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[Heparin-induced thrombocytopenia Type II (HIT II) A fatal complication of heparin use for thromboembolism prevention]. [肝素诱导的II型血小板减少症(HIT II):肝素用于预防血栓栓塞的致命并发症]。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
G Hobbensiefken, B Driller, V Studtmann, K Kunz, G Lehrbach

Heparin-induced thrombocytopenia type II (HIT II) is the most severe complication during prophylactic treatment with low doses of heparin. Five cases demonstrate the life-threatening consequences of this immune-mediated thromboembolic disease. In order to improve prognosis it is most important to start therapy just before diagnosis is assured by laboratory tests. First choice treatment is the low-molecular-weight heparinoid Orgaran. In patients with an episode of HIT II both low-molecular-weight heparin and unfractionated heparin will be contraindicated for a life time.

肝素诱导的II型血小板减少症(HIT II)是低剂量肝素预防性治疗中最严重的并发症。五个病例证明了这种免疫介导的血栓栓塞性疾病的危及生命的后果。为了改善预后,最重要的是在实验室检查确定诊断之前开始治疗。首选的治疗方法是低分子类肝素器官。在HIT II发作的患者中,低分子肝素和未分离肝素终身禁忌症。
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引用次数: 0
[Autologous keratinocyte culture on hyaluronic acid ester membranes: an alternative in complicated wound management?]. 透明质酸酯膜上的自体角质细胞培养:复杂伤口处理的一种选择?
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
D Hollander, M Stein, A Bernd, J Windolf, R Wagner, A Pannike

Cultivation and transplantation of autologous keratinocytes has been used in the last 15 years to treat complicated wounds of different origin. In spite of excellent technical advancements and clinical experiences cultured keratinocyte grafting still is associated with practical limitations. Application of hyaluronic acid ester membranes as carrier substrate for the transfer of keratinocytes allows improved graft handling: reduces total time required for tissue cultivation and furthermore enhances vitality of the keratinocytes because of possible grafting at semiconfluence.

在过去的15年中,自体角质形成细胞的培养和移植已被用于治疗不同来源的复杂伤口。尽管有很好的技术进步和临床经验,培养角化细胞移植仍然有实际的局限性。应用透明质酸酯膜作为角化细胞转移的载体底物,可以改善移植物处理:减少组织培养所需的总时间,进一步增强角化细胞的活力,因为可能在半流下移植。
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引用次数: 0
[Quality assurance in trauma surgery--meaning, characteristics and methods]. 【创伤外科质量保证——意义、特点与方法】。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
A Ekkernkamp

For trauma surgeons the compliance with and keeping to well organized and planned courses of action is obligatory. This is valid as well for the highly sensitive areas of preclinical emergency treatment, the primary treatment in the hospital and the exceptional management in polytrauma, as for treatment of solitary injuries of the musculo-skeletal system. Despite considerable activities--so far voluntarily--(optimization of courses of action, classification systems for injury grades, algorithms and close-meshed further education) control mechanisms are demanded by politicians and insurance companies. Therefore, comprehensive quality control is strived for in all different types of insurance coverage systems. In spite of justifiable restraints against control mechanisms, which oppose increasingly medical freedom in diagnostics and treatment, only cooperation with and proficient guidance of the often self-appointed quality assurance personnel is useful.

对于创伤外科医生来说,遵守和保持良好的组织和计划的行动方案是必须的。这也适用于临床前紧急治疗、医院初级治疗和多发创伤的特殊管理等高度敏感领域,以及肌肉骨骼系统孤立损伤的治疗。尽管有相当多的活动——到目前为止是自愿的——(优化行动方案、伤害等级分类系统、算法和紧密结合的继续教育),但政客和保险公司仍要求控制机制。因此,在各种不同类型的保险制度中,都力求全面的质量控制。尽管对控制机制有正当的限制,这些机制反对在诊断和治疗方面日益增加的医疗自由,但只有与往往自封的质量保证人员合作并得到他们的熟练指导才是有用的。
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引用次数: 0
[Committee "Hospital Hygiene and Infection Prevention" of the Robert-Koch institutes not authorized by a vote of the scientific organization]. [罗伯特-科赫研究所的“医院卫生和感染预防”委员会未经科学组织投票授权]。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
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引用次数: 0
[Radiation burden to the hands of surgeons in intramedullary nailing]. [髓内钉手术对外科医生手部的辐射负担]。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
L P Müller, J Suffner, K Wenda, W Mohr, L Rudig

During 41 procedures of intramedullary nailing of femoral and tibial fractures the primary surgeon and the first assistant wore ring dosimeters on their dominant index fingers. While the average fluoroscopy time per procedure was 4.6 min the average dose of radiation to the dominant hand of the primary surgeon was 1.27 mSv and 1.19 mSv to the first assistant. The dose limit for the extremities is 500 mSv per year recommended by the International Commission on Radiological Protection. Extrapolation of the average dose of the primary surgeon and first assistant per procedure of 1.23 mSv leads to the result, that the recommended dose limit of 500 mSv would only be exceeded if more than 407 intramedullary nailing procedures are carried out per year. The duration of fluoroscopy-time correlated with the radiation dose of the hands of the surgeons, though it was determined by phantom measurements that the majority of radiation exposure occurred during brief exposures of the hands in the direct X-ray beam on the X-ray tube near side of the patient.

