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2021 IEEE National Biomedical Engineering Conference (NBEC)最新文献

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Analyzing the Texture of Nakagami Parametric Images for Classification of Breast Cancer 用于乳腺癌分类的Nakagami参数图像纹理分析
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618762
Sabiq Muhtadi, A. Chowdhury, Rezwana R Razzaque, Ahmad Shafiullah
In this paper we analyze the capability of texture features extracted from Nakagami parametric images for the classification of breast cancer. Nakagami parametric maps were generated from ultrasound envelope images using a sliding window of length 0.75mm and 0.0385mm increment (95% overlap). Next, Gray Level Co-occurrence Matrix (GLCM) techniques were applied to the parametric maps in order to extract texture features. These texture features were utilized for the classification of breast lesions. An Area under the Receiver Operating Characteristics curve (AUC) of 0.90 and a sensitivity of 88.5% was obtained, suggesting that texture features derived from Nakagami parametric images have the potential to play an important role in the early diagnosis of breast cancer.
本文分析了从Nakagami参数图像中提取的纹理特征用于乳腺癌分类的能力。采用长度为0.75mm和增量为0.0385mm的滑动窗口(95%重叠),从超声包膜图像中生成Nakagami参数图。其次,将灰度共生矩阵(GLCM)技术应用于参数映射,提取纹理特征;这些纹理特征被用于乳腺病变的分类。受试者工作特征曲线下面积(Area under Receiver Operating characteristic curve, AUC)为0.90,灵敏度为88.5%,表明基于Nakagami参数图像的纹理特征在乳腺癌早期诊断中具有重要的应用价值。
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引用次数: 2
Investigation on Properties of Capnogram: On Stationarity and Spectral Components of the Signal 图的性质研究——关于信号的平稳性和谱分量
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618746
Mushikiwabeza Alexie, M. Malarvili
Capnography provides a graphical representation of the CO$_{mathbf{2}}$ concentration in the exhaled gases. There are different methods that are used to extract time domain features of capnogram. However, those methods are manual and only suitable for normal and asthmatic capnograms. Frequency domain method is mostly used to analyze physiological signals, by assuming that those signals are stationary. Note that numerous physiological phenomena are characterized by dynamical properties. Identifying the nature of the signal is a preliminary stage which can enable to select suitable signal processing method. In this study, stationarity of capnogram signal was tested by analyzing statistical characteristics of the time series of the carbon dioxide samples recorded from normal subjects, and patients with complaint of asthma, chronic obstructive pulmonary disease, and pulmonary edema. Analysis of the spectral components of capnogram was performed using Fourier transform. The results show that there is a slight change in the statistical properties of the time series. Suggesting that capnogram can be considered as a quasi-stationary signal. Besides, analysis of capnogram based on the number of main lobes and side lobes can help to examine how changes in the spectral properties of capnogram relates to the respiratory status of the person, which can subsequentially help to discriminate normal from abnormal capnograms, and thus classify different respiratory diseases. This study may provide the key insight while identifying the proper signal processing method to analyze capnogram waveform.
二氧化碳记录仪提供了呼出气体中CO$_{mathbf{2}}$浓度的图形表示。提取脑电图的时域特征有不同的方法。然而,这些方法是手工的,只适用于正常和哮喘的心电图。频域方法主要用于生理信号的分析,它假定生理信号是平稳的。注意,许多生理现象都具有动力学特性。识别信号的性质是选择合适的信号处理方法的基础。本研究通过分析正常受试者、哮喘、慢性阻塞性肺疾病和肺水肿患者记录的二氧化碳样本时间序列的统计特征,检验二氧化碳图信号的平稳性。利用傅里叶变换对图像的频谱成分进行分析。结果表明,时间序列的统计性质有轻微的变化。提示脑电图可视为准平稳信号。此外,基于主叶数和侧叶数对脑脑图进行分析,可以考察脑脑图频谱特性的变化与人的呼吸状态的关系,从而有助于区分脑脑图的正常与异常,从而对不同的呼吸系统疾病进行分类。本研究可能为确定合适的信号处理方法来分析脑电图波形提供关键的见解。
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引用次数: 0
An Explainable AI powered Early Warning System to address Patient Readmission Risk 一个可解释的人工智能驱动的早期预警系统,以解决患者再入院风险
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618766
Tanusree De, Ahmeduvesh Mevawala, Ramyasri Nemani
Hospital readmission is undesirable for all the involved parties, the patient, the hospital and the insurer. Readmission put patients at-risk for hospital acquired infections, medical errors and unfavorable outcomes. For hospitals, it leads to a gradual increase in operating expenses. For payers, readmission means additional cost. So, predicting the possibility of patient readmission is very critical and highly relevant for all the parties involved. There are powerful machine learning algorithms, like Random Forest, XGBoost, Neural Net that can be used to develop the predictive model to predict the probability of patient readmission. However, these models are all black box; they can give the prediction with high accuracy; however, they do not explain how they arrived at the prediction. Herein comes the role of Explainable AI. In this paper, we have developed a novel model-specific local explanation methodology to derive explanation at an individual patient level, considering the inner learning process of a Random-Forest model. The derived explanations from proposed methodology are human-interpretable irrespective of the complexities of the underlying Random-Forest model and the explanations provide guidance to the doctor for prescribing the necessary remedy to the patient to prevent him/her from readmission within thirty days of discharge.
