M. Škorič, P. Fictum, V. Jekl, K. Hauptman, Z. Knotek, M. Hermanová
A 6-year-old pet female degu ( Octodon degus), in good body condition, was referred to a clinic with the presence of a large tumour in the anogenital area. The mass was bluntly dissected from the surrounding skin and muscles. The medial part of the tumour was associated with the vaginal wall which was also excised with 2 mm margins. No visible changes on the inner vaginal surface were seen. On gross examination the surface of the mass was glossy and pink-coloured; the cut surface was grey to red with greyish-white foci in a part of the mass. Histopathological examination showed a tumour composed of pleomorphic spindle to ovoid cells forming interlacing bundles and variably dense fibrous connective tissue separated by streams of neoplastic cells. Sev - eral smaller foci of coagulation necrosis were present within the tumour tissue. The neoplastic cells exhibited a high mitotic index, which ranged from six to seven mitoses per 10 high power fields. By immunohistochemical examination the positivity of neoplastic cells was demonstrated with smooth muscle actin (SMA) and vimentin, while no immunoreactivity was acquired for cytokeratins. Based on morphological features of the tumour and immunohistochemical examination a diagnosis of vaginal leiomyosarcoma was made. To our knowledge, this is the first report of a vaginal leiomyosarcoma in a degu.
{"title":"Vaginal leiomyosarcoma in a degu ( Octodon degus): a case report","authors":"M. Škorič, P. Fictum, V. Jekl, K. Hauptman, Z. Knotek, M. Hermanová","doi":"10.17221/2960-VETMED","DOIUrl":"https://doi.org/10.17221/2960-VETMED","url":null,"abstract":"A 6-year-old pet female degu ( Octodon degus), in good body condition, was referred to a clinic with the presence of a large tumour in the anogenital area. The mass was bluntly dissected from the surrounding skin and muscles. The medial part of the tumour was associated with the vaginal wall which was also excised with 2 mm margins. No visible changes on the inner vaginal surface were seen. On gross examination the surface of the mass was glossy and pink-coloured; the cut surface was grey to red with greyish-white foci in a part of the mass. Histopathological examination showed a tumour composed of pleomorphic spindle to ovoid cells forming interlacing bundles and variably dense fibrous connective tissue separated by streams of neoplastic cells. Sev - eral smaller foci of coagulation necrosis were present within the tumour tissue. The neoplastic cells exhibited a high mitotic index, which ranged from six to seven mitoses per 10 high power fields. By immunohistochemical examination the positivity of neoplastic cells was demonstrated with smooth muscle actin (SMA) and vimentin, while no immunoreactivity was acquired for cytokeratins. Based on morphological features of the tumour and immunohistochemical examination a diagnosis of vaginal leiomyosarcoma was made. To our knowledge, this is the first report of a vaginal leiomyosarcoma in a degu.","PeriodicalId":23493,"journal":{"name":"Veterinary Medicine","volume":"2003 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2018-02-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88164900","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A. Šulcová, L. Faldíková, I. Diblíková, J. Canderle, Z. Zralý
Testosterone production in mice was adversely affected by singly-housing producing either aggressive or timid social responses.
在小鼠体内产生的睾丸激素会受到单独居住产生的攻击性或胆怯的社会反应的不利影响。
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Pub Date : 1981-12-01DOI: 10.1136/jcp.34.12.1407-d
A. Gibson
The clinical features, biochemical, radiological and scan data are correlated in this atlas with alternating pages of histopathological colour plates. The sections are arranged in the fashionable problemsolving format. The colour pictures are of good quality, but neither they nor the references, which are up to date and mostly English language, are referred to in the text. Although originally published in Spanish, the quality of the English is excellent. The foreword by Fenton Schaffner suggests that the book is aimed primarily at pathologists for whom it should provide very necessary clinicopathological correlations. However, although it might achieve this to some extent, the actual histopathology is so superficial that I doubt whether many pathologists would find it useful. In particular there is virtually no discussion whatever of morphological features in differential diagnosis. Its main appeal is likely to be to postgraduates studying for higher examinations in medicine and surgery, for whom, however, it might prove rather expensive.
{"title":"Perinatal Diseases","authors":"A. Gibson","doi":"10.1136/jcp.34.12.1407-d","DOIUrl":"https://doi.org/10.1136/jcp.34.12.1407-d","url":null,"abstract":"The clinical features, biochemical, radiological and scan data are correlated in this atlas with alternating pages of histopathological colour plates. The sections are arranged in the fashionable problemsolving format. The colour pictures are of good quality, but neither they nor the references, which are up to date and mostly English language, are referred to in the text. Although originally published in Spanish, the quality of the English is excellent. The foreword by Fenton Schaffner suggests that the book is aimed primarily at pathologists for whom it should provide very necessary clinicopathological correlations. However, although it might achieve this to some extent, the actual histopathology is so superficial that I doubt whether many pathologists would find it useful. In particular there is virtually no discussion whatever of morphological features in differential diagnosis. Its main appeal is likely to be to postgraduates studying for higher examinations in medicine and surgery, for whom, however, it might prove rather expensive.","PeriodicalId":23493,"journal":{"name":"Veterinary Medicine","volume":"2 1","pages":"1830 - 1903"},"PeriodicalIF":0.0,"publicationDate":"1981-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82531557","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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