首页 > 最新文献

Fertility/Pregnancy最新文献

英文 中文
2022-RA-595-ESGO Ovarian stem cells from cryopreserved ovarian cortex: a potential for neo-oogenesis in women with cancer-treatment related infertility 来自冷冻卵巢皮质的卵巢干细胞:癌症治疗相关不孕症女性新卵发生的潜力
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.368
E. Silvestris, C. Minoia, A. Cazzolla, A. Kardhashi, G. De Palma, F. Arezzo, V. Loizzi, Raffaella de Palo, M. Dellino, G. Cormio
{"title":"2022-RA-595-ESGO Ovarian stem cells from cryopreserved ovarian cortex: a potential for neo-oogenesis in women with cancer-treatment related infertility","authors":"E. Silvestris, C. Minoia, A. Cazzolla, A. Kardhashi, G. De Palma, F. Arezzo, V. Loizzi, Raffaella de Palo, M. Dellino, G. Cormio","doi":"10.1136/ijgc-2022-esgo.368","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.368","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"81 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114254735","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-1182-ESGO Successful term pregnancy following radical trachelectomy in a patient with early-stage invasive cervical carcinoma: the first case reported from Vietnam 一例早期浸润性宫颈癌根治性气管切除术后足月妊娠成功:越南首例报道
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.381
N. T. Doan, T. Van Nguyen, L. Ta
{"title":"2022-RA-1182-ESGO Successful term pregnancy following radical trachelectomy in a patient with early-stage invasive cervical carcinoma: the first case reported from Vietnam","authors":"N. T. Doan, T. Van Nguyen, L. Ta","doi":"10.1136/ijgc-2022-esgo.381","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.381","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"39 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125482449","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-848-ESGO Obstetric and neonatal outcomes after breast cancer: a population-based study 乳腺癌后的产科和新生儿结局:一项基于人群的研究
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.376
Kirsten A Jorgensen, R. Nitecki, H. Nichols, Shuangshuang Fu, Chi-Fang Wu, A. Melamed, P. Brady, M. Gregor, M. Clapp, S. Giordano, J. Rauh-Hain
cancer
癌症
{"title":"2022-RA-848-ESGO Obstetric and neonatal outcomes after breast cancer: a population-based study","authors":"Kirsten A Jorgensen, R. Nitecki, H. Nichols, Shuangshuang Fu, Chi-Fang Wu, A. Melamed, P. Brady, M. Gregor, M. Clapp, S. Giordano, J. Rauh-Hain","doi":"10.1136/ijgc-2022-esgo.376","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.376","url":null,"abstract":"cancer","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"22 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132733818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-1545-ESGO Uterine transposition: is it an option for fertility sparing in locally advanced cervical cancer 子宫转位:是局部晚期宫颈癌保留生育能力的一种选择吗
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.390
Maria Ercilia Ibarra, Sebastián Altuna, Martín Mariano Ballarin, M. Betti, C. Maya, Tomás Demarco, J. Balparda
factors for recurrence. 35 patients were treated with a recurrence of a BOT. FSS was repeated in 11 (36.7%) patients. After FSS, the recurrence rate was 1/11 (9%). After complete surgical staging,
复发的因素。35例患者接受了BOT复发治疗。11例(36.7%)患者重复FSS。FSS术后复发率为1/11(9%)。完成手术分期后,
