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A Case Report of Conversion Catatonia 转换性紧张症1例报告
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.12
Shailja Singh, Nayab Anjum, Zeba Khan, M. Reyazuddin
Catatonia is characterized by marked psychomotor disturbance and was first described by Karl Ludwig Kaulbaum in 1874.1 Later, it was evaluated as a subtype of schizophrenia. After the 1960s, it was revealed that other conditions can also cause catatonia.2 Gelenberg (1976) said there could be more than 40 cases that could cause catatonia and many new ones have emerged since then.3 Previous data suggest that catatonia is more common in mood disorders than in schizophrenia. The other causes of catatonia can be due to medical causes like endocrine disorders, infections, electrolyte imbalance, epilepsy, and traumatic brain injury. An excessive dosage of drugs or substances like cocaine, ecstasy, disulfiram, and levetiracetam can also result in catatonia.4,5
紧张症以明显的精神运动障碍为特征,于1874年由卡尔·路德维希·考尔鲍姆首次描述。后来,它被评估为精神分裂症的一种亚型。20世纪60年代以后,发现其他情况也可引起紧张症Gelenberg(1976)说可能有超过40个病例可以引起紧张症,并且从那以后出现了许多新的病例先前的数据表明,紧张症在情绪障碍中比在精神分裂症中更常见。紧张症的其他原因可能是由于医学原因,如内分泌紊乱、感染、电解质失衡、癫痫和创伤性脑损伤。过量服用可卡因、摇头丸、双硫仑和左乙拉西坦等药物或物质也会导致紧张症
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引用次数: 0
Nonencephalopathic Psychiatric Manifestations (NEPM) and Response to Niacin in Pellagra: A Scoping Review 非脑病精神表现(NEPM)和对烟酸的反应糙皮病:一个范围审查
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.08
R. Sutar, Devendra S. Basera, Ashish Pakhre, Pooja Chaudhary, A. Lahiri
Psychiatric manifestations of pellagra could be subtle but important to recognize in clinical practice. These may vary from non-syndromic symptoms of anxiety, depression, and psychosis to pellagrous encephalopathy. The course and outcome of pellagra’s non-encephalopathic psychiatric manifestations (NEPM) are variable and have not received much attention. Therefore, a review in this regard is deemed necessary to understand the evolution of psychiatric symptoms and possible neurochemical changes produced in pellagra. A focused scoping review of the literature using Preferred Reporting Items for Systematic reviews and Meta-Analyses- extension for Scoping Reviews (PRISMA-ScR) guidelines was carried out to chart the results of studies to find out the characteristic nature of NEPM, role of niacin, and underlying etiopathogenesis. The review included 12 studies comprising 271 participants. Depressive and insomnia symptoms were the most frequent manifestations of NEPM followed by anxiety, thought disorder, psychomotor agitation, hallucinations, confusion, and disorientation. Alcohol use remains the most common cause of NEPM in pellagra, followed by nutritional deficiency. The alteration in the kynurenine pathway is a probable mechanism implicated in the NEPM of pellagra and future research should explore the role of niacin replacement in such patients. The findings of the review incite further discussion and research on biomarkers for patients with pellagra and subtype of patients with depression who share a common immune-inflammatory pathway.
糙皮病的精神表现可能是微妙的,但在临床实践中很重要的认识。这些症状可能从焦虑、抑郁和精神病等非综合征症状到糙皮性脑病不等。糙皮病的非脑病性精神表现(NEPM)的病程和结局是多变的,并没有得到太多的关注。因此,有必要对这方面进行综述,以了解糙皮病精神症状的演变和可能产生的神经化学变化。使用首选报告项目进行系统评价和荟萃分析扩展范围评价(PRISMA-ScR)指南对文献进行重点范围评价,以绘制研究结果图表,以找出NEPM的特征性质、烟酸的作用和潜在的发病机制。该综述包括12项研究,包括271名参与者。抑郁和失眠症状是NEPM最常见的表现,其次是焦虑、思维障碍、精神运动激动、幻觉、混乱和定向障碍。酒精使用仍然是糙皮病中NEPM的最常见原因,其次是营养缺乏。犬尿氨酸通路的改变可能与糙皮病的NEPM有关,未来的研究应探讨烟酸替代在这类患者中的作用。该综述的发现激发了对糙皮病患者和抑郁症亚型患者的生物标志物的进一步讨论和研究,这些患者具有共同的免疫炎症途径。
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引用次数: 0
Brain Exchange: Bidirectional Flux of Medical Personnel to Ensure Equitable Distribution of Resources between Developed and Developing Countries 人才交换:医疗人员的双向流动,以确保发达国家和发展中国家之间资源的公平分配
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.10
Ganesh Shanker, Sankalp Dixit, A. Tripathi, Anurag Senger, G. Saha, O. Singh, Tarun Yadav
This article is intended to address the plummeting numbers of trained medical personnel in developing countries due to exodus to developed lands often termed as ‘brain drain’ and to put forth ideas and suggestions that turn this brain drain into ‘brain exchange’ thereby benefiting both the donor and the recipient countries. A few suggestions presented here may help in creating an equilibrium of such efflux and influx of such medical personnel, thus completing the so-called ‘brain circulation.
