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The journal of pain : official journal of the American Pain Society最新文献

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Change in "Self-as-Context" ("Perspective-Taking") Occurs in Acceptance and Commitment Therapy for People With Chronic Pain and Is Associated With Improved Functioning. 在慢性疼痛患者的接受和承诺治疗中,“自我情境”(“换位思考”)发生了变化,并与功能改善有关。
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2017.01.005
Lin Yu, S. Norton, L. McCracken
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引用次数: 68
Mild Social Stress in Mice Produces Opioid-Mediated Analgesia in Visceral but Not Somatic Pain States. 小鼠轻度社会应激在内脏而非躯体疼痛状态下产生阿片介导的镇痛。
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2017.02.422
M. Pitcher, R. González-Cano, Kathleen Vincent, M. Lehmann, E. J. Cobos, T. Coderre, J. Baeyens, F. Cerveró
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引用次数: 12
Modest Amounts of Voluntary Exercise Reduce Pain- and Stress-Related Outcomes in a Rat Model of Persistent Hind Limb Inflammation. 在大鼠后肢持续性炎症模型中,适量的自愿运动可减少疼痛和压力相关的结果。
Pub Date : 2017-06-01 Epub Date: 2017-02-07 DOI: 10.1016/j.jpain.2017.01.006
Mark H Pitcher, Farid Tarum, Imran Z Rauf, Lucie A Low, Catherine Bushnell

Aerobic exercise improves outcomes in a variety of chronic health conditions, yet the support for exercise-induced effects on chronic pain in humans is mixed. Although many rodent studies have examined the effects of exercise on persistent hypersensitivity, the most used forced exercise paradigms that are known to be highly stressful. Because stress can also produce analgesic effects, we studied how voluntary exercise, known to reduce stress in healthy subjects, alters hypersensitivity, stress, and swelling in a rat model of persistent hind paw inflammation. Our data indicate that voluntary exercise rapidly and effectively reduces hypersensitivity as well as stress-related outcomes without altering swelling. Moreover, the level of exercise is unrelated to the analgesic and stress-reducing effects, suggesting that even modest amounts of exercise may impart significant benefit in persistent inflammatory pain states.

Perspective: Modest levels of voluntary exercise reduce pain- and stress-related outcomes in a rat model of persistent inflammatory pain, independently of the amount of exercise. As such, consistent, self-regulated activity levels may be more relevant to health improvement in persistent pain states than standardized exercise goals.

有氧运动改善了各种慢性健康状况的结果,但对运动诱导的对人类慢性疼痛的影响的支持是混合的。尽管许多啮齿类动物研究已经检查了运动对持续性超敏反应的影响,但最常用的强迫运动模式是已知的高压力。由于压力也可以产生镇痛作用,我们研究了在健康受试者中可以减轻压力的自愿运动如何改变持续后肢炎症大鼠模型中的超敏反应、压力和肿胀。我们的数据表明,自愿运动可以快速有效地减少过敏和压力相关的结果,而不会改变肿胀。此外,运动水平与镇痛和减压效果无关,这表明即使是适度的运动也可能对持续的炎症性疼痛状态有显著的好处。观点:适度的自愿运动可以减轻持续炎症性疼痛大鼠模型的疼痛和压力相关结果,与运动量无关。因此,与标准化的运动目标相比,持续的、自我调节的活动水平可能与持续疼痛状态下的健康改善更相关。
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引用次数: 0
The Value of Prognostic Screening for Patients With Low Back Pain in Secondary Care. 腰痛患者预后筛查在二级护理中的价值。
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2016.12.020
E. L. Karran, A. Traeger, James H. McAuley, Susan L. Hillier, Y. Yau, G. L. Moseley
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引用次数: 31
Preschool Needle Pain Responding: Establishing 'Normal'. 学龄前针痛反应:建立“正常”。
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2017.01.010
Jordana A. Waxman, Miranda G. DiLorenzo, R. P. Pillai Riddell, D. Flora, S. Greenberg, H. Garfield
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引用次数: 10
Safety, Pharmacokinetics, and Pharmacodynamics Study in Healthy Subjects of Oral NEO6860, a Modality Selective Transient Receptor Potential Vanilloid Subtype 1 Antagonist. 健康受试者口服一种形态选择性瞬时受体电位拮抗剂NEO6860的安全性、药代动力学和药效学研究
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2017.01.009
W. Brown, R. Leff, A. Griffin, S. Hossack, Roxane Aubray, P. Walker, D. Chiche
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引用次数: 38
Trajectory of Improvement in Children and Adolescents With Chronic Migraine: Results From the Cognitive-Behavioral Therapy and Amitriptyline Trial. 儿童和青少年慢性偏头痛的改善轨迹:来自认知行为疗法和阿米替林试验的结果。
Pub Date : 2017-06-01 DOI: 10.1016/j.jpain.2017.01.002
J. Kroner, J. Peugh, S. Kashikar-Zuck, S. LeCates, Janelle R. Allen, S. Slater, M. Zafar, M. Kabbouche, Hope L. O’Brien, Chad E. Shenk, Ashley M. Kroon Van Diest, A. Hershey, S. Powers
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引用次数: 24
AAPT Diagnostic Criteria for Chronic Sickle Cell Disease Pain. 慢性镰状细胞病疼痛的AAPT诊断标准。
Pub Date : 2017-05-01 DOI: 10.1016/j.jpain.2016.12.016
C. Dampier, T. Palermo, D. Darbari, K. Hassell, Wally R. Smith, W. Zempsky
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引用次数: 137
Seeing an Embodied Virtual Hand is Analgesic Contingent on Colocation. 虚拟手的视觉效果取决于位置。
Pub Date : 2017-01-17 DOI: 10.1016/j.jpain.2017.01.003
B. Nierula, M. Martini, Marta Matamala-Gomez, M. Slater, Maria V. Sanchez-Vives
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引用次数: 64
Inhibition of Reinforcing, Hyperalgesic, and Motor Effects of Morphine by Buspirone in Rats. 丁螺环酮对大鼠吗啡强化、痛觉过敏和运动效应的抑制作用。
Pub Date : 2017-01-01 DOI: 10.1016/j.jpain.2016.10.001
D. Haleem, Shazia Nawaz
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引用次数: 25
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The journal of pain : official journal of the American Pain Society
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