{"title":"2022-RA-1545-ESGO Uterine transposition: is it an option for fertility sparing in locally advanced cervical cancer","authors":"Maria Ercilia Ibarra, Sebastián Altuna, Martín Mariano Ballarin, M. Betti, C. Maya, Tomás Demarco, J. Balparda","doi":"10.1136/ijgc-2022-esgo.390","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.390","url":null,"abstract":"factors for recurrence. 35 patients were treated with a recurrence of a BOT. FSS was repeated in 11 (36.7%) patients. After FSS, the recurrence rate was 1/11 (9%). After complete surgical staging,","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"47 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116540818","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-185-ESGO Results after conservative surgery of stage II/III serous borderline ovarian tumors II/III期浆液性交界性卵巢肿瘤保守手术后的结果
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.364
S. Gouy, S. Maria, A. Maulard, S. Schérier, F. Zaccarini, P. Pautier, A. Leary, C. Genestie, C. Chargari, P. Morice
{"title":"2022-RA-185-ESGO Results after conservative surgery of stage II/III serous borderline ovarian tumors","authors":"S. Gouy, S. Maria, A. Maulard, S. Schérier, F. Zaccarini, P. Pautier, A. Leary, C. Genestie, C. Chargari, P. Morice","doi":"10.1136/ijgc-2022-esgo.364","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.364","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"128071936","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-1533-ESGO Role of fertility sparing surgery in patients with borderline ovarian tumors 保留生育能力手术在交界性卵巢肿瘤患者中的作用
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.389
T. Westermann, F. Heitz, B. Ataseven, N. Pauly, M. Moubarak, A. Strojna, S. Kaiser, Concin Nicole, J. Welz, V. Vrentas, T. Dagres, M. Imterat, H. Plett, A. Traut, A. Bois, P. Harter
{"title":"2022-RA-1533-ESGO Role of fertility sparing surgery in patients with borderline ovarian tumors","authors":"T. Westermann, F. Heitz, B. Ataseven, N. Pauly, M. Moubarak, A. Strojna, S. Kaiser, Concin Nicole, J. Welz, V. Vrentas, T. Dagres, M. Imterat, H. Plett, A. Traut, A. Bois, P. Harter","doi":"10.1136/ijgc-2022-esgo.389","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.389","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"23 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115424116","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-689-ESGO Fertility-sparing treatment in patients with IB1 cervical cancer – results of the international multicentre retrospective FERTISS study (ENGOT Cx14; CEEGOG Cx-03) IB1型宫颈癌患者保留生育能力的治疗——国际多中心回顾性FERTISS研究结果(ENGOT Cx14;CEEGOG Cx-03)
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.372
J. Sláma, I. Runnebaum, G. Scambia, M. Ángeles, K. Bahrehmand, S. Kommoss, A. Fagotti, F. Narducci, O. Matylevich, J. Holly, F. Martinelli, M. Koual, V. Kopetskyi, A. El-Balat, G. Corrado, M. Căpîlna, W. Schroder, Z. Novak, A. Shushkevich, L. Fricová, D. Cibula
{"title":"2022-RA-689-ESGO Fertility-sparing treatment in patients with IB1 cervical cancer – results of the international multicentre retrospective FERTISS study (ENGOT Cx14; CEEGOG Cx-03)","authors":"J. Sláma, I. Runnebaum, G. Scambia, M. Ángeles, K. Bahrehmand, S. Kommoss, A. Fagotti, F. Narducci, O. Matylevich, J. Holly, F. Martinelli, M. Koual, V. Kopetskyi, A. El-Balat, G. Corrado, M. Căpîlna, W. Schroder, Z. Novak, A. Shushkevich, L. Fricová, D. Cibula","doi":"10.1136/ijgc-2022-esgo.372","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.372","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"36 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121130881","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
