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Mobilizing data during a crisis: Building rapid evidence pipelines using multi-institutional real world data 在危机期间调动数据:利用多机构真实世界数据建立快速证据管道
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-03-25 DOI: 10.1016/j.hjdsi.2024.100738
Jayson S. Marwaha , Maren Downing , John Halamka , Amy Abernethy , Joseph B. Franklin , Brian Anderson , Isaac Kohane , Kavishwar Wagholikar , John Brownstein , Melissa Haendel , Gabriel A. Brat

The COVID-19 pandemic generated tremendous interest in using real world data (RWD). Many consortia across the public and private sectors formed in 2020 with the goal of rapidly producing high-quality evidence from RWD to guide medical decision-making, public health priorities, and more. Experiences were gathered from five large consortia on rapid multi-institutional evidence generation during the COVID-19 pandemic. Insights have been compiled across five dimensions: consortium composition, governance structure and alignment of priorities, data sharing, data analysis, and evidence dissemination. The purpose of this piece is to offer guidance on building large-scale multi-institutional RWD analysis pipelines for future public health issues.

The composition of each consortium was largely influenced by existing collaborations. A central set of priorities for evidence generation guided each consortium, however different approaches to governance emerged. Challenges surrounding limited access to clinical data due to various contributors were overcome in unique ways. While all consortia used different methods to construct and analyze patient cohorts ranging from centralized to federated approaches, all proved effective for generating meaningful real-world evidence. Actionable recommendations for clinical practice and public health agencies were made from translating insights from consortium analyses.

Each consortium was successful in rapidly answering questions about COVID-19 diagnosis and treatment despite all taking slightly different approaches to data sharing and analysis. Leveraging RWD, leveraged in a manner that applies scientific rigor and transparency, can complement higher-level evidence and serve as an important adjunct to clinical trials to quickly guide policy and critical care, especially for a pandemic response.

COVID-19 大流行引起了人们对使用真实世界数据 (RWD) 的极大兴趣。2020 年,公共和私营部门成立了许多联盟,目标是从 RWD 中快速生成高质量的证据,以指导医疗决策、公共卫生优先事项等。我们收集了五个大型联盟在 COVID-19 大流行期间快速生成多机构证据的经验。这些经验包括五个方面:联合体的组成、管理结构和优先事项的协调、数据共享、数据分析和证据传播。这篇文章的目的是为未来的公共卫生问题提供建立大规模多机构 RWD 分析管道的指导。每个联盟的组成在很大程度上都受到了现有合作的影响。每个联盟都有一套核心的证据生成优先事项,但出现了不同的管理方法。各联盟以独特的方式克服了因不同贡献者而导致的临床数据获取受限的挑战。虽然所有联盟都采用了不同的方法来构建和分析患者队列,从集中式方法到联合式方法,但所有方法都被证明能有效生成有意义的真实世界证据。尽管各联盟采用的数据共享和分析方法略有不同,但它们都成功地快速回答了有关 COVID-19 诊断和治疗的问题。以科学严谨和透明的方式利用 RWD,可以补充更高层次的证据,并作为临床试验的重要辅助手段,快速指导政策和关键护理,尤其是在大流行应对中。
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引用次数: 0
The next decade of Healthcare 医疗保健的下一个十年
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-03-01 DOI: 10.1016/j.hjdsi.2024.100737
Jennifer P. Stevens, Amol Navathe, Sachin Jain
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引用次数: 0
Building a post-myocardial infarction discharge intervention program for Hispanic patients 为西班牙裔患者制定心肌梗死出院后干预计划
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-03-01 DOI: 10.1016/j.hjdsi.2023.100730
Jonathan Ludmir , Giselle A. Suero-Abreu , Ayda Gonzalez de la Nuez , Martin Robles , Malissa J. Wood , Marcela G. del Carmen , Jason H. Wasfy

Hispanic patients disproportionally suffer from disparities in care delivery in the setting of acute myocardial infarction (AMI). More specifically, Hispanic patients have higher 30-day readmission rates post-AMI and are less likely to be referred to cardiac rehab. Because of the challenges Hispanic patients face with post-AMI care, the Hispanic Acute Myocardial Infarction Discharge Intervention Study (HAMIDI) was launched to provide a culturally sensitive discharge framework to improve readmission and mortality rates in this population. Patients enrolled in this study participate in a comprehensive post-discharge program involving follow-up with a Spanish-speaking cardiologist, a two-part educational virtual group visit program, and access to support throughout the study. During the initial year of the study, 35 patients enrolled and successfully participated in the program. This case study reviews the implementation process, initial outcomes, challenges, and future plans of the program.

