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Type I Collagen-Targeted PET Imaging in Idiopathic Pulmonary Fibrosis: First-in-Human Studies 特发性肺纤维化的I型胶原靶向PET成像:首次人体研究
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-06-04 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7349
S. Montesi, D. Izquierdo-Garcia, Pauline Désogère, E. Abston, L. Liang, S. Digumarthy, R. Seethamraju, M. Lanuti, P. Caravan, C. Catana
{"title":"Type I Collagen-Targeted PET Imaging in Idiopathic Pulmonary Fibrosis: First-in-Human Studies","authors":"S. Montesi, D. Izquierdo-Garcia, Pauline Désogère, E. Abston, L. Liang, S. Digumarthy, R. Seethamraju, M. Lanuti, P. Caravan, C. Catana","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7349","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a7349","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"104 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-06-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"134222832","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Wnt/Planar Cell Polarity Pathway Signaling Between Endothelial Cell and Pericyte-Like Smooth Muscle Cells Enhance Vascular Repaving in an Acellular Lung Scaffold 内皮细胞和周细胞样平滑肌细胞之间的Wnt/平面细胞极性信号通路促进无细胞肺支架血管重建
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2554
M. Ho, K. Chaudhary, D. Stewart
{"title":"Wnt/Planar Cell Polarity Pathway Signaling Between Endothelial Cell and Pericyte-Like Smooth Muscle Cells Enhance Vascular Repaving in an Acellular Lung Scaffold","authors":"M. Ho, K. Chaudhary, D. Stewart","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2554","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2554","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"369 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"121735709","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Context-Specific Maturation of Lung Progenitors Is Directed by Lung Matrices and Vascular Cell-Derived Extracellular Vesicles 肺祖细胞的环境特异性成熟是由肺基质和血管细胞衍生的细胞外囊泡引导的
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2551
M. Ho, K. R. Chaudhary, D. Stewart
{"title":"Context-Specific Maturation of Lung Progenitors Is Directed by Lung Matrices and Vascular Cell-Derived Extracellular Vesicles","authors":"M. Ho, K. R. Chaudhary, D. Stewart","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2551","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2551","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"49 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130741753","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Development of Hydrogel Bioinks and 3D Bioprinting Techniques to Support Extended 3D Lung Tissue Culture In Vitro 水凝胶生物墨水和3D生物打印技术的发展，以支持体外扩展的3D肺组织培养
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2552
K. E. Bailey, N. Darling, D. Velu, Tyler J D'Ovidio, M. Floren, S. Lammers, K. Stenmark, Chelsea M. Magin
{"title":"Development of Hydrogel Bioinks and 3D Bioprinting Techniques to Support Extended 3D Lung Tissue Culture In Vitro","authors":"K. E. Bailey, N. Darling, D. Velu, Tyler J D'Ovidio, M. Floren, S. Lammers, K. Stenmark, Chelsea M. Magin","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2552","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2552","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"35 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133487072","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
FAK-Related Non-Kinase Modulates Matrix Remodeling, Fibroblast Mechanosensing, and Myofibroblast Survival fak相关非激酶调节基质重塑、成纤维细胞力学感知和肌成纤维细胞存活
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2546
P. Che, X.-K. Zhao, L. Yu, M. Olman, Q. Ding
{"title":"FAK-Related Non-Kinase Modulates Matrix Remodeling, Fibroblast Mechanosensing, and Myofibroblast Survival","authors":"P. Che, X.-K. Zhao, L. Yu, M. Olman, Q. Ding","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2546","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2546","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"56 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125964263","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Recellularization of Decellularized Mouse Lung Airways Using Negative Pressure Directed Cell Delivery 负压定向细胞输送对脱细胞小鼠肺气道的再细胞化
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2558
M. Ahmadipour, F. Aoki, G. Karoubi, Thomas K. Waddell
{"title":"Recellularization of Decellularized Mouse Lung Airways Using Negative Pressure Directed Cell Delivery","authors":"M. Ahmadipour, F. Aoki, G. Karoubi, Thomas K. Waddell","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2558","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2558","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"14 1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"131056229","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Single Cell RNA Sequencing of Human Lung Explants Identifies the Cell-Specific Contributions of Extracellular Matrix-Related Gene Expression 人肺外植体的单细胞RNA测序鉴定细胞外基质相关基因表达的细胞特异性贡献
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2550
S. Frías, T. Adams, Jonas Schupp, S. Chu, N. Neumark, F. Ahangari, G. Waskho, B. Raby, N. Kaminski, I. Rosas
{"title":"Single Cell RNA Sequencing of Human Lung Explants Identifies the Cell-Specific Contributions of Extracellular Matrix-Related Gene Expression","authors":"S. Frías, T. Adams, Jonas Schupp, S. Chu, N. Neumark, F. Ahangari, G. Waskho, B. Raby, N. Kaminski, I. Rosas","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2550","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2550","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"8 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126299480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Lung Derived ECM/Polymer Composite Substrates to Investigate Composition and Stiffness-Dependent Cell-ECM Interactions 肺源性ECM/聚合物复合基质研究成分和刚度依赖细胞-ECM相互作用
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2553
R. Pouliot, A. Bhattacharyya, Juan J. Uriarte, K. Xia, D.J. Weiss
{"title":"Lung Derived ECM/Polymer Composite Substrates to Investigate Composition and Stiffness-Dependent Cell-ECM Interactions","authors":"R. Pouliot, A. Bhattacharyya, Juan J. Uriarte, K. Xia, D.J. Weiss","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2553","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2553","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"45 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133756050","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
α-TAT1 Promotes Myofibroblast Activation and Lung Fibrosis Via Microtubule-Dependent Mechanotransduction Pathways α-TAT1通过微管依赖的机械转导途径促进肌成纤维细胞活化和肺纤维化
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2561
A. Santos
{"title":"α-TAT1 Promotes Myofibroblast Activation and Lung Fibrosis Via Microtubule-Dependent Mechanotransduction Pathways","authors":"A. Santos","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2561","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2561","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"126020151","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Role of PGE Synthase Expression by Asthmatic Bronchial Epithelial Cells in Regulating Lung Fibroblast Extracellular Matrix Expression and Fibroblast-to-Myofibroblast Transition 哮喘支气管上皮细胞表达PGE合成酶在调节肺成纤维细胞胞外基质表达和成纤维细胞向肌成纤维细胞转化中的作用
A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS
Pub Date : 2019-05-01 DOI: 10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2548
S. R. Reeves, K. Barrow, L. M. Rich, M. White, J. Debley
{"title":"Role of PGE Synthase Expression by Asthmatic Bronchial Epithelial Cells in Regulating Lung Fibroblast Extracellular Matrix Expression and Fibroblast-to-Myofibroblast Transition","authors":"S. R. Reeves, K. Barrow, L. M. Rich, M. White, J. Debley","doi":"10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2548","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2019.199.1_meetingabstracts.a2548","url":null,"abstract":"","PeriodicalId":301466,"journal":{"name":"A107. ENGINEERED AND REMODELLED MATRIX COMPARTMENTS","volume":"20 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2019-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125055537","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
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