Pub Date : 2024-06-01Epub Date: 2023-10-18DOI: 10.23736/S2724-5691.23.10039-6
Yandong Zhang, Xiongwei Yan
{"title":"Comparison of clinical effects of screw fixation and plate fixation for Haraguchi type I posterior malleolus fractures.","authors":"Yandong Zhang, Xiongwei Yan","doi":"10.23736/S2724-5691.23.10039-6","DOIUrl":"10.23736/S2724-5691.23.10039-6","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"41239224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-12-13DOI: 10.23736/S2724-5691.23.10162-6
Liping Wang, Weizhen Wang
{"title":"Symptom management and nursing interventions for postoperative bladder instillation chemotherapy in bladder cancer patients.","authors":"Liping Wang, Weizhen Wang","doi":"10.23736/S2724-5691.23.10162-6","DOIUrl":"10.23736/S2724-5691.23.10162-6","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810425","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-02-22DOI: 10.23736/S2724-5691.23.10230-9
Serena Mantova, Fabrizio Rebecchi, Mostafa R Elkeleny, Elettra Ugliono, Ahmed M Mansour, Mario Morino
Background: Large hiatal hernias (LHH) account for 5-10% of all hiatal hernias. Surgery of LHH should be associated with low rates of postoperative complications and recurrences, to guarantee a favorable quality of life (QoL). Data on long-term results of laparoscopic repair of LHH are lacking. The objective of our study is to evaluate the long-term clinical outcomes of laparoscopic LHH management in a high-volume experienced center.
Methods: Patients who had undergone elective laparoscopic repair of LHH between January 1992 and December 2008 at the Center of Minimally Invasive Surgery of the Department of Surgical Sciences, University of Turin, Italy were included. Preoperative and intraoperative data were collected from patients' charts. Patients were clinically evaluated at long-term postoperative follow-up to assess control of symptoms, degree of satisfaction with surgery, and QoL.
Results: At mean follow-up of 240 months (range 168-348), 81 patients were available for clinical evaluation. Severe heartburn was reported by six patients (7.4%), while severe post-prandial epigastric pain by three (3.7%). Recurrent coughing episodes were described by six patients (7.4%), while occasional mild episodes of transient dysphagia by 13 (16%). No gas bloat detected. Proton Pump Inhibitors were taken by 22 patients (27.2%) to control symptoms. The Modified Italian Gastroesophageal Reflux Disease-Health Related Quality of Life (MI-GERD-HRQL) score decreased significantly from 40 to 7 (P<0.0001) postoperatively. Satisfaction was achieved in 76 patients (93.8%) with an average satisfaction index of 8.6 (IQR 8-10).
Conclusions: Laparoscopic LHH repair is effective when performed in a specialized center, with long-lasting significant improvements of symptoms and QoL.
{"title":"Long-term clinical evaluation of laparoscopic management of large hiatal hernias.","authors":"Serena Mantova, Fabrizio Rebecchi, Mostafa R Elkeleny, Elettra Ugliono, Ahmed M Mansour, Mario Morino","doi":"10.23736/S2724-5691.23.10230-9","DOIUrl":"10.23736/S2724-5691.23.10230-9","url":null,"abstract":"<p><strong>Background: </strong>Large hiatal hernias (LHH) account for 5-10% of all hiatal hernias. Surgery of LHH should be associated with low rates of postoperative complications and recurrences, to guarantee a favorable quality of life (QoL). Data on long-term results of laparoscopic repair of LHH are lacking. The objective of our study is to evaluate the long-term clinical outcomes of laparoscopic LHH management in a high-volume experienced center.</p><p><strong>Methods: </strong>Patients who had undergone elective laparoscopic repair of LHH between January 1992 and December 2008 at the Center of Minimally Invasive Surgery of the Department of Surgical Sciences, University of Turin, Italy were included. Preoperative and intraoperative data were collected from patients' charts. Patients were clinically evaluated at long-term postoperative follow-up to assess control of symptoms, degree of satisfaction with surgery, and QoL.