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Single-port laparoscopic surgery for cecum cancer with intussusception: a case report. 单孔腹腔镜手术治疗伴有肠套叠的盲肠癌:病例报告。
IF 0.7 Q4 SURGERY Pub Date : 2024-07-03 DOI: 10.1186/s40792-024-01962-2
Yuhei Oshima, Yasuhiro Ishiyama, Hiroto Tanaka, Tadatsugu Fujii, Naoto Okazaki, Toshimasa Ishii, Katuya Deguchi, Yasumitsu Hirano, Isamu Koyama

Background: Most adult cases of intussusception are caused by colorectal cancer, and emergency surgery is performed when symptoms such as abdominal pain and vomiting are present. The patient must customarily undergo both bowel decompression and radical surgery for colorectal cancer at the same time, and laparotomy is generally the procedure of choice.

Case presentation: An 86-year-old woman presented to our hospital with diarrhea and bloody stools. Preoperative examination revealed the presence of a cancerous tumor in the advanced part of the transverse colon and bowel intussusception. Radical surgery was successfully performed using the laparoscopic single-port technique through a small incision at the umbilical site to treat intussusception caused by cecum cancer.

Conclusions: With only one wound site at the umbilicus, this single-port laparoscopic approach is much less invasive than endoscopic surgery that requires four to five incision wounds to perform the procedure. Furthermore, the patient was discharged without major complications and this surgical technique could be of great benefit if established as a standard procedure in the future.

背景:大多数成人肠套叠病例都是由结直肠癌引起的,当出现腹痛和呕吐等症状时需要进行紧急手术。通常情况下,患者必须同时接受肠减压术和结直肠癌根治术,而开腹手术通常是首选:一名 86 岁的妇女因腹泻和血便来我院就诊。术前检查发现,横结肠晚期存在癌瘤,并有肠套叠。采用腹腔镜单孔技术,通过脐部小切口成功实施了根治手术,治疗了由盲肠癌引起的肠套叠:结论:这种单孔腹腔镜手术仅在脐部有一个伤口,与需要四到五个切口的内窥镜手术相比,创伤要小得多。此外,患者在出院时没有出现重大并发症,如果这种手术技术将来被确立为标准手术方法,将大有裨益。
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引用次数: 0
Hepatopancreatoduodenectomy with delayed division of the pancreatic parenchyma when utilizing a right lateral approach to the superior mesenteric artery. 利用肠系膜上动脉右外侧入路进行肝胰十二指肠切除术,延迟分割胰腺实质。
IF 0.7 Q4 SURGERY Pub Date : 2024-07-02 DOI: 10.1186/s40792-024-01965-z
Aoi Hayasaki, Naohisa Kuriyama, Benson Kaluba, Tatsuya Sakamoto, Haruna Komatsubara, Koki Maeda, Toru Shinkai, Daisuke Noguchi, Takahiro Ito, Kazuyuki Gyoten, Takehiro Fujii, Yusuke Iizawa, Akihiro Tanemura, Yasuhiro Murata, Masashi Kishiwada, Mitsunaga Narushima, Shugo Mizuno

Background: Hepatopancreatoduodenectomy (HPD) is a high-risk surgical procedure. Delayed division of the pancreatic parenchyma (DDPP) was reported as a novel technique in HPD for reducing postoperative pancreatic fistula. However, it is often difficult to dissect the pancreatic head nerve plexus while leaving the pancreatic parenchyma intact, particularly in patients with a bulky tumor with vascular invasion. Of the various reported approaches to the superior mesenteric artery, the right lateral approach can provide a useful surgical field to conduct DDPP in HPD.

Case presentation: A 78-year-old man visited a local clinic with itching and jaundice. Laboratory tests revealed elevated hepatobiliary enzyme, total bilirubin, and tumor markers. Enhanced computed tomography, endoscopic retrograde cholangiopancreatography, and intraductal ultrasonography of the bile duct were performed, and he was diagnosed with perihilar cholangiocarcinoma with invasion to the right hepatic artery (40 × 15 mm, Bismuth IIIa, cT3N0M0 cStage III). After neoadjuvant chemotherapy, he underwent left hepatectomy with caudate lobectomy, pancreatoduodenectomy, and combined resection of right hepatic artery using DDPP with a right lateral approach to the superior mesenteric artery. The pathological diagnosis was perihilar cholangiocarcinoma ypT3N1M0 ypStage IIIC, R0 resection. He was discharged on postoperative day 57 in good health and has been doing well for 6 months since the surgery.

