Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537227
R. S. Putra, Desi Arrunillah, Farikhatul Fitria, Nadia Ripki
Size distribution of gas bubbles were important factor in electroflotation systems because small bubbles increased the efficiency of floc floatation. The aimed in this study was to evaluate the digital microscope (DinoLite) for diameter measurement of gas bubble distribution on the electroflotation process. In this study, effects of constant voltage on size distribution of gas bubble were determined by 11.21 V and 31 V. The electroflotation system was designed by stainless steel cathode and titanium anode which was supplied by constant DC voltage for 30 minutes. The image of gas bubble was captured by DinoLite and then the size of gas bubble was measured by DinoCaptured 2.0 and free ImageJ software. These results were then compared and verified by correlation coefficient (R2) of linear regression equation. The results showed that applied voltage effects the average size of gas bubble distribution in electroflotation process. When low voltage (11 V) was applied, the average size of gas bubble formed in 0.01-0.09 mm2 both on cathode and anode surface. Meanwhile, the average size of gas bubble at 21 and 31 V tends to be in 0.01-0.09 and >0.1 mm2 on cathode and anode surface.
{"title":"Measurement of Gas Bubbles Distribution on Electroflotation Process Using Titanium and Stainless Steel Electrode with DinoCapture 2.0","authors":"R. S. Putra, Desi Arrunillah, Farikhatul Fitria, Nadia Ripki","doi":"10.1109/InHeNce52833.2021.9537227","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537227","url":null,"abstract":"Size distribution of gas bubbles were important factor in electroflotation systems because small bubbles increased the efficiency of floc floatation. The aimed in this study was to evaluate the digital microscope (DinoLite) for diameter measurement of gas bubble distribution on the electroflotation process. In this study, effects of constant voltage on size distribution of gas bubble were determined by 11.21 V and 31 V. The electroflotation system was designed by stainless steel cathode and titanium anode which was supplied by constant DC voltage for 30 minutes. The image of gas bubble was captured by DinoLite and then the size of gas bubble was measured by DinoCaptured 2.0 and free ImageJ software. These results were then compared and verified by correlation coefficient (R2) of linear regression equation. The results showed that applied voltage effects the average size of gas bubble distribution in electroflotation process. When low voltage (11 V) was applied, the average size of gas bubble formed in 0.01-0.09 mm2 both on cathode and anode surface. Meanwhile, the average size of gas bubble at 21 and 31 V tends to be in 0.01-0.09 and >0.1 mm2 on cathode and anode surface.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"87 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"124400631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537279
Anker Zhao, Wanyang Sun
Phenolamides (PAs) exist extensively in plants. They are comprised of the conjugation of a phenolic structure with polyamines or deaminated aromatic amino acids. They participate in multiple physiological process in plants, e.g. organ growth, adaptation and defense. However, this process is hindered by the existence of many different isomers of phenolamides and the lack of reference standards. A big problem is that it is time-consuming to process the data which leads to the identification of these compounds being incredibly inefficient. The purpose of this study is to establish a novel strategy to automatically annotate phenolamides by a machine learning model. The various typical phenolamides were synthesized according to the structural diversity of their building blocks. Liquid chromatography – mass spectrometry (LC-MS) was used to summarize the fragmentation patterns. A fragmentation pattern-based identification strategy was utilized and a machine learning model was developed by using Python script in order to identify hundreds of phenolamides in hours. The developed method was applied to identify phenolamides in herbal medicines and vegetables. These results will be useful for medicinal purposes.
