Pub Date : 2017-06-22DOI: 10.1109/EMBC.2015.7319875
A. Balomenos, P. Tsakanikas, E. Manolakos
Cell tracking enables data extraction from timelapse “cell movies” and promotes modeling biological processes at the single-cell level. We introduce a new fully automated computational strategy to track accurately cells across frames in time-lapse movies. Our method is based on a dynamic neighborhoods formation and matching approach, inspired by motion estimation algorithms for video compression. Moreover, it exploits “divide and conquer” opportunities to solve effectively the challenging cells tracking problem in overcrowded bacterial colonies. Using cell movies generated by different labs we demonstrate that the accuracy of the proposed method remains very high (exceeds 97%) even when analyzing large overcrowded microbial colonies.
{"title":"Tracking single-cells in overcrowded bacterial colonies","authors":"A. Balomenos, P. Tsakanikas, E. Manolakos","doi":"10.1109/EMBC.2015.7319875","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7319875","url":null,"abstract":"Cell tracking enables data extraction from timelapse “cell movies” and promotes modeling biological processes at the single-cell level. We introduce a new fully automated computational strategy to track accurately cells across frames in time-lapse movies. Our method is based on a dynamic neighborhoods formation and matching approach, inspired by motion estimation algorithms for video compression. Moreover, it exploits “divide and conquer” opportunities to solve effectively the challenging cells tracking problem in overcrowded bacterial colonies. Using cell movies generated by different labs we demonstrate that the accuracy of the proposed method remains very high (exceeds 97%) even when analyzing large overcrowded microbial colonies.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2017-06-22","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116457243","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-09DOI: 10.1109/EMBC.2015.7320018
Zhiyu Huo, Joseph Griffin, Ryan Babiuch, Aaron D. Gray, Brad W. Willis, Skubic Marjorie, Shining Sun
We describe a feasibility study in which the Microsoft Kinect is used for a game-based exercise to strengthen posterior chain muscles which are often weak in those at high risk of anterior cruciate ligament (ACL) injury. In the game, subjects perform a single posterior chain strengthening exercise. The game uses a side-scrolling video display driven by a hip abduction exercise while a player lies down on the floor. Leg lifts beyond a predetermined angle trigger the jumping action of an animated tiger. We describe the scene and game control, which uses depth images from the Kinect. Although Kinect-based skeletal data are used for many games, the skeletal model does not yield good estimates for positions on the floor. Our proposed system uses multiple leg angle estimators for different angle regions to recognize the player lying down and capture the angle between two legs. We conducted an experiment that validates our system with marker-based Vicon ground truth data. We also present results of an end-to-end test using the game, showing feasibility.
{"title":"Examining the feasibility of a Microsoft Kinect ™ based game intervention for individuals with anterior cruciate ligament injury risk","authors":"Zhiyu Huo, Joseph Griffin, Ryan Babiuch, Aaron D. Gray, Brad W. Willis, Skubic Marjorie, Shining Sun","doi":"10.1109/EMBC.2015.7320018","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7320018","url":null,"abstract":"We describe a feasibility study in which the Microsoft Kinect is used for a game-based exercise to strengthen posterior chain muscles which are often weak in those at high risk of anterior cruciate ligament (ACL) injury. In the game, subjects perform a single posterior chain strengthening exercise. The game uses a side-scrolling video display driven by a hip abduction exercise while a player lies down on the floor. Leg lifts beyond a predetermined angle trigger the jumping action of an animated tiger. We describe the scene and game control, which uses depth images from the Kinect. Although Kinect-based skeletal data are used for many games, the skeletal model does not yield good estimates for positions on the floor. Our proposed system uses multiple leg angle estimators for different angle regions to recognize the player lying down and capture the angle between two legs. We conducted an experiment that validates our system with marker-based Vicon ground truth data. We also present results of an end-to-end test using the game, showing feasibility.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128585092","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7319452
P. Massobrio, Valentina Pasquale, S. Martinoia
In vitro neuronal networks coupled to Micro-Electrode Arrays (MEAs) represent a valid experimental framework to study neuronal dynamics. This preparation is free of chemical or physical constraints and allows neurons to self-organize during development, creating networks that exhibit complex spatio-temporal patterns of activity. Starting from this experimental evidence, here we address the question whether a particular network architecture can drive the network dynamics towards a sub-, super-, or critical state.
