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Acute Cholecystitis Presenting as a Subcutaneous Abscess and Sepsis 急性胆囊炎表现为皮下脓肿和败血症
Pub Date : 2019-02-25 DOI: 10.21885/wvmj.2019.6
E. Thompson, Gilberto A. Garza, Jacob D Miller
A 67-year-old female presented with vague abdominal pain, renal failure, and sepsis. A CT scan without contrast was obtained and subcutaneous fluid was seen along with a large calcified gallstone. After antibiotics, fluid resuscitation and dialysis, the patient was taken to the operating room where a large subcutaneous abscess was found. The abdominal wall was debrided and an open cholecystectomy was attempted. Because of dense adhesions and inflammation, a cholecystostomy tube was placed. The patient required a skin graft after her abdominal wall debridement. Her gallbladder was removed 4 months later. This patient presented with a rare complication of acute cholecystitis - gallbladder rupture into the subcutaneous tissues. In this manuscript, we discuss this case and the literature.
67岁女性,腹痛不清,肾功能衰竭,败血症。CT扫描未做对比,可见皮下积液伴一大块钙化胆结石。经抗生素、液体复苏和透析后,患者被送往手术室,发现一个大的皮下脓肿。腹壁清创并尝试开腹胆囊切除术。由于紧密粘连和炎症,我们放置了胆囊造瘘管。病人在腹壁清创后需要植皮。4个月后切除了胆囊。这个病人出现了一个罕见的急性胆囊炎并发症-胆囊破裂进入皮下组织。在本文中,我们讨论了这个案例和文献。
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引用次数: 0
Fiberoptic Nasotracheal Intubation in the Emergency Department for Severe Upper Airway Obstruction 纤维鼻气管插管在急诊科治疗严重上呼吸道阻塞中的应用
Pub Date : 2019-02-20 DOI: 10.21885/WVMJ.2019.4
Msiv Joseph Watson, Kristen M. Craig, Tanya Fancy, Daniel Merenda, C. Whiteman, Mph Melinda J. Sharon
Angioedema of the upper airway can pose a challenge in emergency airway management. The semi-awake fiberoptic nasotracheal intubation is an uncommonly performed procedure that allows for the establishment of a definitive airway without removing the patient’s airway reflexes, protecting against the cannot intubate-cannot oxygenate scenario. Although common teaching in emergency medicine training, fiberoptic nasotracheal intubations are rarely performed. We report a case of a successful intubation in a patient with an acute upper airway obstruction later found due to angioedema. Emergency physicians should have routine training and access to fiberoptic equipment to provide optimal patient care.
上呼吸道血管性水肿是急诊气道管理的一个挑战。半清醒纤维鼻气管插管是一种罕见的手术,它允许在不消除患者气道反射的情况下建立明确的气道,防止无法插管-无法充氧的情况。虽然在急诊医学培训中常见,但纤维鼻气管插管很少进行。我们报告一例插管成功的病人急性上呼吸道阻塞后来发现由于血管性水肿。急诊医生应接受常规培训并使用光纤设备,以提供最佳的病人护理。
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引用次数: 0
An Atypical Presentation of Apathetic Thyrotoxicosis Requiring Thyroidectomy In The Acute Setting 急性情况下需要甲状腺切除术的失活性甲状腺毒症的不典型表现
Pub Date : 2019-02-05 DOI: 10.21885/WVMJ.2019.2
M. Koh, Md Mph Facs Melissa LoPinto
Apathetic thyrotoxicosis is an atypical manifestation of thyrotoxicosis characterized by depression, lethargy, and weakness.1 Patients are often elderly and have no known history of hyperthyroidism. Typical symptoms of hyperthyroidism such as hyperkinetic motor activity and exophthalmos are often absent. In the classical description, apathetic thyrotoxicosis is a distinct clinical entity, however the end stage presentation of typical thyrotoxicosis may result in apathy with considerable overlap in clinical features. This unique case illustrates a scenario in which untreated typical thyrotoxicosis progressed to an apathetic state, thus suggesting that apathetic thyrotoxicosis and end stage untreated thyrotoxicosis may be variations of the same disease process rather than distinct clinical entities. Here we present a 53 year old woman with typical Graves’ disease, treated initially with methimazole. She developed methimazole-induced agranulocytosis, requiring cessation of treatment. After a period of inadequate treatment, she represented in a clinically apathetic state, with biochemically uncontrolled hyperthyroidism. Following emergent medical stabilization, she successfully underwent definitive total thyroidectomy.
