Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0014-2
M. Sztanke, K. Pasternak, W. Bulikowski, M. Bacher, K. Kucharska, Wojciech Jankowski
{"title":"The influence of a high dose of ochratoxin A on some elements concentrations in skins with the fur of female rats","authors":"M. Sztanke, K. Pasternak, W. Bulikowski, M. Bacher, K. Kucharska, Wojciech Jankowski","doi":"10.2478/V10079-008-0014-2","DOIUrl":"https://doi.org/10.2478/V10079-008-0014-2","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123365876","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0012-4
J. Bury, A. Skrzypek, Elżbieta Mach-Lichota, A. Dabrowski
{"title":"Survivin in cancer diagnosis and therapy - a review","authors":"J. Bury, A. Skrzypek, Elżbieta Mach-Lichota, A. Dabrowski","doi":"10.2478/V10079-008-0012-4","DOIUrl":"https://doi.org/10.2478/V10079-008-0012-4","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126611284","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0011-5
M. Szewczyk, K. Pasternak
{"title":"Health resort rehabilitation of the cardiological patients","authors":"M. Szewczyk, K. Pasternak","doi":"10.2478/V10079-008-0011-5","DOIUrl":"https://doi.org/10.2478/V10079-008-0011-5","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133606178","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0013-3
M. Kiełczykowska, I. Musik, Anna Hordyjewska, A. Boguszewska, A. Lewandowska, K. Pasternak
{"title":"The influence of different doses of lithium administered to rats in drinking water on calcium homeostasis","authors":"M. Kiełczykowska, I. Musik, Anna Hordyjewska, A. Boguszewska, A. Lewandowska, K. Pasternak","doi":"10.2478/V10079-008-0013-3","DOIUrl":"https://doi.org/10.2478/V10079-008-0013-3","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132339824","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0009-Z
Jolanta Zdanowska-Filipczak, G. Orlicz-Szczęsna, W. Krupski
{"title":"Iodine influence on thyroid gland function","authors":"Jolanta Zdanowska-Filipczak, G. Orlicz-Szczęsna, W. Krupski","doi":"10.2478/V10079-008-0009-Z","DOIUrl":"https://doi.org/10.2478/V10079-008-0009-Z","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"120876866","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0007-1
B. Targońska-Stępniak, M. Majdan, M. Dryglewska, E. Kimak
{"title":"Effects of leflunomide therapy on the serum lipid profile in patients with rheumatoid arthritis","authors":"B. Targońska-Stępniak, M. Majdan, M. Dryglewska, E. Kimak","doi":"10.2478/V10079-008-0007-1","DOIUrl":"https://doi.org/10.2478/V10079-008-0007-1","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126561612","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0025-Z
Anna Gawęda
The C-reactive protein (CRP) is a constant component of the organism, it is present in blood serum in trace amounts of both healthy people and animals in physiological conditions (1, 2). Macrophage stimulation caused by tissue damage is a necessary condition for CRP synthesis (3, 4, 5). These cells produce pro-inflammatory cytokines which induce the expression of the APR gene. Interleukin 6 (IL-6) is the most important factor that stimulates CRP synthesis as well as all other acute phase proteins (5, 6). Interleukin 1 (IL-1) and tumor necrosis factor (TNF-a) stimulate macrophages, monocytes, fibroblasts, endothelium cells and others to produce IL-6 (6, 7, 8). CRP in the organism performs a defensive and reparative role (2, 3, 9, 10). This protein acts like an opsonin by joining with antigens and pathogen structure ligands and hastening their phagocytosis. CRP attaches to Fey receptors of human monocytes, neutrophils and other leucocytic system cells activating them. Cell stimulation results in a varied effector response, e.g. in the cytotoxic effect, phagocytosis, oxygen explosion or in the release of inflammatory mediators. C-reactive protein complexes with corresponding ligands activate the complement cascade mainly on the classical pathway (similarly to the antigen-antibody complexes). As a result of the
c -反应蛋白(CRP)是机体的恒定成分，在生理状态下，无论是健康人还是动物的血清中都存在微量的CRP(1,2)。组织损伤引起的巨噬细胞刺激是CRP合成的必要条件(3,4,5)。这些细胞产生促炎细胞因子，诱导APR基因的表达。白细胞介素6 (IL-6)是刺激CRP合成以及所有其他急性期蛋白的最重要因子(5,6)。白细胞介素1 (IL-1)和肿瘤坏死因子(TNF-a)刺激巨噬细胞、单核细胞、成纤维细胞、内皮细胞和其他细胞产生IL-6(6,7,8)。CRP在机体中发挥防御和修复作用(2,3,9,10)。这种蛋白质像调理素一样，与抗原和病原体结构配体结合，加速它们的吞噬。CRP附着在人单核细胞、中性粒细胞和其他激活它们的白细胞系统细胞的Fey受体上。细胞刺激导致各种效应反应，例如细胞毒性作用、吞噬作用、氧爆炸或炎症介质的释放。具有相应配体的c反应蛋白复合物主要通过经典途径激活补体级联(类似于抗原-抗体复合物)。作为结果
{"title":"The analysis of C-reactive concentration in patients with maxillofacial fractures","authors":"Anna Gawęda","doi":"10.2478/V10079-008-0025-Z","DOIUrl":"https://doi.org/10.2478/V10079-008-0025-Z","url":null,"abstract":"The C-reactive protein (CRP) is a constant component of the organism, it is present in blood serum in trace amounts of both healthy people and animals in physiological conditions (1, 2). Macrophage stimulation caused by tissue damage is a necessary condition for CRP synthesis (3, 4, 5). These cells produce pro-inflammatory cytokines which induce the expression of the APR gene. Interleukin 6 (IL-6) is the most important factor that stimulates CRP synthesis as well as all other acute phase proteins (5, 6). Interleukin 1 (IL-1) and tumor necrosis factor (TNF-a) stimulate macrophages, monocytes, fibroblasts, endothelium cells and others to produce IL-6 (6, 7, 8). CRP in the organism performs a defensive and reparative role (2, 3, 9, 10). This protein acts like an opsonin by joining with antigens and pathogen structure ligands and hastening their phagocytosis. CRP attaches to Fey receptors of human monocytes, neutrophils and other leucocytic system cells activating them. Cell stimulation results in a varied effector response, e.g. in the cytotoxic effect, phagocytosis, oxygen explosion or in the release of inflammatory mediators. C-reactive protein complexes with corresponding ligands activate the complement cascade mainly on the classical pathway (similarly to the antigen-antibody complexes). As a result of the","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129142442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0020-4
Elzbieta Osińska, Agnieszka Zwierzyk-Karlowska, K. Gromysz-Kałkowska
{"title":"The problem of tobacco smoking among the young people under the survey research. II. Grammar school students","authors":"Elzbieta Osińska, Agnieszka Zwierzyk-Karlowska, K. Gromysz-Kałkowska","doi":"10.2478/V10079-008-0020-4","DOIUrl":"https://doi.org/10.2478/V10079-008-0020-4","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126352877","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2008-06-01DOI: 10.2478/V10079-008-0030-2
B. Chmielewska, K. Rejdak, Z. Stelmasiak
{"title":"Epileptic seizures following an ischaemic hemispheric stroke","authors":"B. Chmielewska, K. Rejdak, Z. Stelmasiak","doi":"10.2478/V10079-008-0030-2","DOIUrl":"https://doi.org/10.2478/V10079-008-0030-2","url":null,"abstract":"","PeriodicalId":265816,"journal":{"name":"Annales Umcs, Medicina","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2008-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122270240","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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