{"title":"in silico Automatic Annotation of Phenolamides in Plants by Tandem Mass Spectra","authors":"Anker Zhao, Wanyang Sun","doi":"10.1109/InHeNce52833.2021.9537279","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537279","url":null,"abstract":"Phenolamides (PAs) exist extensively in plants. They are comprised of the conjugation of a phenolic structure with polyamines or deaminated aromatic amino acids. They participate in multiple physiological process in plants, e.g. organ growth, adaptation and defense. However, this process is hindered by the existence of many different isomers of phenolamides and the lack of reference standards. A big problem is that it is time-consuming to process the data which leads to the identification of these compounds being incredibly inefficient. The purpose of this study is to establish a novel strategy to automatically annotate phenolamides by a machine learning model. The various typical phenolamides were synthesized according to the structural diversity of their building blocks. Liquid chromatography – mass spectrometry (LC-MS) was used to summarize the fragmentation patterns. A fragmentation pattern-based identification strategy was utilized and a machine learning model was developed by using Python script in order to identify hundreds of phenolamides in hours. The developed method was applied to identify phenolamides in herbal medicines and vegetables. These results will be useful for medicinal purposes.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114033301","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537246
Laura Enika, L. Chiuman, A. N. Nasution, C. Ginting
Riskesdas in 2013 showed that 35.9% of the Indonesian population aged higher than 15 years had abnormal cholesterol levels. Lemon pepper has various pharmacological benefits. Therefore, this study aimed to determine the effectiveness of lemon pepper methanol extract as anti-dyslipidemia. This study is an experimental study using 24 rats divided into 6 different groups, including: normal (no intervention), control (Na CMC 0.5%), standard (simvastatin), Lemon Pepper Methanol Extract I (300 mg/kgBW), II (600 mg/kgBW), and III (1200 mg/kgBW). All groups, except the normal group, were given a high-fat diet (15 g/kg animal fat; 10 g/kg poultry egg yolk) and PTU (12.5 mg/day). The results showed that the highest dose of lemon pepper methanol extracts significantly reduced total cholesterol (151.75 ± 0.96 mg/dl), triglycerides (166.50 (162-179) mg/dl), and LDL cholesterol (68.50 ± 1.29 mg/dl) levels and significantly increased HDL levels (61.00 (60-100) mg/dl) compared to the control group. In addition, the lemon pepper methanol extract significantly reduced the levels of SGOT (P value same 0.029) and SGPT (P value smaller than 0.05) compared to the control group. Hence, it can be said that the methanol extract of lemon pepper has an anti-dyslipidemic effect and can prevent NAFLD.
{"title":"Anti-Dyslipidemia Activity from Lemon Pepper in PTU and High Fat Diet Induced Rats","authors":"Laura Enika, L. Chiuman, A. N. Nasution, C. Ginting","doi":"10.1109/InHeNce52833.2021.9537246","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537246","url":null,"abstract":"Riskesdas in 2013 showed that 35.9% of the Indonesian population aged higher than 15 years had abnormal cholesterol levels. Lemon pepper has various pharmacological benefits. Therefore, this study aimed to determine the effectiveness of lemon pepper methanol extract as anti-dyslipidemia. This study is an experimental study using 24 rats divided into 6 different groups, including: normal (no intervention), control (Na CMC 0.5%), standard (simvastatin), Lemon Pepper Methanol Extract I (300 mg/kgBW), II (600 mg/kgBW), and III (1200 mg/kgBW). All groups, except the normal group, were given a high-fat diet (15 g/kg animal fat; 10 g/kg poultry egg yolk) and PTU (12.5 mg/day). The results showed that the highest dose of lemon pepper methanol extracts significantly reduced total cholesterol (151.75 ± 0.96 mg/dl), triglycerides (166.50 (162-179) mg/dl), and LDL cholesterol (68.50 ± 1.29 mg/dl) levels and significantly increased HDL levels (61.00 (60-100) mg/dl) compared to the control group. In addition, the lemon pepper methanol extract significantly reduced the levels of SGOT (P value same 0.029) and SGPT (P value smaller than 0.05) compared to the control group. Hence, it can be said that the methanol extract of lemon pepper has an anti-dyslipidemic effect and can prevent NAFLD.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114151533","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537221
Amélia, Ermi Girsang, A. N. Nasution, C. Ginting
Skin aging is a complex natural phenomenon characterized by a progressive loss of structural integrity and physiological function of the skin. These changes manifest as visible wrinkling and loss of elasticity in the skin. This study aims to assess the anti-aging effectiveness of red spinach extract on increasing levels of collagen, elasticity, hydration, sebum, and pigment in male rats. A total of 25 rats were divided into 5 groups, each of which consisted of 5 white rats; control group (ointment base), red spinach extract ointment group 2.5%, 5%, 7.5%, and 10%. The results of phytochemical examination showed the presence of alkaloids, flavonoids, tannins and glycosides, with the total content of phenols, tannins, and flavonoids from the methanol extract of spinach leaves, respectively 20.22 GAE mg / gram extract, 0.09 QE mg / gram extract, and 20.83 TAE mg / gram extract. Changes in the level of skin hydration before and after treatment showed a significant change (P value less than 0.05) with the highest change found at a concentration of 10%, namely 64.84%. Changes in skin collagen levels before and after treatment showed significant changes (P value less than 0.05) with the highest change found at a concentration of 10%, namely 56.25%. Changes in the level of skin elasticity before and after treatment showed significant changes (P value less than 0.05) with the highest change found at a concentration of 10%, namely 46.30%. Changes in the level of skin pigmentation before and after treatment showed a significant change (P value less than 0.05) with the highest change found at a concentration of 10%, namely 35.97%. The highest percentage of decrease in sebum level among all groups given red spinach methanol extract ointment was indicated by the highest concentration of 10%, which was 40%. From the results of this study, it can be concluded that the red spinach leaf extract ointment has quite good anti-aging activity.
