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Introduction to the GRADE Approach for Evidence-Based Clinical Practice Guideline Development 基于证据的临床实践指南制定的GRADE方法简介
Pub Date : 2019-04-30 DOI: 10.14777/UTI.2019.14.1.26
E. Hwang, J. Jung
Copyright 2019, Korean Association of Urogenital Tract Infection and Inflammation. All rights reserved. This is an open access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. Editorial
韩国泌尿生殖道感染与炎症协会版权所有。版权所有。这是一篇在知识共享署名非商业许可(http://creativecommons.org/licenses/by-nc/4.0)条款下发布的开放获取文章,该许可允许在任何媒体上不受限制的非商业使用、分发和复制,前提是正确引用原创作品。编辑
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引用次数: 0
Changes in Antibiotic Resistance of Acute Bacterial Prostatitis in a Korean Single Center 韩国单一中心急性细菌性前列腺炎的抗生素耐药性变化
Pub Date : 2019-04-30 DOI: 10.14777/UTI.2019.14.1.14
Byounghoon Kim, Kwibok Choi, I. Cho, S. Min
Purpose: Acute bacterial prostatitis (ABP) is one of main infective disease in urology with various symptoms. Occurrence of complications can be minimized by appropriate treatment. We studied whether any changes in antimicrobial resistance of hospitalized ABP patients as time passed. Materials and Methods: The study was based on retrospective study. From 2004 to 2007 as past period and 2014 to 2017 as recent period defined. Patient’s ages, length of admission days, intensive care, urinalysis, strains, and resistance to antibiotics were investigated in hospitalized patients with ABP and compared between the two periods. Results: Fifty patients of past period and 72 patients of recent period with ABP were admitted. The mean age was increased 55.5±13.2 years to 62.0±15.3 years. The infection route was mostly community-acquired. Prostate biopsy-related was decreased 7 to 1. The mean of hospital days were 7.9±4.2 days to 6.9±3.4 days. Intensive care were 5 to 7. Average length of stay intensive care was 4.2±1.3 days to 4.1±1.4 days. Urine cultures showed no significant difference from the previous studies in strains. Extended spectrum beta-lactamases producing bacteria increased 4.3% to 25.0%, and third generation cephalosporin resistance was increased 13.0% to 40.9%. Fluoroquinolone was no significant change 26.1% to 27.3%. Aminoglycosides were identified in 4.3% to 6.8% and carbapenem in 4.3% to 2.3%. Conclusions: The mean age of hospitalized patients with ABP increased. Antimicrobial resistance did not change to fluoroquinolone, but extended spectrum beta-lactamases producing bacteria showed increased resistance to third-generation cephalosporin. Therefore, attention should be paid to the use of empirical antibiotics.
目的:急性细菌性前列腺炎(Acute bacterial prostatitis, ABP)是泌尿外科的主要感染性疾病之一,症状多样。适当的治疗可以减少并发症的发生。我们研究住院ABP患者的抗菌素耐药性是否随着时间的推移而发生变化。材料与方法:采用回顾性研究方法。2004年至2007年为过去期,2014年至2017年为最近期。对住院ABP患者的年龄、住院天数、重症监护情况、尿液分析、菌株及抗生素耐药性进行调查,并比较两期患者的差异。结果:既往ABP患者50例,近期ABP患者72例。平均年龄增加55.5±13.2岁至62.0±15.3岁。感染途径以社区获得性为主。前列腺活检相关性降低7比1。平均住院天数为7.9±4.2 ~ 6.9±3.4 d。重症监护5 - 7岁。重症监护平均住院时间为4.2±1.3 ~ 4.1±1.4天。尿培养显示与以往菌株的研究没有显著差异。产广谱β -内酰胺酶细菌增加4.3% ~ 25.0%,第三代头孢菌素耐药性增加13.0% ~ 40.9%。氟喹诺酮类药物无明显变化(26.1% ~ 27.3%)。氨基糖苷类占4.3% ~ 6.8%,碳青霉烯类占4.3% ~ 2.3%。结论:ABP住院患者平均年龄增加。对氟喹诺酮类药物的耐药性没有变化,但产生广谱β -内酰胺酶的细菌对第三代头孢菌素的耐药性增加。因此,应注意使用经验性抗生素。
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引用次数: 0
Comparison of Monomicrobial versus Polymicrobial Candiduria: Time to Awareness of Candiduria 单菌念珠菌与多菌念珠菌的比较:认识念珠菌的时间
Pub Date : 2019-04-30 DOI: 10.14777/UTI.2019.14.1.20
Hyunji Kim, Mi-Kyung Lee, Tae-Hyoung Kim