淡化型甲状腺毒症是甲状腺毒症的一种不典型表现,其特点是抑郁、嗜睡和虚弱患者多为老年人,无甲亢病史。甲状腺机能亢进的典型症状,如运动亢进和眼球突出往往不存在。在经典的描述中,冷漠性甲状腺毒症是一个独特的临床实体,然而,典型甲状腺毒症的终末期表现可能导致冷漠,在临床特征上有相当大的重叠。这个独特的病例说明了一个未经治疗的典型甲状腺毒症进展到冷漠状态的情况,因此表明冷漠期甲状腺毒症和终末期未经治疗的甲状腺毒症可能是同一疾病过程的变化,而不是不同的临床实体。在这里我们提出一个53岁的妇女与典型的格雷夫斯病,最初用甲巯咪唑治疗。她出现甲巯咪唑诱导的粒细胞缺乏症,需要停止治疗。经过一段时间的不适当治疗后,她表现为临床麻木状态,伴有生化不受控制的甲状腺功能亢进。在紧急医疗稳定后,她成功地接受了甲状腺全切除术。
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引用次数: 1
Chlamydia trachomatis Associated Fitz-Hugh-Curtis Syndrome 沙眼衣原体相关菲兹-休-柯蒂斯综合征
Pub Date : 2019-01-30 DOI: 10.21885/wvmj.2019.1
Msiii Alexander C. Schlarb, A. S. Martin, Timothy A. VanHoose, R. Zagoria
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引用次数: 0
Pulmonary Involvement in Sjögren’s Syndrome: Lymphocytic Interstitial Pneumonia Transforming into Lymphoma Sjögren综合征肺部受累:淋巴细胞间质性肺炎转化为淋巴瘤
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.8
Rahul Sangani, MD, Lana Winkler, MD, Zalak Patel, MD
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引用次数: 0
A five-year follow up of doctors treating relatives and themselves 对治疗亲属和自己的医生进行了为期五年的跟踪调查
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.14
Jasmyn E. Atalla, BS, Ross D. DeChant, MD, Lynne J. Goebel, MD, FACP, Corresponding Author: Maurice A. Mufuson, MD, MACP
Studies show high rates of physicians believing that they should treat relatives and themselves In this study, we compared such attitudes in surveys conducted in 2017 and 2012 among similar populations of physicians who attended Internal Medicine, Pediatrics, Family Medicine, and OB/ GYN Grand Rounds. Fewer respondents in 2017 prescribed medications to relatives without an examination. Similar numbers of residents and faculty in both years believed they should treat their relatives. Fifty-nine percent treated relatives for minor illnesses, a significant decrease from 75.3% in 2012. About half of physicians treated themselves for minor illnesses in both years. Although 73% of current respondents had a primary care physician (PCP), a significantly higher proportion of men had PCPs (p-0.04) in 2017 in contrast to a significantly higher proportion of women in 2012 (p=0.01). The overall frequency of residents and faculty physicians who treat relatives and themselves decreased in the past five years and less treat without examination. However, too many physicians continue this practice, despite the ethical admonitions of the AMA and ACP. More education is required to convince physicians not to treat relatives and themselves. Further research is needed to determine why men now have PCPs more often than women.
