Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794
S. Roberts, M. Richardson, T. Hinks, P. Howarth, P. Bradding, S. Wenzel, S. Siddiqui
{"title":"Development of an Epithelial-Derived Airflow Obstruction Gene Expression Signature Using Systems Approaches","authors":"S. Roberts, M. Richardson, T. Hinks, P. Howarth, P. Bradding, S. Wenzel, S. Siddiqui","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3794","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"24 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125161179","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829
D. Winnica, Sunita Sharma, L. Que, S. Ye, V. Smith, M. Cruse, N. Perez, F. Holguin
{"title":"Up-Regulation of Paraoxonase 2 in Human Bronchial Epithelial Cells","authors":"D. Winnica, Sunita Sharma, L. Que, S. Ye, V. Smith, M. Cruse, N. Perez, F. Holguin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3829","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"118 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116448354","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823
Denis Naumov, O. Kotova, D. Gassan, A. Prikhodko, V. Kolosov
{"title":"Sex-Dependent Effect of TRPM8 rs10166942 Polymorphism on Cold-Induced Airway Hyperresponsiveness in Asthma","authors":"Denis Naumov, O. Kotova, D. Gassan, A. Prikhodko, V. Kolosov","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3823","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129610691","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793
S. Liao, A. Linderholm, Megan Showalter, L. Franzi, O. Fiehn, A. Zeki, N. Kenyon
{"title":"Associations Between Arginine Metabolism Related Metabolites and Clinical Outcomes-A Longitudinal Metabolomic Study","authors":"S. Liao, A. Linderholm, Megan Showalter, L. Franzi, O. Fiehn, A. Zeki, N. Kenyon","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3793","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129251795","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803
T. Saito, T. Ichikawa, N. Fujino, T. Numakura, Y. Sasaki, K. Itakura, M. Yamada, H. Sugiura, M. Ichinose
{"title":"The Decrease of Mitochondrial Biogenesis Contributes Airway Epithelial Barrier Dysfunction in Asthma","authors":"T. Saito, T. Ichikawa, N. Fujino, T. Numakura, Y. Sasaki, K. Itakura, M. Yamada, H. Sugiura, M. Ichinose","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3803","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"17 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121596548","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807
Masato Watanabe, Mitsuru Sada, Keitaro Nakamoto, Toshiya Inui, Yukari Ogawa, Masaki Tamura, T. Yokoyama, K. Honda, T. Saraya, D. Kurai, H. Ishii, H. Takizawa
{"title":"sST2/IL-33 Balance Regulates Neutrophil-Related Cytokine Release in the Human Airways","authors":"Masato Watanabe, Mitsuru Sada, Keitaro Nakamoto, Toshiya Inui, Yukari Ogawa, Masaki Tamura, T. Yokoyama, K. Honda, T. Saraya, D. Kurai, H. Ishii, H. Takizawa","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3807","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"188 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115105111","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800
M. Ketelaar, M. Portelli, F. N. Dijk, A. Faiz, N. Shrine, J. Hankinson, S. Bhaker, A. Henry, C. Billington, D. Shaw, S. Johnson, A. Benest, Z. Pogson, A. Fogarty, T. McKeever, A. Singapuri, L. Heaney, A. Mansur, R. Gaudhuri, N. Thomson, J. Holloway, G. Lockett, P. Howarth, R. Niven, A. Simpson, M. Tobin, D. Postma, I. Hall, L. Wain, C. Brightling, M. Obeidat, D. Sin, M. Berge, G. Koppelman, I. Sayers, M. Nawijn
{"title":"Functional Translation of IL33 Locus Polymorphisms Into Altered Epithelial Cell Function Underlying Asthma","authors":"M. Ketelaar, M. Portelli, F. N. Dijk, A. Faiz, N. Shrine, J. Hankinson, S. Bhaker, A. Henry, C. Billington, D. Shaw, S. Johnson, A. Benest, Z. Pogson, A. Fogarty, T. McKeever, A. Singapuri, L. Heaney, A. Mansur, R. Gaudhuri, N. Thomson, J. Holloway, G. Lockett, P. Howarth, R. Niven, A. Simpson, M. Tobin, D. Postma, I. Hall, L. Wain, C. Brightling, M. Obeidat, D. Sin, M. Berge, G. Koppelman, I. Sayers, M. Nawijn","doi":"10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800","DOIUrl":"https://doi.org/10.1164/AJRCCM-CONFERENCE.2019.199.1_MEETINGABSTRACTS.A3800","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129932794","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830
H. Ueno, T. Koya, K. Tsukioka, H. Takeuchi, Masahito Hayashi, T. Hasegawa, E. Suzuki, T. Kikuchi
{"title":"Analysis of the Mechanism of Exercise Induced Bronchoconstriction in Murine Model","authors":"H. Ueno, T. Koya, K. Tsukioka, H. Takeuchi, Masahito Hayashi, T. Hasegawa, E. Suzuki, T. Kikuchi","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3830","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"129207099","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804
J. Jude, S. Xu, A. Schwab, N. Karmacharya, G. Cao, W. Jester, R. Panettieri
{"title":"Free Fatty Acid Receptor 1 (FFAR1) Agonist GW9508 Attenuates Excitation-Contraction Coupling in Human Airway Smooth Muscle (HASM) Cells","authors":"J. Jude, S. Xu, A. Schwab, N. Karmacharya, G. Cao, W. Jester, R. Panettieri","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3804","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"38 10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130086653","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2019-05-01DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799
M. Morr, K. Salka, Geovanny F. Perez, C. Rodríguez‐Martínez, J. A. Castro-Rodriguez, G. Nino
{"title":"Identification of Sub-Sets of Viral Bronchiolitis Based on Clinical Phenotyping, Quantitative Lung Imaging, Respiratory Outcomes and Airway Immune Responses","authors":"M. Morr, K. Salka, Geovanny F. Perez, C. Rodríguez‐Martínez, J. A. Castro-Rodriguez, G. Nino","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a3799","url":null,"abstract":"","PeriodicalId":287855,"journal":{"name":"B62. ASTHMA MECHANISMS","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122271993","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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