Drought tolerance indices serve as valuable indicators for selecting cowpea genotypes with improved drought tolerance. However, there is a limited understanding of the variability and the impact of genotype (G) × environment (E) interaction (I) on these drought tolerance indices. Therefore, the objective of this study was to assess the extent of genetic variability and the influence of GEI on drought tolerance indices in cowpea. The experiment was conducted over two seasons under controlled conditions in a screen house. The results revealed that seed yield and all drought tolerance indices were significantly influenced by genotype, environment, and GEI. When the data from both years were combined, the yield under non-stress conditions ranged from 10.47 g in G2 to 17.27 g in G7, while under drought stress, it ranged from 2.19 g in G3 to 6.89 g in G1. Through mean rank analysis, principal component (PC) analysis, and clustering, highly tolerant accessions (G1 and G6) and highly susceptible ones (G2, G3, and G8) were identified. This study identified several indices, including geometric mean (GM), yield index (YI), mean productivity (MP), stress tolerance index (STI), modified stress tolerance index for non-stress (MST1), and stress (MST2), GMP, and HM, as effective in selecting high-yielding and drought-tolerant accessions under non-stress and drought conditions. Additionally, the drought resistance index (DRI) and yield stability index (YSI) were found to be reliable indicators under drought stress. Most of the indices exhibited moderate (≥ 30%) to high heritability (≥ 60%) and high genetic advance (≥ 20%), except for MST2, which had low heritability (12.73%).
{"title":"Genetic variation, genotype × environment interaction, and correlation among drought tolerance indices in cowpea","authors":"A. Ajayi","doi":"10.38058/ijsl.1319471","DOIUrl":"https://doi.org/10.38058/ijsl.1319471","url":null,"abstract":"Drought tolerance indices serve as valuable indicators for selecting cowpea genotypes with improved drought tolerance. However, there is a limited understanding of the variability and the impact of genotype (G) × environment (E) interaction (I) on these drought tolerance indices. Therefore, the objective of this study was to assess the extent of genetic variability and the influence of GEI on drought tolerance indices in cowpea. The experiment was conducted over two seasons under controlled conditions in a screen house. The results revealed that seed yield and all drought tolerance indices were significantly influenced by genotype, environment, and GEI. When the data from both years were combined, the yield under non-stress conditions ranged from 10.47 g in G2 to 17.27 g in G7, while under drought stress, it ranged from 2.19 g in G3 to 6.89 g in G1. Through mean rank analysis, principal component (PC) analysis, and clustering, highly tolerant accessions (G1 and G6) and highly susceptible ones (G2, G3, and G8) were identified. This study identified several indices, including geometric mean (GM), yield index (YI), mean productivity (MP), stress tolerance index (STI), modified stress tolerance index for non-stress (MST1), and stress (MST2), GMP, and HM, as effective in selecting high-yielding and drought-tolerant accessions under non-stress and drought conditions. Additionally, the drought resistance index (DRI) and yield stability index (YSI) were found to be reliable indicators under drought stress. Most of the indices exhibited moderate (≥ 30%) to high heritability (≥ 60%) and high genetic advance (≥ 20%), except for MST2, which had low heritability (12.73%).","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"110 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140453098","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Molecular arrangement and noncovalent interactions in organic materials greatly influence the charge mobility in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and organic field-effect transistors (OFETs). In the light of the this argument, we examined the electronic properties of the phenanthroline derivatives by considering the charge mobility with the combination of density functional theory and Marcus Charge Transfer Theory. The drift electron mobility of the molecule 1 and 2 were determined to 21.13 cm2 V-1 s-1 and 18.00 cm2 V-1 s-1, respectively through J type π⋯π stacking interactions created by small perpendicular distances between the adjacent rings. The effective charge pathways of the molecules were generated with strong π⋯π stacking interactions consolidated by noncovalent interactions in their solid phases. The electron reorganization energy for both molecules were determined smaller than that of holes which means they have n-type semiconductor properties. The charge transfer integrals were calculated with the optimization of molecules’ dimer configurations that the theoretical results demonstrate the charge transfer integral depends on the distance between the stacking rings. High charge transfer integral and small reorganization energy give the high charge mobility fort he semiconductor molecules. Beside the mobility, energy band gap, ionization potential, electron and hole injection barriers of the molecules were interpreted to further understand their electronic properties. Due to the small LUMO values which provide n-type molecule and small electron injection barrier. From the our work both molecules can be effective n type organic semiconductor devices with the high mobility and can be modified for more efficient charge transport in phenanthroline derivatives.
