Background: Cerebral Palsy (CP) is a physical disability impacting movement, posture, and communication. For children with CP and severe communication challenges, methods like Partner Assisted Scanning (PAS) are invaluable. Despite its effectiveness, research on PAS in the context of Thailand is scarce. Objectives: This study aimed to develop and validate a communication book and related materials for children with CP, utilizing the PAS method. Additionally, the study aimed to analyze communication partners’ satisfaction levels with the communication book. Materials and methods: The study involved two phases. First, four instruments were developed and assessed for content validity: The communication Abilities Assessment, the Communication Partners’ Satisfaction Survey, the Communication Book Manual, and the Communication Book. In the second phase, these instruments were tested with three families, evaluating partner satisfaction and addressing encountered issues. Results: The study demonstrated high content validity of the communication book (overall validity index=0.97) as assessed by specialists. Feedback highlighted concerns about the book’s format and the time needed for children to grasp its usage. However, communication partners expressed overall high satisfaction (mean=4.67, SD=0.49). Conclusion: This pilot study establishes the robust content validity of the communication book developed using the PAS method. Moreover, it underscores high satisfaction levels among communication partners, affirming the potential of the communication book to enhance communication skills in children with CP.
背景：脑瘫（CP）是一种影响运动、姿势和交流的肢体残疾。对于患有脑瘫和严重交流障碍的儿童来说，伙伴辅助扫描（PAS）等方法非常重要。尽管这种方法很有效，但在泰国，有关伴侣辅助扫描的研究却很少。研究目的本研究旨在利用伴侣辅助扫描法，为患有先天性脑瘫的儿童编写并验证一本沟通手册和相关材料。此外，本研究还旨在分析交流伙伴对交流手册的满意度。材料和方法：研究分为两个阶段。首先，开发了四种工具，并对其内容有效性进行了评估：沟通能力评估》、《沟通伙伴满意度调查》、《沟通手册》和《沟通手册》。在第二阶段，这些工具在三个家庭中进行了测试，评估了伙伴的满意度并解决了遇到的问题。结果：经专家评估，研究表明沟通手册的内容有效性较高（总体有效性指数=0.97）。反馈意见强调了对该书格式和儿童掌握其用法所需时间的担忧。不过，交流伙伴对该书的总体满意度很高（平均值=4.67，标准差=0.49）。结论这项试点研究证实了使用 PAS 方法编写的沟通手册在内容上的有效性。此外，它还强调了沟通伙伴的高满意度，肯定了沟通手册在提高脊髓灰质炎儿童沟通技能方面的潜力。
{"title":"Development of a communication book for children with cerebral palsy and communication disorders using the partner assisted scanning method: A pilot study","authors":"Worakanok Pappring, Supaporn Chinchai","doi":"10.12982/jams.2024.003","DOIUrl":"https://doi.org/10.12982/jams.2024.003","url":null,"abstract":"Background: Cerebral Palsy (CP) is a physical disability impacting movement, posture, and communication. For children with CP and severe communication challenges, methods like Partner Assisted Scanning (PAS) are invaluable. Despite its effectiveness, research on PAS in the context of Thailand is scarce. Objectives: This study aimed to develop and validate a communication book and related materials for children with CP, utilizing the PAS method. Additionally, the study aimed to analyze communication partners’ satisfaction levels with the communication book. Materials and methods: The study involved two phases. First, four instruments were developed and assessed for content validity: The communication Abilities Assessment, the Communication Partners’ Satisfaction Survey, the Communication Book Manual, and the Communication Book. In the second phase, these instruments were tested with three families, evaluating partner satisfaction and addressing encountered issues. Results: The study demonstrated high content validity of the communication book (overall validity index=0.97) as assessed by specialists. Feedback highlighted concerns about the book’s format and the time needed for children to grasp its usage. However, communication partners expressed overall high satisfaction (mean=4.67, SD=0.49). Conclusion: This pilot study establishes the robust content validity of the communication book developed using the PAS method. Moreover, it underscores high satisfaction levels among communication partners, affirming the potential of the communication book to enhance communication skills in children with CP.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"50 11","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139123838","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Patcharanun Sutthiphan, Phuanjai Rattakorn, Supaporn Chinchai, N. Wongpakaran, S. Tanprawate, Nopdanai Sirimaharaj
Background: Older adults with mild neurocognitive disorders (mild NCD) have a higher risk of major NCD. Cognitive deterioration can cause a deficit in working memory and language. Recent studies have shown some involvement overlapping the brain structure of working memory and language skills. Therefore, working memory intervention effectively enhances language skills in mild NCD. However, more research on this topic in Thailand is required. Objectives: This study aimed to develop and implement a pilot study on a working memory program for improving language skills in older adults with mild NCD. Materials and methods: This study was a developmental research design with two phases. Phase one involved the development and examination of the content validity of the working memory program for improving language skills by five experts. Phase two involved piloting the program with three older adults with mild NCD. The participants were asked to provide suggestions about the clarity of content and images, language usage, font size, the comprehensibility of instructions in each activity, and the quality of audio files used to complement the program activities through semi-structured interviews. Descriptive statistics were employed to analyze the collected data. Results: The program comprised nine activities associated with the phonological loop, visual-spatial sketchpad, episodic buffer, and central executive tasks. The program’s content validity was evaluated by five experts, resulting in a content validity index of 