{"title":"Emergence of critical dynamics in large-scale in vitro cortical networks","authors":"P. Massobrio, Valentina Pasquale, S. Martinoia","doi":"10.1109/EMBC.2015.7319452","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7319452","url":null,"abstract":"In vitro neuronal networks coupled to Micro-Electrode Arrays (MEAs) represent a valid experimental framework to study neuronal dynamics. This preparation is free of chemical or physical constraints and allows neurons to self-organize during development, creating networks that exhibit complex spatio-temporal patterns of activity. Starting from this experimental evidence, here we address the question whether a particular network architecture can drive the network dynamics towards a sub-, super-, or critical state.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"5 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115319442","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7320131
A. Y. Zhou, Tom J. Zajdel, Michaela A. Teravest, M. Maharbiz
We present a miniaturized, free-floating monitoring system which makes use of electron transfer in Shewanella oneidensis sequestered behind a permeable membrane while maintaining diffusive contact with the environment, allowing for sensing environmental conditions. The system makes use of a commercial off-the-shelf (COTS) integrated circuit (IC) which sets a potential between a working electrode and a Ag/AgCl reference electrode while recording the resulting current from the electroactive cells. We successfully sensed both pyruvate and the environmental presence of E. coli via changes in the currents sensed. This work will enable the development of mobile aquatic sensing systems which make use of bacterial electron transfer as a transduction method. Further miniaturization of the recording mote, electrodes, packaging, and system is discussed.
{"title":"A miniaturized monitoring system for electrochemical biosensing using Shewanella oneidensis in environmental applications","authors":"A. Y. Zhou, Tom J. Zajdel, Michaela A. Teravest, M. Maharbiz","doi":"10.1109/EMBC.2015.7320131","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7320131","url":null,"abstract":"We present a miniaturized, free-floating monitoring system which makes use of electron transfer in Shewanella oneidensis sequestered behind a permeable membrane while maintaining diffusive contact with the environment, allowing for sensing environmental conditions. The system makes use of a commercial off-the-shelf (COTS) integrated circuit (IC) which sets a potential between a working electrode and a Ag/AgCl reference electrode while recording the resulting current from the electroactive cells. We successfully sensed both pyruvate and the environmental presence of E. coli via changes in the currents sensed. This work will enable the development of mobile aquatic sensing systems which make use of bacterial electron transfer as a transduction method. Further miniaturization of the recording mote, electrodes, packaging, and system is discussed.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"126 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115641246","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7319777
Tobias Cibis, B. Groh, Heike Gatermann, Heike Leutheuser, B. Eskofier
Medical diagnosis is the first level for recognition and treatment of diseases. To realize fast diagnosis, we propose a concept of a basic framework for the underwater monitoring of a diver's ECG signal, including an alert system that warns the diver of predefined medical emergency situations. The framework contains QRS detection, heart rate calculation and an alert system. After performing a predefined study protocol, the algorithm's accuracy was evaluated with 10 subjects in a dry environment and with 5 subjects in an underwater environment. The results showed that, in 3 out of 5 dives as well as in dry environment, data transmission remained stable. In these cases, the subjects were able to trigger the alert system. The evaluated data showed a clear ECG signal with a QRS detection accuracy of 90 %. Thus, the proposed framework has the potential to detect and to warn of health risks. Further developments of this sample concept can imply an extension for monitoring different biomedical parameters.