再入院对所有相关方,病人、医院和保险公司来说都是不可取的。再入院会使患者面临医院获得性感染、医疗差错和不良后果的风险。对于医院来说,这导致了运营费用的逐渐增加。对于付款人来说,重新入学意味着额外的费用。因此,预测病人再入院的可能性对所有相关方来说都是非常关键和高度相关的。有强大的机器学习算法,比如随机森林,XGBoost,神经网络,可以用来开发预测模型来预测病人再入院的概率。然而,这些模型都是黑盒子;它们可以给出高精度的预测;然而,他们没有解释他们是如何得出这一预测的。这就是可解释人工智能的作用。在本文中,我们开发了一种新的模型特定的局部解释方法,考虑随机森林模型的内部学习过程,在个体患者水平上推导解释。无论潜在的随机森林模型的复杂性如何,从所提出的方法中得出的解释都是人类可解释的,并且这些解释为医生提供了指导,以便为患者开出必要的治疗处方,以防止他/她在出院后30天内再次入院。
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引用次数: 0
Design and analysis of interbody fusion cage materials based on finite element analysis 基于有限元分析的椎间融合笼材料设计与分析
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618720
N. Nizam, M. Mazlan, N. Salleh, Muhammad Anas Razali, A. H. Abdullah, M. H. Jalil, H. Takano, Nur Dalilah Diyana Nordin
This study investigates the effect of the Posterior Lumbar Interbody Fusion (PLIF) cage’s material on the strength and stability of the cage. The lumbar vertebrae L2-L3 unit finite element model was developed from computed tomography (CT) scan images in 3D Slicer software. The PLIF cage model was constructed using Solidworks software. The models were assigned with polyetheretherketone (PEEK) and polylactic acid (PLA) materials. The models were implanted and analyzed in Ansys Workbench Software by applying external preload, compression load and other load conditions to mimic the spine physiological motions under static and dynamic analysis. The von Mises stress and maximum principal stress were observed and analyzed to evaluate their strength and stability. In addition, the percentage differences between the von Mises stress and yield strength of the material and between the maximum principal stress and critical strength of the material were calculated. The PEEK cage produced higher von Mises stresses than the PLA cage for the static analysis. However, the PEEK cage exhibited lower percentage differences than the PLA cage. This result indicates that the PEEK cage has the superior structural integrity to the PLA interbody cage. The results from the dynamic analysis showed that both cages exhibited extremely low von Mises stresses and similar curve patterns. These results indicate that both cages are stable and do not pose harmful health implications. Thus, PLA can be considered an alternative material for the cage because it is more cost-effective than the PEEK material, and stresses generated were far lower than the ultimate tensile strength and yield strength of the material.
