Pub Date : 1900-01-01DOI: 10.56439/jcmsr.2022.1102
M. Chan, Kenneth Ming Foo Nah, Benjamin Tze Keong Ding, T. Wong, C. Y. Kau
Background: Unicompartmental knee arthroplasty (UKA) is effective in the treatment of symptomatic unicompartmental knee osteoarthritis. However, ideal limb alignment and acceptable changes of alignment remains contentious. Purpose: The purpose of this study is to look at the impact of post-operative mechanical limb alignment on short term functional outcomes in an Asian population. Methods: We performed a retrospective review of all mobile bearing, Oxford UKAs performed from July 2016 to January 2019 by a single-surgeon (43 patients, 47 knees). Pre- and post-operative weight bearing radiographic parameters were measured, as well as functional assessments via Oxford knee society (OKS) scores and the original Knee society score (KSS). Results: The post-operative mechanical axis mean was varus 4.3° (range valgus 2° to varus 10°), with a mean correction of 4.4° towards valgus. All our patients had an improvement in functional scores and range of movement post-operatively, however, patients with pre-operative alignment of varus 15° did not meet the cut off for minimal important change (MIC) in OKS scores. More varus pre-operative alignment resulted in a larger degree of change in limb alignment post-operatively. A larger change in alignment was also associated with higher satisfaction scores in patients. Conclusion: Post-operative limb alignment of up to 10° varus does not compromise short term functional outcome scores in medial UKA. Caution is advised when selecting patients with varus 15° and above for UKA as they may not be able to achieve a minimal important change in functional scores post-operatively.
{"title":"Effect of Limb Alignment in Medial Unicompartmental Knee Arthroplasty on Functional Outcomes and Patient Satisfaction","authors":"M. Chan, Kenneth Ming Foo Nah, Benjamin Tze Keong Ding, T. Wong, C. Y. Kau","doi":"10.56439/jcmsr.2022.1102","DOIUrl":"https://doi.org/10.56439/jcmsr.2022.1102","url":null,"abstract":"Background: Unicompartmental knee arthroplasty (UKA) is effective in the treatment of symptomatic unicompartmental knee osteoarthritis. However, ideal limb alignment and acceptable changes of alignment remains contentious. Purpose: The purpose of this study is to look at the impact of post-operative mechanical limb alignment on short term functional outcomes in an Asian population. Methods: We performed a retrospective review of all mobile bearing, Oxford UKAs performed from July 2016 to January 2019 by a single-surgeon (43 patients, 47 knees). Pre- and post-operative weight bearing radiographic parameters were measured, as well as functional assessments via Oxford knee society (OKS) scores and the original Knee society score (KSS). Results: The post-operative mechanical axis mean was varus 4.3° (range valgus 2° to varus 10°), with a mean correction of 4.4° towards valgus. All our patients had an improvement in functional scores and range of movement post-operatively, however, patients with pre-operative alignment of varus 15° did not meet the cut off for minimal important change (MIC) in OKS scores. More varus pre-operative alignment resulted in a larger degree of change in limb alignment post-operatively. A larger change in alignment was also associated with higher satisfaction scores in patients. Conclusion: Post-operative limb alignment of up to 10° varus does not compromise short term functional outcome scores in medial UKA. Caution is advised when selecting patients with varus 15° and above for UKA as they may not be able to achieve a minimal important change in functional scores post-operatively.","PeriodicalId":250301,"journal":{"name":"Journal of Clinical Medicine & Surgery","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115209391","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56439/jcmsr.2022.1105
Dumitrache Marieta, Lascu Rodica
Behcet’s syndrome is an inflammatory, chronic, recurrent, multisystemic disease, common in men 25-40 years of age, with immunological determinism (including autoimmune) in the presence of infectious (bacterial) triggering agents and genetic involvement through the presence of HLA-B51. Behcet’s syndrome is characterized by a symptomatic triad of: recurrent nongranulomatous uveitis with hypopyon, oral and genital ulcers, and skin changes. Iridocyclitis (anterior uveitis) with acute, recurrent hypopyon is the most common ocular manifestation in Behcet’s syndrome and progresses to unpredictable outbreaks with sequelae and severe complications that cause loss / loss of vision. Ocular manifestations in Behcet’s syndrome are also accompanied by posterior pole involvement with posterior uveitis, venous and arterial occlusive vasculitis, necrotizing retinitis, macular edema, cystoid macular edema, which accentuates the decrease / loss of vision.Treatment of Behcet’s syndrome should be adapted to the chronic course of the disease and should be aggressive from the outset through systemic drug combinations: corticosteroid / immunosuppressive / immunomodulatory therapy and appropriate ophthalmic treatment: cycloplegics, antiglaucoma eye drops, filter surgery, cataract surgery, cataract surgery under cortisone protection, endoocular surgery, laser photocoagulation. Ophthalmologist / internist interdisciplinary collaboration is required.