{"title":"Anti-Aging Effectiveness of Red Spinach Extract Ointment (Amaranthus Tricolor L.) Against Collagen, Elasticity, Hydration, Sebum, and Pigment Levels in Wistar Rats","authors":"Amélia, Ermi Girsang, A. N. Nasution, C. Ginting","doi":"10.1109/InHeNce52833.2021.9537221","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537221","url":null,"abstract":"Skin aging is a complex natural phenomenon characterized by a progressive loss of structural integrity and physiological function of the skin. These changes manifest as visible wrinkling and loss of elasticity in the skin. This study aims to assess the anti-aging effectiveness of red spinach extract on increasing levels of collagen, elasticity, hydration, sebum, and pigment in male rats. A total of 25 rats were divided into 5 groups, each of which consisted of 5 white rats; control group (ointment base), red spinach extract ointment group 2.5%, 5%, 7.5%, and 10%. The results of phytochemical examination showed the presence of alkaloids, flavonoids, tannins and glycosides, with the total content of phenols, tannins, and flavonoids from the methanol extract of spinach leaves, respectively 20.22 GAE mg / gram extract, 0.09 QE mg / gram extract, and 20.83 TAE mg / gram extract. Changes in the level of skin hydration before and after treatment showed a significant change (P value less than 0.05) with the highest change found at a concentration of 10%, namely 64.84%. Changes in skin collagen levels before and after treatment showed significant changes (P value less than 0.05) with the highest change found at a concentration of 10%, namely 56.25%. Changes in the level of skin elasticity before and after treatment showed significant changes (P value less than 0.05) with the highest change found at a concentration of 10%, namely 46.30%. Changes in the level of skin pigmentation before and after treatment showed a significant change (P value less than 0.05) with the highest change found at a concentration of 10%, namely 35.97%. The highest percentage of decrease in sebum level among all groups given red spinach methanol extract ointment was indicated by the highest concentration of 10%, which was 40%. From the results of this study, it can be concluded that the red spinach leaf extract ointment has quite good anti-aging activity.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"44 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129954776","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537284
L. Chiuman, C. Ginting, O. Yulizal, Suhartomi, Veranyca Chiuman
Diabetes mellitus is usually associated with oxidative stress which can initiate or promote chronic diabetic lesions in various organs. Reactive Oxygen Species accumulation affects liver tissue and may also cause Non-Alcoholic Fatty Liver Disease (NAFLD). Lemon pepper is an alternative medicine that is widely used in the Batak community. Therefore, this study was designed to determine the improvement of liver function from ethanolic extract of lemon (Zanthoxylum acanthopodium) in Wistar rats induced by streptozotocin. In the eksperiment, 25 rats which divided into five groups: control, standard, lemon pepper-1, 2, and 3 (250, 500, and 750 mg/kg BW, respectively) were used. After 14 days of intervention, the ALT and AST levels were measured in all rats. The results showed that the average percentage reduction in the AST levels in lemon pepper I, II, III, and standard groups were 2.64%, 35.76%, 43.59%, and 44.82%, respectively; The average percentage reduction in the ALT levels were 76.19%, 87.20%, 84.99%, and 88.39%, respectively. However, the decrease in each level showed that the increase in the AST level was better than the ALT. Overall it can be concluded that lemon pepper extract can improve the liver function of streptozotocin-induced wistar rats and the most effective dose of ethanolic extract of lemon fruit for improving liver function, especially ALT levels is 750 mg/kg BW.B