{"title":"Wearable real-time ecg monitoring with emergency alert system for scuba diving","authors":"Tobias Cibis, B. Groh, Heike Gatermann, Heike Leutheuser, B. Eskofier","doi":"10.1109/EMBC.2015.7319777","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7319777","url":null,"abstract":"Medical diagnosis is the first level for recognition and treatment of diseases. To realize fast diagnosis, we propose a concept of a basic framework for the underwater monitoring of a diver's ECG signal, including an alert system that warns the diver of predefined medical emergency situations. The framework contains QRS detection, heart rate calculation and an alert system. After performing a predefined study protocol, the algorithm's accuracy was evaluated with 10 subjects in a dry environment and with 5 subjects in an underwater environment. The results showed that, in 3 out of 5 dives as well as in dry environment, data transmission remained stable. In these cases, the subjects were able to trigger the alert system. The evaluated data showed a clear ECG signal with a QRS detection accuracy of 90 %. Thus, the proposed framework has the potential to detect and to warn of health risks. Further developments of this sample concept can imply an extension for monitoring different biomedical parameters.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123039374","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7319959
Arika Fukushima, T. Paul, Ryusei Shingaki, Takashi Koiso, Shinya Umeno, Ken Ueno
DNA microarray is used to determine the genotypes of several hundred thousand to several million SNPs (Single Nucleotide Polymorphisms) on multiple samples at a time. In the conventional method of genotyping using DNA microarray, it is assumed that each SNP has three types of genotypes: two homozygous and one heterozygous genotypes. However, in an ethnically homogeneous population, there are cases when all the samples of a SNP belong to one homozygous genotype, and there are some other cases, especially in the SNPs of low MAFs (Minor Allele Frequencies), each sample belongs to either of the two genotypes: one homozygous and one heterozygous genotypes. In those cases, the conventional method of genotyping may fail to properly determine the genotypes of the samples. In this paper, we propose a new genotyping method, which can be used as a post-processing technique of the conventional genotyping method, for re-judgment of the SNPs having one or two types of genotypes. The proposed method takes fluctuations of the fluorescence intensities of the signals of DNA microarray into account, assigns genotypes to samples from those genotype patterns that may occur under natural mating conditions and applies different genotype judgment methods depending on the number of genotype clusters of a SNP. We evaluate our proposed method using the data of 1000 Genome Project and have found that our proposed method is able to improve the genotyping performance of the conventional method.
{"title":"A proposal for improvement of genotyping performance for ethnically homogeneous population using DNA microarray","authors":"Arika Fukushima, T. Paul, Ryusei Shingaki, Takashi Koiso, Shinya Umeno, Ken Ueno","doi":"10.1109/EMBC.2015.7319959","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7319959","url":null,"abstract":"DNA microarray is used to determine the genotypes of several hundred thousand to several million SNPs (Single Nucleotide Polymorphisms) on multiple samples at a time. In the conventional method of genotyping using DNA microarray, it is assumed that each SNP has three types of genotypes: two homozygous and one heterozygous genotypes. However, in an ethnically homogeneous population, there are cases when all the samples of a SNP belong to one homozygous genotype, and there are some other cases, especially in the SNPs of low MAFs (Minor Allele Frequencies), each sample belongs to either of the two genotypes: one homozygous and one heterozygous genotypes. In those cases, the conventional method of genotyping may fail to properly determine the genotypes of the samples. In this paper, we propose a new genotyping method, which can be used as a post-processing technique of the conventional genotyping method, for re-judgment of the SNPs having one or two types of genotypes. The proposed method takes fluctuations of the fluorescence intensities of the signals of DNA microarray into account, assigns genotypes to samples from those genotype patterns that may occur under natural mating conditions and applies different genotype judgment methods depending on the number of genotype clusters of a SNP. We evaluate our proposed method using the data of 1000 Genome Project and have found that our proposed method is able to improve the genotyping performance of the conventional method.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"450 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123052501","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7318748
G. Karanasiou, Dimitrios A. Gatsios, M. Lykissas, K. Stefanou, G. Rigas, I. Lagaris, Ioannis P. Kostas-Agnantis, I. Gkiatas, A. Beris, D. Fotiadis
Microanastomosis is a surgical procedure used to reconnect two blood vessels using sutures. The optimal microanastomosis may be predicted by assessing the factors that influence this invasive procedure. Blood flow and hemodynamics following microanastomosis are important factors for the successful longevity of this operation. How is the blood flow affected by the presence of sutures? Computational Fluid Dynamics (CFD) is a powerful tool that permits the estimation of specific quantities, such as fluid stresses, that are hardly measurable in vivo. In this study, we propose a methodology which evaluates the alterations in the hemodynamic status due to microanastomosis. A CFD model of a reconstructed artery has been developed, based on anatomical information provided by intravascular ultrasound and angiography, and was used to simulate blood flow after microanastomosis. The 3D reconstructed arterial segments are modeled as non-compliant 1.24 - 1.47 mm diameter ducts, with approximately 0.1 mm arterial thickness. The blood flow is considered laminar and the no-slip condition is imposed on the boundary wall, which is assumed to be rigid. In analyzing the results, the distribution of the wall shear stress (WSS) is presented in the region of interest, near the sutures. The results indicate that high values of WSS appear in the vicinity of sutures. Such regions may promote thrombus formation and subsequently anastomotic failure, therefore their meticulous study is of high importance.
