首页 > 最新文献

Case Reports in Orthopedics最新文献

英文 中文
Massive Osteolysis in a Modern Total Knee Prosthesis. 现代全膝关节假体大量骨溶解。
Q4 ORTHOPEDICS Pub Date : 2021-10-20 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5507932
Emmanuel Gibon, Jacquelyn A Knapik, Hari K Parvataneni
Case An 82-year-old woman underwent right total knee replacement with a sequentially irradiated and annealed highly cross-linked polyethylene insert. At 9 years, she was found to have a massive femoral osteolysis with an impending fracture. Conclusion This case demonstrates a rare occurrence of massive femoral osteolysis, requiring revision surgery, with a sequentially irradiated and annealed highly cross-linked polyethylene.
病例:一名82岁的女性接受了右全膝关节置换术,采用连续辐照和退火的高交联聚乙烯置入物。在9岁时,她被发现有大量的股骨骨溶解和即将发生的骨折。结论:本病例为罕见的大量股骨骨溶解,需要进行翻修手术,并进行连续照射和高交联聚乙烯退火。
{"title":"Massive Osteolysis in a Modern Total Knee Prosthesis.","authors":"Emmanuel Gibon, Jacquelyn A Knapik, Hari K Parvataneni","doi":"10.1155/2021/5507932","DOIUrl":"https://doi.org/10.1155/2021/5507932","url":null,"abstract":"Case An 82-year-old woman underwent right total knee replacement with a sequentially irradiated and annealed highly cross-linked polyethylene insert. At 9 years, she was found to have a massive femoral osteolysis with an impending fracture. Conclusion This case demonstrates a rare occurrence of massive femoral osteolysis, requiring revision surgery, with a sequentially irradiated and annealed highly cross-linked polyethylene.","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"5507932"},"PeriodicalIF":0.0,"publicationDate":"2021-10-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8550852/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39832663","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Spontaneous Distal Extrusion of Kuntscher Intramedullary Nail. Kuntscher髓内钉自发性远端挤压。
Q4 ORTHOPEDICS Pub Date : 2021-10-18 eCollection Date: 2021-01-01 DOI: 10.1155/2021/5587325
W B Teh, R Kuharajan, A H Noor Shafika, I G Nur Azhani

Migration of femoral Kuntscher intramedullary nail (K-nail) proximally or distally within the femoral medullary cavity is a well-known documented complication, but spontaneous extrusion of a distally migrated K-nail is a rare complication. This is a case report of a 33-year-old lady who complained of sudden onset left knee pain and presented with spontaneous extrusion of a Kuntscher nail 12 years postinsertion. She underwent a successful K-nail removal surgery and showed a good clinical outcome after 6 months of outpatient follow-up.

股骨Kuntscher髓内钉(K-nail)在股骨髓腔内近端或远端移位是一种众所周知的并发症,但远端移位k -钉的自发挤压是一种罕见的并发症。这是一个33岁的病例报告,她主诉突然发作的左膝疼痛,并在插入Kuntscher钉子12年后出现自发性挤压。她接受了成功的k -甲去除手术,并在6个月的门诊随访后显示出良好的临床结果。
{"title":"Spontaneous Distal Extrusion of Kuntscher Intramedullary Nail.","authors":"W B Teh,&nbsp;R Kuharajan,&nbsp;A H Noor Shafika,&nbsp;I G Nur Azhani","doi":"10.1155/2021/5587325","DOIUrl":"https://doi.org/10.1155/2021/5587325","url":null,"abstract":"<p><p>Migration of femoral Kuntscher intramedullary nail (K-nail) proximally or distally within the femoral medullary cavity is a well-known documented complication, but spontaneous extrusion of a distally migrated K-nail is a rare complication. This is a case report of a 33-year-old lady who complained of sudden onset left knee pain and presented with spontaneous extrusion of a Kuntscher nail 12 years postinsertion. She underwent a successful K-nail removal surgery and showed a good clinical outcome after 6 months of outpatient follow-up.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"5587325"},"PeriodicalIF":0.0,"publicationDate":"2021-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8545563/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39566083","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
'Within Ring' Concept Treatment for Displaced H-Shaped Type IVb Fragility Fractures of the Pelvis. “环内”概念治疗移位的h型IVb型骨盆脆性骨折。
Q4 ORTHOPEDICS Pub Date : 2021-10-15 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6864910
Yohei Yanagisawa, Yusuke Eda, Shotaro Teruya, Hisanori Gamada, Masashi Yamazaki

Introduction: Sacroiliac rod fixation (SIRF) preserves the mobility of L5/S1 (lumber in the pelvis), as a surgical procedure for high-energy pelvic ring fractures. The concept of SIRF method without pedicle screws into L4 and L5 is called 'within ring' concept. Case Presentation. We report here the clinical results of 'within ring' concept treatment with sacroiliac rod fixation for a case of displaced H-shaped Rommens and Hofmann classification type IVb fragility fractures of the pelvis (FFP), which A 79-year-old woman had been difficult to walk due to pain that had been prolonged for more than one month since her injury. The patient was successfully treated with SIRF, no pain waking with a walking stick and returned to most social activities including living independently within 6 months of the operation.

Conclusion: SIRF is useful because it can preserve the mobility in the lumbar pelvis; not including the lumbar spine in the fixation range like spino pelvic fixation is a simple, safe, and low-invasive internal fixation method for displaced H-shaped type IVb fragility fractures of the pelvis.