在41例股骨胫骨骨折髓内钉治疗中,主刀医师和第一助理医师均在主指上佩戴环形剂量计。虽然每次手术的平均透视时间为4.6分钟,但主治医生主手的平均辐射剂量为1.27毫西弗,第一助理的平均辐射剂量为1.19毫西弗。国际放射防护委员会建议的四肢剂量上限为每年500毫西弗。根据初级外科医生和第一助理每次手术的平均剂量为1.23毫西弗的推断,只有在每年进行超过407次髓内钉手术的情况下,才会超过500毫西弗的建议剂量限值。透视时间的持续时间与外科医生的手的辐射剂量相关,尽管通过幻象测量确定,大多数辐射暴露发生在患者近侧x射线管直接x射线束的手部短暂暴露期间。
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引用次数: 0
[Revision surgery of knee endoprosthesis]. 膝关节内假体翻修手术。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-12-01
A Lahm, A Reichelt

Thirty-one revisions for aseptic or septic loosening of knee arthroplasty have been performed between 1983 and 1995. In 18 cases we had loosening of uni- or bicondylar prosthesis and in 13 cases a tricompartmental revision arthroplasty. With an average of 53 months (1.5 to 13 years) after the last operation 21 patients could be examined. Main reasons for failure of uni- and bicondylar prosthesis were as well a proceeding of the arthritis in other compartments, instability, incorrect alignment and other reasons depending on the surgical technique. We found similar reasons in aseptic loosening of total knee arthroplasties including wrong choice of non-constrained condylar prosthesis. Seven cases of late infection affected semi-constrained prosthesis. Two of the reimplantations in a 2-stage procedure failed. Using the Insall-Score in the follow-up the patients reached 71.9 points in the knee score and 58.9 points in the functional score. Patients with former aseptic loosening reached better results than these with septic loosening. 38% were absolutely painfree, 14% complained about permanent pain. Unlimited walking was found 5 times, none of the examined persons was unable to walk. Main problems in revision surgery concern reconstruction of a good alignment and the management of bone loss.

在1983年至1995年间,31例膝关节置换术的无菌或化脓性松动进行了翻修。其中18例为单髁或双髁假体松动,13例为三腔室关节翻修成形术。最后一次手术后平均53个月(1.5 ~ 13年)可检查21例患者。单髁假体和双髁假体失败的主要原因是其他隔室关节炎的进展、不稳定、不正确的对准和其他原因,这取决于手术技术。我们在全膝关节置换术中发现了类似的原因,包括错误选择无约束髁假体。晚期感染影响半约束假体7例。在两个阶段的手术中,有两个移植失败了。使用Insall-Score进行随访,患者膝关节评分达到71.9分,功能评分达到58.9分。无菌性松动患者比脓毒性松动患者效果更好。38%的人完全无痛,14%的人抱怨永久性疼痛。无节制行走5次,被检查者均无行走障碍。翻修手术的主要问题是重建良好的骨线和处理骨质流失。
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引用次数: 0
[Slit drainage in hip endoprosthesis--also an alternative in trauma surgery? A prospective follow-up study]. [切口引流在髋关节内假体中——也是创伤手术的一种选择?一项前瞻性随访研究]。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-10-01 DOI: 10.1007/BF02641224
F Graupe, M Eyssel, W Stock

Forty-four patients undergoing elective hip joint operation were analyzed to assess whether a new slit-suction drainage is less painful than the regular Redon-suction drainage. Main endpoint of the study was the effectiveness to draw off secretion and the pain at the time of removal of the drainage. Other endpoint was the rate of postoperative complications. At the time of removal patients with slit drain rarely complained about pain (p < 0.01). On contrary, patients with Redon drain always complained about pain. Clotting were seldom shown in slit drains and were frequently shown in Redon drains. Both slit drains and Redon drains were effective to drain secretion. As the new slit drain was more comfortable for patients following hip joint repair slit drain should always be used as suction drainage.

