Pub Date : 2024-01-02DOI: 10.1186/s43162-023-00266-5
Amira M. Elsayed, Mohamad S. Elsayed, Ahmed E. Mansour, A. Mahedy, Eman M. Araby, Maha H. Morsy, Rasha O. Abd Elmoniem
{"title":"Predictors of COVID-19 outcome in type 2 diabetes mellitus: a hospital-based study","authors":"Amira M. Elsayed, Mohamad S. Elsayed, Ahmed E. Mansour, A. Mahedy, Eman M. Araby, Maha H. Morsy, Rasha O. Abd Elmoniem","doi":"10.1186/s43162-023-00266-5","DOIUrl":"https://doi.org/10.1186/s43162-023-00266-5","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"2 8","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139389930","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Correlation between neutrophil to lymphocyte ratio and platelet to lymphocyte ratio with proteinuria in different stages of chronic kidney disease","authors":"Fathima Azra Aneez, Nifla Shariffdeen, Fathima Asra Haleem, Brammah R Thangarajah, Karunaithas Rasaratnam","doi":"10.1186/s43162-023-00270-9","DOIUrl":"https://doi.org/10.1186/s43162-023-00270-9","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"123 47","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1186/s43162-023-00272-7
A. Bouchaala, J. Nguadi, N. Mouine, H. Bouzelmat, A. Benyass
{"title":"Sinus arrest associated with diabetic ketoacidosis regressing to sinus rhythm after compensation of diabetic process: a case report and review of literature","authors":"A. Bouchaala, J. Nguadi, N. Mouine, H. Bouzelmat, A. Benyass","doi":"10.1186/s43162-023-00272-7","DOIUrl":"https://doi.org/10.1186/s43162-023-00272-7","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"114 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139391149","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-01-02DOI: 10.1186/s43162-023-00267-4
Arnab Purkayastha, A. Kalwar, Zakia Firdaus, Bhaskar Kanti Nath, P. Bhattacharjee
{"title":"Platelet to lymphocyte ratio: can it be an early economical mortality predictor of AKI patients?","authors":"Arnab Purkayastha, A. Kalwar, Zakia Firdaus, Bhaskar Kanti Nath, P. Bhattacharjee","doi":"10.1186/s43162-023-00267-4","DOIUrl":"https://doi.org/10.1186/s43162-023-00267-4","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"73 14","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139390090","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-12DOI: 10.1186/s43162-023-00265-6
Mahmoud Nassar, Aelia Jaffery, Bassel Ibrahim, B. Baraka, H. Abosheaishaa
{"title":"The multidimensional benefits of eicosapentaenoic acid: from heart health to inflammatory control","authors":"Mahmoud Nassar, Aelia Jaffery, Bassel Ibrahim, B. Baraka, H. Abosheaishaa","doi":"10.1186/s43162-023-00265-6","DOIUrl":"https://doi.org/10.1186/s43162-023-00265-6","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"7 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139009687","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-12-01DOI: 10.1186/s43162-023-00264-7
S. Hosny, M. Nasr, Moataz M. W. Abd Elfattah, Samar Helmy Abdel Dayem, Rana Hashem Ibrahim
{"title":"Correction: Evaluating the relation between serum apolipoprotein B (apo B), apolipoprotein A (apo A) and apo B/apo A ratio with diabetic retinopathy in a sample of type 2 Egyptian diabetic patient","authors":"S. Hosny, M. Nasr, Moataz M. W. Abd Elfattah, Samar Helmy Abdel Dayem, Rana Hashem Ibrahim","doi":"10.1186/s43162-023-00264-7","DOIUrl":"https://doi.org/10.1186/s43162-023-00264-7","url":null,"abstract":"","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":" 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138618512","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-10DOI: 10.1186/s43162-023-00263-8
Rizk Sayad R. Sarhan, Yasmin M. Marei, Yomna M. Marei
Abstract Objectives Evaluation of the ability of estimated levels of fecal calprotectin (FCP), serum intelectin-1 (ITLN1), and C-reactive protein (CRP) to differentiate between patients with ulcerative colitis (UC) and irritable bowel syndrome (IBS). Patients Three-hundred forty-two patients were evaluated clinically for diagnostic criteria of UC and IBD and underwent colonoscopic examination and grading according to Mayo endoscopic scores (MES). Colorectal biopsies were taken for microscopic examination. Fecal and blood samples were obtained for ELISA estimation of levels of the studied variate. Patients were grouped according to microscopic examination of the obtained biopsies as UC and IBD groups. Study outcome is the ability of the laboratory variate for prediction of the microscopic diagnosis. Results In UC patients, FCP and serum CRP levels were notably elevated compared to controls and IBS patients. Conversely, UC patients exhibited significantly reduced serum ITLN1 levels in comparison to controls and IBS patients with insignificantly lower levels in samples of IBS patients. Statistical analyses defined high FCP and low serum ITLN1 as the significant predictors for UC diagnosis with high specificity for FCP level > 150 µg/ml and high sensitivity for serum ITLN1 ≤ 30 and ≤ 18 ng/ml to predict colonoscopic and microscopic UC diagnosis, respectively. Conclusion The combination of high FCP and low serum ITLN1 could accurately predict the colonoscopic and microscopic findings of UC and can differentiate UC from IBS and may spare the need for colonoscopy and biopsy especially for IBS patients.