介绍:骶髂棒固定(SIRF)作为一种治疗高能骨盆环骨折的手术方法,可保留L5/S1(骨盆内木材)的活动能力。没有椎弓根螺钉进入L4和L5的SIRF方法的概念被称为“环内”概念。案例演示。我们在此报告一例移位的h型Rommens和Hofmann分类IVb型骨盆脆性骨折(FFP)的“环内”概念治疗与骶髂棒固定的临床结果,该病例是一名79岁的女性,由于受伤后持续一个多月的疼痛而难以行走。患者经SIRF治疗成功,手术后6个月内,患者不再用手杖痛醒,并恢复了大部分社会活动,包括独立生活。结论:SIRF能保持腰椎骨盆的活动能力;不将腰椎包括在固定范围内如脊柱骨盆固定是一种简单、安全、低侵入性的治疗移位的h型IVb型骨盆脆性骨折的内固定方法。
{"title":"'Within Ring' Concept Treatment for Displaced H-Shaped Type IVb Fragility Fractures of the Pelvis.","authors":"Yohei Yanagisawa,&nbsp;Yusuke Eda,&nbsp;Shotaro Teruya,&nbsp;Hisanori Gamada,&nbsp;Masashi Yamazaki","doi":"10.1155/2021/6864910","DOIUrl":"https://doi.org/10.1155/2021/6864910","url":null,"abstract":"<p><strong>Introduction: </strong>Sacroiliac rod fixation (SIRF) preserves the mobility of L5/S1 (lumber in the pelvis), as a surgical procedure for high-energy pelvic ring fractures. The concept of SIRF method without pedicle screws into L4 and L5 is called 'within ring' concept. <i>Case Presentation</i>. We report here the clinical results of 'within ring' concept treatment with sacroiliac rod fixation for a case of displaced H-shaped Rommens and Hofmann classification type IVb fragility fractures of the pelvis (FFP), which A 79-year-old woman had been difficult to walk due to pain that had been prolonged for more than one month since her injury. The patient was successfully treated with SIRF, no pain waking with a walking stick and returned to most social activities including living independently within 6 months of the operation.</p><p><strong>Conclusion: </strong>SIRF is useful because it can preserve the mobility in the lumbar pelvis; not including the lumbar spine in the fixation range like spino pelvic fixation is a simple, safe, and low-invasive internal fixation method for displaced H-shaped type IVb fragility fractures of the pelvis.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6864910"},"PeriodicalIF":0.0,"publicationDate":"2021-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8536442/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39555439","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
Dislocation after Posterior Stabilized Primary Total Knee Replacement: A Rare Complication in Four Cases. 后路稳定全膝关节置换术后脱位:4例罕见并发症。
Q4 ORTHOPEDICS Pub Date : 2021-10-13 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9935401
W Spierenburg, E L A R Mutsaerts, J J A M van Raay

Introduction: Dislocation of a total knee arthroplasty is a rare complication that has rarely been described, while the total knee arthroplasty is frequently performed. From literature, we know patient-related factors, like obesity, neuropsychiatric disease, and severe valgus or varus deformity, are associated with higher risk of dislocation. We show our cases for awareness of the risk factors for surgeons. Case Presentations. We present four patients with a dislocation after a total knee arthroplasty. We compare these case reports with previous literature and show the most important risk factors for these dislocations. In our cases, three of them suffered from obesity, which possibly has contributed to the dislocation. Three patients did have instability which emphasizes the importance of ligament balancing while performing a total knee replacement. In all cases, an exchange of the polyethylene liner was performed.

Conclusion: Implant-related factors and surgical technique as well as patient-related factors can contribute to this uncommon complication. Obesity, neuropsychiatric disorders, and a severe valgus or varus deformity are important patient-related risk factors. Our cases show these risk factors too. Some of these risk factors were encountered as well as other comorbidity factors. Such risk factors must be taken into consideration when deciding whether to perform a total knee arthroplasty. This stresses the importance of patient education and shared decision-making before performing a total knee replacement.