{"title":"Improvement of Liver Function from Lemon Pepper Fruit Ethanol Extract in Streptozotocin-Induced Wistar Rats","authors":"L. Chiuman, C. Ginting, O. Yulizal, Suhartomi, Veranyca Chiuman","doi":"10.1109/InHeNce52833.2021.9537284","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537284","url":null,"abstract":"Diabetes mellitus is usually associated with oxidative stress which can initiate or promote chronic diabetic lesions in various organs. Reactive Oxygen Species accumulation affects liver tissue and may also cause Non-Alcoholic Fatty Liver Disease (NAFLD). Lemon pepper is an alternative medicine that is widely used in the Batak community. Therefore, this study was designed to determine the improvement of liver function from ethanolic extract of lemon (Zanthoxylum acanthopodium) in Wistar rats induced by streptozotocin. In the eksperiment, 25 rats which divided into five groups: control, standard, lemon pepper-1, 2, and 3 (250, 500, and 750 mg/kg BW, respectively) were used. After 14 days of intervention, the ALT and AST levels were measured in all rats. The results showed that the average percentage reduction in the AST levels in lemon pepper I, II, III, and standard groups were 2.64%, 35.76%, 43.59%, and 44.82%, respectively; The average percentage reduction in the ALT levels were 76.19%, 87.20%, 84.99%, and 88.39%, respectively. However, the decrease in each level showed that the increase in the AST level was better than the ALT. Overall it can be concluded that lemon pepper extract can improve the liver function of streptozotocin-induced wistar rats and the most effective dose of ethanolic extract of lemon fruit for improving liver function, especially ALT levels is 750 mg/kg BW.B","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129639804","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537210
Meri Nova Marito Br.Sipahutar, O. S. Sitompul, Sutarman
Apriori algorithm is an algorithm to find a combination of items in a dataset that has a relationship value between items by paying attention to the minimum support and minimum confidence values. A common problem in the a priori algorithm is the formation of an item set when getting a large number of items from a dataset. The more items in a dataset, the more itemset will be formed. This will lead to increased storage space and poor algorithm performance. Some techniques can be applied to help correct these deficiencies, namely fuzzy logic. Fuzzy logic can normalize the items in the dataset by grouping the data according to the given rules. The formation of association rules using an a priori algorithm with fuzzy normalization obtained a total of 63 rules, a support value of 6.80%, and a confidence value of 88.4%. While the conventional a priori algorithm obtained a total of 13 rules, a support value of 6.80%, and a confidence value of 85%. Based on the results obtained, it can be concluded that the fuzzy normalization process on the a priori algorithm has a fairly good impact. The results obtained are not much different, but the difference can be seen from the number of rules and itemset formed.
