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Long COVID: The Silent Pandemic 漫长的COVID:无声的大流行
Pub Date : 2023-06-15 DOI: 10.59541/001c.81031
Sarah Draud, Josue Prado, Trevor Hass, Julio Ramirez
Long COVID, a chronic condition affecting individuals who have recovered from the acute phase of COVID-19, has become a significant global challenge. This review article provides an overview of the latest literature on Long COVID, focusing on its epidemiology, natural history, definitions, clinical manifestations, pathophysiology, management, and prevention. Approximately 10 to 20% of individuals experience a wide range of persistent symptoms lasting for months to years. The lack of diagnostic tests and a standardized definition for Long COVID has led to underdiagnosis and disregard of the condition, turning it into a silent pandemic. The burden on public health and society is substantial, impacting individuals and communities across demographics and causing economic losses and socioeconomic issues. It affects people of all ages, including those without pre-existing conditions. Complex pathophysiology involves factors such as viral persistence, immune system abnormalities, dysregulated inflammatory response, dysbiosis, reactivation of other viruses, and microthrombi formation. These mechanisms contribute to the diverse range of varied multisystemic symptoms. Accurate diagnosis and appropriate management are crucial, as the condition can significantly impair quality of life. Management is based on a symptom-based approach and requires multidisciplinary care involving healthcare professionals from various specialties. Further research is needed to raise awareness, understand the natural history and prognosis, and develop effective treatment guidelines for this emerging healthcare burden. Staying informed on Long COVID research is vital for the efficient management of this public health crisis.
长冠肺炎是一种影响COVID-19急性期恢复期患者的慢性疾病,已成为一项重大的全球挑战。本文综述了新冠肺炎的流行病学、自然历史、定义、临床表现、病理生理、管理和预防等方面的最新文献。大约10%至20%的人会经历持续数月至数年的各种持续性症状。由于缺乏诊断测试和对长冠状病毒的标准化定义,导致诊断不足和对病情的忽视,使其成为一场无声的大流行。对公共卫生和社会的负担是巨大的,影响到各个人口群体的个人和社区,并造成经济损失和社会经济问题。它影响所有年龄段的人,包括那些没有预先存在疾病的人。复杂的病理生理包括病毒持续存在、免疫系统异常、炎症反应失调、生态失调、其他病毒的再激活和微血栓形成等因素。这些机制导致了多种多样的多系统症状。准确的诊断和适当的管理是至关重要的,因为这种情况会严重损害生活质量。管理是基于症状为基础的方法,需要多学科的护理涉及来自不同专业的医疗保健专业人员。需要进一步的研究来提高认识,了解自然历史和预后,并为这一新兴的医疗负担制定有效的治疗指南。及时了解COVID - 19长期研究对于有效管理这场公共卫生危机至关重要。
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引用次数: 0
Infection Prevention Education Simplified: The Pros and Cons of Using CDC’s Project Firstline 简化感染预防教育:使用疾控中心项目一线的利弊
Pub Date : 2023-06-12 DOI: 10.59541/001c.77921
Melissa Travis
Education is an important component of a successful infection prevention program. Although most infection preventionists recognize the need for education, there is limited time to devote to this endeavor. The Centers for Disease Control and Prevention released an educational program to help educate frontline healthcare workers about infection prevention principles. It can be a useful resource to meet the educational needs in a healthcare organization or facility; however, there are some barriers to using the program as written.
教育是一个成功的感染预防计划的重要组成部分。虽然大多数感染预防学家认识到教育的必要性,但投入这项努力的时间有限。美国疾病控制与预防中心发布了一项教育计划,帮助教育一线医护人员预防感染的原则。它可以是一个有用的资源,以满足医疗机构或设施的教育需求;然而,按照编写的程序使用有一些障碍。
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引用次数: 0
Conspiracy Theories and Ebola: Lessons Learned Important for Future Pandemics 阴谋论与埃博拉:对未来流行病的重要教训
Pub Date : 2023-06-12 DOI: 10.59541/001c.77445
S. Smallman
The public health campaign against Ebola in the Democratic Republic of the Congo faced serious challenges, some due to conspiracy theories and denial. These beliefs were so powerful that they even caused repeated attacks upon health care providers and medical centers. These conspiracy theories were nothing new, as they are a common feature of all frightening epidemics, such as HIV and COVID-19. These narratives also circulated during the 2015 West African Ebola outbreak. Addressing conspiracy theories during an epidemic requires a coordinated campaign involving not only local leaders but also the cooperation of social media organizations.
刚果民主共和国抗击埃博拉的公共卫生运动面临严峻挑战,其中一些挑战来自阴谋论和否认。这些信念是如此强大,以至于它们甚至导致了对卫生保健提供者和医疗中心的反复攻击。这些阴谋论并不新鲜,因为它们是所有可怕流行病(如艾滋病毒和COVID-19)的共同特征。这些说法在2015年西非埃博拉疫情期间也曾流传。在流行病期间解决阴谋论需要协调一致的运动,不仅涉及地方领导人,还涉及社交媒体组织的合作。
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引用次数: 0
High consistency between recommendations by a pulmonary specialist and ChatGPT for the management of a patient with non-resolving pneumonia 肺科专家和ChatGPT对非解决性肺炎患者管理的建议高度一致
Pub Date : 2023-05-17 DOI: 10.59541/001c.75456
A. Chirino, T. Wiemken, S. Furmanek, William A. Mattingly, T. Chandler, G. Cabral, R. Cavallazzi, R. Carrico, Julio A Ramirez
The use of artificial intelligence in healthcare is rapidly growing, with great potential to assist medical professionals in diagnosis and treatment of complex medical conditions. In this case report, the recommendations of a pulmonary consultation are compared to the recommendations from a large language model (LLM), ChatGPT, in regards to a case of non-resolving pneumonia. The recommendations by ChatGPT were found to be consistent with the pulmonary consultation, and no recommendations given were inappropriate. As shown in this case report, early generations of LLM such as ChatGPT were able to provide appropriate recommendations for the management of a patient with a complex medical condition.
