Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3463
K. Krolikowski, C. Barnett, J. Yang, B. Gordon, H. Shah, P. Pamar, I. Atandi, D. Collazo, A. Lehr, L. Segal, S. Brosnahan
{"title":"Incidence and Risk Factors of Acute CVA Associated With ARDS Secondary to SARS-CoV-2","authors":"K. Krolikowski, C. Barnett, J. Yang, B. Gordon, H. Shah, P. Pamar, I. Atandi, D. Collazo, A. Lehr, L. Segal, S. Brosnahan","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3463","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3463","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"14 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130558538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3474
T. Bassi, E. Rohrs, M. Parfait, S. Reynolds, J. Mayaux, M. Decavèle, T. Similowski, A. Demoule, M. Dres
{"title":"Increased Alpha Power in the Frontal Lobes With Diaphragm Neurostimulation in ARDS Patients","authors":"T. Bassi, E. Rohrs, M. Parfait, S. Reynolds, J. Mayaux, M. Decavèle, T. Similowski, A. Demoule, M. Dres","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3474","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3474","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"1 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130897200","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3461
S. Yu, O. Lin, T. Miller, W. Fang, G. Perkowski, C. Gates, B. Balakrishnan
Background: Thromboelastography (TEG) revolutionized the resuscitation of critically ill trauma and cirrhotic patients by improving blood product utilization and survival outcomes. There is limited data on the application and outcomes of non-trauma critical care (NTCC) patients with TEG use. This study compares the blood product utilization, mortality, and other outcomes of NTCC patients using TEG or CCT-guided transfusion. Methods: This is a single-center retrospective observational exploratory study of adult NTCC patients admitted to the medical intensive care unit in a rural academic center. Eligible patients received transfusion of blood products (BPs) guided by CCT or TEG studies. The primary outcome compared BPs transfused. Secondary outcomes included methods to achieve hemostasis, 28-day readmission rate after discharge, and 28-day survival. Results: TEG was used in 80 (70.8%) patients. The TEG group received 4.5 more units of BPs than the CCT group (p=0.003). A clinically significant difference in BPs transfused was seen in packed red blood cells (p=0.064), platelets (p=0.003), and fresh frozen plasma (p=0.020). The methods to achieve hemostasis between the groups were statistically significant (p=0.021). The 28-day readmission-free rate was similar (42.5% vs. 54.5%, TEG vs. CCT, p=0.301), as was the 28-day survival after discharge (p=0.078) in both groups. Conclusions: TEG-guided transfusion increased the number of BPs transfused compared to CCT in NTCC patients. No difference between the two groups in achieving hemostasis, 28-day readmission rate, or 28-day mortality was observed. This study highlights the need to further analyze TEGguided resuscitation prior to adopting TEG into routine practice in NTCC settings.
背景:血栓弹性成像(TEG)通过改善血液制品利用率和生存结果，彻底改变了危重创伤和肝硬化患者的复苏。关于非创伤重症监护(NTCC)患者使用TEG的应用和结果的数据有限。本研究比较了使用TEG或cct引导输血的NTCC患者的血液制品利用率、死亡率和其他结果。方法:对某农村学术中心重症监护病房收治的成年NTCC患者进行单中心回顾性观察性探索性研究。符合条件的患者接受由CCT或TEG研究指导的血液制品(bp)输血。主要终点比较输注bp。次要结局包括止血方法、出院后28天再入院率和28天生存率。结果:应用TEG治疗80例(70.8%)。TEG组比CCT组多4.5个单位bp (p=0.003)。血浆中bp值的差异有临床意义(p=0.064)、血小板(p=0.003)和新鲜冷冻血浆(p=0.020)。两组止血方法差异有统计学意义(p=0.021)。两组28天无再入院率相似(42.5% vs. 54.5%， TEG vs. CCT, p=0.301)，出院后28天生存率相似(p=0.078)。结论:与CCT相比，teg引导的输注增加了NTCC患者输注bp的数量。两组在止血、28天再入院率和28天死亡率方面均无差异。本研究强调了在NTCC环境中将TEG纳入常规实践之前，需要进一步分析TEG引导下的复苏。
{"title":"Does Thromboelastography in Non-trauma Critical Care Patients Promote the Judicious Use of Blood Products?","authors":"S. Yu, O. Lin, T. Miller, W. Fang, G. Perkowski, C. Gates, B. Balakrishnan","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3461","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3461","url":null,"abstract":"Background: Thromboelastography (TEG) revolutionized the resuscitation of critically ill trauma and cirrhotic patients by improving blood product utilization and survival outcomes. There is limited data on the application and outcomes of non-trauma critical care (NTCC) patients with TEG use. This study compares the blood product utilization, mortality, and other outcomes of NTCC patients using TEG or CCT-guided transfusion. Methods: This is a single-center retrospective observational exploratory study of adult NTCC patients admitted to the medical intensive care unit in a rural academic center. Eligible patients received transfusion of blood products (BPs) guided by CCT or TEG studies. The primary outcome compared BPs transfused. Secondary outcomes included methods to achieve hemostasis, 28-day readmission rate after discharge, and 28-day survival. Results: TEG was used in 80 (70.8%) patients. The TEG group received 4.5 more units of BPs than the CCT group (p=0.003). A clinically significant