</p><p><strong>Results: </strong>At mean follow-up of 240 months (range 168-348), 81 patients were available for clinical evaluation. Severe heartburn was reported by six patients (7.4%), while severe post-prandial epigastric pain by three (3.7%). Recurrent coughing episodes were described by six patients (7.4%), while occasional mild episodes of transient dysphagia by 13 (16%). No gas bloat detected. Proton Pump Inhibitors were taken by 22 patients (27.2%) to control symptoms. The Modified Italian Gastroesophageal Reflux Disease-Health Related Quality of Life (MI-GERD-HRQL) score decreased significantly from 40 to 7 (P<0.0001) postoperatively. Satisfaction was achieved in 76 patients (93.8%) with an average satisfaction index of 8.6 (IQR 8-10).</p><p><strong>Conclusions: </strong>Laparoscopic LHH repair is effective when performed in a specialized center, with long-lasting significant improvements of symptoms and QoL.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.4,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139933198","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-03-29DOI: 10.23736/S2724-5691.24.10228-6
Simona Ascanelli, Eleonora Rossin, Filippo Aisoni, Elisabetta Sette, Laura Chimisso, Giorgia Valpiani, Anna Costanzini, Roberto DE Giorgio, Carlo V Feo
Background: Botulinum toxin is an effective therapeutic option for chronic anal fissure. However, there is no evidence about treatment standardization and long-term follow-up. We aimed to evaluate the short- and long-term efficacy and safety of botulinum toxin compared to close lateral internal sphincterotomy, with a 5-year follow-up.
Methods: This was a prospective, controlled, single-center study conducted at University Hospital of Ferrara, Ferrara, Italy. The primary outcome was fissure healing at 1 month. Secondary outcomes were Quality-of-Life (QoL) at 1 month and after 5 years, and fissure recurrence at 6 months and 5 years.
Results: A total of 59 patients received botulinum toxin injection (Botox), and 32 underwent lateral internal sphincterotomy. At 1 month after treatments, postoperative pain decreased faster and significantly more in the Botox group (30 vs. 60 mm; P<0.001); fissure re-epithelization was observed in 59.4% of the surgical group compared to 25.4% of Botox (P=0.0001). Anal sphincter pressures decreased more in surgical group (P=0.044), although severe anal incontinence was present only in this subset (6.2%; P=0.041). Compared to surgery, patients who received Botox had higher satisfaction rates (P<0.001). Fissure recurrence at 6 months was more common in Botox than surgical group (16.9% vs. 3.2%, respectively; P=0.053). The overall healing rate improved in all patients and persisted at 12 months and 5 years in both groups with overall high patient satisfaction despite mild anal incontinence in 21.8% in the surgery group (P<0.05).
Conclusions: Botox, rather than surgery, should be considered the first-line treatment for chronic anal fissure.
{"title":"Botulinum toxin injection for chronic anal fissure: a prospective controlled study with long follow-up.","authors":"Simona Ascanelli, Eleonora Rossin, Filippo Aisoni, Elisabetta Sette, Laura Chimisso, Giorgia Valpiani, Anna Costanzini, Roberto DE Giorgio, Carlo V Feo","doi":"10.23736/S2724-5691.24.10228-6","DOIUrl":"10.23736/S2724-5691.24.10228-6","url":null,"abstract":"<p><strong>Background: </strong>Botulinum toxin is an effective therapeutic option for chronic anal fissure. However, there is no evidence about treatment standardization and long-term follow-up. We aimed to evaluate the short- and long-term efficacy and safety of botulinum toxin compared to close lateral internal sphincterotomy, with a 5-year follow-up.</p><p><strong>Methods: </strong>This was a prospective, controlled, single-center study conducted at University Hospital of Ferrara, Ferrara, Italy. The primary outcome was fissure healing at 1 month. Secondary outcomes were Quality-of-Life (QoL) at 1 month and after 5 years, and fissure recurrence at 6 months and 5 years.