{"title":"Evaluation of the diagnostic performance of estimated fecal calprotectin and serum intelectin-1 and C-reactive protein solo or in combination for differentiation between patients with query ulcerative colitis and irritable bowel syndrome","authors":"Rizk Sayad R. Sarhan, Yasmin M. Marei, Yomna M. Marei","doi":"10.1186/s43162-023-00263-8","DOIUrl":"https://doi.org/10.1186/s43162-023-00263-8","url":null,"abstract":"Abstract Objectives Evaluation of the ability of estimated levels of fecal calprotectin (FCP), serum intelectin-1 (ITLN1), and C-reactive protein (CRP) to differentiate between patients with ulcerative colitis (UC) and irritable bowel syndrome (IBS). Patients Three-hundred forty-two patients were evaluated clinically for diagnostic criteria of UC and IBD and underwent colonoscopic examination and grading according to Mayo endoscopic scores (MES). Colorectal biopsies were taken for microscopic examination. Fecal and blood samples were obtained for ELISA estimation of levels of the studied variate. Patients were grouped according to microscopic examination of the obtained biopsies as UC and IBD groups. Study outcome is the ability of the laboratory variate for prediction of the microscopic diagnosis. Results In UC patients, FCP and serum CRP levels were notably elevated compared to controls and IBS patients. Conversely, UC patients exhibited significantly reduced serum ITLN1 levels in comparison to controls and IBS patients with insignificantly lower levels in samples of IBS patients. Statistical analyses defined high FCP and low serum ITLN1 as the significant predictors for UC diagnosis with high specificity for FCP level > 150 µg/ml and high sensitivity for serum ITLN1 ≤ 30 and ≤ 18 ng/ml to predict colonoscopic and microscopic UC diagnosis, respectively. Conclusion The combination of high FCP and low serum ITLN1 could accurately predict the colonoscopic and microscopic findings of UC and can differentiate UC from IBS and may spare the need for colonoscopy and biopsy especially for IBS patients.","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"108 37","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135137104","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-08DOI: 10.1186/s43162-023-00259-4
S. Basma, A. Al-Hajje, P. Salameh, I. Nader, AM. Henaine
Abstract Background Chronic obstructive pulmonary disease (COPD) is currently one of the leading causes of death worldwide, with 90% of these deaths reported in low- and middle-income countries. In Lebanon, the prevalence of COPD is 9.7%. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends the use of antibiotics and corticosteroids in inpatients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The studies examining the level of conformity with the GOLD recommendations are rare, which increases the need for the current study. Methods A 3-month cross-sectional study was done. Patients included were those diagnosed with acute exacerbations of COPD and admitted to one of the selected hospitals in Beirut, of various nationalities and sexes, aged 18 to 89. Data were selected from patient files admitted between January 2020 and June 2022 using a data collection sheet. The SPSS version 24 statistics software was used to conduct statistical analysis. Results A total of 260 patients were recruited, with 86.7% receiving systemic corticosteroids, 24.3% respecting dose, and 81.8% respecting the appropriate duration of corticosteroid intake. 80% exhibited pulmonary indications for receiving antibiotics, and 56.53% had the necessary cardinal symptoms. Around 74.5% of patients use antibiotics for the recommended time of 5 to 7 days. Age ( p value = 0.006), gender ( p value = 0.049), alcohol consumption ( p value = 0.018), and use of psychiatric medications ( p value = 0.049) are correlated with the conformity index of corticosteroid administration. A correlation was observed between the duration of use of antibiotics with cardinal symptoms ( p value = 0.003), CRP-value ( p value = 0.007), and type of hospital ( p value = 0.00). Conclusion This investigation revealed a need for correction in a deviation from the guidelines, shed light on existing clinical procedures, and emphasized the growing concern about the uncontrollable rate of antibiotic use and inadequate corticosteroid dosing.