人工智能在医疗保健领域的应用正在迅速增长,在协助医疗专业人员诊断和治疗复杂医疗状况方面具有巨大潜力。在本病例报告中,将肺部会诊的建议与大型语言模型(LLM) ChatGPT的建议进行比较,以解决一个非解决性肺炎病例。ChatGPT的建议与肺部会诊一致,没有不适当的建议。如本病例报告所示,早期的LLM(如ChatGPT)能够为复杂疾病患者的管理提供适当的建议。
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引用次数: 1
Letter from the Editor-in-Chief 总编辑来信
Pub Date : 2023-04-07 DOI: 10.59541/001c.74205
Julio A. Ramirez
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引用次数: 0
Nurses in a SNAP: Increasing Self-Confidence for Competent Nursing Practice through a Student Nurse Employment Model 护士在一个SNAP:通过学生护士就业模式提高自信胜任护理实践
Pub Date : 2023-01-16 DOI: 10.59541/001c.77923
Brittany Burke
Although self-confidence is strongly correlated with safe patient care, there is limited research about self-confidence perceptions among new graduate nurses upon entry into licensed practice. This study evaluated the effect of the Student Nurse Apprenticeship Program’s (SNAP) three-tiered employment model on new graduate registered nurse (RN) self-confidence and the organization’s subsequent return on investment. Evaluate the effect of a pre-licensure, student nurse employment model on licensed nurses in three areas: perceived self-confidence related to patient safety, new graduate nurse orientation length, and organizational RN retention. A quasi-experimental, nonequivalent control group posttest study was conducted at Norton Healthcare (NHC) with SNAP Cohort One. Graduate RNs who completed SNAP and a control group of non-SNAP new graduate RNs took the Health Professional Education in Patient Safety Survey tool prior to starting NHC new graduate nurse orientation. During SNAP application, applicants completed the Human Systems Integration tool which aids in assessment of the relationship between the individual and the role’s responsibilities. In SNAP Cohort One, statistically significant (p < 0.05) increases in perceived self-confidence related to patient safety were found in SNAP graduates. Organizational retention was captured at 90% from SNAP to NHC RN, a 94% one-year RN retention, and a 96% two-year RN retention. The mean new graduate RN orientation length for SNAP graduates decreased three weeks. Total organizational cost avoidance of $8.5 million was shown in decreased orientation time and first year RN retention. This study shows that the new graduate RNs completing SNAP had higher perceived self-confidence related to patient safety compared to new graduate RNs who did not complete SNAP. With the success of SNAP Cohort One, in conjunction with the strong return on NHC’s financial investment and creation of a workforce pipeline, NHC continued the program. After five successful cohorts and 696 student nurses, SNAP graduates avoided the organization over $33 million in first year RN turnover costs. SNAP graduate to NHC RN retention remained at 90%, with first year RN retention at 92%, and second year RN retention at 84%. The mean decrease in orientation time for all five cohorts remained between two and three weeks.
虽然自信与病人的安全护理密切相关,但关于新毕业护士进入执业许可后的自信认知的研究有限。本研究评估了学生护士学徒计划(SNAP)三层就业模式对新毕业注册护士(RN)自信心和组织后续投资回报的影响。评估预许可、学生护士就业模式在三个方面对持牌护士的影响:与患者安全相关的感知自信、新毕业护士入职时间和组织注册护士保留。在诺顿医疗保健(NHC)进行了一项准实验,非等效对照组后测研究,其中包括SNAP队列1。完成SNAP的毕业生注册护士和未完成SNAP的新毕业注册护士的对照组在开始NHC新毕业护士培训之前接受了患者安全调查工具中的卫生专业教育。在申请SNAP期间,申请人完成了人力系统集成工具,该工具有助于评估个人与角色职责之间的关系。在SNAP队列1中,SNAP毕业生与患者安全相关的感知自信增加有统计学意义(p < 0.05)。从SNAP到NHC注册护士的组织保留率为90%,一年注册护士保留率为94%,两年注册护士保留率为96%。SNAP毕业生的平均新毕业生注册护士培训时间缩短了三周。总组织成本避免为850万美元,体现在培训时间和第一年注册护士保留率的减少上。本研究表明,与未完成SNAP的新毕业生注册护士相比,完成SNAP的新毕业生注册护士对患者安全的感知自信更高。随着SNAP第一批项目的成功,加上国家健康中心财政投资的强劲回报和劳动力渠道的建立,国家健康中心继续实施了该项目。在五个成功的队列和696名学生护士之后,SNAP的毕业生避免了该组织第一年超过3300万美元的注册护士流动成本。SNAP毕业生到NHC的注册护士保留率保持在90%,第一年注册护士保留率为92%,第二年注册护士保留率为84%。所有五个队列的平均适应时间减少保持在两到三周之间。
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引用次数: 0
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