Conclusions: We present an effective application of the right lateral approach to the superior mesenteric artery in DDPP during HPD. This procedure can provide a clear surgical field to easily divide the pancreatic head nerve plexus before transection of the pancreatic parenchyma.

背景:肝胰十二指肠切除术(HPD)是一种高风险外科手术。据报道,延迟分割胰腺实质(DDPP)是肝胰十二指肠切除术中减少术后胰瘘的一种新技术。然而,在保留胰腺实质完整的情况下剥离胰头神经丛通常很困难,尤其是对于有血管侵犯的巨大肿瘤患者。在已报道的各种肠系膜上动脉入路中,右外侧入路可为 HPD 的 DDPP 提供有用的手术视野:一名 78 岁的男性因皮肤瘙痒和黄疸到当地诊所就诊。实验室检查显示肝胆酶、总胆红素和肿瘤标志物升高。经增强计算机断层扫描、内镜逆行胰胆管造影和胆管导管内超声检查,他被诊断为肝周胆管癌,右肝动脉受侵(40 × 15 mm,铋Ⅲa,cT3N0M0 cStage III)。在接受新辅助化疗后,他接受了左肝切除术和尾状肝叶切除术、胰十二指肠切除术,并使用 DDPP 和肠系膜上动脉右侧入路联合切除了右肝动脉。病理诊断为肝周胆管癌 ypT3N1M0 ypⅡIC期,R0切除。他于术后第 57 天出院,健康状况良好,术后 6 个月来一直表现良好:结论:我们介绍了一种在 HPD 期 DDPP 中有效应用肠系膜上动脉右外侧入路的方法。该手术可提供清晰的手术视野,在横断胰腺实质之前轻松分割胰头神经丛。
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引用次数: 0
Visualization of cecal tumor by near-infrared laparoscopy and intraoperative colonoscopy. 通过近红外腹腔镜和术中结肠镜观察盲肠肿瘤。
IF 0.7 Q4 SURGERY Pub Date : 2024-07-01 DOI: 10.1186/s40792-024-01964-0
Kaori Watanabe, Hiroki Takahashi, Shuhei Uehara, Akira Kato, Yoshiaki Fujii, Takeshi Yanagita, Takuya Suzuki, Hajime Ushigome, Yuzo Maeda, Ryo Ogawa, Yoichi Matsuo, Akira Mitsui, Shuji Takiguchi

Background: In laparoscopic colorectal surgery, accurate localization of a tumor is essential for ensuring an adequate ablative margin. Therefore, a new method, near-infrared laparoscopy combined with intraoperative colonoscopy, was developed for visualizing the contour of a cecal tumor from outside of the bowel. The method was used after it was verified on a model that employed a silicone tube.

Case presentation: The patient was a 77-year-old man with a cecal tumor near the appendiceal orifice. Laparoscopy was used to clamp of the terminal ileum, and a colonoscope was then inserted through the anus to the cecum. The laparoscope in the normal light mode could not be used to identify the cecal tumor. However, a laparoscope in the near-infrared ray mode could clearly visualize the contour of the cecal tumor from outside of the bowel, and the tumor could be safely resected by a stapler. The histopathological diagnosis of the resected specimen was adenocarcinoma with an invasion depth of M and a clear negative margin.

Conclusions: This is the first report of the laparoscopic detection of the contour of a cecal tumor from outside the bowel. This technique is useful and safe for contouring tumors in laparoscopic colorectal surgery and can be used in various surgeries that combine endoscopy and laparoscopy.