Purpose: Candiduria, which is the presence of Candida species in urine, is becoming increasingly common in hospital settings. These normal commensals in humans are often associated with the presence of other microorganisms. In this study, patients presenting with monomicrobial and polymicrobial candiduria were compared. Materials and Methods: A retrospective study was performed on the demographic, clinical, and laboratory data of 185 patients presenting with candiduria between July 2014 and June 2015 at Chung-Ang University Hospital. The threshold for a positive Candida species urine culture was set to 103 CFU/ml. Data on the following were evaluated: distribution of Candida species; patient age and sex; length of hospital stay; presence of diabetes mellitus (DM), chronic kidney disease (CKD), a urinary catheter, and fever; antibiotic administration; urinalysis; complete blood cells; and C-reactive protein. Results: Monomicrobial candiduria was more common (128/185, 69.2%) than polymicrobial candiduria (57/185, 30.8%). The most prevalent species was Candida albicans (monomicrobial vs. polymicrobial candiduria, 61.7% vs. 54.4%), followed in order by Candida tropicalis (18.8% vs. 24.6%), and Candida glabrata (14.8% vs. 12.3%), with no significant difference between the two groups. Significant differences in the length of stay, underlying DM or CKD, accompanying symptoms, and urine white blood cells (WBC) and bacterial counts were observed between the two groups (p<0.05). Conclusions: The length of stay, underlying DM or CKD, accompanying symptoms, and urine WBC and bacterial counts were more associated with polymicrobial candiduria. The early detection and treatment of candiduria will become increasingly important as the Korean population ages.
目的:念珠菌是尿液中念珠菌的存在,在医院环境中变得越来越普遍。人类的这些正常共生菌通常与其他微生物的存在有关。在这项研究中,比较了单微生物和多微生物念珠菌的患者。材料与方法:对2014年7月至2015年6月在中央大学医院就诊的185例念珠菌患者的人口学、临床和实验室资料进行回顾性研究。念珠菌尿培养阳性阈值设为103 CFU/ml。评估了以下数据:念珠菌种类的分布;患者年龄、性别;住院时间;存在糖尿病(DM)、慢性肾脏疾病(CKD)、导尿和发烧;抗生素管理;验尿;完整血细胞;和c反应蛋白。结果:单菌念珠菌(128/185,69.2%)多于多菌念珠菌(57/185,30.8%)。最常见的菌种为白色念珠菌(单菌念珠菌vs多菌念珠菌,61.7% vs 54.4%),其次为热带念珠菌(18.8% vs 24.6%)和光秃念珠菌(14.8% vs 12.3%),两组间差异无统计学意义。两组患者的住院时间、潜在的DM或CKD、伴随症状、尿白细胞(WBC)和细菌计数均有显著差异(p<0.05)。结论:住院时间、潜在的DM或CKD、伴随症状、尿白细胞和细菌计数与多微生物念珠菌病更相关。随着韩国人口的老龄化,念珠菌的早期发现和治疗将变得越来越重要。
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引用次数: 0
Perioperative Risk Factors Related to Systemic Inflammatory Response Syndrome after Percutaneous Nephrolithotomy 经皮肾镜取石术后全身炎症反应综合征的围手术期危险因素分析
Pub Date : 2019-04-30 DOI: 10.14777/UTI.2019.14.1.9
H. Chung, S. Jung
Percutaneous nephrolithotomy (PCNL) has become the standard treatment for large and complex kidney stones since its introduction in 1976. On the other hand, postoperative complications are not rare and can be quite significant. Of these complications, postoperative infectious complications, such as systemic inflammatory response syndrome (SIRS), remain a seminal event and a possible cause of perioperative mortality. Several recent studies have found a number of factors that increase the risk of SIRS after PCNL. These include preoperative factors (patient’s characteristics) and factors associated with the intraoperative and postoperative findings. The present study describes the perioperative risk factors of SIRS after PCNL. These findings can help decrease the incidence of infectious complications, including SIRS, in patients undergoing PCNL.
