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A Heart Sound Classification Algorithm Based on Bispectral Analysis and Deep Learning 基于双谱分析和深度学习的心音分类算法
Chundong Xu, Zhengjie Yang, Cheng Zhu
Heart sound classification is an important research direction in the field of biomedicine, which is of great significance for reducing cardiovascular mortality. Based on the non-segmentation basis, this paper proposed to use the bispectral analysis method in the high-order spectrum for feature extraction, and then use the neural network with the attention block to perform classification learning to realize the abnormal detection of heart sound signals. The experiment used the Challenge 2016 dataset for training and testing, and finally gets a sensitivity of 0.9409, a specificity of 0.8450, and a comprehensive score of 0.8930. Compared with ResNet, MobileNet and other pre-training networks using transfer learning technology, the CNN-Attention architecture proposed in this paper has greatly reduced the number of layers. At the same time, the training time and the resources required for system operation are also drastically reduced. The performance of the proposed algorithm is generally better than the reference algorithms.
心音分类是生物医学领域的一个重要研究方向,对降低心血管病死率具有重要意义。在非分割的基础上,本文提出在高阶频谱中使用双谱分析方法进行特征提取,然后利用神经网络结合注意块进行分类学习,实现心音信号的异常检测。实验使用Challenge 2016数据集进行训练和测试,最终得到灵敏度为0.9409,特异性为0.8450,综合得分为0.8930。与ResNet、MobileNet等使用迁移学习技术的预训练网络相比,本文提出的CNN-Attention架构大大减少了层数。同时,系统运行所需的培训时间和资源也大大减少。该算法的性能总体上优于参考算法。
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引用次数: 1
Enriching Pre-Trained Language Model with Multi-Task Learning and Context for Medical Concept Normalization 基于多任务学习和语境的医学概念规范化预训练语言模型
Yiling Cao, Lu Fang, Zhongguang Zheng
Herein, we focus on the problem of automatically medical concept normalization in social media posts. Specifically, the task is to map medical mentions within social media texts to the suitable concepts in a reference knowledge base. We propose a new medical concept normalization model using multi-task learning. The model uses BioBERT to encode mentions and their contexts, and classifies their concept IDs and types of mention. We evaluate our approach on two datasets and achieve new state-of-the-art performance.
本文主要研究社交媒体帖子中医学概念的自动归一化问题。具体来说,任务是将社交媒体文本中的医学提及映射到参考知识库中的适当概念。提出了一种基于多任务学习的医学概念归一化模型。该模型使用BioBERT对提及及其上下文进行编码,并对提及的概念id和类型进行分类。我们在两个数据集上评估了我们的方法,并实现了新的最先进的性能。
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引用次数: 0
Purely Image-based Vault Prediction with Domain Prior Supervision for Intraocular Lens Implantation 人工晶状体植入术中基于领域先验监督的纯图像拱顶预测
Huihui Fang, Yifan Yang, Yu-lan Di, Zhen Qiu, Junde Wu, Mingkui Tan, Yan Luo, Yanwu Xu
Myopia is the most common eye disorder in the world, and posterior chamber phakic intraocular lens implantation, as a myopia correction surgery, has been widely used in clinics due to its reversibility, wide range of correction degree, and retention of the lens adjustment ability. We address the problem of vault prediction, which assists to ensure the safety of this myopia correction surgery. The existing methods need to measure the eye parameters first and then use the regression method, which is very time-consuming and has subjective errors. Thus, we aim to design an automatic deep learning-based method for vault prediction only considering anterior segment optical coherence tomography (AS-OCT) images. Specifically, a deep neural network is utilized to extract the image features, and then a regression module is designed to predict the vault. Furthermore, we introduce domain prior supervision into the deep learning framework. Anterior chamber structure segmentation obtained by semi-supervised learning is considered to provide additional structural features. The prediction of auxiliary measurements, which are related to the vault, is designed to deeply supervise the learning process. Experiments on our dataset (465 test samples) show that the proposed method can reduce the mean absolute error by 39.36-57.34 and 7.39-9.20 compared with the multiple regression methods and machine learning-based methods, respectively. These results show that it is promising to predict vault using AS-OCT images without parameter measurement.
