Pub Date : 2022-07-17DOI: 10.52338/cicasrep.2022.1003
Shivangi Patel, O. Qazi, Shuan Li, M. Madruga
We have a 57 year old female with past medical history significant only for hypothyroidism and generalized lymphadenopathy who presents with acute behavioral changes. She was minimally responsive on exam, nonverbal, and only weakly able to follow basic commands such as squeezing her hands. Her physical exam was notable for scarring of bilateral eyebrows (figures 1 and 2), which occurred three years ago when she had cosmetic tattooing of her eyebrows. She was accompanied by her husband who states that she does not take any medications at home other than levothyroxine. Clinical testing including neuroimaging with CT and MRI, EEG, CBC/CMP, TSH, HIV, RPR, urine drug screen, and CSF analysis were all normal. On a previous admission, patient had a full-body CT performed which showed extensive lymphadenopathy throughout the neck, bilateral hila, mesentery, and retroperitoneum.
{"title":"Koebner Phenomenon: a Clinical Clue of Systemic Sarcoidosis","authors":"Shivangi Patel, O. Qazi, Shuan Li, M. Madruga","doi":"10.52338/cicasrep.2022.1003","DOIUrl":"https://doi.org/10.52338/cicasrep.2022.1003","url":null,"abstract":"We have a 57 year old female with past medical history significant only for hypothyroidism and generalized lymphadenopathy who presents with acute behavioral changes. She was minimally responsive on exam, nonverbal, and only weakly able to follow basic commands such as squeezing her hands. Her physical exam was notable for scarring of bilateral eyebrows (figures 1 and 2), which occurred three years ago when she had cosmetic tattooing of her eyebrows. She was accompanied by her husband who states that she does not take any medications at home other than levothyroxine. Clinical testing including neuroimaging with CT and MRI, EEG, CBC/CMP, TSH, HIV, RPR, urine drug screen, and CSF analysis were all normal. On a previous admission, patient had a full-body CT performed which showed extensive lymphadenopathy throughout the neck, bilateral hila, mesentery, and retroperitoneum.","PeriodicalId":279597,"journal":{"name":"Clinical Imaging and Case Reports","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127399961","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2022-07-10DOI: 10.52338/cicasrep.2022.1004
Gokhan Dogukan Akarsu, R. Akarsu
This study is a systematic review and was prepared according to the PRISMA checklist and Cochrane guide. Science Direct, Web of Science, SCOPUS, Springer Link, Networked Digital Library of Theses & Dissertations, Ovid, CINAHL, Pubmed, Cochrane Library, using the Proquest database “Alzheimer Disease”, “Alzheimer”, “A.D”., “Thymoquinone” , “TQ”, “Nigella Sativa”, “NS” etc. Search was made using keywords. The abstracts of 251 theses, which were scanned between March and April 2022 and constitute the universe, were systematically examined and 18 articles suitable for the purpose of the research formed the sample of the research.
本研究是一项系统综述，根据PRISMA检查表和Cochrane指南进行准备。Science Direct, Web of Science, SCOPUS, Springer Link，网络数字论文库，Ovid, CINAHL, Pubmed, Cochrane Library，使用Proquest数据库“Alzheimer Disease”，“Alzheimer”，“ad”。、“百里醌”、“TQ”、“黑草”、“NS”等。使用关键字进行搜索。对构成宇宙的2022年3月至4月扫描的251篇论文的摘要进行系统审查，选出符合研究目的的18篇文章作为研究样本。
{"title":"EFFECTIVENESS OF THYMOKINO IN ALZHEIMER’S DISEASE: A SYSTEMATIC REVIEW IN RAT MODELS","authors":"Gokhan Dogukan Akarsu, R. Akarsu","doi":"10.52338/cicasrep.2022.1004","DOIUrl":"https://doi.org/10.52338/cicasrep.2022.1004","url":null,"abstract":"This study is a systematic review and was prepared according to the PRISMA checklist and Cochrane guide. Science Direct, Web of Science, SCOPUS, Springer Link, Networked Digital Library of Theses & Dissertations, Ovid, CINAHL, Pubmed, Cochrane Library, using the Proquest database “Alzheimer Disease”, “Alzheimer”, “A.D”., “Thymoquinone” , “TQ”, “Nigella Sativa”, “NS” etc. Search was made using keywords. The abstracts of 251 theses, which were scanned between March and April 2022 and constitute the universe, were systematically examined and 18 articles suitable for the purpose of the research formed the sample of the research.","PeriodicalId":279597,"journal":{"name":"Clinical Imaging and Case Reports","volume":"12 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-10","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127731813","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Accurate discrimination between high grade gliomas (HGG) and metastatic brain tumor (MET) using noninvasive imaging is essential for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.