自1976年引入以来,经皮肾镜取石术(PCNL)已成为大型复杂肾结石的标准治疗方法。另一方面,术后并发症并不罕见,而且可能相当严重。在这些并发症中,术后感染性并发症,如全身炎症反应综合征(SIRS),仍然是一个重要事件,也是围手术期死亡的可能原因。最近的几项研究发现了一些增加PCNL后SIRS风险的因素。这些因素包括术前因素(患者的特征)以及与术中和术后发现相关的因素。本研究描述了PCNL术后SIRS的围手术期危险因素。这些发现有助于减少PCNL患者感染性并发症(包括SIRS)的发生率。
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引用次数: 1
Korean Translation of the GRADE Series Published in the BMJ, ‘GRADE: An Emerging Consensus on Rating Quality of Evidence and Strength of Recommendations’ (A Secondary Publication) 发表在BMJ的GRADE系列的韩文翻译,“GRADE:关于评价证据质量和建议强度的新共识”(二级出版物)
Pub Date : 2019-04-30 DOI: 10.14777/UTI.2019.14.1.28
Do Kyung Kim, E. Hwang, H. Kang, J. Ku, Hyun Jin Jung, H. Kim, J. Jung
Department of Urology, Soonchunhyang University Seoul Hospital, Soonchunhyang University College of Medicine, Seoul, 1 Department of Urology, Chonnam National University Medical School, Gwangju, 2 Department of Urology, Chungbuk National University College of Medicine, Cheongju, 3 Department of Urology, Pusan National University Hospital, Busan, 4 Department of Urology, Daegu Catholic University School of Medicine, Daegu, 5 Department of Urology, College of Medicine, Konyang University, Daejeon, 6 Department of Urology, 7 Institute of Evidence Based Medicine, Yonsei University Wonju College of Medicine, Wonju, Korea
泌尿外科学系Soonchunhyang首尔大学医院,Soonchunhyang大学医学院,首尔1泌尿外科学系Chonnam国立大学医学院,光州,2泌尿外科部门,来自韩国忠北国立大学医学院,所领导3泌尿外科学系,釜山国立大学医院,釜山4泌尿外科学系,大邱天主教大学医学院,大邱,5部泌尿外科,医学院Konyang大学大田,6泌尿外科,7循证医学研究所,延世大学原州医学院,韩国原州
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引用次数: 0
Recommendations for Antibacterial Prophylaxis in Endourological Procedures 泌尿道手术中抗菌预防的建议
Pub Date : 2019-04-01 DOI: 10.14777/UTI.2019.14.1.1
D. Y. Chung, J. Lee
This review discusses the evidence and newly identified findings of antibiotic prophylaxis in endourological procedures based on recently published studies. Endoscopic procedures and surgeries are performed widely to treat a variety of urologic diseases. The panel of European Association of Urology (EAU) guidelines on UTIs decided not to make recommendations for specific agents for particular procedures because there are considerable variations in Europe and worldwide regarding bacterial pathogens, their susceptibility, and the availability of antibiotic agents in 2018. In the EAU guidelines, antimicrobial prophylactic therapies cannot decrease the rate of symptomatic UTI in several procedures, including cystoscopy and extracorporeal shock wave lithotripsy. Perioperative antibiotic prophylaxis can be helpful in all patients undergoing endourological treatment, including ureteroscopic surgery and percutaneous nephrolithotomy. Because the urological practice is a part of the surgery, most urological treatment can be performed mainly by surgery. The prevention of surgical infections in each surgical field is a critical issue, but the evidence and number of guidelines are limited.
本综述根据最近发表的研究讨论了在泌尿道手术中抗生素预防的证据和新发现。内镜手术和手术被广泛用于治疗各种泌尿系统疾病。欧洲泌尿外科协会(EAU)尿路感染指南小组决定不对特定手术的特定药物提出建议,因为2018年欧洲和全球在细菌病原体、其易感性和抗生素药物的可用性方面存在相当大的差异。在EAU指南中,抗菌素预防性治疗不能降低包括膀胱镜检查和体外冲击波碎石术在内的几种手术中出现症状性尿路感染的发生率。围手术期抗生素预防对所有接受泌尿道内治疗的患者都有帮助,包括输尿管镜手术和经皮肾镜取石术。由于泌尿外科实践是外科的一部分,大多数泌尿外科治疗可以主要通过手术进行。预防手术感染是每个手术领域的关键问题,但证据和指南的数量有限。
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引用次数: 4
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Urogenital Tract Infection
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