Pub Date : 2023-09-15DOI: 10.7704/kjhugr.2023.0041
Byeong Yun Ahn, Soo-Jeong Cho
The escalating prevalence of clarithromycin resistance in cases of Helicobacter pylori, insufficient acid suppression, and pharmacodynamic variations secondary to inter-individual differences in CYP2C19 polymorphism collectively contribute to suboptimal eradication rates observed with proton pump inhibitor (PPI)-based therapy. Compared with PPIs, potassium-competitive acid blockers (PCABs) produce rapid, potent, and long-lasting suppression of gastric acid through reversible inhibition of gastric H+, K+-ATPase. PCAB-based therapy results in significant inhibition of acid secretion and has therefore emerged as a novel and effective approach for H. pylori eradication. In this study, we review the efficacy and safety profile of PCAB-based eradication regimens comprising vonoprazan, tegoprazan, and fexuprazan.
{"title":"Potassium-competitive Acid Blockers: A New Therapeutic Strategy for Helicobacter pylori Eradication","authors":"Byeong Yun Ahn, Soo-Jeong Cho","doi":"10.7704/kjhugr.2023.0041","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0041","url":null,"abstract":"The escalating prevalence of clarithromycin resistance in cases of Helicobacter pylori, insufficient acid suppression, and pharmacodynamic variations secondary to inter-individual differences in CYP2C19 polymorphism collectively contribute to suboptimal eradication rates observed with proton pump inhibitor (PPI)-based therapy. Compared with PPIs, potassium-competitive acid blockers (PCABs) produce rapid, potent, and long-lasting suppression of gastric acid through reversible inhibition of gastric H+, K+-ATPase. PCAB-based therapy results in significant inhibition of acid secretion and has therefore emerged as a novel and effective approach for H. pylori eradication. In this study, we review the efficacy and safety profile of PCAB-based eradication regimens comprising vonoprazan, tegoprazan, and fexuprazan.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"44854572","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-15DOI: 10.7704/kjhugr.2023.0036
Byeong Yun Ahn, Bokyung Kim, Hyun-Chae Chung, Sang Gyun Kim, Soo-Jeong Cho
The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. IMAGE OF THE ISSUE ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0036 Korean J Helicobacter Up Gastrointest Res, 2023;23(3):222-224
{"title":"Bifurcated Lumen Observed on Capsule Endoscopy","authors":"Byeong Yun Ahn, Bokyung Kim, Hyun-Chae Chung, Sang Gyun Kim, Soo-Jeong Cho","doi":"10.7704/kjhugr.2023.0036","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0036","url":null,"abstract":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (https:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. IMAGE OF THE ISSUE ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0036 Korean J Helicobacter Up Gastrointest Res, 2023;23(3):222-224","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45609841","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-15DOI: 10.7704/kjhugr.2023.0032
Su Jin Kim
pylori
幽门
{"title":"Scratch Sign as an Endoscopic Marker for Predicting the Absence of Current Helicobacter pylori Infection","authors":"Su Jin Kim","doi":"10.7704/kjhugr.2023.0032","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0032","url":null,"abstract":"pylori","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42317611","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-09-15DOI: 10.7704/kjhugr.2023.0040
Dong Han Yeom, Yong Sung Kim
Gastric acid-related disorders are commonly encountered in clinical practice. Acetylcholine, gastrin, and histamine are physiological agonists that stimulate acid secretion from parietal cells. Histamine plays a decisive role in the transformation of parietal cells into acid-secreting forms. The H+, K+- ATPase proton pump, which represents the final step of acid secretion, translocates from cytoplasmic tubulovesicles to secretory canaliculi upon parietal cell stimulation and facilitates exchange of intracellular H+ with extracellular K+ in a 1:1 ratio. Histamine-2 receptor antagonists and proton pump inhibitors (PPIs) are widely used in clinical practice, and potassium-competitive acid blockers (P-CABs) have gained attention in recent times. P-CABs address the unmet needs of patients who receive conventional PPIs and have broadened the spectrum of drug choices; however, further research is warranted to confirm long-term safety of these drugs. Comprehensive understanding of the mechanisms of actions, characteristics, advantages and disadvantages, and the adverse effect profile is essential for appropriate prescription of gastric acid-suppressive drugs. In this review, we provide a developing history and outline the pharmacological mechanisms underlying various gastric acid-suppressive drugs used in clinical settings.