difference in BPs transfused was seen in packed red blood cells (p=0.064), platelets (p=0.003), and fresh frozen plasma (p=0.020). The methods to achieve hemostasis between the groups were statistically significant (p=0.021). The 28-day readmission-free rate was similar (42.5% vs. 54.5%, TEG vs. CCT, p=0.301), as was the 28-day survival after discharge (p=0.078) in both groups. Conclusions: TEG-guided transfusion increased the number of BPs transfused compared to CCT in NTCC patients. No difference between the two groups in achieving hemostasis, 28-day readmission rate, or 28-day mortality was observed. This study highlights the need to further analyze TEGguided resuscitation prior to adopting TEG into routine practice in NTCC settings.","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"10 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132879659","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3478
S. Pothapragada, L. Ayers, J. Chang, X. Geng, C. Shults, A. Zaaqoq
{"title":"Risk Factors for Stroke Development After Thoracic Aortic Surgery","authors":"S. Pothapragada, L. Ayers, J. Chang, X. Geng, C. Shults, A. Zaaqoq","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3478","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3478","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"402 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116028803","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3459
C. Wakefield, N. Yun, J. Borgia, A. Varma, C. Seder, T. M. Kuzel
{"title":"Neutrophil to Lymphocyte Ratio Is Associated With Mortality in Patients Undergoing Treatment for Hemato-oncologic Malignancies and Admitted for COVID 19","authors":"C. Wakefield, N. Yun, J. Borgia, A. Varma, C. Seder, T. M. Kuzel","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3459","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3459","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"28 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"125851276","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3470
A.J. Kumar, S. Thomson, M. Hepokoski
{"title":"Utilizing Renal Micropuncture to Understand Ventilator Induced Kidney Injury","authors":"A.J. Kumar, S. Thomson, M. Hepokoski","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3470","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3470","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"23 15 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"130234309","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3471
H. Zhang, J. Zhang, J. Li, Z. Mao, J. Qian, C. Zong, H. Sun, B. Yuan
{"title":"Multi-omics Analyses Reveal the Mechanisms of Ultra-early Stage Kidney Toxicity by Diquat","authors":"H. Zhang, J. Zhang, J. Li, Z. Mao, J. Qian, C. Zong, H. Sun, B. Yuan","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3471","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3471","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"78 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"132707631","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3475
T. Bassi, E. Rohrs, M. Parfait, S. Reynolds, J. Mayaux, M. Decavèle, T. Similowski, A. Demoule, M. Dres
{"title":"Increased Parasympathetic Activity in the Brain Vessels With Diaphragm Neurostimulation","authors":"T. Bassi, E. Rohrs, M. Parfait, S. Reynolds, J. Mayaux, M. Decavèle, T. Similowski, A. Demoule, M. Dres","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3475","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3475","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"168 3 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"116271716","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3477
P. Biselli, R. S. Nóbrega
{"title":"Measuring Changes in Respiratory Effort Using Central Venous Pressure in Patients on Non-invasive Ventilation After Extubation","authors":"P. Biselli, R. S. Nóbrega","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3477","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3477","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"16 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"122342224","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Pub Date : 2023-05-01DOI: 10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3465
T. Mutoh, K. Sasaki, J. Moroi, T. Ishikawa
{"title":"Volumetric Patterns and Prognosis of Neurogenic Pulmonary Edema After Subarachnoid Hemorrhage","authors":"T. Mutoh, K. Sasaki, J. Moroi, T. Ishikawa","doi":"10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3465","DOIUrl":"https://doi.org/10.1164/ajrccm-conference.2023.207.1_meetingabstracts.a3465","url":null,"abstract":"","PeriodicalId":309531,"journal":{"name":"B46. OTHER SPECIALTIES IN THE ICU: TOPICS IN NEPHROLOGY, HEMATOLOGY/ONCOLOGY, AND MORE","volume":"170 1","pages":"0"},"PeriodicalIF":0.0,"publicationDate":"2023-05-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"133991040","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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