0.94, meeting the established criteria. Among the pilot users, three participants meeting the specified criteria indicated their ability to use and practice the program at home effectively. While most participants agreed that the images were clear and the font size was appropriate, there were concerns regarding the clarity of the training process steps and instructions. Additionally, some participants encountered challenges in accessing audio files through quick response (QR) codes. Conclusion: In summary, the pilot study of the working memory program for improving language skills in older adults with mild NCD passed the content validity test and underwent revisions based on suggestions from the pilot users. Consequently, the program could enhance the language abilities of older adults with mild NCD. The next phase will investigate its effectiveness in improving language skills in older adults with mild NCD.
{"title":"Working memory program for improving language skills in older adults with mild neurocognitive disorders: A pilot study","authors":"Patcharanun Sutthiphan, Phuanjai Rattakorn, Supaporn Chinchai, N. Wongpakaran, S. Tanprawate, Nopdanai Sirimaharaj","doi":"10.12982/jams.2024.013","DOIUrl":"https://doi.org/10.12982/jams.2024.013","url":null,"abstract":"Background: Older adults with mild neurocognitive disorders (mild NCD) have a higher risk of major NCD. Cognitive deterioration can cause a deficit in working memory and language. Recent studies have shown some involvement overlapping the brain structure of working memory and language skills. Therefore, working memory intervention effectively enhances language skills in mild NCD. However, more research on this topic in Thailand is required. Objectives: This study aimed to develop and implement a pilot study on a working memory program for improving language skills in older adults with mild NCD. Materials and methods: This study was a developmental research design with two phases. Phase one involved the development and examination of the content validity of the working memory program for improving language skills by five experts. Phase two involved piloting the program with three older adults with mild NCD. The participants were asked to provide suggestions about the clarity of content and images, language usage, font size, the comprehensibility of instructions in each activity, and the quality of audio files used to complement the program activities through semi-structured interviews. Descriptive statistics were employed to analyze the collected data. Results: The program comprised nine activities associated with the phonological loop, visual-spatial sketchpad, episodic buffer, and central executive tasks. The program’s content validity was evaluated by five experts, resulting in a content validity index of 0.94, meeting the established criteria. Among the pilot users, three participants meeting the specified criteria indicated their ability to use and practice the program at home effectively. While most participants agreed that the images were clear and the font size was appropriate, there were concerns regarding the clarity of the training process steps and instructions. Additionally, some participants encountered challenges in accessing audio files through quick response (QR) codes. Conclusion: In summary, the pilot study of the working memory program for improving language skills in older adults with mild NCD passed the content validity test and underwent revisions based on suggestions from the pilot users. Consequently, the program could enhance the language abilities of older adults with mild NCD. The next phase will investigate its effectiveness in improving language skills in older adults with mild NCD.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"53 2","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120132","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Background: Cleft palate is a congenital disability affecting the palate’s structure and function, which may lead to delayed speech and language development and communication disorders. There is a shortage of speech therapists in Thailand. Therefore, developing a manual for speech and language treatment for the parents of children with a cleft palate would be an essential early intervention that parents could perform. Objectives: This research aimed to develop a speech and language treatment manual for parents of children with cleft palate ages 0-3 years old and evaluate the manual’s effectiveness, satisfaction, and feedback. Materials and methods: This research was divided into Phase 1, which involved developing a speech and language treatment manual for parents of children with cleft palate ages 0-3 years old and assessing its validity and reliability. Phase 2 tested the manual’s effectiveness by conducting a three-month of 16 participants, who were divided into two groups: A control group without the manual and an experimental group with the manual and phase 3 data analysis. Results: The content validity of the manual and satisfaction of the questionnaires were found to have a content validity index of 0.87 and 0.92, respectively. The total language and speech development scores before and after participating between groups found a statistically significant difference. After participating, the number of the experimental group who passed the 90th percentile of language development was higher than the control group. The language between the children and parents showed that the experimental group displayed more communication skills than the control group. Conclusion: The speech and language treatment manual for parents of children with cleft palate ages 0-3 years old could stimulate the language and speech development of the experimental group more effectively than the control group that did not receive the manual.