背景:在腹腔镜结直肠手术中,肿瘤的准确定位对于确保足够的消融边缘至关重要。因此,我们开发了一种新方法,即近红外腹腔镜结合术中结肠镜,从肠外观察盲肠肿瘤的轮廓。该方法是在使用硅胶管的模型上验证后使用的:患者是一名 77 岁的男性,其盲肠肿瘤靠近阑尾口。使用腹腔镜钳夹回肠末端,然后将结肠镜通过肛门插入盲肠。正常光线模式下的腹腔镜无法识别盲肠肿瘤。然而,近红外线模式的腹腔镜可以从肠道外清楚地看到盲肠肿瘤的轮廓,并可以用订书机安全地切除肿瘤。切除标本的组织病理学诊断为腺癌,浸润深度为 M,阴性边缘清晰:这是首次报道从肠外通过腹腔镜检测盲肠肿瘤的轮廓。这项技术对腹腔镜结直肠手术中的肿瘤轮廓检测既实用又安全,可用于各种内镜和腹腔镜联合手术。
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引用次数: 0
Laparoscopic redo surgery for sigmoid volvulus following laparoscopic sigmoidectomy. 腹腔镜乙状结肠切除术后的乙状结肠肿物腹腔镜重做手术。
IF 0.7 Q4 SURGERY Pub Date : 2024-06-28 DOI: 10.1186/s40792-024-01961-3
Hideyuki Masui, Kenji Kawada, Susumu Inamoto, Toshiaki Wada, Yoshiharu Sakai, Kazutaka Obama

Background: Sigmoid volvulus (SV) is an acute abdominal condition characterized by torsion of the sigmoid colon around the mesentery, and often results in intestinal obstruction that may progress to bowel ischemia, necrosis, or perforation. Although SV commonly occurs due to predisposing factors like anatomic variations, age-related motility disorders, chronic constipation, and neurologic diseases, its incidence following sigmoid colon cancer surgery has rarely been reported. Herein, we report a rare case of recurrent SV following laparoscopic sigmoidectomy, which was successfully treated by laparoscopic redo surgery.

Case presentation: The patient was a 77-year-old man who had previously undergone laparoscopic sigmoidectomy for sigmoid colon cancer. Sixteen months postoperatively, he developed an incisional hernia at the umbilical site, which was treated with a laparoscopic repair using an intraperitoneal onlay mesh. After the hernia surgery, the patient had no anastomotic leakage or stenosis on regular follow-ups. However, 65 months after the first surgery, he presented with abdominal pain and distension. A computed tomography revealed that the remnant sigmoid colon was distended in a twisting manner around the anastomosis, leading to the diagnosis of SV. Although endoscopic de-torsion was successful, the SV recurred 2 months later, requiring elective laparoscopic redo surgery. The procedure involved resection of the sigmoid colon including the prior anastomosis with a left pararectal incision and DST re-anastomosis using a 25-mm circular stapler. The operation lasted 165 min with minimal bleeding and no complications. The postoperative course was uneventful. Pathological analysis confirmed fibrosis without malignancy. The patient remains well without recurrence of SV and anastomotic stenosis more than 5 years after surgery.

Conclusion: SV following sigmoid colon cancer surgery has rarely been reported. This case illustrates the potential need for prophylaxis against postoperative SV, especially in patients with long sigmoid colon undergoing laparoscopic surgery for colorectal cancer. Further, laparoscopic redo surgery following initial laparoscopic surgery for colorectal cancer can be performed with minimal invasiveness, especially if patient selection is properly managed.