{"title":"Modeling of blood flow through sutured micro-vascular anastomoses","authors":"G. Karanasiou, Dimitrios A. Gatsios, M. Lykissas, K. Stefanou, G. Rigas, I. Lagaris, Ioannis P. Kostas-Agnantis, I. Gkiatas, A. Beris, D. Fotiadis","doi":"10.1109/EMBC.2015.7318748","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7318748","url":null,"abstract":"Microanastomosis is a surgical procedure used to reconnect two blood vessels using sutures. The optimal microanastomosis may be predicted by assessing the factors that influence this invasive procedure. Blood flow and hemodynamics following microanastomosis are important factors for the successful longevity of this operation. How is the blood flow affected by the presence of sutures? Computational Fluid Dynamics (CFD) is a powerful tool that permits the estimation of specific quantities, such as fluid stresses, that are hardly measurable in vivo. In this study, we propose a methodology which evaluates the alterations in the hemodynamic status due to microanastomosis. A CFD model of a reconstructed artery has been developed, based on anatomical information provided by intravascular ultrasound and angiography, and was used to simulate blood flow after microanastomosis. The 3D reconstructed arterial segments are modeled as non-compliant 1.24 - 1.47 mm diameter ducts, with approximately 0.1 mm arterial thickness. The blood flow is considered laminar and the no-slip condition is imposed on the boundary wall, which is assumed to be rigid. In analyzing the results, the distribution of the wall shear stress (WSS) is presented in the region of interest, near the sutures. The results indicate that high values of WSS appear in the vicinity of sutures. Such regions may promote thrombus formation and subsequently anastomotic failure, therefore their meticulous study is of high importance.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"53 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123080872","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7318924
Ulises A. Aregueta-Robles, K. Lim, P. Martens, N. Lovell, L. Poole-Warren, R. Green
Hydrogels hold significant promise for supporting cell based therapies in the field of bioelectrodes. It has been proposed that tissue engineering principles can be used to improve the integration of neural interfacing electrodes. Degradable hydrogels based on poly (vinyl alcohol) functionalised with tyramine (PVA-Tyr) have been shown to support covalent incorporation of non-modified tyrosine rich proteins within synthetic hydrogels. PVA-Tyr crosslinked with such proteins, were explored as a scaffold for supporting development of neural tissue in a three dimensional (3D) environment. In this study a model neural cell line (PC12) and glial accessory cell line, Schwann cell (SC) were encapsulated in PVA-Tyr crosslinked with gelatin and sericin. Specifically, this study aimed to examine the growth and function of SC and PC12 co-cultures when translated from a two dimensional (2D) environment to a 3D environment. PC12 differentiation was successfully promoted in both 2D and 3D at 25 days post-culture. SC encapsulated as a single cell line and in co-culture were able to produce both laminin and collagen-IV which are required to support neuronal development. Neurite outgrowth in the 3D environment was confirmed by immunocytochemical staining. PVA-Tyr/sericin/gelatin hydrogel showed mechanical properties similar to nerve tissue elastic modulus. It is suggested that the mechanical properties of the PVA-Tyr hydrogels with native protein components are providing with a compliant substrate that can be used to support the survival and differentiation of neural networks.