本研究探讨了后路腰椎椎体间融合器(PLIF)的材料对其强度和稳定性的影响。腰椎L2-L3单元有限元模型是在3D Slicer软件中从计算机断层扫描(CT)图像中建立的。利用Solidworks软件构建PLIF笼模型。模型分别使用聚醚醚酮(PEEK)和聚乳酸(PLA)材料。在Ansys Workbench软件中植入模型并进行分析,分别施加外部预载荷、压缩载荷等载荷条件,模拟脊柱在静态和动态分析下的生理运动。观察并分析了von Mises应力和最大主应力,以评价其强度和稳定性。此外,计算了材料的von Mises应力与屈服强度、最大主应力与临界强度之间的百分比差值。静态分析中PEEK笼比PLA笼产生更高的von Mises应力。然而,PEEK笼比PLA笼表现出更低的百分比差异。这一结果表明PEEK保持架具有优于PLA体间保持架的结构完整性。动态分析结果表明,两种网箱均表现出极低的von Mises应力和相似的曲线模式。这些结果表明,这两个笼子都是稳定的,不会对健康造成有害影响。因此,PLA可以被认为是保持架的替代材料,因为它比PEEK材料更具成本效益,并且产生的应力远低于材料的极限抗拉强度和屈服强度。
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引用次数: 1
P300 Somatosensory Validation of Vibrotactile Haptic Feedback for Upper Limb Prosthesis P300上肢假体振动触觉反馈的体感验证
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618709
Nur Amalina Has, M. N. Jamaludin, Sujana Mohd Rejab, Zulkifli Ahmad, Nurul Farha Zainuddin, A. H. Abdul Salam, Chu Ai Reen, M. A. As’ari
Haptic sensation research based on the event’s related potential (ERP) has been carried out extensively in order to help amputees to be able feel and control their prosthetic hand. Clinically, somatosensory evoked potential is suggested in the pain-related evoked potential and able to control a computer using a brain to computer interface system called BCI. Somatosensory response can be evoked by tactile vibrators whether it is directly and indirect contact with skin. Somatosensory evoked potential has been reported to have lower signal to noise ratio compared to the common visual evoked potential. P300 based on somatosensory evoked potential were discovered as a benchmark that a person will generate P300 whenever decision making as simple as lift their finger take place. The aim of this paper is to identify the best location of the upper limb for tactile haptic placement and investigating whether the vibration motor haptic tactile setup reflect on the P300 somatosensory response from encephalography recordings. Results show that most of the subjects correctly guesses during upper arm position of haptic tactile feedback than the lower arm position. The vibration motor haptic tactile feedback setup was validated via experiment with mental task in order to elicit P300 somatosensory event related potential (ERP).
基于事件相关电位(ERP)的触觉研究已经广泛开展,以帮助截肢者能够感觉和控制他们的假手。在临床上,躯体感觉诱发电位被认为是与疼痛相关的诱发电位,并且能够通过脑机接口系统(BCI)控制计算机。无论是与皮肤直接接触还是间接接触,触觉振动器都能诱发体感反应。据报道,体感诱发电位与普通视觉诱发电位相比具有较低的信噪比。基于体感诱发电位的P300被发现是一个基准,每当人们做出像举起手指这样简单的决定时,就会产生P300。本文的目的是确定上肢触觉放置的最佳位置,并研究振动运动触觉设置是否反映了脑电图记录的P300体感反应。结果表明:上臂位置对触觉反馈的猜测正确率高于下臂位置。通过心理任务实验,验证了振动马达触觉触觉反馈设置诱发P300体感事件相关电位(ERP)。
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引用次数: 0
Development of Hip Implant: Gait Study and Finite Element Analysis 髋关节植入物的发展:步态研究和有限元分析
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618708
Iman Nur Alissa Md Rosli, S. Shuib, A. Shokri, A. Ghani, Najwa Syakirah Hamizan, Iffa Mohd Arrif
The hip joint gives stability to the whole human structure making it an important part of the human body that provides the ability to carry out various everyday work such as walking and running. Although hip joint replacement is commonly and successfully performed, an increased number of younger and active patients widens the range of motion of patients leading to the need for a longer lifetime of the replacement joint. This matter puts a challenge to the orthopedic surgical procedures that is needed to be overcome. This paper studies the effect of gait activity and loading acting across the joint by using Finite Element Analysis (FEA) to evaluate the total deformation and von Mises stress distribution of the hip implant. Alongside, structural analysis is conducted to evaluate a better implant design that has less stress distribution which is lesser than its yielded strength to avoid implant failure. FEA was performed using Computer-Aided Engineering (CAE) software of ANSYS by static structural analysis to study the mechanical behaviors of 3-dimensional hip implant models with the femoral design being loaded with forces ranging from 2.5 to 6.4 kN. Obtained results show von Mises stress distribution ranging from 400-1000 MPa of different gait activities, most cases are notably lower than the yield stress value of titanium alloy, Ti-6Al-4V (860 MPa). This work revealed the critical stress concentration located on the hip implant by numerical analysis with lesser stress values than the yielded strength that offers to improve optimization of implant design and life expectancy to avoid the hip implant revision in active patients.
