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Turkish Journal Of Neurology最新文献

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Investigation of stereoacuity and the relationship of with retinal nerve fiber layer thickness and P100 latency in patients with multiple sclerosis with and without optic neuritis 伴视神经炎和不伴视神经炎的多发性硬化症患者立体视敏度及其与视网膜神经纤维层厚度和P100潜伏期的关系研究
IF 0.3 Q4 Medicine Pub Date : 2022-06-15 DOI: 10.4274/tnd.2022.88555
B. Koctekin, B. Yüksel, D. Durmaz, Mert Abdullah Çilli, M. Tekindal, D. Çoban
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引用次数: 0
Evaluation of Short-Term Memory, Working Memory, and Executive Functions in Patients with Relapsing Remitting Multiple Sclerosis 评估复发缓解型多发性硬化症患者的短期记忆、工作记忆和执行功能
IF 0.3 Q4 Medicine Pub Date : 2022-06-06 DOI: 10.4274/tnd.2022.24992
Furkan Duman, Handan Can, A. Leventoğlu
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引用次数: 1
Decreased Stuttering While Walking: Speech and fMRI Findings 行走时口吃减少:言语和功能磁共振成像结果
IF 0.3 Q4 Medicine Pub Date : 2022-05-30 DOI: 10.4274/tnd.2022.40501
Özlem Öge - Daşdöğen, Çiğdem Ulaşoğlu Yıldız, E. Kurt, T. Demiralp
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引用次数: 0
The Effect of Oligoclonal Bands in Patients with Multiple Sclerosis 寡克隆条带在多发性硬化患者中的作用
IF 0.3 Q4 Medicine Pub Date : 2022-05-30 DOI: 10.4274/tnd.2022.72558
Nurhan Kaya Tutar, Elif Söylemez, Sami Ömerhoca, N. Kale Icen
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引用次数: 1
An insidious clinical picture: optic nerve involvement in COVID-19 patients 一个阴险的临床图片:COVID-19患者的视神经受累
IF 0.3 Q4 Medicine Pub Date : 2022-05-09 DOI: 10.4274/tnd.2022.67026
Özgül Ocak, E. Şahi̇n, A. Şener, Barış Ocak
Objective: Many neurological symptoms due to central nervous system, peripheral nervous system and musculoskeletal system damage have been reported in more than a third of patients with coronavirus disease-2019 (COVID-19). Although optic neuritis has been reported in patients with COVID-19, they are extremely rare. The aim of this study was screening optic nerve involvement in COVID-19 with visual evoked potential (VEP) in asymptomatic patients without a history of visual impairment. Materials and Methods: Pattern reversal VEP measurements were made in 101 adult patients with COVID-19 without a history of visual impairment after they completed COVID-19 treatments and the quarantine period. VEPs were recorded with the 4-channel electromyography-evoked device in a dark room. P100 latencies and amplitudes were analyzed by the same neurologist. Results: A total of 34 (33.7%) patients had P100 latency prolongation. There was no significant difference in terms of gender, age or outpatient/inpatient treatment status. There was no significant correlation between the time of polymerase chain reaction diagnosis and VEP values. Conclusion: Contrary to previous studies, asymptomatic optic nerve involvement after COVID-19 was detected by VEP measurements. Prolongation of P100 latency shows the probable linkage between COVID-19 virus and angiotensin converting enzyme 2 receptors in human eyes.
目的:超过三分之一的冠状病毒病-2019 (COVID-19)患者报告了由中枢神经系统、外周神经系统和肌肉骨骼系统损伤引起的许多神经系统症状。虽然在COVID-19患者中有视神经炎的报道,但它们非常罕见。本研究的目的是在无视力障碍史的无症状患者中,用视觉诱发电位(VEP)筛查视神经受累情况。材料与方法:对101例无视力障碍史的成年COVID-19患者在完成COVID-19治疗和隔离期后进行模式逆转VEP测量。用4通道肌电诱发装置在暗室中记录vep。P100潜伏期和振幅由同一位神经科医生分析。结果:34例(33.7%)患者出现P100潜伏期延长。性别、年龄、门诊/住院治疗情况无显著差异。聚合酶链反应诊断时间与VEP值无显著相关性。结论:与以往的研究相反,通过VEP测量可以检测到COVID-19后无症状视神经受累。P100潜伏期的延长表明COVID-19病毒与人眼血管紧张素转换酶2受体之间可能存在联系。
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引用次数: 0
Verbal Fluency Tests: Normative Data Stratified by Age and Education in an Istanbul Sample 语言流畅性测试:伊斯坦布尔样本中按年龄和教育分层的规范性数据
IF 0.3 Q4 Medicine Pub Date : 2022-04-12 DOI: 10.4274/tnd.2022.36824
Yasemin Sohtorik İlkmen, Ezgi Soncu Büyükişcan
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引用次数: 3
Can we predict poor outcome of Stroke Patients Without Imaging Data? A Decision Tree Analysis of Stroke Patients 我们能否在没有影像学资料的情况下预测脑卒中患者的不良预后?脑卒中患者的决策树分析
IF 0.3 Q4 Medicine Pub Date : 2022-04-12 DOI: 10.4274/tnd.2022.39024
M. Sezgin, M. G. Gunver, N. Yesilot