{"title":"Association Rules Analysis Using Algorithm Apriori And Fuzzy Normalization","authors":"Meri Nova Marito Br.Sipahutar, O. S. Sitompul, Sutarman","doi":"10.1109/InHeNce52833.2021.9537210","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537210","url":null,"abstract":"Apriori algorithm is an algorithm to find a combination of items in a dataset that has a relationship value between items by paying attention to the minimum support and minimum confidence values. A common problem in the a priori algorithm is the formation of an item set when getting a large number of items from a dataset. The more items in a dataset, the more itemset will be formed. This will lead to increased storage space and poor algorithm performance. Some techniques can be applied to help correct these deficiencies, namely fuzzy logic. Fuzzy logic can normalize the items in the dataset by grouping the data according to the given rules. The formation of association rules using an a priori algorithm with fuzzy normalization obtained a total of 63 rules, a support value of 6.80%, and a confidence value of 88.4%. While the conventional a priori algorithm obtained a total of 13 rules, a support value of 6.80%, and a confidence value of 85%. Based on the results obtained, it can be concluded that the fuzzy normalization process on the a priori algorithm has a fairly good impact. The results obtained are not much different, but the difference can be seen from the number of rules and itemset formed.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"31 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127763823","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537244
R. D. Manurung, S. Ilyas, S. Hutahaean, R. Rosidah, R. H. Simanullang
Diabetes mellitus (DM), commonly known as a metabolic disease, is characterized by hyperglycemia caused by the inability of the pancreas to secrete the hormone insulin, impaired insulin action, or both. Hyperglycemia will usually increase Reactive Oxidative Stress and trigger oxidative stress so that it can interfere with every phase of wound healing. Vascular Endothelial Growth Factor (VEGF) plays a role in the angiogenesis process in providing nutrition to wound tissue. One of the natural herbal plants that has the ability to heal burns in DM patients is Andaliman (Zanthoxylum acanthopodium). This is because Andaliman contains terpenoids, flavonoids, tannins, and saponins. This study aims to determine the effectiveness of Andaliman nano herbal against VEGF protein during the healing process of burns in diabetic rats. In this study, Experiments were designed into two groups of burn rats: untreated and treated with Andaliman nano herbal. Treatment and surgery were performed on the days of 0, 4, 8, 12, and 16, respectively. Furthermore, the VEGF protein expression using immunohistochemical staining was analyzed. The results showed (Kruskal-Wallis test) that administration with the Andaliman nano herbal was highly effective in increasing VEGF expression from the day of 4 to day of 16 (p<0.05, p=0.000). It can be concluded that the nano herbal Andaliman is highly effective in increasing the expression of VEGF during the healing process of burns in diabetic rats.
{"title":"Effectivity of Nano herbal Andaliman (Zanthoxylum acanthopodium) to the Vascular Endothelial Growth Factor (VEGF) expression in burn wound in diabetic rats","authors":"R. D. Manurung, S. Ilyas, S. Hutahaean, R. Rosidah, R. H. Simanullang","doi":"10.1109/InHeNce52833.2021.9537244","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537244","url":null,"abstract":"Diabetes mellitus (DM), commonly known as a metabolic disease, is characterized by hyperglycemia caused by the inability of the pancreas to secrete the hormone insulin, impaired insulin action, or both. Hyperglycemia will usually increase Reactive Oxidative Stress and trigger oxidative stress so that it can interfere with every phase of wound healing. Vascular Endothelial Growth Factor (VEGF) plays a role in the angiogenesis process in providing nutrition to wound tissue. One of the natural herbal plants that has the ability to heal burns in DM patients is Andaliman (Zanthoxylum acanthopodium). This is because Andaliman contains terpenoids, flavonoids, tannins, and saponins. This study aims to determine the effectiveness of Andaliman nano herbal against VEGF protein during the healing process of burns in diabetic rats. In this study, Experiments were designed into two groups of burn rats: untreated and treated with Andaliman nano herbal. Treatment and surgery were performed on the days of 0, 4, 8, 12, and 16, respectively. Furthermore, the VEGF protein expression using immunohistochemical staining was analyzed. The results showed (Kruskal-Wallis test) that administration with the Andaliman nano herbal was highly effective in increasing VEGF expression from the day of 4 to day of 16 (p<0.05, p=0.000). It can be concluded that the nano herbal Andaliman is highly effective in increasing the expression of VEGF during the healing process of burns in diabetic rats.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"354 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132554367","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537236
G. L. K. Reddy, M. Manikandan, N. Murty
In most wearable devices, pulse rate (PR) is measured from photoplethysmogram (PPG) signal by using fast Fourier transform (FFT), autoregressive (AR), autocorrelation function (ACF) and peak counting methods. In this paper, we study accuracy and reliability of PR estimation by highlighting major drawbacks of these methods and optimal selection of measurement duration (10, 15, 30 or 60 s) for accurate measurement of PR from different morphological pulsatile patterns of normal and abnormal PPG signals. Evaluation results on the PPG signals taken from seven databases with two sampling rates (125 Hz and 25 Hz) demonstrate that the amplitude threshold (ATh) based PR estimation method is more accurate and lightweight as compared to the existing FFT-, AR- and ACF-based methods in terms of mean absolute error (MAE), Pearson coefficient (PC), Bland-Altman ratio (BAR), ve error ranges (ERs) (0-1, 2-5, 6-10, 11-25,>25 bpm) and computational load. The ATh- based method had the performance of MAE=0.61 bpm, PC=0.996, BAR=3.7% and ER>5 bpm of 1.57%, and outperforms the MAE, PC, BAR and ER>5 bpm values respectively of 2.74 bpm, 0.9432, 14.4% and 11.75% for FFT-based, the values of 3.96 bpm, 0.8028, 36.8%, and 8.07% for AR-based and the values of 2.15 bpm, 0.9607, 12.1% and 7.94% for ACF-based method. Results showed that the sampling rate and measurement duration impact the accuracy and computational load.