前言:全膝关节置换术脱位是一种罕见的并发症,很少被描述,而全膝关节置换术是经常进行的。从文献中,我们知道与患者相关的因素,如肥胖、神经精神疾病和严重的外翻或内翻畸形,与脱位的高风险相关。我们展示了我们的病例,以提高外科医生对危险因素的认识。例演示。我们提出4例全膝关节置换术后脱位的患者。我们将这些病例报告与以前的文献进行比较,并显示这些脱位的最重要的危险因素。在我们的病例中,其中三人患有肥胖,这可能是导致脱位的原因。三名患者确实有不稳定,这强调了在进行全膝关节置换术时韧带平衡的重要性。在所有情况下,都进行了聚乙烯衬垫的交换。结论:种植体相关因素、手术技术及患者相关因素均可导致该罕见并发症的发生。肥胖、神经精神疾病和严重的外翻或内翻畸形是重要的患者相关危险因素。我们的案例也显示了这些风险因素。其中一些风险因素以及其他合并症因素都遇到了。在决定是否进行全膝关节置换术时,必须考虑到这些风险因素。这强调了在进行全膝关节置换术前对患者进行教育和共同决策的重要性。
{"title":"Dislocation after Posterior Stabilized Primary Total Knee Replacement: A Rare Complication in Four Cases.","authors":"W Spierenburg,&nbsp;E L A R Mutsaerts,&nbsp;J J A M van Raay","doi":"10.1155/2021/9935401","DOIUrl":"https://doi.org/10.1155/2021/9935401","url":null,"abstract":"<p><strong>Introduction: </strong>Dislocation of a total knee arthroplasty is a rare complication that has rarely been described, while the total knee arthroplasty is frequently performed. From literature, we know patient-related factors, like obesity, neuropsychiatric disease, and severe valgus or varus deformity, are associated with higher risk of dislocation. We show our cases for awareness of the risk factors for surgeons. <i>Case Presentations</i>. We present four patients with a dislocation after a total knee arthroplasty. We compare these case reports with previous literature and show the most important risk factors for these dislocations. In our cases, three of them suffered from obesity, which possibly has contributed to the dislocation. Three patients did have instability which emphasizes the importance of ligament balancing while performing a total knee replacement. In all cases, an exchange of the polyethylene liner was performed.</p><p><strong>Conclusion: </strong>Implant-related factors and surgical technique as well as patient-related factors can contribute to this uncommon complication. Obesity, neuropsychiatric disorders, and a severe valgus or varus deformity are important patient-related risk factors. Our cases show these risk factors too. Some of these risk factors were encountered as well as other comorbidity factors. Such risk factors must be taken into consideration when deciding whether to perform a total knee arthroplasty. This stresses the importance of patient education and shared decision-making before performing a total knee replacement.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9935401"},"PeriodicalIF":0.0,"publicationDate":"2021-10-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8528624/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39555440","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 1
Osteolysis following PE Wear of a Hastings Head on a Monoblock Hip Stem. PE在单块髋关节干上佩戴Hastings头后发生骨溶解。
Q4 ORTHOPEDICS Pub Date : 2021-10-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9989395
Sarah Fischer, Valerie Polster, Miriam Ruhr, Robert Hube, Michael M Morlock

We report a case of extended osteolysis, requiring a third revision of the left hip in an 85-year-old man 46 years after index operation. Major polyethylene (PE) wear occurred due to a missmatched combination of a bipolar Hastings head with a PE liner and head damage of the originally maintained stem. This case demonstrates that bipolar heads should not be used with PE cup liners since the respective bearing diameters cannot be guaranteed to match due to missing specifications. Furthermore, putting a Hastings head on an already damaged head of the stem should be omitted and rather the stem should initially be revised.

我们报告一例延伸性骨溶解,需要第三次左髋关节翻修的85岁男性46年后的指数手术。主要的聚乙烯(PE)磨损是由于双极Hastings封头与PE衬套的不匹配组合以及原始维护杆的封头损坏造成的。这个案例表明,双极头不应该与PE杯衬一起使用,因为由于缺少规格,各自的轴承直径不能保证匹配。此外,在已经损坏的阀杆上安装黑斯廷斯阀头应该被省略,而应该首先对阀杆进行修改。
{"title":"Osteolysis following PE Wear of a Hastings Head on a Monoblock Hip Stem.","authors":"Sarah Fischer,&nbsp;Valerie Polster,&nbsp;Miriam Ruhr,&nbsp;Robert Hube,&nbsp;Michael M Morlock","doi":"10.1155/2021/9989395","DOIUrl":"https://doi.org/10.1155/2021/9989395","url":null,"abstract":"<p><p>We report a case of extended osteolysis, requiring a third revision of the left hip in an 85-year-old man 46 years after index operation. Major polyethylene (PE) wear occurred due to a missmatched combination of a bipolar Hastings head with a PE liner and head damage of the originally maintained stem. This case demonstrates that bipolar heads should not be used with PE cup liners since the respective bearing diameters cannot be guaranteed to match due to missing specifications. Furthermore, putting a Hastings head on an already damaged head of the stem should be omitted and rather the stem should initially be revised.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9989395"},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516556/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39529126","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature. 小儿髓外硬膜外脊髓畸胎瘤1例报告及文献复习。
Q4 ORTHOPEDICS Pub Date : 2021-10-07 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6702972
David G Deckey, Andrea Fernandez, Nina J Lara, Steve Taylor, Jamal McClendon, David M Bennett

Background: Teratomas in the pediatric population are most commonly found in the sacrococcygeal region. Pediatric intraspinal teratomas, however, are an exceedingly rare central nervous system (CNS) neoplasm. The clinical presentation of these intraspinal neoplasms can vary significantly and thus can be difficult to identify in infants less than one year of age where verbal expression and motor development are still lacking. Case Description. A 7-month-old, previously healthy male presented with a thoracic scoliosis and an asymptomatic right midupper thoracic spinal prominence present since birth. MRI revealed an extensive heterogenous mass in the right epidural space from T5-T6 and the right paravertebral space, resulting in severe spinal stenosis. Outcome. Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. The final tumor was consistent with a mature teratoma. The surgical resection was performed without any immediate complications.

Conclusions: Extramedullary epidural teratomas are exceptionally rare tumors in the pediatric population. Clinical presentation can be ambiguous, particularly in an infant. MRI was useful in suggesting a teratoma as a potential diagnosis and for postoperative surveillance for recurrence. However, histopathological analysis remains the gold standard for definitive diagnosis. Surgical resection is the mainstay of treatment, especially in the setting of cord compression and progressive loss of motor function. Close follow-up is crucial to monitor for progressive spinal deformity or recurrence.