背景:乙状结肠旋转(SV)是一种急腹症,其特征是乙状结肠围绕肠系膜发生扭转,通常会导致肠梗阻,并可能发展为肠道缺血、坏死或穿孔。虽然 SV 常见于解剖变异、与年龄相关的运动障碍、慢性便秘和神经系统疾病等易感因素,但乙状结肠癌手术后的发病率却鲜有报道。在此,我们报告了一例腹腔镜乙状结肠切除术后复发 SV 的罕见病例,该病例通过腹腔镜重做手术成功治愈:患者是一名 77 岁的男性,曾因乙状结肠癌接受过腹腔镜乙状结肠切除术。术后 16 个月,他出现了脐部切口疝,通过腹腔镜修补术使用腹腔内嵌网进行了治疗。疝气手术后,患者在定期随访中未发现吻合口渗漏或狭窄。然而,在第一次手术 65 个月后,他出现了腹痛和腹胀。计算机断层扫描显示,残余乙状结肠在吻合口周围以扭曲的方式胀大,因此被诊断为 SV。虽然内镜下扭转术很成功,但两个月后 SV 再次复发,需要进行择期腹腔镜重做手术。手术采用左侧直肠旁切口切除乙状结肠,包括之前的吻合口,并使用 25 毫米圆形订书机进行 DST 再吻合。手术历时 165 分钟,出血量极少,无并发症。术后恢复顺利。病理分析证实该患者已纤维化,无恶性肿瘤。该患者术后 5 年多未复发 SV 和吻合口狭窄,目前情况良好:结论:乙状结肠癌手术后出现 SV 的报道很少见。本病例说明了对术后 SV 进行预防的潜在必要性,尤其是对接受腹腔镜结直肠癌手术的乙状结肠较长的患者。此外,初次腹腔镜结直肠癌手术后的腹腔镜重做手术可以在微创的情况下进行,尤其是在患者选择管理得当的情况下。
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引用次数: 0
Laparoscopic liver resection for a patient of hepatocellular carcinoma with von Willebrand disease: a case report. 为一名伴有von Willebrand病的肝细胞癌患者实施腹腔镜肝脏切除术:病例报告。
IF 0.7 Q4 SURGERY Pub Date : 2024-06-27 DOI: 10.1186/s40792-024-01960-4
Oğuzhan Şal, Katsunori Sakamoto, Kei Tamura, Masahiko Honjo, Yusuke Nishi, Naotake Funamizu, Kohei Ogawa, Yasutsugu Takada

Background: The safety of laparoscopic hepatectomy for inherited coagulation disorders is unclear; however, the safety of open hepatectomy has been reported in several studies. Herein, we report the first case of a laparoscopic hepatectomy for a patient with von Willebrand Disease (VWD).

Case presentation: A 76-year-old male with a history of chronic hepatitis C and VWD type 2B was advised surgical resection of a 4 cm hepatocellular carcinoma in segment 7 of the liver. The patient was diagnosed with VWD in his 40 s due to gastrointestinal bleeding caused by gastric erosion. The von Willebrand factor (VWF) ristocetin cofactor activity was 30%, and VWF large multimer deficiency and increased ristocetin-induced platelet agglutination were observed. The preoperative platelet count was reduced to 3.5 × 104/μL; however, preoperative imaging findings had no evidence of liver cirrhosis, such as any collateral formations and splenomegaly. The indocyanine green retention rate at 15 min was 10%, and his Child-Pugh score was 5 (classification A). Perioperatively, VWF/factor VIII was administered in accordance with our institutional protocol. A laparoscopic partial hepatectomy of the right posterior segment was performed. The most bleeding during surgery occurred during the mobilization of the right lobe of the liver due to inflammatory adhesion between the retroperitoneum and the tumor. Bleeding during parenchymal transection was controlable. The duration of hepatic inflow occlusion was 65 min. The surgical duration was 349 min, and the estimated blood loss was 2150 ml. Four units of red blood cells and fresh frozen plasma were transfused at the initiation of parenchymal transection, and 10 units of platelets were transfused at the end of the parenchymal transection. On postoperative day 1, the transection surface drainage fluid became hemorrhagic, and emergency contrast-enhanced computed tomography showed extravasation in the greater omentum. Percutaneous transcatheter arterial embolization of the omental branch of the right gastroepiploic artery was performed. No further postoperative interventions were required. The patient was discharged on postoperative day 14.

Conclusion: The indications for laparoscopic hepatectomy in patients with VWD should be carefully considered, and an open approach may still be the standard approach for patients with VWD.