髋关节为整个人体结构提供了稳定性,使其成为人体的重要组成部分,提供了进行各种日常工作的能力,如走路和跑步。尽管髋关节置换术很常见,也很成功,但越来越多的年轻和活跃的患者扩大了患者的活动范围,导致需要更长的置换关节寿命。这一问题对矫形外科手术提出了一个需要克服的挑战。本文通过有限元分析(Finite Element Analysis, FEA)评估髋关节假体的总变形和von Mises应力分布,研究步态活动和载荷作用在关节上的影响。此外,还进行了结构分析,以评估更好的种植体设计,其应力分布小于其屈服强度,以避免种植体失效。采用ANSYS计算机辅助工程(CAE)软件进行静力结构分析,研究股骨设计的三维假体模型在载荷范围为2.5 ~ 6.4 kN时的力学行为。所得结果表明,不同步态活动的von Mises应力分布范围在400-1000 MPa之间,大多数情况下均明显低于钛合金Ti-6Al-4V的屈服应力值(860 MPa)。这项工作通过数值分析揭示了位于髋关节假体上的临界应力集中,其应力值小于屈服强度,从而改善了假体设计的优化和预期寿命,避免了活动期患者髋关节假体翻修。
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引用次数: 0
Association of Hand Grip and Pinch Strength Reading with Nutritional Health Status Among Orang Asli in Perak, Malaysia 马来西亚霹雳州原住民的握力和握力读数与营养健康状况的关系
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618765
S. Usman, F. Rusli, N. Noor, S. A. M. Aris, M. N. Muhtazaruddin, Sharifah Alwiah Syed Abd Rahman, N. Bani
Malaysian indigenous people, locally known as Orang Asli, live in remote forest areas for centuries and rely heavily on agriculture for their daily subsistence. The association of nutritional status with hand grip and pinch strength readings among adults in Orang Asli community is investigated in this preliminary study. The nutritional status of the participants, as well as their hand grip and pinch strength, are assessed using a cross-sectional design. Patients who are malnourished or at risk of malnutrition are identified using a validated nutritional risk screening, also known as the Malnutritional Universal Screening Tool (MUST). An independent t-test compares the means of the hand grip and pinch strength readings with MUST risk group. A p-value of 0.05 or less is considered statistically significant. It is evident that there is a similar of hand grip and pinch strength reading between medium and high risk group of MUST score.
马来西亚土著居民,在当地被称为Orang Asli,几个世纪以来一直生活在偏远的森林地区,严重依赖农业来维持日常生活。在这项初步研究中,调查了奥朗阿斯利社区成年人的营养状况与握力和握力读数的关系。参与者的营养状况,以及他们的握力和握力,使用横断面设计进行评估。使用经过验证的营养风险筛查(也称为营养不良普遍筛查工具(MUST))来确定营养不良或有营养不良风险的患者。独立t检验比较了MUST风险组的握力和捏力读数。p值小于等于0.05被认为具有统计学意义。MUST评分中、高危组的握力、握力读数明显相似。
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引用次数: 0
Relationship of Backpack Weight Towards Risk Factor for Scoliosis Among Primary School Children in Pahang, Malaysia 背包重量与马来西亚彭亨市小学生脊柱侧凸危险因素的关系
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618722
Ahmad Aizat Che Rahmat, S. A. Jalil, Sharifah Alwiah Syed Abd Rahman, S. Usman
The purpose of this study is to determine the relationship of backpack weight and risk factor for scoliosis in primary school children. The risk factors are identified by age, gender, body mass index and the weight of the backpack. A total of 260 children aged from 7 to 12 years old participated in this study. The test was performed by measuring the angle of trunk rotation (ATR) on Adam Forward Bending Test (AFBT) using a scoliometer. ATR readings at 5 ° and above is deemed to be positive. The findings showed that a significant of moderately correlation was found on risk factor of age (r = 0.538), gender (r = 0.580), and backpack weight (r = 0.552) which indicates that age, gender and backpack weight may contribute to risk factor of scoliosis.