{"title":"The Development of manual for speech and language treatment for parents of children with cleft palate ages 0-3 years old","authors":"Pechcharat Jaiyong, Phuanjai Rattakorn, Supaporn Chinchai","doi":"10.12982/jams.2024.007","DOIUrl":"https://doi.org/10.12982/jams.2024.007","url":null,"abstract":"Background: Cleft palate is a congenital disability affecting the palate’s structure and function, which may lead to delayed speech and language development and communication disorders. There is a shortage of speech therapists in Thailand. Therefore, developing a manual for speech and language treatment for the parents of children with a cleft palate would be an essential early intervention that parents could perform. Objectives: This research aimed to develop a speech and language treatment manual for parents of children with cleft palate ages 0-3 years old and evaluate the manual’s effectiveness, satisfaction, and feedback. Materials and methods: This research was divided into Phase 1, which involved developing a speech and language treatment manual for parents of children with cleft palate ages 0-3 years old and assessing its validity and reliability. Phase 2 tested the manual’s effectiveness by conducting a three-month of 16 participants, who were divided into two groups: A control group without the manual and an experimental group with the manual and phase 3 data analysis. Results: The content validity of the manual and satisfaction of the questionnaires were found to have a content validity index of 0.87 and 0.92, respectively. The total language and speech development scores before and after participating between groups found a statistically significant difference. After participating, the number of the experimental group who passed the 90th percentile of language development was higher than the control group. The language between the children and parents showed that the experimental group displayed more communication skills than the control group. Conclusion: The speech and language treatment manual for parents of children with cleft palate ages 0-3 years old could stimulate the language and speech development of the experimental group more effectively than the control group that did not receive the manual.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"50 3","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139123854","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Cressey, Sudalak Sankunkit, Chonnipa Chaovatin, Natteewan Doungjinda, A. Lungkaphin
Background: Although atorvastatin is commonly used as a hypolipidemic agent, it confers many health benefits in which the underlying mechanisms are not fully understood. We have previously shown that combined treatment of atorvastatin and insulin effectively restored renal function of streptozotocin (STZ)-induced diabetic rats; nevertheless, the underlying mechanism was not known. Objective: To determine whether the reno-protective effect of atorvastatin and insulin is mediated through its impact on autophagy. Materials and methods: Markers of autophagy, LC3, and p62/SQSTM1, in rat kidney tissues and cell lines treated with atorvastatin and/or insulin were determined by Western blot analysis. Results: Levels of both LC3-I and LC3-II proteins in kidney tissues of STZ-diabetic rats treated with atorvastatin and insulin were significantly increased. The autophagic flux was examined in vitro and showed that high glucose culture conditions suppressed the autophagic flux in kidney cells. Treatment with insulin moderately increased the conversion of LC3-I to LC3-II. Interestingly, atorvastatin increased autophagic flux only in the hyperglycemic but not in the normoglycemic condition. p62/SQSTM1 protein level was decreased in response to high glucose treatment but increased with the addition of insulin and/or atorvastatin. Conclusion: This study has demonstrated that atorvastatin may represent a novel regimen in providing prevention and protection for diabetic nephropathy through the underlying mechanisms of inducing autophagy and p62/SQSTM1.