2022-RA-1232-ESGO Key aspects of fertility preservation in cancer patients 癌症患者生育能力保存的关键方面
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.382
O. Lavrinovich, M. Yakovleva, O. Smirnova, A. Urmancheeva, I. Berlev
{"title":"2022-RA-1232-ESGO Key aspects of fertility preservation in cancer patients","authors":"O. Lavrinovich, M. Yakovleva, O. Smirnova, A. Urmancheeva, I. Berlev","doi":"10.1136/ijgc-2022-esgo.382","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.382","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125733584","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-756-ESGO High grade squamous intraepithelial lesions in pregnancy: case series of 35 patients 妊娠期高级别鳞状上皮内病变:35例病例
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.373
O. P. Matylevich, Ilya A Tarasau, Tatsiana U Vertsikhouskaya, Sviatlana Shelkovich
{"title":"2022-RA-756-ESGO High grade squamous intraepithelial lesions in pregnancy: case series of 35 patients","authors":"O. P. Matylevich, Ilya A Tarasau, Tatsiana U Vertsikhouskaya, Sviatlana Shelkovich","doi":"10.1136/ijgc-2022-esgo.373","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.373","url":null,"abstract":"","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"13 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"114994399","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
2022-RA-160-ESGO Fertility preservation in patients with early cervical cancer after organ-sparing surgery: retrospective monocentric study 保留器官手术后早期宫颈癌患者生育能力的保存:回顾性单中心研究
Pub Date : 2022-10-01 DOI: 10.1136/ijgc-2022-esgo.363
O. P. Matylevich, Ilya A Tarasau, I. Bakinouskaya, Sviatlana Shelkovich
2022-RA-154-ESGO Figure 1 Histopathologic findings in ovaries of pregnant mice exposed to chemotherapy. (A) Short exposure experiment (sacrifice at GD 15.5). (B) Long exposure experiment (sacrifice at GD 18.5). (C) Overview of normal ovary containing preantral (p: primary, s: secondary), antral (an: antal, an*: antral preovulatory), and atretic (ar) follicles, and corpora lutea (c). (D) Normal preantral follicle. (E) Apoptosis in preantral follicles, arrows indicate apoptotic cells. (F) IHC of Caspase-3 in preantral follicle, arrows indicate positively stained granulosa cells. (G)Necrosis of granulosa cells of the follicle, star indicates area of necrotic cells. Scale bars: C=100 mm, D-F=10 mm, G=20 mm Abstract 2022-RA-154-ESGO Figure 2 Phospho-H2AX Immunohistochemistry of primordial follicles in pregnant mice of short exposure experiment. (A)) Expression versus non-expression of phospho-H2AX in primordial follicles per treatment modality (n = 6 mice in control group and n = 3 mice per chemotherapeutic agent). Examples of staining of primordial follicles in (B) control group (non-expression), (C) carboplatin group (expression), and (D) cyclophosphamide high dose group (expression). Arrows indicate primordial follicles. Scale bar: B-D = 10 mm2022-RA-154-ESGO Figure 2 Phospho-H2AX Immunohistochemistry of primordial follicles in pregnant mice of short exposure experiment. (A)) Expression versus non-expression of phospho-H2AX in primordial follicles per treatment modality (n = 6 mice in control group and n = 3 mice per chemotherapeutic agent). Examples of staining of primordial follicles in (B) control group (non-expression), (C) carboplatin group (expression), and (D) cyclophosphamide high dose group (expression). Arrows indicate primordial follicles. Scale bar: B-D = 10 mm Conclusion Despite physiological ovarian function suppression during gestation, chemotherapy-induced damage of the ovaries occurs in pregnant mouse models, potentially affecting future fertility. 