这篇文章旨在解决发展中国家训练有素的医疗人员数量急剧下降的问题,这是由于大量人员涌向发达国家,通常被称为“人才流失”,并提出一些想法和建议,将这种人才流失转化为“人才交流”,从而使捐助国和受援国都受益。这里提出的一些建议可能有助于使这类医务人员的流出和流入达到平衡,从而完成所谓的“人才循环”。
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引用次数: 0
Is it the Time to take a Re-look at the Telepsychiatry Operational Guidelines- 2020? 是时候重新审视2020年远程精神病学操作指南了吗?
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.09
Arghya Pal
Our reliance on tele-health services has increased considerably over the last couple of years since the advent of the COVID-19 pandemic. It has changed the landscape of psychiatric practice considerably. The telepsychiatry operational guidelines were published by a collaboration of leading governing bodies to provide explicit structured guideline regarding the same. However, the experience of using this guideline over the last 2 years has brought forth a few limitations which have been highlighted in the current manuscript. Recommendations based on the review have also been provided.
自2019冠状病毒病大流行以来,我们对远程医疗服务的依赖在过去几年中大大增加。它极大地改变了精神病学实践的面貌。远程精神病学操作指南是由主要理事机构合作出版的,旨在就此提供明确的结构化指南。然而,在过去两年中使用该指南的经验带来了一些局限性,这些局限性在当前的手稿中得到了强调。还根据审查结果提出了建议。
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引用次数: 0
Irritable Bowel syndrome and Psychiatric Comorbidities: A narrative review 肠易激综合征和精神合并症:叙述性回顾
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.06
Ankita Saroj, A. Tripathi, S. Rungta
Irritable bowel syndrome (IBS) is the most commonly diagnosed illness by gastroenterologists. These symptoms occur widely in the general population at all ages and in both sexes. The condition is a considerable health-care burden, accounting for approximately half of all referrals to gastrointestinal clinics. The prevalence of IBS varies according on geographic region, demographic, and diagnostic criteria employed. IBS pathogenesis is complicated and poorly understood. Gut microbiota, small intestinal bacterial overgrowth (SIBO), visceral hypersensitivity, disruption of the gut-brain axis, psychosocial distress, and altered GI motility all are proposed as potential risk factors. Inflammatory bowel syndrome (IBS) is associated with considerable psychosocial comorbidities, which have an impact on patient quality of life, disease progression, and health-care expenditures. The present article reviews the latest evidence on the aetiology IBS, with a focus on psychiatric comorbidities and available management available.
肠易激综合征(IBS)是胃肠病学家最常诊断的疾病。这些症状广泛发生在所有年龄和性别的普通人群中。这种情况是一个相当大的保健负担,约占所有转介到胃肠诊所的一半。肠易激综合征的患病率因地理区域、人口统计学和所采用的诊断标准而异。肠易激综合征的发病机制复杂且知之甚少。肠道菌群、小肠细菌过度生长(SIBO)、内脏过敏、肠-脑轴破坏、社会心理困扰和胃肠道运动改变都被认为是潜在的危险因素。炎症性肠综合征(IBS)与相当多的社会心理合并症相关,这些合并症对患者的生活质量、疾病进展和卫生保健支出产生影响。本文回顾了IBS病因学的最新证据,重点介绍了精神疾病的合并症和现有的治疗方法。
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引用次数: 0
Pharmacomicrobiomics: Another Contributor of Inter-Individual Variations To Drug Response 药物微生物组学:药物反应的个体差异的另一个贡献者
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.01
A. Tripathi
Gut-brain axis is now a commonly discussed concept in a variety of clinical contexts including its well-known importance in neuropsychiatric disorders. Gut microbiota is a diverse population of microorganisms containing bacteria, yeast, protozoa, parasite, helminth, viruses, etc.