在急性心肌梗死(AMI)的治疗过程中,西语裔患者在护理服务方面遭受的不平等待遇尤为严重。更具体地说,西班牙裔患者在急性心肌梗死后 30 天内的再入院率较高,而且不太可能被转介到心脏康复中心。由于西语裔患者在急性心肌梗死后护理方面面临挑战,因此发起了西语裔急性心肌梗死出院干预研究(HAMIDI),旨在提供一个文化敏感的出院框架,以改善这一人群的再入院率和死亡率。参加该研究的患者出院后将参加一项综合计划,包括由讲西班牙语的心脏病专家进行随访、由两部分组成的教育性虚拟小组访问计划,以及在整个研究过程中获得支持。在研究的最初一年,有 35 名患者注册并成功参与了该计划。本案例研究回顾了该计划的实施过程、初步成果、挑战和未来计划。
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引用次数: 0
Acknowledgments to our reviewers in 2023 鸣谢 2023 年的审查员
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-02-27 DOI: 10.1016/j.hjdsi.2024.100736
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引用次数: 0
Public health and social entrepreneurs as activators of equitable health ecosystems 公共卫生和社会企业家作为公平健康生态系统的激活者
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-02-24 DOI: 10.1016/j.hjdsi.2024.100735
Maningbè Keita Fakeye , Jessica Overman , Jay Bhatt , Molly K. O'Donnell , Joanna Burleson

Objectives

To describe approaches that public health and social entrepreneurs take to address health equity, and identify strategies for equitable collaborations with these entrepreneurs.

Methods

We leveraged data from semi-structured interviews, conducted August to October 2022, with 20 public health and social entrepreneurs who focus on drivers of health and health equity. Two researchers employed content analysis, guided by a prior framework.

Results

To support health equity, public health and social entrepreneurs: center equity, critique biases, innovate for inclusion, engage translational expertise, catalyze capacity, and activate equitable systems. Equitable collaborations are supported by re-examining roles, de-conflicting organizational barriers, prioritizing representation, mitigating bias in generating evidence, and employing equitable capital.

Conclusions

Public health and social entrepreneurs can uplift equity across health service design and delivery. More equitable collaborations can advance this work.

目标描述公共卫生和社会企业家为解决健康公平问题所采取的方法,并确定与这些企业家开展公平合作的策略。方法我们利用了 2022 年 8 月至 10 月对 20 名关注健康和健康公平驱动因素的公共卫生和社会企业家进行的半结构化访谈数据。结果为支持健康公平,公共卫生和社会企业家:以公平为中心,批判偏见,创新包容,利用转化专业知识,促进能力,激活公平系统。通过重新审视角色、消除组织障碍、优先考虑代表性、减少证据生成过程中的偏见以及使用公平资本来支持公平合作。更公平的合作可以推动这项工作。
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引用次数: 0
Are disparities in mental health care for Medicaid beneficiaries lower in managed care? 在管理式医疗中,医疗补助受益人的心理健康护理差异是否较小?
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-02-02 DOI: 10.1016/j.hjdsi.2024.100734
Joshua Breslau , Bing Han , Jonathan S. Levin , Julie Lai , Hao Yu

Background

There are large and persistent racial and ethnic disparities in the use of mental health care in the United States. Medicaid managed care plans have the potential to reduce racial and ethnic disparities in use of mental health care through monitoring of need and active management of use of services across the populations they cover. This study compares racial and ethnic disparities among Medicaid beneficiaries in managed care with those not in managed care.

Methods

We compared Medicaid beneficiaries enrolled health maintenance organizations (HMOs) with those in fee-for-service (FFS) using data from the 2007–2015 Medical Expenditure Panel Survey (N = 26,113). We specified two-part propensity score adjusted models to estimate differences in mental health related emergency department visits, hospital stays, prescription fills, and outpatient visits overall and by race/ethnicity.

Results

HMO enrollment was associated with lower odds of having a mental health prescription (OR = 0.86, 95 % CI 0.78–0.96) or outpatient visit (OR = 0.82 95 % CI 0.73–0.92). These differences were similar across racial and ethnic groups or larger among Non-Hispanic Black and Hispanic beneficiaries than among Non-Hispanic White beneficiaries.

Conclusions

Medicaid managed care has not improved the inequitable allocation of mental health care across racial and ethnic groups. Explicit attention to monitoring of racial and ethnic differences in use of mental health care in Medicaid managed care is warranted.

Implications

Improvement in racial and ethnic disparities in mental health care in Medicaid manage care is unlikely to occur without targeted accountability mechanisms, such as required reporting or other contracting requirements.