有机材料中的分子排列和非共价相互作用在很大程度上影响着有机发光二极管（OLED）、有机光伏（OPV）和有机场效应晶体管（OFET）中的电荷迁移率。有鉴于此，我们结合密度泛函理论和马库斯电荷转移理论，通过考虑电荷迁移率研究了菲罗啉衍生物的电子特性。通过相邻环之间较小的垂直距离产生的 J 型 π⋯π 堆积相互作用，确定了分子 1 和分子 2 的漂移电子迁移率分别为 21.13 cm2 V-1 s-1 和 18.00 cm2 V-1 s-1。分子的有效电荷通路是通过固相中的非共价相互作用巩固的强π⋯π堆积相互作用产生的。经测定，这两种分子的电子重组能均小于空穴，这意味着它们具有 n 型半导体特性。通过优化分子的二聚构型，计算了电荷转移积分，理论结果表明电荷转移积分取决于堆叠环之间的距离。高电荷转移积分和小重组能使半导体分子具有高电荷迁移率。除了迁移率之外，还对分子的能带间隙、电离电势、电子和空穴注入势垒进行了解释，以进一步了解它们的电子特性。由于 LUMO 值较小，这就提供了 n 型分子和较小的电子注入势垒。根据我们的研究成果，这两种分子都可以成为具有高迁移率的有效 n 型有机半导体器件，并且可以对菲罗啉衍生物进行改性，以提高电荷传输效率。
{"title":"Estimation of the Charge Mobility of Phenanthroline derivatives with the view of Density Functional Theory: Reorganization Energy and Charge Transfer Integral are in play","authors":"Zeynep TÜRKMEN BULCA, G. Yakalı","doi":"10.38058/ijsl.1300611","DOIUrl":"https://doi.org/10.38058/ijsl.1300611","url":null,"abstract":"Molecular arrangement and noncovalent interactions in organic materials greatly influence the charge mobility in organic light-emitting diodes (OLEDs), organic photovoltaics (OPVs), and organic field-effect transistors (OFETs). In the light of the this argument, we examined the electronic properties of the phenanthroline derivatives by considering the charge mobility with the combination of density functional theory and Marcus Charge Transfer Theory. The drift electron mobility of the molecule 1 and 2 were determined to 21.13 cm2 V-1 s-1 and 18.00 cm2 V-1 s-1, respectively through J type π⋯π stacking interactions created by small perpendicular distances between the adjacent rings. The effective charge pathways of the molecules were generated with strong π⋯π stacking interactions consolidated by noncovalent interactions in their solid phases. The electron reorganization energy for both molecules were determined smaller than that of holes which means they have n-type semiconductor properties. The charge transfer integrals were calculated with the optimization of molecules’ dimer configurations that the theoretical results demonstrate the charge transfer integral depends on the distance between the stacking rings. High charge transfer integral and small reorganization energy give the high charge mobility fort he semiconductor molecules. Beside the mobility, energy band gap, ionization potential, electron and hole injection barriers of the molecules were interpreted to further understand their electronic properties. Due to the small LUMO values which provide n-type molecule and small electron injection barrier. From the our work both molecules can be effective n type organic semiconductor devices with the high mobility and can be modified for more efficient charge transport in phenanthroline derivatives.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"58 22","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-02-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140453744","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The environmental factors are vital determinants for health and wellness of organisms. Because of the population increase, technological developments, more industrial activities and dense traffic, environmental pollution, and destruction became one of the major problems in the world. Various studies indicated that most of the diseases and health problems are closely related with negative environmental factors. Considering the roles and responsibilities of the nurses, increasing the knowledge and awareness of nursing students on environmental issues has vital importance in terms of protecting and improving health. This paper aimed to evaluate the studies on environmental attitudes, awareness, sensitivity, and literacy of nursing students in Turkey. This assessment is important to improve and upgrade these characteristics of nursing students and nurses. It also has an importance for public health. The results of the studies generally indicated that majority of the nursing students had moderate levels of environmental attitudes, awareness, sensitivity, and literacy. Most of the studies confirm that the levels of nursing students on these subjects closely related with components of nursing education and content and composition of subjects. the common result obtained from the studies is to increase the number of subjects and social activities on environmental issues in nursing education for higher environmental awareness, sensitivity, and literacy of nursing students, understanding, and eliminating the problems arising from environmental factors. Considering the roles and responsibilities of the nurses, increasing the knowledge and awareness of students on environmental issues has vital importance in terms of protecting and improving health.