肠脑轴现在是一个经常讨论的概念,在各种临床背景下,包括它在神经精神疾病中众所周知的重要性。肠道菌群是由细菌、酵母菌、原生动物、寄生虫、蠕虫、病毒等组成的多种微生物群。
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引用次数: 0
Socio-demographic and Clinical Profile of Suicide Attempters attending a Tertiary Care Hospital: A Cross-sectional Study 三级医院自杀未遂者的社会人口学和临床特征:一项横断面研究
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.03
V. Gupta, A. Akanksha, S. A. Azmi, M. Reyazuddin, Rehan Mateen
BACKGROUND: Suicide attempts are one of the most common psychiatric crises. Suicide attempts are thought to be the most accurate determinants of completed suicide. A variety of circumstances causes suicide attempts. Although mental illness and extreme stress have long been linked to suicide, the socio-demographic and clinical features of those who attempt suicide can also reveal suicidal intent.OBJECTIVES: The aim of the study was to explore the socio-demographic factors and the clinical profile of suicide attempters.METHOD: The present study was conducted in the Department of Psychiatry, Jawahar Lal Nehru Medical College and Hospital, Aligarh, Uttar Pradesh. Suicide attempters referred for psychiatric evaluation from various hospital departments from December 2018 to November 2019 were evaluated after proper stabilization. Details including socio-demographic data and psychiatric diagnosis were tabulated and analyzed using SPSS-16.RESULT: In our study, out of 80 subjects, maximum suicide attempters (71.2%) belonged to the age group of 18-30 years, most of whom were females (51.2%), mostly married (65%), followed the Hindu religion (66.3%), equally distributed in a rural and urban area (50%), literate (76.2%), unemployed (56.2%), of the lower middle class (48.8%), living in a nuclear family (46.2%). Of all the methods, the most commonly used method was ingestion of insecticides/ pesticides (38.7%), and most attempters had interpersonal issues with their spouse (38.8%) and had some psychiatric comorbidity (56.3%).CONCLUSION: Suicide attempts are common among the young population. Poisoning is the most popular mode, with Organophosphorus compounds being the most common in our study. As a result, patients require psychiatric care. Self-harm can be reduced by promoting healthy coping strategies and reducing stress. In a nation like India, where established mental health facilities are rare and stigmatized, it is also essential to convey enough information to people from lower socio-economic backgrounds.
背景:自杀企图是最常见的精神危机之一。自杀企图被认为是自杀完成的最准确的决定因素。各种各样的情况会导致自杀企图。虽然精神疾病和极度压力长期以来一直与自杀有关,但企图自杀的人的社会人口统计学和临床特征也可以揭示自杀意图。目的:本研究的目的是探讨自杀未遂者的社会人口学因素和临床特征。方法:本研究在北方邦阿利格尔贾瓦哈尔·拉尔·尼赫鲁医学院精神科进行。2018年12月至2019年11月,在各医院部门进行精神评估的自杀未遂者在适当稳定后进行评估。包括社会人口统计数据和精神病学诊断在内的细节被制成表格,并使用SPSS-16进行分析。结果:在我们的研究中,80名研究对象中,自杀未遂者最多(71.2%)属于18-30岁年龄组,其中以女性居多(51.2%),以已婚居多(65%),信仰印度教(66.3%),城乡平均分布(50%),识字(76.2%),失业(56.2%),中下层(48.8%),生活在核心家庭(46.2%)。最常用的方法是服用杀虫剂/农药(38.7%),大多数自杀未遂者与配偶存在人际关系问题(38.8%),并伴有精神疾病(56.3%)。结论:自杀企图在年轻人中很常见。中毒是最常见的方式,在我们的研究中,有机磷化合物是最常见的。因此,病人需要精神治疗。自我伤害可以通过促进健康的应对策略和减轻压力来减少。在印度这样的国家,已建立的精神卫生机构很少,而且名声不佳,向社会经济背景较低的人传达足够的信息也很重要。
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引用次数: 0
Management of Children with Autism Spectrum Disorder using Picture Exchange Communication System - A Pilot Study 使用图像交换通信系统管理自闭症谱系障碍儿童的初步研究
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.04
Preethy Susan Reni, Kadayam S. Kalyani, Aishwarya Nagarajan, Khaarthigha Senthilnathan
Aim: The aim of the study was to empirically assess the efficacy of Picture Exchange Communication System (PECS) in 5 children with autism spectrum disorder (ASD). This study was also intended to report parental feedback on using PECS with their children.Method: Purposive convenient sampling was used for this quasi-experimental study. Five nonverbal children who were diagnosed with mild to moderate autism spectrum disorder with a median age of 4.1 years were selected for the study. All the five participants who exhibited limited or no functional communication skills were recruited for the study. Exclusion criteria included presence of any syndrome or any significant medical conditions such as seizures. The pre-assessment and the post assessments after 24 sessions