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引用次数: 0
Diagnostic Delay and Clinical Features In Friedreich's Ataxia 弗里德赖希共济失调的诊断延迟和临床特征
IF 0.3 Q4 Medicine Pub Date : 2022-04-05 DOI: 10.4274/tnd.2022.26780
M. Yetkin, M. Gültekin, Merve Akcakoyunlu, R. Baydemir, A. Sarılar, M. Canpolat, H. Per
{"title":"Diagnostic Delay and Clinical Features In Friedreich's Ataxia","authors":"M. Yetkin, M. Gültekin, Merve Akcakoyunlu, R. Baydemir, A. Sarılar, M. Canpolat, H. Per","doi":"10.4274/tnd.2022.26780","DOIUrl":"https://doi.org/10.4274/tnd.2022.26780","url":null,"abstract":"","PeriodicalId":23387,"journal":{"name":"Turkish Journal Of Neurology","volume":null,"pages":null},"PeriodicalIF":0.3,"publicationDate":"2022-04-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80072275","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Juvenile-onset mitochondrial-membrane protein-associated neurodegeneration with late diagnosis 青少年发病的线粒体膜蛋白相关神经变性与晚期诊断
IF 0.3 Q4 Medicine Pub Date : 2022-04-05 DOI: 10.4274/tnd.2022.26125
R. Perković, K. G. Jerčić, Manuela Frančić, D. Ozretić, F. Borovečki
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引用次数: 0
Serum leptin levels in acute ischemic stroke patients: Data from a tertiary care institution from Kashmir Valley of Northern India. 急性缺血性卒中患者血清瘦素水平:来自印度北部克什米尔山谷三级保健机构的数据。
IF 0.3 Q4 Medicine Pub Date : 2022-03-30 DOI: 10.4274/tnd.2022.33254
M. H. Bhat, Najma Kokab, J. Bhat, P. Shah
Objective: Leptin has drawn the attention of experts for its role in a myriad of conditions including stroke. However, in the absence of credible evidence linking leptin to stroke, its role as a risk factor is still debatable. We aimed to determine the leptin levels and its relationship with other cardiometabolic risk factors in patients with ischemic stroke in our region. Materials and Methods: It was a hospital based case-control observational study involving 100 patients and 100 age-and sex-matched healthy controls. Leptin levels were measured in both patients and controls in addition to estimation of lipid profile, insulin level and fasting blood glucose. Insulin resistance was calculated using the homeostasis model assessment for insulin resistance model. Carotid intima-media thickness (CIMT) was determined by high-resolution echo-colour Doppler system (GE LOGIQ S8). Neuroimaging was also performed. Student’s t-test for continuous variables, chi-square test for categorical variables and Pearson correlation coefficient to determine the correlation of leptin levels with various parameters were used. Results: The mean leptin levels were significantly higher in patients compared to control group (15.36±5.76 vs. 5.72±1.19 ng/ml; p<0.001). Leptin was found to have positive correlations with atherogenic lipid profile, inflammatory markers i.e, white blood cells and erythrocyte sedimentation rate, fasting plasma glucose and insulin resistance in patients with ischemic stroke whereas there was an inverse correlation between leptin and high density lipoproteins. Similarly leptin was found to have positive association with systolic blood pressure, body mass index and CIMT in patients. Conclusion: Hyperleptinemia is a common finding in patients with ischemic stroke and is significantly associated with various cardiovascular risk factors known to predispose to ischemic stroke.
目的:瘦素在包括中风在内的多种疾病中的作用引起了专家的注意。然而,由于缺乏将瘦素与中风联系起来的可靠证据,其作为风险因素的作用仍存在争议。我们的目的是确定瘦素水平及其与本地区缺血性卒中患者其他心脏代谢危险因素的关系。材料和方法:这是一项基于医院的病例对照观察性研究,涉及100名患者和100名年龄和性别匹配的健康对照。除了估计血脂、胰岛素水平和空腹血糖外,还测量了患者和对照组的瘦素水平。胰岛素抵抗计算采用稳态模型评估胰岛素抵抗模型。采用高分辨率回声彩色多普勒系统(GE LOGIQ S8)测定颈动脉内膜-中膜厚度(CIMT)。同时进行神经影像学检查。连续变量采用学生t检验,分类变量采用卡方检验,Pearson相关系数确定瘦素水平与各参数的相关性。结果:患者平均瘦素水平明显高于对照组(15.36±5.76∶5.72±1.19 ng/ml;p < 0.001)。研究发现,在缺血性中风患者中,瘦素与致动脉粥样硬化性脂质谱、炎症标志物(即白细胞和红细胞沉降率)、空腹血糖和胰岛素抵抗呈正相关,而瘦素与高密度脂蛋白呈负相关。同样,瘦素也被发现与患者的收缩压、体重指数和CIMT呈正相关。结论:高瘦素血症在缺血性脑卒中患者中是一种常见的发现,并且与各种已知的易患缺血性脑卒中的心血管危险因素显著相关。
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引用次数: 0
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Turkish Journal Of Neurology
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