{"title":"Performance of Spectral, Autocorrelation and Peak Count Based PR Estimation Methods Under Normal/Abnormal PPG for Wearable Devices","authors":"G. L. K. Reddy, M. Manikandan, N. Murty","doi":"10.1109/InHeNce52833.2021.9537236","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537236","url":null,"abstract":"In most wearable devices, pulse rate (PR) is measured from photoplethysmogram (PPG) signal by using fast Fourier transform (FFT), autoregressive (AR), autocorrelation function (ACF) and peak counting methods. In this paper, we study accuracy and reliability of PR estimation by highlighting major drawbacks of these methods and optimal selection of measurement duration (10, 15, 30 or 60 s) for accurate measurement of PR from different morphological pulsatile patterns of normal and abnormal PPG signals. Evaluation results on the PPG signals taken from seven databases with two sampling rates (125 Hz and 25 Hz) demonstrate that the amplitude threshold (ATh) based PR estimation method is more accurate and lightweight as compared to the existing FFT-, AR- and ACF-based methods in terms of mean absolute error (MAE), Pearson coefficient (PC), Bland-Altman ratio (BAR), ve error ranges (ERs) (0-1, 2-5, 6-10, 11-25,>25 bpm) and computational load. The ATh- based method had the performance of MAE=0.61 bpm, PC=0.996, BAR=3.7% and ER>5 bpm of 1.57%, and outperforms the MAE, PC, BAR and ER>5 bpm values respectively of 2.74 bpm, 0.9432, 14.4% and 11.75% for FFT-based, the values of 3.96 bpm, 0.8028, 36.8%, and 8.07% for AR-based and the values of 2.15 bpm, 0.9607, 12.1% and 7.94% for ACF-based method. Results showed that the sampling rate and measurement duration impact the accuracy and computational load.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"101 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132995214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537247
Andrés D. Reina, José Cornejo, Sergio Galvis-Forero, Eduardo Guzman, Reynaldo Oliva-Hernández
Animals have been considered the forerunners of human-manned space travel. From the beginning, engineers and veterinarians have worked together to design technologies that support biological and physiological needs in microgravity conditions through the design and implementation of habitats as a means of transport and animal health monitoring systems in space. Therefore, the Division of Space Veterinary Medicine developed an international study in order to present a literature review of the innovative synergistic connection between aerospace engineering and veterinary medicine in space research and exploration. The studied species were selected according to their historical antecedents and scientific contributions based on their phylogenetic characteristics from the largest to the smallest scale. The primates due to its similarity to humans, the dog due to its behavior and social character, the rodent as a pioneering model in biomedical sciences and a section of other animals of deep interest. Also, the article presents life support and environmental control systems, which are designed to sustain life in space. Finally, this is the first research conducted in Latin America which summarizes the historical data related to animals in space.