of PECS training were done using selected communicative function domains. Post therapy parental feedback was obtained concerning five categories which are communication intent, attention, behavioural issues, vocalization and ease of communication. Also frequency of initiation as observed in home settings was obtained by interview method.Results: Current study shows that all the children were able to use PECS spontaneously and independently without any physical prompts. Children were able to generalize PECS at home with ease and were able to initiate communication on their own using the pictures. The mothers of the children reported that they observed a drastic subsidence in children’s challenging behaviours and also improvement in their attention span. The findings from our study showed that PECS training is effective in improving the socio-communication skills in children with ASD who had restricted communication. On analysing the report, mothers stated that they were able to easily incorporate PECS at home with their child as it implements the use of actual pictures for communicative exchange. As PECS training paves the way for expression of the child’s needs, there was also a significant reduction in the children’s behavioural problems such as tantrums and other self-injurious behaviours.Conclusion: From this study, it can be concluded that PECS training is effective in improving various communicative temptations in socio-communication skills in children with ASD who have restricted communication. It was also noted that obtaining parental feedback periodically would help in generalization and it encourages the parents’ involvement in the child’s learning process.
目的:探讨图片交换沟通系统(PECS)在5例自闭症谱系障碍(ASD)患儿中的应用效果。本研究还旨在报告家长对孩子使用PECS的反馈。方法:采用有目的、方便的抽样方法进行准实验研究。五名被诊断为轻度至中度自闭症谱系障碍的非语言儿童被选为研究对象,他们的平均年龄为4.1岁。所有表现出有限或没有功能性沟通技巧的五名参与者都被招募参加研究。排除标准包括存在任何综合征或任何重大医疗状况,如癫痫发作。采用选定的交际功能域进行24次PECS训练后的前评估和后评估。治疗后父母反馈主要包括沟通意向、注意力、行为问题、发声和沟通难易等5个方面。此外,通过访谈法获得了在家庭环境中观察到的入会频率。结果:目前的研究表明,所有的孩子都能自发地、独立地使用PECS,而不需要任何身体提示。孩子们能够在家里轻松地概括PECS,并能够使用图片自己发起交流。孩子们的母亲报告说,她们观察到孩子们的挑战行为急剧下降,注意力持续时间也有所改善。我们的研究结果表明,PECS训练对改善沟通受限的ASD儿童的社会沟通技能是有效的。在对报告进行分析后,母亲们表示,由于PECS实现了使用实际图片进行交流,她们可以很容易地在家里与孩子一起使用PECS。由于PECS训练为孩子表达需求铺平了道路,孩子们的行为问题,如发脾气和其他自残行为也显著减少。结论:PECS训练可有效改善沟通受限的ASD儿童社会沟通技能中的各种沟通诱惑。也有人指出,定期获得父母的反馈将有助于泛化,并鼓励父母参与孩子的学习过程。
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引用次数: 0
Evaluation of Stress and its Associated Stressors Among Undergraduate Dental Students: A Questionnaire-based Study 牙科大学生压力及其相关压力源的评估:一项问卷调查
Pub Date : 2022-10-31 DOI: 10.55229/ijbs.v25i2.15
K. Madhavan, Nivethitha Karuppiah, Rajeswari ., P. Karthick, Saravanan Saravanan
Aim: To evaluate the stress and its associated stressors or stress factors among dental undergraduate students.Background: Stress is a subjective feeling that acts as a barrier to preventing his/her goal. Stress occurs in everyone’s life in every aspect of life due to enormous reasons, and so dental students are cited for facing various amounts of stress throughout their academics due to several reasons.Materials And Methods: This cross-sectional study was conducted among undergraduate students (including interns) in a self-financing dental college in Tiruvallur, India. A google survey was conducted to collect data regarding academic sessions, environmental issues, and profiles of socio-demographics.Results: Out of 500 dental undergraduates participating in the study, nearly 332(66%) students are stressed. Nearly two third of students have reported being stressed is a large number. The study has also found that students from the internship are under more stress while studying in college, possibly due to work pressure or fears of their future after graduation.Conclusion: Sociodemographic profile, academic matters (performance of the study, curriculum, and frequency of tests), stress predictors, and physical stressors such as physical problems, high expectations of parents, and family issues are revealed as reasons in this dental curriculum. Management programs in dental colleges should be developed to improve students’ psychological support and promote better psychological health and coping.