{"title":"Atorvastatin increases autophagic flux and p62/SQSTM1 of kidney cells in hyperglycemic conditions and treatment in combination with insulin improves renal function of streptozotocin (STZ)-induced diabetic rats","authors":"R. Cressey, Sudalak Sankunkit, Chonnipa Chaovatin, Natteewan Doungjinda, A. Lungkaphin","doi":"10.12982/jams.2024.016","DOIUrl":"https://doi.org/10.12982/jams.2024.016","url":null,"abstract":"Background: Although atorvastatin is commonly used as a hypolipidemic agent, it confers many health benefits in which the underlying mechanisms are not fully understood. We have previously shown that combined treatment of atorvastatin and insulin effectively restored renal function of streptozotocin (STZ)-induced diabetic rats; nevertheless, the underlying mechanism was not known. Objective: To determine whether the reno-protective effect of atorvastatin and insulin is mediated through its impact on autophagy. Materials and methods: Markers of autophagy, LC3, and p62/SQSTM1, in rat kidney tissues and cell lines treated with atorvastatin and/or insulin were determined by Western blot analysis. Results: Levels of both LC3-I and LC3-II proteins in kidney tissues of STZ-diabetic rats treated with atorvastatin and insulin were significantly increased. The autophagic flux was examined in vitro and showed that high glucose culture conditions suppressed the autophagic flux in kidney cells. Treatment with insulin moderately increased the conversion of LC3-I to LC3-II. Interestingly, atorvastatin increased autophagic flux only in the hyperglycemic but not in the normoglycemic condition. p62/SQSTM1 protein level was decreased in response to high glucose treatment but increased with the addition of insulin and/or atorvastatin. Conclusion: This study has demonstrated that atorvastatin may represent a novel regimen in providing prevention and protection for diabetic nephropathy through the underlying mechanisms of inducing autophagy and p62/SQSTM1.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"54 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120468","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth
Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.
{"title":"Reliability of running parameters using fitness watches synced with accelerometers during outdoor runs","authors":"Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth","doi":"10.12982/jams.2024.019","DOIUrl":"https://doi.org/10.12982/jams.2024.019","url":null,"abstract":"Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"51 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120496","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jureemas Wilaklang, Kalyanee Makarabhirom, S. Thayansin, Phurich Praneetvatakul
Background: Unilateral vocal fold mobility impairment (UVFMI) causes dysphonia and/or dysphagia, which can significantly affect a patient’s ability to communicate and perform regular daily life activities as well as the quality of life. Voice therapy offers a less invasive and more preferential method for patients. However, there are limitations concerning the integration of multiple therapy approaches. Voice therapy exercises with clear methodologies are required to plan and conduct therapy systematically, and frequency would be required for each exercise. Therefore, this study was conducted by applying the protocols of voice therapy in adult patients with unilateral vocal fold mobility impairment. Objective: This feasibility study is a prospective cohort, pre-post single arm, designed to determine whether the voice therapy protocol (VTP) can enhance voice quality in adult patients with unilateral vocal fold mobility impairment (UVFMI) in a pilot study. Materials and methods: All subjects received 12 sessions of voice therapy protocol, with each session conducted weekly for 45 minutes. The voice therapy protocol applied in this study consisted of vocal hygiene education, abdominal breathing exercises, vocal function exercises, pushing exercises, muscle relaxation exercises, and applied resonance voice therapy. The outcomes of protocols for voice therapy were measured before and after treatment using subjective voice assessments (GIRBAS scale) and objective voice assessments (Dr. Speech program and electroglottography-EGG). Results: Cases 2, 7, 10, 11, and 13 improved after receiving VTP. As for other participants, there are still some voice parameters that need to be monitored. Overall, it was found that the participants’ voice parameters were changing within the acceptable range, with MPT, jitter, shimmer, and HNR values significantly different (p<0.05). Conclusion: The findings of this study indicated that the voice therapy protocol was a worthwhile alternative and could be used to develop further treatment guidelines for adult patients with UVFMI at a speech clinic.