</p><p><strong>Results: </strong>A total of 59 patients received botulinum toxin injection (Botox), and 32 underwent lateral internal sphincterotomy. At 1 month after treatments, postoperative pain decreased faster and significantly more in the Botox group (30 vs. 60 mm; P<0.001); fissure re-epithelization was observed in 59.4% of the surgical group compared to 25.4% of Botox (P=0.0001). Anal sphincter pressures decreased more in surgical group (P=0.044), although severe anal incontinence was present only in this subset (6.2%; P=0.041). Compared to surgery, patients who received Botox had higher satisfaction rates (P<0.001). Fissure recurrence at 6 months was more common in Botox than surgical group (16.9% vs. 3.2%, respectively; P=0.053). The overall healing rate improved in all patients and persisted at 12 months and 5 years in both groups with overall high patient satisfaction despite mild anal incontinence in 21.8% in the surgery group (P<0.05).</p><p><strong>Conclusions: </strong>Botox, rather than surgery, should be considered the first-line treatment for chronic anal fissure.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319451","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01DOI: 10.23736/S2724-5691.23.10165-1
Belinda DE Simone, Fikri M Abu-Zidan, Mauro Podda, Gianluca Pellino, Massimo Sartelli, Federico Coccolini, Salomone DI Saverio, Walter L Biffl, Haytham M Kaafarani, Ernest E Moore, Jugdeep K Dhesi, Susan Moug, Luca Ansaloni, Nicola Avenia, Fausto Catena
Background: Colorectal (CRC) cancer is becoming a disease of the elderly. Ageing is the most significant risk factor for presenting CRC. Early diagnosis of CRC and management is the best way in achieving good outcomes and longer survival but patients aged ≥75 years are usually not screened for CRC. This group of patients is often required to be managed when they are symptomatic in the emergency setting with high morbidity and mortality rates. Our main aim is to provide clinical data about the management of elderly patients presenting complicated colorectal cancer who required emergency surgical management to improve their care.
Methods: The management of complicated COlorectal cancer in OLDER patients (CO-OLDER; ClinicalTrials.gov ID: NCT05788224; evaluated by the local ethical committee CPP EST III-France with the national number 2023-A01094-41) in the emergency setting project provides carrying out an observational multicenter international cohort study aimed to collect data about patients aged ≥75 years to assess modifiable risk factors for negative outcomes and mortality correlated to the emergency surgical management of this group of patients at risk admitted with a complicated (obstructed and perforated) CRC. The CO-OLDER protocol was approved by Institutional Review Board and released. Each CO-OLDER collaborator is asked to enroll ≥25 patients over a study period from 1st January 2018 to 30th October 2023. Data will be analyzed comparing two periods of study: before and after the COVID-19 pandemic. A sample size of 240 prospectively enrolled patients with obstructed colorectal cancer in a 5-month period was calculated. The secured database for entering anonymized data will be available for the period necessary to achieve the highest possible participation.
Results: One hundred eighty hospitals asked to be a CO-OLDER collaborator, with 36 potentially involved countries over the world.
Conclusions: The CO-OLDER project aims to improve the management of elderly people presenting with a complicated colorectal cancer in the emergency setting. Our observational global study can provide valuable data on the effectiveness of different management strategies in improving primary assessment, management and outcomes for elderly patients with obstructed or perforated colorectal cancer in the emergency setting, guiding clinical decision-making. This information can help healthcare providers make informed decisions about the best course of action for these patients.
