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The sound of anxiety: exploring the effect of audio recordings of breathing on self-reported breathlessness 焦虑的声音:探索呼吸录音对自我报告的呼吸困难的影响
Pub Date : 2021-09-05 DOI: 10.1183/13993003.congress-2021.oa165
N. Lovell, S. Etkind, Wendy Prentice, Irene J. Higginson, K. Sleeman
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引用次数: 1
Aerobic Training Improves Pulmonary and Systemic Inflammatory and Fibrotic Response in Asthmatics 有氧训练改善哮喘患者肺部和全身炎症和纤维化反应
Pub Date : 2021-09-05 DOI: 10.1183/13993003.congress-2021.oa2935
R. Moraes Ferreira, M. A. R. Brandao-Rangel, A. Silva-Reis, Thiago G Gibson-Alves, Helida C Aquino-Santos, Victor H Souza-Palmeira, Claudio R Frison, R. P. Vieira
{"title":"Aerobic Training Improves Pulmonary and Systemic Inflammatory and Fibrotic Response in Asthmatics","authors":"R. Moraes Ferreira, M. A. R. Brandao-Rangel, A. Silva-Reis, Thiago G Gibson-Alves, Helida C Aquino-Santos, Victor H Souza-Palmeira, Claudio R Frison, R. P. Vieira","doi":"10.1183/13993003.congress-2021.oa2935","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa2935","url":null,"abstract":"","PeriodicalId":275802,"journal":{"name":"Rehabilitation and chronic care","volume":"90 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132220352","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effects of a NMES program in exercise capacity of hospitalized severely hypoxemic COPD patients NMES计划对住院严重低氧COPD患者运动能力的影响
Pub Date : 2021-09-05 DOI: 10.1183/13993003.congress-2021.pa317
A. Calvache Mateo, L. Lopez Lopez, Janet Remedios Rodríguez Torres, I. Torres Sánchez, María Granados Santiago, A. Conde Valero, M. Valenza
{"title":"Effects of a NMES program in exercise capacity of hospitalized severely hypoxemic COPD patients","authors":"A. Calvache Mateo, L. Lopez Lopez, Janet Remedios Rodríguez Torres, I. Torres Sánchez, María Granados Santiago, A. Conde Valero, M. Valenza","doi":"10.1183/13993003.congress-2021.pa317","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.pa317","url":null,"abstract":"","PeriodicalId":275802,"journal":{"name":"Rehabilitation and chronic care","volume":"100 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130328911","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Effectiveness of multi-disciplinary community respiratory team management of chronic respiratory illness during the COVID-19 pandemic COVID-19大流行期间慢性呼吸道疾病多学科社区呼吸团队管理效果分析
Pub Date : 2021-09-05 DOI: 10.1183/13993003.congress-2021.oa2938
Emma Johnson, Emily Turner, S. Gingles, K. Levin, Elaine Mackay, C. Roux, M. Milligan, Marion Mackie, Kirsten Farrell, K. Murray, S. Adams, J. Brand, H. Bayes, David F. Anderson
{"title":"Effectiveness of multi-disciplinary community respiratory team management of chronic respiratory illness during the COVID-19 pandemic","authors":"Emma Johnson, Emily Turner, S. Gingles, K. Levin, Elaine Mackay, C. Roux, M. Milligan, Marion Mackie, Kirsten Farrell, K. Murray, S. Adams, J. Brand, H. Bayes, David F. Anderson","doi":"10.1183/13993003.congress-2021.oa2938","DOIUrl":"https://doi.org/10.1183/13993003.congress-2021.oa2938","url":null,"abstract":"","PeriodicalId":275802,"journal":{"name":"Rehabilitation and chronic care","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2021-09-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129412311","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
What should Pulmonary Rehabilitation (PR) look like for adults living with post-TB lung disease (PTBLD) in Kyrgyzstan? A qualitative study 吉尔吉斯斯坦成人结核后肺病(PTBLD)患者的肺部康复(PR)应该是什么样的?定性研究
Pub Date : 2021-09-05 DOI: 10.1183/13993003.congress-2021.pa1986
G. Mirzalieva, M. Mademilov, Zainab K Yusuf, M. Orme, C. Bourne, A. Jones, Ruhme B. Miah, A. Akylbekov, Rupert C Jones, A. Barton, D. Malcolm, T. Sooronbaev, Sally J. Singh