近视是世界上最常见的眼部疾病,后房型人工晶状体植入术作为一种近视矫正手术,因其可逆性、矫正程度范围广、晶状体调节能力保留等优点,在临床上得到了广泛的应用。我们解决的问题,跳高预测,这有助于确保近视矫正手术的安全性。现有的方法需要先测量眼睛参数,然后再使用回归方法,这种方法非常耗时,并且存在主观误差。因此,我们的目标是设计一种仅考虑前段光学相干断层扫描(AS-OCT)图像的基于自动深度学习的拱顶预测方法。具体来说,利用深度神经网络提取图像特征,然后设计回归模块来预测金库。此外,我们将领域先验监督引入深度学习框架。通过半监督学习获得的前房结构分割被认为提供了额外的结构特征。与拱顶相关的辅助测量的预测是为了深度监督学习过程而设计的。在我们的数据集(465个测试样本)上进行的实验表明,与基于多元回归方法和基于机器学习的方法相比,本文方法的平均绝对误差分别降低了39.36-57.34和7.39-9.20。这些结果表明,利用AS-OCT图像预测拱顶是有希望的,无需参数测量。
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引用次数: 0
Named Entity Recognition in Electronic Medical Records Based on Transfer Learning 基于迁移学习的电子病历命名实体识别
Kunli Zhang, Chenghao Zhang, Yajuan Ye, Hongying Zan, Xiaomei Liu
Named entity recognition is the first step in clinical electronic medical record text mining, which is significant for clinical decision support and personalized medicine. However, the lack of annotated electronic medical record datasets limits the application of pre-trained language models and deep neural networks in this field. To alleviate the problem of data scarcity, we propose T-RoBERTa-BiLSTM-CRF, a transfer learning-based electronic medical record entity recognition model, which aggregates the characteristics of medical data from different sources and uses a small amount of electronic medical record data as target data for further training. Compared with existing models, our approach can model medical entities more effectively, and the extensive comparative experiments on the CCKS 2019 and DEMRC datasets show the effectiveness of our approach.
命名实体识别是临床电子病历文本挖掘的第一步,对临床决策支持和个性化医疗具有重要意义。然而,缺乏带注释的电子病历数据集限制了预训练语言模型和深度神经网络在该领域的应用。为了缓解数据稀缺的问题,我们提出了一种基于迁移学习的电子病历实体识别模型T-RoBERTa-BiLSTM-CRF,该模型综合了不同来源医疗数据的特征,使用少量的电子病历数据作为目标数据进行进一步训练。与现有模型相比,我们的方法可以更有效地建模医疗实体,并且在CCKS 2019和DEMRC数据集上的大量对比实验表明了我们的方法的有效性。
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引用次数: 2
ACSGRegNet: A Deep Learning-based Framework for Unsupervised Joint Affine and Diffeomorphic Registration of Lumbar Spine CT via Cross- and Self-Attention Fusion ACSGRegNet:一种基于深度学习的腰椎CT无监督关节仿射和微分同构配准框架
Xiaoru Gao, Guoyan Zheng
Registration plays an important role in medical image analysis. Deep learning-based methods have been studied for medical image registration, which leverage convolutional neural networks (CNNs) for efficiently regressing a dense deformation field from a pair of images. However, CNNs are limited in its ability to extract semantically meaningful intra- and inter-image spatial correspondences, which are of importance for accurate image registration. This study proposes a novel end-to-end deep learning-based framework for unsupervised affine and diffeomorphic deformable registration, referred as ACSGRegNet, which integrates a cross-attention module for establishing inter-image feature correspondences and a self-attention module for intra-image anatomical structures aware. Both attention modules are built on transformer encoders. The output from each attention module is respectively fed to a decoder to generate a velocity field. We further introduce a gated fusion module to fuse both velocity fields. The fused velocity field is then integrated to a dense deformation field. Extensive experiments are conducted on lumbar spine CT images. Once the model is trained, pairs of unseen lumbar vertebrae can be registered in one shot. Evaluated on 450 pairs of vertebral CT data, our method achieved an average Dice of 0.963 and an average distance error of 0.321mm, which are better than the state-of-the-art (SOTA).
配准在医学图像分析中起着重要的作用。基于深度学习的医学图像配准方法已被研究,该方法利用卷积神经网络(cnn)从一对图像中有效地回归密集变形场。然而,cnn在提取语义上有意义的图像内和图像间空间对应的能力上是有限的,而这些空间对应对于准确的图像配准至关重要。本研究提出了一种新的端到端深度学习框架,用于无监督仿射和微分同构形变配准,称为ACSGRegNet,该框架集成了用于建立图像间特征对应的交叉注意模块和用于图像内解剖结构感知的自注意模块。两个注意力模块都建立在变压器编码器上。每个注意力模块的输出分别馈送到解码器以生成速度场。我们进一步引入一个门控融合模块来融合两个速度场。然后将融合的速度场整合为密集变形场。对腰椎CT图像进行了大量的实验。一旦模型被训练,一对看不见的腰椎可以在一次拍摄中注册。对450对椎体CT数据进行评估,平均Dice为0.963,平均距离误差为0.321mm,优于目前最先进的SOTA方法。
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引用次数: 1
Proceedings of the 2022 International Conference on Intelligent Medicine and Health 2022年智能医学与健康国际会议论文集
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引用次数: 0
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Proceedings of the 2022 International Conference on Intelligent Medicine and Health
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