背景在美国,种族和民族之间在使用心理健康护理方面存在着巨大而持久的差异。医疗补助管理性护理计划通过对其覆盖人群的需求进行监测和对服务使用情况进行积极管理,有可能减少心理健康护理使用中的种族和民族差异。本研究比较了接受管理式医疗服务和未接受管理式医疗服务的医疗补助受益人之间的种族和民族差异。方法我们利用 2007-2015 年医疗支出小组调查(N=26113)的数据,比较了加入健康维护组织(HMO)和付费服务(FFS)的医疗补助受益人。我们建立了两部分倾向得分调整模型,以估算与精神健康相关的急诊就诊、住院、处方开具和门诊就诊的总体差异,以及不同种族/族裔之间的差异。这些差异在不同种族和民族群体中相似,或在非西班牙裔黑人和西班牙裔受益人中大于非西班牙裔白人受益人。如果没有有针对性的问责机制,如要求报告或其他合同要求,医疗补助管理性医疗中心理健康护理的种族和民族差异就不可能得到改善。
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引用次数: 0
Training pediatric physicians and staff to obtain data from the electronic health record 培训儿科医师和工作人员从电子健康记录中获取数据
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-01-08 DOI: 10.1016/j.hjdsi.2023.100733
Tiranun Rungvivatjarus , Amy Z. Chong , Aarti Patel , Manaswitha Khare , Mario Bialostozky , Cynthia L. Kuelbs

Electronic health records (EHRs) have provided physicians with user-friendly self-service reporting tools to extract patient data from the EHR. Despite such benefits, physician training on how to use these tools has been limited. At our institution, physicians were faced with prolonged wait time for EHR data extraction requests and were unaware of self-service reporting tool availability in the EHR. Our goal was to develop an EHR data reporting curriculum for physicians and staff and examine the effectiveness of such training. In 2019, physician informaticists developed two interactive sessions to train physicians and staff on self-service reporting tools (Epic® SlicerDicer and Reporting Workbench (RWB)) available in our tertiary children’s hospital EHR. We assessed participants' knowledge, confidence, and tool utilization before, after, and 3-months post training via survey. Training sessions occurred between April and August 2021. Thirty-six participants completed the study, with 25 surveys collected immediately post and 22 surveys collected at 3-months post training. Data literacy knowledge pre-test average score improved from 62% to 93% (p < 0.05) immediately post-session and 74% at 3-months post assessment (p = 0.05). Regular tool utilization increased from 29% (RWB) and 34% (SlicerDicer) pre-session to 56% and 44% at 3-months post, respectively. Participants reported increased confidence in performing SlicerDicer model selection, criteria selection, and data visualization as well as RWB report navigation, report creation, report visualization, and describing report’s benefits/limitations. Ultimately, physician and staff self-service reporting tools training were effective in increasing data literacy knowledge, tool utilization, and confidence.

电子病历(EHR)为医生提供了用户友好的自助报告工具,以便从 EHR 中提取患者数据。尽管有这些好处,但对医生如何使用这些工具的培训却很有限。在我们所在的机构,医生们面临着漫长的 EHR 数据提取请求等待时间,而且不知道 EHR 中是否有自助报告工具。我们的目标是为医生和员工开发电子病历数据报告课程,并检查此类培训的效果。2019 年,医生信息学家开发了两节互动课程,对医生和员工进行有关自助报告工具(Epic® SlicerDicer 和 Reporting Workbench (RWB))的培训,这些工具可在我们的三级儿童医院 EHR 中使用。我们在培训前、培训后和培训后 3 个月通过调查对参与者的知识、信心和工具使用情况进行了评估。培训课程于 2021 年 4 月至 8 月间进行。36 名参与者完成了研究,其中 25 份调查问卷是在培训后立即收集的,22 份调查问卷是在培训后 3 个月收集的。数据扫盲知识测试前的平均得分从 62% 提高到培训后的 93%(p < 0.05),培训后 3 个月的平均得分为 74%(p = 0.05)。常规工具的使用率分别从课前的 29% (RWB)和 34%(SlicerDicer)提高到课后 3 个月的 56% 和 44%。参加者表示,在进行 SlicerDicer 模型选择、标准选择和数据可视化以及 RWB 报告导航、报告创建、报告可视化和报告优点/局限性描述方面的信心都有所增强。最终,医生和员工自助报告工具培训有效地提高了数据扫盲知识、工具使用率和信心。
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引用次数: 0
Innovation in public delivery systems: How one safety net hospital implemented new heart monitoring technology 公共服务系统的创新:一家安全网医院如何实施新的心脏监测技术
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2024-01-05 DOI: 10.1016/j.hjdsi.2023.100732
Margae Knox , Beatrice Huang , Rachel Willard-Grace , George Su

This case study examines how a public delivery system hospital implemented a heart monitoring patch in place of existing electrocardiogram (ECG) monitoring by pursuing a holistic value proposition. For example, leaders identified opportunity costs embedded in the existing ECG monitoring staffing. Stakeholders also rallied around values such as patient safety, patient experience, and quality of care.