{"title":"The management of complicated colorectal cancer in older patients in a global perspective after COVID-19: the CO-OLDER WSES project.","authors":"Belinda DE Simone, Fikri M Abu-Zidan, Mauro Podda, Gianluca Pellino, Massimo Sartelli, Federico Coccolini, Salomone DI Saverio, Walter L Biffl, Haytham M Kaafarani, Ernest E Moore, Jugdeep K Dhesi, Susan Moug, Luca Ansaloni, Nicola Avenia, Fausto Catena","doi":"10.23736/S2724-5691.23.10165-1","DOIUrl":"10.23736/S2724-5691.23.10165-1","url":null,"abstract":"<p><strong>Background: </strong>Colorectal (CRC) cancer is becoming a disease of the elderly. Ageing is the most significant risk factor for presenting CRC. Early diagnosis of CRC and management is the best way in achieving good outcomes and longer survival but patients aged ≥75 years are usually not screened for CRC. This group of patients is often required to be managed when they are symptomatic in the emergency setting with high morbidity and mortality rates. Our main aim is to provide clinical data about the management of elderly patients presenting complicated colorectal cancer who required emergency surgical management to improve their care.</p><p><strong>Methods: </strong>The management of complicated COlorectal cancer in OLDER patients (CO-OLDER; ClinicalTrials.gov ID: NCT05788224; evaluated by the local ethical committee CPP EST III-France with the national number 2023-A01094-41) in the emergency setting project provides carrying out an observational multicenter international cohort study aimed to collect data about patients aged ≥75 years to assess modifiable risk factors for negative outcomes and mortality correlated to the emergency surgical management of this group of patients at risk admitted with a complicated (obstructed and perforated) CRC. The CO-OLDER protocol was approved by Institutional Review Board and released. Each CO-OLDER collaborator is asked to enroll ≥25 patients over a study period from 1st January 2018 to 30th October 2023. Data will be analyzed comparing two periods of study: before and after the COVID-19 pandemic. A sample size of 240 prospectively enrolled patients with obstructed colorectal cancer in a 5-month period was calculated. The secured database for entering anonymized data will be available for the period necessary to achieve the highest possible participation.</p><p><strong>Results: </strong>One hundred eighty hospitals asked to be a CO-OLDER collaborator, with 36 potentially involved countries over the world.</p><p><strong>Conclusions: </strong>The CO-OLDER project aims to improve the management of elderly people presenting with a complicated colorectal cancer in the emergency setting. Our observational global study can provide valuable data on the effectiveness of different management strategies in improving primary assessment, management and outcomes for elderly patients with obstructed or perforated colorectal cancer in the emergency setting, guiding clinical decision-making. This information can help healthcare providers make informed decisions about the best course of action for these patients.</p>","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"141284887","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-01-24DOI: 10.23736/S2724-5691.23.10201-2
Yaoyao Dai, Ye Wei, Jian Fu, Yingying Han, Juan Yang, Jiamin Mao, Rongrong Lu
{"title":"The current application and research progress of vitamin D in improving the efficacy of tuberculosis treatment.","authors":"Yaoyao Dai, Ye Wei, Jian Fu, Yingying Han, Juan Yang, Jiamin Mao, Rongrong Lu","doi":"10.23736/S2724-5691.23.10201-2","DOIUrl":"10.23736/S2724-5691.23.10201-2","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139543183","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2024-03-29DOI: 10.23736/S2724-5691.24.10293-6
Damiano Bisogni, Luca Talamucci, Michele Rossi, Fabio Staderini, Salvatore DE Masi, Laura Fortuna, Fabio Cianchi
{"title":"Lights and shadows of three endoscopic techniques as organ-sparing alternatives to surgery for anastomotic leaks after esophago-gastric surgery: results and data analysis of an Italian referral single center for gastrointestinal disease treatment.","authors":"Damiano Bisogni, Luca Talamucci, Michele Rossi, Fabio Staderini, Salvatore DE Masi, Laura Fortuna, Fabio Cianchi","doi":"10.23736/S2724-5691.24.10293-6","DOIUrl":"10.23736/S2724-5691.24.10293-6","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"140319452","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-12-13DOI: 10.23736/S2724-5691.23.10160-2
Yanhong Zhao, Hui Zhu
{"title":"Observation of the effectiveness of problem-based learning in orthopedic nursing clinical preceptorship.","authors":"Yanhong Zhao, Hui Zhu","doi":"10.23736/S2724-5691.23.10160-2","DOIUrl":"10.23736/S2724-5691.23.10160-2","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138810499","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2024-06-01Epub Date: 2023-12-21DOI: 10.23736/S2724-5691.23.10170-5
Xiao Luo, Ling Chen, Juxiang Li, Jingsong Xu, Ran Liao
{"title":"Application of Naoxintong combined with warfarin in anticoagulant therapy in elderly patients with coronary heart disease and atrial fibrillation.","authors":"Xiao Luo, Ling Chen, Juxiang Li, Jingsong Xu, Ran Liao","doi":"10.23736/S2724-5691.23.10170-5","DOIUrl":"10.23736/S2724-5691.23.10170-5","url":null,"abstract":"","PeriodicalId":29847,"journal":{"name":"Minerva Surgery","volume":null,"pages":null},"PeriodicalIF":1.8,"publicationDate":"2024-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"138831946","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}