背景:腹腔镜肝切除术治疗遗传性凝血功能障碍的安全性尚不明确;但已有多项研究报道了开腹肝切除术的安全性。在此,我们报告了首例为冯-威廉氏病(VWD)患者实施腹腔镜肝切除术的病例:病例介绍:一名 76 岁的男性患者,有慢性丙型肝炎和 VWD 2B 型病史,医生建议他对肝脏第 7 节段的 4 厘米肝细胞癌进行手术切除。患者在 40 岁时因胃溃疡引起消化道出血而被诊断为 VWD。冯-威廉因子(VWF)里斯托西汀辅助因子活性为 30%,观察到 VWF 大多聚体缺乏和里斯托西汀诱导的血小板凝集增加。术前血小板计数降至 3.5 × 104/μL;然而,术前影像学检查结果没有肝硬化的证据,如任何侧支形成和脾肿大。15 分钟时吲哚菁绿保留率为 10%,Child-Pugh 评分为 5(A 级)。围手术期,按照本机构的方案使用了 VWF/因子 VIII。腹腔镜下进行了右后段肝部分切除术。由于腹膜后和肿瘤之间的炎症粘连,手术中最多的出血发生在肝脏右叶的移动过程中。实质横切时的出血是可以控制的。肝血流闭塞时间为65分钟。手术时间为 349 分钟,估计失血量为 2150 毫升。在实质横断开始时输注了 4 个单位的红细胞和新鲜冰冻血浆,在实质横断结束时输注了 10 个单位的血小板。术后第 1 天,横断面表面引流液出现出血,急诊对比增强计算机断层扫描显示大网膜有外渗。对右侧胃网膜动脉分支进行了经皮经导管动脉栓塞术。术后无需进一步干预。患者于术后第14天出院:结论:VWD患者腹腔镜肝切除术的适应症应慎重考虑,开腹手术可能仍是VWD患者的标准方法。
{"title":"Laparoscopic liver resection for a patient of hepatocellular carcinoma with von Willebrand disease: a case report.","authors":"Oğuzhan Şal, Katsunori Sakamoto, Kei Tamura, Masahiko Honjo, Yusuke Nishi, Naotake Funamizu, Kohei Ogawa, Yasutsugu Takada","doi":"10.1186/s40792-024-01960-4","DOIUrl":"10.1186/s40792-024-01960-4","url":null,"abstract":"<p><strong>Background: </strong>The safety of laparoscopic hepatectomy for inherited coagulation disorders is unclear; however, the safety of open hepatectomy has been reported in several studies. Herein, we report the first case of a laparoscopic hepatectomy for a patient with von Willebrand Disease (VWD).</p><p><strong>Case presentation: </strong>A 76-year-old male with a history of chronic hepatitis C and VWD type 2B was advised surgical resection of a 4 cm hepatocellular carcinoma in segment 7 of the liver. The patient was diagnosed with VWD in his 40 s due to gastrointestinal bleeding caused by gastric erosion. The von Willebrand factor (VWF) ristocetin cofactor activity was 30%, and VWF large multimer deficiency and increased ristocetin-induced platelet agglutination were observed. The preoperative platelet count was reduced to 3.5 × 10<sup>4</sup>/μL; however, preoperative imaging findings had no evidence of liver cirrhosis, such as any collateral formations and splenomegaly. The indocyanine green retention rate at 15 min was 10%, and his Child-Pugh score was 5 (classification A). Perioperatively, VWF/factor VIII was administered in accordance with our institutional protocol. A laparoscopic partial hepatectomy of the right posterior segment was performed. The most bleeding during surgery occurred during the mobilization of the right lobe of the liver due to inflammatory adhesion between the retroperitoneum and the tumor. Bleeding during parenchymal transection was controlable. The duration of hepatic inflow occlusion was 65 min. The surgical duration was 349 min, and the estimated blood loss was 2150 ml. Four units of red blood cells and fresh frozen plasma were transfused at the initiation of parenchymal transection, and 10 units of platelets were transfused at the end of the parenchymal transection. On postoperative day 1, the transection surface drainage fluid became hemorrhagic, and emergency contrast-enhanced computed tomography showed extravasation in the greater omentum. Percutaneous transcatheter arterial embolization of the omental branch of the right gastroepiploic artery was performed. No further postoperative interventions were required. The patient was discharged on postoperative day 14.</p><p><strong>Conclusion: </strong>The indications for laparoscopic hepatectomy in patients with VWD should be carefully considered, and an open approach may still be the standard approach for patients with VWD.</p>","PeriodicalId":22096,"journal":{"name":"Surgical Case Reports","volume":null,"pages":null},"PeriodicalIF":0.7,"publicationDate":"2024-06-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11208378/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141459409","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Correction: Laparoscopic repair of a primary parahiatal hernia combined with gastric volvulus: a case report and literature review. 更正:原发性腹股沟旁疝合并胃扩张的腹腔镜修补术:病例报告和文献综述。
IF 0.7 Q4 SURGERY Pub Date : 2024-06-26 DOI: 10.1186/s40792-024-01952-4
Hirotada Muramatsu, Hisashi Amaike, Rena Ogura, Kouichi Shirono, Noriyuki Kamiya
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引用次数: 0
A case of chronic expanding hematoma mimicking a cystic pancreatic tumor. 一例模仿胰腺囊性肿瘤的慢性膨胀性血肿。
IF 0.7 Q4 SURGERY Pub Date : 2024-06-26 DOI: 10.1186/s40792-024-01957-z
Asuna Sakamoto, Yasuhisa Ando, Dongping Feng, Mina Nagao, Hiroyuki Matsukawa, Bunpei Nishiura, Akihiro Kondo, Hironobu Suto, Eisuke Asano, Takayoshi Kishino, Minoru Oshima, Kensuke Kumamoto, Keiichi Okano