Implementation also benefited from external philanthropic and industry partnerships, which facilitated a pilot period to implement new workflows, demonstrate proof-of-concept, and evaluate process improvements.

Despite implementation success, ongoing procurement and reimbursement challenges demonstrate the messiness of innovation, even after reaching a “maintenance” phase. Availability of patient-facing material in multiple languages is one example of an implementation gap in safety net settings. New policies by health systems, payers, and others are needed to establish pathways for future high-value innovations.

本案例研究探讨了一家公立医疗系统医院如何通过追求整体价值主张来实施心脏监测贴片,以取代现有的心电图(ECG)监测。例如,领导者发现了现有心电图监测人员配置中蕴含的机会成本。利益相关者还围绕患者安全、患者体验和护理质量等价值观展开合作。实施工作还得益于外部慈善机构和行业合作,这有助于在试点期间实施新的工作流程、演示概念验证和评估流程改进。尽管实施工作取得了成功,但持续的采购和报销挑战表明,即使在进入 "维护 "阶段后,创新工作也是一团糟。以多种语言提供面向患者的资料就是安全网环境中实施差距的一个例子。医疗系统、支付方等需要制定新政策,为未来的高价值创新开辟道路。
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引用次数: 0
Large language models as a source of health information: Are they patient-centered? A longitudinal analysis 作为健康信息来源的大型语言模型:它们以患者为中心吗?纵向分析。
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2023-12-22 DOI: 10.1016/j.hjdsi.2023.100731
Kanhai Amin , Rushabh Doshi , Howard P. Forman
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引用次数: 0
Optimizing care delivery in expanding health systems: Views from clinical leaders 在不断扩大的卫生系统中优化保健服务:来自临床领导者的观点
IF 2.5 4区 医学 Q3 HEALTH POLICY & SERVICES Pub Date : 2023-11-23 DOI: 10.1016/j.hjdsi.2023.100722
Adrian Diaz , Karan R. Chhabra , Mary E. Byrnes , Abishek Rajkumar , Phillip Yang , Andrew Ibrahim , Justin B. Dimick , Hari Nathan

Introduction

In response to intense market pressures, many hospitals have consolidated into systems. However, evidence suggests that consolidation has not led to the improvements in clinical quality promised by proponents of mergers. The challenges to delivering care within expanding health systems and the opportunities posed to surgical leaders remains largely unexplored.

Methods

Semistructured interviews with 30 surgical leaders at teaching hospitals affiliated with health systems from August–December 2019. Interviews were transcribed verbatim and coded in an iterative process using MaxQDA software. Attitudes and strategies toward redesigning health care delivery across expanding systems were analyzed using thematic analysis.

Results

Leaders reported challenges to redesigning care delivery across the system ranging from resource constraints (e.g. hospital beds and operating rooms) to evolving market demands (e.g., patient preferences to receive care close to home). However, participants also highlighted that system expansion provided multiple opportunities to increase access (e.g. decant low-complexity care to affiliated centers) and improve quality of care (e.g. standardize best practices) for diverse populations including the potential to leverage their health system to expand access and improve quality.

Conclusions

Though evidence suggests that hospital consolidation has not led to redesigned care delivery or improved clinical quality at a national level, leaders are pursuing varying sets of strategies aimed at leveraging system expansion in order to improve access and quality of care.

为了应对巨大的市场压力,许多医院已整合成系统。然而,有证据表明,合并并没有带来合并支持者所承诺的临床质量的改善。在不断扩大的卫生系统内提供护理的挑战以及外科领导者面临的机遇在很大程度上仍未得到探索。方法2019年8月- 12月对30名卫生系统附属教学医院外科负责人进行半结构化访谈。使用MaxQDA软件逐字记录访谈,并在迭代过程中进行编码。利用专题分析分析了在不断扩大的系统中重新设计卫生保健服务的态度和策略。领导者报告了在整个系统中重新设计护理服务的挑战,从资源限制(例如医院床位和手术室)到不断变化的市场需求(例如患者偏好在家附近接受护理)。然而,与会者还强调,系统扩展为不同人群提供了多种机会来增加可及性(例如,将低复杂性的护理转移到附属中心)和提高护理质量(例如,使最佳做法标准化),包括利用其卫生系统扩大可及性和提高质量的潜力。虽然有证据表明,医院合并并没有导致重新设计的医疗服务或提高临床质量在国家层面上,领导人正在追求不同的策略,旨在利用系统扩展,以提高获取和护理质量。
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引用次数: 0
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Healthcare-The Journal of Delivery Science and Innovation
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