{"title":"Corticosteroid and antibiotic use in hospitalized patients in Lebanon with acute exacerbation of chronic obstructive pulmonary disease","authors":"S. Basma, A. Al-Hajje, P. Salameh, I. Nader, AM. Henaine","doi":"10.1186/s43162-023-00259-4","DOIUrl":"https://doi.org/10.1186/s43162-023-00259-4","url":null,"abstract":"Abstract Background Chronic obstructive pulmonary disease (COPD) is currently one of the leading causes of death worldwide, with 90% of these deaths reported in low- and middle-income countries. In Lebanon, the prevalence of COPD is 9.7%. The Global Initiative for Chronic Obstructive Lung Disease (GOLD) recommends the use of antibiotics and corticosteroids in inpatients with acute exacerbation of chronic obstructive pulmonary disease (AECOPD). The studies examining the level of conformity with the GOLD recommendations are rare, which increases the need for the current study. Methods A 3-month cross-sectional study was done. Patients included were those diagnosed with acute exacerbations of COPD and admitted to one of the selected hospitals in Beirut, of various nationalities and sexes, aged 18 to 89. Data were selected from patient files admitted between January 2020 and June 2022 using a data collection sheet. The SPSS version 24 statistics software was used to conduct statistical analysis. Results A total of 260 patients were recruited, with 86.7% receiving systemic corticosteroids, 24.3% respecting dose, and 81.8% respecting the appropriate duration of corticosteroid intake. 80% exhibited pulmonary indications for receiving antibiotics, and 56.53% had the necessary cardinal symptoms. Around 74.5% of patients use antibiotics for the recommended time of 5 to 7 days. Age ( p value = 0.006), gender ( p value = 0.049), alcohol consumption ( p value = 0.018), and use of psychiatric medications ( p value = 0.049) are correlated with the conformity index of corticosteroid administration. A correlation was observed between the duration of use of antibiotics with cardinal symptoms ( p value = 0.003), CRP-value ( p value = 0.007), and type of hospital ( p value = 0.00). Conclusion This investigation revealed a need for correction in a deviation from the guidelines, shed light on existing clinical procedures, and emphasized the growing concern about the uncontrollable rate of antibiotic use and inadequate corticosteroid dosing.","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"47 S1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135342356","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-08DOI: 10.1186/s43162-023-00261-w
Aniruddha Jog, Vinayak M. Sawardekar, Arjun Agarwal
Abstract Background Meningoencephalitis and herpes zoster ophthalmicus (HZO) are rare neurological and ocular complications of herpes zoster, respectively. Their co-occurrence is rarer, even in patients with retroviral disease (RVD), and may occur in the presence of normal CD4 count. Case presentation A 35-year-old woman presented with altered sensorium. Four days back, she developed left-sided severe, deep burning type headache, and on the next day, painful vesicles developed over the left side of the scalp which progressively involved the forehead, upper part of left cheek, and tip of the nose, with swelling around the eyes. Ophthalmic examination revealed conjunctivitis and keratitis suggesting acute HZO. Neck rigidity was present, and MRI brain was suggestive of acute meningoencephalitis. The DNA polymerase chain reaction of cerebrospinal fluid for varicella zoster virus (VZV) confirmed the diagnosis of acute meningoencephalitis. The search for cause of immunosuppression led to the diagnosis of RVD. Treatment with intravenous acyclovir and dexamethasone led to rapid recovery and clearing of lesions. Conclusion VZV infection should be included in the differential diagnosis among patients with newly diagnosed RVD presenting with meningoencephalitis and HZO.