{"title":"History and Pharmacological Mechanism of Gastric Acid-suppressive Drugs","authors":"Dong Han Yeom, Yong Sung Kim","doi":"10.7704/kjhugr.2023.0040","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0040","url":null,"abstract":"Gastric acid-related disorders are commonly encountered in clinical practice. Acetylcholine, gastrin, and histamine are physiological agonists that stimulate acid secretion from parietal cells. Histamine plays a decisive role in the transformation of parietal cells into acid-secreting forms. The H+, K+- ATPase proton pump, which represents the final step of acid secretion, translocates from cytoplasmic tubulovesicles to secretory canaliculi upon parietal cell stimulation and facilitates exchange of intracellular H+ with extracellular K+ in a 1:1 ratio. Histamine-2 receptor antagonists and proton pump inhibitors (PPIs) are widely used in clinical practice, and potassium-competitive acid blockers (P-CABs) have gained attention in recent times. P-CABs address the unmet needs of patients who receive conventional PPIs and have broadened the spectrum of drug choices; however, further research is warranted to confirm long-term safety of these drugs. Comprehensive understanding of the mechanisms of actions, characteristics, advantages and disadvantages, and the adverse effect profile is essential for appropriate prescription of gastric acid-suppressive drugs. In this review, we provide a developing history and outline the pharmacological mechanisms underlying various gastric acid-suppressive drugs used in clinical settings.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-09-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42444338","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.7704/kjhugr.2023.0025
J. Seo, Kee Don Cho, I. Song, Y. S. Park, H. Na, J. Ahn, Jeong Hoon Lee, K. Jung, D. Kim, H. Song, G. Lee, H. Jung
Background/Aims: The treatment for gastric mucosa-associated lymphoid tissue lymphoma (MALToma) generally involves eradication of Helicobacter pylori . However, MALToma lesions may recur even without H. pylori re-infection. Furthermore, the remission rate of H. pylori -negative MALToma after eradication is low. Therefore, herein, we report on endoscopic submucosal dissection (ESD) as a treatment strategy for gastric MALToma. Methods: We retrospectively reviewed the data of all patients of gastric MALToma who underwent endoscopic resection at our institution between January 2000 and December 2021. Clinical remission was defined as complete histological remission or probable minimal residual disease according to the GELA grading system for post-treatment evaluation of gastric MALToma. Results: Six patients with gastric MALToma underwent ESD. Two patients were diagnosed with gastric MALToma, which improved after eradication treatment and relapsed approximately 36 and 41 months later, respectively. These patients had singular lesions localized to the mucosa and did not experience H. pylori re-infection. The lesions were successfully removed via ESD. The remaining four patients had H. pylori -negative gastric MALToma. These patients also had single, localized lesions that were removed via ESD. All the patients remained in clinical remission until the final follow-up. Conclusions: ESD is a safe and effective intervention for H. pylori -negative gastric MALToma when the lesion is single and confined to the mucosal layer. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])
{"title":"Endoscopic Submucosal Dissection for Treatment of Localized Gastric Mucosa-Associated Lymphoid Tissue Lymphoma: A Case Series","authors":"J. Seo, Kee Don Cho, I. Song, Y. S. Park, H. Na, J. Ahn, Jeong Hoon Lee, K. Jung, D. Kim, H. Song, G. Lee, H. Jung","doi":"10.7704/kjhugr.2023.0025","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0025","url":null,"abstract":"Background/Aims: The treatment for gastric mucosa-associated lymphoid tissue lymphoma (MALToma) generally involves eradication of Helicobacter pylori . However, MALToma lesions may recur even without H. pylori re-infection. Furthermore, the remission rate of H. pylori -negative MALToma after eradication is low. Therefore, herein, we report on endoscopic submucosal dissection (ESD) as a treatment strategy for gastric MALToma. Methods: We retrospectively reviewed the data of all patients of gastric MALToma who underwent endoscopic resection at our institution between January 2000 and December 2021. Clinical remission was