Pub Date : 2023-01-01DOI: 10.4236/wjnst.2023.134005
Jessica Lizbeth Sifuentes Padilla, David Alejandro García López, Consuelo Letechipia de León, Hector Rene Vega-Carrillo, Sergio Hugo Sánchez Rodríguez
Ionizing radiations are tools in diagnosis and treatment of diseases. Leukopenia from exposure to ionizing radiation has been reported. Due to their radiosensitivity, leukocytes are a biological model to analyze cell damage. Therefore, cell viability, DNA damage, and Hsp70 and p53 expression in human leukocytes exposed to low-dose gamma radiation fields from a 137Cs source were evaluated. A decrease in cell viability, DNA damage and an increase in the expression of Hsp70 and p53 proportional to the radiation dose received was found, which was 0.2, 0.4, 0.6, 0.8 and 1.0 mGy.
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