背景:儿童畸胎瘤最常见于骶尾骨区域。小儿脊柱内畸胎瘤是一种极为罕见的中枢神经系统肿瘤。这些椎管内肿瘤的临床表现可能差异很大,因此在一岁以下的婴儿中很难识别,因为他们的语言表达和运动发育仍然缺乏。案例描述。一个7个月大,以前健康的男性表现为胸椎侧凸和无症状的右胸椎中上部脊柱突出自出生以来。MRI显示右侧硬膜外肿物广泛分布于T5-T6及右侧椎旁间隙,导致严重椎管狭窄。结果。通过后路减压/椎板切除术完成肿瘤的完全切除,包括三节段神经切开术。最后的肿瘤符合成熟畸胎瘤。手术切除无任何直接并发症。结论:髓外硬膜外畸胎瘤在儿童中是极为罕见的肿瘤。临床表现可能不明确,特别是在婴儿中。MRI在提示畸胎瘤作为潜在的诊断和术后复发的监测是有用的。然而,组织病理学分析仍然是明确诊断的金标准。手术切除是治疗的主要方法,特别是在脊髓受压和运动功能进行性丧失的情况下。密切的随访对监测进行性脊柱畸形或复发至关重要。
{"title":"Pediatric Extramedullary Epidural Spinal Teratomas: A Case Report and Review of the Literature.","authors":"David G Deckey,&nbsp;Andrea Fernandez,&nbsp;Nina J Lara,&nbsp;Steve Taylor,&nbsp;Jamal McClendon,&nbsp;David M Bennett","doi":"10.1155/2021/6702972","DOIUrl":"https://doi.org/10.1155/2021/6702972","url":null,"abstract":"<p><strong>Background: </strong>Teratomas in the pediatric population are most commonly found in the sacrococcygeal region. Pediatric intraspinal teratomas, however, are an exceedingly rare central nervous system (CNS) neoplasm. The clinical presentation of these intraspinal neoplasms can vary significantly and thus can be difficult to identify in infants less than one year of age where verbal expression and motor development are still lacking. <i>Case Description</i>. A 7-month-old, previously healthy male presented with a thoracic scoliosis and an asymptomatic right midupper thoracic spinal prominence present since birth. MRI revealed an extensive heterogenous mass in the right epidural space from T5-T6 and the right paravertebral space, resulting in severe spinal stenosis. <i>Outcome</i>. Complete resection of the tumor, including a three-level neurotomy, was achieved by posterior decompression/laminectomy. The final tumor was consistent with a mature teratoma. The surgical resection was performed without any immediate complications.</p><p><strong>Conclusions: </strong>Extramedullary epidural teratomas are exceptionally rare tumors in the pediatric population. Clinical presentation can be ambiguous, particularly in an infant. MRI was useful in suggesting a teratoma as a potential diagnosis and for postoperative surveillance for recurrence. However, histopathological analysis remains the gold standard for definitive diagnosis. Surgical resection is the mainstay of treatment, especially in the setting of cord compression and progressive loss of motor function. Close follow-up is crucial to monitor for progressive spinal deformity or recurrence.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6702972"},"PeriodicalIF":0.0,"publicationDate":"2021-10-07","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8516554/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526291","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
A Case of Femoral Neck Insufficiency Fracture due to Tumor-Induced Osteomalacia. 肿瘤性骨软化致股骨颈不全骨折1例。
Q4 ORTHOPEDICS Pub Date : 2021-10-06 eCollection Date: 2021-01-01 DOI: 10.1155/2021/6668006
Yu Inoue, Tomoaki Fukui, Keisuke Oe, Shinya Hayashi, Teruya Kawamoto, Ryosuke Kuroda, Takahiro Niikura

Tumor-induced osteomalacia (TIO) is a rare skeletal disease caused by hypersecretion of fibroblast growth factor 23 (FGF-23) from neoplasms of mesenchymal origin; patients with TIO present with insufficiency fractures, progressive bone pain, and delayed fracture unions. Herein, we report the case of a 48-year-old man with an insufficiency fracture in his left femoral neck associated with TIO. The causative tumor located in the patient's maxillary sinus had been resected; however, complete resection was impossible due to the location of the tumor. Therefore, the patient's osteomalacia persisted, and he experienced a left femoral neck fracture in the absence of severe trauma. Because delayed fracture union was anticipated in this patient, we performed an internal fixation using an implant with a lateral plate for angular stability and multiple screws for rotational stability. Although fracture union took 15 months, the patient's postoperative course was uneventful, and he could walk without any symptoms or assistance at his most recent follow-up 30 months after surgery. In TIO, hypersecretion of FGF-23 leads to increased renal excretion of phosphorus, increased bone resorption of calcium and phosphorus, decreased osteoblastic bone mineralization, and decreased gastrointestinal absorption of calcium and phosphorus, leading to insufficiency fractures and delayed fracture unions. Diagnosis of TIO is often delayed due to its rarity and vague symptoms. Total resection of the causative tumor is the optimal treatment; however, in cases wherein complete tumor resection is impossible, drug therapy may be insufficient, and the underlying TIO pathology, including bone fragility, may persist. Early diagnosis of TIO is important for preventing insufficiency fractures; however, when fractures are unavoidable, the surgical treatment of femoral neck fractures in patients with osteomalacia should account for a longer time frame for complete fracture union and therefore utilize implants with sufficient stability.

