had moderate nutritional status according to their height for age (≤-2 to +2 Score), and 48% of pre-school children had moderate nutritional status according to their Weight for height (≤-2 to +2 z score). A significant association was found between Dietary habits and Weight for age ( χ 2 = 8.69, p<0.05 ), Weight for height ( χ 2 = 9.12, p<0.05 ). A significant association was found between dietary habits and Family monthly income ( χ 2 = 10.58, p<0.05 ). Conclusion: Nutritional status of children aged between 3–6 years is of great health concern in India. A better nutritional diversity and meals variety and dietary styles characterized by intake of protein and calorie-rich diet seem beneficial for the growth of younger kids.
背景:了解哪些饮食习惯与儿童发育有关,可以带来更好的长期健康结果,并改进饮食设计干预措施。我们的目的是确定与巴加尔科特地区奇拉普尔村3-6岁儿童营养状况相关的饮食习惯。方法:采用结构化计分量表对学龄前儿童的父母进行访谈,对学龄前儿童的饮食习惯进行评估。采用了体重、身高和中臂围等人体测量方法,借助世卫组织anthroo软件获得的Z评级来确定学龄前儿童的营养状况。结果:研究结果显示,68%的学龄前儿童饮食习惯中等,28%的学龄前儿童饮食习惯不良,4%的学龄前儿童饮食习惯良好。通过人体测量评估的营养状况显示,39%的学龄前儿童按年龄体重营养状况为中等(≤-2 ~ +2 Score), 51%的学龄前儿童按年龄身高营养状况为中等(≤-2 ~ +2 Score), 48%的学龄前儿童按身高体重营养状况为中等(≤-2 ~ +2 z Score)。饮食习惯与年龄组体重(χ 2 = 8.69, p<0.05)、身高组体重(χ 2 = 9.12, p<0.05)显著相关。饮食习惯与家庭月收入有显著相关性(χ 2 = 10.58, p<0.05)。结论:印度3-6岁儿童的营养状况是一个值得关注的健康问题。更好的营养多样性和膳食多样性以及以摄入蛋白质和富含卡路里的饮食为特征的饮食方式似乎有利于幼儿的成长。
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引用次数: 0
Organoleptic and Nutritional Attributes of Chia and Soybean Based Instant Multigrain Sweet Mix Breakfast Cereal 中国大豆即食杂粮甜混合早餐麦片的感官和营养特性
Pub Date : 2022-05-01 DOI: 10.21276/ssr-iijls.2022.8.3.4
Varun Singh, L. Bala, S. Tiwari
Background : Breakfast is the most crucial meal after overnight fasting but the morning has the most rushed hours for working people. Ready to eat and ready to cook breakfast cereals are very popular these days that provide maximum nutrition with less effort than cooking breakfast cereals. Methods : Instant Multigrain sweet Mix breakfast cereals by using Chia in different proportion with cereals which varies accordingly, and Soybean with constant amount along with skimmed milk powder, sugar, brown sugar and golden syrup. Breakfast mixes were made with whole Chia seeds and secondary processed i.e. popped maize, puffed rice paddy and flaked wheat. Result s : After organoleptic evaluation by panel list by using 9 hedonic scales, 10% Chia seeds with other cereals and soybean combination could be used best quality instant multigrain sweet mix breakfast cereals with nutritionally adequate compared with other market brand product along with 6-month shelf life. Conclusion: Instant multigrain sweet mix breakfast cereals by using Chiahave essential nutrients that require in commercial breakfast cereals brands.
背景:早餐是通宵禁食后最重要的一餐,但对于劳动人民来说,早晨是最忙碌的时间。即食和即食早餐谷物现在非常受欢迎,它们比烹饪早餐谷物更容易提供最大的营养。方法:将奇亚籽按不同比例与相应比例的谷物、等量的大豆、脱脂奶粉、白砂糖、红糖、金糖浆混合成早餐谷物。早餐是用整个奇亚籽和二次加工制成的,比如炸玉米、膨化稻田和小麦片。结果:采用9种享乐量表的面板表法进行感官评价,10%奇亚籽与其他谷物和大豆组合可制成与其他市场品牌产品相比营养充足的优质即食杂粮甜混早餐麦片,保质期为6个月。结论:即食杂粮甜混早餐麦片具有商业早餐麦片品牌所需要的必需营养素。
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引用次数: 0
Review on the Therapeutic Protein Production in Plants 植物治疗性蛋白生产研究进展
Pub Date : 2022-05-01 DOI: 10.21276/ssr-iijls.2022.8.3.3
Shiksha Dwivedi, Y. Verma͙͙, A. Yadav, D. Kushwaha
The production of protein therapeutics in plants it is great potential for increasing, improving and developing the number of therapeutic protein production, therapeutic protein help for the prevention of diseases and treatments in animals and human transgenic plants are the most promising system for the production of a human therapeutic protein. The glycoproteins produced from plants are not the same as a native therapeutic proteins produced in mammals. But using the plants has more advantages such as the low cost and the large scale production is safe. Therefore biological active plant protein has become an alternative option to animal cells for the production of the therapeutic protein.