{"title":"An overview of environmental attitudes, awareness, sensitivity, and literacy of nursing students in Turkey","authors":"N. Karavin, Gözde Yıldız Das Gecim, Aslı Memis","doi":"10.38058/ijsl.1256919","DOIUrl":"https://doi.org/10.38058/ijsl.1256919","url":null,"abstract":"The environmental factors are vital determinants for health and wellness of organisms. Because of the population increase, technological developments, more industrial activities and dense traffic, environmental pollution, and destruction became one of the major problems in the world. Various studies indicated that most of the diseases and health problems are closely related with negative environmental factors. Considering the roles and responsibilities of the nurses, increasing the knowledge and awareness of nursing students on environmental issues has vital importance in terms of protecting and improving health. This paper aimed to evaluate the studies on environmental attitudes, awareness, sensitivity, and literacy of nursing students in Turkey. This assessment is important to improve and upgrade these characteristics of nursing students and nurses. It also has an importance for public health. \u0000The results of the studies generally indicated that majority of the nursing students had moderate levels of environmental attitudes, awareness, sensitivity, and literacy. Most of the studies confirm that the levels of nursing students on these subjects closely related with components of nursing education and content and composition of subjects. the common result obtained from the studies is to increase the number of subjects and social activities on environmental issues in nursing education for higher environmental awareness, sensitivity, and literacy of nursing students, understanding, and eliminating the problems arising from environmental factors. Considering the roles and responsibilities of the nurses, increasing the knowledge and awareness of students on environmental issues has vital importance in terms of protecting and improving health.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131686716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The purpose of this study was to estimate the prevalence of tuberculosis among patients undergoing treatment at the ERCC medical centre in Alushi from January 2017 to July 2021. A total of 3029 TB presumptive patients were included in the current investigation. The overall TB prevalence was 43.57%. There were 993 (64.90%) males, 10.1% of whom were rifampicin resistant, and 537 (35.09%) females, 34.8% of whom were rifampicin resistant. The highest prevalence is recorded in all age groups, was seen in the age bracket 21-30 with a total of 350 (26.51%) and 327 (24.77%) in the age range 31-40. Findings revealed that having a history of TB medication and being female were both associated with the development of rifampicin-resistant Tuberculosis and patients aged 21 to 40 were more likely than others to be infected with tuberculosis and develop rifampicin-resistant tuberculosis. Because of the high prevalence, immediate action is essential to encourage early identification and the completion of DR-TB medication in order to prevent the disease from spreading in the community, as well as continuous community health education about tuberculosis and the risk of drug resistance
{"title":"PREVALENCE OF TUBERCULOSIS AND RIFAMPICIN RESISTANT Mycobacterium tuberculosis AMONG PATIENTS RECEIVING TREATMENT IN ERCC MEDICAL CENTER ALUSHI, NASARAWA STATE, NIGERIA.","authors":"Emmanuel Oboh","doi":"10.38058/ijsl.1233908","DOIUrl":"https://doi.org/10.38058/ijsl.1233908","url":null,"abstract":"The purpose of this study was to estimate the prevalence of tuberculosis among patients undergoing treatment at the ERCC medical centre in Alushi from January 2017 to July 2021. A total of 3029 TB presumptive patients were included in the current investigation. The overall TB prevalence was 43.57%. There were 993 (64.90%) males, 10.1% of whom were rifampicin resistant, and 537 (35.09%) females, 34.8% of whom were rifampicin resistant. The highest prevalence is recorded in all age groups, was seen in the age bracket 21-30 with a total of 350 (26.51%) and 327 (24.77%) in the age range 31-40. Findings revealed that having a history of TB medication and being female were both associated with the development of rifampicin-resistant Tuberculosis and patients aged 21 to 40 were more likely than others to be infected with tuberculosis and develop rifampicin-resistant tuberculosis. Because of the high prevalence, immediate action is essential to encourage early identification