目的:探讨口腔医学本科学生的应激及其相关应激源或应激因素。背景:压力是一种主观感觉,是阻碍他/她实现目标的障碍。压力存在于每个人的生活中,存在于生活的各个方面,原因很多,所以牙科专业的学生在整个学习过程中都面临着各种各样的压力,原因有很多。材料与方法:本横断面研究在印度Tiruvallur一所自费牙科学院的本科生(包括实习生)中进行。谷歌调查收集了有关学术会议、环境问题和社会人口统计资料的数据。结果:在参与研究的500名牙科本科生中,近332名(66%)学生压力较大。近三分之二的学生表示压力很大。该研究还发现,实习学生在大学期间承受的压力更大,可能是由于工作压力或对毕业后未来的担忧。结论:社会人口特征、学术问题(学习表现、课程和测试频率)、压力预测因素和身体压力源(如身体问题、父母的高期望和家庭问题)被揭示为该牙科课程的原因。牙科院校应制定管理方案,改善学生的心理支持,促进学生的心理健康和应对。
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引用次数: 0
Intravenous Ketamine-induced Affective Switch in a Patient of Major Depressive Disorder with Suicidal Ideation: A Case Report 静脉注射氯胺酮诱导的有自杀意念的重度抑郁症患者的情感转换一例报告
Pub Date : 2022-09-26 DOI: 10.55229/ijbs.v25i2.14
Akanksha Varshney, Shravan Kumar, V. Gupta, Rehan Mateen, S. Azmi
In treatment-resistant unipolar and bipolar depression, there is increasing evidence to support the fast, although the short-lived antidepressant effect of ketamine, a non-competitive glutamate N-methyl-D-aspartate receptor antagonist. Ketamine has been shown to cause transient mood elevation or euphoria, dissociative symptoms and psychotomimetic effects when administered in unipolar or bipolar depression. Still, it has not been shown to cause an affective switch resulting in persistent hypomania/mania or a manic-like state. We report the case of a 47-year-old man who developed a switch to mania while receiving a sub-anaesthetic dosage of ketamine intravenously for his third episode of recurrent, non-psychotic severe major depression with suicidal ideation. This case indicates that a polarity switch should be acknowledged as a possible side effect when using ketamine for depression.
在治疗难治性单极和双相抑郁症中,越来越多的证据支持氯胺酮(一种非竞争性谷氨酸n-甲基- d -天冬氨酸受体拮抗剂)的快速而短暂的抗抑郁作用。氯胺酮已被证明在单极或双相抑郁症中使用时可引起短暂的情绪升高或欣快感、解离症状和拟精神作用。尽管如此,还没有证据表明它会引起情感上的转换,从而导致持续的轻躁狂/躁狂或躁狂样状态。我们报告了一个47岁的男子,他在接受亚麻醉剂量的氯胺酮静脉注射时,出现了躁狂的转变,因为他的第三次复发性,非精神病性严重抑郁症伴自杀意念。这个案例表明,当使用氯胺酮治疗抑郁症时,极性转换应该被认为是可能的副作用。
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引用次数: 0
期刊
Indian Journal of Behavioural Sciences
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