{"title":"Autophagy","authors":"Kohji Takei, Hiroshi Yamada","doi":"10.4044/joma.135.92","DOIUrl":"https://doi.org/10.4044/joma.135.92","url":null,"abstract":"","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"6 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136375736","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"The 2016 Incentive Award of the Okayama Medical Association in Neuroscience (2016 Niimi Prize)","authors":"Tatsuya Sasaki","doi":"10.4044/JOMA.130.5","DOIUrl":"https://doi.org/10.4044/JOMA.130.5","url":null,"abstract":"","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"130 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2018-04-02","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130203305","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Q9 ・Q10・Q11","authors":"岡山医学会","doi":"10.4044/JOMA.128.129","DOIUrl":"https://doi.org/10.4044/JOMA.128.129","url":null,"abstract":"","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"141 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128976184","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"新教育技法「チーム基盤型学習（TBL）」の有用性","authors":"M. Suno","doi":"10.4044/JOMA.128.125","DOIUrl":"https://doi.org/10.4044/JOMA.128.125","url":null,"abstract":"","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"197 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132329756","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"平成27年度岡山医学会賞 脳神経研究奨励賞（新見賞）","authors":"A. Toyoshima","doi":"10.4044/JOMA.128.95","DOIUrl":"https://doi.org/10.4044/JOMA.128.95","url":null,"abstract":"","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2016-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128298025","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to define the histopathological change and immunological response occurring as a result of testicular fine needle aspirations (TEFNAs) in C3H/HeN mice. TEFNA (one-, five-, or twenty-time aspiration) from the left testis was performed on day 0, and bilateral testes were examined histologically on days 21 and 49. Delayed-type hypersensitivity (DTH) was measured as the immunological response. Significant reduction of left testicular weight was observed only in the twenty-time aspiration group, on days 21 and 49. Histological examinations in the left testes showed a significantly high incidence of spermatogenetic disturbance with focal chronic inflammation and degenerative changes on day 21 and 49 after twenty-time TEFNA. Similar but less extensive changes were noted after five-time TEFNA. As for the weight and histology of the right testes, there was no significant change after the left-side TEFNA treatments. However, we revealed that the DTH response to autologous testicular cells was significantly elevated in the twenty-time aspiration group on day 21. In this animal model, TEFNA caused definite damage to the seminiferous tubules and induced DTH against testicular cells. Further study may be required to determine the clinical relevance of such findings to the testes of azoospermic men treated with TEFNA.
{"title":"Testicular fine needle aspirations cause histological injury and immunological response in mouse testis","authors":"H. Tsuboi","doi":"10.4044/JOMA.120.49","DOIUrl":"https://doi.org/10.4044/JOMA.120.49","url":null,"abstract":"The purpose of this study was to define the histopathological change and immunological response occurring as a result of testicular fine needle aspirations (TEFNAs) in C3H/HeN mice. TEFNA (one-, five-, or twenty-time aspiration) from the left testis was performed on day 0, and bilateral testes were examined histologically on days 21 and 49. Delayed-type hypersensitivity (DTH) was measured as the immunological response. Significant reduction of left testicular weight was observed only in the twenty-time aspiration group, on days 21 and 49. Histological examinations in the left testes showed a significantly high incidence of spermatogenetic disturbance with focal chronic inflammation and degenerative changes on day 21 and 49 after twenty-time TEFNA. Similar but less extensive changes were noted after five-time TEFNA. As for the weight and histology of the right testes, there was no significant change after the left-side TEFNA treatments. However, we revealed that the DTH response to autologous testicular cells was significantly elevated in the twenty-time aspiration group on day 21. In this animal model, TEFNA caused definite damage to the seminiferous tubules and induced DTH against testicular cells. Further study may be required to determine the clinical relevance of such findings to the testes of azoospermic men treated with TEFNA.","PeriodicalId":250334,"journal":{"name":"Journal of Okayama Medical Association","volume":"15 12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2008-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127670536","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
京公网安备 11010802042870号
京ICP备2023020795号-1
扫码关注我们
求助内容：
应助结果提醒方式：