{"title":"Efficacy of the voice therapy protocol (VTP) for adult patients with unilateral vocal fold mobility impairment; a feasibility study","authors":"Jureemas Wilaklang, Kalyanee Makarabhirom, S. Thayansin, Phurich Praneetvatakul","doi":"10.12982/jams.2024.017","DOIUrl":"https://doi.org/10.12982/jams.2024.017","url":null,"abstract":"Background: Unilateral vocal fold mobility impairment (UVFMI) causes dysphonia and/or dysphagia, which can significantly affect a patient’s ability to communicate and perform regular daily life activities as well as the quality of life. Voice therapy offers a less invasive and more preferential method for patients. However, there are limitations concerning the integration of multiple therapy approaches. Voice therapy exercises with clear methodologies are required to plan and conduct therapy systematically, and frequency would be required for each exercise. Therefore, this study was conducted by applying the protocols of voice therapy in adult patients with unilateral vocal fold mobility impairment. Objective: This feasibility study is a prospective cohort, pre-post single arm, designed to determine whether the voice therapy protocol (VTP) can enhance voice quality in adult patients with unilateral vocal fold mobility impairment (UVFMI) in a pilot study. Materials and methods: All subjects received 12 sessions of voice therapy protocol, with each session conducted weekly for 45 minutes. The voice therapy protocol applied in this study consisted of vocal hygiene education, abdominal breathing exercises, vocal function exercises, pushing exercises, muscle relaxation exercises, and applied resonance voice therapy. The outcomes of protocols for voice therapy were measured before and after treatment using subjective voice assessments (GIRBAS scale) and objective voice assessments (Dr. Speech program and electroglottography-EGG). Results: Cases 2, 7, 10, 11, and 13 improved after receiving VTP. As for other participants, there are still some voice parameters that need to be monitored. Overall, it was found that the participants’ voice parameters were changing within the acceptable range, with MPT, jitter, shimmer, and HNR values significantly different (p<0.05). Conclusion: The findings of this study indicated that the voice therapy protocol was a worthwhile alternative and could be used to develop further treatment guidelines for adult patients with UVFMI at a speech clinic.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"53 5","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139124170","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth
Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.
{"title":"Reliability of running parameters using fitness watches synced with accelerometers during outdoor runs","authors":"Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth","doi":"10.12982/jams.2024.019","DOIUrl":"https://doi.org/10.12982/jams.2024.019","url":null,"abstract":"Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"51 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120583","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
R. Cressey, Sudalak Sankunkit, Chonnipa Chaovatin, Natteewan Doungjinda, A. Lungkaphin
Background: Although atorvastatin is commonly used as a hypolipidemic agent, it confers many health benefits in which the underlying mechanisms are not fully understood. We have previously shown that combined treatment of atorvastatin and insulin effectively restored renal function of streptozotocin (STZ)-induced diabetic rats; nevertheless, the underlying mechanism was not known. Objective: To determine whether the reno-protective effect of atorvastatin and insulin is mediated through its impact on autophagy. Materials and methods: Markers of autophagy, LC3, and p62/SQSTM1, in rat kidney tissues and cell lines treated with atorvastatin and/or insulin were determined by Western blot analysis. Results: Levels of both LC3-I and LC3-II proteins in kidney tissues of STZ-diabetic rats treated with atorvastatin and insulin were significantly increased. The autophagic flux was examined in vitro and showed that high glucose culture conditions suppressed the autophagic flux in kidney cells. Treatment with insulin moderately increased the conversion of LC3-I to LC3-II. Interestingly, atorvastatin increased autophagic flux only in the hyperglycemic but not in the normoglycemic condition. p62/SQSTM1 protein level was decreased in response to high glucose treatment but increased with the addition of insulin and/or atorvastatin. Conclusion: This study has demonstrated that atorvastatin may represent a novel regimen in providing prevention and protection for diabetic nephropathy through the underlying mechanisms of inducing autophagy and p62/SQSTM1.