defined as complete histological remission or probable minimal residual disease according to the GELA grading system for post-treatment evaluation of gastric MALToma. Results: Six patients with gastric MALToma underwent ESD. Two patients were diagnosed with gastric MALToma, which improved after eradication treatment and relapsed approximately 36 and 41 months later, respectively. These patients had singular lesions localized to the mucosa and did not experience H. pylori re-infection. The lesions were successfully removed via ESD. The remaining four patients had H. pylori -negative gastric MALToma. These patients also had single, localized lesions that were removed via ESD. All the patients remained in clinical remission until the final follow-up. Conclusions: ESD is a safe and effective intervention for H. pylori -negative gastric MALToma when the lesion is single and confined to the mucosal layer. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49081723","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.7704/kjhugr.2023.0026
Ji Hea Bang, Jin Hyong Kang, Seung Han Kim, Jong-Jae Park, B. Lee, M. Joo, Tae-Sung Jeon
The gastrointestinal tract is the most common extranodal site for lymphomas, and mucosa-associated lymphoid tissue lymphoma is the second most common histological lymphoma subtype. However, primary esophageal mucosa-associated lymphoid tissue lymphomas are extremely rare. Few such cases are documented, and the reports demonstrate inconsistent diagnostic and therapeutic strategies. Herein, a 54-year-old man was referred to our hospital for treatment of dysphagia. Esophagogastroduodenoscopy revealed a large, horseshoe-shaped subepithelial mass in the upper esophagus. Endoscopic ultrasonography and computed tomography revealed that the mass was well-demarcated and confined to the muscularis mucosa, with no abnormalities in other organs or lymph nodes. The mass was presumptively diagnosed as benign, and the patient underwent endoscopic mucosal dissection for pathological confirmation and symptom relief. Pathological examination of the dissection specimen revealed that it was a primary esophageal mucosa-associated lymphoid tissue lymphoma. As the patient had an elevated immunoglobulin G level and Helicobacter pylori infection, we administered adjuvant eradication therapy. The patient remains under surveillance and is free of lymphoma recurrence 36 months postoperatively. This case report demonstrates that endoscopic resection and H. pylori eradication are effective treatment strategies for early-stage esophageal mucosa-associated lymphoid tissue lymphoma. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])
{"title":"Primary Esophageal Mucosa-associated Lymphoid Tissue Lymphoma: A Rare Case Report and Review of Other Published Data","authors":"Ji Hea Bang, Jin Hyong Kang, Seung Han Kim, Jong-Jae Park, B. Lee, M. Joo, Tae-Sung Jeon","doi":"10.7704/kjhugr.2023.0026","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0026","url":null,"abstract":"The gastrointestinal tract is the most common extranodal site for lymphomas, and mucosa-associated lymphoid tissue lymphoma is the second most common histological lymphoma subtype. However, primary esophageal mucosa-associated lymphoid tissue lymphomas are extremely rare. Few such cases are documented, and the reports demonstrate inconsistent diagnostic and therapeutic strategies. Herein, a 54-year-old man was referred to our hospital for treatment of dysphagia. Esophagogastroduodenoscopy revealed a large, horseshoe-shaped subepithelial mass in the upper esophagus. Endoscopic ultrasonography and computed tomography revealed that the mass was well-demarcated and confined to the muscularis mucosa, with no abnormalities in other organs or lymph nodes. The mass was presumptively diagnosed as benign, and the patient underwent endoscopic mucosal dissection for pathological confirmation and symptom relief. Pathological examination of the dissection specimen revealed that it was a primary esophageal mucosa-associated lymphoid tissue lymphoma. As the patient had an elevated immunoglobulin G level and Helicobacter pylori infection, we administered adjuvant eradication therapy. The patient remains under surveillance and is free of lymphoma recurrence 36 months postoperatively. This case report demonstrates that endoscopic resection and H. pylori eradication are effective treatment strategies for early-stage esophageal mucosa-associated lymphoid tissue lymphoma. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"48175416","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-08-30DOI: 10.7704/kjhugr.2023.0029
