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Venous thromboembolic complications in patients with severe and extremely severe COVID-19 重症和极重症COVID-19患者的静脉血栓栓塞并发症
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202104141
M. V. Bychinin, I. Mandel, T. Klypa, P. Avdonin, D. I. Korshunov, T.S. Bobrovitskaya, S. A. Andreichenko
Objective. To analyze the incidence and predictors of venous thromboembolic complications (VTEC) in COVID-19 patients ad-mitted to intensive care unit (ICU). Material and methods. A retrospective study recruited 200 ICU patients presenting with severe or critical COVID-19. Results. VTEC were found in 67 (33.5%) out of 200 patients. In 63 patients, deep and superficial vein thrombosis was observed. Four patients had pulmonary embolism. In 41 (20.5%) patients, VTEC occurred within the first day after admission to ICU. Patients presenting with VTEC had more extensive lung damage (CT data) and more common need for vasopressors (79.1% vs 59.4%, p=0.005) and mechanical ventilation (89.6% vs 60.2%, p=0.0001). Survival of these patients was lower (23 (34.3%) vs 76 (57.1%), p=0.003). There were significant differences in levels of von Willebrand factor antigen (vWF: Ag), interleukin 6 (IL-6), antithrombin III (AT III) and protein C. According to ROC analysis, vWF: Ag above 455% (AUC — 0.852 (0.69;1.00), p=0.008) was highly predictive for the risk of VTEC after 1 and 7 days. AT III below 72% (AUC — 0.77 (0.55;0.99), p=0.04) and IL-6 above 256 pg/ml (AUC — 0.85 (0.65;1.00), p=0.053) were prognostic factors of VTEC after the first day. Protein C below 81.5% at admission (AUC — 0.79 (0.59-0.99), p=0.042) was predictive regarding VTEC by the seventh day. Conclusion. Incidence of VTEC in ICU patients was 33.5%. In 60% of patients, VTEC developed before admission to ICU. vWF: Ag, AT III, IL-6, and protein C serve as predictors of VTEC in patients with severe or critical COVID-19. © 2021, Media Sphera Publishing Group. All rights reserved.
目标。目的分析2019冠状病毒病疫情(COVID-19)重症监护病房(ICU)患者静脉血栓栓塞并发症(VTEC)的发生率及预测因素。材料和方法。一项回顾性研究招募了200名重症或危重型COVID-19 ICU患者。结果。200例患者中有67例(33.5%)出现VTEC。63例患者出现深、浅静脉血栓形成。4例患者有肺栓塞。41例(20.5%)患者在入住ICU后第一天内发生VTEC。出现VTEC的患者有更广泛的肺损伤(CT数据),更需要血管加压剂(79.1% vs 59.4%, p=0.005)和机械通气(89.6% vs 60.2%, p=0.0001)。这些患者的生存率较低(23例(34.3%)vs 76例(57.1%),p=0.003)。血管性血友病因子抗原(vWF: Ag)、白细胞介素6 (IL-6)、抗凝血酶III (AT III)、蛋白c水平差异有统计学意义。ROC分析显示,vWF: Ag在455%以上(AUC - 0.852 (0.69;1.00), p=0.008)对第1、7天发生VTEC的风险具有高度预测作用。atiii低于72% (AUC - 0.77 (0.55;0.99), p=0.04)、IL-6高于256 pg/ml (AUC - 0.85 (0.65;1.00), p=0.053)是第1天后VTEC的预后因素。入院时蛋白C低于81.5% (AUC - 0.79 (0.59-0.99), p=0.042)可预测第7天的VTEC。结论。ICU患者VTEC发生率为33.5%。60%的患者在进入ICU前出现VTEC。vWF: Ag、AT III、IL-6和蛋白C可作为重型或危重型COVID-19患者VTEC的预测指标。©2021,Media Sphera出版集团。版权所有。
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引用次数: 2
Clinical risks in intensive care unit: how are things with enteral nutrition? 重症监护病房的临床风险:肠内营养情况如何?
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202202180
I. Pasechnik, A. Shchuchko, E. Skobelev
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引用次数: 1
Artificial intelligence and machine learning in intensive care unit 重症监护病房的人工智能和机器学习
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202104197
T. Ramaniuk, D.Yu. Pozdnyakov, F. Mushenok
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引用次数: 0
Effectiveness of general and regional anesthesia for dermatolipofascioectomy in patients with upper limb swelling following mastectomy 全身和区域麻醉对乳房切除术后上肢肿胀患者皮脂筋膜切除术的疗效
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202204166
P. Khudyakov, A. Potapov
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引用次数: 3
Choosing the right statistical test 选择正确的统计检验
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202103188
A. Kuzovlev, M. Yadgarov, L. Berikashvili, E. Ryabova, D.D. Goncharova, S. N. Perehodov, V. Likhvantsev
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引用次数: 13
Lung ultrasound in the intensive care unit of the perinatal centre 围产期中心重症监护病房的肺部超声检查
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202205167
E. A. Mishina, I. V. Ivanova, A.Yu. Pykhova, A.Yu. Trubitsyna, V. O. Bushuev
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引用次数: 1
Cardiac protective properties of lidocaine as adjuvant component of general anesthesia in thoracic surgery for cancer 利多卡因辅助全身麻醉在胸腔肿瘤手术中的心脏保护作用
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202301139
E. Aleksandrova, V. Khoronenko, A. Malanova, Yu.S. Zakharenkova, P. Suvorin
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引用次数: 0
The physician studying philosophy is equal to gods 研究哲学的医生堪比神明
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology2021031110
Ph.M. Shvetskiy, V. I. Potievskaya
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引用次数: 0
Perioperative management of patients with heart failure 心衰患者围手术期的处理
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology20210316
I. Zabolotskikh, A. Bautin, M. Zamyatin, K. M. Lebedinskii, V. I. Potievskaya, N. Trembach
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引用次数: 8
Prediction of septic shock outcome in children requiring extracorporeal hemocorrection 需要体外血液矫正的儿童感染性休克结果的预测
Pub Date : 1900-01-01 DOI: 10.17116/anaesthesiology202206144
Y. Aleksandrovich, K. V. Serednyakov, V. Rybyanov, K. V. Pshenisnov
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引用次数: 2
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Anesteziologiya i reanimatologiya
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