{"title":"Eye Manifestations in Behcet’s Syndrome","authors":"Dumitrache Marieta, Lascu Rodica","doi":"10.56439/jcmsr.2022.1105","DOIUrl":"https://doi.org/10.56439/jcmsr.2022.1105","url":null,"abstract":"Behcet’s syndrome is an inflammatory, chronic, recurrent, multisystemic disease, common in men 25-40 years of age, with immunological determinism (including autoimmune) in the presence of infectious (bacterial) triggering agents and genetic involvement through the presence of HLA-B51. Behcet’s syndrome is characterized by a symptomatic triad of: recurrent nongranulomatous uveitis with hypopyon, oral and genital ulcers, and skin changes. Iridocyclitis (anterior uveitis) with acute, recurrent hypopyon is the most common ocular manifestation in Behcet’s syndrome and progresses to unpredictable outbreaks with sequelae and severe complications that cause loss / loss of vision. Ocular manifestations in Behcet’s syndrome are also accompanied by posterior pole involvement with posterior uveitis, venous and arterial occlusive vasculitis, necrotizing retinitis, macular edema, cystoid macular edema, which accentuates the decrease / loss of vision.Treatment of Behcet’s syndrome should be adapted to the chronic course of the disease and should be aggressive from the outset through systemic drug combinations: corticosteroid / immunosuppressive / immunomodulatory therapy and appropriate ophthalmic treatment: cycloplegics, antiglaucoma eye drops, filter surgery, cataract surgery, cataract surgery under cortisone protection, endoocular surgery, laser photocoagulation. Ophthalmologist / internist interdisciplinary collaboration is required.","PeriodicalId":250301,"journal":{"name":"Journal of Clinical Medicine & Surgery","volume":"89 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114290283","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56439/jcmsr.2022.1104
J. Paladino, A. S. Simões, A. Hidaka, Renan Murata Hayashi, Alexandre Sacchetti Bezerra
Purpose: The aim of this report was to conduct a systematic review of corpus cavernosum abscess case reports documenting the etiological agents and outcomes following treatment. Materials and Methods: We searched the Medline, Embase, and Cochrane databases for English-language articles published until September 2021 and performed a systematic review according to the 2020 PRISMA protocol. The primary outcome was to determine the erectile dysfunction rate, and the secondary outcome was to report the presence or worsening of penile deviation following corpus cavernosum abscess management. Results: We found 376 reports and included 41 studies with 42 patients in the systematic review analysis. Thirteen cases (30.9%) reported a first episode or worsening of erectile dysfunction after hospital discharge; five cases (11.9%) developed or had an exacerbated penile deviation during the follow-up. Conclusions: It is not possible carry out a systematic review with the current literature. Further prospective studies evaluating the proportion of compromised tissue, standardized therapeutic measures, and adequate follow-up should be conducted to better elucidate proper care for these patients.
{"title":"Integrative Review of Case Reports of Corpus Cavernosum Abscess","authors":"J. Paladino, A. S. Simões, A. Hidaka, Renan Murata Hayashi, Alexandre Sacchetti Bezerra","doi":"10.56439/jcmsr.2022.1104","DOIUrl":"https://doi.org/10.56439/jcmsr.2022.1104","url":null,"abstract":"Purpose: The aim of this report was to conduct a systematic review of corpus cavernosum abscess case reports documenting the etiological agents and outcomes following treatment. Materials and Methods: We searched the Medline, Embase, and Cochrane databases for English-language articles published until September 2021 and performed a systematic review according to the 2020 PRISMA protocol. The primary outcome was to determine the erectile dysfunction rate, and the secondary outcome was to report the presence or worsening of penile deviation following corpus cavernosum abscess management. Results: We found 376 reports and included 41 studies with 42 patients in the systematic review analysis. Thirteen cases (30.9%) reported a first episode or worsening of erectile dysfunction after hospital discharge; five cases (11.9%) developed or had an exacerbated penile deviation during the follow-up. Conclusions: It is not possible carry out a systematic review with the current literature. Further prospective studies evaluating the proportion of compromised tissue, standardized therapeutic measures, and adequate follow-up should be conducted to better elucidate proper care for these patients.","PeriodicalId":250301,"journal":{"name":"Journal of Clinical Medicine & Surgery","volume":"4 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134333128","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56439/jcmsr.2022.1101
Wu Hongbo, Zhao Zhang
Human forkhead boxl2 (FOXL2) gene is closely related to female ovarian function. Mutations in FOXL2 gene often lead to BPES syndrome. BPES is divided into POF (BPES type I) and non POF (BPES type II). This case report shows that when FOXL2 gene is combined with PADI6 gene mutation, the patient may have obstacles to egg maturation in addition to premature ovarian failure, resulting in the inability of the patient to obtain embryos during art, which eventually leads to the inability of the patient to obtain pregnancy.