{"title":"Atorvastatin increases autophagic flux and p62/SQSTM1 of kidney cells in hyperglycemic conditions and treatment in combination with insulin improves renal function of streptozotocin (STZ)-induced diabetic rats","authors":"R. Cressey, Sudalak Sankunkit, Chonnipa Chaovatin, Natteewan Doungjinda, A. Lungkaphin","doi":"10.12982/jams.2024.016","DOIUrl":"https://doi.org/10.12982/jams.2024.016","url":null,"abstract":"Background: Although atorvastatin is commonly used as a hypolipidemic agent, it confers many health benefits in which the underlying mechanisms are not fully understood. We have previously shown that combined treatment of atorvastatin and insulin effectively restored renal function of streptozotocin (STZ)-induced diabetic rats; nevertheless, the underlying mechanism was not known. Objective: To determine whether the reno-protective effect of atorvastatin and insulin is mediated through its impact on autophagy. Materials and methods: Markers of autophagy, LC3, and p62/SQSTM1, in rat kidney tissues and cell lines treated with atorvastatin and/or insulin were determined by Western blot analysis. Results: Levels of both LC3-I and LC3-II proteins in kidney tissues of STZ-diabetic rats treated with atorvastatin and insulin were significantly increased. The autophagic flux was examined in vitro and showed that high glucose culture conditions suppressed the autophagic flux in kidney cells. Treatment with insulin moderately increased the conversion of LC3-I to LC3-II. Interestingly, atorvastatin increased autophagic flux only in the hyperglycemic but not in the normoglycemic condition. p62/SQSTM1 protein level was decreased in response to high glucose treatment but increased with the addition of insulin and/or atorvastatin. Conclusion: This study has demonstrated that atorvastatin may represent a novel regimen in providing prevention and protection for diabetic nephropathy through the underlying mechanisms of inducing autophagy and p62/SQSTM1.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"54 6","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120737","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Benjamaporn Hancharoenkul, Peanchai Khamwong, Ubon Pirunsan, Leonard Joseph
Background: The prevalence rate of work-related musculoskeletal pain (WMSP) among poultry slaughterhouse workers (PSW) has been reported in the shoulder, arm, and hand due to the involvement of repetitive and forceful upper limb movements. An intervention program is needed to reduce upper limb pain and improve upper limb functions among PSW. Objectives: This study aimed to investigate the effectiveness of workplace intervention programs on musculoskeletal pain, upper limb functions, and work ability among PSW. Materials and methods: A total of 48 participants (21 males and 27 females) who met the inclusion criteria were recruited into the study. The participants were allocated into two groups: The workplace intervention group (WIG, N=24; 10 males; 14 females) and the control group (CG, N=24; 11 males; 13 females). The WIG performed the exercise training with elastic resistance bands (ERB) and stretching exercises for eight weeks, and the CG did not perform any activity. The Visual Analogue Scale (VAS), shoulder reach flexibility test, active range of motion (AROM), the disability of the Arm, Shoulder, and Hand (KKU-DASH), and Thai Work Ability Index (Thai WAI) were used as outcome evaluations. The two-way analyses of variance (ANOVAs) with repeated measures (group x time) were used for statistical analyses, and the statistical significance was set at p<0.05. Results: Approximately 79.1% (N=19) of the participants in WIG reported significantly decreased pain intensity of upper limb 3.06 (0.83 to -5.4) in the right side (p<0.01) and 1.96 (1.6 to -5.6) in the left side (p<0.001) after the 8-week intervention. Meanwhile, shoulder flexibility in WIG significantly increased (p<0.001) to around 3.55 cm. (0.67 to 8.20) on the right side and 5.61 cm. (2.0 to 10.67) on the left side. For AROM in WIG, neck flexion, lateral neck flexion, neck rotation, and left shoulder flexion significantly increased (p<0.05), as well as KKU-DASH and Thai WAI scores (p<0.001). There was no significant difference within-group in all variables in CG. Conclusion: The workplace intervention program significantly reduced upper limb pain and increased neck movement and shoulder flexion among PSW. The training programs also improved work ability and reduced disability with upper extremity musculoskeletal conditions among PSW.