植物蛋白治疗剂的生产具有很大的潜力,增加、改进和发展治疗性蛋白的生产数量,治疗性蛋白有助于动物和人类疾病的预防和治疗,转基因植物是最有前途的一种人类治疗性蛋白的生产系统。从植物中产生的糖蛋白与在哺乳动物中产生的天然治疗蛋白不同。但使用该装置具有成本低、规模化生产安全等优点。因此,生物活性植物蛋白已成为替代动物细胞生产治疗性蛋白的一种选择。
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引用次数: 0
Study on Evaluation of Anaesthetic Pain Management in Day Care Surgery 日间护理手术麻醉疼痛处理的评价研究
Pub Date : 2022-05-01 DOI: 10.21276/ssr-iijls.2022.8.3.5
Soumee Das, Uday Kumar Panigrahi, Atreyee Choudhuri, J. V. Cardoza, F. Jaman, H. K. Rashid
Background: Daycare surgeries are those surgical procedures in which the patients are admitted and discharged on the same day. As daycare surgeries surged, there is a need to have an anaesthetic agent which can be efficient and also causes fewer side effects. This study effectively analyses the efficacy and safety profile of the two most popular anaesthetic agents used in daycare surgeries. Methods: This is a retrospective study that was conducted between January 2022 and March 2022. The included patients were between 25 years and 65 years old. The outcomes were based on several factors like the efficacy of the anaesthesia (based on 4-point scale, recovery time and appearance of any side effects. Results: The efficacy of the anaesthetic action was assessed by the 4-point scale of anaesthetic effect, which showed a better outcome with sevoflurane. The Recovery Time in Group 1 was 19.92±3.24 minutes while in Group 2 it was 25.04±3.03 minutes. The findings reveal that the numbers of patients with complications are more in Group 1 as compared to Group 2 patients. Conclusion: Daycare surgery has increased and so, there is need to find an anesthetic agent which can efficiently be used. Anaesthetic efficiency is quite higher in sevoflurane as compared to desflurane. In the case of each complication, sevoflurane proved to have lesser complications as compared to desflurane. Sevoflurane is a better alternative to desflurane in daycare surgery as the anaesthetic agent of choice.
背景:日托手术是指患者在同一天入院和出院的手术。随着日托手术的激增,需要一种既有效又副作用小的麻醉剂。本研究有效地分析了日托手术中两种最常用的麻醉剂的有效性和安全性。方法:这是一项回顾性研究,于2022年1月至2022年3月进行。纳入的患者年龄在25岁至65岁之间。结果基于几个因素,如麻醉效果(基于4分制),恢复时间和任何副作用的出现。结果:采用麻醉效果4分制评价麻醉作用效果,七氟醚麻醉效果较好。组1的恢复时间为19.92±3.24 min,组2的恢复时间为25.04±3.03 min。结果显示,与2组患者相比,1组患者出现并发症的数量更多。结论:日托手术增多,需要寻找一种有效使用的麻醉剂。七氟醚的麻醉效率比地氟醚高得多。在每种并发症的情况下,与地氟醚相比,七氟醚证明并发症较少。在日托手术中,七氟醚是一种比地氟醚更好的麻醉剂。
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引用次数: 0
Cytoprotective Effect of Dietary Squalene Supplementation on Experimentally Induced Cardiomyopathy in Rats 饲料中添加角鲨烯对实验性心肌病大鼠的细胞保护作用
Pub Date : 2022-03-01 DOI: 10.21276/ssr-iijls.2022.8.2.3
P. Srivastava, Agnivesh Gupta
{"title":"Cytoprotective Effect of Dietary Squalene Supplementation on Experimentally Induced Cardiomyopathy in Rats","authors":"P. Srivastava, Agnivesh Gupta","doi":"10.21276/ssr-iijls.2022.8.2.3","DOIUrl":"https://doi.org/10.21276/ssr-iijls.2022.8.2.3","url":null,"abstract":"","PeriodicalId":21836,"journal":{"name":"SSR Institute of International Journal of Life Sciences","volume":"2007 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82575255","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Relationship between PCOS with Infertility and Insulin Sensitivity: A Review 多囊卵巢综合征与不孕症与胰岛素敏感性的关系综述
Pub Date : 2022-03-01 DOI: 10.21276/ssr-iijls.2022.8.2.2
Soumee Das, Jifang Shi
{"title":"Relationship between PCOS with Infertility and Insulin Sensitivity: A Review","authors":"Soumee Das, Jifang Shi","doi":"10.21276/ssr-iijls.2022.8.2.2","DOIUrl":"https://doi.org/10.21276/ssr-iijls.2022.8.2.2","url":null,"abstract":"","PeriodicalId":21836,"journal":{"name":"SSR Institute of International Journal of Life Sciences","volume":"19 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81568106","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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SSR Institute of International Journal of Life Sciences
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