本研究旨在探讨小学生背包重量与脊柱侧凸危险因素的关系。危险因素由年龄、性别、身体质量指数和背包的重量确定。共有260名7 - 12岁的儿童参与了本研究。试验采用脊柱侧弯计测量Adam前弯试验(AFBT)中躯干旋转角(ATR)。5°及以上的ATR读数被认为是正的。结果显示,年龄(r = 0.538)、性别(r = 0.580)、背包重量(r = 0.552)与脊柱侧凸的危险因素存在显著的中度相关,提示年龄、性别和背包重量可能是脊柱侧凸的危险因素。
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引用次数: 1
Frequency Detection Of Hand Tremors Using Customized Accelerometer 基于定制加速度计的手部振动频率检测
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618761
A. Al-Kazwini, Ahmad Halilah, Aeshah Hendi, Ibrahim Al-Saeed, Abdullah Al-Azamat, W. Al-Zyoud
Tremor can be defined as involuntary, rhythmic muscle contraction involving movements of one or more body parts, e.g. hands, arms, head, face, voice, trunk, and legs. This work aims to measure the frequency of hand tremors using a customized, reasonably accurate method to monitor the severity of tremors and reach a point where building hand tremors stabilizing system is possible to allow patients to overcome this problem. The data in this work was collected using an accelerometer attached to the patient’s index finger as it is involved in important daily life activities such as writing. The signal was obtained using a microcontroller and an Arduino Mega and has been processed using MATLAB software from Math Works, combined with an open-source Arduino Software, an Integrated Development Environment (IDE). The proposed method was applied to 30 patients with hand tremors from various diseases compared with a normal person as a source for a normal signal. The maximum frequency of hand tremors was around 7 Hz, which is in agreement with previous studies. We conclude that this technique can handle and measure very low tremor frequencies, which can be utilized in the future for building a tremor stabilizing device.
震颤可以定义为不自主的、有节奏的肌肉收缩,包括一个或多个身体部位的运动,如手、手臂、头、脸、声音、躯干和腿。这项工作的目的是通过定制的、合理准确的方法来测量手部震颤的频率,以监测震颤的严重程度,并达到建立手部震颤稳定系统的目的,使患者能够克服这一问题。这项工作的数据是通过连接在患者食指上的加速度计收集的,因为它参与了重要的日常生活活动,如写作。该信号使用微控制器和Arduino Mega获得,并使用Math Works中的MATLAB软件,结合开源的Arduino软件,集成开发环境(IDE)进行处理。将该方法应用于30名不同疾病的手部震颤患者,并与正常人进行比较,作为正常信号的来源。手部震颤的最大频率约为7赫兹,这与之前的研究一致。我们的结论是,这种技术可以处理和测量非常低的震颤频率,这可以在未来用于建立震颤稳定装置。
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引用次数: 0
Automated Paralysis Patient Monitoring System 自动麻痹病人监测系统
Pub Date : 2021-11-09 DOI: 10.1109/nbec53282.2021.9618721
M. Vijay Kumar, Kaythry Pandurangan, R. Vinu
Paralytic people in most cases are not able to convey their needs as they are neither able to speak properly nor do they convey through sign language due to loss in motor control by their brain. In such a situation, our proposed system helps the disabled person in displaying a message over the LCD by simple motion of their hand. The proposed system works by reading the various tilt directions of the hand. The transmitter is attached to a glove which is worn by patient. User just needs to tilt the device in different directions to convey different messages. An accelerometer is used to measure the statistics of motion. It then passes on this data to the microcontroller which processes the data and displays the particular message as per the input obtained. It sounds a buzzer along with the message as soon as it receives motion signal from the accelerometer. The data is then transmitted online to IOT Adafruit server and the message is displayed online. With the help of this system, the patients affected by paralysis can convey their important needs to others.
在大多数情况下,瘫痪的人无法表达他们的需求,因为他们既不能正常说话,也不能通过手语表达,因为他们的大脑失去了运动控制。在这种情况下,我们提出的系统可以帮助残疾人通过简单的手部动作在LCD上显示信息。该系统通过读取手的不同倾斜方向来工作。发射器附在病人戴的手套上。用户只需要将设备倾斜不同的方向来传达不同的信息。加速度计用于测量运动的统计量。然后,它将这些数据传递给处理数据的微控制器,并根据所获得的输入显示特定的消息。一旦接收到加速度计的运动信号,它就会发出蜂鸣声和信息。然后将数据在线传输到IOT Adafruit服务器,并在线显示消息。在这个系统的帮助下,瘫痪患者可以向他人传达他们的重要需求。
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引用次数: 0
期刊
2021 IEEE National Biomedical Engineering Conference (NBEC)
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