肿瘤诱导的骨软化症(TIO)是一种罕见的骨骼疾病,由间充质源性肿瘤纤维母细胞生长因子23 (FGF-23)分泌过多引起;TIO患者表现为骨折不全、进行性骨痛和骨折愈合延迟。在此,我们报告一例48岁男性左股骨颈不全骨折合并TIO。位于患者上颌窦的肿瘤已被切除;然而,由于肿瘤的位置,完全切除是不可能的。因此,患者的骨软化症持续存在,他在没有严重创伤的情况下经历了左股骨颈骨折。由于预计该患者骨折愈合延迟,我们使用带侧钢板的内固定物进行角度稳定,并使用多枚螺钉进行旋转稳定。虽然骨折愈合花了15个月的时间,但患者的术后过程平淡无奇,在术后30个月的最近一次随访中,他可以在没有任何症状或辅助的情况下行走。在TIO中,FGF-23的高分泌导致肾磷排泄增加,钙磷骨吸收增加,成骨细胞骨矿化减少,钙磷胃肠道吸收减少,导致骨折功能不全和骨折愈合延迟。由于其罕见和症状模糊,TIO的诊断经常被延迟。肿瘤完全切除是最佳治疗方法;然而,在不可能完全切除肿瘤的情况下,药物治疗可能不够,潜在的TIO病理,包括骨脆性,可能会持续存在。早期诊断对预防不完全性骨折有重要意义;然而,当骨折不可避免时,骨软化患者股骨颈骨折的手术治疗应考虑到骨折完全愈合的较长时间框架,因此使用具有足够稳定性的植入物。
{"title":"A Case of Femoral Neck Insufficiency Fracture due to Tumor-Induced Osteomalacia.","authors":"Yu Inoue,&nbsp;Tomoaki Fukui,&nbsp;Keisuke Oe,&nbsp;Shinya Hayashi,&nbsp;Teruya Kawamoto,&nbsp;Ryosuke Kuroda,&nbsp;Takahiro Niikura","doi":"10.1155/2021/6668006","DOIUrl":"https://doi.org/10.1155/2021/6668006","url":null,"abstract":"<p><p>Tumor-induced osteomalacia (TIO) is a rare skeletal disease caused by hypersecretion of fibroblast growth factor 23 (FGF-23) from neoplasms of mesenchymal origin; patients with TIO present with insufficiency fractures, progressive bone pain, and delayed fracture unions. Herein, we report the case of a 48-year-old man with an insufficiency fracture in his left femoral neck associated with TIO. The causative tumor located in the patient's maxillary sinus had been resected; however, complete resection was impossible due to the location of the tumor. Therefore, the patient's osteomalacia persisted, and he experienced a left femoral neck fracture in the absence of severe trauma. Because delayed fracture union was anticipated in this patient, we performed an internal fixation using an implant with a lateral plate for angular stability and multiple screws for rotational stability. Although fracture union took 15 months, the patient's postoperative course was uneventful, and he could walk without any symptoms or assistance at his most recent follow-up 30 months after surgery. In TIO, hypersecretion of FGF-23 leads to increased renal excretion of phosphorus, increased bone resorption of calcium and phosphorus, decreased osteoblastic bone mineralization, and decreased gastrointestinal absorption of calcium and phosphorus, leading to insufficiency fractures and delayed fracture unions. Diagnosis of TIO is often delayed due to its rarity and vague symptoms. Total resection of the causative tumor is the optimal treatment; however, in cases wherein complete tumor resection is impossible, drug therapy may be insufficient, and the underlying TIO pathology, including bone fragility, may persist. Early diagnosis of TIO is important for preventing insufficiency fractures; however, when fractures are unavoidable, the surgical treatment of femoral neck fractures in patients with osteomalacia should account for a longer time frame for complete fracture union and therefore utilize implants with sufficient stability.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"6668006"},"PeriodicalIF":0.0,"publicationDate":"2021-10-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8514931/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39526290","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Complications after Dynamic Hip Screw Osteosynthesis of Proximal Femoral Fractures at Army Instructional Hospital-Libreville. 利伯维尔陆军教学医院股骨近端骨折动态髋螺钉骨合成术后并发症。
Q4 ORTHOPEDICS Pub Date : 2021-10-04 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4177203
F M Bombah, M Diawara, B Y Ekani, T Nana, A Mikiela

The DHS system is an effective means of open reduction and internal fixation of proximal femur fractures. Postoperative complications are little described and deserve to be studied for better preventive and curative treatment. We report the observations of five (5) patients who presented postoperative complications specific to the DHS system at army instructional Hospital-Libreville. These described complications are related to deterioration of internal fixation leading to callus, nonunion, or infection. Those found are the cut out phenomenon, avascular necrosis of the femoral head, and the fracture of the DHS system. All these complications required surgical revision without functional repercussions at the last follow-up. Complications of internal fixation by the DHS system can be avoided by rigorous asepsis, adequate indications for surgery, and rigorous surgical techniques. Good management can restore hip function.

