Chemical reduction of organic azides is a commonly accepted route in synthetic organic chemistry to prepare amino compounds. Researchers and scientists are interested in choosing greener pathways in the course of the synthesis of organic molecules. In the present work we report the synthesis of benzene sulphonamide by the electrochemical reduction of benzene sulphonyl azide using platinum electrodes. Influence of current density and voltage, effect of electrolytes, effect of solvents and effect of substrate concentration on the yield of the product have been studied. The reaction is more feasible in the presence of sodium ascorbate (in 1:1 methanol-water) which acts as both supporting electrolyte and electron transferring agent in the electrochemical process.
{"title":"Electrochemical conversion of benzene sulphonyl azide into sulphonamide assisted by sodium ascorbate","authors":"","doi":"10.56042/ijc.v62i9.5381","DOIUrl":"https://doi.org/10.56042/ijc.v62i9.5381","url":null,"abstract":"Chemical reduction of organic azides is a commonly accepted route in synthetic organic chemistry to prepare amino compounds. Researchers and scientists are interested in choosing greener pathways in the course of the synthesis of organic molecules. In the present work we report the synthesis of benzene sulphonamide by the electrochemical reduction of benzene sulphonyl azide using platinum electrodes. Influence of current density and voltage, effect of electrolytes, effect of solvents and effect of substrate concentration on the yield of the product have been studied. The reaction is more feasible in the presence of sodium ascorbate (in 1:1 methanol-water) which acts as both supporting electrolyte and electron transferring agent in the electrochemical process.","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"30 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135203340","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
A novel, repeatable, and swift kinetic approach for determining alpha-lipoic acid (ALA) in sodium lauryl sulfate (SLS) micellar medium has been presented, and it has been connected to ALA determination in drug formulations. The approach is based on ALA inhibitory property. ALA (containing two sulfur atoms) forms a chelate with Pd2+, lowering the effective [Pd(II)], and ultimately, the Pd2+ catalyzed cyanide substitution rate from [Fe(CN)6]4- by 4-cyanopyridine (4-CNpy). Fixed times of 5 and 10 minutes were chosen under optimal reaction conditions with [4-CNpy] = 2.0 × 10-3 mole dm-3, pH = 3.50 ± 0.02, Temp = 298 ± 0.2 K, I = 0.1 mole dm-3 (NaClO4), [Fe(CN)64-] = 1.25 × 10-4 mole dm-3, [Pd+2] = 6.0 × 10-5 mole dm-3, and [SLS] = 7.75 × 10-3 mole dm-3 to calculate the absorbance at 477 nm associated with the final substitution product [Fe(CN)5 4-CNpy]3-. ALA's inhibiting influence on the Pd2+ catalyzed cyanide substitution with 4-CNpy from [Fe(CN)6]4-, has been represented by a modified mechanistic approach. The concentration of ALA in various water specimens can be measured at the micro-level down to 1.0 × 10-6 mole dm-3 using the established kinetic spectrophotometric approach. The suggested method is highly reproducible and has been effectively applied to accurately quantify the ALA in pharmaceutical samples. Even as much as 1000 with [ALA], typical additives used in medications do not significantly hinder the determination of ALA.
{"title":"Determination of alpha-lipoic acid in pharmaceutical samples using inhibitory kinetic approach in SLS micellar medium","authors":"","doi":"10.56042/ijc.v62i9.2574","DOIUrl":"https://doi.org/10.56042/ijc.v62i9.2574","url":null,"abstract":"A novel, repeatable, and swift kinetic approach for determining alpha-lipoic acid (ALA) in sodium lauryl sulfate (SLS) micellar medium has been presented, and it has been connected to ALA determination in drug formulations. The approach is based on ALA inhibitory property. ALA (containing two sulfur atoms) forms a chelate with Pd2+, lowering the effective [Pd(II)], and ultimately, the Pd2+ catalyzed cyanide substitution rate from [Fe(CN)6]4- by 4-cyanopyridine (4-CNpy). Fixed times of 5 and 10 minutes were chosen under optimal reaction conditions with [4-CNpy] = 2.0 × 10-3 mole dm-3, pH = 3.50 ± 0.02, Temp = 298 ± 0.2 K, I = 0.1 mole dm-3 (NaClO4), [Fe(CN)64-] = 1.25 × 10-4 mole dm-3, [Pd+2] = 6.0 × 10-5 mole dm-3, and [SLS] = 7.75 × 10-3 mole dm-3 to calculate the absorbance at 477 nm associated with the final substitution product [Fe(CN)5 4-CNpy]3-. ALA's inhibiting influence on the Pd2+ catalyzed cyanide substitution with 4-CNpy from [Fe(CN)6]4-, has been represented by a modified mechanistic approach. The concentration of ALA in various water specimens can be measured at the micro-level down to 1.0 × 10-6 mole dm-3 using the established kinetic spectrophotometric approach. The suggested method is highly reproducible and has been effectively applied to accurately quantify the ALA in pharmaceutical samples. Even as much as 1000 with [ALA], typical additives used in medications do not significantly hinder the determination of ALA.","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-09-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"135203121","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Quantum chemical and third order nonlinear optical investigation of (E)-1-(1H-imidazol-1-yl)-3-(1H-indol-2-yl)prop-2-en-1-one","authors":"","doi":"10.56042/ijc.v62i8.198","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.198","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"47860249","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Design and synthesis of new tricyclic quinoline derivatives from intramolecular cyclization of benzylidene malonic derivatives","authors":"","doi":"10.56042/ijc.v62i8.4795","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4795","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"1 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41410245","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Convergent and efficient synthesis of 1,2,4-triazolo[5,1-b]quinazolin-8-ones using copper incorporated hydroxyapatite encapsulated Kit-6 as a recoverable nanocatalyst","authors":"","doi":"10.56042/ijc.v62i8.4776","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4776","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43462882","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Electrochemically induced an efficient, simple, non-catalytic synthesis of β-phosphonomalonates via multicomponent reaction","authors":"","doi":"10.56042/ijc.v62i8.478","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.478","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45981707","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Bimetallic quantum dots (Cu-Pd, Ni-Pd) catalyzed reaction of bromo arenes with alkenes and aryl boronic acids","authors":"","doi":"10.56042/ijc.v62i8.4769","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4769","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"42653296","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. S. Birajdar, A. Deshmukh, A. Kumbharkhane, B. Suryawanshi
.
{"title":"Study of co-operative dynamics and thermo-dielectric parameters of n-butyl acetate-xylene solutions using dielectric spectroscopy","authors":"S. S. Birajdar, A. Deshmukh, A. Kumbharkhane, B. Suryawanshi","doi":"10.56042/ijc.v62i8.4794","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4794","url":null,"abstract":".","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"45675629","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
The synthesis, spectral characterization, single crystal structure and properties of a new potassium coordination polymer [K(LH2)(MoO4)] 1 (LH2 = 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium) are reported. The bimetallic compound 1 crystallizes in the non-centrosymmetric trigonal P3c1 space group with K+, (LH2)+ and (MoO4)2– located on three-fold axes. The K+ ion exhibits hexa coordination and both (LH2)+ and (MoO4)2– function as µ3-bridging tridentate ligands resulting in the formation of a three-dimensional (3D) polymeric structure. In the 3D polymer, the {KO6} octahedra and {MoO4} tetrahedra are interlinked into a hexagonal array of alternating {KO6} and {MoO4} polyhedra connected via corner-sharing with enclosure of (LH2)+ ion in the cavity. The (LH2)+ and (MoO4)2– units in 1 are interlinked with the aid of three varieties of hydrogen bonding interactions. Thermal decomposition of 1 at 600°C results in the formation of K2Mo2O7. Comparative structural chemistry of several (LH2)+ containing compounds is described.
{"title":"Synthesis, structure characterization, and properties of a new heterometallic coordination polymer containing two μ3-bridging tridentate ligands","authors":"","doi":"10.56042/ijc.v62i8.4779","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4779","url":null,"abstract":"The synthesis, spectral characterization, single crystal structure and properties of a new potassium coordination polymer [K(LH2)(MoO4)] 1 (LH2 = 1,3-dihydroxy-2-(hydroxymethyl)propan-2-aminium) are reported. The bimetallic compound 1 crystallizes in the non-centrosymmetric trigonal P3c1 space group with K+, (LH2)+ and (MoO4)2– located on three-fold axes. The K+ ion exhibits hexa coordination and both (LH2)+ and (MoO4)2– function as µ3-bridging tridentate ligands resulting in the formation of a three-dimensional (3D) polymeric structure. In the 3D polymer, the {KO6} octahedra and {MoO4} tetrahedra are interlinked into a hexagonal array of alternating {KO6} and {MoO4} polyhedra connected via corner-sharing with enclosure of (LH2)+ ion in the cavity. The (LH2)+ and (MoO4)2– units in 1 are interlinked with the aid of three varieties of hydrogen bonding interactions. Thermal decomposition of 1 at 600°C results in the formation of K2Mo2O7. Comparative structural chemistry of several (LH2)+ containing compounds is described.","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":"2 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"136337119","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Basic Red 9 dye encapsulated graphene oxide-montmorillonite composite: Fluorescent and electrochemical sensor for dopamine in presence of ascorbic acid and uric acid","authors":"","doi":"10.56042/ijc.v62i8.4767","DOIUrl":"https://doi.org/10.56042/ijc.v62i8.4767","url":null,"abstract":"","PeriodicalId":29765,"journal":{"name":"INDIAN JOURNAL OF CHEMISTRY","volume":" ","pages":""},"PeriodicalIF":0.0,"publicationDate":"2023-08-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"43758597","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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