Background: A chronic expanding hematoma is an uncommon entity described as an organized blood collection that increases in size after the initial hemorrhagic event without histological neoplastic features. The standard treatment is complete resection. To our knowledge, this is the first report of a chronic expanding hematoma mimicking a pancreatic cystic tumor that has been successfully resected utilizing a laparoscopic approach.

Case presentation: We report the case of a 32-year-old man with a 10-cm chronic expanding hematoma that was preoperatively diagnosed as a cystic pancreatic tumor. Dynamic computed tomography revealed a cyst at the inferior part of the uncinate process of the pancreas without contrast enhancement. His blood biochemical data were within normal limits. The operation initially utilized a laparoscopic approach; however, the procedure was converted to hand-assisted laparoscopic surgery due to capsule adherence to surrounding organs and finally, enucleation of the tumor was performed. Pathological findings revealed a chronic expanding hematoma in the retroperitoneal space.

Conclusion: Chronic expanding hematoma in the retroperitoneal space is so rare and sometimes adheres to the surrounding tissue. It is difficult to distinguish hematoma attaching pancreas and pancreatic cyst preoperatively. In rare cases such as this, hand-assisted laparoscopic surgery is a feasible, less invasive procedure for facilitating complete resection and preventing recurrence.

背景:慢性膨胀性血肿是一种不常见的疾病,它是一种有组织的血液聚集,在最初的出血事件后体积增大,但无组织学肿瘤特征。标准治疗方法是完全切除。据我们所知,这是第一例模仿胰腺囊性肿瘤的慢性膨胀性血肿,并利用腹腔镜方法成功切除的病例报告:我们报告了一名32岁男性的病例,他患有10厘米的慢性膨胀性血肿,术前诊断为胰腺囊性肿瘤。动态计算机断层扫描显示,胰腺钩突下段有一个囊肿,但无造影剂增强。他的血液生化数据在正常范围内。手术最初采用腹腔镜方法,但由于囊肿与周围器官粘连,手术改为手辅助腹腔镜手术,最后进行了肿瘤去核。病理结果显示,腹膜后间隙有慢性扩张性血肿:结论:腹膜后间隙慢性膨胀性血肿非常罕见,有时会与周围组织粘连。术前很难区分附着在胰腺上的血肿和胰腺囊肿。在这种罕见病例中,手辅助腹腔镜手术是一种可行的微创手术,有利于彻底切除和预防复发。
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引用次数: 0
Surgical treatment of appendiceal mucormycosis in an immunocompromised patient: a case report. 一名免疫力低下患者阑尾粘液瘤病的手术治疗:病例报告。
IF 0.7 Q4 SURGERY Pub Date : 2024-06-25 DOI: 10.1186/s40792-024-01958-y
Yukiya Orihara, Shingo Kurahashi, Katsuhiko Kamei, Kazuhiro Hiramatsu

Background: Gastrointestinal mucormycosis is a rapidly progressing and often fatal disease, predominantly affecting immunocompromised patients. Surgical intervention, in addition to antifungal therapy, is essential. Herein, we describe the successful management of appendiceal mucormycosis in a patient with acute promyelocytic leukemia through rapid surgical intervention and antifungal therapy.