J. Seo, Hyo-Jin Cho, Sang Jong Park, Ah Young Lee, Sang-Jung Kim, Ji Yong Ahn
Background/Aims: Identification of Helicobacter pylori infection status is necessary as H. pylori is associated with gastric malignancy. Recently, a red linear scrape-like appearance on the gastric mucosa, called the “scratch sign,” was reported to be associated with H. pylori -negative gastric mucosal status. Herein, we aimed to validate the association between the scratch sign and H. pylori infection status. Methods: The data of patients who underwent screening endoscopy at Bundang Jesaeng General Hospital between March 2023 and April 2023 were reviewed. Patients were classified as having an H. pylori current infection or non-infection status based on the re-sults of rapid urease tests. Patients who had undergone H. pylori eradication therapy were excluded. Endoscopic features of the gastric mucosa were assessed using the Kyoto classification of gastritis. Results: The scratch sign appeared more frequently in patients with non-infection than in those with current infection status (32.7% vs. 10.6%, respectively; P <0.001). Multivariate analysis showed that only the presence of sticky mucus was significantly associated with the presence of the scratch sign. Patient without the scratch sign had a higher prevalence of open-type atrophy, intestinal meta-plasia, enlarged folds, and diffuse redness, which reflected a higher Kyoto score. Conclusions: Presence of the gastric mucosal scratch sign, a novel endoscopic marker, is indicative of H. pylori -negative status and appears to be inversely correlated with the presence of sticky mucus. In addition to the Kyoto classification of gastritis, detection of the scratch sign may facilitate identification of the H. pylori infection status. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])
{"title":"Validation of a Novel Endoscopic Feature that Predicts Helicobacter pylori-negative Status: Does the Scratch Sign Reflect H. pylori Non-infection?","authors":"J. Seo, Hyo-Jin Cho, Sang Jong Park, Ah Young Lee, Sang-Jung Kim, Ji Yong Ahn","doi":"10.7704/kjhugr.2023.0029","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0029","url":null,"abstract":"Background/Aims: Identification of Helicobacter pylori infection status is necessary as H. pylori is associated with gastric malignancy. Recently, a red linear scrape-like appearance on the gastric mucosa, called the “scratch sign,” was reported to be associated with H. pylori -negative gastric mucosal status. Herein, we aimed to validate the association between the scratch sign and H. pylori infection status. Methods: The data of patients who underwent screening endoscopy at Bundang Jesaeng General Hospital between March 2023 and April 2023 were reviewed. Patients were classified as having an H. pylori current infection or non-infection status based on the re-sults of rapid urease tests. Patients who had undergone H. pylori eradication therapy were excluded. Endoscopic features of the gastric mucosa were assessed using the Kyoto classification of gastritis. Results: The scratch sign appeared more frequently in patients with non-infection than in those with current infection status (32.7% vs. 10.6%, respectively; P <0.001). Multivariate analysis showed that only the presence of sticky mucus was significantly associated with the presence of the scratch sign. Patient without the scratch sign had a higher prevalence of open-type atrophy, intestinal meta-plasia, enlarged folds, and diffuse redness, which reflected a higher Kyoto score. Conclusions: Presence of the gastric mucosal scratch sign, a novel endoscopic marker, is indicative of H. pylori -negative status and appears to be inversely correlated with the presence of sticky mucus. In addition to the Kyoto classification of gastritis, detection of the scratch sign may facilitate identification of the H. pylori infection status. (Korean J Helicobacter Up Gastrointest Res 2023 Aug 30. [Epub ahead of print])","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-08-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45340205","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.7704/kjhugr.2023.0012
J. Oh