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引用次数: 1
Internet access and usage in patients with chronic respiratory disease 慢性呼吸道疾病患者的互联网接入和使用
Pub Date : 2020-09-07 DOI: 10.1183/13993003.congress-2020.84
O. Polgar, C. Nolan, R. Barker, S. Patel, J. Walsh, W. Man
Background: Digital technologies provide an opportunity to support the health needs of people living with chronic respiratory disease (CRD). However, there is limited information on digital literacy levels. Aim: To determine day-to-day use of the internet in patients with CRD. Method: A survey of consecutive outpatients attending a general respiratory clinic. Patients with COPD, asthma, bronchiectasis or interstitial lung disease were included. Results: Demographic characteristics: 57 women:40 men; mean age 72.9 (±8.6); 74% with COPD. Most of those surveyed had access to a mobile phone (86%) used primarily for calls and texting; only 8% used their phone to access the internet. Access to other digital devices were more heterogeneous (tablet 31%, laptop 29%, PC 16%). 53% reported feeling not confident or needing help with accessing the internet. 49% accessed the internet daily, primarily to read the news (28%) or use email (26%). Only 10% said they used the internet to access healthcare information. Age and sex were not associated with confidence or frequency of internet use (Figure 1). Conclusion: There is wide variability in accessibility and confidence in using the internet in people with chronic respiratory disease. This needs to be taken into account when designing digital health interventions for this patient group.
背景:数字技术为支持慢性呼吸道疾病(CRD)患者的健康需求提供了机会。然而,关于数字素养水平的信息有限。目的:确定CRD患者的日常互联网使用情况。方法:对某呼吸内科门诊连续就诊的患者进行调查。包括COPD、哮喘、支气管扩张或间质性肺疾病患者。结果:人口统计学特征:女性57例,男性40例;平均年龄72.9(±8.6)岁;74%患有慢性阻塞性肺病。大多数受访者(86%)使用手机,主要用于打电话和发短信;只有8%的人使用手机上网。对其他数字设备的访问更加多样化(平板电脑31%,笔记本电脑29%,PC 16%)。53%的人表示对上网感到不自信或需要帮助。49%的人每天上网,主要是阅读新闻(28%)或使用电子邮件(26%)。只有10%的人表示他们使用互联网获取医疗信息。年龄和性别与互联网使用的信心或频率无关(图1)。结论:慢性呼吸道疾病患者在使用互联网的可及性和信心方面存在很大差异。在为这一患者群体设计数字卫生干预措施时,需要考虑到这一点。
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引用次数: 0
Late Breaking Abstract - The weekly recovery of physical capacities in COVID-19 patients during post-extubation pulmonary rehabilitation 摘要- COVID-19患者拔管后肺部康复期间每周体能恢复情况
Pub Date : 2020-09-07 DOI: 10.1183/13993003.congress-2020.938
Yara Al Chikhanie, S. Vergès, F. Hérengt, D. Veale
Some COVID-19 patients develop a severe form of the disease requiring intubation and admission to the intensive care unit (ICU). We aim to evaluate the recovery of the walking ability during pulmonary rehabilitation (PR) post-extubation. We evaluated patients with severe COVID-19 during PR using weekly six-minute walking tests. We measured the walking distance (6MWD), oxygen saturation (SpO2) and dyspnea. 17 COVID-19 patients (10 male, 7 female) with an average age of 70±11 years old were admitted to the Dieulefit Sante PR center. All had at least one of the following comorbidities: cardiovascular, COPD, diabetes or cancer, and mean BMI was 27±6 Kg/m2. On average, they spent 22±7 days in ICU and 12±8 days in the pulmonary ward before enrolling in PR. This graph shows the weekly 6MWD evolution. On average, PR lasted 21±8 days, 6MWD increased from 16±16% to 43±21% of theoretical values. A strong negative correlation existed between the number of days post-extubation before PR, and the gain in 6MWD. Patients showed severe desaturation (SpO2 nadir 85±5 %) despite oxygen supply (4±1 L/min) but modest dyspnea (4±2). Patients had a significant recovery early post-extubation but left PR with a significant impairment in 6MWD. Patients who spent less time bedridden between ICU and PR, recovered faster. These results show the importance of PR in patients post COVID-19, the sooner and the longer, the better.