and the completion of DR-TB medication in order to prevent the disease from spreading in the community, as well as continuous community health education about tuberculosis and the risk of drug resistance","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-03-25","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121087529","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The objective of our study is to reveal the effects of paper cups sold under different brands on the aquatic test organisms, Daphnia magna and Artemia salina, which are frequently used in toxicity studies. To this end, survival rates of D. magna and A. salina individuals, which were kept alive after cooling in paper cups exposed to 20 °C and 80 °C, for 24, 48, 72, and 96 hours were determined. Upon examining the results, while no significant decrease was found in the survival rates of D. magna and A. salina individuals kept in glassware, a significant increase was identified in the mortality rates of individuals kept in paper glasses, especially at 72 and 96 hours. It was determined that whereas the mortality rates reached 40% in paper and plastic cups exposed to 20 °C water, the mortality rates reached 70% in paper cups exposed to 80 °C water. Moreover, regression was found in the developmental and reproductive characteristics of D. magna and A. salina individuals, which were kept in paper cups exposed to water at different temperatures, compared to the control group and individuals in glass cups. We think that this was caused by microplastics or some chemicals released into the water due to the deterioration of the film layer on the inner surface of the glass, especially due to the high temperature.
{"title":"A toxicity study on Daphnia magna and Artemia salina: Are paper cups safe?","authors":"M. Fidan, A. Ayar","doi":"10.38058/ijsl.1253973","DOIUrl":"https://doi.org/10.38058/ijsl.1253973","url":null,"abstract":"The objective of our study is to reveal the effects of paper cups sold under different brands on the aquatic test organisms, Daphnia magna and Artemia salina, which are frequently used in toxicity studies. To this end, survival rates of D. magna and A. salina individuals, which were kept alive after cooling in paper cups exposed to 20 °C and 80 °C, for 24, 48, 72, and 96 hours were determined. \u0000Upon examining the results, while no significant decrease was found in the survival rates of D. magna and A. salina individuals kept in glassware, a significant increase was identified in the mortality rates of individuals kept in paper glasses, especially at 72 and 96 hours. It was determined that whereas the mortality rates reached 40% in paper and plastic cups exposed to 20 °C water, the mortality rates reached 70% in paper cups exposed to 80 °C water. Moreover, regression was found in the developmental and reproductive characteristics of D. magna and A. salina individuals, which were kept in paper cups exposed to water at different temperatures, compared to the control group and individuals in glass cups. We think that this was caused by microplastics or some chemicals released into the water due to the deterioration of the film layer on the inner surface of the glass, especially due to the high temperature.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"19 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-02-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131762029","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
This study was carried out to determine the effects of different coating materials on weight loss (%) and sensory properties of daily (fresh) quail eggs. For this purpose, quail eggs were coated with molasses, molasses + agar, molasses + glycerine and whey and they were stored at room temperature. No coating material was used in the control group. It was determined that there was a very significant difference between the groups in terms of egg weight loss at all storage times (1st week, 2nd week, 3rd week, 4th week) (p