DHS 系统是股骨近端骨折切开复位和内固定的有效手段。但对术后并发症的描述却很少,为了更好地预防和治疗,我们应该对这些并发症进行研究。我们报告了在利伯维尔陆军教导医院对五(5)名出现 DHS 系统术后并发症患者的观察结果。这些并发症都与内固定恶化导致胼胝、不愈合或感染有关。这些并发症包括切出现象、股骨头血管性坏死和DHS系统骨折。所有这些并发症在最后一次随访时都需要进行手术翻修,但未对功能造成影响。通过严格的无菌操作、充分的手术指征和严谨的手术技巧,DHS 系统内固定的并发症是可以避免的。良好的管理可以恢复髋关节功能。
{"title":"Complications after Dynamic Hip Screw Osteosynthesis of Proximal Femoral Fractures at Army Instructional Hospital-Libreville.","authors":"F M Bombah, M Diawara, B Y Ekani, T Nana, A Mikiela","doi":"10.1155/2021/4177203","DOIUrl":"10.1155/2021/4177203","url":null,"abstract":"<p><p>The DHS system is an effective means of open reduction and internal fixation of proximal femur fractures. Postoperative complications are little described and deserve to be studied for better preventive and curative treatment. We report the observations of five (5) patients who presented postoperative complications specific to the DHS system at army instructional Hospital-Libreville. These described complications are related to deterioration of internal fixation leading to callus, nonunion, or infection. Those found are the cut out phenomenon, avascular necrosis of the femoral head, and the fracture of the DHS system. All these complications required surgical revision without functional repercussions at the last follow-up. Complications of internal fixation by the DHS system can be avoided by rigorous asepsis, adequate indications for surgery, and rigorous surgical techniques. Good management can restore hip function.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"4177203"},"PeriodicalIF":0.0,"publicationDate":"2021-10-04","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8505106/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39515699","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 0
Salvaging the Digit in Invasive Subungual Malignancies Using a Triple Technique under Awake Local Anesthesia. 清醒局麻下三合一技术抢救侵入性甲下恶性肿瘤的手指。
Q4 ORTHOPEDICS Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/4648627
Samer Abdel Al, Mohamad K Abou Chaar, Ala'a Aldeen Alkhatib, Muhamad Al-Qawasmi, Mohammad Barham, Sameer Yaser, Samer Salah, Abed Al Raheem Suleiman, Wafa Asha

Introduction: Amputation for subungual malignancy (SUM) was thought to be the gold standard in preventing recurrence and metastasis. The rationale behind this aggressive treatment was never based on scientific evidence. Even though multiple recent studies supported more conservative management by illustrating successful results of the digit salvage technique, especially for "in situ" SUM, this salvage approach is not well supported for the more aggressive type of the "invasive" SUM; herein, we salvaged two cases of "invasive" SUM. Case Presentation. We present two cases of invasive SUM without radiographic evidence of intraosseous involvement, where we avoided digit amputation for both invasive subungual squamous cell carcinoma of the thumb and invasive subungual melanoma of the ring finger. Both were salvaged by using a triple technique under awake local anesthesia which included (I) radical excision of the nail bed unit including both eponychium and periosteum, (II) dorsal cortical bone shaving using a high-speed burr for the distal phalanx, and (III) flap coverage. Brunelli flap was used for the thumb in the first case, and V-Y plasty combined with proximal nail fold advancement flap was used for the ring finger in the second case. There was no evidence of local or distant recurrence, with a good functional outcome after 2.5 years in the first case and 2 years in the second.

Conclusion: Ensuring complete resection with negative margins while preserving the functionality of the affected digit is considered to be the optimal challenge in treating "invasive" subungual malignancies. These two case reports contribute by reporting a successful digit salvage. The safety of this procedure could be confirmed by larger series and longer follow-up periods.

