Pub Date : 2023-01-01DOI: 10.2530/jslsm.jslsm-44_0023
T. Ikeda, H. Matsui
{"title":"Combined Endoscopic Techniques for Esophageal Pinhole-like Stenosis after Photodynamic Therapy","authors":"T. Ikeda, H. Matsui","doi":"10.2530/jslsm.jslsm-44_0023","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-44_0023","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"65 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74511932","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-01-01DOI: 10.2530/jslsm.jslsm-44_0004
Akinari Bando, Kazunori Watanabe, Takashi Ohtsuki
{"title":"Photochemical internalizationに基づく光依存的細胞質内RNA導入法の副作用低減","authors":"Akinari Bando, Kazunori Watanabe, Takashi Ohtsuki","doi":"10.2530/jslsm.jslsm-44_0004","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-44_0004","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"90060408","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-15DOI: 10.2530/jslsm.jslsm-43_0021
章 青木
{"title":"「歯と歯髄領域におけるレーザー・LED応用の特色ある研究」の特集によせて","authors":"章 青木","doi":"10.2530/jslsm.jslsm-43_0021","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-43_0021","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-07-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88203866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-04-15DOI: 10.2530/jslsm.jslsm-43_0006
実男 臼田
{"title":"「呼吸器領域におけるレーザー医療の進歩と課題」の特集によせて","authors":"実男 臼田","doi":"10.2530/jslsm.jslsm-43_0006","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-43_0006","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"161 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-04-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"77949031","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-15DOI: 10.2530/jslsm.jslsm-42_0031
{"title":"第33回日本レーザー医学会西日本大会（旧：関西支部会）","authors":"","doi":"10.2530/jslsm.jslsm-42_0031","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-42_0031","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"33 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"91201042","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-15DOI: 10.2530/jslsm.jslsm-42_0030
{"title":"The 43th Annual Meeting of Japan Society for Laser Surgery and Medicine","authors":"","doi":"10.2530/jslsm.jslsm-42_0030","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-42_0030","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"26 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88217737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-15DOI: 10.2530/jslsm.jslsm-42_0032
{"title":"第33回日本レーザー治療学会 総会・学術大会開催のご案内","authors":"","doi":"10.2530/jslsm.jslsm-42_0032","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-42_0032","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"138 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80743064","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-15DOI: 10.2530/jslsm.jslsm-42_0033
{"title":"第32回日本光線力学学会学術講演会 第18回日本脳神経外科光線力学学会 合同学術講演会","authors":"","doi":"10.2530/jslsm.jslsm-42_0033","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-42_0033","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"85962101","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-15DOI: 10.2530/jslsm.jslsm-42_0028
秀雄 福原, 圭紀 森田
{"title":"「次世代AI画像認識」の特集によせて","authors":"秀雄 福原, 圭紀 森田","doi":"10.2530/jslsm.jslsm-42_0028","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-42_0028","url":null,"abstract":"","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"21 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74161954","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-01-01DOI: 10.2530/jslsm.jslsm-43_0020
J. Akimoto, T. Takura
The aim of the present study was to perform a comparative evaluation of the cost-effectiveness of health insurance-approved additional treatments to the standard Stupp regimen for newly diagnosed glioblastoma. According to the clinical symptoms and disease progression of patients with newly diagnosed glioblastoma, a Markov model was constructed to estimate the quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs). Utility parameters were obtained from the data of published phase II or III clinical studies. Additional intraoperative treatment using carmustine wafers and photodynamic therapy (PDT) increased overall costs by 1,035,000 yen and 1,212,290 yen, with a gain in 0.221 and 0.552 QALYs, resulting in ICERs of 4,683,258 yen/QALY and 2,196,178 yen/QALY, respectively. Furthermore, additional postoperative adjuvant treatment using Bevacizumab and Tumor-treating field increased overall costs by 4,719,942 yen and 9,000,000 yen, with a gain in 0.14 and 0.257 QALYs, resulting in ICERs of 33,713,971 yen/QALY and 35,019,455 yen/QALY, respectively. These data suggested that the additional intraoperative PDT was the most cost-effective treatment for patients with newly diagnosed glioblastoma in the context of an ICER of 5,000,000 yen/QALY willingness-to-pay threshold. The main limitation of this study was that the additional costs required for the adverse events that may occur as a result of these treatments were not evaluated, and these should be evaluated in the future using real-world diagnosis procedure combination (DPC) data. In summary, we showed that additional intraoperative PDT is an extremely low-cost and high-quality treatment option for the patients with newly diagnosed glioblastoma, using medico-economical evaluation.
{"title":"The Cost-Effectiveness Evaluation of the Intraoperative Additional Photodynamic Therapy for the Treatment of Newly Diagnosed Glioblastoma","authors":"J. Akimoto, T. Takura","doi":"10.2530/jslsm.jslsm-43_0020","DOIUrl":"https://doi.org/10.2530/jslsm.jslsm-43_0020","url":null,"abstract":"The aim of the present study was to perform a comparative evaluation of the cost-effectiveness of health insurance-approved additional treatments to the standard Stupp regimen for newly diagnosed glioblastoma. According to the clinical symptoms and disease progression of patients with newly diagnosed glioblastoma, a Markov model was constructed to estimate the quality-adjusted life years (QALYs) and incremental cost-effectiveness ratios (ICERs). Utility parameters were obtained from the data of published phase II or III clinical studies. Additional intraoperative treatment using carmustine wafers and photodynamic therapy (PDT) increased overall costs by 1,035,000 yen and 1,212,290 yen, with a gain in 0.221 and 0.552 QALYs, resulting in ICERs of 4,683,258 yen/QALY and 2,196,178 yen/QALY, respectively. Furthermore, additional postoperative adjuvant treatment using Bevacizumab and Tumor-treating field increased overall costs by 4,719,942 yen and 9,000,000 yen, with a gain in 0.14 and 0.257 QALYs, resulting in ICERs of 33,713,971 yen/QALY and 35,019,455 yen/QALY, respectively. These data suggested that the additional intraoperative PDT was the most cost-effective treatment for patients with newly diagnosed glioblastoma in the context of an ICER of 5,000,000 yen/QALY willingness-to-pay threshold. The main limitation of this study was that the additional costs required for the adverse events that may occur as a result of these treatments were not evaluated, and these should be evaluated in the future using real-world diagnosis procedure combination (DPC) data. In summary, we showed that additional intraoperative PDT is an extremely low-cost and high-quality treatment option for the patients with newly diagnosed glioblastoma, using medico-economical evaluation.","PeriodicalId":22716,"journal":{"name":"The Journal of Japan Society for Laser Surgery and Medicine","volume":"196 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"72568154","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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