一些COVID-19患者发展为严重形式的疾病,需要插管并进入重症监护病房(ICU)。我们的目的是评估肺康复(PR)拔管后行走能力的恢复情况。我们通过每周6分钟步行测试评估PR期间严重COVID-19患者。测量步行距离(6MWD)、血氧饱和度(SpO2)和呼吸困难。dieeulefit Sante PR中心收治的新冠肺炎患者17例(男10例,女7例),平均年龄70±11岁。所有患者至少有以下合并症之一:心血管、慢性阻塞性肺病、糖尿病或癌症,平均BMI为27±6 Kg/m2。在PR入组前,他们在ICU平均住院22±7天,在肺病房平均住院12±8天。该图显示了每周6MWD的演变。平均PR持续21±8天,6MWD由理论值的16±16%增加到43±21%。拔管后PR前的天数与6MWD的增加之间存在很强的负相关。尽管供氧(4±1 L/min),患者仍出现严重的去饱和(SpO2最低点85±5%),但中度呼吸困难(4±2)。患者拔管后早期恢复明显,但离开PR时6MWD明显受损。在ICU和PR之间卧床时间较短的患者恢复得更快。这些结果表明PR在COVID-19后患者中的重要性,越早越长越好。
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引用次数: 1
Implication of regular pulmonary function evaluation in Duchenne muscular dystrophy 杜氏肌营养不良患者定期肺功能评估的意义
Pub Date : 2020-06-19 DOI: 10.21203/rs.3.rs-36561/v1
J. Lee, Seong-Woong Kang, Eun Young Kim, W. Choi
BackgroundVarious factors are considered when determining the need to initiate noninvasive ventilation (NIV), for example hypoventilatory symptoms, forced vital capacity (FVC), maximal inspiratory pressure (MIP), and end-tidal carbon dioxide. We aim to reveal the clinical importance of regular pulmonary function evaluation before the initiation of NIV by comparing Duchenne muscular dystrophy (DMD) patients with and without regular medical surveillance.MethodsThis retrospective study analyzes successful applications of NIV in our pulmonary rehabilitation center. We assigned 200 DMD patients, hospitalized between June 2006 and August 2019, to one of two groups, according to their follow-up status before NIV initiation. Group 1 (n = 102) had been followed-up regularly via the outpatient clinic at least twice a year. Group 2 (n = 98) was hypercapnic, either at the first visit, or re-visit after having missed the outpatient clinic appointment for more than one year.ResultsSignificantly more patients were admitted via emergency room in group 2 (2.0% in group 1 and 28.6% in group 2). The patients’ age was higher in group 2 (18.3 ± 3.7 years in group and 21.2 ± 4.8 years in group 2). Ventilatory status evaluated by arterial blood gas analysis and transcutaneous continuous monitoring was better in group 1 than that of group 2. And all measures of pulmonary function, including FVC, peak cough flow, MIP, maximal expiratory pressure, and ventilatory status, were superior in group 1, too.ConclusionsRegular follow-up before the onset of ventilatory insufficiency is crucial for the timely application of NIV, and appropriate NIV can exert a preventive effect on respiratory function deterioration.