在这项研究中,我们比较了2017年和2012年对参加内科、儿科、家庭医学和妇产科大查房的类似人群的医生进行的调查中的这种态度。2017年,未经检查就给亲属开处方药的受访者减少了。在这两年中,有相当数量的住院医生和教师认为他们应该治疗自己的亲属。为家属治疗小病的比例从2012年的75.3%大幅下降至59%。在这两年中,大约有一半的医生自己治疗小病。尽管73%的受访者拥有初级保健医生(PCP),但2017年男性拥有初级保健医生的比例(p-0.04)明显高于2012年女性的比例(p=0.01)。住院医师和院系医师治疗亲属和自己的总体频率在过去五年中有所下降,不进行检查的治疗也越来越少。然而,太多的医生不顾AMA和ACP的道德警告,继续这种做法。需要更多的教育来说服医生不要治疗亲属和自己。需要进一步的研究来确定为什么现在男性比女性更常患pcp。
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引用次数: 0
Concussions in High School Sports in the Eastern Panhandle of West Virginia 2008-2017 2008-2017年西弗吉尼亚州东部狭长地带高中体育中的脑震荡
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.12
Michael J. Niemann, Ryan Sprouse, MD, CAQSM, George D. Harris, MD, MS, CAQSM, Nathan T. Fiore
The incidence and prevalence of sport-related concussion has increased over the past decade as a result of an increase in athletic participation, improved diagnostic methods, and an overall increased awareness of the symptoms and signs of concussions. This is a retrospective study identifying high school athletes in the Eastern Panhandle of West Virginia who participated in baseline and post-concussion neurocognitive ImPACT testing from 2008-2017. A total of p40 unique first post injury tests were performed, and a total of 9,850 unique baseline tests were perlormed. The athletes were baseline tested at the beginning of their freshman and junior years. New students and any student who had had a concussion in the previous year were tested prior to starting, their respective sport season. The number of post-concussion tests was compared to the number of baseline tests and stratified each year by age, sex, and sport. Comparing our findings with the incidence by sport reported in the medical literature demonstrated that the same sports identified as being the highest and lowest risk were generally congruent with the sports reported to be the highest and lowest risk in two large literature reviews » B. The notable exception was cheerleading; our study found it to be among the sports with a higher incidence of concussion. A review of the literature demonstrated that cheerleaders, like participants in other contact sports, are at significant risk for concussion. Previously concussion rates in cheerleading bad been reported to be relatively low (4- 6% of cheerleading injuries) compared to other injuries and compared to concussion rates in other sports. However, concussions were noted to be the most common cheerleading injury, accounting for 31.1% of injuries. " and also reported that the number and rate of cheerleading related concussions had increased by 290% from 2001 to 2012.
在过去十年中,由于运动参与的增加、诊断方法的改进以及对脑震荡症状和体征的总体认识的提高,运动相关脑震荡的发病率和流行率有所增加。这是一项回顾性研究,研究对象是西弗吉尼亚州东部狭长地带的高中运动员,他们在2008年至2017年期间参加了基线和脑震荡后神经认知影响测试。总共进行了p40次独特的首次损伤后试验,总共进行了9,850次独特的基线试验。这些运动员在大一和大三开始时接受了基线测试。新生和任何在前一年有过脑震荡的学生在他们各自的运动赛季开始前都接受了测试。将脑震荡后测试的次数与基线测试的次数进行比较,并按年龄、性别和运动进行分层。将我们的研究结果与医学文献中报道的运动发病率进行比较,发现被确定为最高和最低风险的同一运动通常与两篇大型文献综述中报道的最高和最低风险的运动一致。我们的研究发现,它是脑震荡发生率较高的运动之一。对文献的回顾表明,啦啦队员和其他身体接触运动的参与者一样,有很大的脑震荡风险。据报道,与其他伤害和其他运动的脑震荡率相比,啦啦队运动中的脑震荡率相对较低(啦啦队受伤的4- 6%)。然而,脑震荡被认为是最常见的啦啦队伤害,占伤害的31.1%。他们还报道说,从2001年到2012年,与啦啦队有关的脑震荡的数量和发生率增加了290%。
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引用次数: 0
Painful Hemorrhagic Lesion of Right Palm 右手掌疼痛性出血性病变
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.13
Lauryn Falcone, PhD, Omid Jalali, MD, Corresponding Author: Roxann Powers, MD
Herpes simplex virus (HSV) infections are ubiquitous in the population in the more than half of all people seropositive HSV-2. While these in cause oral or genital lesions, anywhere on the body Herpetic whitlow class painful swollen, vesicular lesion of the digits due to HSV infection. In some instances, however, the skin lesion of HSV may appear atypical. In the following report, we describe a unique case of a hemorrhagic, pustular appearing herpetic whitlow infection of the hand. This report serves to remind physicians to consider the diagnosis of HV for a painful skin lesion of the hand, as herpetic whitlow can mimic more serious conditions and early detection can limit the spread of the disease.