In 2013, the Japan Gastroenterological Endoscopy Society introduced the Kyoto classification of gastritis, which is useful to predict Helicobacter pylori infection based exclusively on endoscopic findings. Based on the Kyoto classification of gastritis, gastric mucosal atrophy, endoscopic intestinal metaplasia, hypertrophic gastric folds, nodularity, and diffuse redness may be associated with gastric cancer and H. pylori infection, which are common endoscopic findings in Koreans. Atrophy and intestinal metaplasia are associated with gastric cancer and therefore require attention. Hypertrophic gastric folds, nodularity, and diffuse redness can be associated with current H. pylori infection. The Kyoto scoring system, which is based on endoscopic findings is useful to predict current H. pylori infection and gastric cancer in the absence of biopsy evaluation in clinical settings. A therapeutic strategy for H. pylori infection based on the Kyoto score is expected to reduce the incidence of gastric cancer in Korea and Japan. In this study, we investigated the endoscopic findings commonly observed in Koreans among those defined by the Kyoto classification of gastritis.
{"title":"Endoscopic Findings of Common Gastritis in Koreans","authors":"J. Oh","doi":"10.7704/kjhugr.2023.0012","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0012","url":null,"abstract":"In 2013, the Japan Gastroenterological Endoscopy Society introduced the Kyoto classification of gastritis, which is useful to predict Helicobacter pylori infection based exclusively on endoscopic findings. Based on the Kyoto classification of gastritis, gastric mucosal atrophy, endoscopic intestinal metaplasia, hypertrophic gastric folds, nodularity, and diffuse redness may be associated with gastric cancer and H. pylori infection, which are common endoscopic findings in Koreans. Atrophy and intestinal metaplasia are associated with gastric cancer and therefore require attention. Hypertrophic gastric folds, nodularity, and diffuse redness can be associated with current H. pylori infection. The Kyoto scoring system, which is based on endoscopic findings is useful to predict current H. pylori infection and gastric cancer in the absence of biopsy evaluation in clinical settings. A therapeutic strategy for H. pylori infection based on the Kyoto score is expected to reduce the incidence of gastric cancer in Korea and Japan. In this study, we investigated the endoscopic findings commonly observed in Koreans among those defined by the Kyoto classification of gastritis.","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"49569778","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.7704/kjhugr.2023.0028
Kyung Ho Song
The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. EDITORIAL ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0028 The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023;23(2):79-80
{"title":"Bismuth, An Indispensable Component of Helicobacter pylori Eradication Therapy","authors":"Kyung Ho Song","doi":"10.7704/kjhugr.2023.0028","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0028","url":null,"abstract":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. EDITORIAL ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0028 The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023;23(2):79-80","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45341332","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-06-15DOI: 10.7704/kjhugr.2023.0027
Y. Kwon
The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. EDITORIAL ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0027 The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023;23(2):81-83
{"title":"Evidence-based Therapy: A Rational Approach to Helicobacter pylori Eradication","authors":"Y. Kwon","doi":"10.7704/kjhugr.2023.0027","DOIUrl":"https://doi.org/10.7704/kjhugr.2023.0027","url":null,"abstract":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research is an Open-Access Journal. All articles are distributed under the terms of the Creative Commons Attribution Non-Commercial License (http:// creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. EDITORIAL ISSN 1738-3331 eISSN 2671-826X, https://doi.org/10.7704/kjhugr.2023.0027 The Korean Journal of Helicobacter and Upper Gastrointestinal Research, 2023;23(2):81-83","PeriodicalId":22895,"journal":{"name":"The Korean Journal of Helicobacter and Upper Gastrointestinal Research","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"46666779","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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