{"title":"The effects of workplace intervention programs to manage work-related musculoskeletal pain among poultry slaughterhouse workers: A randomized controlled trial","authors":"Benjamaporn Hancharoenkul, Peanchai Khamwong, Ubon Pirunsan, Leonard Joseph","doi":"10.12982/jams.2024.002","DOIUrl":"https://doi.org/10.12982/jams.2024.002","url":null,"abstract":"Background: The prevalence rate of work-related musculoskeletal pain (WMSP) among poultry slaughterhouse workers (PSW) has been reported in the shoulder, arm, and hand due to the involvement of repetitive and forceful upper limb movements. An intervention program is needed to reduce upper limb pain and improve upper limb functions among PSW. Objectives: This study aimed to investigate the effectiveness of workplace intervention programs on musculoskeletal pain, upper limb functions, and work ability among PSW. Materials and methods: A total of 48 participants (21 males and 27 females) who met the inclusion criteria were recruited into the study. The participants were allocated into two groups: The workplace intervention group (WIG, N=24; 10 males; 14 females) and the control group (CG, N=24; 11 males; 13 females). The WIG performed the exercise training with elastic resistance bands (ERB) and stretching exercises for eight weeks, and the CG did not perform any activity. The Visual Analogue Scale (VAS), shoulder reach flexibility test, active range of motion (AROM), the disability of the Arm, Shoulder, and Hand (KKU-DASH), and Thai Work Ability Index (Thai WAI) were used as outcome evaluations. The two-way analyses of variance (ANOVAs) with repeated measures (group x time) were used for statistical analyses, and the statistical significance was set at p<0.05. Results: Approximately 79.1% (N=19) of the participants in WIG reported significantly decreased pain intensity of upper limb 3.06 (0.83 to -5.4) in the right side (p<0.01) and 1.96 (1.6 to -5.6) in the left side (p<0.001) after the 8-week intervention. Meanwhile, shoulder flexibility in WIG significantly increased (p<0.001) to around 3.55 cm. (0.67 to 8.20) on the right side and 5.61 cm. (2.0 to 10.67) on the left side. For AROM in WIG, neck flexion, lateral neck flexion, neck rotation, and left shoulder flexion significantly increased (p<0.05), as well as KKU-DASH and Thai WAI scores (p<0.001). There was no significant difference within-group in all variables in CG. Conclusion: The workplace intervention program significantly reduced upper limb pain and increased neck movement and shoulder flexion among PSW. The training programs also improved work ability and reduced disability with upper extremity musculoskeletal conditions among PSW.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"54 1","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120738","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth
Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.
{"title":"Reliability of running parameters using fitness watches synced with accelerometers during outdoor runs","authors":"Jitapa Chawawisuttikool, Chatchai Phirawatthakul, Warintun Thomchaita, Chatchai Tieachanpan, O. Prasartwuth","doi":"10.12982/jams.2024.019","DOIUrl":"https://doi.org/10.12982/jams.2024.019","url":null,"abstract":"Background: To prevent running related injuries and return to sport activities, monitoring the running dynamic parameters (cadence, stride length, ground contact time and vertical oscillation) especially outdoor running is crucial. Previous studies investigated the reliability of these parameters in laboratory settings. However, the nature of outdoor runs is different (curve, uphill, other runners, etc.) and challenging in terms of equipment (simple) and environments (grass, asphalt, rubber, etc.). Therefore, the reliability of these parameters using a fitness watch synced with accelerometer needed to be investigated. Objective: To investigate the reliability of running parameters measured using fitness watches and accelerometers during outdoor runs. Materials and methods: 30 healthy volunteers (age 25.8±9.6 years, height 167.2±9.3 cm, weight 62.4±14.2 kg, and body mass index 22.2±3.8 kg/m2) participated in the study. They wore a fitness watch and attached a synced accelerometer at their pants. They completed 2 running laps (800 meters each) at their comfortable speeds. Resting periods were provided between laps. To control the speed for the second lap, the watch was set the maximum and minimum speed and set vibration and sound alarm mode. Running parameters include cadence, stride length, vertical oscillation, and ground contact time. Results: The reliability of the four running parameters (cadence, stride length, ground contact time, and vertical oscillation), indicated by the intraclass correlation coefficients (ICC (3,k)) was 0.94, 0.97, 0.98 and 0.99, respectively. Very high reliability values were confirmed. Conclusion: Using a fitness watch synced with an accelerometer during outdoor runs, running dynamic parameters (cadence, stride length, ground contact time, and vertical oscillation) illustrated very high levels of reliability.","PeriodicalId":298884,"journal":{"name":"Journal of Associated Medical Sciences","volume":"51 10","pages":""},"PeriodicalIF":0.0,"publicationDate":"2024-01-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"139120765","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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