{"title":"Producing 3D neuronal networks in hydrogels for living bionic device interfaces","authors":"Ulises A. Aregueta-Robles, K. Lim, P. Martens, N. Lovell, L. Poole-Warren, R. Green","doi":"10.1109/EMBC.2015.7318924","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7318924","url":null,"abstract":"Hydrogels hold significant promise for supporting cell based therapies in the field of bioelectrodes. It has been proposed that tissue engineering principles can be used to improve the integration of neural interfacing electrodes. Degradable hydrogels based on poly (vinyl alcohol) functionalised with tyramine (PVA-Tyr) have been shown to support covalent incorporation of non-modified tyrosine rich proteins within synthetic hydrogels. PVA-Tyr crosslinked with such proteins, were explored as a scaffold for supporting development of neural tissue in a three dimensional (3D) environment. In this study a model neural cell line (PC12) and glial accessory cell line, Schwann cell (SC) were encapsulated in PVA-Tyr crosslinked with gelatin and sericin. Specifically, this study aimed to examine the growth and function of SC and PC12 co-cultures when translated from a two dimensional (2D) environment to a 3D environment. PC12 differentiation was successfully promoted in both 2D and 3D at 25 days post-culture. SC encapsulated as a single cell line and in co-culture were able to produce both laminin and collagen-IV which are required to support neuronal development. Neurite outgrowth in the 3D environment was confirmed by immunocytochemical staining. PVA-Tyr/sericin/gelatin hydrogel showed mechanical properties similar to nerve tissue elastic modulus. It is suggested that the mechanical properties of the PVA-Tyr hydrogels with native protein components are providing with a compliant substrate that can be used to support the survival and differentiation of neural networks.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"62 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121832217","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7320019
D. Oloumi, P. Boulanger, A. Kordzadeh, K. Rambabu
This paper describes the possibility of detecting tumors in human breast using ultra-wideband (UWB) circular synthetic aperture radar (CSAR). CSAR is a subset of SAR which is a radar imaging technique using a circular data acquisition pattern. Tomographic image reconstruction is done using a time domain global back projection technique adapted to CSAR. Experiments are conducted on a breast phantoms made of pork fat emulating normal and cancerous conditions. Preliminary experimental results show that microwave imaging of a breast phantom using UWB-CSAR is a simple and low-cost method, efficiently capable of detecting the presence of tumors.
{"title":"Breast tumor detection using UWB circular-SAR tomographic microwave imaging","authors":"D. Oloumi, P. Boulanger, A. Kordzadeh, K. Rambabu","doi":"10.1109/EMBC.2015.7320019","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7320019","url":null,"abstract":"This paper describes the possibility of detecting tumors in human breast using ultra-wideband (UWB) circular synthetic aperture radar (CSAR). CSAR is a subset of SAR which is a radar imaging technique using a circular data acquisition pattern. Tomographic image reconstruction is done using a time domain global back projection technique adapted to CSAR. Experiments are conducted on a breast phantoms made of pork fat emulating normal and cancerous conditions. Preliminary experimental results show that microwave imaging of a breast phantom using UWB-CSAR is a simple and low-cost method, efficiently capable of detecting the presence of tumors.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115738251","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2015-11-05DOI: 10.1109/EMBC.2015.7319300
H. Almahasneh, N. Kamel, N. Walter, A. Malik
Using EEG signals, a novel technique for driver cognitive state assessment is presented, analyzed and experimentally verified. The proposed technique depends on the singular value decomposition (SVD) in finding the distributed energy of the EEG data matrix A in the direction of the r-principal subspace. This distribution is unique and sensitive to the changes in the cognitive state of the driver due to external stimuli, so it is used as a set of features for classification. The proposed technique is tested with 42 subjects using 128 EEG channels and the results show significant improvements in terms of accuracy, specificity, sensitivity, and false detection in comparison to other recently proposed techniques.
{"title":"r-principal subspace for driver cognitive state classification","authors":"H. Almahasneh, N. Kamel, N. Walter, A. Malik","doi":"10.1109/EMBC.2015.7319300","DOIUrl":"https://doi.org/10.1109/EMBC.2015.7319300","url":null,"abstract":"Using EEG signals, a novel technique for driver cognitive state assessment is presented, analyzed and experimentally verified. The proposed technique depends on the singular value decomposition (SVD) in finding the distributed energy of the EEG data matrix A in the direction of the r-principal subspace. This distribution is unique and sensitive to the changes in the cognitive state of the driver due to external stimuli, so it is used as a set of features for classification. The proposed technique is tested with 42 subjects using 128 EEG channels and the results show significant improvements in terms of accuracy, specificity, sensitivity, and false detection in comparison to other recently proposed techniques.","PeriodicalId":285228,"journal":{"name":"2015 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC)","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2015-11-05","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116989271","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}