{"title":"Animals and Technology in Space: A Perspective from Aerospace Engineering to Veterinary Medicine","authors":"Andrés D. Reina, José Cornejo, Sergio Galvis-Forero, Eduardo Guzman, Reynaldo Oliva-Hernández","doi":"10.1109/InHeNce52833.2021.9537247","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537247","url":null,"abstract":"Animals have been considered the forerunners of human-manned space travel. From the beginning, engineers and veterinarians have worked together to design technologies that support biological and physiological needs in microgravity conditions through the design and implementation of habitats as a means of transport and animal health monitoring systems in space. Therefore, the Division of Space Veterinary Medicine developed an international study in order to present a literature review of the innovative synergistic connection between aerospace engineering and veterinary medicine in space research and exploration. The studied species were selected according to their historical antecedents and scientific contributions based on their phylogenetic characteristics from the largest to the smallest scale. The primates due to its similarity to humans, the dog due to its behavior and social character, the rodent as a pioneering model in biomedical sciences and a section of other animals of deep interest. Also, the article presents life support and environmental control systems, which are designed to sustain life in space. Finally, this is the first research conducted in Latin America which summarizes the historical data related to animals in space.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132689214","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2021-07-14DOI: 10.1109/InHeNce52833.2021.9537265
I. Handayani, N. Folz
In the 21st century we face the severe impacts of climate change in agriculture including soil erosion, reduced soil quality, and lower crop productivity which threaten future food security and global sustainability. The food security challenge will become more difficult because the world will need to produce about 70% more food by 2050 to feed an estimated 9 billion people. Agriculture is also a major contributor to the climate problem, as it currently generates about 25% of total greenhouse gases. This percentage could rise substantially as other sectors reduce their emissions. On the other hand, agricultural land management offers a potential system to adapt to the world's changing climate. Various land management practices provide different abilities and capacities to mitigate climate change depending on factors such as soils, crops, soil amendments, tillage, landscape and cropping systems. Soil management focusing on carbon and nitrogen cycles as the driving forces for better soil quality will be discussed. The paper will provide an overview of accomplishing this management through the use of soil amendments, low-input agricultural systems, cropping systems, and precision agriculture. In addition, land conservation systems such as different tillage practices, crop rotations and land restoration technologies provide opportunities to reduce global climate change through improved soil carbon sequestration. This paper suggests that (1) increased productivity, (2) enhanced resilience and (3) reduced emissions are needed as outcomes from each management system. In conclusion, agricultural land management practices that improve carbon sequestration and soil functions through increased soil quality and soil health reduce soil erosion and support the resilience of cropping are necessary to sustain food security in a changing climate. Without considering climate-smart agriculture, our land will not support soil-water conservation sufficient to provide food for the world's global growing population.
{"title":"Adaptive Land Management for Climate-Smart Agriculture","authors":"I. Handayani, N. Folz","doi":"10.1109/InHeNce52833.2021.9537265","DOIUrl":"https://doi.org/10.1109/InHeNce52833.2021.9537265","url":null,"abstract":"In the 21st century we face the severe impacts of climate change in agriculture including soil erosion, reduced soil quality, and lower crop productivity which threaten future food security and global sustainability. The food security challenge will become more difficult because the world will need to produce about 70% more food by 2050 to feed an estimated 9 billion people. Agriculture is also a major contributor to the climate problem, as it currently generates about 25% of total greenhouse gases. This percentage could rise substantially as other sectors reduce their emissions. On the other hand, agricultural land management offers a potential system to adapt to the world's changing climate. Various land management practices provide different abilities and capacities to mitigate climate change depending on factors such as soils, crops, soil amendments, tillage, landscape and cropping systems. Soil management focusing on carbon and nitrogen cycles as the driving forces for better soil quality will be discussed. The paper will provide an overview of accomplishing this management through the use of soil amendments, low-input agricultural systems, cropping systems, and precision agriculture. In addition, land conservation systems such as different tillage practices, crop rotations and land restoration technologies provide opportunities to reduce global climate change through improved soil carbon sequestration. This paper suggests that (1) increased productivity, (2) enhanced resilience and (3) reduced emissions are needed as outcomes from each management system. In conclusion, agricultural land management practices that improve carbon sequestration and soil functions through increased soil quality and soil health reduce soil erosion and support the resilience of cropping are necessary to sustain food security in a changing climate. Without considering climate-smart agriculture, our land will not support soil-water conservation sufficient to provide food for the world's global growing population.","PeriodicalId":260400,"journal":{"name":"2021 IEEE International Conference on Health, Instrumentation & Measurement, and Natural Sciences (InHeNce)","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-07-14","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133200506","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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