{"title":"Evaluation of weight loss and some sensory properties in quail eggs coated using different solutions (molasses, molasses + agar, molasses + glycerine, whey)","authors":"Fadime Seyrekoğlu, Gözde Kılınç","doi":"10.38058/ijsl.1153229","DOIUrl":"https://doi.org/10.38058/ijsl.1153229","url":null,"abstract":"This study was carried out to determine the effects of different coating materials on weight loss (%) and sensory properties of daily (fresh) quail eggs. For this purpose, quail eggs were coated with molasses, molasses + agar, molasses + glycerine and whey and they were stored at room temperature. No coating material was used in the control group. It was determined that there was a very significant difference between the groups in terms of egg weight loss at all storage times (1st week, 2nd week, 3rd week, 4th week) (p","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"80 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133154531","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The bacteriological profile of fresh spinach and cabbage sold in Lafia Modern Market were analyzed in the Microbiology laboratory of Nasarawa State Polytechnic, Lafia by homogenizing 1g of the sample in 10 ml of peptone water. An aliquot from a 10-fold serial dilution was inoculated using the pour plate method into the different bacteriological medium at 37oC for 24 hours. The total number of colonies was counted and identified using standard procedures. Results indicated that spinach had the highest average bacteria count of 1.4 x104CFU/g, 9.2x103CFU/g, and 6.1x103CFU/g Nutrient agar, MacConkey agar, and Salmonella-Shigella agar respectively, while cabbage had an average bacterial count of 1.0x104CFU/g, 6.0x103CFU/g and 4.1x103 CFU/g on Nutrient agar, MacConkey agar, and Salmonella-Shigella agar respectively. The genera of the bacteria isolates identified were Streptococcus spp (8%), Bacillus subtilis and Pseudomonas aeruginosa (15% each), Staphylococcus aureus (16%), Escherichia coli and Salmonella spp (23% each). These isolated bacteria are of public health importance due to their implication in food-borne illnesses. It is recommended that the hygiene level of the entire vegetable processing value chain should be improved in other to prevent or reduce bacterial contamination.
{"title":"BACTERIOLOGICAL-PROFILE OF SOME VEGETABLES SOLD IN LAFIA METROPOLIS, NASARAWA STATE, NIGERIA.","authors":"Emmanuel Oboh, P. Oleghe","doi":"10.38058/ijsl.1146634","DOIUrl":"https://doi.org/10.38058/ijsl.1146634","url":null,"abstract":"The bacteriological profile of fresh spinach and cabbage sold in Lafia Modern Market were analyzed in the Microbiology laboratory of Nasarawa State Polytechnic, Lafia by homogenizing 1g of the sample in 10 ml of peptone water. An aliquot from a 10-fold serial dilution was inoculated using the pour plate method into the different bacteriological medium at 37oC for 24 hours. The total number of colonies was counted and identified using standard procedures. Results indicated that spinach had the highest average bacteria count of 1.4 x104CFU/g, 9.2x103CFU/g, and 6.1x103CFU/g Nutrient agar, MacConkey agar, and Salmonella-Shigella agar respectively, while cabbage had an average bacterial count of 1.0x104CFU/g, 6.0x103CFU/g and 4.1x103 CFU/g on Nutrient agar, MacConkey agar, and Salmonella-Shigella agar respectively. The genera of the bacteria isolates identified were Streptococcus spp (8%), Bacillus subtilis and Pseudomonas aeruginosa (15% each), Staphylococcus aureus (16%), Escherichia coli and Salmonella spp (23% each). These isolated bacteria are of public health importance due to their implication in food-borne illnesses. It is recommended that the hygiene level of the entire vegetable processing value chain should be improved in other to prevent or reduce bacterial contamination.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"127 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"127420272","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
When canaries are sexually active, they mate during the breeding season. During this time, the female canary builds a nest. In the days following the completion of nest construction, they lay eggs and incubate. In artificial insemination, the skill of the practitioner and knowing the appropriate artificial insemination time increase the chance of success. In the study, 8 male and 8 female Gloster canaries were used. Artificial insemination practices arranged for each canary inseminated at different times were called groups. It was applied just before and after the nest construction of Group 1 was completed, Group 2 was applied when nest construction was started and the nest was completed, and Group 3 was applied when nesting material was given and the nest was completed. The female canaries were immediately inseminated by the cloacal method with semen taken from male breeders at different times of the nest building phase. Among group applications, it was observed that the 3rd group application was significantly successful when compared to the others. This study aims to determine the effects of artificial insemination applied at different times of the nest-building process on the fertilization of urea in canaries.