{"title":"A Case Report of Primary Infertility with BPES Syndrome with FOXL2 Gene Mutation and PADI6 Gene Mutation","authors":"Wu Hongbo, Zhao Zhang","doi":"10.56439/jcmsr.2022.1101","DOIUrl":"https://doi.org/10.56439/jcmsr.2022.1101","url":null,"abstract":"Human forkhead boxl2 (FOXL2) gene is closely related to female ovarian function. Mutations in FOXL2 gene often lead to BPES syndrome. BPES is divided into POF (BPES type I) and non POF (BPES type II). This case report shows that when FOXL2 gene is combined with PADI6 gene mutation, the patient may have obstacles to egg maturation in addition to premature ovarian failure, resulting in the inability of the patient to obtain embryos during art, which eventually leads to the inability of the patient to obtain pregnancy.","PeriodicalId":250301,"journal":{"name":"Journal of Clinical Medicine & Surgery","volume":"205 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123059015","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 1900-01-01DOI: 10.56439/jcmsr.2022.1103
T. F. Hernandez, Richard Alexander Sera Blanco, Teresa Sandra Erice Rivero, Oreste Mojena Mojena, R. R. Jimenez, D. Concepción
Background: Covid-19 infected pregnant women has been reported worst outcome than non-pregnant due to physiological and immunological changes mainly in the third trimester of pregnancy. Methods: Observational analytic retrospective study with Covid-19 infected 411 women, whose ranges of age were between 18 to 52 years old divided in two groups; 84 pregnant and 327 non-pregnant admitted in The Cuban Hospital of Qatar, since April 1st to June 30th of 2020. It was aimed to compare both groups according to clinical, laboratory, radiological and main outcomes. Analysis of frequencies, Ji Square, Variance and Odds Ratio were performed. Results: Pregnant tended to be younger and predominated third trimester of pregnancy; obesity, vitamin D deficiency and asymptomatic infection prevailed in pregnant and were significant. Fever and cough were more frequent in non-pregnant. Chest X ray showed Focal Bilateral lesions prevailed in non-pregnant; most of pregnant did not do X rays. D- dimer and alkaline phosphatase were higher in pregnant, alanine amine transferase was higher in non-pregnant. 4 to 7 days of hospital stay predominated in pregnant. Oxygen therapy, moderate and severe respiratory distress and intensive care unit admission were predominant in pregnant. No lethality was observed in pregnant with Covid-19 infection. Conclusion: Covid-19 pregnant are younger and has higher probability of asymptomatic disease; but they have higher risk of co-morbidities, respiratory failure, intensive care admission and mechanical ventilation; mortality risk is higher in non-pregnant.
{"title":"Comparison of Pregnant and Non-pregnant Women With COVID-19 Infection","authors":"T. F. Hernandez, Richard Alexander Sera Blanco, Teresa Sandra Erice Rivero, Oreste Mojena Mojena, R. R. Jimenez, D. Concepción","doi":"10.56439/jcmsr.2022.1103","DOIUrl":"https://doi.org/10.56439/jcmsr.2022.1103","url":null,"abstract":"Background: Covid-19 infected pregnant women has been reported worst outcome than non-pregnant due to physiological and immunological changes mainly in the third trimester of pregnancy. Methods: Observational analytic retrospective study with Covid-19 infected 411 women, whose ranges of age were between 18 to 52 years old divided in two groups; 84 pregnant and 327 non-pregnant admitted in The Cuban Hospital of Qatar, since April 1st to June 30th of 2020. It was aimed to compare both groups according to clinical, laboratory, radiological and main outcomes. Analysis of frequencies, Ji Square, Variance and Odds Ratio were performed. Results: Pregnant tended to be younger and predominated third trimester of pregnancy; obesity, vitamin D deficiency and asymptomatic infection prevailed in pregnant and were significant. Fever and cough were more frequent in non-pregnant. Chest X ray showed Focal Bilateral lesions prevailed in non-pregnant; most of pregnant did not do X rays. D- dimer and alkaline phosphatase were higher in pregnant, alanine amine transferase was higher in non-pregnant. 4 to 7 days of hospital stay predominated in pregnant. Oxygen therapy, moderate and severe respiratory distress and intensive care unit admission were predominant in pregnant. No lethality was observed in pregnant with Covid-19 infection. Conclusion: Covid-19 pregnant are younger and has higher probability of asymptomatic disease; but they have higher risk of co-morbidities, respiratory failure, intensive care admission and mechanical ventilation; mortality risk is higher in non-pregnant.","PeriodicalId":250301,"journal":{"name":"Journal of Clinical Medicine & Surgery","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"1900-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126201094","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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