2022-RA-160-ESGO FERTILITY PRESERVATION IN PATIENTS WITH EARLY CERVICAL CANCER AFTER ORGAN-SPARING SURGERY: RETROSPECTIVE MONOCENTRIC STUDY Olga P Matylevich, Ilya A Tarasau, Iryna Y Bakinouskaya, Sviatlana Y Shelkovich. NN Alexandrov National Cancer Centre of Belarus, Minsk, Belarus; Belarusian Medical Academy of Postgraduate Education, Minsk, Belarus 10.1136/ijgc-2022-ESGO.363 Introduction/Background To assess the desire for motherhood, reproductive and obstetric outcomes in young patients with early cervical cancer treated with fertility-sparing surgery (FSS). Methodology All women £ 45 years who underwent FSS for early cervical cancer (stages IA1-IB1) at NN Alexandrov National Cancer Centre of Belarus between January 2010 and December 2020 were retrospectively identified. Fertility-sparing options included cold knife conization (CKC) in 46 patients, CKC and pelvic lymph node dissection (PLND) – in 12, abdominal radical trachelectomy (ART) – in 46, and laparoscopic radical trachelecto
图1化疗后妊娠小鼠卵巢组织病理学变化。(A)短暴露实验(GD 15.5牺牲)。(B)长时间暴露实验(GD 18.5牺牲)。(C)正常卵巢概述,包括前腔(p:原发性,s:继发性),前腔(an:前腔,an:前腔),闭锁(ar)卵泡和黄体(C)。(D)正常的前腔卵泡。(E)窦前卵泡凋亡,箭头表示凋亡细胞。(F)腔前卵泡Caspase-3免疫组化,箭头表示颗粒细胞染色阳性。(G)卵泡颗粒细胞坏死,星形表示坏死细胞区域。图2短暴露实验妊娠小鼠原始卵泡磷酸化- h2ax免疫组织化学。(A)不同治疗方式的原始卵泡中phospho-H2AX的表达与不表达(对照组n = 6,每种化疗药物n = 3)。(B)对照组(未表达)、(C)卡铂组(表达)、(D)环磷酰胺高剂量组(表达)原始卵泡染色例。箭头表示原始卵泡。图2短暴露实验妊娠小鼠原始卵泡磷酸化- h2ax免疫组织化学。(A)不同治疗方式的原始卵泡中phospho-H2AX的表达与不表达(对照组n = 6,每种化疗药物n = 3)。(B)对照组(未表达)、(C)卡铂组(表达)、(D)环磷酰胺高剂量组(表达)原始卵泡染色例。箭头表示原始卵泡。结论尽管妊娠期卵巢生理性功能受到抑制,但妊娠小鼠模型仍存在化疗引起的卵巢损伤,可能影响未来的生育能力。保留器官手术后早期宫颈癌患者的生育能力保存:回顾性单中心研究白俄罗斯亚历山德罗夫国家癌症中心,白俄罗斯明斯克;白俄罗斯研究生教育医学院,白俄罗斯,明斯克10.1136/ijgc-2022-ESGO.363前言/背景:评估接受保留生育手术(FSS)治疗的早期宫颈癌年轻患者的母性愿望、生殖和产科结局。方法回顾性分析2010年1月至2020年12月在白俄罗斯亚历山德罗夫国家癌症中心接受FSS治疗早期宫颈癌(IA1-IB1期)的所有45岁女性。保留生育能力的选择包括46例患者的冷刀锥切术(CKC), 12例患者的CKC和盆腔淋巴结清扫术(PLND), 46例患者的腹部根治性气管切除术(ART)和12例患者的腹腔镜根治性气管切除术(LRT)。从医疗记录和调查问卷中审查了有关生育意愿和生育结果的数据。结果共分析116例患者。6例CKC后患者缺乏产科结局数据,3例抗逆转录病毒治疗后出现闭经。研究了107例患者的生殖结局。随访时间中位数为50.8个月(范围16.4-92.7)。在随访期间,107例患者中有46例(43.0%)试图怀孕。11例患者14例妊娠均自然发生,临床妊娠率为23.9%(11/46)。有2例妊娠早期自然流产,2例妊娠早期因流产而终止,1例输卵管异位妊娠终止,2例妊娠仍在继续。14例妊娠中有7例(50.0%)足月活产。所有CKC或CKC合并PLND患者的分娩(7)都被记录下来。结论FSS后,不到一半(43.0%)的患者保持生育意愿。所有受孕都是自发的,占23.9%,这反映了在这类患者中需要广泛使用辅助生殖技术。在生殖结果方面,与ART和LRT相比,CKC具有明显的微创手术优势。2022-RA-185-ESGO II/III期浆液性交界性卵巢肿瘤保守手术后结果Sebastien Gouy, Sophie Maria, Amandine Maulard, Stephanie Scherier, Francois Zaccarini, Patricia Pautier, Alexandra Leary, Catherine Genestie, Cyrus Chargari, Philippe Morice。Gustave Roussy, Villejuif,法国10.1136/ijgc-2022-ESGO.364本研究的目的是通过长期随访评估大量II期或III期卵巢浆液性交界性肿瘤(SBOTs)患者保守治疗的结果。方法回顾性分析在我院治疗或转诊的sbot和腹膜植入物患者。 [摘要]journal of Gynecol Cancer, 2022;32(增刊2):A1-A504 - A169 on D, 2022年5月5日。P由赖特保护。http / ijgc。jj.com / nt jgynecol C acer:首次发表于222年12月20日,号10.11ijgc-2022-E S G O .63。我们从
