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Cardiovascular PKC activation and gap junctional abnormality in diabetic state 糖尿病状态下心血管PKC激活与间隙连接异常
Pub Date : 2000-01-01 DOI: 10.5551/jat1973.27.9-10_273
F. Umeda, T. Kuroki, T. Inoguchi
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引用次数: 0
Paraoxonase (PON1) and polymorphisms of PON1 gene 对氧磷酶(PON1)及其基因多态性
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.4-5_105
Tadashi Sueiro, Toshihiro Nakamura, M. Inoue, Y. Kumon, K. Hashimoto
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引用次数: 0
Gene diagnosis of hypertension 高血压的基因诊断
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.4-5_111
J. Higaki, T. Katsuya, K. Ishikawa, T. Ogihara
{"title":"Gene diagnosis of hypertension","authors":"J. Higaki, T. Katsuya, K. Ishikawa, T. Ogihara","doi":"10.5551/JAT1973.27.4-5_111","DOIUrl":"https://doi.org/10.5551/JAT1973.27.4-5_111","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81860206","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Coagulation and Fibrinolysis in Atherosclerosis 动脉粥样硬化中的凝血和纤溶
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.11_283
U. Ikeda, Y. Hojo, K. Kario, H. Funayama, K. Shimada
急性冠症候群の発症機序 においては, 冠動脈壁のプラー クが破裂 し, その内容物が血中に暴露 されることによる血 栓の形成が重要であることが示されている1,2). また, 剖検 例などの検討から, プラーク破裂の組織学的な特徴が検討 され, 破裂 しやすいプラークの特徴 としては, 単球 ・マク ロファージなどの炎症細胞浸潤が強いことが明らかにされ ている3,4). すなわち, 単球の内皮細胞への接着, 内皮下へ の浸潤は, 動脈硬化の初期病変の形成, さらにはその終末 像であるプラークの破綻に重要な役割を果たしている5). 血管内皮細胞は, 生理的な状況下では凝固 ・線溶系や血 小板などと相互に作用し, 血管の抗血栓性を維持 してい る. 一方, 病的状況下, すなわち炎症や感染などでは一時 的に向血栓性が上昇する. そこで, 単球 と内皮細胞のイン ターアクションの急性冠症候群への関わ りについて, 凝 固・線溶の面から検討した6). 方法としては, 内皮細胞はヒ ト臍 帯 静脈 よ り, 単 球 は末 梢 血 よ り分 離 し, 内皮 細 胞 と単
在急性冠状动脉综合征的发病机制中,冠状动脉壁的普勒破裂,其内容物暴露于血中而形成血栓是很重要的。1,2)另外,根据剖检例等的研究,研究了斑块破裂的组织学特征,作为容易破裂的斑块的特征,明确了单核细胞、膜噬菌体等的炎症细胞浸润强。单核细胞与内皮细胞的粘附、内皮下的浸润,对动脉硬化的早期病变的形成,乃至作为其终末象的斑块的破裂起着重要作用5).血管内皮细胞在生理状况下与凝血、线溶系统和血小板等相互作用,维持血管的抗血栓性。另一方面,在病态状况下,即炎症和感染等情况下,血栓性会暂时上升。因此,关于单核细胞和内皮细胞的inthaction与急性冠脉综合征的关系,从凝固、线溶方面进行了研究6).方法是内皮细胞与脐带静脉分离,单核细胞与末梢血分离,与内皮细胞分离
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引用次数: 0
Transcriptional Regulation of Lipid Metabolism in vivo by SREBP Family SREBP家族对体内脂质代谢的转录调控
Pub Date : 2000-01-01 DOI: 10.5551/jat1973.27.12_299
H. Shimano
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引用次数: 0
Mechanisms of growth and migration of vascular smooth muscle cells and their roles in atherogenesis 血管平滑肌细胞的生长和迁移机制及其在动脉粥样硬化中的作用
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.4-5_117
S. Mori, Y. Saito
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引用次数: 0
Mutations and variants in the human lipoprotein lipase gene 人脂蛋白脂肪酶基因的突变和变异
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.4-5_99
T. Gotoda
{"title":"Mutations and variants in the human lipoprotein lipase gene","authors":"T. Gotoda","doi":"10.5551/JAT1973.27.4-5_99","DOIUrl":"https://doi.org/10.5551/JAT1973.27.4-5_99","url":null,"abstract":"","PeriodicalId":22769,"journal":{"name":"The journal of Japan Atherosclerosis Society","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2000-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"79634811","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Infectious Pathogens in human vascular diseases: are they etiological agents or ubiquitous bystanders?@@@―感染寄生体は病原因子となりうるか?― Infectious Pathogens in human vascular diseases:are they etiological agents or ubiquitous bystanders?感染的寄生体能成为病原因子吗?-
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.6_179
Y. Yonemitsu, K. Sueishi
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引用次数: 0
Molecular genetic study and its clinical application of low-density lipoprotein receptor and apolipoprotein B-100 低密度脂蛋白受体和载脂蛋白B-100的分子遗传学研究及其临床应用
Pub Date : 2000-01-01 DOI: 10.5551/JAT1973.27.4-5_93
K. Kajinami
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引用次数: 0
血管機能測定-大動脈脈波速度,頸動脈のStiffness parameterβを用いた非侵襲的動脈硬化度診断- 血管机能测定-大动脉脉波速度,颈动脉のStiffness parameterβを用いた非侵袭的动脉硬化度诊断-
Pub Date : 1999-10-20 DOI: 10.5551/JAT1973.26.11-12_321
藤代 健太郎, 大山 俊郎, 鈴木 賢二
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引用次数: 0
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The journal of Japan Atherosclerosis Society
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