趾下恶性肿瘤(SUM)截肢被认为是预防复发和转移的金标准。这种激进疗法背后的理论基础从来都没有科学依据。尽管最近的多项研究通过说明手指保留技术的成功结果支持更保守的管理,特别是对于“原位”SUM,但这种保留方法并不很好地支持更具侵略性的“侵入性”SUM;在此,我们抢救了两例“侵入性”SUM。案例演示。我们报告了两例侵袭性SUM,没有骨内受累的影像学证据,我们避免了拇指的侵袭性甲下鳞状细胞癌和无名指的侵袭性甲下黑色素瘤的手指截肢。两例患者均在清醒局部麻醉下采用三合一技术进行修复,包括(I)根治性切除甲床单元,包括掌骨和骨膜,(II)使用高速毛刺对远端指骨进行背侧皮质骨刮除,以及(III)皮瓣覆盖。1例拇指采用Brunelli皮瓣,2例无名指采用V-Y成形术联合近端甲襞推进皮瓣。没有局部或远处复发的证据,第一例2.5年和第二例2年后功能预后良好。结论:在保留患指功能的同时,确保负缘完全切除被认为是治疗“侵袭性”甲下恶性肿瘤的最佳挑战。这两个病例报告通过报告成功的手指抢救作出贡献。该方法的安全性可以通过更大的系列和更长的随访期来证实。
{"title":"Salvaging the Digit in Invasive Subungual Malignancies Using a Triple Technique under Awake Local Anesthesia.","authors":"Samer Abdel Al,&nbsp;Mohamad K Abou Chaar,&nbsp;Ala'a Aldeen Alkhatib,&nbsp;Muhamad Al-Qawasmi,&nbsp;Mohammad Barham,&nbsp;Sameer Yaser,&nbsp;Samer Salah,&nbsp;Abed Al Raheem Suleiman,&nbsp;Wafa Asha","doi":"10.1155/2021/4648627","DOIUrl":"https://doi.org/10.1155/2021/4648627","url":null,"abstract":"<p><strong>Introduction: </strong>Amputation for subungual malignancy (SUM) was thought to be the gold standard in preventing recurrence and metastasis. The rationale behind this aggressive treatment was never based on scientific evidence. Even though multiple recent studies supported more conservative management by illustrating successful results of the digit salvage technique, especially for \"in situ\" SUM, this salvage approach is not well supported for the more aggressive type of the \"invasive\" SUM; herein, we salvaged two cases of \"invasive\" SUM. <i>Case Presentation</i>. We present two cases of invasive SUM without radiographic evidence of intraosseous involvement, where we avoided digit amputation for both invasive subungual squamous cell carcinoma of the thumb and invasive subungual melanoma of the ring finger. Both were salvaged by using a triple technique under awake local anesthesia which included (I) radical excision of the nail bed unit including both eponychium and periosteum, (II) dorsal cortical bone shaving using a high-speed burr for the distal phalanx, and (III) flap coverage. Brunelli flap was used for the thumb in the first case, and V-Y plasty combined with proximal nail fold advancement flap was used for the ring finger in the second case. There was no evidence of local or distant recurrence, with a good functional outcome after 2.5 years in the first case and 2 years in the second.</p><p><strong>Conclusion: </strong>Ensuring complete resection with negative margins while preserving the functionality of the affected digit is considered to be the optimal challenge in treating \"invasive\" subungual malignancies. These two case reports contribute by reporting a successful digit salvage. The safety of this procedure could be confirmed by larger series and longer follow-up periods.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"4648627"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497149/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505847","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 3
Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient. 成人肩胛骨血管瘤样纤维组织细胞瘤伴EWSR1-CREB1融合1例。
Q4 ORTHOPEDICS Pub Date : 2021-09-30 eCollection Date: 2021-01-01 DOI: 10.1155/2021/9434222
Hiroshi Kobayashi, Naohiro Makise, Aya Shinozaki-Ushiku, Yuki Ishibashi, Masachika Ikegami, Shinji Kohsaka, Tetsuo Ushiku, Katsutoshi Oda, Kiyoshi Miyagawa, Hiroyuki Aburatani, Hiroyuki Mano, Sakae Tanaka

Background: Angiomatoid fibrous histiocytoma (AFH) is a rare intermediate malignant tumor that arises mainly in soft tissues, especially in the superficial extremities of patients younger than 30 years. There have been a few reports of AFH arising from sites other than soft tissue, including bone, and unusual site and age make it difficult to diagnose this rare tumor. Case Presentation. Here, we present a case of a 54-year-old man who was examined for chest pain, and computed tomography (CT) incidentally detected a bone tumor at the scapula with destruction of cortical bone and invasion into soft tissue. Magnetic resonance imaging revealed multiple cystic components with fluid-fluid levels. FDG-PET showed uptake at the axillary lymph node. The CT-guided needle biopsy revealed spindle cell sarcoma on histopathology. After neoadjuvant chemotherapy, a scapulectomy was performed. The final postresection histopathological diagnosis was the same as the preoperative diagnosis, and no obvious chemotherapeutic effect was observed. Next-generation sequencing of RNA isolated from paraffin-embedded tumor tissue revealed that these lesions harbored the EWSR1-CREB1 fusion gene, and the tumor was diagnosed as AFH. C-reactive protein level, which was elevated preoperatively, decreased after the operation, and there was no recurrence or metastasis 5 years after the treatment.

Conclusion: The diagnosis of AFH is difficult when the tumor has an atypical presentation. Comprehensive genomic analysis, especially RNA sequencing, is efficient in diagnosing this rare tumor. Moreover, magnetic resonance imaging findings identical to AFH in soft tissue, the presence of paraneoplastic symptoms such as elevated inflammatory markers, and lymph node swelling were clues towards suspecting this tumor.