{"title":"2022-RA-160-ESGO Fertility preservation in patients with early cervical cancer after organ-sparing surgery: retrospective monocentric study","authors":"O. P. Matylevich, Ilya A Tarasau, I. Bakinouskaya, Sviatlana Shelkovich","doi":"10.1136/ijgc-2022-esgo.363","DOIUrl":"https://doi.org/10.1136/ijgc-2022-esgo.363","url":null,"abstract":"2022-RA-154-ESGO Figure 1 Histopathologic findings in ovaries of pregnant mice exposed to chemotherapy. (A) Short exposure experiment (sacrifice at GD 15.5). (B) Long exposure experiment (sacrifice at GD 18.5). (C) Overview of normal ovary containing preantral (p: primary, s: secondary), antral (an: antal, an*: antral preovulatory), and atretic (ar) follicles, and corpora lutea (c). (D) Normal preantral follicle. (E) Apoptosis in preantral follicles, arrows indicate apoptotic cells. (F) IHC of Caspase-3 in preantral follicle, arrows indicate positively stained granulosa cells. (G)Necrosis of granulosa cells of the follicle, star indicates area of necrotic cells. Scale bars: C=100 mm, D-F=10 mm, G=20 mm Abstract 2022-RA-154-ESGO Figure 2 Phospho-H2AX Immunohistochemistry of primordial follicles in pregnant mice of short exposure experiment. (A)) Expression versus non-expression of phospho-H2AX in primordial follicles per treatment modality (n = 6 mice in control group and n = 3 mice per chemotherapeutic agent). Examples of staining of primordial follicles in (B) control group (non-expression), (C) carboplatin group (expression), and (D) cyclophosphamide high dose group (expression). Arrows indicate primordial follicles. Scale bar: B-D = 10 mm2022-RA-154-ESGO Figure 2 Phospho-H2AX Immunohistochemistry of primordial follicles in pregnant mice of short exposure experiment. (A)) Expression versus non-expression of phospho-H2AX in primordial follicles per treatment modality (n = 6 mice in control group and n = 3 mice per chemotherapeutic agent). Examples of staining of primordial follicles in (B) control group (non-expression), (C) carboplatin group (expression), and (D) cyclophosphamide high dose group (expression). Arrows indicate primordial follicles. Scale bar: B-D = 10 mm Conclusion Despite physiological ovarian function suppression during gestation, chemotherapy-induced damage of the ovaries occurs in pregnant mouse models, potentially affecting future fertility. 2022-RA-160-ESGO FERTILITY PRESERVATION IN PATIENTS WITH EARLY CERVICAL CANCER AFTER ORGAN-SPARING SURGERY: RETROSPECTIVE MONOCENTRIC STUDY Olga P Matylevich, Ilya A Tarasau, Iryna Y Bakinouskaya, Sviatlana Y Shelkovich. NN Alexandrov National Cancer Centre of Belarus, Minsk, Belarus; Belarusian Medical Academy of Postgraduate Education, Minsk, Belarus 10.1136/ijgc-2022-ESGO.363 Introduction/Background To assess the desire for motherhood, reproductive and obstetric outcomes in young patients with early cervical cancer treated with fertility-sparing surgery (FSS). Methodology All women £ 45 years who underwent FSS for early cervical cancer (stages IA1-IB1) at NN Alexandrov National Cancer Centre of Belarus between January 2010 and December 2020 were retrospectively identified. Fertility-sparing options included cold knife conization (CKC) in 46 patients, CKC and pelvic lymph node dissection (PLND) – in 12, abdominal radical trachelectomy (ART) – in 46, and laparoscopic radical trachelecto","PeriodicalId":292924,"journal":{"name":"Fertility/Pregnancy","volume":"109 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2022-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"115119400","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
期刊
Fertility/Pregnancy
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1