{"title":"Herpes zoster ophthalmicus and varicella zoster meningoencephalitis in a newly diagnosed case of retroviral disease: a case report","authors":"Aniruddha Jog, Vinayak M. Sawardekar, Arjun Agarwal","doi":"10.1186/s43162-023-00261-w","DOIUrl":"https://doi.org/10.1186/s43162-023-00261-w","url":null,"abstract":"Abstract Background Meningoencephalitis and herpes zoster ophthalmicus (HZO) are rare neurological and ocular complications of herpes zoster, respectively. Their co-occurrence is rarer, even in patients with retroviral disease (RVD), and may occur in the presence of normal CD4 count. Case presentation A 35-year-old woman presented with altered sensorium. Four days back, she developed left-sided severe, deep burning type headache, and on the next day, painful vesicles developed over the left side of the scalp which progressively involved the forehead, upper part of left cheek, and tip of the nose, with swelling around the eyes. Ophthalmic examination revealed conjunctivitis and keratitis suggesting acute HZO. Neck rigidity was present, and MRI brain was suggestive of acute meningoencephalitis. The DNA polymerase chain reaction of cerebrospinal fluid for varicella zoster virus (VZV) confirmed the diagnosis of acute meningoencephalitis. The search for cause of immunosuppression led to the diagnosis of RVD. Treatment with intravenous acyclovir and dexamethasone led to rapid recovery and clearing of lesions. Conclusion VZV infection should be included in the differential diagnosis among patients with newly diagnosed RVD presenting with meningoencephalitis and HZO.","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"106 5","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-08","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135342399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-11-06DOI: 10.1186/s43162-023-00262-9
Ahmed Suparno Bahar Moni, Tiffany Ann Johnson, Cade Ray McGarvey, Razia Sultana Ivy, Tasmia Jahan Yean, Muhamad Zabidi Ahmad
Abstract A definitive diagnosis of soft tissue cystic swelling is challenging, as clinical and imaging findings might misguide the clinician and delay timely diagnosis and treatment as well as outcome. The radiological features of tubercular cysts often overlap with that of sarcoma or metastatic cancer. Involvement of a multidisciplinary team, tissue biopsy, and histopathology should supplement standard diagnostic testing and imaging to confirm the diagnosis and avoid delay in treatment. We report a case of multiple cystic swelling of the upper limb, ankle, and pelvis mimicking metastatic ovarian cancer which was later diagnosed as a case of disseminated tuberculosis.
{"title":"Diagnostic dilemma in disseminated TB could be fatal: lesson learned through a bitter encounter","authors":"Ahmed Suparno Bahar Moni, Tiffany Ann Johnson, Cade Ray McGarvey, Razia Sultana Ivy, Tasmia Jahan Yean, Muhamad Zabidi Ahmad","doi":"10.1186/s43162-023-00262-9","DOIUrl":"https://doi.org/10.1186/s43162-023-00262-9","url":null,"abstract":"Abstract A definitive diagnosis of soft tissue cystic swelling is challenging, as clinical and imaging findings might misguide the clinician and delay timely diagnosis and treatment as well as outcome. The radiological features of tubercular cysts often overlap with that of sarcoma or metastatic cancer. Involvement of a multidisciplinary team, tissue biopsy, and histopathology should supplement standard diagnostic testing and imaging to confirm the diagnosis and avoid delay in treatment. We report a case of multiple cystic swelling of the upper limb, ankle, and pelvis mimicking metastatic ovarian cancer which was later diagnosed as a case of disseminated tuberculosis.","PeriodicalId":22465,"journal":{"name":"The Egyptian Journal of Internal Medicine","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-11-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135634806","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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