{"title":"Texture analysis of quantitative ADC maps to differentiate low from high grade glioma","authors":"Shesnia Salim Padikkalakandy Cheriyath, Rishal Reshin Brayin Pokkantakath","doi":"10.52338/cicasrep.2022.1002","DOIUrl":"https://doi.org/10.52338/cicasrep.2022.1002","url":null,"abstract":"Accurate discrimination between high grade gliomas (HGG) and metastatic brain tumor (MET) using noninvasive imaging is essential for selecting appropriate surgical and radiotherapy treatments and for determining the treatment response.","PeriodicalId":279597,"journal":{"name":"Clinical Imaging and Case Reports","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-04-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130505952","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-01-03DOI: 10.52338/cicasrep.2021.1001
S. Kawakami, Y. Fukuzawa, Hiroyuki Ichikawa, Takaharu Ide, K. Yorozu, K. Sakabe
It was confirmed that NMN causes a decrease in breast cancer cells. Breast cancer is now a major problem for women because it is sensitive to estrogen. The standard treatments for breast cancer are generally surgery, anticancer drugs, and radiation therapy. In addition, as a complementary / alternative therapy, it is said that stress management, relaxation for stress re-duction, vitamins, and dietary fiber, which are said to have antioxidant effects as nutritional components, are used. However, although there is potential from an antioxidant perspective at this stage, no evidence is available at this time. Therefore, this time, this research group investi-gated the effect on breast cancer cells at the in vitro level using the component “NMN”, which is currently attracting attention. When NMN was added to breast cancer cells, a significant rereduc- tion in breast cancer cells was observed in a concentration- dependent manner. Therefore, this time, we investigated α-ketoglutaric acid, NAD +, and AMPK, which are thought to be related to the anticancer effect. It was found that NMN has the effect of activating these, suggesting that NMN may be used as a complementary / alternative therapy for breast cancer patients in the fu-ture
{"title":"Anticancer action by natural ingredient NMN and its mechanism: Focusing on the molecular mechanism of NMN on breast cancer cells.","authors":"S. Kawakami, Y. Fukuzawa, Hiroyuki Ichikawa, Takaharu Ide, K. Yorozu, K. Sakabe","doi":"10.52338/cicasrep.2021.1001","DOIUrl":"https://doi.org/10.52338/cicasrep.2021.1001","url":null,"abstract":"It was confirmed that NMN causes a decrease in breast cancer cells. Breast cancer is now a major problem for women because it is sensitive to estrogen. The standard treatments for breast cancer are generally surgery, anticancer drugs, and radiation therapy. In addition, as a complementary / alternative therapy, it is said that stress management, relaxation for stress re-duction, vitamins, and dietary fiber, which are said to have antioxidant effects as nutritional components, are used. However, although there is potential from an antioxidant perspective at this stage, no evidence is available at this time. Therefore, this time, this research group investi-gated the effect on breast cancer cells at the in vitro level using the component “NMN”, which is currently attracting attention. When NMN was added to breast cancer cells, a significant rereduc- tion in breast cancer cells was observed in a concentration- dependent manner. Therefore, this time, we investigated α-ketoglutaric acid, NAD +, and AMPK, which are thought to be related to the anticancer effect. It was found that NMN has the effect of activating these, suggesting that NMN may be used as a complementary / alternative therapy for breast cancer patients in the fu-ture","PeriodicalId":279597,"journal":{"name":"Clinical Imaging and Case Reports","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-01-03","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"117255228","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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