Case presentation: A 29-year-old woman underwent autologous peripheral blood stem cell transplantation for acute promyelocytic leukemia (APL). Subsequently, her condition relapsed, and remission induction therapy was initiated. During the immunosuppressive period, she developed a fever and severe abdominal pain. Computed tomography revealed severe edema of the ileum, cecum, and ascending colon. Despite receiving multiple antibiotics, antivirals, and antifungals, her condition showed no improvement. Consequently, she underwent exploratory laparotomy, with no bowel perforation noted, revealing severe inflammation in the ileum, cecum, and ascending colon, as well as appendiceal necrosis. Appendectomy was performed, and histopathological analysis revealed hyphae in the vessels and layers of the appendiceal wall, suggestive of mucormycosis. The patient was diagnosed with appendiceal mucormycosis, and liposomal amphotericin B was administered. Subsequent monitoring showed no recurrence of mucormycosis. Genetic analysis of the resected tissue revealed Rhizopus microspores as the causative agent.

Conclusions: Rapid surgical intervention and antifungal drug administration proved successful in managing appendiceal mucormycosis in a patient with APL. Early recognition and aggressive surgical intervention are imperative to improve outcomes in such patients.

背景:胃肠道粘孢子菌病是一种进展迅速、往往致命的疾病,主要影响免疫力低下的患者。除了抗真菌治疗外,手术干预也是必不可少的。在此,我们描述了一名急性早幼粒细胞白血病患者通过快速手术干预和抗真菌治疗成功治愈阑尾粘液瘤病的病例:一名 29 岁的女性因急性早幼粒细胞白血病(APL)接受了自体外周血干细胞移植。随后,她的病情复发,并开始接受缓解诱导治疗。在免疫抑制期间,她出现了发烧和剧烈腹痛。计算机断层扫描显示回肠、盲肠和升结肠严重水肿。尽管她接受了多种抗生素、抗病毒药物和抗真菌药物治疗,但病情仍不见好转。因此,她接受了探查性开腹手术,在没有发现肠穿孔的情况下,发现回肠、盲肠和升结肠有严重炎症,阑尾也出现坏死。对患者进行了阑尾切除术,组织病理学分析显示,阑尾壁的血管和各层均有菌丝,提示为粘孢子菌病。患者被诊断为阑尾粘液瘤病,并服用了两性霉素 B 脂质体。随后的监测显示,粘液瘤病没有复发。对切除组织的基因分析显示,小孢子根霉菌是致病菌:事实证明,快速手术干预和抗真菌药物治疗成功地控制了一名 APL 患者的阑尾粘液瘤病。要改善此类患者的预后,早期识别和积极手术干预势在必行。
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引用次数: 0
A case of successful management for spontaneous rupture of paraganglioma treated with preoperative transcatheter arterial embolization. 一例术前经导管动脉栓塞治疗副神经节瘤自发性破裂的成功病例。
IF 0.7 Pub Date : 2024-06-21 DOI: 10.1186/s40792-024-01907-9
Masataka Nakagawa, Naoki Tanimine, Hiroshi Sakai, Ryosuke Nakano, Shintaro Kuroda, Masahiro Ohira, Hiroyuki Tahara, Kentaro Ide, Tsuyoshi Kobayashi, Kouji Arihiro, Hideki Ohdan

Background: Tumors arising from catecholamine-producing chromophil cells in paraganglia are termed paragangliomas (PGLs), which biologically resemble pheochromocytomas (PCCs) that arise from the adrenal glands. Spontaneous rupture of a PGL is rare and can be fatal. Although elective surgery for ruptured PCCs after transcatheter arterial embolization (TAE) has been shown to provide good outcomes, the efficacy of TAE pretreatment for ruptured PGL remains unknown.

Case presentation: A 65-year-old female with hypertension and tachycardia was diagnosed with a 3-cm PGL located behind the inferior vena cava. The patient was scheduled to undergo an elective surgery with antihypertensive therapy. However, she presented with a chief complaint of abdominal pain and was diagnosed with intratumoral hemorrhage. Urgent TAE was performed that successfully achieved hemorrhage control. After TAE, serum levels of both epinephrine and norepinephrine were within the normal range. Abdominal computed tomography revealed resolving retroperitoneal hematoma. Elective open surgery was performed without significant intraoperative bleeding or fluctuations in blood pressure.