单纯疱疹病毒(HSV)感染在人群中普遍存在,半数以上的人血清中HSV-2呈阳性。而这些在引起口腔或生殖器病变,身体任何部位疱疹whitlow类疼痛肿胀,由于HSV感染的水泡性病变。然而,在某些情况下,HSV的皮肤病变可能表现为非典型。在以下的报告中,我们描述了一个独特的病例出血,脓疱出现疱疹whitlow感染的手。本报告提醒医生考虑对手部疼痛皮肤损伤的HV诊断,因为疱疹whitlow可以模拟更严重的疾病,早期发现可以限制疾病的传播。
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引用次数: 0
Delays in care of sudden sensorineural hearing loss, an unrecognized emergency 对突发性感音神经性听力损失的护理延误,这是一种未被识别的紧急情况
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.3
Scott Shapiro, MD, Brian Wiseman, BS, Brian Kellermeyer, MD, Michele Carr, MD, DMD, PhD, Stephen Wetmore MD, MBA, Adam Cassis, MD
Sudden sensorineural hearing loss (SSNHL) is an acute loss of hearing due to poorly understood insults to the inner ear. SSNHL is a medical emergency warranting urgent referral to an otolaryngology specialist because hearing outcomes are improved with steroid treatment that must be administered soon after the onset of hearing loss to be effective, making early diagnosis and triage essential to salvaging hearing. This prospective study catalogued the timeline of the onset of hearing loss, diagnosis, treatment, and settings where care was administered for patients with SSNHL. We diagnosed 21 patients with SSNHL in the otolaryngology specialty clinics of West Virginia University over a 6 month time period. Nine of those patients (42.9%) were diagnosed outside of the window for treatment. The most common cause of delayed diagnosis was inappropriate treatment and triage in the primary care setting, As the quality of life burden of hearing loss is quite significant, improving recognition and triage in the primary care setting would allow for more patients with SSNHL to undergo treatment, improving hearing outcomes and quality of life.
突发性感音神经性听力损失(SSNHL)是一种由于内耳损伤而引起的急性听力损失。SSNHL是一种医疗紧急情况,需要紧急转诊耳鼻喉科专家,因为听力结果可以通过类固醇治疗得到改善,而类固醇治疗必须在听力损失发生后不久进行,才能发挥作用,因此早期诊断和分诊对挽救听力至关重要。这项前瞻性研究对SSNHL患者听力损失的发病时间、诊断、治疗和护理环境进行了分类。我们在西弗吉尼亚大学耳鼻喉科专科门诊诊断了21例SSNHL患者,时间跨度为6个月。其中9名患者(42.9%)被诊断为窗外治疗。延迟诊断最常见的原因是初级保健机构的治疗和分诊不当。由于听力损失的生活质量负担相当大,改善初级保健机构的识别和分诊将使更多的SSNHL患者接受治疗,改善听力结局和生活质量。
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引用次数: 0
Sofosbuvir and Ledipasvir (Harvoni) treatment for hepatitis C in Children 索非布韦和来地帕韦(Harvoni)治疗儿童丙型肝炎
Pub Date : 2019-01-01 DOI: 10.21885/wvmj.2019.11
Yoram Elitsur, MD
bjective: Direct Acting Antiviral (DAA) drugs have been recently approved by the Food and Drug Administraation for children with HCV infection (FDA news release, April 7, 2017). We describe the first two HCV- infected children from Kentucky treated successfully with DAA drugs from a research protocol. Methods: The charts of two children with HCV infections were reviewed. Once adolescent age was achieved (12 years), both children (one naïve and one experienced) were treated for eight weeks with Sofosbuvir and Ledipasvir (Harvoni) and were monitored. Their aminotransferases and HCVRNA levels were followed before and after treatment. Results: Both children were followed for their HCV infections since infancy. Both children achieved SVR at the end of therapy, one achieved SVR 12 weeks post therapy. The second patient is still on follow up post treatment. Conclusion: This is the first report of children treated with DAA drugs not under a research protocol. We suggest the eightweek treatment may be sufficient to achieve SVR in children. Patient advocacy groups and government agencies should pressure the insurance companies to approve DAA therapy for HCVinfected children.
目的:美国食品和药物管理局(FDA)最近批准了直接作用抗病毒(DAA)药物用于HCV感染儿童(FDA新闻发布,2017年4月7日)。我们描述了来自肯塔基州的前两名HCV感染儿童成功地用研究方案中的DAA药物治疗。方法:对2例儿童HCV感染病例进行回顾性分析。一旦达到青春期(12岁),两名儿童(一名naïve和一名有经验的儿童)接受Sofosbuvir和Ledipasvir (Harvoni)治疗8周并进行监测。观察治疗前后转氨酶及HCVRNA水平。结果:两名儿童从婴儿期开始就接受了丙型肝炎病毒感染的随访。两名儿童在治疗结束时均达到SVR,其中一名在治疗后12周达到SVR。第二例患者治疗后仍在随访中。结论:这是第一个使用非研究方案的DAA药物治疗儿童的报告。我们建议8周的治疗可能足以实现儿童的SVR。患者权益团体和政府机构应该向保险公司施压,要求批准对感染丙型肝炎病毒的儿童进行DAA治疗。
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引用次数: 0
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The West Virginia medical journal
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