{"title":"The Effect of Artificial Insemination on Egg Fertilization at Different Times of Nest Construction in Gloster Canaries","authors":"A. Özkök","doi":"10.38058/ijsl.1152442","DOIUrl":"https://doi.org/10.38058/ijsl.1152442","url":null,"abstract":"When canaries are sexually active, they mate during the breeding season. During this time, the female canary builds a nest. In the days following the completion of nest construction, they lay eggs and incubate. In artificial insemination, the skill of the practitioner and knowing the appropriate artificial insemination time increase the chance of success. In the study, 8 male and 8 female Gloster canaries were used. Artificial insemination practices arranged for each canary inseminated at different times were called groups. It was applied just before and after the nest construction of Group 1 was completed, Group 2 was applied when nest construction was started and the nest was completed, and Group 3 was applied when nesting material was given and the nest was completed. The female canaries were immediately inseminated by the cloacal method with semen taken from male breeders at different times of the nest building phase. Among group applications, it was observed that the 3rd group application was significantly successful when compared to the others. This study aims to determine the effects of artificial insemination applied at different times of the nest-building process on the fertilization of urea in canaries.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"38 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-08-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"123810487","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Rabia Yaren Akkuş, Baris Bitmez, Seda Kuşoğlu Gültekin, Irem Albayrak, Fatih Özen, Yiğit Deveci, Y. Sıcak, E. Akalın, Ademi Fahri Pi̇rhan, Belkis Atasever Arslan
Alzheimer's disease is multi-component neurodegenerative disorder. Oxidative stress disrupts regular functioning of metabolism in early-onset Alzheimer's disease. It causes Tau phosphorylation, formation of neurofibrillary tangle and neuron reduction. Due to intense binding of phosphorylated amino acids to aluminum, it induces self-assembly and deposition of high degree of phosphorylated cytoskeletal proteins, such as microtubule and neurofilament-associated proteins. In this study, it is aimed to consider the antioxidant potential of Hypericum perforatum extract against neurotoxicity caused by Aluminum-maltolate (Al(mal)3) and its effects on APP gene expression. Four different groups were determined to observe the impact of H. perforatum extract. After the incubation of the cells for 24 hours, only the medium was placed in the first group as control. 500 μM Al(mal)3 was added to the second group of cells. 20 μg mL-1 Hypericum perforatum extract was added to the third group. For the fourth group, 20 μg mL-1 Hypericum perforatum extract and 500 μM Al(mal)3 were added. While Al(mal)3 increased total antioxidant status levels in SH-SY5Y human neuroblastoma cells, H. perforatum extract significantly inhibited Al(mal)3 induced oxidative stress. On the other hand, H. perforatum extract significantly decreased APP gene expression levels depending on Al(mal)3 toxicity in SH-SY5Y cells. According to these results, H. perforatum extract significantly inhibited Al(mal)3 neurotoxicity against SH-SY5Y cells. To determine synergistic and antagonistic effects of H. perforatum extract content is important to examine their specific effects of together with hyperforin, which is a phytochemical produced by some of the members of the plant genus Hypericum, to discover new therapeutic agents against neurodegeneration.