Conclusion: We report a case of successful preoperative TAE for functional PGL to control intraoperative blood pressure fluctuations and bleeding. Preoperative TAE could be a useful procedure for the surgical preparation of functional PGL, including unruptured cases.

背景:副神经节内产生儿茶酚胺的嗜铬细胞所产生的肿瘤被称为副神经节瘤(PGL),其生物学特征类似于肾上腺产生的嗜铬细胞瘤(PCC)。副神经节瘤的自发性破裂非常罕见,而且可能致命。虽然经导管动脉栓塞术(TAE)后对破裂的PCC进行择期手术可获得良好的疗效,但对破裂的PGL进行TAE预处理的疗效仍不清楚:一名 65 岁女性,患有高血压和心动过速,被诊断出患有位于下腔静脉后方的 3 厘米 PGL。患者原计划在降压治疗的同时接受择期手术。然而,她出现了腹痛的主诉,并被诊断为瘤内出血。医生紧急为她进行了TAE手术,成功控制了出血。TAE 后,血清中的肾上腺素和去甲肾上腺素水平均在正常范围内。腹部计算机断层扫描显示腹膜后血肿已消退。择期开腹手术顺利完成,术中无明显出血或血压波动:我们报告了一例成功的功能性PGL术前TAE,以控制术中血压波动和出血。术前 TAE 可作为功能性 PGL(包括未破裂病例)手术准备的一种有效方法。
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引用次数: 0
Intestinal obstruction secondary to perforation of Meckel's diverticulum caused by dentures: a case report and review of literature. 假牙导致梅克尔憩室穿孔继发肠梗阻:病例报告和文献综述。
IF 0.7 Pub Date : 2024-06-21 DOI: 10.1186/s40792-024-01959-x
Gaoyuan Tian, Zefeng Yuan, Ming Luo, Yujin Zhang, Bin Kong

Background: Meckel's diverticulum (MD) is the most common congenital abnormality of the gastrointestinal tract. However, MD is rare in clinical practice, and perforation of a MD by a foreign body is even rarer. Preoperative diagnosis is difficult because there is often insufficient information; therefore it is usually diagnosed intraoperatively. Although rare, it should be considered as a differential diagnosis in patients who have ingested foreign bodies.

Case presentation: The following is the case of a 52-year-old female patient who was admitted because of generalized abdominal pain for 5 days, related to nausea and vomiting. She also stopped passing gas. Inflammatory indicators were elevated, and computed tomography (CT) revealed gas-liquid levels in the small intestine and high-density objects in the ileum. Based on the patient's condition, laparotomy was performed instead because the laparoscopic procedure was difficult to perform. Intraoperatively, a foreign body perforated the diverticulum of the terminal ileum, resulting in the development of an abdominal abscess. Finally, we performed resection of the ileal diverticula and partial resection of the ileum. After the surgery, it was confirmed that the foreign bodies were two dentures accidentally eaten by the patient.

Conclusion: A thorough understanding of the clinical presentation, imaging features, and treatment of MD and its complications will assist clinicians in making prompt and accurate diagnoses and providing symptomatic treatment.

背景:梅克尔憩室(MD)是胃肠道最常见的先天性畸形。然而,梅克尔憩室在临床上并不多见,而异物穿孔则更为罕见。术前诊断很困难,因为往往没有足够的信息,因此通常在术中进行诊断。虽然罕见,但应将其作为误食异物患者的鉴别诊断:以下是一名 52 岁女性患者的病例,她因全身腹痛 5 天,伴有恶心和呕吐而入院。她还停止排气。炎症指标升高,计算机断层扫描(CT)显示小肠内有气液水平,回肠内有高密度物体。根据患者的情况,由于腹腔镜手术难以实施,因此改为开腹手术。术中,异物穿破了回肠末端的憩室,导致腹腔脓肿。最后,我们进行了回肠憩室切除术和回肠部分切除术。术后证实,异物是患者误食的两颗假牙:全面了解 MD 及其并发症的临床表现、影像学特征和治疗方法将有助于临床医生做出及时、准确的诊断并提供对症治疗。
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Surgical Case Reports
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