背景:血管瘤样纤维组织细胞瘤(AFH)是一种罕见的中间恶性肿瘤,主要发生在软组织,特别是30岁以下患者的肢体浅表。有一些报道称,AFH发生在软组织以外的部位,包括骨骼,而不寻常的部位和年龄使得这种罕见的肿瘤难以诊断。案例演示。在此,我们报告一个54岁男性的病例,他在检查胸痛时,计算机断层扫描(CT)偶然发现肩胛骨处有骨肿瘤,并破坏皮质骨并侵入软组织。磁共振成像显示多个囊性成分与液-液水平。FDG-PET显示腋窝淋巴结摄取。ct引导下穿刺活检病理显示为梭形细胞肉瘤。新辅助化疗后,行肩胛骨切除术。最终的术后组织病理学诊断与术前诊断相同,未见明显的化疗效果。从石蜡包埋的肿瘤组织中分离的RNA进行新一代测序,发现这些病变携带EWSR1-CREB1融合基因,诊断为AFH。c反应蛋白水平术前升高,术后下降,治疗5年后无复发转移。结论:当肿瘤表现不典型时,诊断AFH较为困难。全面的基因组分析,特别是RNA测序,对诊断这种罕见的肿瘤是有效的。此外,软组织中与AFH相同的磁共振成像结果,如炎症标志物升高和淋巴结肿胀等副肿瘤症状的存在,都是怀疑该肿瘤的线索。
{"title":"Scapular Angiomatoid Fibrous Histiocytoma with EWSR1-CREB1 Fusion in an Adult Patient.","authors":"Hiroshi Kobayashi,&nbsp;Naohiro Makise,&nbsp;Aya Shinozaki-Ushiku,&nbsp;Yuki Ishibashi,&nbsp;Masachika Ikegami,&nbsp;Shinji Kohsaka,&nbsp;Tetsuo Ushiku,&nbsp;Katsutoshi Oda,&nbsp;Kiyoshi Miyagawa,&nbsp;Hiroyuki Aburatani,&nbsp;Hiroyuki Mano,&nbsp;Sakae Tanaka","doi":"10.1155/2021/9434222","DOIUrl":"https://doi.org/10.1155/2021/9434222","url":null,"abstract":"<p><strong>Background: </strong>Angiomatoid fibrous histiocytoma (AFH) is a rare intermediate malignant tumor that arises mainly in soft tissues, especially in the superficial extremities of patients younger than 30 years. There have been a few reports of AFH arising from sites other than soft tissue, including bone, and unusual site and age make it difficult to diagnose this rare tumor. <i>Case Presentation</i>. Here, we present a case of a 54-year-old man who was examined for chest pain, and computed tomography (CT) incidentally detected a bone tumor at the scapula with destruction of cortical bone and invasion into soft tissue. Magnetic resonance imaging revealed multiple cystic components with fluid-fluid levels. FDG-PET showed uptake at the axillary lymph node. The CT-guided needle biopsy revealed spindle cell sarcoma on histopathology. After neoadjuvant chemotherapy, a scapulectomy was performed. The final postresection histopathological diagnosis was the same as the preoperative diagnosis, and no obvious chemotherapeutic effect was observed. Next-generation sequencing of RNA isolated from paraffin-embedded tumor tissue revealed that these lesions harbored the <i>EWSR1-CREB1</i> fusion gene, and the tumor was diagnosed as AFH. C-reactive protein level, which was elevated preoperatively, decreased after the operation, and there was no recurrence or metastasis 5 years after the treatment.</p><p><strong>Conclusion: </strong>The diagnosis of AFH is difficult when the tumor has an atypical presentation. Comprehensive genomic analysis, especially RNA sequencing, is efficient in diagnosing this rare tumor. Moreover, magnetic resonance imaging findings identical to AFH in soft tissue, the presence of paraneoplastic symptoms such as elevated inflammatory markers, and lymph node swelling were clues towards suspecting this tumor.</p>","PeriodicalId":30287,"journal":{"name":"Case Reports in Orthopedics","volume":"2021 ","pages":"9434222"},"PeriodicalIF":0.0,"publicationDate":"2021-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8497169/pdf/","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"39505850","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"OA","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
引用次数: 2
期刊
Case Reports in Orthopedics
全部 Acc. Chem. Res. ACS Applied Bio Materials ACS Appl. Electron. Mater. ACS Appl. Energy Mater. ACS Appl. Mater. Interfaces ACS Appl. Nano Mater. ACS Appl. Polym. Mater. ACS BIOMATER-SCI ENG ACS Catal. ACS Cent. Sci. ACS Chem. Biol. ACS Chemical Health & Safety ACS Chem. Neurosci. ACS Comb. Sci. ACS Earth Space Chem. ACS Energy Lett. ACS Infect. Dis. ACS Macro Lett. ACS Mater. Lett. ACS Med. Chem. Lett. ACS Nano ACS Omega ACS Photonics ACS Sens. ACS Sustainable Chem. Eng. ACS Synth. Biol. Anal. Chem. BIOCHEMISTRY-US Bioconjugate Chem. BIOMACROMOLECULES Chem. Res. Toxicol. Chem. Rev. Chem. Mater. CRYST GROWTH DES ENERG FUEL Environ. Sci. Technol. Environ. Sci. Technol. Lett. Eur. J. Inorg. Chem. IND ENG CHEM RES Inorg. Chem. J. Agric. Food. Chem. J. Chem. Eng. Data J. Chem. Educ. J. Chem. Inf. Model. J. Chem. Theory Comput. J. Med. Chem. J. Nat. Prod. J PROTEOME RES J. Am. Chem. Soc. LANGMUIR MACROMOLECULES Mol. Pharmaceutics Nano Lett. Org. Lett. ORG PROCESS RES DEV ORGANOMETALLICS J. Org. Chem. J. Phys. Chem. J. Phys. Chem. A J. Phys. Chem. B J. Phys. Chem. C J. Phys. Chem. Lett. Analyst Anal. Methods Biomater. Sci. Catal. Sci. Technol. Chem. Commun. Chem. Soc. Rev. CHEM EDUC RES PRACT CRYSTENGCOMM Dalton Trans. Energy Environ. Sci. ENVIRON SCI-NANO ENVIRON SCI-PROC IMP ENVIRON SCI-WAT RES Faraday Discuss. Food Funct. Green Chem. Inorg. Chem. Front. Integr. Biol. J. Anal. At. Spectrom. J. Mater. Chem. A J. Mater. Chem. B J. Mater. Chem. C Lab Chip Mater. Chem. Front. Mater. Horiz. MEDCHEMCOMM Metallomics Mol. Biosyst. Mol. Syst. Des. Eng. Nanoscale Nanoscale Horiz. Nat. Prod. Rep. New J. Chem. Org. Biomol. Chem. Org. Chem. Front. PHOTOCH PHOTOBIO SCI PCCP Polym. Chem.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1