{"title":"Neuroprotective effect of Hypericum perforatum extract against Aluminum-maltolate induced toxicity in SH-SY5Y cells","authors":"Rabia Yaren Akkuş, Baris Bitmez, Seda Kuşoğlu Gültekin, Irem Albayrak, Fatih Özen, Yiğit Deveci, Y. Sıcak, E. Akalın, Ademi Fahri Pi̇rhan, Belkis Atasever Arslan","doi":"10.38058/ijsl.1121636","DOIUrl":"https://doi.org/10.38058/ijsl.1121636","url":null,"abstract":"Alzheimer's disease is multi-component neurodegenerative disorder. Oxidative stress disrupts regular functioning of metabolism in early-onset Alzheimer's disease. It causes Tau phosphorylation, formation of neurofibrillary tangle and neuron reduction. Due to intense binding of phosphorylated amino acids to aluminum, it induces self-assembly and deposition of high degree of phosphorylated cytoskeletal proteins, such as microtubule and neurofilament-associated proteins. In this study, it is aimed to consider the antioxidant potential of Hypericum perforatum extract against neurotoxicity caused by Aluminum-maltolate (Al(mal)3) and its effects on APP gene expression. Four different groups were determined to observe the impact of H. perforatum extract. After the incubation of the cells for 24 hours, only the medium was placed in the first group as control. 500 μM Al(mal)3 was added to the second group of cells. 20 μg mL-1 Hypericum perforatum extract was added to the third group. For the fourth group, 20 μg mL-1 Hypericum perforatum extract and 500 μM Al(mal)3 were added. While Al(mal)3 increased total antioxidant status levels in SH-SY5Y human neuroblastoma cells, H. perforatum extract significantly inhibited Al(mal)3 induced oxidative stress. On the other hand, H. perforatum extract significantly decreased APP gene expression levels depending on Al(mal)3 toxicity in SH-SY5Y cells. According to these results, H. perforatum extract significantly inhibited Al(mal)3 neurotoxicity against SH-SY5Y cells. To determine synergistic and antagonistic effects of H. perforatum extract content is important to examine their specific effects of together with hyperforin, which is a phytochemical produced by some of the members of the plant genus Hypericum, to discover new therapeutic agents against neurodegeneration.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"29 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-28","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131495075","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The most prominent feature of malnutrition that increases colon cancer is the use of laxatives. Most community-dwelling individuals self-manage the condition in bowel-related diseases and do not seek medical advice. Self-management often involves the use of laxative products that can be purchased over the counter from pharmacies and elsewhere. According to the researches, most of those who use herbal products do not get enough information about the products they use, and the most important problem is that they do not inform their health consultants (doctor, pharmacist, dietitian, nurse, etc.) about the product they use. Individuals get information about the product they use from transfers, uncontrolled media channels and the internet, and they reach the product easily. Long-term use of laxatives is predicted to impair healthy colonic function, produce laxative dependence, and damage the enteric nervous system and/or intestinal smooth muscle. It manages colon motility and may increase the risk of other types of cancer, especially colon cancer. In our study, the antiproliferative effect of Folliculj sennae plant, which is commonly used as a laxative, known as fasting herb, horseradish herb and camel eye herb and contains anthranoid laxative, on CCD-18Co (healthy colon epithelium) cell line and DLD-1 (colon cancer) and HT- 29 (colorectal cancer) cancer cell lines, on the other hand, aimed to determine its proliferative effect by MTT analysis.
{"title":"DETERMINATION OF THE ANTIPROLIFERATIVE EFFECT OF Folliculj Sennea USED AS A LAXATIVE ON CCD-18Co CELL LINE AND PROLIFERATIVE EFFECT ON DLD-1 AND HT-29 CANCER CELL LINES","authors":"Aybüke Afra Keski̇ner, Berna Kocaman","doi":"10.38058/ijsl.1140643","DOIUrl":"https://doi.org/10.38058/ijsl.1140643","url":null,"abstract":"The most prominent feature of malnutrition that increases colon cancer is the use of laxatives. Most community-dwelling individuals self-manage the condition in bowel-related diseases and do not seek medical advice. Self-management often involves the use of laxative products that can be purchased over the counter from pharmacies and elsewhere. According to the researches, most of those who use herbal products do not get enough information about the products they use, and the most important problem is that they do not inform their health consultants (doctor, pharmacist, dietitian, nurse, etc.) about the product they use. Individuals get information about the product they use from transfers, uncontrolled media channels and the internet, and they reach the product easily. Long-term use of laxatives is predicted to impair healthy colonic function, produce laxative dependence, and damage the enteric nervous system and/or intestinal smooth muscle. It manages colon motility and may increase the risk of other types of cancer, especially colon cancer. In our study, the antiproliferative effect of Folliculj sennae plant, which is commonly used as a laxative, known as fasting herb, horseradish herb and camel eye herb and contains anthranoid laxative, on CCD-18Co (healthy colon epithelium) cell line and DLD-1 (colon cancer) and HT- 29 (colorectal cancer) cancer cell lines, on the other hand, aimed to determine its proliferative effect by MTT analysis.","PeriodicalId":287513,"journal":{"name":"International Journal of Science Letters","volume":"34 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-07-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133721112","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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