背景:在确定是否需要启动无创通气(NIV)时,需要考虑各种因素,例如低通气症状、用力肺活量(FVC)、最大吸气压力(MIP)和潮末二氧化碳。我们的目的是通过比较有和没有定期医学监测的杜氏肌营养不良症(DMD)患者,揭示在NIV开始前定期肺功能评估的临床重要性。方法回顾性分析无创通气在肺康复中心的成功应用情况。我们将2006年6月至2019年8月期间住院的200名DMD患者根据其开始使用NIV前的随访情况分为两组。第1组102例患者每年至少进行两次门诊随访。第2组(n = 98)是高碳酸血症,无论是在第一次就诊时,还是错过门诊预约超过一年后再次就诊。结果2组经急诊就诊的患者明显多于2组(2组为28.6%,2组为2.0%),2组患者年龄明显高于2组(2组为21.2±4.8岁,1组为18.3±3.7岁),1组动脉血气分析及经皮连续监测通气状况优于2组。所有肺功能指标,包括FVC、咳嗽峰值流量、MIP、最大呼气压和通气状态,组1也优于对照组。结论通气功能不全发生前的定期随访是及时使用无创通气设备的关键,合适的无创通气设备可对呼吸功能恶化起到预防作用。
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引用次数: 0
Increased Myostatin as a Negative Regulator of Muscle Regeneration Potential in Sarcopenic COPD Patients: Clinical Implications 肌萎缩性慢阻肺患者肌肉再生潜能负调节肌生长抑制素增加:临床意义
Pub Date : 2020-05-01 DOI: 10.1164/ajrccm-conference.2020.201.1_meetingabstracts.a7541
Antonio Sancho Muñoz, M. Guitart, D. Rodriguez, J. Gea, Juana Martínez Llorens, Esther Barreiro Portela
Whether a deficiency in muscle repair and regeneration may exist in the lower limb muscles of COPD patients remains debatable. We hypothesized that the negative regulator myotastin may inhibit muscle regeneration potential in sarcopenic COPD patients. In vastus lateralis (VL) of control subjects and severe COPD patients with and without sarcopenia, satellite cells (SC) were identified (immunofluorescence, anti-Pax7 and anti-myf5): activated (Pax7+ and myf5+), quiescent/regenerative potential (Pax7+ and myf-5-), and total SC, nuclear activation (TUNEL assay), and muscle fiber type (morphometry, hybrid fibers), muscle damage, muscle regeneration markers (Pax7, myf-5, myogenin, and myoD), and myostatin levels were identified. Compared to control subjects and normal body composition COPD, in the VL of sarcopenic COPD patients, myostatin protein levels, activated SC, hybrid fibers, TUNEL-positive cells, internal nuclei, and total abnormal fraction were significantly increased, while quadriceps muscle strength, numbers of Pax7+ and myf-5- and slow- and fast-twitch muscle fiber areas decreased. In VL of sarcopenic and non-sarcopenic COPD patients, TUNEL-positive cell counts were greater, whereas expression of muscle regeneration markers was lower than in controls. Myostatin may have interfered with the process of muscle cell proliferation early on during the regeneration process, thus leading to poor muscle growth and development following injury in COPD patients with sarcopenia. This may be another relevant mechanism of muscle mass loss in COPD. Method: CIBERES, FIS 18/00075 (FEDER), SEPAR 2018, and unrestricted grant from Menarini SA 2018.
慢性阻塞性肺病患者下肢肌肉是否存在肌肉修复和再生缺陷仍有争议。我们假设负调节肌变抑素可能抑制肌肉减少性COPD患者的肌肉再生潜能。在对照受试者和伴有或不伴有肌肉减少症的严重COPD患者的股外侧肌(VL)中,鉴定卫星细胞(SC)(免疫荧光、抗Pax7和抗myf5):激活(Pax7+和myf5+)、静止/再生潜能(Pax7+和myf-5-)、总SC、核激活(TUNEL测定)、肌纤维类型(形态测定、杂交纤维)、肌肉损伤、肌肉再生标志物(Pax7、myf-5、肌原素和myoD)和肌肉生长抑制素水平。与对照组和正常体成分COPD患者相比,肌肉减少性COPD患者VL中肌肉生长抑制素蛋白水平、活化SC、杂交纤维、tunel阳性细胞、内核和总异常分数显著增加,股四头肌肌力、Pax7+和myf-5以及慢、快肌纤维区数量减少。在肌肉减少和非肌肉减少的COPD患者的VL中,tunel阳性细胞计数更高,而肌肉再生标志物的表达低于对照组。肌肉生长抑制素可能在再生过程的早期干扰了肌肉细胞的增殖过程,从而导致COPD患者肌肉减少症损伤后肌肉生长发育不良。这可能是COPD患者肌肉质量减少的另一个相关机制。方法:CIBERES, FIS 18/00075 (FEDER), SEPAR 2018,以及Menarini SA 2018的无限制资助。
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引用次数: 2
Heterogeneity of Danish lung choirs and their singing leaders – a study of performance, experiences, and attitudes in an emerging field 丹麦肺唱诗班和他们的歌唱领袖的异质性-在一个新兴领域的表现,经验和态度的研究
Pub Date : 2019-11-21 DOI: 10.1183/13993003.congress-2019.pa3957
M. Kaasgaard, I. Andersen, P. Vuust, O. Hilberg, A. Loekke, Uffe Boedtger
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引用次数: 0
期刊
Rehabilitation and chronic care
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