对44例接受择期髋关节手术的患者进行分析,以评估新的切口吸引引流是否比常规的redon -吸引引流更少痛苦。研究的主要终点是引流的有效性和引流时的疼痛。另一个终点是术后并发症的发生率。在拔除时,狭缝引流患者很少抱怨疼痛(p < 0.01)。相反,Redon引流的患者总是抱怨疼痛。在狭缝引流管中很少出现凝血,而在雷东引流管中经常出现凝血。狭缝引流和Redon引流均能有效引流分泌物。由于新型狭缝引流对髋关节修复术后患者更加舒适,因此应始终采用狭缝引流作为吸引引流。
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引用次数: 4
[Socioeconomic principles of medical care]. [医疗保健的社会经济原则]。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-10-01 DOI: 10.1007/BF02641225
H Kuderna
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引用次数: 1
[Projections and fiber characteristics of sensory afferents of the anterior cruciate ligament in an animal experiment]. 动物实验中前交叉韧带感觉传入神经的投射和纤维特征。
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-10-01 DOI: 10.1007/BF02641220
D Parsch, B Fromm, W Kummer

The sensory innervation of the rabbit anterior cruciate ligament was studied by retrograde tracing technique using wheat-germ-agglutinin-horseradish-peroxidase (WGA-HRP) and Fast Blue as neuronal tracers. Injection of the tracer into the ligament was followed by histo- and immunohistochemical investigation of labelled nerve cell bodies located in the dorsal root ganglia. In 4 animals we injected the tracer into the joint cavity to label general joint afferents. The segmental distribution of retrogradely labelled neurons following injection into the anterior cruciate ligament (L6, L7, S1) is significantly different from the distribution pattern after injection into the knee joint (L4-S2). Retrogradely labelled nerve cells innervating the anterior cruciate ligament were further investigated using immunohistochemical and morphometric analysis. The sensory innervation of the anterior cruciate ligament is therefore comprised of at least 2 different qualities of sensory afferent nerves: 1. Small neurones immunoreactive to the inflammatory peptide substance P most likely transmitting nociceptive information centrally (44%). 2. Large, presumably fast conducting A-fibre-afferents characterized by neurofilament proteins transmitting proprioceptive information from corpuscular mechanoreceptors (43%). The results of this study put further weight to the importance of the sensory role of the anterior cruciate ligament using neuroanatomical and immunohistochemical techniques.

采用逆行示踪技术,以小麦-细菌-凝集素-辣根-过氧化物酶(WGA-HRP)和Fast Blue为神经元示踪剂,研究了兔前交叉韧带的感觉神经支配。将示踪剂注射到韧带中,然后对位于背根神经节的标记神经细胞体进行组织和免疫组织化学研究。在4只动物中,我们将示踪剂注射到关节腔中以标记一般关节传入事件。前交叉韧带(L6, L7, S1)注射后逆行标记神经元的节段性分布与膝关节(L4-S2)注射后的分布模式有显著差异。逆行标记的神经细胞支配前交叉韧带进一步研究免疫组织化学和形态计量学分析。因此,前交叉韧带的感觉神经支配由至少2种不同的感觉传入神经组成:1。对炎性肽P物质有免疫反应的小神经元最有可能集中传递伤害性信息(44%)。2. 大的,可能是快速传导的a纤维传入,以神经丝蛋白从微粒机械感受器传递本体感觉信息为特征(43%)。本研究结果利用神经解剖学和免疫组织化学技术进一步强调了前交叉韧带感觉作用的重要性。
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引用次数: 2
[Does the degree of dislocation correlate with therapy procedure in supracondylar humerus fractures in childhood?]. 儿童肱骨髁上骨折的脱位程度是否与治疗方法相关?
IF 0.8 4区 医学 Q4 EMERGENCY MEDICINE Pub Date : 1996-10-01 DOI: 10.1007/BF02641221
H P Hohl, L Wessel, K L Waag

Hundred and twenty-eight supracondylar fractures of the humerus were studied retrospectively after an follow-up time of 4.3 years (1 to 17.8 years). In 87 cases (68%) the operative procedure was the closed reduction and percutaneous crossed-pin fixation for 19 fractures type III (56%). 22 fractures type II (76%) and 46 fractures type I (85%), whereas 41 fractures were treated by open reduction and crossed-pin fixation. The findings were evaluated according to "Flynn's criteria" leading to the following results: "excellent" 77 times (60.2%), "good" 44 times (34.4%) "fair" 3 times (2.3%) and "poor" 4 times (3.1%). Our results show that with approximately 50% of all fractures type III the treatment by closed reduction and percutaneous crossed-pin fixation leads to a very good long-term result. On the other hand, rotated or interponated fractures type I and II require an open reduction and crossed-pin fixation. Independent of the type of fracture, the closed reduction and percutaneous crossed-pin fixation should always be taken into consideration. Exceptions are open fractures and those with multiple fragments.

回顾性研究了128例肱骨髁上骨折,随访时间为4.3年(1 ~ 17.8年)。87例(68%)III型骨折采用闭合复位经皮交叉针固定19例(56%)。II型骨折22例(76%),I型骨折46例(85%),而开放复位交叉针固定41例。根据“弗林标准”的评价结果,“优秀”77次(60.2%),“良好”44次(34.4%)。“一般”3次(2.3%),“差”4次(3.1%)。我们的研究结果表明,对于大约50%的III型骨折,采用闭合复位和经皮交叉针固定治疗可获得非常好的长期效果。另一方面,I型和II型旋转或交叉骨折需要切开复位和交叉针固定。与骨折类型无关,应始终考虑闭合复位和经皮交叉针固定。开放性骨折和多发骨折是例外。
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引用次数: 1
期刊
Unfallchirurgie
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